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Total number of protein in "GO:0008283" GO term:  392

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCB1_ENST00000265724 ABCB1 P08183 ATP-dependent translocase ABCB1 chr7 GO:0008283 Compendium Yes 367 0.287 103 31 0.301 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0008283 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0008283 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACVR1C ACVR1C Q8NER5 Activin receptor type-1C chr2 GO:0008283 Not Cancer Driver No 90 0.183 3 1 0.333 0
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0008283 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0008283 Not Cancer Driver No 93 0.185 60 11 0.183 82
AGT AGT P01019 Angiotensinogen chr1 GO:0008283 Not Cancer Driver No 85 0.179 33 10 0.303 1
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0008283 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALKBH3 ALKBH3 Q96Q83 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 chr11 GO:0008283 Not Cancer Driver No 42 0.147 157 25 0.159 0
ANGPTL8_ENST00000252453 ANGPTL8 Q6UXH0 Angiopoietin-like protein 8 chr19 GO:0008283 Not Cancer Driver No 17 0.086 26 6 0.231 0
ANKRD45 ANKRD45 Q5TZF3 Ankyrin repeat domain-containing protein 45 chr1 GO:0008283 Not Cancer Driver No 60 0.226 101 22 0.218 0
AREG AREG P15514 Amphiregulin chr4 GO:0008283 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARID2 ARID2 Q68CP9 AT-rich interactive domain-containing protein 2 chr12 GO:0008283 Census, Compendium Yes 272 0.148 1143 141 0.123 0
ARIH2 ARIH2 O95376 E3 ubiquitin-protein ligase ARIH2 chr3 GO:0008283 Not Cancer Driver No 64 0.13 85 11 0.129 0
ARTN_ENST00000372354 ARTN Q5T4W7 Artemin chr1 GO:0008283 Not Cancer Driver No 11 0.05 154 6 0.039 0
ARX ARX Q96QS3 Homeobox protein ARX chrX GO:0008283 Not Cancer Driver No 33 0.059 423 18 0.043 9
ASCC3 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 GO:0008283 Not Cancer Driver No 279 0.127 87 8 0.092 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0008283 Not Cancer Driver No 33 0.14 182 24 0.132 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0008283 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0008283 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF5_ENST00000595125 ATF5 Q9Y2D1 Cyclic AMP-dependent transcription factor ATF-5 chr19 GO:0008283 Not Cancer Driver No 47 0.167 239 40 0.167 0
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0008283 Not Cancer Driver No 31 0.097 254 23 0.091 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0008283 Not Cancer Driver No 51 0.148 63 8 0.127 0
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0008283 Census, Compendium Yes 114 0.135 547 77 0.141 0
AZI2 AZI2 Q9H6S1 5-azacytidine-induced protein 2 chr3 GO:0008283 Not Cancer Driver No 31 0.079 192 13 0.068 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0008283 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0008283 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0008283 Census Yes 30 0.156 39 2 0.051 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0008283 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0008283 Not Cancer Driver No 22 0.114 34 6 0.176 0
BLOC1S2 BLOC1S2 Q6QNY1 Biogenesis of lysosome-related organelles complex 1 subunit 2 chr10 GO:0008283 Not Cancer Driver No 17 0.12 34 6 0.176 0
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0008283 Not Cancer Driver No 88 0.208 87 13 0.149 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0008283 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0008283 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0008283 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMPER BMPER Q8N8U9 BMP-binding endothelial regulator protein chr7 GO:0008283 Not Cancer Driver No 196 0.286 0 0 0.0 1
BOP1 BOP1 Q14137 Ribosome biogenesis protein BOP1 chr8 GO:0008283 Not Cancer Driver No 20 0.027 304 19 0.062 0
BRAT1 BRAT1 Q6PJG6 BRCA1-associated ATM activator 1 chr7 GO:0008283 Not Cancer Driver No 112 0.136 101 13 0.129 0
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:0008283 Census, Compendium Yes 457 0.134 1542 225 0.146 46
BTBD10_ENST00000278174 BTBD10 Q9BSF8 BTB/POZ domain-containing protein 10 chr11 GO:0008283 Not Cancer Driver No 59 0.124 252 31 0.123 0
BTN3A1 BTN3A1 O00481 Butyrophilin subfamily 3 member A1 chr6 GO:0008283 Not Cancer Driver No 77 0.15 72 18 0.25 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0008283 Not Cancer Driver No 80 0.132 45 4 0.089 0
BUB1 BUB1 O43683 Mitotic checkpoint serine/threonine-protein kinase BUB1 chr2 GO:0008283 Not Cancer Driver No 139 0.128 466 64 0.137 0
BYSL BYSL Q13895 Bystin chr6 GO:0008283 Not Cancer Driver No 38 0.087 176 14 0.08 0
CADM1_ENST00000452722 CADM1 Q9BY67 Cell adhesion molecule 1 chr11 GO:0008283 Not Cancer Driver No 106 0.24 103 28 0.272 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0008283 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0008283 Not Cancer Driver No 66 0.185 19 1 0.053 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0008283 Census, Compendium Yes 55 0.186 31 25 0.806 0
CD180 CD180 Q99467 CD180 antigen chr5 GO:0008283 Not Cancer Driver No 105 0.159 0 0 0.0 0
CD19_ENST00000324662 CD19 P15391 B-lymphocyte antigen CD19 chr16 GO:0008283 Not Cancer Driver No 80 0.144 312 46 0.147 0
CD34 CD34 P28906 Hematopoietic progenitor cell antigen CD34 chr1 GO:0008283 Not Cancer Driver No 65 0.169 221 34 0.154 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0008283 Census Yes 31 0.105 185 20 0.108 0
CDC25A CDC25A P30304 M-phase inducer phosphatase 1 chr3 GO:0008283 Not Cancer Driver No 63 0.12 313 35 0.112 0
CDC25C CDC25C P30307 M-phase inducer phosphatase 3 chr5 GO:0008283 Not Cancer Driver No 61 0.129 224 26 0.116 0
CDH13_ENST00000567109 CDH13 P55290 Cadherin-13 chr16 GO:0008283 Not Cancer Driver No 168 0.236 235 59 0.251 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0008283 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK3_ENST00000448471 CDK3 Q00526 Cyclin-dependent kinase 3 chr17 GO:0008283 Not Cancer Driver No 40 0.131 17 2 0.118 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0008283 Not Cancer Driver No 50 0.099 99 20 0.202 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:0008283 Not Cancer Driver No 50 0.134 34 2 0.059 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0008283 Not Cancer Driver No 64 0.122 241 25 0.104 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0008283 Not Cancer Driver No 3 0.009 276 2 0.007 0
CEMP1 CEMP1 Q6PRD7 Cementoblastoma-derived protein 1 chr16 GO:0008283 Not Cancer Driver No 44 0.178 192 35 0.182 0
CER1 CER1 O95813 Cerberus chr9 GO:0008283 Not Cancer Driver No 70 0.262 119 27 0.227 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0008283 Not Cancer Driver No 58 0.122 86 16 0.186 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0008283 Not Cancer Driver No 23 0.085 230 18 0.078 0
CKS1B CKS1B P61024 Cyclin-dependent kinases regulatory subunit 1 chr1 GO:0008283 Not Cancer Driver No 10 0.127 10 0 0.0 0
CKS2 CKS2 P33552 Cyclin-dependent kinases regulatory subunit 2 chr9 GO:0008283 Not Cancer Driver No 9 0.114 10 2 0.2 0
CLEC12B CLEC12B Q2HXU8 C-type lectin domain family 12 member B chr12 GO:0008283 Not Cancer Driver No 34 0.123 57 8 0.14 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0008283 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNTNAP2 CNTNAP2 Q9UHC6 Contactin-associated protein-like 2 chr7 GO:0008283 Census Yes 570 0.428 161 82 0.509 0
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0008283 Census Yes 402 0.274 1182 337 0.285 103
COL4A3BP_ENST00000261415 CERT1 Q9Y5P4 Ceramide transfer protein chr5 GO:0008283 Not Cancer Driver No 73 0.117 215 23 0.107 2
COMP COMP P49747 Cartilage oligomeric matrix protein chr19 GO:0008283 Not Cancer Driver No 97 0.128 306 52 0.17 61
COPS2_ENST00000388901 COPS2 P61201 COP9 signalosome complex subunit 2 chr15 GO:0008283 Not Cancer Driver No 59 0.133 59 9 0.153 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0008283 Not Cancer Driver No 64 0.163 135 14 0.104 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0008283 Census Yes 133 0.137 124 17 0.137 20
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0008283 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSPG4 CSPG4 Q6UVK1 Chondroitin sulfate proteoglycan 4 chr15 GO:0008283 Not Cancer Driver No 259 0.112 838 85 0.101 0
CTC1 CTC1 Q2NKJ3 CST complex subunit CTC1 chr17 GO:0008283 Not Cancer Driver No 142 0.117 103 8 0.078 9
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0008283 Census, Compendium Yes 415 0.531 288 301 1.045 14
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 GO:0008283 Not Cancer Driver No 151 0.195 65 9 0.138 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0008283 Not Cancer Driver No 66 0.166 259 44 0.17 0
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0008283 Not Cancer Driver No 81 0.158 17 2 0.118 0
DACH1_ENST00000619232 DACH1 Q9UI36 Dachshund homolog 1 chr13 GO:0008283 Not Cancer Driver No 157 0.207 641 134 0.209 0
DAGLA DAGLA Q9Y4D2 Diacylglycerol lipase-alpha chr11 GO:0008283 Not Cancer Driver No 165 0.158 315 43 0.137 0
DAGLB DAGLB Q8NCG7 Diacylglycerol lipase-beta chr7 GO:0008283 Not Cancer Driver No 69 0.103 37 3 0.081 0
DAZAP1 DAZAP1 Q96EP5 DAZ-associated protein 1 chr19 GO:0008283 Compendium Yes 53 0.13 327 45 0.138 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 GO:0008283 Not Cancer Driver No 84 0.129 510 73 0.143 0
DCHS1 DCHS1 Q96JQ0 Protocadherin-16 chr11 GO:0008283 Not Cancer Driver No 444 0.135 2197 317 0.144 3
DCHS2_ENST00000357232 DCHS2 Q6V1P9 Protocadherin-23 chr4 GO:0008283 Not Cancer Driver No 645 0.191 897 152 0.169 0
DDR2 DDR2 Q16832 Discoidin domain-containing receptor 2 chr1 GO:0008283 Census Yes 192 0.225 118 34 0.288 7
DDX41 DDX41 Q9UJV9 Probable ATP-dependent RNA helicase DDX41 chr5 GO:0008283 Not Cancer Driver No 82 0.132 180 26 0.144 1
DIO3 DIO3 P55073 Thyroxine 5-deiodinase chr14 GO:0008283 Not Cancer Driver No 88 0.289 71 18 0.254 0
DIPK2A DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 GO:0008283 Not Cancer Driver No 56 0.13 9 0 0.0 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 GO:0008283 Not Cancer Driver No 132 0.155 514 82 0.16 0
DLX5 DLX5 P56178 Homeobox protein DLX-5 chr7 GO:0008283 Not Cancer Driver No 71 0.246 223 57 0.256 1
DMRT1 DMRT1 Q9Y5R6 Doublesex- and mab-3-related transcription factor 1 chr9 GO:0008283 Not Cancer Driver No 60 0.161 282 47 0.167 0
DOCK2 DOCK2 Q92608 Dedicator of cytokinesis protein 2 chr5 GO:0008283 Not Cancer Driver No 480 0.262 266 79 0.297 2
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0008283 Not Cancer Driver No 321 0.153 312 60 0.192 1
E2F8_ENST00000250024 E2F8 A0AVK6 Transcription factor E2F8 chr11 GO:0008283 Not Cancer Driver No 132 0.152 582 85 0.146 0
ECD_ENST00000372979 ECD O95905 Protein ecdysoneless homolog chr10 GO:0008283 Not Cancer Driver No 68 0.106 254 26 0.102 0
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0008283 Not Cancer Driver No 62 0.145 21 6 0.286 2
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0008283 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2S2 EIF2S2 P20042 Eukaryotic translation initiation factor 2 subunit 2 chr20 GO:0008283 Not Cancer Driver No 37 0.111 185 12 0.065 0
ELF4 ELF4 Q99607 ETS-related transcription factor Elf-4 chrX GO:0008283 Census, Compendium Yes 88 0.133 486 60 0.123 0
EML1_ENST00000262233 EML1 O00423 Echinoderm microtubule-associated protein-like 1 chr14 GO:0008283 Not Cancer Driver No 146 0.179 205 31 0.151 2
EMP2_ENST00000536829 EMP2 P54851 Epithelial membrane protein 2 chr16 GO:0008283 Not Cancer Driver No 24 0.144 0 0 0.0 2
EMX2 EMX2 Q04743 Homeobox protein EMX2 chr10 GO:0008283 Not Cancer Driver No 34 0.135 147 21 0.143 0
ENPEP ENPEP Q07075 Glutamyl aminopeptidase chr4 GO:0008283 Compendium Yes 235 0.246 130 44 0.338 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0008283 Compendium Yes 171 0.175 187 39 0.209 3
EPHB1 EPHB1 P54762 Ephrin type-B receptor 1 chr3 GO:0008283 Not Cancer Driver No 316 0.321 67 17 0.254 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0008283 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0008283 Census, Compendium Yes 150 0.197 5 0 0.0 35
EREG EREG O14944 Proepiregulin chr4 GO:0008283 Not Cancer Driver No 26 0.154 10 3 0.3 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0008283 Census, Compendium Yes 121 0.203 195 27 0.138 2
ETV6 ETV6 P41212 Transcription factor ETV6 chr12 GO:0008283 Census, Compendium Yes 98 0.217 251 46 0.183 3
EXT1 EXT1 Q16394 Exostosin-1 chr8 GO:0008283 Census Yes 107 0.143 58 7 0.121 12
FAM83A FAM83A Q86UY5 Protein FAM83A chr8 GO:0008283 Not Cancer Driver No 69 0.159 198 24 0.121 0
FAM83B FAM83B Q5T0W9 Protein FAM83B chr6 GO:0008283 Not Cancer Driver No 314 0.311 684 219 0.32 0
FAM83D FAM83D Q9H4H8 Protein FAM83D chr20 GO:0008283 Not Cancer Driver No 70 0.12 273 29 0.106 0
FAP FAP Q12884 Prolyl endopeptidase FAP chr2 GO:0008283 Not Cancer Driver No 158 0.208 6 2 0.333 0
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0008283 Not Cancer Driver No 55 0.142 68 7 0.103 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0008283 Not Cancer Driver No 68 0.114 120 4 0.033 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0008283 Not Cancer Driver No 114 0.139 145 21 0.145 0
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0008283 Not Cancer Driver No 100 0.148 65 8 0.123 2
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0008283 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0008283 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGF4 FGF4 P08620 Fibroblast growth factor 4 chr11 GO:0008283 Not Cancer Driver No 16 0.078 21 3 0.143 0
FGF7 FGF7 P21781 Fibroblast growth factor 7 chr15 GO:0008283 Not Cancer Driver No 38 0.196 22 4 0.182 0
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0008283 Not Cancer Driver No 30 0.129 79 9 0.114 6
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0008283 Census, Compendium Yes 238 0.29 228 44 0.193 72
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 GO:0008283 Census, Compendium Yes 173 0.215 241 26 0.108 37
FGL1_ENST00000381840 FGL1 Q08830 Fibrinogen-like protein 1 chr8 GO:0008283 Not Cancer Driver No 42 0.135 10 2 0.2 0
FIGNL1 FIGNL1 Q6PIW4 Fidgetin-like protein 1 chr7 GO:0008283 Not Cancer Driver No 75 0.111 224 23 0.103 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0008283 Census, Compendium Yes 200 0.201 64 27 0.422 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0008283 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0008283 Not Cancer Driver No 63 0.126 369 33 0.089 1
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0008283 Not Cancer Driver No 69 0.136 415 58 0.14 0
FSHB_ENST00000254122 FSHB P01225 Follitropin subunit beta chr11 GO:0008283 Not Cancer Driver No 31 0.24 0 0 0.0 1
FST FST P19883 Follistatin chr5 GO:0008283 Not Cancer Driver No 50 0.145 20 7 0.35 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0008283 Not Cancer Driver No 92 0.171 70 13 0.186 0
FZD3_ENST00000240093 FZD3 Q9NPG1 Frizzled-3 chr8 GO:0008283 Not Cancer Driver No 64 0.096 141 13 0.092 0
FZD6 FZD6 O60353 Frizzled-6 chr8 GO:0008283 Not Cancer Driver No 95 0.135 172 15 0.087 1
FZD9 FZD9 O00144 Frizzled-9 chr7 GO:0008283 Not Cancer Driver No 55 0.093 61 0 0.0 0
GAPT GAPT Q8N292 Protein GAPT chr5 GO:0008283 Not Cancer Driver No 41 0.261 83 27 0.325 0
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0008283 Not Cancer Driver No 74 0.138 38 5 0.132 171
GBX2 GBX2 P52951 Homeobox protein GBX-2 chr2 GO:0008283 Not Cancer Driver No 43 0.124 243 31 0.128 0
GINS1 GINS1 Q14691 DNA replication complex GINS protein PSF1 chr20 GO:0008283 Not Cancer Driver No 21 0.107 18 3 0.167 2
GINS4 GINS4 Q9BRT9 DNA replication complex GINS protein SLD5 chr8 GO:0008283 Not Cancer Driver No 32 0.143 77 14 0.182 0
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0008283 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 GO:0008283 Not Cancer Driver No 66 0.177 104 21 0.202 2
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0008283 Compendium Yes 50 0.141 24 0 0.0 0
GNAT1 GNAT1 P11488 Guanine nucleotide-binding protein G(t) subunit alpha-1 chr3 GO:0008283 Not Cancer Driver No 43 0.123 39 6 0.154 3
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 GO:0008283 Not Cancer Driver No 45 0.132 24 2 0.083 16
GNG2_ENST00000615906 GNG2 P59768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 chr14 GO:0008283 Not Cancer Driver No 17 0.239 12 3 0.25 0
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 GO:0008283 Not Cancer Driver No 56 0.102 257 21 0.082 0
GOLGB1_ENST00000340645 GOLGB1 Q14789 Golgin subfamily B member 1 chr3 GO:0008283 Not Cancer Driver No 403 0.124 2416 300 0.124 0
GPC3_ENST00000370818 GPC3 P51654 Glypican-3 chrX GO:0008283 Census Yes 89 0.153 86 11 0.128 1
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0008283 Not Cancer Driver No 38 0.187 12 1 0.083 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0008283 Not Cancer Driver No 95 0.152 258 43 0.167 2
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0008283 Not Cancer Driver No 32 0.152 0 0 0.0 0
H3F3A_ENST00000366816 H3-3B P84243 Histone H3.3 chr1 GO:0008283 Not Cancer Driver No 32 0.235 51 22 0.431 3
H3F3B_ENST00000589599 H3-3B P84243 Histone H3.3 chr17 GO:0008283 Not Cancer Driver No 28 0.206 51 14 0.275 3
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0008283 Not Cancer Driver No 47 0.217 124 29 0.234 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0008283 Compendium Yes 233 0.32 43 16 0.372 0
HHIP HHIP Q96QV1 Hedgehog-interacting protein chr4 GO:0008283 Not Cancer Driver No 150 0.214 73 34 0.466 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0008283 Census Yes 12 0.11 109 12 0.11 0
HOXB4 HOXB4 P17483 Homeobox protein Hox-B4 chr17 GO:0008283 Not Cancer Driver No 41 0.163 210 33 0.157 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0008283 Not Cancer Driver No 14 0.104 52 7 0.135 0
ID4 ID4 P47928 DNA-binding protein inhibitor ID-4 chr6 GO:0008283 Not Cancer Driver No 4 0.025 71 1 0.014 0
IFT20_ENST00000395418 IFT20 Q8IY31 Intraflagellar transport protein 20 homolog chr17 GO:0008283 Not Cancer Driver No 11 0.083 0 0 0.0 0
IFT80 IFT80 Q9P2H3 Intraflagellar transport protein 80 homolog chr3 GO:0008283 Not Cancer Driver No 117 0.151 21 2 0.095 2
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0008283 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 GO:0008283 Not Cancer Driver No 141 0.244 298 80 0.268 0
IGFBP4 IGFBP4 P22692 Insulin-like growth factor-binding protein 4 chr17 GO:0008283 Not Cancer Driver No 24 0.093 106 17 0.16 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0008283 Not Cancer Driver No 27 0.099 112 17 0.152 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0008283 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0008283 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0008283 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0008283 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0008283 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0008283 Not Cancer Driver No 35 0.165 58 7 0.121 0
IRF2 IRF2 P14316 Interferon regulatory factor 2 chr4 GO:0008283 Not Cancer Driver No 85 0.244 288 73 0.253 0
IRF6 IRF6 O14896 Interferon regulatory factor 6 chr1 GO:0008283 Not Cancer Driver No 97 0.208 173 36 0.208 45
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0008283 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0008283 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0008283 Not Cancer Driver No 148 0.156 719 119 0.166 0
JUNB JUNB P17275 Transcription factor JunB chr19 GO:0008283 Not Cancer Driver No 20 0.058 305 16 0.052 0
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 GO:0008283 Not Cancer Driver No 183 0.135 804 100 0.124 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0008283 Not Cancer Driver No 88 0.105 251 17 0.068 0
KCNA1 KCNA1 Q09470 Potassium voltage-gated channel subfamily A member 1 chr12 GO:0008283 Not Cancer Driver No 176 0.356 69 34 0.493 17
KCTD13 KCTD13 Q8WZ19 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 chr16 GO:0008283 Not Cancer Driver No 33 0.1 95 10 0.105 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 GO:0008283 Not Cancer Driver No 222 0.135 774 102 0.132 2
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0008283 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLK8_ENST00000600767 KLK8 O60259 Kallikrein-8 chr19 GO:0008283 Not Cancer Driver No 65 0.25 76 15 0.197 0
KPNA1 KPNA1 P52294 Importin subunit alpha-5 chr3 GO:0008283 Not Cancer Driver No 65 0.121 121 18 0.149 0
KRT2 KRT2 P35908 Keratin, type II cytoskeletal 2 epidermal chr12 GO:0008283 Not Cancer Driver No 122 0.191 335 59 0.176 15
LEPR LEPR P48357 Leptin receptor chr1 GO:0008283 Not Cancer Driver No 243 0.209 57 11 0.193 0
LGI4 LGI4 Q8N135 Leucine-rich repeat LGI family member 4 chr19 GO:0008283 Not Cancer Driver No 54 0.101 4 1 0.25 2
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 GO:0008283 Not Cancer Driver No 108 0.114 16 3 0.188 0
LGR5 LGR5 O75473 Leucine-rich repeat-containing G-protein coupled receptor 5 chr12 GO:0008283 Not Cancer Driver No 124 0.137 13 2 0.154 0
LHX5 LHX5 Q9H2C1 LIM/homeobox protein Lhx5 chr12 GO:0008283 Not Cancer Driver No 45 0.112 253 22 0.087 0
LHX9 LHX9 Q9NQ69 LIM/homeobox protein Lhx9 chr1 GO:0008283 Not Cancer Driver No 97 0.244 191 46 0.241 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0008283 Not Cancer Driver No 134 0.147 63 10 0.159 2
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0008283 Not Cancer Driver No 203 0.312 291 97 0.333 0
LIPA LIPA P38571 Lysosomal acid lipase/cholesteryl ester hydrolase chr10 GO:0008283 Not Cancer Driver No 44 0.11 12 1 0.083 4
LIPG LIPG Q9Y5X9 Endothelial lipase chr18 GO:0008283 Not Cancer Driver No 90 0.18 59 7 0.119 0
LMNTD1_ENST00000282881 LMNTD1 Q8N9Z9 Lamin tail domain-containing protein 1 chr12 GO:0008283 Not Cancer Driver No 71 0.183 129 24 0.186 0
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0008283 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRRC17 LRRC17 Q8N6Y2 Leucine-rich repeat-containing protein 17 chr7 GO:0008283 Not Cancer Driver No 58 0.132 88 11 0.125 0
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 GO:0008283 Not Cancer Driver No 103 0.119 301 30 0.1 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0008283 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAP4K1 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 GO:0008283 Not Cancer Driver No 116 0.139 276 41 0.149 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0008283 Census, Compendium Yes 62 0.172 2 0 0.0 7
MCM10 MCM10 Q7L590 Protein MCM10 homolog chr10 GO:0008283 Not Cancer Driver No 152 0.174 535 102 0.191 1
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 GO:0008283 Not Cancer Driver No 101 0.14 128 22 0.172 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 GO:0008283 Census, Compendium Yes 287 0.233 749 159 0.212 3
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0008283 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0008283 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEGF10_ENST00000503335 MEGF10 Q96KG7 Multiple epidermal growth factor-like domains protein 10 chr5 GO:0008283 Not Cancer Driver No 216 0.189 204 42 0.206 2
MELK MELK Q14680 Maternal embryonic leucine zipper kinase chr9 GO:0008283 Not Cancer Driver No 76 0.117 162 24 0.148 0
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 GO:0008283 Not Cancer Driver No 540 0.166 3169 529 0.167 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0008283 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP16 MMP16 P51512 Matrix metalloproteinase-16 chr8 GO:0008283 Not Cancer Driver No 235 0.387 168 61 0.363 0
MORF4L1 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 GO:0008283 Not Cancer Driver No 43 0.119 163 17 0.104 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0008283 Not Cancer Driver No 84 0.119 292 35 0.12 1
MRPS27_ENST00000261413 MRPS27 Q92552 28S ribosomal protein S27, mitochondrial chr5 GO:0008283 Not Cancer Driver No 46 0.111 51 7 0.137 0
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:0008283 Not Cancer Driver No 39 0.129 197 16 0.081 7
MTSS1_ENST00000518547 MTSS1 O43312 Protein MTSS 1 chr8 GO:0008283 Not Cancer Driver No 107 0.142 584 86 0.147 0
MUS81 MUS81 Q96NY9 Crossover junction endonuclease MUS81 chr11 GO:0008283 Not Cancer Driver No 67 0.122 232 38 0.164 0
MUSTN1 MUSTN1 Q8IVN3 Musculoskeletal embryonic nuclear protein 1 chr3 GO:0008283 Not Cancer Driver No 11 0.134 82 11 0.134 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0008283 Census, Compendium Yes 80 0.182 299 46 0.154 0
NAA35 NAA35 Q5VZE5 N-alpha-acetyltransferase 35, NatC auxiliary subunit chr9 GO:0008283 Not Cancer Driver No 87 0.12 120 22 0.183 0
NAA60_ENST00000572584 NAA60 Q9H7X0 N-alpha-acetyltransferase 60 chr16 GO:0008283 Not Cancer Driver No 33 0.136 0 0 0.0 0
NBN NBN O60934 Nibrin chr8 GO:0008283 Census Yes 90 0.119 417 54 0.129 1
NCAPG2_ENST00000356309 NCAPG2 Q86XI2 Condensin-2 complex subunit G2 chr7 GO:0008283 Not Cancer Driver No 113 0.099 72 8 0.111 3
NDE1_ENST00000396354 NDE1 Q9NXR1 Nuclear distribution protein nudE homolog 1 chr16 GO:0008283 Not Cancer Driver No 45 0.134 316 42 0.133 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0008283 Not Cancer Driver No 32 0.093 202 16 0.079 0
NDRG4_ENST00000570248 NDRG4 Q9ULP0 Protein NDRG4 chr16 GO:0008283 Not Cancer Driver No 44 0.125 90 11 0.122 0
NDST1 NDST1 P52848 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 chr5 GO:0008283 Not Cancer Driver No 117 0.133 22 1 0.045 4
NDUFS2 NDUFS2 O75306 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial chr1 GO:0008283 Not Cancer Driver No 58 0.125 49 5 0.102 4
NES NES P48681 Nestin chr1 GO:0008283 Not Cancer Driver No 271 0.167 1474 253 0.172 0
NEUROD4 NEUROD4 Q9HD90 Neurogenic differentiation factor 4 chr12 GO:0008283 Not Cancer Driver No 123 0.372 236 83 0.352 0
NF2 NF2 P35240 Merlin chr22 GO:0008283 Census, Compendium Yes 69 0.116 252 26 0.103 16
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0008283 Not Cancer Driver No 80 0.193 409 77 0.188 3
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0008283 Not Cancer Driver No 48 0.148 181 22 0.122 55
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0008283 Not Cancer Driver No 35 0.15 171 16 0.094 0
NKX6-1 NKX6-1 P78426 Homeobox protein Nkx-6.1 chr4 GO:0008283 Not Cancer Driver No 38 0.104 325 34 0.105 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0008283 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0008283 Census, Compendium Yes 282 0.114 630 77 0.122 1
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:0008283 Not Cancer Driver No 10 0.079 82 6 0.073 0
NPR3 NPR3 P17342 Atrial natriuretic peptide receptor 3 chr5 GO:0008283 Not Cancer Driver No 95 0.176 58 8 0.138 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0008283 Census Yes 83 0.133 298 37 0.124 0
NRARP NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 GO:0008283 Not Cancer Driver No 9 0.079 11 1 0.091 0
OCA2 OCA2 Q04671 P protein chr15 GO:0008283 Not Cancer Driver No 199 0.237 103 23 0.223 39
OGFOD1 OGFOD1 Q8N543 Prolyl 3-hydroxylase OGFOD1 chr16 GO:0008283 Not Cancer Driver No 44 0.081 156 6 0.038 0
OR51E2_ENST00000641638 OR51E2 Q9H255 Olfactory receptor 51E2 chr11 GO:0008283 Not Cancer Driver No 108 0.338 0 0 0.0 0
ORC3_ENST00000392844 ORC3 Q9UBD5 Origin recognition complex subunit 3 chr6 GO:0008283 Not Cancer Driver No 70 0.098 63 5 0.079 0
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0008283 Not Cancer Driver No 57 0.214 67 17 0.254 0
OSR2_ENST00000522510 OSR2 Q8N2R0 Protein odd-skipped-related 2 chr8 GO:0008283 Not Cancer Driver No 59 0.189 66 13 0.197 0
OTUD6B_ENST00000404789 OTUD6B Q8N6M0 Deubiquitinase OTUD6B chr8 GO:0008283 Not Cancer Driver No 35 0.119 152 18 0.118 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0008283 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAK1IP1 PAK1IP1 Q9NWT1 p21-activated protein kinase-interacting protein 1 chr6 GO:0008283 Not Cancer Driver No 38 0.097 83 6 0.072 0
PAK5 PAK5 Q9P286 Serine/threonine-protein kinase PAK 5 chr20 GO:0008283 Not Cancer Driver No 226 0.314 407 123 0.302 0
PALB2 PALB2 Q86YC2 Partner and localizer of BRCA2 chr16 GO:0008283 Census Yes 124 0.105 769 77 0.1 1
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0008283 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 GO:0008283 Not Cancer Driver No 52 0.119 50 10 0.2 0
PDS5B PDS5B Q9NTI5 Sister chromatid cohesion protein PDS5 homolog B chr13 GO:0008283 Not Cancer Driver No 174 0.12 455 61 0.134 0
PELO PELO Q9BRX2 Protein pelota homolog chr5 GO:0008283 Not Cancer Driver No 38 0.099 67 10 0.149 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0008283 Not Cancer Driver No 109 0.408 142 62 0.437 0
PES1 PES1 O00541 Pescadillo homolog chr22 GO:0008283 Not Cancer Driver No 78 0.133 248 33 0.133 0
PITX2_ENST00000354925 PITX2 Q99697 Pituitary homeobox 2 chr4 GO:0008283 Not Cancer Driver No 74 0.233 185 43 0.232 13
PLCL2 PLCL2 Q9UPR0 Inactive phospholipase C-like protein 2 chr3 GO:0008283 Not Cancer Driver No 185 0.164 274 31 0.113 0
PLXNB2_ENST00000359337 PLXNB2 O15031 Plexin-B2 chr22 GO:0008283 Not Cancer Driver No 273 0.149 304 35 0.115 0
POC1B POC1B Q8TC44 POC1 centriolar protein homolog B chr12 GO:0008283 Not Cancer Driver No 52 0.109 86 8 0.093 1
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 GO:0008283 Not Cancer Driver No 36 0.098 94 13 0.138 0
POLR3G POLR3G O15318 DNA-directed RNA polymerase III subunit RPC7 chr5 GO:0008283 Not Cancer Driver No 28 0.126 187 15 0.08 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0008283 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPP1R8 PPP1R8 Q12972 Nuclear inhibitor of protein phosphatase 1 chr1 GO:0008283 Not Cancer Driver No 24 0.068 251 19 0.076 0
PRDM1 PRDM1 O75626 PR domain zinc finger protein 1 chr6 GO:0008283 Census, Compendium Yes 145 0.176 337 66 0.196 0
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 GO:0008283 Not Cancer Driver No 22 0.111 40 5 0.125 0
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:0008283 Census, Compendium Yes 39 0.102 66 11 0.167 17
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0008283 Not Cancer Driver No 182 0.247 537 141 0.263 0
PSMG1 PSMG1 O95456 Proteasome assembly chaperone 1 chr21 GO:0008283 Not Cancer Driver No 31 0.108 25 1 0.04 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0008283 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 GO:0008283 Not Cancer Driver No 11 0.069 52 3 0.058 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0008283 Not Cancer Driver No 161 0.16 261 37 0.142 0
PURB PURB Q96QR8 Transcriptional activator protein Pur-beta chr7 GO:0008283 Not Cancer Driver No 27 0.087 161 14 0.087 0
RACGAP1_ENST00000454520 RACGAP1 Q9H0H5 Rac GTPase-activating protein 1 chr12 GO:0008283 Not Cancer Driver No 74 0.117 255 27 0.106 0
RAG2 RAG2 P55895 V(D)J recombination-activating protein 2 chr11 GO:0008283 Not Cancer Driver No 118 0.224 85 23 0.271 6
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 GO:0008283 Not Cancer Driver No 26 0.141 14 3 0.214 0
RASGRF1 RASGRF1 Q13972 Ras-specific guanine nucleotide-releasing factor 1 chr15 GO:0008283 Not Cancer Driver No 226 0.178 332 64 0.193 0
RASGRP4_ENST00000587738 RASGRP4 Q8TDF6 RAS guanyl-releasing protein 4 chr19 GO:0008283 Not Cancer Driver No 96 0.143 184 40 0.217 0
RERE RERE Q9P2R6 Arginine-glutamic acid dipeptide repeats protein chr1 GO:0008283 Not Cancer Driver No 196 0.125 1297 167 0.129 0
RHBDF1 RHBDF1 Q96CC6 Inactive rhomboid protein 1 chr16 GO:0008283 Not Cancer Driver No 96 0.112 316 44 0.139 0
RNF43_ENST00000577716 RNF43 Q68DV7 E3 ubiquitin-protein ligase RNF43 chr17 GO:0008283 Census, Compendium Yes 121 0.155 437 54 0.124 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0008283 Not Cancer Driver No 57 0.109 182 17 0.093 4
RPGRIP1 RPGRIP1 Q96KN7 X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 chr14 GO:0008283 Not Cancer Driver No 219 0.17 680 110 0.162 6
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 GO:0008283 Not Cancer Driver No 38 0.153 150 25 0.167 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:0008283 Not Cancer Driver No 94 0.128 178 32 0.18 0
RRN3 RRN3 Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 chr16 GO:0008283 Not Cancer Driver No 66 0.101 115 15 0.13 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0008283 Census, Compendium Yes 81 0.179 360 58 0.161 2
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0008283 Not Cancer Driver No 55 0.091 85 4 0.047 0
SALL4 SALL4 Q9UJQ4 Sal-like protein 4 chr20 GO:0008283 Census, Compendium Yes 238 0.226 738 188 0.255 1
SART3 SART3 Q15020 Squamous cell carcinoma antigen recognized by T-cells 3 chr12 GO:0008283 Not Cancer Driver No 101 0.105 404 45 0.111 0
SBDS SBDS Q9Y3A5 Ribosome maturation protein SBDS chr7 GO:0008283 Census Yes 28 0.112 12 1 0.083 2
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0008283 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SDCBP2_ENST00000360779 SDCBP2 Q9H190 Syntenin-2 chr20 GO:0008283 Not Cancer Driver No 49 0.168 69 9 0.13 0
SDR16C5_ENST00000303749 SDR16C5 Q8N3Y7 Epidermal retinol dehydrogenase 2 chr8 GO:0008283 Not Cancer Driver No 81 0.262 4 0 0.0 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0008283 Not Cancer Driver No 266 0.248 23 4 0.174 0
SERPINB1 SERPINB1 P30740 Leukocyte elastase inhibitor chr6 GO:0008283 Not Cancer Driver No 39 0.103 14 0 0.0 0
SETMAR SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0008283 Not Cancer Driver No 62 0.091 154 12 0.078 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0008283 Not Cancer Driver No 47 0.159 1 0 0.0 0
SH2D2A_ENST00000368199 SH2D2A Q9NP31 SH2 domain-containing protein 2A chr1 GO:0008283 Not Cancer Driver No 51 0.131 272 42 0.154 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0008283 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIDT2_ENST00000620360 SIDT2 Q8NBJ9 SID1 transmembrane family member 2 chr11 GO:0008283 Not Cancer Driver No 113 0.136 23 6 0.261 0
SIX2 SIX2 Q9NPC8 Homeobox protein SIX2 chr2 GO:0008283 Census Yes 53 0.182 151 21 0.139 0
SIX3 SIX3 O95343 Homeobox protein SIX3 chr2 GO:0008283 Not Cancer Driver No 44 0.133 196 22 0.112 32
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0008283 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLC11A1 SLC11A1 P49279 Natural resistance-associated macrophage protein 1 chr2 GO:0008283 Not Cancer Driver No 79 0.144 47 5 0.106 0
SLC39A5 SLC39A5 Q6ZMH5 Zinc transporter ZIP5 chr12 GO:0008283 Not Cancer Driver No 67 0.124 139 18 0.129 1
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0008283 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0008283 Census, Compendium Yes 198 0.359 195 17 0.087 8
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0008283 Not Cancer Driver No 374 0.169 87 10 0.115 0
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0008283 Not Cancer Driver No 61 0.138 368 53 0.144 2
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0008283 Not Cancer Driver No 28 0.059 400 24 0.06 4
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0008283 Compendium Yes 86 0.169 495 82 0.166 18
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 GO:0008283 Not Cancer Driver No 54 0.123 267 32 0.12 30
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0008283 Census Yes 53 0.099 130 11 0.085 1
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0008283 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0008283 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0008283 Census, Compendium Yes 106 0.125 325 44 0.135 0
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0008283 Not Cancer Driver No 59 0.239 58 12 0.207 0
TACC1 TACC1 O75410 Transforming acidic coiled-coil-containing protein 1 chr8 GO:0008283 Not Cancer Driver No 82 0.102 654 69 0.106 0
TACC2_ENST00000334433 TACC2 O95359 Transforming acidic coiled-coil-containing protein 2 chr10 GO:0008283 Not Cancer Driver No 475 0.161 2730 444 0.163 0
TACC3 TACC3 Q9Y6A5 Transforming acidic coiled-coil-containing protein 3 chr4 GO:0008283 Not Cancer Driver No 98 0.117 707 81 0.115 0
TAF8 TAF8 Q7Z7C8 Transcription initiation factor TFIID subunit 8 chr6 GO:0008283 Not Cancer Driver No 35 0.113 255 30 0.118 0
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 GO:0008283 Not Cancer Driver No 45 0.123 203 22 0.108 0
TBCK_ENST00000432496 TBCK Q8TEA7 TBC domain-containing protein kinase-like protein chr4 GO:0008283 Not Cancer Driver No 115 0.129 88 9 0.102 2
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0008283 Not Cancer Driver No 101 0.139 42 5 0.119 12
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0008283 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0008283 Not Cancer Driver No 74 0.104 401 36 0.09 1
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0008283 Not Cancer Driver No 117 0.262 201 54 0.269 2
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0008283 Compendium Yes 68 0.082 102 6 0.059 5
TENM4 TENM4 Q6N022 Teneurin-4 chr11 GO:0008283 Not Cancer Driver No 492 0.178 498 63 0.127 3
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 GO:0008283 Not Cancer Driver No 20 0.125 0 0 0.0 0
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0008283 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFBI TGFBI Q15582 Transforming growth factor-beta-induced protein ig-h3 chr5 GO:0008283 Not Cancer Driver No 108 0.158 58 19 0.328 23
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0008283 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0008283 Not Cancer Driver No 129 0.152 268 41 0.153 0
THPO THPO P40225 Thrombopoietin chr3 GO:0008283 Not Cancer Driver No 63 0.178 163 25 0.153 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0008283 Not Cancer Driver No 292 0.348 0 0 0.0 0
TMEM14B_ENST00000379542 TMEM14B Q9NUH8 Transmembrane protein 14B chr6 GO:0008283 Not Cancer Driver No 13 0.114 0 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0008283 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0008283 Not Cancer Driver No 52 0.164 56 1 0.018 1
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0008283 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0008283 Census, Compendium Yes 229 0.337 398 143 0.359 28
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0008283 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIM71 TRIM71 Q2Q1W2 E3 ubiquitin-protein ligase TRIM71 chr3 GO:0008283 Not Cancer Driver No 124 0.143 163 21 0.129 2
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0008283 Not Cancer Driver No 23 0.114 132 11 0.083 7
TXNRD1 TXNRD1 Q16881 Thioredoxin reductase 1, cytoplasmic chr12 GO:0008283 Not Cancer Driver No 85 0.131 67 9 0.134 0
TYR TYR P14679 Tyrosinase chr11 GO:0008283 Not Cancer Driver No 156 0.295 52 15 0.288 111
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0008283 Not Cancer Driver No 19 0.123 32 4 0.125 0
UCHL1 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 GO:0008283 Not Cancer Driver No 33 0.148 34 7 0.206 4
UNCX UNCX A6NJT0 Homeobox protein unc-4 homolog chr7 GO:0008283 Not Cancer Driver No 28 0.053 410 17 0.041 0
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0008283 Not Cancer Driver No 121 0.14 224 42 0.188 0
USP28 USP28 Q96RU2 Ubiquitin carboxyl-terminal hydrolase 28 chr11 GO:0008283 Not Cancer Driver No 151 0.14 311 25 0.08 0
USPL1 USPL1 Q5W0Q7 SUMO-specific isopeptidase USPL1 chr13 GO:0008283 Not Cancer Driver No 107 0.098 578 55 0.095 0
VEGFD VEGFD O43915 Vascular endothelial growth factor D chrX GO:0008283 Not Cancer Driver No 59 0.167 33 6 0.182 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0008283 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0008283 Not Cancer Driver No 56 0.144 84 16 0.19 2
WNT16 WNT16 Q9UBV4 Protein Wnt-16 chr7 GO:0008283 Not Cancer Driver No 59 0.162 28 9 0.321 0
WNT2 WNT2 P09544 Protein Wnt-2 chr7 GO:0008283 Not Cancer Driver No 85 0.236 11 3 0.273 0
WNT2B WNT2B Q93097 Protein Wnt-2b chr1 GO:0008283 Not Cancer Driver No 72 0.184 27 3 0.111 0
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0008283 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0008283 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0008283 Not Cancer Driver No 30 0.085 39 4 0.103 4
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0008283 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0008283 Not Cancer Driver No 93 0.266 18 9 0.5 4
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0008283 Not Cancer Driver No 55 0.158 11 1 0.091 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0008283 Not Cancer Driver No 87 0.119 118 11 0.093 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0008283 Not Cancer Driver No 51 0.101 489 49 0.1 0
YJEFN3 YJEFN3 A6XGL0 YjeF N-terminal domain-containing protein 3 chr19 GO:0008283 Not Cancer Driver No 35 0.117 56 5 0.089 0
YME1L1 YME1L1 Q96TA2 ATP-dependent zinc metalloprotease YME1L1 chr10 GO:0008283 Not Cancer Driver No 112 0.145 136 14 0.103 1
YPEL5 YPEL5 P62699 Protein yippee-like 5 chr2 GO:0008283 Not Cancer Driver No 19 0.157 10 3 0.3 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0008283 Not Cancer Driver No 67 0.116 376 44 0.117 0
YY1AP1_ENST00000295566 YY1AP1 Q9H869 YY1-associated protein 1 chr1 GO:0008283 Not Cancer Driver No 117 0.147 484 74 0.153 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0008283 Compendium Yes 57 0.169 212 30 0.142 0
ZNF324 ZNF324 O75467 Zinc finger protein 324A chr19 GO:0008283 Not Cancer Driver No 78 0.141 282 38 0.135 0
ZNF503 ZNF503 Q96F45 Zinc finger protein 503 chr10 GO:0008283 Not Cancer Driver No 26 0.04 446 14 0.031 0
ZNRF3 ZNRF3 Q9ULT6 E3 ubiquitin-protein ligase ZNRF3 chr22 GO:0008283 Census, Compendium Yes 94 0.1 510 51 0.1 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0008283 Not Cancer Driver No 38 0.083 291 27 0.093 0