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Total number of protein in "GO:0005126" GO term:  228

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0005126 Not Cancer Driver No 80 0.097 182 17 0.093 0
AMH AMH P03971 Muellerian-inhibiting factor chr19 GO:0005126 Not Cancer Driver No 19 0.034 207 4 0.019 9
BAMBI BAMBI Q13145 BMP and activin membrane-bound inhibitor homolog chr10 GO:0005126 Not Cancer Driver No 42 0.162 31 7 0.226 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0005126 Not Cancer Driver No 47 0.19 79 19 0.241 1
BEX3_ENST00000372635 BEX3 Q00994 Protein BEX3 chrX GO:0005126 Not Cancer Driver No 19 0.171 98 17 0.173 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:0005126 Not Cancer Driver No 23 0.118 74 9 0.122 0
C10orf99 GPR15L Q6UWK7 Protein GPR15L chr10 GO:0005126 Not Cancer Driver No 11 0.136 0 0 0.0 0
C5 C5 P01031 Complement C5 chr9 GO:0005126 Not Cancer Driver No 192 0.115 84 9 0.107 0
CADM4 CADM4 Q8NFZ8 Cell adhesion molecule 4 chr19 GO:0005126 Not Cancer Driver No 48 0.124 94 9 0.096 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0005126 Census Yes 32 0.116 62 5 0.081 0
CASP8AP2 CASP8AP2 Q9UKL3 CASP8-associated protein 2 chr6 GO:0005126 Not Cancer Driver No 219 0.11 1501 178 0.119 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0005126 Census, Compendium Yes 142 0.296 106 12 0.113 1
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0005126 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCL1 CCL1 P22362 C-C motif chemokine 1 chr17 GO:0005126 Not Cancer Driver No 27 0.281 0 0 0.0 0
CCL11 CCL11 P51671 Eotaxin chr17 GO:0005126 Not Cancer Driver No 18 0.186 14 3 0.214 0
CCL13 CCL13 Q99616 C-C motif chemokine 13 chr17 GO:0005126 Not Cancer Driver No 15 0.153 1 0 0.0 0
CCL17_ENST00000616880 CCL17 Q92583 C-C motif chemokine 17 chr16 GO:0005126 Not Cancer Driver No 10 0.106 0 0 0.0 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0005126 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0005126 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCL20 CCL20 P78556 C-C motif chemokine 20 chr2 GO:0005126 Not Cancer Driver No 16 0.167 0 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0005126 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCL22 CCL22 O00626 C-C motif chemokine 22 chr16 GO:0005126 Not Cancer Driver No 19 0.204 0 0 0.0 0
CCL24_ENST00000222902 CCL24 O00175 C-C motif chemokine 24 chr7 GO:0005126 Not Cancer Driver No 25 0.21 23 3 0.13 0
CCL25 CCL25 O15444 C-C motif chemokine 25 chr19 GO:0005126 Not Cancer Driver No 20 0.133 26 6 0.231 0
CCL26_ENST00000005180 CCL26 Q9Y258 C-C motif chemokine 26 chr7 GO:0005126 Not Cancer Driver No 9 0.096 0 0 0.0 0
CCL27 CCL27 Q9Y4X3 C-C motif chemokine 27 chr9 GO:0005126 Not Cancer Driver No 15 0.134 0 0 0.0 0
CCL28 CCL28 Q9NRJ3 C-C motif chemokine 28 chr5 GO:0005126 Not Cancer Driver No 17 0.134 48 8 0.167 0
CCL7 CCL7 P80098 C-C motif chemokine 7 chr17 GO:0005126 Not Cancer Driver No 30 0.303 13 3 0.231 0
CCL8 CCL8 P80075 C-C motif chemokine 8 chr17 GO:0005126 Not Cancer Driver No 17 0.172 0 0 0.0 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0005126 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCRL2_ENST00000399036 CCRL2 O00421 C-C chemokine receptor-like 2 chr3 GO:0005126 Not Cancer Driver No 44 0.128 20 5 0.25 0
CD2AP CD2AP Q9Y5K6 CD2-associated protein chr6 GO:0005126 Not Cancer Driver No 80 0.125 456 60 0.132 0
CD300LF_ENST00000326165 CD300LF Q8TDQ1 CMRF35-like molecule 1 chr17 GO:0005126 Not Cancer Driver No 36 0.124 88 11 0.125 0
CD40LG CD40LG P29965 CD40 ligand chrX GO:0005126 Not Cancer Driver No 56 0.215 24 7 0.292 32
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0005126 Not Cancer Driver No 144 0.184 305 55 0.18 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0005126 Not Cancer Driver No 40 0.083 44 2 0.045 0
CKLF CKLF Q9UBR5 Chemokine-like factor chr16 GO:0005126 Not Cancer Driver No 20 0.132 0 0 0.0 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0005126 Not Cancer Driver No 22 0.098 42 4 0.095 1
CNIH4 CNIH4 Q9P003 Protein cornichon homolog 4 chr1 GO:0005126 Not Cancer Driver No 13 0.094 0 0 0.0 0
CNTF CNTF P26441 Ciliary neurotrophic factor chr11 GO:0005126 Not Cancer Driver No 41 0.205 34 5 0.147 0
CRLF1 CRLF1 O75462 Cytokine receptor-like factor 1 chr19 GO:0005126 Not Cancer Driver No 51 0.121 101 7 0.069 14
CRLF2_ENST00000381566 CRLF2 Q9HC73 Cytokine receptor-like factor 2 chrX GO:0005126 Census Yes 54 0.146 62 3 0.048 0
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0005126 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0005126 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0005126 Not Cancer Driver No 20 0.097 7 0 0.0 0
CSH1 CSH1 P0DML2 Chorionic somatomammotropin hormone 1 chr17 GO:0005126 Not Cancer Driver No 33 0.152 23 2 0.087 0
CSH2 CSH2 P0DML3 Chorionic somatomammotropin hormone 2 chr17 GO:0005126 Not Cancer Driver No 53 0.244 23 3 0.13 0
CSHL1 CSHL1 Q14406 Chorionic somatomammotropin hormone-like 1 chr17 GO:0005126 Not Cancer Driver No 63 0.284 18 5 0.278 0
CTF1 CTF1 Q16619 Cardiotrophin-1 chr16 GO:0005126 Not Cancer Driver No 6 0.03 90 4 0.044 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0005126 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0005126 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL1 CXCL1 P09341 Growth-regulated alpha protein chr4 GO:0005126 Not Cancer Driver No 20 0.187 18 4 0.222 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0005126 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL11 CXCL11 O14625 C-X-C motif chemokine 11 chr4 GO:0005126 Not Cancer Driver No 13 0.138 0 0 0.0 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0005126 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0005126 Not Cancer Driver No 11 0.101 0 0 0.0 0
CXCL14 CXCL14 O95715 C-X-C motif chemokine 14 chr5 GO:0005126 Not Cancer Driver No 15 0.135 0 0 0.0 0
CXCL2 CXCL2 P19875 C-X-C motif chemokine 2 chr4 GO:0005126 Not Cancer Driver No 11 0.103 15 5 0.333 0
CXCL3 CXCL3 P19876 C-X-C motif chemokine 3 chr4 GO:0005126 Not Cancer Driver No 11 0.103 8 0 0.0 0
CXCL5 CXCL5 P42830 C-X-C motif chemokine 5 chr4 GO:0005126 Not Cancer Driver No 25 0.219 1 0 0.0 0
CXCL6 CXCL6 P80162 C-X-C motif chemokine 6 chr4 GO:0005126 Not Cancer Driver No 17 0.149 9 1 0.111 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0005126 Not Cancer Driver No 17 0.172 0 0 0.0 0
CXCL9 CXCL9 Q07325 C-X-C motif chemokine 9 chr4 GO:0005126 Not Cancer Driver No 32 0.256 38 16 0.421 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0005126 Not Cancer Driver No 131 0.11 681 68 0.1 0
DDT_ENST00000350608 DDT P30046 D-dopachrome decarboxylase chr22 GO:0005126 Not Cancer Driver No 4 0.034 0 0 0.0 0
DEFB1 DEFB1 P60022 Beta-defensin 1 chr8 GO:0005126 Not Cancer Driver No 8 0.118 0 0 0.0 0
DEFB106B DEFB106B Q8N104 Beta-defensin 106 chr8 GO:0005126 Not Cancer Driver No 15 0.231 0 0 0.0 0
DEFB130A DEFB130A P0DP74 Beta-defensin 130A chr8 GO:0005126 Not Cancer Driver No 2 0.025 5 0 0.0 0
DEFB130B DEFB130B P0DP73 Beta-defensin 130B chr8 GO:0005126 Not Cancer Driver No 1 0.013 5 0 0.0 0
DEFB4B DEFB4B O15263 Beta-defensin 4A chr8 GO:0005126 Not Cancer Driver No 1 0.016 0 0 0.0 0
EBI3 EBI3 Q14213 Interleukin-27 subunit beta chr19 GO:0005126 Not Cancer Driver No 32 0.14 10 1 0.1 0
ECM1_ENST00000369047 ECM1 Q16610 Extracellular matrix protein 1 chr1 GO:0005126 Not Cancer Driver No 91 0.169 219 28 0.128 1
EDA EDA Q92838 Ectodysplasin-A chrX GO:0005126 Not Cancer Driver No 73 0.187 243 43 0.177 71
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0005126 Not Cancer Driver No 34 0.149 25 6 0.24 0
ENG ENG P17813 Endoglin chr9 GO:0005126 Not Cancer Driver No 60 0.091 114 15 0.132 32
EPO EPO P01588 Erythropoietin chr7 GO:0005126 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERAP1_ENST00000443439 ERAP1 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 chr5 GO:0005126 Not Cancer Driver No 78 0.083 70 2 0.029 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0005126 Not Cancer Driver No 26 0.125 45 10 0.222 1
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 GO:0005126 Not Cancer Driver No 65 0.231 94 18 0.191 1
FEM1B FEM1B Q9UK73 Protein fem-1 homolog B chr15 GO:0005126 Not Cancer Driver No 69 0.11 33 3 0.091 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0005126 Not Cancer Driver No 71 0.104 101 10 0.099 0
FKBP1A FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 GO:0005126 Not Cancer Driver No 15 0.139 39 7 0.179 0
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0005126 Not Cancer Driver No 69 0.136 415 58 0.14 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0005126 Census, Compendium Yes 111 0.251 364 87 0.239 2
GH1 GH1 P01241 Somatotropin chr17 GO:0005126 Not Cancer Driver No 54 0.249 24 9 0.375 15
GH2_ENST00000423893 GH2 P01242 Growth hormone variant chr17 GO:0005126 Not Cancer Driver No 55 0.253 12 9 0.75 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 GO:0005126 Not Cancer Driver No 28 0.129 10 1 0.1 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0005126 Not Cancer Driver No 25 0.136 77 12 0.156 0
IFNA10 IFNA10 P01566 Interferon alpha-10 chr9 GO:0005126 Not Cancer Driver No 40 0.212 1 0 0.0 0
IFNA13_ENST00000449498 IFNA13 P01562 Interferon alpha-1/13 chr9 GO:0005126 Not Cancer Driver No 39 0.206 2 0 0.0 0
IFNA14 IFNA14 P01570 Interferon alpha-14 chr9 GO:0005126 Not Cancer Driver No 39 0.206 1 1 1.0 0
IFNA16 IFNA16 P05015 Interferon alpha-16 chr9 GO:0005126 Not Cancer Driver No 61 0.323 1 0 0.0 0
IFNA17 IFNA17 P01571 Interferon alpha-17 chr9 GO:0005126 Not Cancer Driver No 37 0.196 0 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0005126 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNA21 IFNA21 P01568 Interferon alpha-21 chr9 GO:0005126 Not Cancer Driver No 34 0.18 0 0 0.0 0
IFNA4 IFNA4 P05014 Interferon alpha-4 chr9 GO:0005126 Not Cancer Driver No 39 0.206 1 0 0.0 0
IFNA5 IFNA5 P01569 Interferon alpha-5 chr9 GO:0005126 Not Cancer Driver No 36 0.19 1 0 0.0 0
IFNA6 IFNA6 P05013 Interferon alpha-6 chr9 GO:0005126 Not Cancer Driver No 28 0.148 4 0 0.0 0
IFNA7 IFNA7 P01567 Interferon alpha-7 chr9 GO:0005126 Not Cancer Driver No 43 0.228 1 1 1.0 0
IFNA8 IFNA8 P32881 Interferon alpha-8 chr9 GO:0005126 Not Cancer Driver No 43 0.228 0 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0005126 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNE IFNE Q86WN2 Interferon epsilon chr9 GO:0005126 Not Cancer Driver No 30 0.144 17 4 0.235 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0005126 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNK IFNK Q9P0W0 Interferon kappa chr9 GO:0005126 Not Cancer Driver No 17 0.082 23 0 0.0 0
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:0005126 Not Cancer Driver No 24 0.12 49 8 0.163 0
IFNW1 IFNW1 P05000 Interferon omega-1 chr9 GO:0005126 Not Cancer Driver No 32 0.164 10 3 0.3 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0005126 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL11 IL11 P20809 Interleukin-11 chr19 GO:0005126 Not Cancer Driver No 19 0.095 69 8 0.116 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0005126 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0005126 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL13 IL13 P35225 Interleukin-13 chr5 GO:0005126 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL13RA1 IL13RA1 P78552 Interleukin-13 receptor subunit alpha-1 chrX GO:0005126 Not Cancer Driver No 58 0.136 33 7 0.212 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0005126 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL17F IL17F Q96PD4 Interleukin-17F chr6 GO:0005126 Not Cancer Driver No 42 0.258 34 11 0.324 1
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0005126 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0005126 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0005126 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1F10_ENST00000341010 IL1F10 Q8WWZ1 Interleukin-1 family member 10 chr2 GO:0005126 Not Cancer Driver No 30 0.197 10 1 0.1 0
IL1RAP_ENST00000447382 IL1RAP Q9NPH3 Interleukin-1 receptor accessory protein chr3 GO:0005126 Not Cancer Driver No 79 0.139 50 11 0.22 0
IL1RN_ENST00000409930 IL1RN P18510 Interleukin-1 receptor antagonist protein chr2 GO:0005126 Not Cancer Driver No 34 0.192 17 7 0.412 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0005126 Census Yes 24 0.157 6 1 0.167 0
IL20_ENST00000367096 IL20 Q9NYY1 Interleukin-20 chr1 GO:0005126 Not Cancer Driver No 30 0.17 0 0 0.0 0
IL21 IL21 Q9HBE4 Interleukin-21 chr4 GO:0005126 Not Cancer Driver No 34 0.21 70 18 0.257 1
IL22_ENST00000328087 IL22 Q9GZX6 Interleukin-22 chr12 GO:0005126 Not Cancer Driver No 32 0.179 0 0 0.0 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0005126 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0005126 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL25 IL25 Q9H293 Interleukin-25 chr14 GO:0005126 Not Cancer Driver No 30 0.169 50 8 0.16 0
IL27 IL27 Q8NEV9 Interleukin-27 subunit alpha chr16 GO:0005126 Not Cancer Driver No 37 0.152 27 1 0.037 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0005126 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL3 IL3 P08700 Interleukin-3 chr5 GO:0005126 Not Cancer Driver No 25 0.164 22 3 0.136 0
IL31 IL31 Q6EBC2 Interleukin-31 chr12 GO:0005126 Not Cancer Driver No 19 0.116 25 4 0.16 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0005126 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL36A IL36A Q9UHA7 Interleukin-36 alpha chr2 GO:0005126 Not Cancer Driver No 44 0.278 13 3 0.231 0
IL36B IL36B Q9NZH7 Interleukin-36 beta chr2 GO:0005126 Not Cancer Driver No 53 0.323 32 8 0.25 0
IL36G IL36G Q9NZH8 Interleukin-36 gamma chr2 GO:0005126 Not Cancer Driver No 35 0.207 23 5 0.217 0
IL36RN_ENST00000346807 IL36RN Q9UBH0 Interleukin-36 receptor antagonist protein chr2 GO:0005126 Not Cancer Driver No 34 0.219 7 4 0.571 4
IL37 IL37 Q9NZH6 Interleukin-37 chr2 GO:0005126 Not Cancer Driver No 56 0.257 71 13 0.183 1
IL4 IL4 P05112 Interleukin-4 chr5 GO:0005126 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL5 IL5 P05113 Interleukin-5 chr5 GO:0005126 Not Cancer Driver No 13 0.097 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0005126 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0005126 Not Cancer Driver No 55 0.118 165 23 0.139 1
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0005126 Census, Compendium Yes 102 0.111 315 40 0.127 2
IL7 IL7 P13232 Interleukin-7 chr8 GO:0005126 Not Cancer Driver No 29 0.164 19 4 0.211 0
IL9 IL9 P15248 Interleukin-9 chr5 GO:0005126 Not Cancer Driver No 12 0.083 4 0 0.0 0
INHBC INHBC P55103 Inhibin beta C chain chr12 GO:0005126 Not Cancer Driver No 52 0.148 35 3 0.086 0
IRAK4_ENST00000551736 IRAK4 Q9NWZ3 Interleukin-1 receptor-associated kinase 4 chr12 GO:0005126 Not Cancer Driver No 68 0.148 116 20 0.172 2
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0005126 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 GO:0005126 Not Cancer Driver No 127 0.121 201 29 0.144 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0005126 Not Cancer Driver No 124 0.157 66 5 0.076 30
JAK1 JAK1 P23458 Tyrosine-protein kinase JAK1 chr1 GO:0005126 Census, Compendium Yes 147 0.127 120 7 0.058 2
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0005126 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0005126 Census, Compendium Yes 167 0.149 63 10 0.159 7
KITLG KITLG P21583 Kit ligand chr12 GO:0005126 Not Cancer Driver No 48 0.176 61 9 0.148 1
LEFTY1 LEFTY1 O75610 Left-right determination factor 1 chr1 GO:0005126 Not Cancer Driver No 55 0.15 65 8 0.123 0
LEFTY2 LEFTY2 O00292 Left-right determination factor 2 chr1 GO:0005126 Not Cancer Driver No 38 0.104 54 4 0.074 1
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0005126 Not Cancer Driver No 25 0.124 0 0 0.0 0
LIFR_ENST00000453190 LIFR P42702 Leukemia inhibitory factor receptor chr5 GO:0005126 Census, Compendium Yes 247 0.225 259 56 0.216 1
LRG1 LRG1 P02750 Leucine-rich alpha-2-glycoprotein chr19 GO:0005126 Not Cancer Driver No 63 0.182 29 8 0.276 0
MADD MADD Q8WXG6 MAP kinase-activating death domain protein chr11 GO:0005126 Not Cancer Driver No 207 0.126 723 81 0.112 4
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0005126 Not Cancer Driver No 4 0.035 0 0 0.0 0
MSMP MSMP Q1L6U9 Prostate-associated microseminoprotein chr9 GO:0005126 Not Cancer Driver No 15 0.108 27 0 0.0 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0005126 Census, Compendium Yes 37 0.125 47 1 0.021 2
NARS NARS1 O43776 Asparagine--tRNA ligase, cytoplasmic chr18 GO:0005126 Not Cancer Driver No 50 0.091 103 16 0.155 4
NES NES P48681 Nestin chr1 GO:0005126 Not Cancer Driver No 271 0.167 1474 253 0.172 0
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0005126 Not Cancer Driver No 66 0.274 93 25 0.269 1
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0005126 Not Cancer Driver No 20 0.096 179 17 0.095 2
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0005126 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTF4 NTF4 P34130 Neurotrophin-4 chr19 GO:0005126 Not Cancer Driver No 21 0.1 56 4 0.071 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0005126 Census, Compendium Yes 168 0.211 57 8 0.14 25
OSM OSM P13725 Oncostatin-M chr22 GO:0005126 Not Cancer Driver No 43 0.171 114 24 0.211 0
OSMR OSMR Q99650 Oncostatin-M-specific receptor subunit beta chr5 GO:0005126 Not Cancer Driver No 167 0.171 145 22 0.152 5
PDCL3 PDCL3 Q9H2J4 Phosducin-like protein 3 chr2 GO:0005126 Not Cancer Driver No 48 0.201 73 13 0.178 0
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0005126 Not Cancer Driver No 13 0.129 0 0 0.0 0
PF4V1 PF4V1 P10720 Platelet factor 4 variant chr4 GO:0005126 Not Cancer Driver No 18 0.173 6 2 0.333 0
PGF_ENST00000405431 PGF P49763 Placenta growth factor chr14 GO:0005126 Not Cancer Driver No 30 0.136 72 10 0.139 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0005126 Not Cancer Driver No 83 0.11 419 45 0.107 2
PIDD1 PIDD1 Q9HB75 p53-induced death domain-containing protein 1 chr11 GO:0005126 Not Cancer Driver No 93 0.102 137 14 0.102 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0005126 Census, Compendium Yes 154 0.213 268 61 0.228 2
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0005126 Census, Compendium Yes 158 0.122 186 21 0.113 0
PPBP PPBP P02775 Platelet basic protein chr4 GO:0005126 Not Cancer Driver No 30 0.234 21 8 0.381 0
PRL PRL P01236 Prolactin chr6 GO:0005126 Not Cancer Driver No 49 0.216 22 1 0.045 0
PRLR PRLR P16471 Prolactin receptor chr5 GO:0005126 Not Cancer Driver No 154 0.248 282 70 0.248 2
PXDN PXDN Q92626 Peroxidasin homolog chr2 GO:0005126 Not Cancer Driver No 332 0.224 307 77 0.251 1
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0005126 Not Cancer Driver No 16 0.082 39 4 0.103 0
RASL11B RASL11B Q9BPW5 Ras-like protein family member 11B chr4 GO:0005126 Not Cancer Driver No 24 0.097 33 4 0.121 0
RHEX RHEX Q6ZWK4 Regulator of hemoglobinization and erythroid cell expansion protein chr1 GO:0005126 Not Cancer Driver No 35 0.203 116 27 0.233 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0005126 Compendium Yes 82 0.122 277 39 0.141 4
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 GO:0005126 Not Cancer Driver No 44 0.139 33 2 0.061 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0005126 Not Cancer Driver No 39 0.131 17 2 0.118 0
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:0005126 Census, Compendium Yes 48 0.083 333 19 0.057 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 GO:0005126 Not Cancer Driver No 84 0.144 397 58 0.146 0
SIVA1 SIVA1 O15304 Apoptosis regulatory protein Siva chr14 GO:0005126 Not Cancer Driver No 20 0.114 20 6 0.3 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0005126 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0005126 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0005126 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0005126 Not Cancer Driver No 40 0.094 139 0 0.0 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:0005126 Not Cancer Driver No 33 0.081 85 7 0.082 0
SOCS2_ENST00000536696 SOCS2 O14508 Suppressor of cytokine signaling 2 chr12 GO:0005126 Not Cancer Driver No 32 0.162 61 2 0.033 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0005126 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:0005126 Not Cancer Driver No 73 0.175 228 43 0.189 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0005126 Not Cancer Driver No 66 0.224 103 18 0.175 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0005126 Not Cancer Driver No 131 0.175 144 25 0.174 26
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0005126 Census Yes 96 0.151 131 27 0.206 5
TFF2 TFF2 Q03403 Trefoil factor 2 chr21 GO:0005126 Not Cancer Driver No 16 0.124 0 0 0.0 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0005126 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0005126 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0005126 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0005126 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0005126 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0005126 Not Cancer Driver No 129 0.152 268 41 0.153 0
TGFBRAP1 TGFBRAP1 Q8WUH2 Transforming growth factor-beta receptor-associated protein 1 chr2 GO:0005126 Not Cancer Driver No 127 0.148 37 8 0.216 0
TIMM50_ENST00000607714 TIMM50 Q3ZCQ8 Mitochondrial import inner membrane translocase subunit TIM50 chr19 GO:0005126 Not Cancer Driver No 39 0.11 75 7 0.093 0
TLR5_ENST00000366881 TLR5 O60602 Toll-like receptor 5 chr1 GO:0005126 Not Cancer Driver No 148 0.172 16 3 0.188 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0005126 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMBIM1_ENST00000396809 TMBIM1 Q969X1 Protein lifeguard 3 chr2 GO:0005126 Not Cancer Driver No 30 0.096 83 8 0.096 0
TOLLIP TOLLIP Q9H0E2 Toll-interacting protein chr11 GO:0005126 Not Cancer Driver No 38 0.139 81 12 0.148 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0005126 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRIP6 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 GO:0005126 Not Cancer Driver No 62 0.13 268 19 0.071 0
TSLP TSLP Q969D9 Thymic stromal lymphopoietin chr5 GO:0005126 Not Cancer Driver No 27 0.17 16 0 0.0 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 GO:0005126 Not Cancer Driver No 148 0.125 213 29 0.136 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:0005126 Not Cancer Driver No 136 0.139 259 39 0.151 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0005126 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFB VEGFB P49765 Vascular endothelial growth factor B chr11 GO:0005126 Not Cancer Driver No 25 0.121 125 22 0.176 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0005126 Not Cancer Driver No 128 0.305 37 12 0.324 0
VEGFD VEGFD O43915 Vascular endothelial growth factor D chrX GO:0005126 Not Cancer Driver No 59 0.167 33 6 0.182 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0005126 Not Cancer Driver No 28 0.246 35 11 0.314 0
XCL2 XCL2 Q9UBD3 Cytokine SCM-1 beta chr1 GO:0005126 Not Cancer Driver No 20 0.175 35 5 0.143 0
YARS YARS1 P54577 Tyrosine--tRNA ligase, cytoplasmic chr1 GO:0005126 Not Cancer Driver No 62 0.117 109 9 0.083 3