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Total number of protein in "GO:0006952" GO term:  403

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A2M A2M P01023 Alpha-2-macroglobulin chr12 GO:0006952 Not Cancer Driver No 260 0.176 144 22 0.153 0
ABI3 ABI3 Q9P2A4 ABI gene family member 3 chr17 GO:0006952 Not Cancer Driver No 46 0.126 248 31 0.125 0
ACKR1_ENST00000368122 ACKR1 Q16570 Atypical chemokine receptor 1 chr1 GO:0006952 Not Cancer Driver No 94 0.28 0 0 0.0 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0006952 Not Cancer Driver No 5 0.01 36 0 0.0 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0006952 Census, Compendium Yes 78 0.153 21 8 0.381 8
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0006952 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0006952 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0006952 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0006952 Not Cancer Driver No 23 0.069 0 0 0.0 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0006952 Not Cancer Driver No 67 0.144 161 10 0.062 0
AHSG AHSG P02765 Alpha-2-HS-glycoprotein chr3 GO:0006952 Not Cancer Driver No 74 0.202 131 41 0.313 0
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 GO:0006952 Not Cancer Driver No 107 0.118 537 67 0.125 0
ALS2 ALS2 Q96Q42 Alsin chr2 GO:0006952 Not Cancer Driver No 194 0.117 353 36 0.102 0
APCS APCS P02743 Serum amyloid P-component chr1 GO:0006952 Not Cancer Driver No 73 0.327 0 0 0.0 0
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0006952 Not Cancer Driver No 13 0.13 0 0 0.0 0
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0006952 Not Cancer Driver No 77 0.194 298 65 0.218 0
APOBEC3A_ENST00000249116 APOBEC3A P31941 DNA dC->dU-editing enzyme APOBEC-3A chr22 GO:0006952 Not Cancer Driver No 27 0.136 8 1 0.125 0
APOL1_ENST00000397279 APOL1 O14791 Apolipoprotein L1 chr22 GO:0006952 Not Cancer Driver No 51 0.128 82 9 0.11 2
APOL2 APOL2 Q9BQE5 Apolipoprotein L2 chr22 GO:0006952 Not Cancer Driver No 34 0.101 94 8 0.085 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0006952 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARL8B ARL8B Q9NVJ2 ADP-ribosylation factor-like protein 8B chr3 GO:0006952 Not Cancer Driver No 28 0.151 0 0 0.0 0
ASIC1_ENST00000447966 ASIC1 P78348 Acid-sensing ion channel 1 chr12 GO:0006952 Not Cancer Driver No 69 0.131 17 2 0.118 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0006952 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATAD3A ATAD3A Q9NVI7 ATPase family AAA domain-containing protein 3A chr1 GO:0006952 Not Cancer Driver No 66 0.104 269 24 0.089 2
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0006952 Not Cancer Driver No 230 0.225 161 34 0.211 8
AZU1 AZU1 P20160 Azurocidin chr19 GO:0006952 Not Cancer Driver No 42 0.167 53 13 0.245 0
B4GALT1 B4GALT1 P15291 Beta-1,4-galactosyltransferase 1 chr9 GO:0006952 Not Cancer Driver No 38 0.095 129 13 0.101 0
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 GO:0006952 Not Cancer Driver No 28 0.224 119 25 0.21 0
BATF2 BATF2 Q8N1L9 Basic leucine zipper transcriptional factor ATF-like 2 chr11 GO:0006952 Not Cancer Driver No 28 0.102 202 19 0.094 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0006952 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0006952 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0006952 Census Yes 44 0.097 259 23 0.089 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0006952 Not Cancer Driver No 45 0.1 190 19 0.1 0
BPIFB1 BPIFB1 Q8TDL5 BPI fold-containing family B member 1 chr20 GO:0006952 Not Cancer Driver No 93 0.192 7 0 0.0 0
BRINP1 BRINP1 O60477 BMP/retinoic acid-inducible neural-specific protein 1 chr9 GO:0006952 Not Cancer Driver No 273 0.359 36 17 0.472 0
C3 C3 P01024 Complement C3 chr19 GO:0006952 Not Cancer Driver No 337 0.203 287 50 0.174 12
C5 C5 P01031 Complement C5 chr9 GO:0006952 Not Cancer Driver No 192 0.115 84 9 0.107 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0006952 Not Cancer Driver No 71 0.203 0 0 0.0 0
C7 C7 P10643 Complement component C7 chr5 GO:0006952 Not Cancer Driver No 291 0.345 89 37 0.416 5
C8A C8A P07357 Complement component C8 alpha chain chr1 GO:0006952 Not Cancer Driver No 176 0.301 25 9 0.36 0
C8B C8B P07358 Complement component C8 beta chain chr1 GO:0006952 Not Cancer Driver No 186 0.315 29 11 0.379 0
C8G C8G P07360 Complement component C8 gamma chain chr9 GO:0006952 Not Cancer Driver No 10 0.05 26 2 0.077 0
C9 C9 P02748 Complement component C9 chr5 GO:0006952 Not Cancer Driver No 156 0.279 40 8 0.2 2
CAMLG CAMLG P49069 Guided entry of tail-anchored proteins factor CAMLG chr5 GO:0006952 Not Cancer Driver No 32 0.108 157 16 0.102 0
CAMP CAMP P49913 Cathelicidin antimicrobial peptide chr3 GO:0006952 Not Cancer Driver No 25 0.147 48 4 0.083 0
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0006952 Not Cancer Driver No 53 0.099 126 7 0.056 1
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 GO:0006952 Not Cancer Driver No 72 0.134 225 35 0.156 11
CCDC88B CCDC88B A6NC98 Coiled-coil domain-containing protein 88B chr11 GO:0006952 Not Cancer Driver No 156 0.106 1152 130 0.113 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0006952 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR3_ENST00000357422 CCR3 P51677 C-C chemokine receptor type 3 chr3 GO:0006952 Not Cancer Driver No 84 0.237 0 0 0.0 0
CCR5 CCR5 P51681 C-C chemokine receptor type 5 chr3 GO:0006952 Not Cancer Driver No 107 0.304 0 0 0.0 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0006952 Not Cancer Driver No 56 0.15 13 2 0.154 0
CCR9 CCR9 P51686 C-C chemokine receptor type 9 chr3 GO:0006952 Not Cancer Driver No 60 0.163 0 0 0.0 0
CD163 CD163 Q86VB7 Scavenger receptor cysteine-rich type 1 protein M130 chr12 GO:0006952 Not Cancer Driver No 359 0.311 68 27 0.397 0
CD300C CD300C Q08708 CMRF35-like molecule 6 chr17 GO:0006952 Not Cancer Driver No 67 0.299 85 24 0.282 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0006952 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD48_ENST00000368046 CD48 P09326 CD48 antigen chr1 GO:0006952 Not Cancer Driver No 39 0.16 2 0 0.0 0
CD5L CD5L O43866 CD5 antigen-like chr1 GO:0006952 Not Cancer Driver No 145 0.418 33 13 0.394 0
CD6 CD6 P30203 T-cell differentiation antigen CD6 chr11 GO:0006952 Not Cancer Driver No 91 0.136 268 41 0.153 0
CD68 CD68 P34810 Macrosialin chr17 GO:0006952 Not Cancer Driver No 26 0.073 192 13 0.068 0
CD83 CD83 Q01151 CD83 antigen chr6 GO:0006952 Not Cancer Driver No 24 0.117 48 8 0.167 0
CD84 CD84 Q9UIB8 SLAM family member 5 chr1 GO:0006952 Not Cancer Driver No 82 0.238 52 11 0.212 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0006952 Not Cancer Driver No 3 0.009 276 2 0.007 0
CEBPE CEBPE Q15744 CCAAT/enhancer-binding protein epsilon chr14 GO:0006952 Not Cancer Driver No 56 0.199 257 53 0.206 0
CEBPG_ENST00000585933 CEBPG P53567 CCAAT/enhancer-binding protein gamma chr19 GO:0006952 Not Cancer Driver No 13 0.087 141 12 0.085 0
CFB CFB P00751 Complement factor B chr6 GO:0006952 Not Cancer Driver No 75 0.098 112 20 0.179 7
CFD_ENST00000327726 CFD P00746 Complement factor D chr19 GO:0006952 Not Cancer Driver No 6 0.024 69 3 0.043 2
CFH CFH P08603 Complement factor H chr1 GO:0006952 Not Cancer Driver No 355 0.288 89 28 0.315 42
CFHR1 CFHR1 Q03591 Complement factor H-related protein 1 chr1 GO:0006952 Not Cancer Driver No 68 0.206 42 11 0.262 0
CFHR2 CFHR2 P36980 Complement factor H-related protein 2 chr1 GO:0006952 Not Cancer Driver No 97 0.359 14 8 0.571 0
CFHR5 CFHR5 Q9BXR6 Complement factor H-related protein 5 chr1 GO:0006952 Not Cancer Driver No 162 0.285 40 9 0.225 0
CFP CFP P27918 Properdin chrX GO:0006952 Not Cancer Driver No 60 0.128 48 7 0.146 6
CHMP3 CHMP3 Q9Y3E7 Charged multivesicular body protein 3 chr2 GO:0006952 Not Cancer Driver No 25 0.113 137 13 0.095 0
CLEC1A CLEC1A Q8NC01 C-type lectin domain family 1 member A chr12 GO:0006952 Not Cancer Driver No 62 0.221 76 19 0.25 0
CLEC1B CLEC1B Q9P126 C-type lectin domain family 1 member B chr12 GO:0006952 Not Cancer Driver No 50 0.218 3 0 0.0 0
CLEC2A CLEC2A Q6UVW9 C-type lectin domain family 2 member A chr12 GO:0006952 Not Cancer Driver No 10 0.057 0 0 0.0 0
CLEC4A CLEC4A Q9UMR7 C-type lectin domain family 4 member A chr12 GO:0006952 Not Cancer Driver No 35 0.148 22 4 0.182 0
CLEC4C_ENST00000360345 CLEC4C Q8WTT0 C-type lectin domain family 4 member C chr12 GO:0006952 Not Cancer Driver No 58 0.272 5 1 0.2 0
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 GO:0006952 Not Cancer Driver No 59 0.274 17 3 0.176 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 GO:0006952 Not Cancer Driver No 56 0.256 5 2 0.4 0
CLEC5A CLEC5A Q9NY25 C-type lectin domain family 5 member A chr7 GO:0006952 Not Cancer Driver No 46 0.245 0 0 0.0 0
CLEC6A CLEC6A Q6EIG7 C-type lectin domain family 6 member A chr12 GO:0006952 Not Cancer Driver No 41 0.196 7 0 0.0 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0006952 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLPB CLPB Q9H078 Caseinolytic peptidase B protein homolog chr11 GO:0006952 Not Cancer Driver No 69 0.098 224 25 0.112 11
COLEC10 COLEC10 Q9Y6Z7 Collectin-10 chr8 GO:0006952 Not Cancer Driver No 58 0.209 95 23 0.242 1
COLEC11_ENST00000349077 COLEC11 Q9BWP8 Collectin-11 chr2 GO:0006952 Not Cancer Driver No 72 0.266 158 40 0.253 2
COLEC12 COLEC12 Q5KU26 Collectin-12 chr18 GO:0006952 Not Cancer Driver No 147 0.198 450 90 0.2 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0006952 Compendium Yes 383 0.188 151 42 0.278 0
CR2_ENST00000367058 CR2 P20023 Complement receptor type 2 chr1 GO:0006952 Not Cancer Driver No 273 0.264 85 28 0.329 0
CRP CRP P02741 C-reactive protein chr1 GO:0006952 Not Cancer Driver No 59 0.263 0 0 0.0 0
CSF3R_ENST00000361632 CSF3R Q99062 Granulocyte colony-stimulating factor receptor chr1 GO:0006952 Census, Compendium Yes 131 0.157 209 34 0.163 2
CST3_ENST00000376925 CST3 P01034 Cystatin-C chr20 GO:0006952 Not Cancer Driver No 17 0.116 31 1 0.032 2
CTSG CTSG P08311 Cathepsin G chr14 GO:0006952 Not Cancer Driver No 65 0.255 80 29 0.362 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0006952 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0006952 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0006952 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0006952 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0006952 Not Cancer Driver No 11 0.101 0 0 0.0 0
CXCL9 CXCL9 Q07325 C-X-C motif chemokine 9 chr4 GO:0006952 Not Cancer Driver No 32 0.256 38 16 0.421 0
CXCR2 CXCR2 P25025 C-X-C chemokine receptor type 2 chr2 GO:0006952 Not Cancer Driver No 87 0.242 8 0 0.0 0
CYBB CYBB P04839 Cytochrome b-245 heavy chain chrX GO:0006952 Not Cancer Driver No 109 0.191 11 3 0.273 65
CYSLTR1 CYSLTR1 Q9Y271 Cysteinyl leukotriene receptor 1 chrX GO:0006952 Not Cancer Driver No 58 0.172 8 1 0.125 0
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:0006952 Not Cancer Driver No 193 0.135 114 11 0.096 0
DCDC2 DCDC2 Q9UHG0 Doublecortin domain-containing protein 2 chr6 GO:0006952 Not Cancer Driver No 72 0.151 264 41 0.155 2
DCD_ENST00000293371 DCD P81605 Dermcidin chr12 GO:0006952 Not Cancer Driver No 25 0.227 67 19 0.284 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0006952 Not Cancer Driver No 118 0.128 61 10 0.164 2
DEFA3 DEFA3 P59666 Neutrophil defensin 3 chr8 GO:0006952 Not Cancer Driver No 15 0.16 0 0 0.0 0
DEFA4 DEFA4 P12838 Defensin alpha 4 chr8 GO:0006952 Not Cancer Driver No 35 0.361 17 5 0.294 0
DEFA5 DEFA5 Q01523 Defensin-5 chr8 GO:0006952 Not Cancer Driver No 16 0.17 17 3 0.176 0
DEFA6 DEFA6 Q01524 Defensin-6 chr8 GO:0006952 Not Cancer Driver No 19 0.19 15 2 0.133 0
DEFB1 DEFB1 P60022 Beta-defensin 1 chr8 GO:0006952 Not Cancer Driver No 8 0.118 0 0 0.0 0
DEFB106B DEFB106B Q8N104 Beta-defensin 106 chr8 GO:0006952 Not Cancer Driver No 15 0.231 0 0 0.0 0
DEFB114 DEFB114 Q30KQ6 Beta-defensin 114 chr6 GO:0006952 Not Cancer Driver No 31 0.449 0 0 0.0 0
DEFB119_ENST00000376321 DEFB119 Q8N690 Beta-defensin 119 chr20 GO:0006952 Not Cancer Driver No 25 0.298 0 0 0.0 0
DLEC1 DLEC1 Q9Y238 Deleted in lung and esophageal cancer protein 1 chr3 GO:0006952 Not Cancer Driver No 220 0.125 416 66 0.159 0
DMBT1_ENST00000619379 DMBT1 Q9UGM3 Deleted in malignant brain tumors 1 protein chr10 GO:0006952 Not Cancer Driver No 506 0.21 404 64 0.158 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0006952 Not Cancer Driver No 151 0.197 8 1 0.125 0
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0006952 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD4 DRD4 P21917 D(4) dopamine receptor chr11 GO:0006952 Not Cancer Driver No 26 0.062 109 0 0.0 0
DUOX1 DUOX1 Q9NRD9 Dual oxidase 1 chr15 GO:0006952 Not Cancer Driver No 193 0.124 158 17 0.108 0
DUOX2 DUOX2 Q9NRD8 Dual oxidase 2 chr15 GO:0006952 Not Cancer Driver No 245 0.158 182 25 0.137 3
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:0006952 Not Cancer Driver No 87 0.138 238 29 0.122 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:0006952 Not Cancer Driver No 26 0.12 54 6 0.111 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0006952 Not Cancer Driver No 229 0.143 1079 153 0.142 2
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0006952 Not Cancer Driver No 39 0.146 18 3 0.167 89
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0006952 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPO EPO P01588 Erythropoietin chr7 GO:0006952 Not Cancer Driver No 27 0.14 9 1 0.111 1
EPX EPX P11678 Eosinophil peroxidase chr17 GO:0006952 Not Cancer Driver No 144 0.201 55 6 0.109 1
EXT1 EXT1 Q16394 Exostosin-1 chr8 GO:0006952 Census Yes 107 0.143 58 7 0.121 12
F12 F12 P00748 Coagulation factor XII chr5 GO:0006952 Not Cancer Driver No 53 0.086 104 9 0.087 13
F2 F2 P00734 Prothrombin chr11 GO:0006952 Not Cancer Driver No 115 0.185 97 25 0.258 10
F8 F8 P00451 Coagulation factor VIII chrX GO:0006952 Not Cancer Driver No 414 0.176 931 174 0.187 472
FAM3A_ENST00000447601 FAM3A P98173 Protein FAM3A chrX GO:0006952 Not Cancer Driver No 27 0.117 48 9 0.188 0
FBXL20 FBXL20 Q96IG2 F-box/LRR-repeat protein 20 chr17 GO:0006952 Not Cancer Driver No 48 0.11 1 0 0.0 0
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 GO:0006952 Not Cancer Driver No 62 0.166 37 5 0.135 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0006952 Census Yes 51 0.165 99 30 0.303 0
FCGR3A_ENST00000443193 FCGR3A P08637 Low affinity immunoglobulin gamma Fc region receptor III-A chr1 GO:0006952 Not Cancer Driver No 69 0.272 0 0 0.0 1
FCMR FCMR O60667 Fas apoptotic inhibitory molecule 3 chr1 GO:0006952 Not Cancer Driver No 55 0.141 229 29 0.127 0
FCN1 FCN1 O00602 Ficolin-1 chr9 GO:0006952 Not Cancer Driver No 107 0.328 88 15 0.17 0
FCN2 FCN2 Q15485 Ficolin-2 chr9 GO:0006952 Not Cancer Driver No 73 0.233 80 19 0.237 0
FCN3 FCN3 O75636 Ficolin-3 chr1 GO:0006952 Not Cancer Driver No 46 0.154 65 19 0.292 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0006952 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0006952 Not Cancer Driver No 89 0.181 143 29 0.203 7
FN1 FN1 P02751 Fibronectin chr2 GO:0006952 Compendium Yes 394 0.159 1243 185 0.149 8
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0006952 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOXN1 FOXN1 O15353 Forkhead box protein N1 chr17 GO:0006952 Not Cancer Driver No 90 0.139 483 65 0.135 2
GABRA5_ENST00000355395 GABRA5 P31644 Gamma-aminobutyric acid receptor subunit alpha-5 chr15 GO:0006952 Not Cancer Driver No 146 0.316 55 14 0.255 3
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 GO:0006952 Not Cancer Driver No 39 0.116 24 3 0.125 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0006952 Census, Compendium Yes 111 0.251 364 87 0.239 2
GBP2 GBP2 P32456 Guanylate-binding protein 2 chr1 GO:0006952 Not Cancer Driver No 75 0.127 134 15 0.112 0
GBP4 GBP4 Q96PP9 Guanylate-binding protein 4 chr1 GO:0006952 Not Cancer Driver No 114 0.178 165 31 0.188 0
GBP6 GBP6 Q6ZN66 Guanylate-binding protein 6 chr1 GO:0006952 Not Cancer Driver No 112 0.177 157 21 0.134 0
GBP7 GBP7 Q8N8V2 Guanylate-binding protein 7 chr1 GO:0006952 Not Cancer Driver No 88 0.138 93 8 0.086 0
GNLY_ENST00000263863 GNLY P22749 Granulysin chr2 GO:0006952 Not Cancer Driver No 28 0.193 19 1 0.053 0
GRIK2 GRIK2 Q13002 Glutamate receptor ionotropic, kainate 2 chr6 GO:0006952 Not Cancer Driver No 284 0.313 57 19 0.333 0
GRM7 GRM7 Q14831 Metabotropic glutamate receptor 7 chr3 GO:0006952 Not Cancer Driver No 316 0.345 91 31 0.341 1
GZMB GZMB P10144 Granzyme B chr14 GO:0006952 Not Cancer Driver No 49 0.198 103 23 0.223 0
H2BFS H2BC12L P57053 Histone H2B type F-S chr21 GO:0006952 Not Cancer Driver No 1 0.008 86 1 0.012 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0006952 Not Cancer Driver No 7 0.083 4 0 0.0 4
HIST1H2BC H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0006952 Not Cancer Driver No 53 0.421 79 27 0.342 0
HIST1H2BE H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0006952 Not Cancer Driver No 26 0.206 79 16 0.203 0
HIST1H2BF H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0006952 Not Cancer Driver No 30 0.238 79 20 0.253 0
HIST1H2BG H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0006952 Not Cancer Driver No 45 0.357 79 25 0.316 0
HIST1H2BI H2BC10 P62807 Histone H2B type 1-C/E/F/G/I chr6 GO:0006952 Not Cancer Driver No 30 0.238 79 18 0.228 0
HIST1H2BJ_ENST00000339812 H2BC11 P06899 Histone H2B type 1-J chr6 GO:0006952 Not Cancer Driver No 22 0.175 75 13 0.173 0
HIST1H2BK H2BC12 O60814 Histone H2B type 1-K chr6 GO:0006952 Not Cancer Driver No 42 0.333 78 29 0.372 0
HIST2H2BE H2BC21 Q16778 Histone H2B type 2-E chr1 GO:0006952 Not Cancer Driver No 47 0.373 77 30 0.39 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:0006952 Compendium Yes 78 0.215 169 34 0.201 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0006952 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0006952 Not Cancer Driver No 94 0.278 85 22 0.259 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0006952 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0006952 Not Cancer Driver No 38 0.182 207 38 0.184 0
HP HP P00738 Haptoglobin chr16 GO:0006952 Not Cancer Driver No 39 0.096 57 2 0.035 1
HPR HPR P00739 Haptoglobin-related protein chr16 GO:0006952 Not Cancer Driver No 58 0.167 22 4 0.182 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0006952 Census, Compendium Yes 107 0.566 16 4 0.25 18
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0006952 Not Cancer Driver No 121 0.23 277 75 0.271 2
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0006952 Not Cancer Driver No 59 0.112 335 37 0.11 0
HTR1A HTR1A P08908 5-hydroxytryptamine receptor 1A chr5 GO:0006952 Not Cancer Driver No 170 0.403 100 49 0.49 0
HTR2C HTR2C P28335 5-hydroxytryptamine receptor 2C chrX GO:0006952 Not Cancer Driver No 140 0.306 40 11 0.275 0
ICOSLG_ENST00000407780 ICOSLG O75144 ICOS ligand chr21 GO:0006952 Not Cancer Driver No 25 0.083 30 2 0.067 0
IFIT1 IFIT1 P09914 Interferon-induced protein with tetratricopeptide repeats 1 chr10 GO:0006952 Not Cancer Driver No 49 0.103 52 3 0.058 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0006952 Not Cancer Driver No 51 0.307 23 6 0.261 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0006952 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0006952 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL17RB IL17RB Q9NRM6 Interleukin-17 receptor B chr3 GO:0006952 Not Cancer Driver No 50 0.1 30 3 0.1 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0006952 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0006952 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0006952 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1F10_ENST00000341010 IL1F10 Q8WWZ1 Interleukin-1 family member 10 chr2 GO:0006952 Not Cancer Driver No 30 0.197 10 1 0.1 0
IL1RL2 IL1RL2 Q9HB29 Interleukin-1 receptor-like 2 chr2 GO:0006952 Not Cancer Driver No 114 0.198 11 4 0.364 0
IL1RN_ENST00000409930 IL1RN P18510 Interleukin-1 receptor antagonist protein chr2 GO:0006952 Not Cancer Driver No 34 0.192 17 7 0.412 0
IL20RB IL20RB Q6UXL0 Interleukin-20 receptor subunit beta chr3 GO:0006952 Not Cancer Driver No 40 0.129 0 0 0.0 0
IL22_ENST00000328087 IL22 Q9GZX6 Interleukin-22 chr12 GO:0006952 Not Cancer Driver No 32 0.179 0 0 0.0 0
IL25 IL25 Q9H293 Interleukin-25 chr14 GO:0006952 Not Cancer Driver No 30 0.169 50 8 0.16 0
IL2RA IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 GO:0006952 Not Cancer Driver No 51 0.188 131 29 0.221 2
IL31RA_ENST00000297015 IL31RA Q8NI17 Interleukin-31 receptor subunit alpha chr5 GO:0006952 Not Cancer Driver No 117 0.16 163 30 0.184 1
IL32 IL32 P24001 Interleukin-32 chr16 GO:0006952 Not Cancer Driver No 41 0.175 70 17 0.243 0
IL36A IL36A Q9UHA7 Interleukin-36 alpha chr2 GO:0006952 Not Cancer Driver No 44 0.278 13 3 0.231 0
IL36B IL36B Q9NZH7 Interleukin-36 beta chr2 GO:0006952 Not Cancer Driver No 53 0.323 32 8 0.25 0
IL36G IL36G Q9NZH8 Interleukin-36 gamma chr2 GO:0006952 Not Cancer Driver No 35 0.207 23 5 0.217 0
IL36RN_ENST00000346807 IL36RN Q9UBH0 Interleukin-36 receptor antagonist protein chr2 GO:0006952 Not Cancer Driver No 34 0.219 7 4 0.571 4
IL37 IL37 Q9NZH6 Interleukin-37 chr2 GO:0006952 Not Cancer Driver No 56 0.257 71 13 0.183 1
IL4 IL4 P05112 Interleukin-4 chr5 GO:0006952 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0006952 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL5RA_ENST00000256452 IL5RA Q01344 Interleukin-5 receptor subunit alpha chr3 GO:0006952 Not Cancer Driver No 92 0.219 23 5 0.217 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0006952 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0006952 Not Cancer Driver No 55 0.118 165 23 0.139 1
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0006952 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0006952 Not Cancer Driver No 61 0.15 98 5 0.051 0
INS INS P01308 Insulin chr11 GO:0006952 Not Cancer Driver No 15 0.136 5 1 0.2 22
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:0006952 Census, Compendium Yes 99 0.22 155 45 0.29 0
IRF8 IRF8 Q02556 Interferon regulatory factor 8 chr16 GO:0006952 Not Cancer Driver No 80 0.188 77 20 0.26 2
IRGC IRGC Q6NXR0 Interferon-inducible GTPase 5 chr19 GO:0006952 Not Cancer Driver No 98 0.212 158 36 0.228 0
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0006952 Not Cancer Driver No 9 0.05 45 1 0.022 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0006952 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITIH4 ITIH4 Q14624 Inter-alpha-trypsin inhibitor heavy chain H4 chr3 GO:0006952 Not Cancer Driver No 103 0.111 264 39 0.148 0
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 GO:0006952 Census Yes 139 0.224 43 10 0.233 1
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0006952 Census, Compendium Yes 136 0.12 59 5 0.085 5
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 GO:0006952 Not Cancer Driver No 60 0.141 31 6 0.194 3
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 GO:0006952 Census, Compendium Yes 122 0.127 586 67 0.114 0
KIR3DL1 KIR3DL1 P43629 Killer cell immunoglobulin-like receptor 3DL1 chr19 GO:0006952 Not Cancer Driver No 124 0.279 184 48 0.261 0
KIR3DL2 KIR3DL2 P43630 Killer cell immunoglobulin-like receptor 3DL2 chr19 GO:0006952 Not Cancer Driver No 91 0.2 118 31 0.263 0
KL KL Q9UEF7 Klotho chr13 GO:0006952 Not Cancer Driver No 175 0.173 104 5 0.048 1
KLRC2 KLRC2 P26717 NKG2-C type II integral membrane protein chr12 GO:0006952 Not Cancer Driver No 55 0.238 45 17 0.378 0
KLRC3_ENST00000396439 KLRC3 Q07444 NKG2-E type II integral membrane protein chr12 GO:0006952 Not Cancer Driver No 37 0.154 43 4 0.093 0
KLRD1 KLRD1 Q13241 Natural killer cells antigen CD94 chr12 GO:0006952 Not Cancer Driver No 37 0.207 0 0 0.0 0
KLRG1_ENST00000266551 KLRG1 Q96E93 Killer cell lectin-like receptor subfamily G member 1 chr12 GO:0006952 Not Cancer Driver No 24 0.123 8 1 0.125 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0006952 Not Cancer Driver No 38 0.176 0 0 0.0 0
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 GO:0006952 Not Cancer Driver No 133 0.207 426 98 0.23 20
KRT6A KRT6A P02538 Keratin, type II cytoskeletal 6A chr12 GO:0006952 Not Cancer Driver No 127 0.225 138 35 0.254 24
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0006952 Not Cancer Driver No 46 0.176 16 6 0.375 0
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0006952 Not Cancer Driver No 84 0.175 6 0 0.0 0
LGALS3BP LGALS3BP Q08380 Galectin-3-binding protein chr17 GO:0006952 Not Cancer Driver No 62 0.106 9 0 0.0 0
LILRA1 LILRA1 O75019 Leukocyte immunoglobulin-like receptor subfamily A member 1 chr19 GO:0006952 Not Cancer Driver No 162 0.331 78 26 0.333 0
LILRA2 LILRA2 Q8N149 Leukocyte immunoglobulin-like receptor subfamily A member 2 chr19 GO:0006952 Not Cancer Driver No 163 0.337 137 44 0.321 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0006952 Not Cancer Driver No 148 0.248 235 50 0.213 0
LILRB5_ENST00000316219 LILRB5 O75023 Leukocyte immunoglobulin-like receptor subfamily B member 5 chr19 GO:0006952 Not Cancer Driver No 157 0.266 202 73 0.361 0
LSP1_ENST00000311604 LSP1 P33241 Lymphocyte-specific protein 1 chr11 GO:0006952 Not Cancer Driver No 44 0.13 337 43 0.128 0
LTF LTF P02788 Lactotransferrin chr3 GO:0006952 Not Cancer Driver No 131 0.185 21 4 0.19 0
LY96 LY96 Q9Y6Y9 Lymphocyte antigen 96 chr8 GO:0006952 Not Cancer Driver No 37 0.231 0 0 0.0 0
LYPD1 LYPD1 Q8N2G4 Ly6/PLAUR domain-containing protein 1 chr2 GO:0006952 Not Cancer Driver No 20 0.142 5 0 0.0 0
LYST LYST Q99698 Lysosomal-trafficking regulator chr1 GO:0006952 Not Cancer Driver No 465 0.122 608 87 0.143 4
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0006952 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAPK8IP2 MAPK8IP2 Q13387 C-Jun-amino-terminal kinase-interacting protein 2 chr22 GO:0006952 Not Cancer Driver No 49 0.059 568 27 0.048 0
MARCH2 MARCHF2 Q9P0N8 E3 ubiquitin-protein ligase MARCHF2 chr19 GO:0006952 Not Cancer Driver No 33 0.134 23 5 0.217 0
MASP1_ENST00000337774 MASP1 P48740 Mannan-binding lectin serine protease 1 chr3 GO:0006952 Not Cancer Driver No 142 0.203 72 14 0.194 0
MASP2 MASP2 O00187 Mannan-binding lectin serine protease 2 chr1 GO:0006952 Not Cancer Driver No 99 0.144 58 11 0.19 2
MBL2 MBL2 P11226 Mannose-binding protein C chr10 GO:0006952 Not Cancer Driver No 63 0.254 122 32 0.262 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0006952 Not Cancer Driver No 15 0.105 20 2 0.1 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0006952 Not Cancer Driver No 75 0.154 483 74 0.153 46
MFAP4_ENST00000299610 MFAP4 P55083 Microfibril-associated glycoprotein 4 chr17 GO:0006952 Not Cancer Driver No 35 0.137 0 0 0.0 0
MICU1 MICU1 Q9BPX6 Calcium uptake protein 1, mitochondrial chr10 GO:0006952 Not Cancer Driver No 50 0.105 97 18 0.186 0
MID2 MID2 Q9UJV3 Probable E3 ubiquitin-protein ligase MID2 chrX GO:0006952 Not Cancer Driver No 112 0.152 95 24 0.253 1
MNDA MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 GO:0006952 Not Cancer Driver No 180 0.442 172 76 0.442 0
MORC1 MORC1 Q86VD1 MORC family CW-type zinc finger protein 1 chr3 GO:0006952 Not Cancer Driver No 300 0.305 252 77 0.306 0
MPO MPO P05164 Myeloperoxidase chr17 GO:0006952 Not Cancer Driver No 149 0.2 52 12 0.231 3
MRGPRX1 MRGPRX1 Q96LB2 Mas-related G-protein coupled receptor member X1 chr11 GO:0006952 Not Cancer Driver No 123 0.382 0 0 0.0 0
MST1R MST1R Q04912 Macrophage-stimulating protein receptor chr3 GO:0006952 Not Cancer Driver No 178 0.127 182 27 0.148 1
MX1_ENST00000398598 MX1 P20591 Interferon-induced GTP-binding protein Mx1 chr21 GO:0006952 Not Cancer Driver No 88 0.133 74 10 0.135 0
MX2 MX2 P20592 Interferon-induced GTP-binding protein Mx2 chr21 GO:0006952 Not Cancer Driver No 96 0.134 159 25 0.157 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0006952 Census, Compendium Yes 37 0.125 47 1 0.021 2
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0006952 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCF2 NCF2 P19878 Neutrophil cytosol factor 2 chr1 GO:0006952 Not Cancer Driver No 97 0.184 183 34 0.186 14
NCR1 NCR1 O76036 Natural cytotoxicity triggering receptor 1 chr19 GO:0006952 Not Cancer Driver No 81 0.266 27 8 0.296 0
NCR2 NCR2 O95944 Natural cytotoxicity triggering receptor 2 chr6 GO:0006952 Not Cancer Driver No 63 0.228 60 14 0.233 0
NEUROD2 NEUROD2 Q15784 Neurogenic differentiation factor 2 chr17 GO:0006952 Not Cancer Driver No 26 0.068 210 14 0.067 2
NKG7 NKG7 Q16617 Protein NKG7 chr19 GO:0006952 Not Cancer Driver No 34 0.206 0 0 0.0 0
NLRP1_ENST00000572272 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 GO:0006952 Not Cancer Driver No 222 0.151 340 65 0.191 6
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0006952 Not Cancer Driver No 339 0.327 64 33 0.516 37
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0006952 Not Cancer Driver No 106 0.119 203 28 0.138 0
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0006952 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0006952 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0006952 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0006952 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0006952 Census, Compendium Yes 282 0.114 630 77 0.122 1
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0006952 Not Cancer Driver No 101 0.179 18 8 0.444 0
NOX3 NOX3 Q9HBY0 NADPH oxidase 3 chr6 GO:0006952 Not Cancer Driver No 118 0.208 3 0 0.0 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0006952 Not Cancer Driver No 123 0.213 0 0 0.0 0
NR2E1_ENST00000368986 NR2E1 Q9Y466 Nuclear receptor subfamily 2 group E member 1 chr6 GO:0006952 Not Cancer Driver No 75 0.195 57 6 0.105 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0006952 Not Cancer Driver No 10 0.122 82 10 0.122 0
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0006952 Not Cancer Driver No 67 0.168 71 12 0.169 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0006952 Not Cancer Driver No 37 0.107 71 12 0.169 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0006952 Not Cancer Driver No 107 0.268 58 27 0.466 0
OR2H2 OR2H2 O95918 Olfactory receptor 2H2 chr6 GO:0006952 Not Cancer Driver No 51 0.163 0 0 0.0 0
ORM1 ORM1 P02763 Alpha-1-acid glycoprotein 1 chr9 GO:0006952 Not Cancer Driver No 38 0.189 23 2 0.087 0
ORM2 ORM2 P19652 Alpha-1-acid glycoprotein 2 chr9 GO:0006952 Not Cancer Driver No 38 0.189 22 2 0.091 0
P2RY11 P2RY11 Q96G91 P2Y purinoceptor 11 chr19 GO:0006952 Not Cancer Driver No 47 0.126 31 1 0.032 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0006952 Not Cancer Driver No 109 0.408 142 62 0.437 0
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0006952 Not Cancer Driver No 13 0.129 0 0 0.0 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0006952 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0006952 Not Cancer Driver No 37 0.136 4 1 0.25 0
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0006952 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0006952 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLEKHM2 PLEKHM2 Q8IWE5 Pleckstrin homology domain-containing family M member 2 chr1 GO:0006952 Not Cancer Driver No 96 0.094 392 35 0.089 0
PLK5 PLK5 Q496M5 Inactive serine/threonine-protein kinase PLK5 chr19 GO:0006952 Not Cancer Driver No 8 0.024 215 4 0.019 0
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0006952 Not Cancer Driver No 43 0.135 92 13 0.141 0
PML PML P29590 Protein PML chr15 GO:0006952 Census, Compendium Yes 112 0.127 312 34 0.109 0
PNLIPRP2 PNLIPRP2 P54317 Pancreatic lipase-related protein 2 chr10 GO:0006952 Not Cancer Driver No 75 0.16 28 2 0.071 0
PNMA1 PNMA1 Q8ND90 Paraneoplastic antigen Ma1 chr14 GO:0006952 Not Cancer Driver No 48 0.136 56 9 0.161 0
PRCP_ENST00000313010 PRCP P42785 Lysosomal Pro-X carboxypeptidase chr11 GO:0006952 Not Cancer Driver No 58 0.117 0 0 0.0 0
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 GO:0006952 Not Cancer Driver No 22 0.111 40 5 0.125 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0006952 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRF1_ENST00000373209 PRF1 P14222 Perforin-1 chr10 GO:0006952 Census, Compendium Yes 122 0.22 145 36 0.248 8
PSG3 PSG3 Q16557 Pregnancy-specific beta-1-glycoprotein 3 chr19 GO:0006952 Not Cancer Driver No 139 0.325 66 17 0.258 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0006952 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0006952 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRCAP PTPRCAP Q14761 Protein tyrosine phosphatase receptor type C-associated protein chr11 GO:0006952 Not Cancer Driver No 21 0.102 120 16 0.133 0
RAB23_ENST00000317483 RAB23 Q9ULC3 Ras-related protein Rab-23 chr6 GO:0006952 Not Cancer Driver No 28 0.118 62 6 0.097 2
RAET1E RAET1E Q8TD07 Retinoic acid early transcript 1E chr6 GO:0006952 Not Cancer Driver No 40 0.152 0 0 0.0 0
RAET1G RAET1G Q6H3X3 UL-16 binding protein 5 chr6 GO:0006952 Not Cancer Driver No 41 0.123 62 10 0.161 0
RARRES2 RARRES2 Q99969 Retinoic acid receptor responder protein 2 chr7 GO:0006952 Not Cancer Driver No 16 0.098 14 2 0.143 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0006952 Not Cancer Driver No 96 0.12 191 12 0.063 1
RBMS3 RBMS3 Q6XE24 RNA-binding motif, single-stranded-interacting protein 3 chr3 GO:0006952 Not Cancer Driver No 87 0.199 278 57 0.205 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0006952 Not Cancer Driver No 49 0.098 151 19 0.126 2
REG3A_ENST00000305165 REG3A Q06141 Regenerating islet-derived protein 3-alpha chr2 GO:0006952 Not Cancer Driver No 93 0.531 19 10 0.526 0
REG3G REG3G Q6UW15 Regenerating islet-derived protein 3-gamma chr2 GO:0006952 Not Cancer Driver No 81 0.463 17 4 0.235 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0006952 Compendium Yes 75 0.136 400 48 0.12 0
RNASE2 RNASE2 P10153 Non-secretory ribonuclease chr14 GO:0006952 Not Cancer Driver No 30 0.186 20 4 0.2 0
RNASE3 RNASE3 P12724 Eosinophil cationic protein chr14 GO:0006952 Not Cancer Driver No 37 0.231 8 0 0.0 0
RNASE6 RNASE6 Q93091 Ribonuclease K6 chr14 GO:0006952 Not Cancer Driver No 26 0.173 0 0 0.0 0
RNASE8 RNASE8 Q8TDE3 Ribonuclease 8 chr14 GO:0006952 Not Cancer Driver No 18 0.117 17 2 0.118 0
RNF135 RNF135 Q8IUD6 E3 ubiquitin-protein ligase RNF135 chr17 GO:0006952 Not Cancer Driver No 40 0.093 139 11 0.079 0
RNF19B RNF19B Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B chr1 GO:0006952 Not Cancer Driver No 58 0.079 344 24 0.07 0
ROMO1_ENST00000397416 ROMO1 P60602 Reactive oxygen species modulator 1 chr20 GO:0006952 Not Cancer Driver No 9 0.114 0 0 0.0 0
RPL39 RPL39 P62891 60S ribosomal protein L39 chrX GO:0006952 Not Cancer Driver No 9 0.176 51 9 0.176 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0006952 Not Cancer Driver No 45 0.086 226 26 0.115 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:0006952 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:0006952 Not Cancer Driver No 18 0.158 76 7 0.092 0
SAA1 SAA1 P0DJI8 Serum amyloid A-1 protein chr11 GO:0006952 Not Cancer Driver No 23 0.189 25 5 0.2 0
SAA2_ENST00000529528 SAA2 P0DJI9 Serum amyloid A-2 protein chr11 GO:0006952 Not Cancer Driver No 31 0.254 39 12 0.308 0
SAA4 SAA4 P35542 Serum amyloid A-4 protein chr11 GO:0006952 Not Cancer Driver No 19 0.146 28 5 0.179 0
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0006952 Not Cancer Driver No 90 0.141 62 4 0.065 13
SENP7 SENP7 Q9BQF6 Sentrin-specific protease 7 chr3 GO:0006952 Not Cancer Driver No 149 0.142 523 73 0.14 0
SERPINA1 SERPINA1 P01009 Alpha-1-antitrypsin chr14 GO:0006952 Not Cancer Driver No 66 0.158 38 7 0.184 0
SERPINA3_ENST00000393080 SERPINA3 P01011 Alpha-1-antichymotrypsin chr14 GO:0006952 Not Cancer Driver No 117 0.277 18 10 0.556 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0006952 Not Cancer Driver No 62 0.126 112 21 0.188 1
SFTPD SFTPD P35247 Pulmonary surfactant-associated protein D chr10 GO:0006952 Not Cancer Driver No 66 0.176 274 53 0.193 0
SH2D1A SH2D1A O60880 SH2 domain-containing protein 1A chrX GO:0006952 Not Cancer Driver No 40 0.312 24 8 0.333 19
SIGIRR_ENST00000397632 SIGIRR Q6IA17 Single Ig IL-1-related receptor chr11 GO:0006952 Not Cancer Driver No 27 0.066 85 4 0.047 0
SLAMF7 SLAMF7 Q9NQ25 SLAM family member 7 chr1 GO:0006952 Not Cancer Driver No 66 0.197 53 14 0.264 0
SLC11A1 SLC11A1 P49279 Natural resistance-associated macrophage protein 1 chr2 GO:0006952 Not Cancer Driver No 79 0.144 47 5 0.106 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0006952 Not Cancer Driver No 69 0.132 17 4 0.235 1
SOCS6_ENST00000582322 SOCS6 O14544 Suppressor of cytokine signaling 6 chr18 GO:0006952 Not Cancer Driver No 81 0.151 299 48 0.161 0
SP140 SP140 Q13342 Nuclear body protein SP140 chr2 GO:0006952 Compendium Yes 198 0.228 458 123 0.269 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0006952 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPN_ENST00000395389 SPN P16150 Leukosialin chr16 GO:0006952 Not Cancer Driver No 46 0.115 357 35 0.098 0
SPON2_ENST00000431380 SPON2 Q9BUD6 Spondin-2 chr4 GO:0006952 Not Cancer Driver No 36 0.109 73 4 0.055 0
SSC5D SSC5D A1L4H1 Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D chr19 GO:0006952 Not Cancer Driver No 81 0.051 1194 70 0.059 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0006952 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT2 STAT2 P52630 Signal transducer and activator of transcription 2 chr12 GO:0006952 Not Cancer Driver No 90 0.106 178 22 0.124 2
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0006952 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT4_ENST00000358470 STAT4 Q14765 Signal transducer and activator of transcription 4 chr2 GO:0006952 Not Cancer Driver No 154 0.206 143 36 0.252 0
STAT5A_ENST00000590949 STAT5A P42229 Signal transducer and activator of transcription 5A chr17 GO:0006952 Not Cancer Driver No 89 0.112 125 14 0.112 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0006952 Census, Compendium Yes 93 0.118 144 19 0.132 5
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0006952 Census, Compendium Yes 106 0.125 325 44 0.135 0
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0006952 Not Cancer Driver No 69 0.17 28 2 0.071 0
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0006952 Compendium Yes 68 0.082 102 6 0.059 5
TFR2_ENST00000223051 TFR2 Q9UP52 Transferrin receptor protein 2 chr7 GO:0006952 Not Cancer Driver No 94 0.117 168 20 0.119 3
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0006952 Census Yes 89 0.117 80 6 0.075 1
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0006952 Not Cancer Driver No 188 0.161 320 58 0.181 0
TIAL1_ENST00000436547 TIAL1 Q01085 Nucleolysin TIAR chr10 GO:0006952 Not Cancer Driver No 45 0.12 122 12 0.098 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0006952 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0006952 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 GO:0006952 Not Cancer Driver No 85 0.134 625 83 0.133 0
TPSAB1 TPSAB1 Q15661 Tryptase alpha/beta-1 chr16 GO:0006952 Not Cancer Driver No 40 0.145 28 6 0.214 0
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:0006952 Not Cancer Driver No 86 0.462 129 67 0.519 0
TREM1 TREM1 Q9NP99 Triggering receptor expressed on myeloid cells 1 chr6 GO:0006952 Not Cancer Driver No 45 0.192 63 7 0.111 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0006952 Not Cancer Driver No 43 0.187 27 2 0.074 1
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0006952 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIM11 TRIM11 Q96F44 E3 ubiquitin-protein ligase TRIM11 chr1 GO:0006952 Not Cancer Driver No 58 0.124 132 14 0.106 0
TRIM13_ENST00000378182 TRIM13 O60858 E3 ubiquitin-protein ligase TRIM13 chr13 GO:0006952 Not Cancer Driver No 53 0.13 1 0 0.0 0
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 GO:0006952 Not Cancer Driver No 69 0.148 79 11 0.139 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 GO:0006952 Not Cancer Driver No 85 0.179 49 7 0.143 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0006952 Not Cancer Driver No 59 0.094 225 20 0.089 0
TRIM26 TRIM26 Q12899 Tripartite motif-containing protein 26 chr6 GO:0006952 Not Cancer Driver No 67 0.124 153 16 0.105 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 GO:0006952 Census Yes 59 0.115 87 11 0.126 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0006952 Not Cancer Driver No 87 0.104 430 41 0.095 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0006952 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM35 TRIM35 Q9UPQ4 E3 ubiquitin-protein ligase TRIM35 chr8 GO:0006952 Not Cancer Driver No 66 0.134 69 9 0.13 0
TRIM5 TRIM5 Q9C035 Tripartite motif-containing protein 5 chr11 GO:0006952 Not Cancer Driver No 71 0.144 77 11 0.143 0
TRIM8 TRIM8 Q9BZR9 E3 ubiquitin-protein ligase TRIM8 chr10 GO:0006952 Not Cancer Driver No 60 0.109 209 29 0.139 0
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0006952 Not Cancer Driver No 93 0.111 155 18 0.116 0
TSPAN32 TSPAN32 Q96QS1 Tetraspanin-32 chr11 GO:0006952 Not Cancer Driver No 33 0.103 8 3 0.375 0
TUBB TUBB P07437 Tubulin beta chain chr6 GO:0006952 Not Cancer Driver No 40 0.09 63 11 0.175 5
TUBB4B TUBB4B P68371 Tubulin beta-4B chain chr9 GO:0006952 Not Cancer Driver No 52 0.117 65 11 0.169 2
TUSC2 TUSC2 O75896 Tumor suppressor candidate 2 chr3 GO:0006952 Not Cancer Driver No 10 0.091 31 3 0.097 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0006952 Not Cancer Driver No 24 0.212 28 8 0.286 0
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0006952 Not Cancer Driver No 100 0.188 11 2 0.182 55
ULBP1 ULBP1 Q9BZM6 UL16-binding protein 1 chr6 GO:0006952 Not Cancer Driver No 48 0.197 24 4 0.167 0
ULBP2 ULBP2 Q9BZM5 UL16-binding protein 2 chr6 GO:0006952 Not Cancer Driver No 33 0.134 25 2 0.08 0
ULBP3 ULBP3 Q9BZM4 UL16-binding protein 3 chr6 GO:0006952 Not Cancer Driver No 34 0.139 14 1 0.071 0
UMOD_ENST00000302509 UMOD P07911 Uromodulin chr16 GO:0006952 Not Cancer Driver No 125 0.195 12 1 0.083 37
USP46 USP46 P62068 Ubiquitin carboxyl-terminal hydrolase 46 chr4 GO:0006952 Not Cancer Driver No 48 0.131 28 4 0.143 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 GO:0006952 Not Cancer Driver No 188 0.254 110 28 0.255 0
VEZF1 VEZF1 Q14119 Vascular endothelial zinc finger 1 chr17 GO:0006952 Not Cancer Driver No 56 0.107 332 32 0.096 0
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0006952 Not Cancer Driver No 88 0.172 20 5 0.25 0
VSIG4 VSIG4 Q9Y279 V-set and immunoglobulin domain-containing protein 4 chrX GO:0006952 Not Cancer Driver No 73 0.183 70 13 0.186 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0006952 Census, Compendium Yes 75 0.149 400 55 0.138 30
WDR83 WDR83 Q9BRX9 WD repeat domain-containing protein 83 chr19 GO:0006952 Not Cancer Driver No 28 0.089 35 3 0.086 0
ZDHHC1 ZDHHC1 Q8WTX9 Palmitoyltransferase ZDHHC1 chr16 GO:0006952 Not Cancer Driver No 46 0.095 167 11 0.066 0
ZDHHC11 ZDHHC11 Q9H8X9 Palmitoyltransferase ZDHHC11 chr5 GO:0006952 Not Cancer Driver No 68 0.165 76 24 0.316 0
ZG16 ZG16 O60844 Zymogen granule membrane protein 16 chr16 GO:0006952 Not Cancer Driver No 5 0.03 7 1 0.143 0
ZNF148_ENST00000485866 ZNF148 Q9UQR1 Zinc finger protein 148 chr3 GO:0006952 Compendium Yes 125 0.157 600 88 0.147 0