Total number of protein in "GO:0007249" GO term: 48
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0007249 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| AVPR2_ENST00000337474 | AVPR2 | P30518 | Vasopressin V2 receptor | chrX | GO:0007249 | Not Cancer Driver | No | 58 | 0.156 | 56 | 7 | 0.125 | 84 |
| AZI2 | AZI2 | Q9H6S1 | 5-azacytidine-induced protein 2 | chr3 | GO:0007249 | Not Cancer Driver | No | 31 | 0.079 | 192 | 13 | 0.068 | 0 |
| BCL10 | BCL10 | O95999 | B-cell lymphoma/leukemia 10 | chr1 | GO:0007249 | Census, Compendium | Yes | 36 | 0.155 | 151 | 25 | 0.166 | 0 |
| BCL3 | BCL3 | P20749 | B-cell lymphoma 3 protein | chr19 | GO:0007249 | Census | Yes | 44 | 0.097 | 259 | 23 | 0.089 | 0 |
| BIRC2 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | GO:0007249 | Not Cancer Driver | No | 69 | 0.112 | 83 | 9 | 0.108 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | GO:0007249 | Census, Compendium | Yes | 77 | 0.127 | 98 | 16 | 0.163 | 0 |
| BTK_ENST00000308731 | BTK | Q06187 | Tyrosine-protein kinase BTK | chrX | GO:0007249 | Census, Compendium | Yes | 147 | 0.223 | 114 | 27 | 0.237 | 110 |
| CARD11 | CARD11 | Q9BXL7 | Caspase recruitment domain-containing protein 11 | chr7 | GO:0007249 | Census, Compendium | Yes | 303 | 0.263 | 530 | 140 | 0.264 | 5 |
| CARD9 | CARD9 | Q9H257 | Caspase recruitment domain-containing protein 9 | chr9 | GO:0007249 | Not Cancer Driver | No | 72 | 0.134 | 225 | 35 | 0.156 | 11 |
| CHUK | CHUK | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | chr10 | GO:0007249 | Not Cancer Driver | No | 74 | 0.099 | 116 | 9 | 0.078 | 0 |
| DEFB124 | DEFB124 | Q8NES8 | Beta-defensin 124 | chr20 | GO:0007249 | Not Cancer Driver | No | 9 | 0.127 | 3 | 0 | 0.0 | 0 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0007249 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EDNRA | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0007249 | Not Cancer Driver | No | 62 | 0.145 | 21 | 6 | 0.286 | 2 |
| EDNRB_ENST00000334286 | EDNRB | P24530 | Endothelin receptor type B | chr13 | GO:0007249 | Not Cancer Driver | No | 112 | 0.253 | 56 | 19 | 0.339 | 6 |
| FAIM_ENST00000393035 | FAIM | Q9NVQ4 | Fas apoptotic inhibitory molecule 1 | chr3 | GO:0007249 | Not Cancer Driver | No | 20 | 0.112 | 1 | 0 | 0.0 | 0 |
| HACD3 | HACD3 | Q9P035 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 | chr15 | GO:0007249 | Not Cancer Driver | No | 28 | 0.077 | 10 | 0 | 0.0 | 0 |
| IKBKB | IKBKB | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | chr8 | GO:0007249 | Census, Compendium | Yes | 106 | 0.14 | 211 | 31 | 0.147 | 1 |
| IKBKG_ENST00000611071 | IKBKG | Q9Y6K9 | NF-kappa-B essential modulator | chrX | GO:0007249 | Not Cancer Driver | No | 6 | 0.014 | 301 | 6 | 0.02 | 22 |
| IRAK1BP1 | IRAK1BP1 | Q5VVH5 | Interleukin-1 receptor-associated kinase 1-binding protein 1 | chr6 | GO:0007249 | Not Cancer Driver | No | 40 | 0.154 | 107 | 15 | 0.14 | 0 |
| IRAK2 | IRAK2 | O43187 | Interleukin-1 receptor-associated kinase-like 2 | chr3 | GO:0007249 | Not Cancer Driver | No | 84 | 0.134 | 202 | 32 | 0.158 | 0 |
| MAP3K14 | MAP3K14 | Q99558 | Mitogen-activated protein kinase kinase kinase 14 | chr17 | GO:0007249 | Not Cancer Driver | No | 94 | 0.099 | 543 | 52 | 0.096 | 0 |
| MAP3K7 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | GO:0007249 | Not Cancer Driver | No | 104 | 0.172 | 333 | 66 | 0.198 | 6 |
| NFKBIA | NFKBIA | P25963 | NF-kappa-B inhibitor alpha | chr14 | GO:0007249 | Compendium | Yes | 37 | 0.117 | 102 | 9 | 0.088 | 1 |
| NFKBIL1 | NFKBIL1 | Q9UBC1 | NF-kappa-B inhibitor-like protein 1 | chr6 | GO:0007249 | Not Cancer Driver | No | 37 | 0.097 | 316 | 33 | 0.104 | 0 |
| NKIRAS1 | NKIRAS1 | Q9NYS0 | NF-kappa-B inhibitor-interacting Ras-like protein 1 | chr3 | GO:0007249 | Not Cancer Driver | No | 20 | 0.104 | 21 | 1 | 0.048 | 0 |
| NKIRAS2_ENST00000393880 | NKIRAS2 | Q9NYR9 | NF-kappa-B inhibitor-interacting Ras-like protein 2 | chr17 | GO:0007249 | Not Cancer Driver | No | 23 | 0.12 | 27 | 3 | 0.111 | 0 |
| NLRC3 | NLRC3 | Q7RTR2 | NLR family CARD domain-containing protein 3 | chr16 | GO:0007249 | Not Cancer Driver | No | 176 | 0.165 | 147 | 33 | 0.224 | 0 |
| REL | REL | Q04864 | Proto-oncogene c-Rel | chr2 | GO:0007249 | Census | Yes | 68 | 0.11 | 363 | 43 | 0.118 | 0 |
| RELA | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0007249 | Compendium | Yes | 75 | 0.136 | 400 | 48 | 0.12 | 0 |
| RELB | RELB | Q01201 | Transcription factor RelB | chr19 | GO:0007249 | Not Cancer Driver | No | 65 | 0.112 | 348 | 39 | 0.112 | 0 |
| RIPK2 | RIPK2 | O43353 | Receptor-interacting serine/threonine-protein kinase 2 | chr8 | GO:0007249 | Not Cancer Driver | No | 63 | 0.117 | 143 | 20 | 0.14 | 0 |
| RIPK3 | RIPK3 | Q9Y572 | Receptor-interacting serine/threonine-protein kinase 3 | chr14 | GO:0007249 | Not Cancer Driver | No | 66 | 0.127 | 295 | 39 | 0.132 | 0 |
| ROCK1 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0007249 | Not Cancer Driver | No | 184 | 0.136 | 780 | 103 | 0.132 | 0 |
| ROCK2 | ROCK2 | O75116 | Rho-associated protein kinase 2 | chr2 | GO:0007249 | Not Cancer Driver | No | 145 | 0.104 | 732 | 81 | 0.111 | 0 |
| SNIP1 | SNIP1 | Q8TAD8 | Smad nuclear-interacting protein 1 | chr1 | GO:0007249 | Not Cancer Driver | No | 58 | 0.146 | 285 | 40 | 0.14 | 1 |
| TANK | TANK | Q92844 | TRAF family member-associated NF-kappa-B activator | chr2 | GO:0007249 | Not Cancer Driver | No | 42 | 0.099 | 302 | 26 | 0.086 | 0 |
| TBK1 | TBK1 | Q9UHD2 | Serine/threonine-protein kinase TBK1 | chr12 | GO:0007249 | Not Cancer Driver | No | 101 | 0.139 | 42 | 5 | 0.119 | 12 |
| TBKBP1 | TBKBP1 | A7MCY6 | TANK-binding kinase 1-binding protein 1 | chr17 | GO:0007249 | Not Cancer Driver | No | 52 | 0.085 | 404 | 31 | 0.077 | 0 |
| TIAF1 | MYO18A | O95411 | Putative TGFB1-induced anti-apoptotic factor 1 | chr17 | GO:0007249 | Not Cancer Driver | No | 16 | 0.139 | 30 | 5 | 0.167 | 0 |
| TIFAB | TIFAB | Q6ZNK6 | TRAF-interacting protein with FHA domain-containing protein B | chr5 | GO:0007249 | Not Cancer Driver | No | 32 | 0.199 | 26 | 7 | 0.269 | 0 |
| TIFA_ENST00000500655 | TIFA | Q96CG3 | TRAF-interacting protein with FHA domain-containing protein A | chr4 | GO:0007249 | Not Cancer Driver | No | 17 | 0.092 | 32 | 5 | 0.156 | 0 |
| TIRAP_ENST00000392680 | TIRAP | P58753 | Toll/interleukin-1 receptor domain-containing adapter protein | chr11 | GO:0007249 | Not Cancer Driver | No | 28 | 0.127 | 80 | 6 | 0.075 | 0 |
| TLR7 | TLR7 | Q9NYK1 | Toll-like receptor 7 | chrX | GO:0007249 | Not Cancer Driver | No | 182 | 0.173 | 14 | 1 | 0.071 | 1 |
| TLR8_ENST00000218032 | TLR8 | Q9NR97 | Toll-like receptor 8 | chrX | GO:0007249 | Not Cancer Driver | No | 180 | 0.173 | 30 | 7 | 0.233 | 0 |
| TLR9 | TLR9 | Q9NR96 | Toll-like receptor 9 | chr3 | GO:0007249 | Not Cancer Driver | No | 141 | 0.137 | 35 | 3 | 0.086 | 0 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0007249 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
| ZNF675 | ZNF675 | Q8TD23 | Zinc finger protein 675 | chr19 | GO:0007249 | Not Cancer Driver | No | 114 | 0.201 | 91 | 19 | 0.209 | 0 |