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Total number of protein in "GO:0008092" GO term:  411

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 GO:0008092 Census, Compendium Yes 55 0.108 360 39 0.108 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0008092 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTN1_ENST00000193403 ACTN1 P12814 Alpha-actinin-1 chr14 GO:0008092 Not Cancer Driver No 108 0.121 195 30 0.154 6
ACTN2_ENST00000366578 ACTN2 P35609 Alpha-actinin-2 chr1 GO:0008092 Not Cancer Driver No 227 0.254 131 29 0.221 9
ADD1_ENST00000398129 ADD1 P35611 Alpha-adducin chr4 GO:0008092 Not Cancer Driver No 106 0.144 439 64 0.146 0
ADD2_ENST00000407644 ADD2 P35612 Beta-adducin chr2 GO:0008092 Not Cancer Driver No 157 0.216 423 104 0.246 0
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0008092 Not Cancer Driver No 130 0.118 615 66 0.107 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0008092 Not Cancer Driver No 61 0.148 93 11 0.118 0
ALDOA_ENST00000643777 ALDOA P04075 Fructose-bisphosphate aldolase A chr16 GO:0008092 Not Cancer Driver No 47 0.129 65 9 0.138 3
ALDOB ALDOB P05062 Fructose-bisphosphate aldolase B chr9 GO:0008092 Not Cancer Driver No 91 0.25 34 11 0.324 16
ALDOC_ENST00000395321 ALDOC P09972 Fructose-bisphosphate aldolase C chr17 GO:0008092 Not Cancer Driver No 41 0.113 79 4 0.051 0
ANK1_ENST00000347528 ANK1 P16157 Ankyrin-1 chr8 GO:0008092 Census Yes 405 0.215 810 171 0.211 3
ANK2 ANK2 Q01484 Ankyrin-2 chr4 GO:0008092 Not Cancer Driver No 770 0.195 2844 566 0.199 4
ANK3 ANK3 Q12955 Ankyrin-3 chr10 GO:0008092 Not Cancer Driver No 860 0.196 3054 579 0.19 0
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:0008092 Not Cancer Driver No 52 0.163 83 13 0.157 0
ANKRD23_ENST00000418232 ANKRD23 Q86SG2 Ankyrin repeat domain-containing protein 23 chr2 GO:0008092 Not Cancer Driver No 36 0.118 130 20 0.154 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 GO:0008092 Not Cancer Driver No 49 0.145 20 4 0.2 0
AP000646.1 TBCEL-TECTA A0A2R8YFB7 TBCEL-TECTA readthrough (Fragment) chr11 GO:0008092 Not Cancer Driver No 62 0.13 37 10 0.27 0
AP1AR AP1AR Q63HQ0 AP-1 complex-associated regulatory protein chr4 GO:0008092 Not Cancer Driver No 24 0.079 257 24 0.093 0
AP1G1_ENST00000569748 AP1G1 O43747 AP-1 complex subunit gamma-1 chr16 GO:0008092 Not Cancer Driver No 111 0.135 144 22 0.153 0
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0008092 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APOE APOE P02649 Apolipoprotein E chr19 GO:0008092 Not Cancer Driver No 25 0.079 124 6 0.048 12
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0008092 Not Cancer Driver No 67 0.094 292 31 0.106 1
ARHGEF10_ENST00000398564 ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 chr8 GO:0008092 Census, Compendium Yes 175 0.128 586 78 0.133 1
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 GO:0008092 Not Cancer Driver No 106 0.132 301 39 0.13 0
ARL4C_ENST00000390645 ARL4C P56559 ADP-ribosylation factor-like protein 4C chr2 GO:0008092 Not Cancer Driver No 18 0.094 7 1 0.143 0
ARL8A ARL8A Q96BM9 ADP-ribosylation factor-like protein 8A chr1 GO:0008092 Not Cancer Driver No 23 0.124 0 0 0.0 0
ARL8B ARL8B Q9NVJ2 ADP-ribosylation factor-like protein 8B chr3 GO:0008092 Not Cancer Driver No 28 0.151 0 0 0.0 0
ATCAY ATCAY Q86WG3 Caytaxin chr19 GO:0008092 Not Cancer Driver No 75 0.202 188 38 0.202 1
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0008092 Not Cancer Driver No 168 0.188 341 64 0.188 0
B4GALT1 B4GALT1 P15291 Beta-1,4-galactosyltransferase 1 chr9 GO:0008092 Not Cancer Driver No 38 0.095 129 13 0.101 0
B9D2 B9D2 Q9BPU9 B9 domain-containing protein 2 chr19 GO:0008092 Not Cancer Driver No 36 0.206 4 4 1.0 1
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 GO:0008092 Not Cancer Driver No 17 0.081 112 9 0.08 0
BBS4 BBS4 Q96RK4 Bardet-Biedl syndrome 4 protein chr15 GO:0008092 Not Cancer Driver No 58 0.112 110 16 0.145 9
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0008092 Not Cancer Driver No 134 0.144 417 67 0.161 0
BEX4_ENST00000372691 BEX4 Q9NWD9 Protein BEX4 chrX GO:0008092 Not Cancer Driver No 13 0.108 120 13 0.108 0
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 GO:0008092 Not Cancer Driver No 124 0.127 656 86 0.131 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 GO:0008092 Not Cancer Driver No 115 0.14 546 73 0.134 10
BICDL1 BICDL1 Q6ZP65 BICD family-like cargo adapter 1 chr12 GO:0008092 Not Cancer Driver No 62 0.108 380 45 0.118 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0008092 Not Cancer Driver No 65 0.11 456 42 0.092 5
BLOC1S2 BLOC1S2 Q6QNY1 Biogenesis of lysosome-related organelles complex 1 subunit 2 chr10 GO:0008092 Not Cancer Driver No 17 0.12 34 6 0.176 0
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0008092 Not Cancer Driver No 88 0.208 87 13 0.149 0
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:0008092 Census, Compendium Yes 457 0.134 1542 225 0.146 46
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0008092 Not Cancer Driver No 131 0.168 459 78 0.17 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0008092 Not Cancer Driver No 90 0.122 321 39 0.121 0
C7orf43 TRAPPC14 Q8WVR3 Trafficking protein particle complex subunit 14 chr7 GO:0008092 Not Cancer Driver No 45 0.078 226 17 0.075 0
C9orf24 SMRP1 Q8NCR6 Spermatid-specific manchette-related protein 1 chr9 GO:0008092 Not Cancer Driver No 25 0.095 32 4 0.125 0
CACNA1C CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 GO:0008092 Not Cancer Driver No 455 0.205 744 146 0.196 14
CACNA1D_ENST00000350061 CACNA1D Q01668 Voltage-dependent L-type calcium channel subunit alpha-1D chr3 GO:0008092 Census, Compendium Yes 342 0.158 736 126 0.171 2
CALD1 CALD1 Q05682 Caldesmon chr7 GO:0008092 Not Cancer Driver No 133 0.168 793 133 0.168 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0008092 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0008092 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0008092 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 GO:0008092 Not Cancer Driver No 57 0.114 84 10 0.119 0
CAMSAP1 CAMSAP1 Q5T5Y3 Calmodulin-regulated spectrin-associated protein 1 chr9 GO:0008092 Not Cancer Driver No 208 0.13 1129 158 0.14 0
CAMSAP2 CAMSAP2 Q08AD1 Calmodulin-regulated spectrin-associated protein 2 chr1 GO:0008092 Not Cancer Driver No 176 0.118 1025 127 0.124 0
CAMSAP3_ENST00000160298 CAMSAP3 Q9P1Y5 Calmodulin-regulated spectrin-associated protein 3 chr19 GO:0008092 Not Cancer Driver No 132 0.106 889 81 0.091 0
CAPN10 CAPN10 Q9HC96 Calpain-10 chr2 GO:0008092 Not Cancer Driver No 87 0.129 52 6 0.115 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0008092 Not Cancer Driver No 81 0.116 46 11 0.239 0
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0008092 Not Cancer Driver No 111 0.135 168 11 0.065 52
CASC1_ENST00000320267 DNAI7 Q6TDU7 Dynein axonemal intermediate chain 7 chr12 GO:0008092 Not Cancer Driver No 95 0.133 136 15 0.11 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0008092 Not Cancer Driver No 27 0.179 0 0 0.0 25
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 GO:0008092 Not Cancer Driver No 83 0.153 72 10 0.139 1
CDC42EP3 CDC42EP3 Q9UKI2 Cdc42 effector protein 3 chr2 GO:0008092 Not Cancer Driver No 35 0.138 192 22 0.115 0
CDH1 CDH1 P12830 Cadherin-1 chr16 GO:0008092 Census, Compendium Yes 150 0.17 400 82 0.205 5
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0008092 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0008092 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 GO:0008092 Not Cancer Driver No 217 0.115 1136 128 0.113 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0008092 Not Cancer Driver No 64 0.122 241 25 0.104 0
CENPJ CENPJ Q9HC77 Centromere protein J chr13 GO:0008092 Not Cancer Driver No 176 0.132 1176 158 0.134 1
CEP290 CEP290 O15078 Centrosomal protein of 290 kDa chr12 GO:0008092 Not Cancer Driver No 255 0.103 1421 152 0.107 3
CEP57 CEP57 Q86XR8 Centrosomal protein of 57 kDa chr11 GO:0008092 Not Cancer Driver No 61 0.122 403 50 0.124 0
CEP57L1 CEP57L1 Q8IYX8 Centrosomal protein CEP57L1 chr6 GO:0008092 Not Cancer Driver No 42 0.091 289 24 0.083 0
CEP70_ENST00000484888 CEP70 Q8NHQ1 Centrosomal protein of 70 kDa chr3 GO:0008092 Not Cancer Driver No 79 0.132 223 32 0.143 0
CKAP5 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 GO:0008092 Not Cancer Driver No 198 0.097 634 64 0.101 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:0008092 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0008092 Not Cancer Driver No 158 0.122 676 94 0.139 0
CLIP1 CLIP1 P30622 CAP-Gly domain-containing linker protein 1 chr12 GO:0008092 Census, Compendium Yes 184 0.128 1194 136 0.114 0
CLIP2 CLIP2 Q9UDT6 CAP-Gly domain-containing linker protein 2 chr7 GO:0008092 Not Cancer Driver No 162 0.155 807 127 0.157 0
CLIP3_ENST00000593074 CLIP3 Q96DZ5 CAP-Gly domain-containing linker protein 3 chr19 GO:0008092 Not Cancer Driver No 78 0.143 218 22 0.101 0
CLIP4 CLIP4 Q8N3C7 CAP-Gly domain-containing linker protein 4 chr2 GO:0008092 Not Cancer Driver No 112 0.159 287 61 0.213 0
CLSTN1 CLSTN1 O94985 Calsyntenin-1 chr1 GO:0008092 Not Cancer Driver No 110 0.112 271 22 0.081 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0008092 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNTRL_ENST00000238341 CNTRL Q7Z7A1 Centriolin chr9 GO:0008092 Census Yes 234 0.101 1556 159 0.102 0
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0008092 Not Cancer Driver No 51 0.111 126 15 0.119 1
CORO2B CORO2B Q9UQ03 Coronin-2B chr15 GO:0008092 Not Cancer Driver No 85 0.177 37 7 0.189 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0008092 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRMP1_ENST00000397890 CRMP1 Q14194 Dihydropyrimidinase-related protein 1 chr4 GO:0008092 Not Cancer Driver No 122 0.213 96 15 0.156 0
CROCC CROCC Q5TZA2 Rootletin chr1 GO:0008092 Not Cancer Driver No 254 0.126 1583 184 0.116 0
CSRP1_ENST00000340006 CSRP1 P21291 Cysteine and glycine-rich protein 1 chr1 GO:0008092 Not Cancer Driver No 18 0.093 28 4 0.143 0
CSRP2 CSRP2 Q16527 Cysteine and glycine-rich protein 2 chr12 GO:0008092 Not Cancer Driver No 24 0.124 29 2 0.069 0
CSRP3 CSRP3 P50461 Cysteine and glycine-rich protein 3 chr11 GO:0008092 Not Cancer Driver No 25 0.129 31 1 0.032 2
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0008092 Census Yes 126 0.139 268 35 0.131 4
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0008092 Census, Compendium Yes 62 0.176 5 1 0.2 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0008092 Not Cancer Driver No 102 0.114 485 61 0.126 4
DCDC2 DCDC2 Q9UHG0 Doublecortin domain-containing protein 2 chr6 GO:0008092 Not Cancer Driver No 72 0.151 264 41 0.155 2
DCP1A DCP1A Q9NPI6 mRNA-decapping enzyme 1A chr3 GO:0008092 Not Cancer Driver No 46 0.079 382 31 0.081 0
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 GO:0008092 Census Yes 172 0.135 817 111 0.136 11
DCTN2_ENST00000548249 DCTN2 Q13561 Dynactin subunit 2 chr12 GO:0008092 Not Cancer Driver No 46 0.115 253 32 0.126 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0008092 Census, Compendium Yes 133 0.201 301 47 0.156 18
DES DES P17661 Desmin chr2 GO:0008092 Not Cancer Driver No 71 0.151 264 41 0.155 35
DIP2B DIP2B Q9P265 Disco-interacting protein 2 homolog B chr12 GO:0008092 Not Cancer Driver No 181 0.115 375 49 0.131 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 GO:0008092 Not Cancer Driver No 132 0.155 514 82 0.16 0
DIXDC1 DIXDC1 Q155Q3 Dixin chr11 GO:0008092 Not Cancer Driver No 72 0.105 495 55 0.111 0
DLEC1 DLEC1 Q9Y238 Deleted in lung and esophageal cancer protein 1 chr3 GO:0008092 Not Cancer Driver No 220 0.125 416 66 0.159 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0008092 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0008092 Not Cancer Driver No 116 0.16 232 55 0.237 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 GO:0008092 Not Cancer Driver No 230 0.12 1119 135 0.121 0
DMD DMD P11532 Dystrophin chrX GO:0008092 Not Cancer Driver No 895 0.243 1399 329 0.235 14
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0008092 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNAL1 DNAL1 Q4LDG9 Dynein axonemal light chain 1 chr14 GO:0008092 Not Cancer Driver No 19 0.1 31 2 0.065 1
DPYSL3_ENST00000398514 DPYSL3 Q14195 Dihydropyrimidinase-related protein 3 chr5 GO:0008092 Not Cancer Driver No 93 0.163 128 14 0.109 0
DPYSL4 DPYSL4 O14531 Dihydropyrimidinase-related protein 4 chr10 GO:0008092 Not Cancer Driver No 105 0.184 102 15 0.147 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:0008092 Not Cancer Driver No 21 0.114 4 1 0.25 0
DYNC1I1 DYNC1I1 O14576 Cytoplasmic dynein 1 intermediate chain 1 chr7 GO:0008092 Not Cancer Driver No 146 0.226 255 60 0.235 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0008092 Not Cancer Driver No 135 0.177 447 73 0.163 0
EFHC1 EFHC1 Q5JVL4 EF-hand domain-containing protein 1 chr6 GO:0008092 Not Cancer Driver No 79 0.123 78 15 0.192 17
EFHC2 EFHC2 Q5JST6 EF-hand domain-containing family member C2 chrX GO:0008092 Not Cancer Driver No 113 0.151 50 10 0.2 0
EMD EMD P50402 Emerin chrX GO:0008092 Not Cancer Driver No 42 0.165 160 28 0.175 4
EML4 EML4 Q9HC35 Echinoderm microtubule-associated protein-like 4 chr2 GO:0008092 Census, Compendium Yes 105 0.107 385 41 0.106 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0008092 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPB41L2_ENST00000368128 EPB41L2 O43491 Band 4.1-like protein 2 chr6 GO:0008092 Not Cancer Driver No 157 0.156 708 113 0.16 0
EPB41L4A_ENST00000621003 EPB41L4A Q9HCS5 Band 4.1-like protein 4A chr5 GO:0008092 Not Cancer Driver No 119 0.173 378 65 0.172 0
EPB41L4B EPB41L4B Q9H329 Band 4.1-like protein 4B chr9 GO:0008092 Not Cancer Driver No 131 0.146 548 77 0.141 0
EPB41L5 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 GO:0008092 Not Cancer Driver No 97 0.132 312 45 0.144 0
EPB41_ENST00000373798 EPB41 P11171 Protein 4.1 chr1 GO:0008092 Not Cancer Driver No 101 0.117 557 69 0.124 0
FABP3 FABP3 P05413 Fatty acid-binding protein, heart chr1 GO:0008092 Not Cancer Driver No 22 0.165 3 0 0.0 0
FAM110C FAM110C Q1W6H9 Protein FAM110C chr2 GO:0008092 Not Cancer Driver No 33 0.103 286 32 0.112 0
FAM83D FAM83D Q9H4H8 Protein FAM83D chr20 GO:0008092 Not Cancer Driver No 70 0.12 273 29 0.106 0
FARP1_ENST00000319562 FARP1 Q9Y4F1 FERM, ARHGEF and pleckstrin domain-containing protein 1 chr13 GO:0008092 Not Cancer Driver No 147 0.141 315 60 0.19 0
FARP2 FARP2 O94887 FERM, ARHGEF and pleckstrin domain-containing protein 2 chr2 GO:0008092 Not Cancer Driver No 133 0.126 250 39 0.156 0
FBLIM1_ENST00000375771 FBLIM1 Q8WUP2 Filamin-binding LIM protein 1 chr1 GO:0008092 Not Cancer Driver No 54 0.145 176 28 0.159 0
FBXW11 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 GO:0008092 Not Cancer Driver No 75 0.138 20 3 0.15 7
FEZ1 FEZ1 Q99689 Fasciculation and elongation protein zeta-1 chr11 GO:0008092 Not Cancer Driver No 66 0.168 277 49 0.177 0
FGF13_ENST00000315930 FGF13 Q92913 Fibroblast growth factor 13 chrX GO:0008092 Not Cancer Driver No 70 0.286 96 33 0.344 2
FKBP4 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 GO:0008092 Not Cancer Driver No 46 0.1 134 12 0.09 0
FLNC FLNC Q14315 Filamin-C chr7 GO:0008092 Not Cancer Driver No 546 0.2 1442 288 0.2 7
FNTA FNTA P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha chr8 GO:0008092 Not Cancer Driver No 43 0.113 92 12 0.13 0
FRMD3 FRMD3 A2A2Y4 FERM domain-containing protein 3 chr9 GO:0008092 Not Cancer Driver No 110 0.184 131 27 0.206 0
FRMD5 FRMD5 Q7Z6J6 FERM domain-containing protein 5 chr15 GO:0008092 Not Cancer Driver No 69 0.121 134 20 0.149 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0008092 Not Cancer Driver No 92 0.171 70 13 0.186 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 GO:0008092 Not Cancer Driver No 9 0.077 11 0 0.0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 GO:0008092 Not Cancer Driver No 19 0.162 10 1 0.1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 GO:0008092 Not Cancer Driver No 11 0.094 2 1 0.5 0
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0008092 Not Cancer Driver No 92 0.155 166 27 0.163 0
GCSAM_ENST00000308910 GCSAM Q8N6F7 Germinal center-associated signaling and motility protein chr3 GO:0008092 Not Cancer Driver No 31 0.174 136 22 0.162 0
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0008092 Not Cancer Driver No 67 0.088 434 42 0.097 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0008092 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJB6_ENST00000644667 GJB6 O95452 Gap junction beta-6 protein chr13 GO:0008092 Not Cancer Driver No 42 0.161 12 4 0.333 4
GNB3 GNB3 P16520 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 chr12 GO:0008092 Not Cancer Driver No 51 0.15 13 1 0.077 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0008092 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0008092 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSN GSN P06396 Gelsolin chr9 GO:0008092 Not Cancer Driver No 76 0.097 316 28 0.089 2
HAUS4 HAUS4 Q9H6D7 HAUS augmin-like complex subunit 4 chr14 GO:0008092 Not Cancer Driver No 42 0.116 2 0 0.0 0
HAUS7 HAUS7 Q99871 HAUS augmin-like complex subunit 7 chrX GO:0008092 Not Cancer Driver No 51 0.142 78 7 0.09 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0008092 Not Cancer Driver No 178 0.147 409 59 0.144 0
HOOK3 HOOK3 Q86VS8 Protein Hook homolog 3 chr8 GO:0008092 Census Yes 79 0.11 493 55 0.112 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0008092 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0008092 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 GO:0008092 Not Cancer Driver No 93 0.146 286 38 0.133 0
HSPB7 HSPB7 Q9UBY9 Heat shock protein beta-7 chr1 GO:0008092 Not Cancer Driver No 21 0.124 153 19 0.124 0
HSPH1_ENST00000320027 HSPH1 Q92598 Heat shock protein 105 kDa chr13 GO:0008092 Not Cancer Driver No 103 0.12 323 42 0.13 0
HTT HTT P42858 Huntingtin chr4 GO:0008092 Not Cancer Driver No 336 0.107 666 69 0.104 2
IFT74_ENST00000433700 IFT74 Q96LB3 Intraflagellar transport protein 74 homolog chr9 GO:0008092 Not Cancer Driver No 47 0.078 490 38 0.078 0
IFT88_ENST00000351808 IFT88 Q13099 Intraflagellar transport protein 88 homolog chr13 GO:0008092 Not Cancer Driver No 99 0.12 280 30 0.107 0
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0008092 Compendium Yes 173 0.111 682 76 0.111 0
IQGAP3 IQGAP3 Q86VI3 Ras GTPase-activating-like protein IQGAP3 chr1 GO:0008092 Not Cancer Driver No 233 0.143 257 36 0.14 0
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 GO:0008092 Not Cancer Driver No 96 0.192 82 16 0.195 5
KCNA5 KCNA5 P22460 Potassium voltage-gated channel subfamily A member 5 chr12 GO:0008092 Not Cancer Driver No 213 0.347 218 53 0.243 0
KCNC1_ENST00000379472 KCNC1 P48547 Potassium voltage-gated channel subfamily C member 1 chr11 GO:0008092 Not Cancer Driver No 91 0.178 110 18 0.164 1
KCNE1_ENST00000399284 KCNE1 P15382 Potassium voltage-gated channel subfamily E member 1 chr21 GO:0008092 Not Cancer Driver No 35 0.271 24 10 0.417 9
KCNJ11 KCNJ11 Q14654 ATP-sensitive inward rectifier potassium channel 11 chr11 GO:0008092 Not Cancer Driver No 48 0.123 19 3 0.158 46
KCNN2 KCNN2 Q9H2S1 Small conductance calcium-activated potassium channel protein 2 chr5 GO:0008092 Not Cancer Driver No 112 0.193 175 33 0.189 0
KCNQ2 KCNQ2 O43526 Potassium voltage-gated channel subfamily KQT member 2 chr20 GO:0008092 Not Cancer Driver No 171 0.196 393 81 0.206 37
KCTD6_ENST00000490264 KCTD6 Q8NC69 BTB/POZ domain-containing protein KCTD6 chr3 GO:0008092 Not Cancer Driver No 27 0.114 12 1 0.083 0
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 GO:0008092 Not Cancer Driver No 114 0.127 405 60 0.148 0
KIF18B KIF18B Q86Y91 Kinesin-like protein KIF18B chr17 GO:0008092 Not Cancer Driver No 100 0.117 590 69 0.117 0
KIF1BP KIFBP Q96EK5 KIF-binding protein chr10 GO:0008092 Not Cancer Driver No 63 0.101 98 18 0.184 0
KIF1B_ENST00000377086 KIF1B O60333 Kinesin-like protein KIF1B chr1 GO:0008092 Not Cancer Driver No 253 0.139 633 106 0.167 1
KIF2C KIF2C Q99661 Kinesin-like protein KIF2C chr1 GO:0008092 Not Cancer Driver No 110 0.152 337 63 0.187 0
KIF3A_ENST00000378746 KIF3A Q9Y496 Kinesin-like protein KIF3A chr5 GO:0008092 Not Cancer Driver No 92 0.132 409 59 0.144 0
KIF5A KIF5A Q12840 Kinesin heavy chain isoform 5A chr12 GO:0008092 Not Cancer Driver No 194 0.188 569 103 0.181 14
KIFAP3 KIFAP3 Q92845 Kinesin-associated protein 3 chr1 GO:0008092 Not Cancer Driver No 116 0.146 71 10 0.141 0
KLC1_ENST00000348520 KLC1 Q07866 Kinesin light chain 1 chr14 GO:0008092 Not Cancer Driver No 54 0.094 292 31 0.106 0
KLC2_ENST00000394067 KLC2 Q9H0B6 Kinesin light chain 2 chr11 GO:0008092 Not Cancer Driver No 75 0.121 344 49 0.142 0
KLC3 KLC3 Q6P597 Kinesin light chain 3 chr19 GO:0008092 Not Cancer Driver No 52 0.103 338 32 0.095 0
KLC4_ENST00000479388 KLC4 Q9NSK0 Kinesin light chain 4 chr6 GO:0008092 Not Cancer Driver No 82 0.132 383 53 0.138 0
KNSTRN KNSTRN Q9Y448 Small kinetochore-associated protein chr15 GO:0008092 Census Yes 75 0.237 246 67 0.272 0
KRT2 KRT2 P35908 Keratin, type II cytoskeletal 2 epidermal chr12 GO:0008092 Not Cancer Driver No 122 0.191 335 59 0.176 15
KTN1 KTN1 Q86UP2 Kinectin chr14 GO:0008092 Census Yes 138 0.102 964 102 0.106 0
LDB3_ENST00000361373 LDB3 O75112 LIM domain-binding protein 3 chr10 GO:0008092 Not Cancer Driver No 107 0.147 529 71 0.134 4
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0008092 Not Cancer Driver No 57 0.132 112 19 0.17 0
LIMCH1_ENST00000313860 LIMCH1 Q9UPQ0 LIM and calponin homology domains-containing protein 1 chr4 GO:0008092 Not Cancer Driver No 177 0.163 880 140 0.159 0
LIN7C LIN7C Q9NUP9 Protein lin-7 homolog C chr11 GO:0008092 Not Cancer Driver No 22 0.112 102 11 0.108 0
LLGL1 LLGL1 Q15334 Lethal(2) giant larvae protein homolog 1 chr17 GO:0008092 Not Cancer Driver No 101 0.095 265 12 0.045 0
LLGL2 LLGL2 Q6P1M3 LLGL scribble cell polarity complex component 2 chr17 GO:0008092 Not Cancer Driver No 120 0.118 266 26 0.098 0
LMOD1 LMOD1 P29536 Leiomodin-1 chr1 GO:0008092 Not Cancer Driver No 97 0.162 499 80 0.16 0
LMOD2 LMOD2 Q6P5Q4 Leiomodin-2 chr7 GO:0008092 Not Cancer Driver No 94 0.172 451 79 0.175 0
LMOD3_ENST00000489031 LMOD3 Q0VAK6 Leiomodin-3 chr3 GO:0008092 Not Cancer Driver No 99 0.177 456 84 0.184 1
LMTK2 LMTK2 Q8IWU2 Serine/threonine-protein kinase LMTK2 chr7 GO:0008092 Not Cancer Driver No 211 0.14 1018 141 0.139 0
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0008092 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 GO:0008092 Not Cancer Driver No 131 0.094 18 2 0.111 1
LRRC10 LRRC10 Q5BKY1 Leucine-rich repeat-containing protein 10 chr12 GO:0008092 Not Cancer Driver No 52 0.188 38 11 0.289 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0008092 Census Yes 95 0.186 84 12 0.143 0
MACF1_ENST00000372915 MACF1 Q9UPN3 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 chr1 GO:0008092 Not Cancer Driver No 877 0.119 2826 334 0.118 4
MAGI1 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 GO:0008092 Not Cancer Driver No 260 0.174 1212 220 0.182 0
MAP1A MAP1A P78559 Microtubule-associated protein 1A chr15 GO:0008092 Not Cancer Driver No 369 0.132 2443 311 0.127 0
MAP1S MAP1S Q66K74 Microtubule-associated protein 1S chr19 GO:0008092 Not Cancer Driver No 118 0.111 527 48 0.091 0
MAP2 MAP2 P11137 Microtubule-associated protein 2 chr2 GO:0008092 Compendium Yes 367 0.201 1726 340 0.197 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:0008092 Not Cancer Driver No 79 0.111 444 40 0.09 1
MAPK8IP2 MAPK8IP2 Q13387 C-Jun-amino-terminal kinase-interacting protein 2 chr22 GO:0008092 Not Cancer Driver No 49 0.059 568 27 0.048 0
MAPK8IP3_ENST00000250894 MAPK8IP3 Q9UPT6 C-Jun-amino-terminal kinase-interacting protein 3 chr16 GO:0008092 Not Cancer Driver No 179 0.134 746 110 0.147 3
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 GO:0008092 Not Cancer Driver No 26 0.097 109 11 0.101 0
MAPRE2 MAPRE2 Q15555 Microtubule-associated protein RP/EB family member 2 chr18 GO:0008092 Not Cancer Driver No 50 0.153 176 28 0.159 3
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 GO:0008092 Not Cancer Driver No 37 0.132 120 16 0.133 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0008092 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARK1_ENST00000366917 MARK1 Q9P0L2 Serine/threonine-protein kinase MARK1 chr1 GO:0008092 Not Cancer Driver No 161 0.203 454 108 0.238 0
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 GO:0008092 Compendium Yes 124 0.157 445 70 0.157 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 GO:0008092 Not Cancer Driver No 92 0.122 376 49 0.13 1
MARK4 MARK4 Q96L34 MAP/microtubule affinity-regulating kinase 4 chr19 GO:0008092 Not Cancer Driver No 94 0.125 403 46 0.114 0
MICALL2 MICALL2 Q8IY33 MICAL-like protein 2 chr7 GO:0008092 Not Cancer Driver No 110 0.122 675 88 0.13 0
MYBPC1_ENST00000550270 MYBPC1 Q00872 Myosin-binding protein C, slow-type chr12 GO:0008092 Not Cancer Driver No 227 0.199 220 38 0.173 7
MYBPC3 MYBPC3 Q14896 Myosin-binding protein C, cardiac-type chr11 GO:0008092 Not Cancer Driver No 178 0.14 434 62 0.143 64
MYH8 MYH8 P13535 Myosin-8 chr17 GO:0008092 Not Cancer Driver No 498 0.257 1086 315 0.29 2
MYL12A_ENST00000217652 MYL12A P19105 Myosin regulatory light chain 12A chr18 GO:0008092 Not Cancer Driver No 19 0.111 70 13 0.186 0
MYL12B_ENST00000237500 MYL12B O14950 Myosin regulatory light chain 12B chr18 GO:0008092 Not Cancer Driver No 23 0.134 61 13 0.213 0
MYL2 MYL2 P10916 Myosin regulatory light chain 2, ventricular/cardiac muscle isoform chr12 GO:0008092 Not Cancer Driver No 44 0.265 34 8 0.235 6
MYL3 MYL3 P08590 Myosin light chain 3 chr3 GO:0008092 Not Cancer Driver No 21 0.108 99 9 0.091 5
MYL4_ENST00000572316 MYL4 P12829 Myosin light chain 4 chr17 GO:0008092 Not Cancer Driver No 29 0.147 104 11 0.106 1
MYL9 MYL9 P24844 Myosin regulatory light polypeptide 9 chr20 GO:0008092 Not Cancer Driver No 34 0.198 82 19 0.232 0
MYLIP MYLIP Q8WY64 E3 ubiquitin-protein ligase MYLIP chr6 GO:0008092 Not Cancer Driver No 56 0.126 11 2 0.182 0
MYLK2 MYLK2 Q9H1R3 Myosin light chain kinase 2, skeletal/cardiac muscle chr20 GO:0008092 Not Cancer Driver No 118 0.198 277 64 0.231 2
MYO10 MYO10 Q9HD67 Unconventional myosin-X chr5 GO:0008092 Not Cancer Driver No 296 0.144 418 59 0.141 0
MYO7A MYO7A Q13402 Unconventional myosin-VIIa chr11 GO:0008092 Not Cancer Driver No 298 0.135 369 58 0.157 50
MYOC MYOC Q99972 Myocilin chr1 GO:0008092 Not Cancer Driver No 92 0.183 196 43 0.219 58
MYOT MYOT Q9UBF9 Myotilin chr5 GO:0008092 Not Cancer Driver No 78 0.157 280 39 0.139 6
MYOZ1 MYOZ1 Q9NP98 Myozenin-1 chr10 GO:0008092 Not Cancer Driver No 49 0.164 223 39 0.175 0
MYOZ2 MYOZ2 Q9NPC6 Myozenin-2 chr4 GO:0008092 Not Cancer Driver No 50 0.189 197 38 0.193 2
MYOZ3_ENST00000517768 MYOZ3 Q8TDC0 Myozenin-3 chr5 GO:0008092 Not Cancer Driver No 40 0.159 211 27 0.128 0
MYPN_ENST00000540630 MYPN Q86TC9 Myopalladin chr10 GO:0008092 Not Cancer Driver No 262 0.198 925 182 0.197 17
NCALD NCALD P61601 Neurocalcin-delta chr8 GO:0008092 Not Cancer Driver No 37 0.192 34 4 0.118 0
NCKIPSD NCKIPSD Q9NZQ3 NCK-interacting protein with SH3 domain chr3 GO:0008092 Census Yes 63 0.087 260 28 0.108 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0008092 Not Cancer Driver No 32 0.093 202 16 0.079 0
NDN NDN Q99608 Necdin chr15 GO:0008092 Not Cancer Driver No 123 0.383 117 42 0.359 0
NDRG1 NDRG1 Q92597 Protein NDRG1 chr8 GO:0008092 Census Yes 66 0.168 140 22 0.157 0
NEBL NEBL O76041 Nebulette chr10 GO:0008092 Not Cancer Driver No 239 0.236 773 183 0.237 0
NEDD1_ENST00000266742 NEDD1 Q8NHV4 Protein NEDD1 chr12 GO:0008092 Not Cancer Driver No 87 0.132 282 36 0.128 0
NEFH NEFH P12036 Neurofilament heavy polypeptide chr22 GO:0008092 Compendium Yes 114 0.111 871 106 0.122 0
NEK6_ENST00000545174 NEK6 Q9HC98 Serine/threonine-protein kinase Nek6 chr9 GO:0008092 Not Cancer Driver No 31 0.099 36 0 0.0 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0008092 Not Cancer Driver No 104 0.107 344 38 0.11 0
NIN NIN Q8N4C6 Ninein chr14 GO:0008092 Census, Compendium Yes 239 0.114 1392 164 0.118 2
NKD2 NKD2 Q969F2 Protein naked cuticle homolog 2 chr5 GO:0008092 Not Cancer Driver No 64 0.142 451 64 0.142 0
NPC1L1 NPC1L1 Q9UHC9 NPC1-like intracellular cholesterol transporter 1 chr7 GO:0008092 Not Cancer Driver No 222 0.163 8 2 0.25 0
NRAP_ENST00000359988 NRAP Q86VF7 Nebulin-related-anchoring protein chr10 GO:0008092 Not Cancer Driver No 302 0.175 706 139 0.197 0
NRCAM_ENST00000425651 NRCAM Q92823 Neuronal cell adhesion molecule chr7 GO:0008092 Not Cancer Driver No 210 0.161 471 75 0.159 0
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 GO:0008092 Census, Compendium Yes 234 0.111 1864 203 0.109 0
OBSCN_ENST00000422127 OBSCN Q5VST9 Obscurin chr1 GO:0008092 Not Cancer Driver No 1208 0.152 2623 368 0.14 0
OFD1 OFD1 O75665 Oral-facial-digital syndrome 1 protein chrX GO:0008092 Not Cancer Driver No 129 0.127 476 58 0.122 5
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0008092 Not Cancer Driver No 107 0.268 58 27 0.466 0
PACRG PACRG Q96M98 Parkin coregulated gene protein chr6 GO:0008092 Not Cancer Driver No 66 0.223 45 6 0.133 0
PACSIN1_ENST00000244458 PACSIN1 Q9BY11 Protein kinase C and casein kinase substrate in neurons protein 1 chr6 GO:0008092 Not Cancer Driver No 56 0.126 318 47 0.148 0
PACSIN2_ENST00000402229 PACSIN2 Q9UNF0 Protein kinase C and casein kinase substrate in neurons protein 2 chr22 GO:0008092 Not Cancer Driver No 51 0.105 301 27 0.09 0
PACSIN3_ENST00000298838 PACSIN3 Q9UKS6 Protein kinase C and casein kinase substrate in neurons protein 3 chr11 GO:0008092 Not Cancer Driver No 52 0.123 290 31 0.107 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0008092 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0008092 Not Cancer Driver No 57 0.105 299 30 0.1 2
PDCD5 PDCD5 O14737 Programmed cell death protein 5 chr19 GO:0008092 Not Cancer Driver No 15 0.12 91 7 0.077 0
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0008092 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDE6G PDE6G P18545 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma chr17 GO:0008092 Not Cancer Driver No 15 0.172 58 11 0.19 0
PDLIM1 PDLIM1 O00151 PDZ and LIM domain protein 1 chr10 GO:0008092 Not Cancer Driver No 62 0.188 219 39 0.178 0
PDLIM2_ENST00000409417 PDLIM2 Q96JY6 PDZ and LIM domain protein 2 chr8 GO:0008092 Not Cancer Driver No 52 0.148 288 44 0.153 0
PDLIM3 PDLIM3 Q53GG5 PDZ and LIM domain protein 3 chr4 GO:0008092 Not Cancer Driver No 44 0.121 235 35 0.149 0
PDLIM4 PDLIM4 P50479 PDZ and LIM domain protein 4 chr5 GO:0008092 Not Cancer Driver No 42 0.127 238 28 0.118 0
PDLIM5_ENST00000317968 PDLIM5 Q96HC4 PDZ and LIM domain protein 5 chr4 GO:0008092 Not Cancer Driver No 89 0.149 372 57 0.153 0
PDLIM7 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 GO:0008092 Not Cancer Driver No 48 0.105 244 20 0.082 0
PEX14 PEX14 O75381 Peroxisomal membrane protein PEX14 chr1 GO:0008092 Not Cancer Driver No 38 0.101 266 28 0.105 0
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0008092 Census Yes 89 0.137 320 42 0.131 0
PIFO PIFO Q8TCI5 Protein pitchfork chr1 GO:0008092 Not Cancer Driver No 31 0.162 70 11 0.157 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0008092 Not Cancer Driver No 17 0.104 115 12 0.104 0
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0008092 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKD2L1 PKD2L1 Q9P0L9 Polycystic kidney disease 2-like 1 protein chr10 GO:0008092 Not Cancer Driver No 135 0.168 180 32 0.178 0
PLEC PLEC Q15149 Plectin chr8 GO:0008092 Not Cancer Driver No 677 0.145 2130 272 0.128 2
PLEKHM2 PLEKHM2 Q8IWE5 Pleckstrin homology domain-containing family M member 2 chr1 GO:0008092 Not Cancer Driver No 96 0.094 392 35 0.089 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0008092 Census Yes 72 0.143 44 4 0.091 3
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 GO:0008092 Not Cancer Driver No 41 0.133 12 1 0.083 8
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 GO:0008092 Not Cancer Driver No 37 0.12 12 0 0.0 0
PPP5C PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 GO:0008092 Not Cancer Driver No 70 0.14 73 12 0.164 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 GO:0008092 Not Cancer Driver No 63 0.102 235 26 0.111 0
PRICKLE4_ENST00000394260 PRICKLE4 Q2TBC4 Prickle-like protein 4 chr6 GO:0008092 Not Cancer Driver No 44 0.128 130 15 0.115 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0008092 Not Cancer Driver No 72 0.129 124 17 0.137 0
PROM1 PROM1 O43490 Prominin-1 chr4 GO:0008092 Not Cancer Driver No 94 0.109 76 9 0.118 3
PTPN3 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 GO:0008092 Not Cancer Driver No 139 0.152 214 28 0.131 0
PTPN4 PTPN4 P29074 Tyrosine-protein phosphatase non-receptor type 4 chr2 GO:0008092 Not Cancer Driver No 132 0.143 263 32 0.122 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0008092 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRN PTPRN Q16849 Receptor-type tyrosine-protein phosphatase-like N chr2 GO:0008092 Not Cancer Driver No 142 0.145 498 73 0.147 0
PTPRT_ENST00000373187 PTPRT O14522 Receptor-type tyrosine-protein phosphatase T chr20 GO:0008092 Census, Compendium Yes 535 0.371 299 125 0.418 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 GO:0008092 Not Cancer Driver No 62 0.105 341 24 0.07 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0008092 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAB10 RAB10 P61026 Ras-related protein Rab-10 chr2 GO:0008092 Not Cancer Driver No 19 0.095 28 2 0.071 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0008092 Not Cancer Driver No 31 0.144 43 4 0.093 0
RAB11B RAB11B Q15907 Ras-related protein Rab-11B chr19 GO:0008092 Not Cancer Driver No 26 0.119 39 3 0.077 2
RAB11FIP5 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 GO:0008092 Not Cancer Driver No 83 0.127 533 70 0.131 0
RAB14 RAB14 P61106 Ras-related protein Rab-14 chr9 GO:0008092 Not Cancer Driver No 20 0.093 41 4 0.098 0
RAB25 RAB25 P57735 Ras-related protein Rab-25 chr1 GO:0008092 Not Cancer Driver No 26 0.122 32 5 0.156 0
RAB27A_ENST00000336787 RAB27A P51159 Ras-related protein Rab-27A chr15 GO:0008092 Not Cancer Driver No 25 0.113 15 4 0.267 3
RAB27B RAB27B O00194 Ras-related protein Rab-27B chr18 GO:0008092 Not Cancer Driver No 42 0.193 43 9 0.209 0
RAB29 RAB29 O14966 Ras-related protein Rab-7L1 chr1 GO:0008092 Not Cancer Driver No 28 0.138 18 3 0.167 0
RAB39B RAB39B Q96DA2 Ras-related protein Rab-39B chrX GO:0008092 Not Cancer Driver No 45 0.211 0 0 0.0 2
RAB3A RAB3A P20336 Ras-related protein Rab-3A chr19 GO:0008092 Not Cancer Driver No 25 0.114 43 4 0.093 0
RAB3B RAB3B P20337 Ras-related protein Rab-3B chr1 GO:0008092 Not Cancer Driver No 36 0.164 25 6 0.24 0
RAB3C RAB3C Q96E17 Ras-related protein Rab-3C chr5 GO:0008092 Not Cancer Driver No 52 0.229 54 10 0.185 0
RAB3D_ENST00000589655 RAB3D O95716 Ras-related protein Rab-3D chr19 GO:0008092 Not Cancer Driver No 37 0.169 46 6 0.13 0
RAB6A_ENST00000336083 RAB6A P20340 Ras-related protein Rab-6A chr11 GO:0008092 Not Cancer Driver No 22 0.106 45 6 0.133 0
RAB6B RAB6B Q9NRW1 Ras-related protein Rab-6B chr3 GO:0008092 Not Cancer Driver No 39 0.188 42 5 0.119 0
RAB8A RAB8A P61006 Ras-related protein Rab-8A chr19 GO:0008092 Not Cancer Driver No 37 0.179 26 3 0.115 0
RACGAP1_ENST00000454520 RACGAP1 Q9H0H5 Rac GTPase-activating protein 1 chr12 GO:0008092 Not Cancer Driver No 74 0.117 255 27 0.106 0
RAD51D_ENST00000394589 RAD51D O75771 DNA repair protein RAD51 homolog 4 chr17 GO:0008092 Not Cancer Driver No 34 0.104 49 10 0.204 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0008092 Census, Compendium Yes 70 0.152 167 14 0.084 0
RCAN3_ENST00000538532 RCAN3 Q9UKA8 Calcipressin-3 chr1 GO:0008092 Not Cancer Driver No 34 0.141 121 18 0.149 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0008092 Compendium Yes 75 0.136 400 48 0.12 0
RFLNA_ENST00000546355 RFLNA Q6ZTI6 Refilin-A chr12 GO:0008092 Not Cancer Driver No 23 0.106 122 8 0.066 0
RGS2 RGS2 P41220 Regulator of G-protein signaling 2 chr1 GO:0008092 Not Cancer Driver No 30 0.142 50 4 0.08 0
RHAG RHAG Q02094 Ammonium transporter Rh type A chr6 GO:0008092 Not Cancer Driver No 102 0.249 0 0 0.0 6
RHBG RHBG Q9H310 Ammonium transporter Rh type B chr1 GO:0008092 Not Cancer Driver No 66 0.144 32 7 0.219 0
RHCG RHCG Q9UBD6 Ammonium transporter Rh type C chr15 GO:0008092 Not Cancer Driver No 74 0.154 19 2 0.105 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0008092 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0008092 Not Cancer Driver No 145 0.104 732 81 0.111 0
RPH3AL RPH3AL Q9UNE2 Rab effector Noc2 chr17 GO:0008092 Not Cancer Driver No 40 0.127 162 20 0.123 0
RTCB RTCB Q9Y3I0 RNA-splicing ligase RtcB homolog chr22 GO:0008092 Not Cancer Driver No 57 0.113 74 7 0.095 0
S100A6_ENST00000496817 S100A6 P06703 Protein S100-A6 chr1 GO:0008092 Not Cancer Driver No 5 0.056 4 0 0.0 0
S100B S100B P04271 Protein S100-B chr21 GO:0008092 Not Cancer Driver No 17 0.185 13 1 0.077 0
SCN5A_ENST00000333535 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 GO:0008092 Not Cancer Driver No 491 0.244 550 144 0.262 190
SETD2 SETD2 Q9BYW2 Histone-lysine N-methyltransferase SETD2 chr3 GO:0008092 Census, Compendium Yes 321 0.125 1945 209 0.107 2
SHROOM1 SHROOM1 Q2M3G4 Protein Shroom1 chr5 GO:0008092 Not Cancer Driver No 70 0.082 712 57 0.08 0
SHROOM4 SHROOM4 Q9ULL8 Protein Shroom4 chrX GO:0008092 Not Cancer Driver No 242 0.162 1027 167 0.163 1
SHTN1 SHTN1 A0MZ66 Shootin-1 chr10 GO:0008092 Census Yes 68 0.108 470 52 0.111 0
SLC26A5 SLC26A5 P58743 Prestin chr7 GO:0008092 Not Cancer Driver No 135 0.181 59 11 0.186 0
SLC4A1 SLC4A1 P02730 Band 3 anion transport protein chr17 GO:0008092 Not Cancer Driver No 153 0.168 130 23 0.177 39
SLC6A2_ENST00000568943 SLC6A2 P23975 Sodium-dependent noradrenaline transporter chr16 GO:0008092 Not Cancer Driver No 127 0.206 23 8 0.348 1
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0008092 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0008092 Not Cancer Driver No 19 0.053 318 16 0.05 4
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0008092 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0008092 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMC3 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 GO:0008092 Not Cancer Driver No 149 0.122 605 70 0.116 0
SMTNL1 SMTNL1 A8MU46 Smoothelin-like protein 1 chr11 GO:0008092 Not Cancer Driver No 80 0.162 372 54 0.145 0
SMTNL2 SMTNL2 Q2TAL5 Smoothelin-like protein 2 chr17 GO:0008092 Not Cancer Driver No 45 0.098 344 33 0.096 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0008092 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNX5_ENST00000377759 SNX5 Q9Y5X3 Sorting nexin-5 chr20 GO:0008092 Not Cancer Driver No 33 0.082 91 13 0.143 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:0008092 Not Cancer Driver No 33 0.081 85 7 0.082 0
SORBS1_ENST00000361941 SORBS1 Q9BX66 Sorbin and SH3 domain-containing protein 1 chr10 GO:0008092 Not Cancer Driver No 161 0.125 1111 133 0.12 0
SORBS3 SORBS3 O60504 Vinexin chr8 GO:0008092 Not Cancer Driver No 62 0.092 577 56 0.097 0
SPAG9 SPAG9 O60271 C-Jun-amino-terminal kinase-interacting protein 4 chr17 GO:0008092 Not Cancer Driver No 128 0.097 841 81 0.096 0
SPAST SPAST Q9UBP0 Spastin chr2 GO:0008092 Not Cancer Driver No 73 0.119 270 25 0.093 77
SPATA6 SPATA6 Q9NWH7 Spermatogenesis-associated protein 6 chr1 GO:0008092 Not Cancer Driver No 63 0.129 278 38 0.137 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 GO:0008092 Not Cancer Driver No 311 0.132 869 123 0.142 0
SPTBN4_ENST00000598249 SPTBN4 Q9H254 Spectrin beta chain, non-erythrocytic 4 chr19 GO:0008092 Not Cancer Driver No 312 0.122 866 103 0.119 0
SPTBN5 SPTBN5 Q9NRC6 Spectrin beta chain, non-erythrocytic 5 chr15 GO:0008092 Not Cancer Driver No 314 0.085 1274 118 0.093 0
SPTB_ENST00000389721 SPTB P11277 Spectrin beta chain, erythrocytic chr14 GO:0008092 Not Cancer Driver No 328 0.153 562 70 0.125 7
STAU2 STAU2 Q9NUL3 Double-stranded RNA-binding protein Staufen homolog 2 chr8 GO:0008092 Not Cancer Driver No 68 0.119 486 54 0.111 0
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 GO:0008092 Not Cancer Driver No 70 0.102 387 45 0.116 13
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0008092 Not Cancer Driver No 35 0.116 112 14 0.125 12
STX1A STX1A Q16623 Syntaxin-1A chr7 GO:0008092 Not Cancer Driver No 35 0.122 136 11 0.081 0
STXBP5 STXBP5 Q5T5C0 Syntaxin-binding protein 5 chr6 GO:0008092 Not Cancer Driver No 128 0.111 344 46 0.134 0
STXBP5L STXBP5L Q9Y2K9 Syntaxin-binding protein 5-like chr3 GO:0008092 Not Cancer Driver No 358 0.302 292 101 0.346 0
SYBU_ENST00000276646 SYBU Q9NX95 Syntabulin chr8 GO:0008092 Not Cancer Driver No 134 0.202 437 91 0.208 0
SYNM SYNM O15061 Synemin chr15 GO:0008092 Not Cancer Driver No 156 0.1 1244 131 0.105 0
SYNPO2_ENST00000429713 SYNPO2 Q9UMS6 Synaptopodin-2 chr4 GO:0008092 Not Cancer Driver No 240 0.22 978 219 0.224 0
SYT11 SYT11 Q9BT88 Synaptotagmin-11 chr1 GO:0008092 Not Cancer Driver No 64 0.148 105 23 0.219 0
TAOK1 TAOK1 Q7L7X3 Serine/threonine-protein kinase TAO1 chr17 GO:0008092 Not Cancer Driver No 116 0.116 601 59 0.098 0
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0008092 Not Cancer Driver No 191 0.155 666 102 0.153 0
TBCA_ENST00000380377 TBCA O75347 Tubulin-specific chaperone A chr5 GO:0008092 Not Cancer Driver No 8 0.074 30 1 0.033 0
TBCD TBCD Q9BTW9 Tubulin-specific chaperone D chr17 GO:0008092 Not Cancer Driver No 156 0.131 60 9 0.15 11
TBCEL_ENST00000529397 TBCEL Q5QJ74 Tubulin-specific chaperone cofactor E-like protein chr11 GO:0008092 Not Cancer Driver No 50 0.118 35 11 0.314 0
TBCE_ENST00000645351 TBCE Q15813 Tubulin-specific chaperone E chr1 GO:0008092 Not Cancer Driver No 70 0.133 87 7 0.08 1
TCAP TCAP O15273 Telethonin chr17 GO:0008092 Not Cancer Driver No 16 0.096 94 10 0.106 3
TLN1 TLN1 Q9Y490 Talin-1 chr9 GO:0008092 Not Cancer Driver No 278 0.109 1109 126 0.114 0
TMEM67 TMEM67 Q5HYA8 Meckelin chr8 GO:0008092 Not Cancer Driver No 120 0.121 11 0 0.0 37
TMOD1_ENST00000395211 TMOD1 P28289 Tropomodulin-1 chr9 GO:0008092 Not Cancer Driver No 41 0.114 195 29 0.149 0
TMOD2 TMOD2 Q9NZR1 Tropomodulin-2 chr15 GO:0008092 Not Cancer Driver No 33 0.094 216 22 0.102 0
TMOD3 TMOD3 Q9NYL9 Tropomodulin-3 chr15 GO:0008092 Not Cancer Driver No 40 0.114 190 24 0.126 0
TMOD4 TMOD4 Q9NZQ9 Tropomodulin-4 chr1 GO:0008092 Not Cancer Driver No 37 0.107 218 22 0.101 0
TNNC1 TNNC1 P63316 Troponin C, slow skeletal and cardiac muscles chr3 GO:0008092 Not Cancer Driver No 19 0.118 67 6 0.09 6
TNNI2_ENST00000381911 TNNI2 P48788 Troponin I, fast skeletal muscle chr11 GO:0008092 Not Cancer Driver No 45 0.247 171 44 0.257 1
TNNI3 TNNI3 P19429 Troponin I, cardiac muscle chr19 GO:0008092 Not Cancer Driver No 42 0.2 108 19 0.176 21
TNNI3K TNNI3K Q59H18 Serine/threonine-protein kinase TNNI3K chr1 GO:0008092 Not Cancer Driver No 234 0.28 78 26 0.333 1
TNNT1 TNNT1 P13805 Troponin T, slow skeletal muscle chr19 GO:0008092 Not Cancer Driver No 61 0.219 240 55 0.229 0
TNNT2 TNNT2 P45379 Troponin T, cardiac muscle chr1 GO:0008092 Not Cancer Driver No 59 0.198 272 53 0.195 21
TNNT3_ENST00000397301 TNNT3 P45378 Troponin T, fast skeletal muscle chr11 GO:0008092 Not Cancer Driver No 59 0.219 246 52 0.211 2
TOR1A TOR1A O14656 Torsin-1A chr9 GO:0008092 Not Cancer Driver No 33 0.099 0 0 0.0 3
TOR1AIP1_ENST00000606911 TOR1AIP1 Q5JTV8 Torsin-1A-interacting protein 1 chr1 GO:0008092 Not Cancer Driver No 71 0.122 401 44 0.11 0
TOR1B TOR1B O14657 Torsin-1B chr9 GO:0008092 Not Cancer Driver No 36 0.107 0 0 0.0 0
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 GO:0008092 Not Cancer Driver No 33 0.116 234 29 0.124 8
TRIM36 TRIM36 Q9NQ86 E3 ubiquitin-protein ligase TRIM36 chr5 GO:0008092 Not Cancer Driver No 106 0.146 89 21 0.236 1
TRIM63 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 GO:0008092 Not Cancer Driver No 47 0.133 71 13 0.183 0
TRIOBP_ENST00000644935 TRIOBP Q9H2D6 TRIO and F-actin-binding protein chr22 GO:0008092 Not Cancer Driver No 386 0.163 2196 370 0.168 1
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0008092 Not Cancer Driver No 255 0.262 148 32 0.216 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0008092 Not Cancer Driver No 142 0.163 231 34 0.147 44
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0008092 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TTBK2 TTBK2 Q6IQ55 Tau-tubulin kinase 2 chr15 GO:0008092 Not Cancer Driver No 151 0.121 848 107 0.126 0
TTLL7 TTLL7 Q6ZT98 Tubulin polyglutamylase TTLL7 chr1 GO:0008092 Not Cancer Driver No 169 0.191 330 68 0.206 0
TTN_ENST00000615779 TTN Q8WZ42 Titin chr2 GO:0008092 Not Cancer Driver No 7917 0.23 12926 2861 0.221 10
TUBGCP2_ENST00000368563 TUBGCP2 Q9BSJ2 Gamma-tubulin complex component 2 chr10 GO:0008092 Not Cancer Driver No 124 0.137 93 16 0.172 0
TUBGCP3 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 GO:0008092 Not Cancer Driver No 109 0.12 156 16 0.103 0
TUBGCP4 TUBGCP4 Q9UGJ1 Gamma-tubulin complex component 4 chr15 GO:0008092 Not Cancer Driver No 79 0.118 62 5 0.081 0
TUBGCP6 TUBGCP6 Q96RT7 Gamma-tubulin complex component 6 chr22 GO:0008092 Not Cancer Driver No 221 0.121 815 105 0.129 0
USH1C_ENST00000318024 USH1C Q9Y6N9 Harmonin chr11 GO:0008092 Not Cancer Driver No 118 0.214 153 45 0.294 0
USH1G USH1G Q495M9 Usher syndrome type-1G protein chr17 GO:0008092 Not Cancer Driver No 82 0.178 256 44 0.172 2
UTRN UTRN P46939 Utrophin chr6 GO:0008092 Not Cancer Driver No 476 0.139 1283 183 0.143 0
UXT_ENST00000333119 UXT Q9UBK9 Protein UXT chrX GO:0008092 Not Cancer Driver No 21 0.134 17 1 0.059 0
VAPB VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 GO:0008092 Not Cancer Driver No 16 0.066 138 8 0.058 3
WASHC1 WASHC1 A8K0Z3 WASH complex subunit 1 chr9 GO:0008092 Not Cancer Driver No 6 0.013 336 6 0.018 0
XIRP2_ENST00000628543 XIRP2 A4UGR9 Xin actin-binding repeat-containing protein 2 chr2 GO:0008092 Not Cancer Driver No 1094 0.324 2456 784 0.319 0