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Total number of protein in "GO:0008284" GO term:  822

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0008284 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACER2 ACER2 Q5QJU3 Alkaline ceramidase 2 chr9 GO:0008284 Not Cancer Driver No 27 0.098 0 0 0.0 0
ACER3 ACER3 Q9NUN7 Alkaline ceramidase 3 chr11 GO:0008284 Not Cancer Driver No 28 0.105 0 0 0.0 1
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0008284 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADA ADA P00813 Adenosine deaminase chr20 GO:0008284 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0008284 Not Cancer Driver No 88 0.118 156 20 0.128 4
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0008284 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAMTS1 ADAMTS1 Q9UHI8 A disintegrin and metalloproteinase with thrombospondin motifs 1 chr21 GO:0008284 Not Cancer Driver No 135 0.14 272 32 0.118 0
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:0008284 Not Cancer Driver No 64 0.092 67 4 0.06 9
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0008284 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADRA1D ADRA1D P25100 Alpha-1D adrenergic receptor chr20 GO:0008284 Not Cancer Driver No 62 0.108 189 19 0.101 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0008284 Not Cancer Driver No 67 0.144 161 10 0.062 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0008284 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGGF1 AGGF1 Q8N302 Angiogenic factor with G patch and FHA domains 1 chr5 GO:0008284 Not Cancer Driver No 100 0.14 582 80 0.137 1
AGT AGT P01019 Angiotensinogen chr1 GO:0008284 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTR1_ENST00000349243 AGTR1 P30556 Type-1 angiotensin II receptor chr3 GO:0008284 Not Cancer Driver No 95 0.265 0 0 0.0 1
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0008284 Not Cancer Driver No 14 0.095 61 6 0.098 0
AKIRIN2 AKIRIN2 Q53H80 Akirin-2 chr6 GO:0008284 Not Cancer Driver No 21 0.103 119 11 0.092 0
AKR1C2 AKR1C2 P52895 Aldo-keto reductase family 1 member C2 chr10 GO:0008284 Not Cancer Driver No 32 0.099 1 0 0.0 4
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0008284 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0008284 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0008284 Census Yes 77 0.16 84 9 0.107 2
AKT3_ENST00000366539 AKT3 Q9Y243 RAC-gamma serine/threonine-protein kinase chr1 GO:0008284 Census, Compendium Yes 92 0.192 131 24 0.183 3
ALDH1A2 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 GO:0008284 Not Cancer Driver No 100 0.193 56 13 0.232 0
ANG ANG P03950 Angiogenin chr14 GO:0008284 Not Cancer Driver No 19 0.129 36 2 0.056 14
APELA APELA P0DMC3 Apelin receptor early endogenous ligand chr4 GO:0008284 Not Cancer Driver No 1 0.019 0 0 0.0 0
APLN APLN Q9ULZ1 Apelin chrX GO:0008284 Not Cancer Driver No 8 0.104 51 6 0.118 0
APLNR APLNR P35414 Apelin receptor chr11 GO:0008284 Not Cancer Driver No 96 0.253 29 8 0.276 0
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0008284 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP11 AQP11 Q8NBQ7 Aquaporin-11 chr11 GO:0008284 Not Cancer Driver No 23 0.085 0 0 0.0 0
AR AR P10275 Androgen receptor chrX GO:0008284 Census, Compendium Yes 196 0.213 443 88 0.199 169
AREG AREG P15514 Amphiregulin chr4 GO:0008284 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0008284 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0008284 Census Yes 77 0.098 511 56 0.11 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0008284 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASH2L ASH2L Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 chr8 GO:0008284 Not Cancer Driver No 95 0.151 293 39 0.133 0
ASPM ASPM Q8IZT6 Abnormal spindle-like microcephaly-associated protein chr1 GO:0008284 Not Cancer Driver No 554 0.159 424 67 0.158 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0008284 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0008284 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0008284 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATXN1L ATXN1L P0C7T5 Ataxin-1-like chr16 GO:0008284 Not Cancer Driver No 30 0.044 476 19 0.04 0
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0008284 Not Cancer Driver No 14 0.085 26 0 0.0 39
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0008284 Not Cancer Driver No 105 0.251 68 25 0.368 0
AVPR2_ENST00000337474 AVPR2 P30518 Vasopressin V2 receptor chrX GO:0008284 Not Cancer Driver No 58 0.156 56 7 0.125 84
B4GALT1 B4GALT1 P15291 Beta-1,4-galactosyltransferase 1 chr9 GO:0008284 Not Cancer Driver No 38 0.095 129 13 0.101 0
BAMBI BAMBI Q13145 BMP and activin membrane-bound inhibitor homolog chr10 GO:0008284 Not Cancer Driver No 42 0.162 31 7 0.226 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0008284 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0008284 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0008284 Census, Compendium Yes 134 0.19 328 67 0.204 0
BIRC5_ENST00000350051 BIRC5 O15392 Baculoviral IAP repeat-containing protein 5 chr17 GO:0008284 Not Cancer Driver No 20 0.141 49 6 0.122 0
BIRC6 BIRC6 Q9NR09 Baculoviral IAP repeat-containing protein 6 chr2 GO:0008284 Census, Compendium Yes 640 0.132 1312 170 0.13 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 GO:0008284 Not Cancer Driver No 50 0.153 150 30 0.2 0
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0008284 Not Cancer Driver No 88 0.208 87 13 0.149 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0008284 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0008284 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0008284 Census Yes 163 0.359 112 62 0.554 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0008284 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0008284 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0008284 Compendium Yes 141 0.136 601 70 0.116 19
BNC1 BNC1 Q01954 Zinc finger protein basonuclin-1 chr15 GO:0008284 Not Cancer Driver No 195 0.196 530 111 0.209 0
BRK1 BRK1 Q8WUW1 Protein BRICK1 chr3 GO:0008284 Not Cancer Driver No 7 0.093 14 1 0.071 0
BST1 BST1 Q10588 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 chr4 GO:0008284 Not Cancer Driver No 40 0.126 11 0 0.0 0
BST2 BST2 Q10589 Bone marrow stromal antigen 2 chr19 GO:0008284 Not Cancer Driver No 19 0.106 20 0 0.0 0
BTC BTC P35070 Probetacellulin chr4 GO:0008284 Not Cancer Driver No 29 0.163 12 5 0.417 0
CACUL1 CACUL1 Q86Y37 CDK2-associated and cullin domain-containing protein 1 chr10 GO:0008284 Not Cancer Driver No 35 0.095 128 6 0.047 0
CALCRL CALCRL Q16602 Calcitonin gene-related peptide type 1 receptor chr2 GO:0008284 Not Cancer Driver No 122 0.265 8 4 0.5 0
CALR CALR P27797 Calreticulin chr19 GO:0008284 Census Yes 45 0.108 245 31 0.127 0
CAMP CAMP P49913 Cathelicidin antimicrobial peptide chr3 GO:0008284 Not Cancer Driver No 25 0.147 48 4 0.083 0
CAPN1_ENST00000533129 CAPN1 P07384 Calpain-1 catalytic subunit chr11 GO:0008284 Not Cancer Driver No 68 0.095 32 2 0.062 1
CAPNS1 CAPNS1 P04632 Calpain small subunit 1 chr19 GO:0008284 Not Cancer Driver No 30 0.112 58 5 0.086 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:0008284 Census, Compendium Yes 303 0.263 530 140 0.264 5
CARM1 CARM1 Q86X55 Histone-arginine methyltransferase CARM1 chr19 GO:0008284 Not Cancer Driver No 62 0.102 102 10 0.098 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0008284 Not Cancer Driver No 304 0.282 189 60 0.317 108
CAV2 CAV2 P51636 Caveolin-2 chr7 GO:0008284 Not Cancer Driver No 20 0.123 5 2 0.4 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0008284 Not Cancer Driver No 27 0.179 0 0 0.0 25
CCAR1 CCAR1 Q8IX12 Cell division cycle and apoptosis regulator protein 1 chr10 GO:0008284 Not Cancer Driver No 145 0.126 771 76 0.099 0
CCDC117 CCDC117 Q8IWD4 Coiled-coil domain-containing protein 117 chr22 GO:0008284 Not Cancer Driver No 27 0.097 255 22 0.086 0
CCKBR CCKBR P32239 Gastrin/cholecystokinin type B receptor chr11 GO:0008284 Not Cancer Driver No 122 0.273 61 22 0.361 0
CCL11 CCL11 P51671 Eotaxin chr17 GO:0008284 Not Cancer Driver No 18 0.186 14 3 0.214 0
CCL24_ENST00000222902 CCL24 O00175 C-C motif chemokine 24 chr7 GO:0008284 Not Cancer Driver No 25 0.21 23 3 0.13 0
CCL26_ENST00000005180 CCL26 Q9Y258 C-C motif chemokine 26 chr7 GO:0008284 Not Cancer Driver No 9 0.096 0 0 0.0 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0008284 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0008284 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCN4 CCN4 O95388 CCN family member 4 chr8 GO:0008284 Not Cancer Driver No 93 0.253 20 8 0.4 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:0008284 Not Cancer Driver No 45 0.104 186 19 0.102 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 GO:0008284 Not Cancer Driver No 49 0.113 145 14 0.097 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0008284 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCND2 CCND2 P30279 G1/S-specific cyclin-D2 chr12 GO:0008284 Census, Compendium Yes 39 0.135 29 7 0.241 5
CCNE1 CCNE1 P24864 G1/S-specific cyclin-E1 chr19 GO:0008284 Census Yes 63 0.154 142 26 0.183 0
CCPG1_ENST00000310958 CCPG1 Q9ULG6 Cell cycle progression protein 1 chr15 GO:0008284 Not Cancer Driver No 95 0.125 509 64 0.126 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0008284 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR3_ENST00000357422 CCR3 P51677 C-C chemokine receptor type 3 chr3 GO:0008284 Not Cancer Driver No 84 0.237 0 0 0.0 0
CD248 CD248 Q9HCU0 Endosialin chr11 GO:0008284 Not Cancer Driver No 110 0.145 369 58 0.157 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0008284 Census Yes 42 0.191 18 10 0.556 0
CD320 CD320 Q9NPF0 CD320 antigen chr19 GO:0008284 Not Cancer Driver No 30 0.106 82 9 0.11 0
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0008284 Not Cancer Driver No 54 0.18 3 1 0.333 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0008284 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0008284 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0008284 Not Cancer Driver No 37 0.115 0 0 0.0 0
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0008284 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0008284 Census Yes 31 0.105 185 20 0.108 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0008284 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0008284 Not Cancer Driver No 90 0.274 56 18 0.321 0
CDC123 CDC123 O75794 Cell division cycle protein 123 homolog chr10 GO:0008284 Not Cancer Driver No 38 0.113 57 4 0.07 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0008284 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC25B CDC25B P30305 M-phase inducer phosphatase 2 chr20 GO:0008284 Not Cancer Driver No 80 0.138 328 43 0.131 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0008284 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0008284 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDC7 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 GO:0008284 Not Cancer Driver No 72 0.125 185 24 0.13 0
CDCA7L CDCA7L Q96GN5 Cell division cycle-associated 7-like protein chr7 GO:0008284 Not Cancer Driver No 83 0.183 263 48 0.183 0
CDH13_ENST00000567109 CDH13 P55290 Cadherin-13 chr16 GO:0008284 Not Cancer Driver No 168 0.236 235 59 0.251 0
CDH3 CDH3 P22223 Cadherin-3 chr16 GO:0008284 Not Cancer Driver No 87 0.105 488 52 0.107 2
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0008284 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK13 CDK13 Q14004 Cyclin-dependent kinase 13 chr7 GO:0008284 Not Cancer Driver No 155 0.103 1138 99 0.087 6
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0008284 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 GO:0008284 Census, Compendium Yes 52 0.172 52 5 0.096 3
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 GO:0008284 Census Yes 40 0.123 24 3 0.125 1
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0008284 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0008284 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDX2 CDX2 Q99626 Homeobox protein CDX-2 chr13 GO:0008284 Census, Compendium Yes 39 0.125 271 35 0.129 0
CEACAM6 CEACAM6 P40199 Carcinoembryonic antigen-related cell adhesion molecule 6 chr19 GO:0008284 Not Cancer Driver No 63 0.183 110 19 0.173 0
CEP131 CEP131 Q9UPN4 Centrosomal protein of 131 kDa chr17 GO:0008284 Not Cancer Driver No 126 0.116 948 113 0.119 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0008284 Not Cancer Driver No 40 0.083 44 2 0.045 0
CGA_ENST00000627148 CGA P01215 Glycoprotein hormones alpha chain chr6 GO:0008284 Not Cancer Driver No 28 0.241 0 0 0.0 0
CHP2 CHP2 O43745 Calcineurin B homologous protein 2 chr16 GO:0008284 Not Cancer Driver No 43 0.219 65 16 0.246 0
CHRD CHRD Q9H2X0 Chordin chr3 GO:0008284 Not Cancer Driver No 171 0.179 308 61 0.198 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0008284 Not Cancer Driver No 71 0.141 18 4 0.222 0
CHRNB2 CHRNB2 P17787 Neuronal acetylcholine receptor subunit beta-2 chr1 GO:0008284 Not Cancer Driver No 92 0.183 23 2 0.087 2
CHTOP_ENST00000368694 CHTOP Q9Y3Y2 Chromatin target of PRMT1 protein chr1 GO:0008284 Not Cancer Driver No 36 0.145 244 34 0.139 0
CIAO1 CIAO1 O76071 Probable cytosolic iron-sulfur protein assembly protein CIAO1 chr2 GO:0008284 Not Cancer Driver No 30 0.088 20 2 0.1 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0008284 Not Cancer Driver No 24 0.126 6 1 0.167 0
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0008284 Not Cancer Driver No 24 0.124 166 21 0.127 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0008284 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0008284 Not Cancer Driver No 31 0.147 16 3 0.188 0
CLDN5_ENST00000618236 CLDN5 O00501 Claudin-5 chr22 GO:0008284 Not Cancer Driver No 15 0.069 0 0 0.0 0
CLEC11A CLEC11A Q9Y240 C-type lectin domain family 11 member A chr19 GO:0008284 Not Cancer Driver No 23 0.071 184 20 0.109 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0008284 Not Cancer Driver No 43 0.174 46 2 0.043 0
CNBP_ENST00000422453 CNBP P62633 CCHC-type zinc finger nucleic acid binding protein chr3 GO:0008284 Census Yes 11 0.062 19 0 0.0 0
CNOT6L CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 GO:0008284 Not Cancer Driver No 58 0.105 37 3 0.081 0
CNOT6_ENST00000261951 CNOT6 Q9ULM6 CCR4-NOT transcription complex subunit 6 chr5 GO:0008284 Not Cancer Driver No 65 0.117 66 4 0.061 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0008284 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNOT8 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 GO:0008284 Not Cancer Driver No 30 0.103 6 0 0.0 0
CNTF CNTF P26441 Ciliary neurotrophic factor chr11 GO:0008284 Not Cancer Driver No 41 0.205 34 5 0.147 0
CNTFR_ENST00000351266 CNTFR P26992 Ciliary neurotrophic factor receptor subunit alpha chr9 GO:0008284 Not Cancer Driver No 50 0.134 92 8 0.087 0
COMP COMP P49747 Cartilage oligomeric matrix protein chr19 GO:0008284 Not Cancer Driver No 97 0.128 306 52 0.17 61
COPS9_ENST00000607357 COPS9 Q8WXC6 COP9 signalosome complex subunit 9 chr2 GO:0008284 Not Cancer Driver No 6 0.105 25 3 0.12 0
COX17_ENST00000497116 COX17 Q14061 Cytochrome c oxidase copper chaperone chr3 GO:0008284 Not Cancer Driver No 7 0.111 15 2 0.133 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0008284 Compendium Yes 383 0.188 151 42 0.278 0
CRIP2_ENST00000329146 CRIP2 P52943 Cysteine-rich protein 2 chr14 GO:0008284 Not Cancer Driver No 15 0.072 68 3 0.044 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0008284 Not Cancer Driver No 38 0.125 160 25 0.156 0
CRLF1 CRLF1 O75462 Cytokine receptor-like factor 1 chr19 GO:0008284 Not Cancer Driver No 51 0.121 101 7 0.069 14
CRLF2_ENST00000381566 CRLF2 Q9HC73 Cytokine receptor-like factor 2 chrX GO:0008284 Census Yes 54 0.146 62 3 0.048 0
CRNN CRNN Q9UBG3 Cornulin chr1 GO:0008284 Not Cancer Driver No 109 0.22 421 95 0.226 1
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0008284 Census Yes 133 0.137 124 17 0.137 20
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0008284 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0008284 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSF2RA_ENST00000381524 CSF2RA P15509 Granulocyte-macrophage colony-stimulating factor receptor subunit alpha chrX GO:0008284 Not Cancer Driver No 148 0.37 12 2 0.167 1
CSF2RB CSF2RB P32927 Cytokine receptor common subunit beta chr22 GO:0008284 Not Cancer Driver No 204 0.227 541 120 0.222 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0008284 Not Cancer Driver No 20 0.097 7 0 0.0 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 GO:0008284 Not Cancer Driver No 71 0.182 75 8 0.107 4
CSNK2A3 CSNK2A3 Q8NEV1 Casein kinase II subunit alpha 3 chr11 GO:0008284 Not Cancer Driver No 66 0.169 75 10 0.133 0
CTC1 CTC1 Q2NKJ3 CST complex subunit CTC1 chr17 GO:0008284 Not Cancer Driver No 142 0.117 103 8 0.078 9
CTF1 CTF1 Q16619 Cardiotrophin-1 chr16 GO:0008284 Not Cancer Driver No 6 0.03 90 4 0.044 0
CTHRC1 CTHRC1 Q96CG8 Collagen triple helix repeat-containing protein 1 chr8 GO:0008284 Not Cancer Driver No 31 0.128 62 5 0.081 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0008284 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0008284 Not Cancer Driver No 45 0.134 4 0 0.0 0
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0008284 Census, Compendium Yes 123 0.16 167 23 0.138 3
CUL4A CUL4A Q13619 Cullin-4A chr13 GO:0008284 Not Cancer Driver No 64 0.084 102 2 0.02 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0008284 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0008284 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0008284 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0008284 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL5 CXCL5 P42830 C-X-C motif chemokine 5 chr4 GO:0008284 Not Cancer Driver No 25 0.219 1 0 0.0 0
CXCR2 CXCR2 P25025 C-X-C chemokine receptor type 2 chr2 GO:0008284 Not Cancer Driver No 87 0.242 8 0 0.0 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0008284 Not Cancer Driver No 26 0.133 66 2 0.03 12
DBF4B DBF4B Q8NFT6 Protein DBF4 homolog B chr17 GO:0008284 Not Cancer Driver No 68 0.111 311 22 0.071 0
DCT_ENST00000377028 DCT P40126 L-dopachrome tautomerase chr13 GO:0008284 Not Cancer Driver No 113 0.218 19 4 0.211 2
DDR2 DDR2 Q16832 Discoidin domain-containing receptor 2 chr1 GO:0008284 Census Yes 192 0.225 118 34 0.288 7
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0008284 Not Cancer Driver No 34 0.108 181 23 0.127 0
DERL2 DERL2 Q9GZP9 Derlin-2 chr17 GO:0008284 Not Cancer Driver No 19 0.079 15 1 0.067 0
DHPS DHPS P49366 Deoxyhypusine synthase chr19 GO:0008284 Not Cancer Driver No 52 0.141 69 4 0.058 1
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0008284 Compendium Yes 182 0.143 331 42 0.127 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 GO:0008284 Not Cancer Driver No 132 0.155 514 82 0.16 0
DISP3 DISP3 Q9P2K9 Protein dispatched homolog 3 chr1 GO:0008284 Not Cancer Driver No 320 0.23 172 44 0.256 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0008284 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0008284 Not Cancer Driver No 115 0.159 145 24 0.166 1
DLL4 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0008284 Not Cancer Driver No 75 0.109 73 15 0.205 7
DMRTA2_ENST00000418121 DMRTA2 Q96SC8 Doublesex- and mab-3-related transcription factor A2 chr1 GO:0008284 Not Cancer Driver No 25 0.046 325 19 0.058 0
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 GO:0008284 Not Cancer Driver No 50 0.121 174 27 0.155 0
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0008284 Not Cancer Driver No 203 0.126 702 78 0.111 4
DOT1L DOT1L Q8TEK3 Histone-lysine N-methyltransferase, H3 lysine-79 specific chr19 GO:0008284 Compendium Yes 178 0.116 988 118 0.119 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0008284 Not Cancer Driver No 151 0.197 8 1 0.125 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0008284 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0008284 Not Cancer Driver No 88 0.22 45 17 0.378 0
DYNAP DYNAP Q8N1N2 Dynactin-associated protein chr18 GO:0008284 Not Cancer Driver No 54 0.257 78 21 0.269 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0008284 Not Cancer Driver No 49 0.112 272 23 0.085 0
E2F3 E2F3 O00716 Transcription factor E2F3 chr6 GO:0008284 Not Cancer Driver No 46 0.099 253 20 0.079 0
EAPP EAPP Q56P03 E2F-associated phosphoprotein chr14 GO:0008284 Not Cancer Driver No 35 0.123 210 27 0.129 0
EBI3 EBI3 Q14213 Interleukin-27 subunit beta chr19 GO:0008284 Not Cancer Driver No 32 0.14 10 1 0.1 0
ECM1_ENST00000369047 ECM1 Q16610 Extracellular matrix protein 1 chr1 GO:0008284 Not Cancer Driver No 91 0.169 219 28 0.128 1
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0008284 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDN2 EDN2 P20800 Endothelin-2 chr1 GO:0008284 Not Cancer Driver No 21 0.118 87 13 0.149 0
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 GO:0008284 Not Cancer Driver No 69 0.29 140 44 0.314 3
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0008284 Not Cancer Driver No 112 0.253 56 19 0.339 6
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 GO:0008284 Not Cancer Driver No 42 0.126 97 15 0.155 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0008284 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFL7_ENST00000308874 EGFL7 Q9UHF1 Epidermal growth factor-like protein 7 chr9 GO:0008284 Not Cancer Driver No 24 0.088 36 2 0.056 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0008284 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0008284 Not Cancer Driver No 78 0.144 501 72 0.144 0
EGR3 EGR3 Q06889 Early growth response protein 3 chr8 GO:0008284 Not Cancer Driver No 60 0.155 252 46 0.183 0
EGR4 EGR4 Q05215 Early growth response protein 4 chr2 GO:0008284 Not Cancer Driver No 56 0.095 377 27 0.072 0
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0008284 Not Cancer Driver No 39 0.146 18 3 0.167 89
ELL3 ELL3 Q9HB65 RNA polymerase II elongation factor ELL3 chr15 GO:0008284 Not Cancer Driver No 50 0.126 186 13 0.07 0
EMC10 EMC10 Q5UCC4 ER membrane protein complex subunit 10 chr19 GO:0008284 Not Cancer Driver No 25 0.095 109 15 0.138 0
EMP2_ENST00000536829 EMP2 P54851 Epithelial membrane protein 2 chr16 GO:0008284 Not Cancer Driver No 24 0.144 0 0 0.0 2
EPCAM EPCAM P16422 Epithelial cell adhesion molecule chr2 GO:0008284 Not Cancer Driver No 40 0.127 25 2 0.08 1
EPGN EPGN Q6UW88 Epigen chr4 GO:0008284 Not Cancer Driver No 16 0.104 0 0 0.0 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0008284 Not Cancer Driver No 147 0.151 211 38 0.18 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0008284 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0008284 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPO EPO P01588 Erythropoietin chr7 GO:0008284 Not Cancer Driver No 27 0.14 9 1 0.111 1
EPOR EPOR P19235 Erythropoietin receptor chr19 GO:0008284 Not Cancer Driver No 41 0.081 120 11 0.092 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0008284 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0008284 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0008284 Census, Compendium Yes 428 0.327 323 116 0.359 2
EREG EREG O14944 Proepiregulin chr4 GO:0008284 Not Cancer Driver No 26 0.154 10 3 0.3 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0008284 Not Cancer Driver No 125 0.128 250 28 0.112 0
ESM1 ESM1 Q9NQ30 Endothelial cell-specific molecule 1 chr5 GO:0008284 Not Cancer Driver No 44 0.239 37 11 0.297 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0008284 Census, Compendium Yes 121 0.203 195 27 0.138 2
EYA1_ENST00000647540 EYA1 Q99502 Eyes absent homolog 1 chr8 GO:0008284 Not Cancer Driver No 168 0.284 341 99 0.29 15
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0008284 Census, Compendium Yes 120 0.161 284 44 0.155 11
F2 F2 P00734 Prothrombin chr11 GO:0008284 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0008284 Not Cancer Driver No 73 0.172 19 2 0.105 0
F3 F3 P13726 Tissue factor chr1 GO:0008284 Not Cancer Driver No 28 0.095 61 7 0.115 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0008284 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM98A FAM98A Q8NCA5 Protein FAM98A chr2 GO:0008284 Not Cancer Driver No 63 0.122 314 36 0.115 0
FAM98B FAM98B Q52LJ0 Protein FAM98B chr15 GO:0008284 Not Cancer Driver No 34 0.079 244 9 0.037 0
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 GO:0008284 Not Cancer Driver No 65 0.231 94 18 0.191 1
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:0008284 Not Cancer Driver No 48 0.107 113 13 0.115 0
FCGR3A_ENST00000443193 FCGR3A P08637 Low affinity immunoglobulin gamma Fc region receptor III-A chr1 GO:0008284 Not Cancer Driver No 69 0.272 0 0 0.0 1
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:0008284 Not Cancer Driver No 193 0.263 217 44 0.203 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0008284 Not Cancer Driver No 114 0.139 145 21 0.145 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0008284 Not Cancer Driver No 71 0.104 101 10 0.099 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0008284 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF16 FGF16 O43320 Fibroblast growth factor 16 chrX GO:0008284 Not Cancer Driver No 29 0.14 28 6 0.214 1
FGF17 FGF17 O60258 Fibroblast growth factor 17 chr8 GO:0008284 Not Cancer Driver No 30 0.139 107 16 0.15 3
FGF18 FGF18 O76093 Fibroblast growth factor 18 chr5 GO:0008284 Not Cancer Driver No 40 0.193 57 14 0.246 0
FGF19 FGF19 O95750 Fibroblast growth factor 19 chr11 GO:0008284 Not Cancer Driver No 20 0.093 36 7 0.194 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0008284 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGF20 FGF20 Q9NP95 Fibroblast growth factor 20 chr8 GO:0008284 Not Cancer Driver No 25 0.118 57 3 0.053 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0008284 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF22 FGF22 Q9HCT0 Fibroblast growth factor 22 chr19 GO:0008284 Not Cancer Driver No 15 0.088 42 3 0.071 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0008284 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0008284 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGF3 FGF3 P11487 Fibroblast growth factor 3 chr11 GO:0008284 Not Cancer Driver No 40 0.167 104 24 0.231 2
FGF4 FGF4 P08620 Fibroblast growth factor 4 chr11 GO:0008284 Not Cancer Driver No 16 0.078 21 3 0.143 0
FGF5 FGF5 P12034 Fibroblast growth factor 5 chr4 GO:0008284 Not Cancer Driver No 64 0.239 129 30 0.233 1
FGF6 FGF6 P10767 Fibroblast growth factor 6 chr12 GO:0008284 Not Cancer Driver No 65 0.312 0 0 0.0 0
FGF7 FGF7 P21781 Fibroblast growth factor 7 chr15 GO:0008284 Not Cancer Driver No 38 0.196 22 4 0.182 0
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0008284 Not Cancer Driver No 30 0.129 79 9 0.114 6
FGF9 FGF9 P31371 Fibroblast growth factor 9 chr13 GO:0008284 Not Cancer Driver No 41 0.197 43 10 0.233 1
FGFBP1 FGFBP1 Q14512 Fibroblast growth factor-binding protein 1 chr4 GO:0008284 Not Cancer Driver No 28 0.12 81 8 0.099 0
FGFR1OP CEP43 O95684 Centrosomal protein 43 chr6 GO:0008284 Not Cancer Driver No 43 0.108 272 33 0.121 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0008284 Census, Compendium Yes 152 0.185 230 43 0.187 74
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0008284 Census, Compendium Yes 238 0.29 228 44 0.193 72
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 GO:0008284 Census, Compendium Yes 173 0.215 241 26 0.108 37
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:0008284 Census, Compendium Yes 113 0.141 162 28 0.173 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0008284 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0008284 Census, Compendium Yes 200 0.201 64 27 0.422 0
FLT3LG_ENST00000600429 FLT3LG P49771 Fms-related tyrosine kinase 3 ligand chr19 GO:0008284 Not Cancer Driver No 27 0.115 39 4 0.103 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0008284 Census, Compendium Yes 253 0.186 259 41 0.158 13
FN1 FN1 P02751 Fibronectin chr2 GO:0008284 Compendium Yes 394 0.159 1243 185 0.149 8
FOLR2 FOLR2 P14207 Folate receptor beta chr11 GO:0008284 Not Cancer Driver No 32 0.125 6 0 0.0 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0008284 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOSL2 FOSL2 P15408 Fos-related antigen 2 chr2 GO:0008284 Not Cancer Driver No 54 0.166 323 54 0.167 0
FOXE3 FOXE3 Q13461 Forkhead box protein E3 chr1 GO:0008284 Not Cancer Driver No 12 0.038 186 4 0.022 6
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0008284 Not Cancer Driver No 56 0.148 194 20 0.103 20
FOXG1 FOXG1 P55316 Forkhead box protein G1 chr14 GO:0008284 Not Cancer Driver No 132 0.27 322 79 0.245 2
FOXJ2 FOXJ2 Q9P0K8 Forkhead box protein J2 chr12 GO:0008284 Not Cancer Driver No 81 0.141 483 65 0.135 0
FOXM1_ENST00000359843 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:0008284 Not Cancer Driver No 97 0.127 601 73 0.121 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0008284 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0008284 Not Cancer Driver No 38 0.088 186 16 0.086 10
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0008284 Not Cancer Driver No 69 0.136 415 58 0.14 0
FSHB_ENST00000254122 FSHB P01225 Follitropin subunit beta chr11 GO:0008284 Not Cancer Driver No 31 0.24 0 0 0.0 1
FTMT FTMT Q8N4E7 Ferritin, mitochondrial chr5 GO:0008284 Not Cancer Driver No 96 0.397 93 33 0.355 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0008284 Not Cancer Driver No 16 0.076 73 0 0.0 8
FZD3_ENST00000240093 FZD3 Q9NPG1 Frizzled-3 chr8 GO:0008284 Not Cancer Driver No 64 0.096 141 13 0.092 0
FZD7 FZD7 O75084 Frizzled-7 chr2 GO:0008284 Not Cancer Driver No 90 0.157 22 2 0.091 0
FZD9 FZD9 O00144 Frizzled-9 chr7 GO:0008284 Not Cancer Driver No 55 0.093 61 0 0.0 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0008284 Not Cancer Driver No 74 0.149 184 30 0.163 0
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 GO:0008284 Not Cancer Driver No 85 0.126 537 73 0.136 0
GAREM1 GAREM1 Q9H706 GRB2-associated and regulator of MAPK protein 1 chr18 GO:0008284 Not Cancer Driver No 128 0.146 408 50 0.123 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0008284 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0008284 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0008284 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0008284 Not Cancer Driver No 57 0.096 476 51 0.107 10
GCNT2_ENST00000379597 GCNT2 Q8N0V5 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase chr6 GO:0008284 Not Cancer Driver No 40 0.1 3 0 0.0 0
GDF9 GDF9 O60383 Growth/differentiation factor 9 chr5 GO:0008284 Not Cancer Driver No 72 0.159 53 15 0.283 0
GDNF_ENST00000326524 GDNF P39905 Glial cell line-derived neurotrophic factor chr5 GO:0008284 Not Cancer Driver No 47 0.223 83 18 0.217 2
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0008284 Not Cancer Driver No 65 0.15 288 42 0.146 62
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0008284 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHRH_ENST00000237527 GHRH P01286 Somatoliberin chr20 GO:0008284 Not Cancer Driver No 13 0.12 36 4 0.111 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0008284 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0008284 Not Cancer Driver No 85 0.232 4 0 0.0 2
GID8 GID8 Q9NWU2 Glucose-induced degradation protein 8 homolog chr20 GO:0008284 Not Cancer Driver No 30 0.132 60 6 0.1 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0008284 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJC2 GJC2 Q5T442 Gap junction gamma-2 protein chr1 GO:0008284 Not Cancer Driver No 33 0.075 225 10 0.044 6
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 GO:0008284 Census, Compendium Yes 206 0.186 1015 184 0.181 0
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0008284 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLP2R GLP2R O95838 Glucagon-like peptide 2 receptor chr17 GO:0008284 Not Cancer Driver No 124 0.224 63 14 0.222 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0008284 Compendium Yes 50 0.141 24 0 0.0 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 GO:0008284 Not Cancer Driver No 42 0.119 11 0 0.0 1
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 GO:0008284 Not Cancer Driver No 108 0.13 83 7 0.084 0
GPBAR1_ENST00000521462 GPBAR1 Q8TDU6 G-protein coupled bile acid receptor 1 chr2 GO:0008284 Not Cancer Driver No 30 0.091 22 4 0.182 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0008284 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPR183 GPR183 P32249 G-protein coupled receptor 183 chr13 GO:0008284 Not Cancer Driver No 53 0.147 25 3 0.12 0
GPR37L1 GPR37L1 O60883 G-protein coupled receptor 37-like 1 chr1 GO:0008284 Not Cancer Driver No 62 0.129 81 8 0.099 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0008284 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRK5 GRK5 P34947 G protein-coupled receptor kinase 5 chr10 GO:0008284 Not Cancer Driver No 77 0.131 103 18 0.175 0
HAPLN3_ENST00000359595 HAPLN3 Q96S86 Hyaluronan and proteoglycan link protein 3 chr15 GO:0008284 Not Cancer Driver No 61 0.169 31 5 0.161 0
HAS2 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0008284 Not Cancer Driver No 100 0.181 17 7 0.412 0
HBEGF HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:0008284 Not Cancer Driver No 16 0.077 63 3 0.048 0
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0008284 Not Cancer Driver No 112 0.213 124 25 0.202 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0008284 Not Cancer Driver No 103 0.212 446 94 0.211 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0008284 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0008284 Not Cancer Driver No 46 0.094 145 14 0.097 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 GO:0008284 Not Cancer Driver No 182 0.168 749 132 0.176 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0008284 Not Cancer Driver No 37 0.132 226 32 0.142 0
HES5 HES5 Q5TA89 Transcription factor HES-5 chr1 GO:0008284 Not Cancer Driver No 1 0.006 73 0 0.0 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0008284 Not Cancer Driver No 64 0.19 179 26 0.145 0
HHLA2_ENST00000489514 HHLA2 Q9UM44 HERV-H LTR-associating protein 2 chr3 GO:0008284 Not Cancer Driver No 85 0.205 57 10 0.175 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0008284 Census Yes 118 0.143 435 51 0.117 0
HILPDA HILPDA Q9Y5L2 Hypoxia-inducible lipid droplet-associated protein chr7 GO:0008284 Not Cancer Driver No 5 0.079 33 3 0.091 0
HIPK1_ENST00000426820 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 GO:0008284 Not Cancer Driver No 158 0.131 565 89 0.158 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0008284 Not Cancer Driver No 154 0.129 686 96 0.14 0
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0008284 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0008284 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0008284 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0008284 Census Yes 12 0.11 109 12 0.11 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0008284 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0008284 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMGN5 HMGN5 P82970 High mobility group nucleosome-binding domain-containing protein 5 chrX GO:0008284 Not Cancer Driver No 27 0.096 282 27 0.096 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0008284 Not Cancer Driver No 46 0.16 81 13 0.16 0
HMX2 HMX2 A2RU54 Homeobox protein HMX2 chr10 GO:0008284 Not Cancer Driver No 36 0.132 169 21 0.124 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0008284 Not Cancer Driver No 77 0.093 504 45 0.089 0
HOXA3_ENST00000396352 HOXA3 O43365 Homeobox protein Hox-A3 chr7 GO:0008284 Not Cancer Driver No 86 0.194 417 84 0.201 0
HOXC10 HOXC10 Q9NYD6 Homeobox protein Hox-C10 chr12 GO:0008284 Not Cancer Driver No 62 0.181 266 48 0.18 0
HPGD HPGD P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] chr4 GO:0008284 Not Cancer Driver No 32 0.12 4 1 0.25 2
HPN_ENST00000392226 HPN P05981 Serine protease hepsin chr19 GO:0008284 Not Cancer Driver No 60 0.144 12 0 0.0 0
HPSE HPSE Q9Y251 Heparanase chr4 GO:0008284 Not Cancer Driver No 90 0.166 16 2 0.125 0
HPSE2 HPSE2 Q8WWQ2 Inactive heparanase-2 chr10 GO:0008284 Not Cancer Driver No 123 0.208 42 20 0.476 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0008284 Census, Compendium Yes 107 0.566 16 4 0.25 18
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0008284 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSF4 HSF4 Q9ULV5 Heat shock factor protein 4 chr16 GO:0008284 Not Cancer Driver No 37 0.075 327 25 0.076 4
HTR1A HTR1A P08908 5-hydroxytryptamine receptor 1A chr5 GO:0008284 Not Cancer Driver No 170 0.403 100 49 0.49 0
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 GO:0008284 Not Cancer Driver No 91 0.233 33 15 0.455 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0008284 Not Cancer Driver No 105 0.223 44 8 0.182 0
HTR2B HTR2B P41595 5-hydroxytryptamine receptor 2B chr2 GO:0008284 Not Cancer Driver No 41 0.085 23 2 0.087 0
ICOSLG_ENST00000407780 ICOSLG O75144 ICOS ligand chr21 GO:0008284 Not Cancer Driver No 25 0.083 30 2 0.067 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0008284 Not Cancer Driver No 14 0.104 52 7 0.135 0
ID4 ID4 P47928 DNA-binding protein inhibitor ID-4 chr6 GO:0008284 Not Cancer Driver No 4 0.025 71 1 0.014 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0008284 Not Cancer Driver No 51 0.307 23 6 0.261 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0008284 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0008284 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0008284 Not Cancer Driver No 39 0.217 44 12 0.273 0
IGFBP2 IGFBP2 P18065 Insulin-like growth factor-binding protein 2 chr2 GO:0008284 Not Cancer Driver No 32 0.098 171 24 0.14 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0008284 Not Cancer Driver No 27 0.099 112 17 0.152 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0008284 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0008284 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL11 IL11 P20809 Interleukin-11 chr19 GO:0008284 Not Cancer Driver No 19 0.095 69 8 0.116 0
IL11RA_ENST00000441545 IL11RA Q14626 Interleukin-11 receptor subunit alpha chr9 GO:0008284 Not Cancer Driver No 48 0.114 153 11 0.072 3
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0008284 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0008284 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL12RB2 IL12RB2 Q99665 Interleukin-12 receptor subunit beta-2 chr1 GO:0008284 Not Cancer Driver No 129 0.15 195 31 0.159 0
IL13 IL13 P35225 Interleukin-13 chr5 GO:0008284 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL13RA1 IL13RA1 P78552 Interleukin-13 receptor subunit alpha-1 chrX GO:0008284 Not Cancer Driver No 58 0.136 33 7 0.212 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0008284 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0008284 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0008284 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0008284 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0008284 Census Yes 24 0.157 6 1 0.167 0
IL21 IL21 Q9HBE4 Interleukin-21 chr4 GO:0008284 Not Cancer Driver No 34 0.21 70 18 0.257 1
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0008284 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0008284 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL24_ENST00000294984 IL24 Q13007 Interleukin-24 chr1 GO:0008284 Not Cancer Driver No 35 0.17 0 0 0.0 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0008284 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL2RA IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 GO:0008284 Not Cancer Driver No 51 0.188 131 29 0.221 2
IL3 IL3 P08700 Interleukin-3 chr5 GO:0008284 Not Cancer Driver No 25 0.164 22 3 0.136 0
IL31RA_ENST00000297015 IL31RA Q8NI17 Interleukin-31 receptor subunit alpha chr5 GO:0008284 Not Cancer Driver No 117 0.16 163 30 0.184 1
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0008284 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0008284 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL5 IL5 P05113 Interleukin-5 chr5 GO:0008284 Not Cancer Driver No 13 0.097 0 0 0.0 0
IL5RA_ENST00000256452 IL5RA Q01344 Interleukin-5 receptor subunit alpha chr3 GO:0008284 Not Cancer Driver No 92 0.219 23 5 0.217 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0008284 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0008284 Not Cancer Driver No 55 0.118 165 23 0.139 1
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0008284 Census, Compendium Yes 102 0.111 315 40 0.127 2
IL7 IL7 P13232 Interleukin-7 chr8 GO:0008284 Not Cancer Driver No 29 0.164 19 4 0.211 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0008284 Census, Compendium Yes 177 0.386 88 48 0.545 1
IL9 IL9 P15248 Interleukin-9 chr5 GO:0008284 Not Cancer Driver No 12 0.083 4 0 0.0 0
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 GO:0008284 Not Cancer Driver No 45 0.1 71 9 0.127 0
INS INS P01308 Insulin chr11 GO:0008284 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSL3_ENST00000317306 INSL3 P51460 Insulin-like 3 chr19 GO:0008284 Not Cancer Driver No 18 0.137 34 12 0.353 3
INSL4 INSL4 Q14641 Early placenta insulin-like peptide chr9 GO:0008284 Not Cancer Driver No 31 0.223 52 12 0.231 0
INSM1 INSM1 Q01101 Insulinoma-associated protein 1 chr20 GO:0008284 Not Cancer Driver No 25 0.049 359 12 0.033 0
INSR INSR P06213 Insulin receptor chr19 GO:0008284 Not Cancer Driver No 190 0.137 280 57 0.204 64
IQGAP3 IQGAP3 Q86VI3 Ras GTPase-activating-like protein IQGAP3 chr1 GO:0008284 Not Cancer Driver No 233 0.143 257 36 0.14 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0008284 Compendium Yes 71 0.1 337 39 0.116 0
IRAK4_ENST00000551736 IRAK4 Q9NWZ3 Interleukin-1 receptor-associated kinase 4 chr12 GO:0008284 Not Cancer Driver No 68 0.148 116 20 0.172 2
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0008284 Not Cancer Driver No 161 0.13 1072 133 0.124 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0008284 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0008284 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0008284 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0008284 Not Cancer Driver No 254 0.246 97 27 0.278 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0008284 Census Yes 153 0.146 92 9 0.098 0
ITGAX_ENST00000268296 ITGAX P20702 Integrin alpha-X chr16 GO:0008284 Not Cancer Driver No 245 0.211 82 15 0.183 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0008284 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0008284 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0008284 Not Cancer Driver No 124 0.157 66 5 0.076 30
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0008284 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0008284 Census, Compendium Yes 167 0.149 63 10 0.159 7
JAML JAML Q86YT9 Junctional adhesion molecule-like chr11 GO:0008284 Not Cancer Driver No 72 0.183 68 11 0.162 0
JCAD JCAD Q9P266 Junctional protein associated with coronary artery disease chr10 GO:0008284 Not Cancer Driver No 291 0.214 1337 290 0.217 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0008284 Census Yes 35 0.106 281 25 0.089 0
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:0008284 Census Yes 97 0.159 327 47 0.144 0
KCNA5 KCNA5 P22460 Potassium voltage-gated channel subfamily A member 5 chr12 GO:0008284 Not Cancer Driver No 213 0.347 218 53 0.243 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0008284 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM4C KDM4C Q9H3R0 Lysine-specific demethylase 4C chr9 GO:0008284 Not Cancer Driver No 124 0.117 309 40 0.129 0
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 GO:0008284 Not Cancer Driver No 219 0.142 388 58 0.149 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0008284 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 GO:0008284 Not Cancer Driver No 222 0.135 774 102 0.132 2
KIF20B KIF20B Q96Q89 Kinesin-like protein KIF20B chr10 GO:0008284 Not Cancer Driver No 217 0.119 902 109 0.121 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0008284 Census, Compendium Yes 226 0.232 83 33 0.398 21
KITLG KITLG P21583 Kit ligand chr12 GO:0008284 Not Cancer Driver No 48 0.176 61 9 0.148 1
KLB KLB Q86Z14 Beta-klotho chr4 GO:0008284 Not Cancer Driver No 139 0.133 6 1 0.167 0
KMT2D KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 GO:0008284 Census, Compendium Yes 773 0.14 4386 552 0.126 13
KRAS KRAS P01116 GTPase KRas chr12 GO:0008284 Census, Compendium Yes 788 4.169 7 2 0.286 27
KRT6A KRT6A P02538 Keratin, type II cytoskeletal 6A chr12 GO:0008284 Not Cancer Driver No 127 0.225 138 35 0.254 24
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:0008284 Not Cancer Driver No 38 0.275 90 27 0.3 0
LAMC2 LAMC2 Q13753 Laminin subunit gamma-2 chr1 GO:0008284 Not Cancer Driver No 165 0.138 496 68 0.137 0
LBH LBH Q53QV2 Protein LBH chr2 GO:0008284 Not Cancer Driver No 15 0.143 72 10 0.139 0
LDLRAP1 LDLRAP1 Q5SW96 Low density lipoprotein receptor adapter protein 1 chr1 GO:0008284 Not Cancer Driver No 36 0.117 119 17 0.143 1
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0008284 Census Yes 64 0.16 370 57 0.154 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0008284 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0008284 Not Cancer Driver No 57 0.132 112 19 0.17 0
LHX2 LHX2 P50458 LIM/homeobox protein Lhx2 chr9 GO:0008284 Not Cancer Driver No 60 0.148 203 28 0.138 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0008284 Not Cancer Driver No 25 0.124 0 0 0.0 0
LIFR_ENST00000453190 LIFR P42702 Leukemia inhibitory factor receptor chr5 GO:0008284 Census, Compendium Yes 247 0.225 259 56 0.216 1
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0008284 Not Cancer Driver No 134 0.147 63 10 0.159 2
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0008284 Not Cancer Driver No 37 0.177 86 12 0.14 0
LRG1 LRG1 P02750 Leucine-rich alpha-2-glycoprotein chr19 GO:0008284 Not Cancer Driver No 63 0.182 29 8 0.276 0
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0008284 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRP5 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 GO:0008284 Not Cancer Driver No 253 0.157 188 28 0.149 55
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0008284 Not Cancer Driver No 37 0.18 20 5 0.25 0
LTBP3 LTBP3 Q9NS15 Latent-transforming growth factor beta-binding protein 3 chr11 GO:0008284 Not Cancer Driver No 108 0.083 356 22 0.062 0
LTF LTF P02788 Lactotransferrin chr3 GO:0008284 Not Cancer Driver No 131 0.185 21 4 0.19 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0008284 Census Yes 95 0.186 84 12 0.143 0
MAB21L1 MAB21L1 Q13394 Putative nucleotidyltransferase MAB21L1 chr13 GO:0008284 Not Cancer Driver No 94 0.262 0 0 0.0 0
MAB21L2 MAB21L2 Q9Y586 Protein mab-21-like 2 chr4 GO:0008284 Not Cancer Driver No 81 0.226 6 3 0.5 5
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 GO:0008284 Not Cancer Driver No 74 0.118 355 44 0.124 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0008284 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0008284 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0008284 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0008284 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0008284 Not Cancer Driver No 38 0.1 49 5 0.102 0
MARCH7 MARCHF7 Q9H992 E3 ubiquitin-protein ligase MARCHF7 chr2 GO:0008284 Not Cancer Driver No 85 0.121 550 68 0.124 0
MARCKSL1 MARCKSL1 P49006 MARCKS-related protein chr1 GO:0008284 Not Cancer Driver No 28 0.144 195 28 0.144 0
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 GO:0008284 Not Cancer Driver No 47 0.145 5 2 0.4 0
MATK_ENST00000310132 MATK P42679 Megakaryocyte-associated tyrosine-protein kinase chr19 GO:0008284 Not Cancer Driver No 94 0.185 146 27 0.185 0
MAZ_ENST00000322945 MAZ P56270 Myc-associated zinc finger protein chr16 GO:0008284 Not Cancer Driver No 46 0.096 249 22 0.088 0
MCTS1_ENST00000371317 MCTS1 Q9ULC4 Malignant T-cell-amplified sequence 1 chrX GO:0008284 Not Cancer Driver No 34 0.188 0 0 0.0 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0008284 Not Cancer Driver No 15 0.105 20 2 0.1 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0008284 Census, Compendium Yes 56 0.114 297 37 0.125 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0008284 Not Cancer Driver No 75 0.154 483 74 0.153 46
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0008284 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0008284 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEF2D MEF2D Q14814 Myocyte-specific enhancer factor 2D chr1 GO:0008284 Not Cancer Driver No 72 0.138 455 67 0.147 0
MEGF10_ENST00000503335 MEGF10 Q96KG7 Multiple epidermal growth factor-like domains protein 10 chr5 GO:0008284 Not Cancer Driver No 216 0.189 204 42 0.206 2
MEIS1 MEIS1 O00470 Homeobox protein Meis1 chr2 GO:0008284 Not Cancer Driver No 89 0.228 267 62 0.232 0
MEIS2 MEIS2 O14770 Homeobox protein Meis2 chr15 GO:0008284 Not Cancer Driver No 94 0.197 358 76 0.212 0
MEIS3_ENST00000558555 MEIS3 Q99687 Homeobox protein Meis3 chr19 GO:0008284 Not Cancer Driver No 54 0.144 247 43 0.174 0
MFN2_ENST00000444836 MFN2 O95140 Mitofusin-2 chr1 GO:0008284 Not Cancer Driver No 80 0.106 81 9 0.111 20
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0008284 Not Cancer Driver No 4 0.035 0 0 0.0 0
MLXIPL MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0008284 Not Cancer Driver No 106 0.124 554 66 0.119 0
MMP12 MMP12 P39900 Macrophage metalloelastase chr11 GO:0008284 Not Cancer Driver No 100 0.213 29 5 0.172 0
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0008284 Not Cancer Driver No 123 0.186 29 6 0.207 2
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0008284 Not Cancer Driver No 129 0.182 124 26 0.21 0
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:0008284 Not Cancer Driver No 23 0.074 64 2 0.031 0
MPL MPL P40238 Thrombopoietin receptor chr1 GO:0008284 Census Yes 77 0.121 129 19 0.147 14
MST1R MST1R Q04912 Macrophage-stimulating protein receptor chr3 GO:0008284 Not Cancer Driver No 178 0.127 182 27 0.148 1
MTA3 MTA3 Q9BTC8 Metastasis-associated protein MTA3 chr2 GO:0008284 Not Cancer Driver No 48 0.081 169 18 0.107 0
MVD MVD P53602 Diphosphomevalonate decarboxylase chr16 GO:0008284 Not Cancer Driver No 47 0.117 49 10 0.204 3
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0008284 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0008284 Census, Compendium Yes 37 0.125 47 1 0.021 2
MYDGF MYDGF Q969H8 Myeloid-derived growth factor chr19 GO:0008284 Not Cancer Driver No 23 0.133 26 4 0.154 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0008284 Not Cancer Driver No 284 0.303 853 263 0.308 0
MZB1 MZB1 Q8WU39 Marginal zone B- and B1-cell-specific protein chr5 GO:0008284 Not Cancer Driver No 15 0.079 75 9 0.12 0
N4BP2L2_ENST00000267068 N4BP2L2 Q92802 NEDD4-binding protein 2-like 2 chr13 GO:0008284 Not Cancer Driver No 81 0.139 373 55 0.147 0
NACC1 NACC1 Q96RE7 Nucleus accumbens-associated protein 1 chr19 GO:0008284 Not Cancer Driver No 51 0.097 282 24 0.085 1
NAMPT NAMPT P43490 Nicotinamide phosphoribosyltransferase chr7 GO:0008284 Not Cancer Driver No 50 0.102 27 5 0.185 0
NANOG NANOG Q9H9S0 Homeobox protein NANOG chr12 GO:0008284 Not Cancer Driver No 46 0.151 169 35 0.207 0
NANOGP8 NANOGP8 Q6NSW7 Homeobox protein NANOGP8 chr15 GO:0008284 Not Cancer Driver No 4 0.013 176 4 0.023 0
NAP1L1 NAP1L1 P55209 Nucleosome assembly protein 1-like 1 chr12 GO:0008284 Not Cancer Driver No 47 0.12 207 31 0.15 0
NCCRP1 NCCRP1 Q6ZVX7 F-box only protein 50 chr19 GO:0008284 Not Cancer Driver No 38 0.138 139 22 0.158 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0008284 Not Cancer Driver No 247 0.219 51 10 0.196 4
NDUFAF4 NDUFAF4 Q9P032 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 chr6 GO:0008284 Not Cancer Driver No 14 0.08 46 4 0.087 2
NDUFS4 NDUFS4 O43181 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial chr5 GO:0008284 Not Cancer Driver No 26 0.149 92 17 0.185 1
NES NES P48681 Nestin chr1 GO:0008284 Not Cancer Driver No 271 0.167 1474 253 0.172 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0008284 Census, Compendium Yes 375 0.132 406 47 0.116 85
NFATC2 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 GO:0008284 Census, Compendium Yes 194 0.21 722 162 0.224 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0008284 Not Cancer Driver No 57 0.133 172 25 0.145 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0008284 Not Cancer Driver No 48 0.148 181 22 0.122 55
NKX2-6 NKX2-6 A6NCS4 Homeobox protein Nkx-2.6 chr8 GO:0008284 Not Cancer Driver No 10 0.033 243 7 0.029 3
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0008284 Not Cancer Driver No 35 0.15 171 16 0.094 0
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0008284 Not Cancer Driver No 91 0.109 300 19 0.063 0
NMB_ENST00000360476 NMB P08949 Neuromedin-B chr15 GO:0008284 Not Cancer Driver No 6 0.05 30 2 0.067 0
NOLC1_ENST00000605788 NOLC1 Q14978 Nucleolar and coiled-body phosphoprotein 1 chr10 GO:0008284 Not Cancer Driver No 74 0.106 662 69 0.104 0
NOP2_ENST00000322166 NOP2 P46087 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase chr12 GO:0008284 Not Cancer Driver No 116 0.143 510 72 0.141 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0008284 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0008284 Census, Compendium Yes 282 0.114 630 77 0.122 1
NOTCH3 NOTCH3 Q9UM47 Neurogenic locus notch homolog protein 3 chr19 GO:0008284 Not Cancer Driver No 306 0.132 557 81 0.145 110
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0008284 Not Cancer Driver No 101 0.179 18 8 0.444 0
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:0008284 Census, Compendium Yes 29 0.099 249 22 0.088 0
NPY5R_ENST00000506953 NPY5R Q15761 Neuropeptide Y receptor type 5 chr4 GO:0008284 Not Cancer Driver No 144 0.324 44 16 0.364 0
NPY_ENST00000405982 NPY P01303 Pro-neuropeptide Y chr7 GO:0008284 Not Cancer Driver No 29 0.299 43 19 0.442 0
NR2E1_ENST00000368986 NR2E1 Q9Y466 Nuclear receptor subfamily 2 group E member 1 chr6 GO:0008284 Not Cancer Driver No 75 0.195 57 6 0.105 0
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 GO:0008284 Not Cancer Driver No 62 0.104 252 24 0.095 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0008284 Census Yes 83 0.133 298 37 0.124 0
NRARP NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 GO:0008284 Not Cancer Driver No 9 0.079 11 1 0.091 0
NRAS NRAS P01111 GTPase NRas chr1 GO:0008284 Census, Compendium Yes 284 1.503 10 0 0.0 14
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0008284 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0008284 Compendium Yes 146 0.158 211 31 0.147 0
NRP2 NRP2 O60462 Neuropilin-2 chr2 GO:0008284 Not Cancer Driver No 161 0.173 207 45 0.217 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0008284 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTN1 NTN1 O95631 Netrin-1 chr17 GO:0008284 Not Cancer Driver No 57 0.094 66 4 0.061 2
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0008284 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0008284 Census, Compendium Yes 249 0.297 57 21 0.368 0
OCSTAMP OCSTAMP Q9BR26 Osteoclast stimulatory transmembrane protein chr20 GO:0008284 Not Cancer Driver No 22 0.039 52 6 0.115 0
ODAM ODAM A1E959 Odontogenic ameloblast-associated protein chr4 GO:0008284 Not Cancer Driver No 51 0.183 140 18 0.129 0
ODC1_ENST00000405333 ODC1 P11926 Ornithine decarboxylase chr2 GO:0008284 Not Cancer Driver No 46 0.1 33 7 0.212 0
OSM OSM P13725 Oncostatin-M chr22 GO:0008284 Not Cancer Driver No 43 0.171 114 24 0.211 0
OSMR OSMR Q99650 Oncostatin-M-specific receptor subunit beta chr5 GO:0008284 Not Cancer Driver No 167 0.171 145 22 0.152 5
OSR2_ENST00000522510 OSR2 Q8N2R0 Protein odd-skipped-related 2 chr8 GO:0008284 Not Cancer Driver No 59 0.189 66 13 0.197 0
OTP OTP Q5XKR4 Homeobox protein orthopedia chr5 GO:0008284 Not Cancer Driver No 36 0.111 278 29 0.104 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0008284 Not Cancer Driver No 50 0.152 10 5 0.5 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0008284 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0008284 Not Cancer Driver No 72 0.171 337 56 0.166 38
PAXBP1 PAXBP1 Q9Y5B6 PAX3- and PAX7-binding protein 1 chr21 GO:0008284 Not Cancer Driver No 96 0.105 532 55 0.103 0
PBX1 PBX1 P40424 Pre-B-cell leukemia transcription factor 1 chr1 GO:0008284 Census Yes 82 0.191 290 57 0.197 0
PBXIP1 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 GO:0008284 Not Cancer Driver No 100 0.137 605 86 0.142 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0008284 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDCD2 PDCD2 Q16342 Programmed cell death protein 2 chr6 GO:0008284 Not Cancer Driver No 32 0.093 42 6 0.143 0
PDCD6 PDCD6 O75340 Programmed cell death protein 6 chr5 GO:0008284 Not Cancer Driver No 21 0.11 24 1 0.042 0
PDCL3 PDCL3 Q9H2J4 Phosducin-like protein 3 chr2 GO:0008284 Not Cancer Driver No 48 0.201 73 13 0.178 0
PDF PDF Q9HBH1 Peptide deformylase, mitochondrial chr16 GO:0008284 Not Cancer Driver No 7 0.029 8 0 0.0 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0008284 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0008284 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0008284 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0008284 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0008284 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0008284 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0008284 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0008284 Not Cancer Driver No 32 0.113 238 23 0.097 0
PELI1 PELI1 Q96FA3 E3 ubiquitin-protein ligase pellino homolog 1 chr2 GO:0008284 Not Cancer Driver No 47 0.112 167 17 0.102 0
PGF_ENST00000405431 PGF P49763 Placenta growth factor chr14 GO:0008284 Not Cancer Driver No 30 0.136 72 10 0.139 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0008284 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHIP PHIP Q8WWQ0 PH-interacting protein chr6 GO:0008284 Not Cancer Driver No 239 0.131 835 110 0.132 0
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0008284 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0008284 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0008284 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIM1 PIM1 P11309 Serine/threonine-protein kinase pim-1 chr6 GO:0008284 Census, Compendium Yes 71 0.227 27 8 0.296 0
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0008284 Not Cancer Driver No 24 0.079 155 12 0.077 1
PKHD1 PKHD1 P08F94 Fibrocystin chr6 GO:0008284 Not Cancer Driver No 778 0.191 413 81 0.196 93
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0008284 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLAC8_ENST00000505406 PLAC8 Q9NZF1 Placenta-specific gene 8 protein chr4 GO:0008284 Not Cancer Driver No 20 0.174 7 0 0.0 0
PLAG1_ENST00000429357 PLAG1 Q6DJT9 Zinc finger protein PLAG1 chr8 GO:0008284 Census, Compendium Yes 108 0.216 209 48 0.23 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0008284 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLXNB3_ENST00000361971 PLXNB3 Q9ULL4 Plexin-B3 chrX GO:0008284 Not Cancer Driver No 217 0.114 358 37 0.103 0
PML PML P29590 Protein PML chr15 GO:0008284 Census, Compendium Yes 112 0.127 312 34 0.109 0
POU3F2 POU3F2 P20265 POU domain, class 3, transcription factor 2 chr6 GO:0008284 Not Cancer Driver No 52 0.117 361 36 0.1 0
POU3F3 POU3F3 P20264 POU domain, class 3, transcription factor 3 chr2 GO:0008284 Not Cancer Driver No 43 0.086 402 30 0.075 4
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0008284 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 GO:0008284 Not Cancer Driver No 26 0.08 23 4 0.174 0
PPP1R16B PPP1R16B Q96T49 Protein phosphatase 1 regulatory inhibitor subunit 16B chr20 GO:0008284 Not Cancer Driver No 132 0.233 220 66 0.3 0
PRAMEF1 PRAMEF1 O95521 PRAME family member 1 chr1 GO:0008284 Not Cancer Driver No 142 0.3 7 0 0.0 0
PRAMEF10 PRAMEF10 O60809 PRAME family member 10 chr1 GO:0008284 Not Cancer Driver No 91 0.192 7 1 0.143 0
PRAMEF11 PRAMEF11 O60813 PRAME family member 11 chr1 GO:0008284 Not Cancer Driver No 158 0.331 4 0 0.0 0
PRAMEF12 PRAMEF12 O95522 PRAME family member 12 chr1 GO:0008284 Not Cancer Driver No 122 0.253 6 6 1.0 0
PRAMEF14 PRAMEF14 Q5SWL7 PRAME family member 14 chr1 GO:0008284 Not Cancer Driver No 31 0.065 6 0 0.0 0
PRAMEF17 PRAMEF17 Q5VTA0 PRAME family member 17 chr1 GO:0008284 Not Cancer Driver No 34 0.072 10 3 0.3 0
PRAMEF2 PRAMEF2 O60811 PRAME family member 2 chr1 GO:0008284 Not Cancer Driver No 142 0.3 5 0 0.0 0
PRAMEF20 PRAMEF20 Q5VT98 PRAME family member 20 chr1 GO:0008284 Not Cancer Driver No 29 0.061 0 0 0.0 0
PRAMEF25 PRAMEF25 A6NGN4 PRAME family member 25 chr1 GO:0008284 Not Cancer Driver No 1 0.002 4 0 0.0 0
PRAMEF4 PRAMEF4 O60810 PRAME family member 4 chr1 GO:0008284 Not Cancer Driver No 135 0.282 4 3 0.75 0
PRAMEF5 PRAMEF5 Q5TYX0 PRAME family member 5 chr1 GO:0008284 Not Cancer Driver No 13 0.027 4 0 0.0 0
PRAMEF6 PRAMEF6 Q5VXH4 PRAME family member 6 chr1 GO:0008284 Not Cancer Driver No 47 0.099 4 2 0.5 0
PRAMEF7_ENST00000330881 PRAMEF7 Q5VXH5 PRAME family member 7 chr1 GO:0008284 Not Cancer Driver No 47 0.099 9 0 0.0 0
PRAME_ENST00000402697 PRAME P78395 Melanoma antigen preferentially expressed in tumors chr22 GO:0008284 Not Cancer Driver No 95 0.187 10 1 0.1 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 GO:0008284 Not Cancer Driver No 63 0.102 235 26 0.111 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0008284 Not Cancer Driver No 23 0.09 23 3 0.13 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0008284 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0008284 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0008284 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:0008284 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0008284 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0008284 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0008284 Compendium Yes 118 0.134 246 34 0.138 0
PRL PRL P01236 Prolactin chr6 GO:0008284 Not Cancer Driver No 49 0.216 22 1 0.045 0
PRLR PRLR P16471 Prolactin receptor chr5 GO:0008284 Not Cancer Driver No 154 0.248 282 70 0.248 2
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0008284 Not Cancer Driver No 50 0.135 18 1 0.056 0
PROK1 PROK1 P58294 Prokineticin-1 chr1 GO:0008284 Not Cancer Driver No 21 0.2 0 0 0.0 0
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0008284 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRRX1 PRRX1 P54821 Paired mesoderm homeobox protein 1 chr1 GO:0008284 Census, Compendium Yes 69 0.282 205 49 0.239 1
PRTN3 PRTN3 P24158 Myeloblastin chr19 GO:0008284 Not Cancer Driver No 20 0.078 46 1 0.022 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0008284 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0008284 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGFR PTGFR P43088 Prostaglandin F2-alpha receptor chr1 GO:0008284 Not Cancer Driver No 105 0.292 2 0 0.0 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0008284 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0008284 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTH1R_ENST00000449590 PTH1R Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor chr3 GO:0008284 Not Cancer Driver No 86 0.145 124 25 0.202 5
PTHLH_ENST00000539239 PTHLH P12272 Parathyroid hormone-related protein chr12 GO:0008284 Not Cancer Driver No 44 0.249 132 40 0.303 2
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0008284 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0008284 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTN PTN P21246 Pleiotrophin chr7 GO:0008284 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0008284 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0008284 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0008284 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRN PTPRN Q16849 Receptor-type tyrosine-protein phosphatase-like N chr2 GO:0008284 Not Cancer Driver No 142 0.145 498 73 0.147 0
PURA PURA Q00577 Transcriptional activator protein Pur-alpha chr5 GO:0008284 Not Cancer Driver No 22 0.068 188 10 0.053 6
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0008284 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAB25 RAB25 P57735 Ras-related protein Rab-25 chr1 GO:0008284 Not Cancer Driver No 26 0.122 32 5 0.156 0
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 GO:0008284 Not Cancer Driver No 31 0.161 0 0 0.0 2
RAD51B_ENST00000487270 RAD51B O15315 DNA repair protein RAD51 homolog 2 chr14 GO:0008284 Census Yes 45 0.117 13 0 0.0 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0008284 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARG RARG P13631 Retinoic acid receptor gamma chr12 GO:0008284 Not Cancer Driver No 82 0.181 164 24 0.146 0
RASAL3 RASAL3 Q86YV0 RAS protein activator like-3 chr19 GO:0008284 Not Cancer Driver No 114 0.113 536 68 0.127 0
RASSF10 RASSF10 A6NK89 Ras association domain-containing protein 10 chr11 GO:0008284 Not Cancer Driver No 11 0.022 372 8 0.022 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0008284 Not Cancer Driver No 49 0.098 151 19 0.126 2
RBPMS2 RBPMS2 Q6ZRY4 RNA-binding protein with multiple splicing 2 chr15 GO:0008284 Not Cancer Driver No 24 0.115 55 4 0.073 0
REG1A REG1A P05451 Lithostathine-1-alpha chr2 GO:0008284 Not Cancer Driver No 97 0.584 9 5 0.556 0
REG1B REG1B P48304 Lithostathine-1-beta chr2 GO:0008284 Not Cancer Driver No 91 0.548 14 8 0.571 0
REG3A_ENST00000305165 REG3A Q06141 Regenerating islet-derived protein 3-alpha chr2 GO:0008284 Not Cancer Driver No 93 0.531 19 10 0.526 0
REG3G REG3G Q6UW15 Regenerating islet-derived protein 3-gamma chr2 GO:0008284 Not Cancer Driver No 81 0.463 17 4 0.235 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0008284 Compendium Yes 75 0.136 400 48 0.12 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 GO:0008284 Not Cancer Driver No 26 0.136 22 5 0.227 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0008284 Not Cancer Driver No 63 0.117 143 20 0.14 0
RNASEH2B RNASEH2B Q5TBB1 Ribonuclease H2 subunit B chr13 GO:0008284 Not Cancer Driver No 34 0.109 84 9 0.107 14
RNF187_ENST00000639044 RNF187 Q5TA31 E3 ubiquitin-protein ligase RNF187 chr1 GO:0008284 Not Cancer Driver No 2 0.009 104 1 0.01 0
ROGDI ROGDI Q9GZN7 Protein rogdi homolog chr16 GO:0008284 Not Cancer Driver No 21 0.073 19 2 0.105 0
ROMO1_ENST00000397416 ROMO1 P60602 Reactive oxygen species modulator 1 chr20 GO:0008284 Not Cancer Driver No 9 0.114 0 0 0.0 0
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:0008284 Not Cancer Driver No 14 0.1 29 4 0.138 0
RPRD1B RPRD1B Q9NQG5 Regulation of nuclear pre-mRNA domain-containing protein 1B chr20 GO:0008284 Not Cancer Driver No 34 0.104 155 16 0.103 0
RPS15A_ENST00000565420 RPS15A P62244 40S ribosomal protein S15a chr16 GO:0008284 Not Cancer Driver No 6 0.046 4 0 0.0 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0008284 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS4X RPS4X P62701 40S ribosomal protein S4, X isoform chrX GO:0008284 Not Cancer Driver No 32 0.122 35 6 0.171 0
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 GO:0008284 Not Cancer Driver No 38 0.153 150 25 0.167 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0008284 Not Cancer Driver No 45 0.086 226 26 0.115 0
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 GO:0008284 Not Cancer Driver No 23 0.119 34 5 0.147 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0008284 Not Cancer Driver No 176 0.132 241 21 0.087 0
RREB1_ENST00000349384 RREB1 Q92766 Ras-responsive element-binding protein 1 chr6 GO:0008284 Not Cancer Driver No 213 0.126 1152 144 0.125 0
RTKN2 RTKN2 Q8IZC4 Rhotekin-2 chr10 GO:0008284 Not Cancer Driver No 71 0.117 158 21 0.133 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0008284 Not Cancer Driver No 121 0.102 866 82 0.095 0
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0008284 Not Cancer Driver No 83 0.159 447 73 0.163 47
S100A13_ENST00000392622 S100A13 Q99584 Protein S100-A13 chr1 GO:0008284 Not Cancer Driver No 12 0.122 6 0 0.0 0
S100A6_ENST00000496817 S100A6 P06703 Protein S100-A6 chr1 GO:0008284 Not Cancer Driver No 5 0.056 4 0 0.0 0
S100B S100B P04271 Protein S100-B chr21 GO:0008284 Not Cancer Driver No 17 0.185 13 1 0.077 0
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0008284 Not Cancer Driver No 86 0.225 29 6 0.207 0
S1PR2 S1PR2 O95136 Sphingosine 1-phosphate receptor 2 chr19 GO:0008284 Not Cancer Driver No 38 0.108 16 3 0.188 2
S1PR3 S1PR3 Q99500 Sphingosine 1-phosphate receptor 3 chr9 GO:0008284 Not Cancer Driver No 69 0.183 28 4 0.143 0
SAAL1 SAAL1 Q96ER3 Protein SAAL1 chr11 GO:0008284 Not Cancer Driver No 46 0.097 75 11 0.147 0
SAPCD2 SAPCD2 Q86UD0 Suppressor APC domain-containing protein 2 chr9 GO:0008284 Not Cancer Driver No 19 0.048 313 14 0.045 0
SASH3 SASH3 O75995 SAM and SH3 domain-containing protein 3 chrX GO:0008284 Not Cancer Driver No 59 0.155 327 49 0.15 0
SCG2 SCG2 P13521 Secretogranin-2 chr2 GO:0008284 Not Cancer Driver No 116 0.188 531 103 0.194 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0008284 Not Cancer Driver No 39 0.131 17 2 0.118 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0008284 Not Cancer Driver No 266 0.248 23 4 0.174 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:0008284 Not Cancer Driver No 142 0.364 47 28 0.596 0
SERPINB7 SERPINB7 O75635 Serpin B7 chr18 GO:0008284 Not Cancer Driver No 100 0.263 30 8 0.267 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0008284 Not Cancer Driver No 62 0.126 112 21 0.188 1
SERTAD1 SERTAD1 Q9UHV2 SERTA domain-containing protein 1 chr19 GO:0008284 Not Cancer Driver No 24 0.102 164 18 0.11 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0008284 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0008284 Not Cancer Driver No 47 0.159 1 0 0.0 0
SHANK2_ENST00000601538 SHANK2 Q9UPX8 SH3 and multiple ankyrin repeat domains protein 2 chr11 GO:0008284 Not Cancer Driver No 303 0.164 1379 262 0.19 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 GO:0008284 Not Cancer Driver No 84 0.144 397 58 0.146 0
SHC4 SHC4 Q6S5L8 SHC-transforming protein 4 chr15 GO:0008284 Not Cancer Driver No 74 0.117 325 44 0.135 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0008284 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHOX2_ENST00000441443 SHOX2 O60902 Short stature homeobox protein 2 chr3 GO:0008284 Not Cancer Driver No 67 0.202 200 40 0.2 0
SINHCAF_ENST00000454658 SINHCAF Q9NP50 SIN3-HDAC complex-associated factor chr12 GO:0008284 Not Cancer Driver No 24 0.109 108 10 0.093 0
SIRPG SIRPG Q9P1W8 Signal-regulatory protein gamma chr20 GO:0008284 Not Cancer Driver No 110 0.284 127 38 0.299 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0008284 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0008284 Not Cancer Driver No 33 0.093 164 12 0.073 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0008284 Census, Compendium Yes 49 0.173 144 25 0.174 8
SIX2 SIX2 Q9NPC8 Homeobox protein SIX2 chr2 GO:0008284 Census Yes 53 0.182 151 21 0.139 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0008284 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLC25A33 SLC25A33 Q9BSK2 Solute carrier family 25 member 33 chr1 GO:0008284 Not Cancer Driver No 23 0.072 4 0 0.0 0
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX GO:0008284 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC35F6 SLC35F6 Q8N357 Solute carrier family 35 member F6 chr2 GO:0008284 Not Cancer Driver No 33 0.089 13 0 0.0 0
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 GO:0008284 Not Cancer Driver No 111 0.134 417 63 0.151 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0008284 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMARCD3 SMARCD3 Q6STE5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 chr7 GO:0008284 Not Cancer Driver No 64 0.133 213 18 0.085 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0008284 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMPD3 SMPD3 Q9NY59 Sphingomyelin phosphodiesterase 3 chr16 GO:0008284 Not Cancer Driver No 92 0.14 224 29 0.129 0
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0008284 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0008284 Not Cancer Driver No 61 0.138 368 53 0.144 2
SOX15_ENST00000538513 SOX15 O60248 Protein SOX-15 chr17 GO:0008284 Not Cancer Driver No 18 0.077 227 18 0.079 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0008284 Not Cancer Driver No 28 0.059 400 24 0.06 4
SOX8 SOX8 P57073 Transcription factor SOX-8 chr16 GO:0008284 Not Cancer Driver No 43 0.096 403 39 0.097 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0008284 Compendium Yes 86 0.169 495 82 0.166 18
SP1 SP1 P08047 Transcription factor Sp1 chr12 GO:0008284 Not Cancer Driver No 96 0.122 599 71 0.119 0
SPDYA_ENST00000379579 SPDYA Q5MJ70 Speedy protein A chr2 GO:0008284 Not Cancer Driver No 39 0.125 119 11 0.092 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0008284 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0008284 Not Cancer Driver No 82 0.125 293 39 0.133 0
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 GO:0008284 Not Cancer Driver No 78 0.113 343 46 0.134 0
SRSF6 SRSF6 Q13247 Serine/arginine-rich splicing factor 6 chr20 GO:0008284 Not Cancer Driver No 69 0.201 259 49 0.189 0
SSR1 SSR1 P43307 Translocon-associated protein subunit alpha chr6 GO:0008284 Not Cancer Driver No 26 0.091 114 10 0.088 0
ST6GAL1 ST6GAL1 P15907 Beta-galactoside alpha-2,6-sialyltransferase 1 chr3 GO:0008284 Not Cancer Driver No 55 0.135 34 8 0.235 0
ST8SIA1 ST8SIA1 Q92185 Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase chr12 GO:0008284 Not Cancer Driver No 61 0.171 13 1 0.077 0
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 GO:0008284 Not Cancer Driver No 51 0.12 139 16 0.115 6
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0008284 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0008284 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT5A_ENST00000590949 STAT5A P42229 Signal transducer and activator of transcription 5A chr17 GO:0008284 Not Cancer Driver No 89 0.112 125 14 0.112 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0008284 Census, Compendium Yes 93 0.118 144 19 0.132 5
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:0008284 Not Cancer Driver No 121 0.122 659 83 0.126 2
STX3 STX3 Q13277 Syntaxin-3 chr11 GO:0008284 Not Cancer Driver No 51 0.176 129 30 0.233 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0008284 Not Cancer Driver No 50 0.168 152 20 0.132 0
STXBP4 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 GO:0008284 Not Cancer Driver No 78 0.141 211 24 0.114 0
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 GO:0008284 Census, Compendium Yes 83 0.112 483 46 0.095 3
SYF2 SYF2 O95926 Pre-mRNA-splicing factor SYF2 chr1 GO:0008284 Not Cancer Driver No 26 0.107 173 17 0.098 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0008284 Census Yes 96 0.151 131 27 0.206 5
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0008284 Not Cancer Driver No 69 0.17 28 2 0.071 0
TBC1D8_ENST00000376840 TBC1D8 O95759 TBC1 domain family member 8 chr2 GO:0008284 Not Cancer Driver No 164 0.144 224 28 0.125 0
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 GO:0008284 Not Cancer Driver No 74 0.117 60 2 0.033 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0008284 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0008284 Not Cancer Driver No 74 0.104 401 36 0.09 1
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0008284 Not Cancer Driver No 117 0.262 201 54 0.269 2
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0008284 Census, Compendium Yes 123 0.166 352 57 0.162 2
TBX5 TBX5 Q99593 T-box transcription factor TBX5 chr12 GO:0008284 Not Cancer Driver No 155 0.299 351 113 0.322 5
TBX6 TBX6 O95947 T-box transcription factor TBX6 chr16 GO:0008284 Not Cancer Driver No 44 0.101 253 25 0.099 0
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0008284 Compendium Yes 68 0.082 102 6 0.059 5
TCL1A TCL1A P56279 T-cell leukemia/lymphoma protein 1A chr14 GO:0008284 Census Yes 30 0.263 5 1 0.2 0
TDGF1 TDGF1 P13385 Teratocarcinoma-derived growth factor 1 chr3 GO:0008284 Not Cancer Driver No 39 0.207 25 2 0.08 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0008284 Not Cancer Driver No 219 0.195 126 22 0.175 10
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0008284 Census Yes 110 0.097 212 16 0.075 31
TET1 TET1 Q8NFU7 Methylcytosine dioxygenase TET1 chr10 GO:0008284 Census, Compendium Yes 316 0.148 1551 234 0.151 0
TFAP2B TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:0008284 Not Cancer Driver No 114 0.248 306 75 0.245 6
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0008284 Census Yes 89 0.117 80 6 0.075 1
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 GO:0008284 Not Cancer Driver No 20 0.125 0 0 0.0 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0008284 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0008284 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0008284 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0008284 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0008284 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0008284 Not Cancer Driver No 129 0.152 268 41 0.153 0
TGM1 TGM1 P22735 Protein-glutamine gamma-glutamyltransferase K chr14 GO:0008284 Not Cancer Driver No 118 0.144 230 37 0.161 65
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0008284 Not Cancer Driver No 188 0.161 320 58 0.181 0
THBS4 THBS4 P35443 Thrombospondin-4 chr5 GO:0008284 Not Cancer Driver No 137 0.143 281 40 0.142 0
THPO THPO P40225 Thrombopoietin chr3 GO:0008284 Not Cancer Driver No 63 0.178 163 25 0.153 0
TIAL1_ENST00000436547 TIAL1 Q01085 Nucleolysin TIAR chr10 GO:0008284 Not Cancer Driver No 45 0.12 122 12 0.098 0
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0008284 Not Cancer Driver No 370 0.233 810 194 0.24 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0008284 Not Cancer Driver No 92 0.129 443 66 0.149 1
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX GO:0008284 Not Cancer Driver No 25 0.121 0 0 0.0 0
TIPIN TIPIN Q9BVW5 TIMELESS-interacting protein chr15 GO:0008284 Not Cancer Driver No 26 0.086 242 19 0.079 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0008284 Not Cancer Driver No 28 0.127 80 6 0.075 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 GO:0008284 Not Cancer Driver No 198 0.113 1350 151 0.112 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0008284 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0008284 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMEM119 TMEM119 Q4V9L6 Transmembrane protein 119 chr12 GO:0008284 Not Cancer Driver No 59 0.208 195 47 0.241 0
TMEM250 TMEM250 H0YL14 Transmembrane protein 250 chr9 GO:0008284 Not Cancer Driver No 11 0.079 0 0 0.0 0
TMIGD2 TMIGD2 Q96BF3 Transmembrane and immunoglobulin domain-containing protein 2 chr19 GO:0008284 Not Cancer Driver No 57 0.202 120 32 0.267 0
TNC TNC P24821 Tenascin chr9 GO:0008284 Census, Compendium Yes 354 0.161 568 123 0.217 2
TNF TNF P01375 Tumor necrosis factor chr6 GO:0008284 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0008284 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0008284 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFRSF13C TNFRSF13C Q96RJ3 Tumor necrosis factor receptor superfamily member 13C chr22 GO:0008284 Not Cancer Driver No 17 0.092 128 15 0.117 0
TNFRSF4 TNFRSF4 P43489 Tumor necrosis factor receptor superfamily member 4 chr1 GO:0008284 Not Cancer Driver No 30 0.108 94 14 0.149 1
TNFSF12 TNFSF12 O43508 Tumor necrosis factor ligand superfamily member 12 chr17 GO:0008284 Not Cancer Driver No 28 0.112 109 8 0.073 0
TNFSF13 TNFSF13 O75888 Tumor necrosis factor ligand superfamily member 13 chr17 GO:0008284 Not Cancer Driver No 14 0.056 109 6 0.055 0
TNFSF13B TNFSF13B Q9Y275 Tumor necrosis factor ligand superfamily member 13B chr13 GO:0008284 Not Cancer Driver No 41 0.144 91 15 0.165 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0008284 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNFSF9 TNFSF9 P41273 Tumor necrosis factor ligand superfamily member 9 chr19 GO:0008284 Not Cancer Driver No 32 0.126 39 4 0.103 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0008284 Not Cancer Driver No 112 0.213 494 108 0.219 0
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0008284 Census, Compendium Yes 229 0.337 398 143 0.359 28
TRAF5_ENST00000336184 TRAF5 O00463 TNF receptor-associated factor 5 chr1 GO:0008284 Not Cancer Driver No 61 0.11 59 5 0.085 0
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0008284 Not Cancer Driver No 255 0.262 148 32 0.216 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0008284 Not Cancer Driver No 152 0.125 149 18 0.121 12
TSHR TSHR P16473 Thyrotropin receptor chr14 GO:0008284 Census Yes 128 0.168 38 9 0.237 39
TSLP TSLP Q969D9 Thymic stromal lymphopoietin chr5 GO:0008284 Not Cancer Driver No 27 0.17 16 0 0.0 0
TSPAN31 TSPAN31 Q12999 Tetraspanin-31 chr12 GO:0008284 Not Cancer Driver No 22 0.105 0 0 0.0 0
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0008284 Not Cancer Driver No 5 0.03 1 0 0.0 0
TSPYL5 TSPYL5 Q86VY4 Testis-specific Y-encoded-like protein 5 chr8 GO:0008284 Not Cancer Driver No 92 0.221 257 61 0.237 0
TTK TTK P33981 Dual specificity protein kinase TTK chr6 GO:0008284 Not Cancer Driver No 136 0.159 352 46 0.131 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 GO:0008284 Not Cancer Driver No 148 0.125 213 29 0.136 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX GO:0008284 Compendium Yes 35 0.23 67 13 0.194 2
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 GO:0008284 Not Cancer Driver No 109 0.137 141 24 0.17 0
VASH2 VASH2 Q86V25 Tubulinyl-Tyr carboxypeptidase 2 chr1 GO:0008284 Not Cancer Driver No 32 0.09 106 9 0.085 0
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0008284 Not Cancer Driver No 153 0.181 102 18 0.176 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0008284 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFB VEGFB P49765 Vascular endothelial growth factor B chr11 GO:0008284 Not Cancer Driver No 25 0.121 125 22 0.176 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0008284 Not Cancer Driver No 128 0.305 37 12 0.324 0
VEGFD VEGFD O43915 Vascular endothelial growth factor D chrX GO:0008284 Not Cancer Driver No 59 0.167 33 6 0.182 0
VIP VIP P01282 VIP peptides chr6 GO:0008284 Not Cancer Driver No 58 0.341 77 25 0.325 0
VIPR1 VIPR1 P32241 Vasoactive intestinal polypeptide receptor 1 chr3 GO:0008284 Not Cancer Driver No 41 0.09 10 2 0.2 0
VSTM2A_ENST00000407838 VSTM2A Q8TAG5 V-set and transmembrane domain-containing protein 2A chr7 GO:0008284 Not Cancer Driver No 87 0.369 121 42 0.347 0
WAPL_ENST00000618527 WAPL Q7Z5K2 Wings apart-like protein homolog chr10 GO:0008284 Not Cancer Driver No 140 0.118 621 68 0.11 0
WDR62_ENST00000270301 WDR62 O43379 WD repeat-containing protein 62 chr19 GO:0008284 Not Cancer Driver No 181 0.119 792 100 0.126 5
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0008284 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0008284 Not Cancer Driver No 56 0.144 84 16 0.19 2
WNT2 WNT2 P09544 Protein Wnt-2 chr7 GO:0008284 Not Cancer Driver No 85 0.236 11 3 0.273 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0008284 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0008284 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0008284 Not Cancer Driver No 93 0.266 18 9 0.5 4
WWTR1_ENST00000360632 WWTR1 Q9GZV5 WW domain-containing transcription regulator protein 1 chr3 GO:0008284 Census Yes 41 0.102 387 41 0.106 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0008284 Not Cancer Driver No 19 0.073 169 9 0.053 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0008284 Not Cancer Driver No 28 0.246 35 11 0.314 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0008284 Not Cancer Driver No 51 0.101 489 49 0.1 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0008284 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZFPM2 ZFPM2 Q8WW38 Zinc finger protein ZFPM2 chr8 GO:0008284 Not Cancer Driver No 374 0.325 659 233 0.354 8
ZMIZ1 ZMIZ1 Q9ULJ6 Zinc finger MIZ domain-containing protein 1 chr10 GO:0008284 Not Cancer Driver No 148 0.139 762 111 0.146 5
ZNF143 ZNF143 P52747 Zinc finger protein 143 chr11 GO:0008284 Not Cancer Driver No 67 0.105 425 49 0.115 0
ZNF16 ZNF16 P17020 Zinc finger protein 16 chr8 GO:0008284 Not Cancer Driver No 99 0.145 293 40 0.137 0
ZNF268_ENST00000228289 ZNF268 Q14587 Zinc finger protein 268 chr12 GO:0008284 Not Cancer Driver No 96 0.101 63 9 0.143 0
ZNF335 ZNF335 Q9H4Z2 Zinc finger protein 335 chr20 GO:0008284 Not Cancer Driver No 185 0.138 942 133 0.141 1
ZNF580_ENST00000545125 ZNF580 Q9UK33 Zinc finger protein 580 chr19 GO:0008284 Not Cancer Driver No 8 0.047 153 8 0.052 0
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0008284 Not Cancer Driver No 26 0.044 415 14 0.034 0