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Total number of protein in "GO:0004842" GO term:  238

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AKTIP_ENST00000570004 AKTIP Q9H8T0 AKT-interacting protein chr16 GO:0004842 Not Cancer Driver No 33 0.113 95 10 0.105 0
AMFR AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 GO:0004842 Not Cancer Driver No 73 0.114 229 30 0.131 0
ANAPC11_ENST00000579978 ANAPC11 Q9NYG5 Anaphase-promoting complex subunit 11 chr17 GO:0004842 Not Cancer Driver No 7 0.083 0 0 0.0 0
ANAPC4_ENST00000315368 ANAPC4 Q9UJX5 Anaphase-promoting complex subunit 4 chr4 GO:0004842 Not Cancer Driver No 70 0.087 54 1 0.019 0
ANKRD39 ANKRD39 Q53RE8 Ankyrin repeat domain-containing protein 39 chr2 GO:0004842 Not Cancer Driver No 19 0.104 38 2 0.053 0
AREL1 AREL1 O15033 Apoptosis-resistant E3 ubiquitin protein ligase 1 chr14 GO:0004842 Not Cancer Driver No 104 0.126 92 10 0.109 0
ARIH1 ARIH1 Q9Y4X5 E3 ubiquitin-protein ligase ARIH1 chr15 GO:0004842 Not Cancer Driver No 46 0.083 119 7 0.059 0
ARIH2 ARIH2 O95376 E3 ubiquitin-protein ligase ARIH2 chr3 GO:0004842 Not Cancer Driver No 64 0.13 85 11 0.129 0
ASB4 ASB4 Q9Y574 Ankyrin repeat and SOCS box protein 4 chr7 GO:0004842 Not Cancer Driver No 82 0.192 19 1 0.053 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0004842 Census Yes 96 0.124 384 49 0.128 0
BCOR BCOR Q6W2J9 BCL-6 corepressor chrX GO:0004842 Census, Compendium Yes 291 0.166 1285 226 0.176 1
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0004842 Not Cancer Driver No 69 0.112 83 9 0.108 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 GO:0004842 Census, Compendium Yes 77 0.127 98 16 0.163 0
BIRC6 BIRC6 Q9NR09 Baculoviral IAP repeat-containing protein 6 chr2 GO:0004842 Census, Compendium Yes 640 0.132 1312 170 0.13 0
BIRC7 BIRC7 Q96CA5 Baculoviral IAP repeat-containing protein 7 chr20 GO:0004842 Not Cancer Driver No 52 0.174 136 22 0.162 0
BRAP BRAP Q7Z569 BRCA1-associated protein chr12 GO:0004842 Not Cancer Driver No 70 0.118 192 24 0.125 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0004842 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0004842 Not Cancer Driver No 80 0.132 45 4 0.089 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0004842 Census, Compendium Yes 115 0.127 512 56 0.109 4
CBLL1 CBLL1 Q75N03 E3 ubiquitin-protein ligase Hakai chr7 GO:0004842 Not Cancer Driver No 72 0.147 373 49 0.131 0
CDC23 CDC23 Q9UJX2 Cell division cycle protein 23 homolog chr5 GO:0004842 Not Cancer Driver No 57 0.095 45 6 0.133 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 GO:0004842 Not Cancer Driver No 26 0.11 95 11 0.116 0
CHFR CHFR Q96EP1 E3 ubiquitin-protein ligase CHFR chr12 GO:0004842 Not Cancer Driver No 85 0.128 341 54 0.158 0
CNOT4_ENST00000315544 CNOT4 O95628 CCR4-NOT transcription complex subunit 4 chr7 GO:0004842 Not Cancer Driver No 73 0.127 359 35 0.097 0
COP1 COP1 Q8NHY2 E3 ubiquitin-protein ligase COP1 chr1 GO:0004842 Not Cancer Driver No 106 0.145 147 11 0.075 0
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0004842 Census, Compendium Yes 123 0.16 167 23 0.138 3
CUL5 CUL5 Q93034 Cullin-5 chr11 GO:0004842 Not Cancer Driver No 97 0.124 5 1 0.2 0
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 GO:0004842 Census, Compendium Yes 45 0.105 70 5 0.071 2
DTL DTL Q9NZJ0 Denticleless protein homolog chr1 GO:0004842 Not Cancer Driver No 73 0.1 331 49 0.148 0
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0004842 Not Cancer Driver No 86 0.116 260 24 0.092 0
DTX4 DTX4 Q9Y2E6 E3 ubiquitin-protein ligase DTX4 chr11 GO:0004842 Not Cancer Driver No 84 0.136 323 57 0.176 0
DZIP3_ENST00000463306 DZIP3 Q86Y13 E3 ubiquitin-protein ligase DZIP3 chr3 GO:0004842 Not Cancer Driver No 177 0.147 370 68 0.184 0
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 GO:0004842 Not Cancer Driver No 25 0.063 53 8 0.151 7
FANCL_ENST00000233741 FANCL Q9NW38 E3 ubiquitin-protein ligase FANCL chr2 GO:0004842 Not Cancer Driver No 47 0.125 11 0 0.0 0
FBXL14 FBXL14 Q8N1E6 F-box/LRR-repeat protein 14 chr12 GO:0004842 Not Cancer Driver No 33 0.079 7 1 0.143 0
FBXL3 FBXL3 Q9UKT7 F-box/LRR-repeat protein 3 chr13 GO:0004842 Not Cancer Driver No 49 0.114 30 6 0.2 1
FBXL5 FBXL5 Q9UKA1 F-box/LRR-repeat protein 5 chr4 GO:0004842 Not Cancer Driver No 80 0.116 70 7 0.1 0
FBXL6 FBXL6 Q8N531 F-box/LRR-repeat protein 6 chr8 GO:0004842 Not Cancer Driver No 48 0.089 114 5 0.044 0
FBXO10 FBXO10 Q9UK96 F-box only protein 10 chr9 GO:0004842 Not Cancer Driver No 106 0.111 223 23 0.103 0
FBXO11 FBXO11 Q86XK2 F-box only protein 11 chr2 GO:0004842 Census, Compendium Yes 113 0.122 242 22 0.091 8
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 GO:0004842 Not Cancer Driver No 21 0.071 75 1 0.013 0
FBXO21 FBXO21 O94952 F-box only protein 21 chr12 GO:0004842 Not Cancer Driver No 73 0.116 17 3 0.176 0
FBXO22 FBXO22 Q8NEZ5 F-box only protein 22 chr15 GO:0004842 Not Cancer Driver No 65 0.161 15 3 0.2 0
FBXO24_ENST00000241071 FBXO24 O75426 F-box only protein 24 chr7 GO:0004842 Not Cancer Driver No 119 0.205 55 10 0.182 0
FBXO25 FBXO25 Q8TCJ0 F-box only protein 25 chr8 GO:0004842 Not Cancer Driver No 33 0.09 20 0 0.0 0
FBXO3 FBXO3 Q9UK99 F-box only protein 3 chr11 GO:0004842 Not Cancer Driver No 56 0.119 51 7 0.137 0
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0004842 Not Cancer Driver No 55 0.142 68 7 0.103 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0004842 Not Cancer Driver No 75 0.144 243 38 0.156 1
FBXO9 FBXO9 Q9UK97 F-box only protein 9 chr6 GO:0004842 Not Cancer Driver No 49 0.11 110 7 0.064 0
FBXW11 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 GO:0004842 Not Cancer Driver No 75 0.138 20 3 0.15 7
FBXW2 FBXW2 Q9UKT8 F-box/WD repeat-containing protein 2 chr9 GO:0004842 Not Cancer Driver No 49 0.108 0 0 0.0 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0004842 Not Cancer Driver No 68 0.114 120 4 0.033 0
G2E3 G2E3 Q7L622 G2/M phase-specific E3 ubiquitin-protein ligase chr14 GO:0004842 Not Cancer Driver No 79 0.112 26 6 0.231 0
HACE1 HACE1 Q8IYU2 E3 ubiquitin-protein ligase HACE1 chr6 GO:0004842 Not Cancer Driver No 126 0.139 103 12 0.117 0
HECTD2_ENST00000298068 HECTD2 Q5U5R9 Probable E3 ubiquitin-protein ligase HECTD2 chr10 GO:0004842 Not Cancer Driver No 85 0.11 134 23 0.172 0
HECTD3 HECTD3 Q5T447 E3 ubiquitin-protein ligase HECTD3 chr1 GO:0004842 Not Cancer Driver No 88 0.102 55 5 0.091 0
HERC1 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 GO:0004842 Not Cancer Driver No 487 0.1 1344 129 0.096 1
HERC3 HERC3 Q15034 Probable E3 ubiquitin-protein ligase HERC3 chr4 GO:0004842 Not Cancer Driver No 112 0.107 56 7 0.125 0
HERC4 HERC4 Q5GLZ8 Probable E3 ubiquitin-protein ligase HERC4 chr10 GO:0004842 Not Cancer Driver No 111 0.105 40 2 0.05 0
HERC5 HERC5 Q9UII4 E3 ISG15--protein ligase HERC5 chr4 GO:0004842 Not Cancer Driver No 124 0.121 118 12 0.102 0
HERC6 HERC6 Q8IVU3 Probable E3 ubiquitin-protein ligase HERC6 chr4 GO:0004842 Not Cancer Driver No 146 0.143 132 16 0.121 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX GO:0004842 Not Cancer Driver No 669 0.153 2091 329 0.157 21
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0004842 Not Cancer Driver No 95 0.105 335 42 0.125 0
KCTD10 KCTD10 Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 chr12 GO:0004842 Not Cancer Driver No 68 0.217 73 19 0.26 0
KCTD13 KCTD13 Q8WZ19 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 chr16 GO:0004842 Not Cancer Driver No 33 0.1 95 10 0.105 0
KLHL13_ENST00000262820 KLHL13 Q9P2N7 Kelch-like protein 13 chrX GO:0004842 Not Cancer Driver No 159 0.243 51 17 0.333 0
KLHL20 KLHL20 Q9Y2M5 Kelch-like protein 20 chr1 GO:0004842 Not Cancer Driver No 83 0.136 143 17 0.119 0
KLHL21 KLHL21 Q9UJP4 Kelch-like protein 21 chr1 GO:0004842 Not Cancer Driver No 43 0.072 63 7 0.111 0
KLHL42 KLHL42 Q9P2K6 Kelch-like protein 42 chr12 GO:0004842 Not Cancer Driver No 48 0.095 57 4 0.07 0
KLHL9 KLHL9 Q9P2J3 Kelch-like protein 9 chr9 GO:0004842 Not Cancer Driver No 70 0.113 26 4 0.154 0
LMO7_ENST00000357063 LMO7 Q8WWI1 LIM domain only protein 7 chr13 GO:0004842 Not Cancer Driver No 267 0.159 1102 188 0.171 0
LNX1 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 GO:0004842 Not Cancer Driver No 117 0.161 261 40 0.153 0
LNX2 LNX2 Q8N448 Ligand of Numb protein X 2 chr13 GO:0004842 Not Cancer Driver No 85 0.123 277 35 0.126 0
LRSAM1_ENST00000373322 LRSAM1 Q6UWE0 E3 ubiquitin-protein ligase LRSAM1 chr9 GO:0004842 Not Cancer Driver No 86 0.119 240 30 0.125 1
MAEA MAEA Q7L5Y9 E3 ubiquitin-protein transferase MAEA chr4 GO:0004842 Not Cancer Driver No 58 0.146 64 5 0.078 0
MAGEL2 MAGEL2 Q9UJ55 MAGE-like protein 2 chr15 GO:0004842 Not Cancer Driver No 178 0.143 1010 118 0.117 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0004842 Census, Compendium Yes 75 0.091 139 12 0.086 1
MARCH2 MARCHF2 Q9P0N8 E3 ubiquitin-protein ligase MARCHF2 chr19 GO:0004842 Not Cancer Driver No 33 0.134 23 5 0.217 0
MARCH3 MARCHF3 Q86UD3 E3 ubiquitin-protein ligase MARCHF3 chr5 GO:0004842 Not Cancer Driver No 26 0.103 5 1 0.2 0
MARCH4 MARCHF4 Q9P2E8 E3 ubiquitin-protein ligase MARCHF4 chr2 GO:0004842 Not Cancer Driver No 93 0.227 155 31 0.2 0
MARCH6 MARCHF6 O60337 E3 ubiquitin-protein ligase MARCHF6 chr5 GO:0004842 Not Cancer Driver No 114 0.125 114 13 0.114 0
MARCH8_ENST00000319836 MARCHF8 Q5T0T0 E3 ubiquitin-protein ligase MARCHF8 chr10 GO:0004842 Not Cancer Driver No 31 0.107 71 8 0.113 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0004842 Census, Compendium Yes 56 0.114 297 37 0.125 0
MGRN1_ENST00000399577 MGRN1 O60291 E3 ubiquitin-protein ligase MGRN1 chr16 GO:0004842 Not Cancer Driver No 76 0.138 228 37 0.162 0
MIB1 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 GO:0004842 Not Cancer Driver No 122 0.121 282 34 0.121 1
MIB2_ENST00000504599 MIB2 Q96AX9 E3 ubiquitin-protein ligase MIB2 chr1 GO:0004842 Not Cancer Driver No 88 0.092 307 31 0.101 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0004842 Not Cancer Driver No 48 0.136 16 2 0.125 0
MYLIP MYLIP Q8WY64 E3 ubiquitin-protein ligase MYLIP chr6 GO:0004842 Not Cancer Driver No 56 0.126 11 2 0.182 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 GO:0004842 Not Cancer Driver No 126 0.129 463 60 0.13 4
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0004842 Not Cancer Driver No 62 0.108 153 11 0.072 0
NHLRC1 NHLRC1 Q6VVB1 E3 ubiquitin-protein ligase NHLRC1 chr6 GO:0004842 Not Cancer Driver No 66 0.167 18 3 0.167 22
NSMCE1 NSMCE1 Q8WV22 Non-structural maintenance of chromosomes element 1 homolog chr16 GO:0004842 Not Cancer Driver No 40 0.15 31 8 0.258 0
PDZRN3 PDZRN3 Q9UPQ7 E3 ubiquitin-protein ligase PDZRN3 chr3 GO:0004842 Not Cancer Driver No 234 0.22 699 195 0.279 0
PELI1 PELI1 Q96FA3 E3 ubiquitin-protein ligase pellino homolog 1 chr2 GO:0004842 Not Cancer Driver No 47 0.112 167 17 0.102 0
PELI2 PELI2 Q9HAT8 E3 ubiquitin-protein ligase pellino homolog 2 chr14 GO:0004842 Not Cancer Driver No 80 0.19 162 38 0.235 0
PEX12 PEX12 O00623 Peroxisome assembly protein 12 chr17 GO:0004842 Not Cancer Driver No 45 0.125 30 3 0.1 1
PJA2 PJA2 O43164 E3 ubiquitin-protein ligase Praja-2 chr5 GO:0004842 Not Cancer Driver No 80 0.113 598 66 0.11 0
PML PML P29590 Protein PML chr15 GO:0004842 Census, Compendium Yes 112 0.127 312 34 0.109 0
PPIL2_ENST00000335025 PPIL2 Q13356 RING-type E3 ubiquitin-protein ligase PPIL2 chr22 GO:0004842 Not Cancer Driver No 64 0.123 212 19 0.09 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0004842 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 GO:0004842 Not Cancer Driver No 71 0.141 109 16 0.147 0
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0004842 Not Cancer Driver No 204 0.196 208 43 0.207 36
RBBP6 RBBP6 Q7Z6E9 E3 ubiquitin-protein ligase RBBP6 chr16 GO:0004842 Not Cancer Driver No 229 0.128 1626 212 0.13 0
RBCK1 RBCK1 Q9BYM8 RanBP-type and C3HC4-type zinc finger-containing protein 1 chr20 GO:0004842 Not Cancer Driver No 52 0.102 140 14 0.1 2
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 GO:0004842 Not Cancer Driver No 10 0.093 18 1 0.056 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0004842 Not Cancer Driver No 158 0.139 796 115 0.144 0
RCHY1 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 GO:0004842 Not Cancer Driver No 33 0.126 23 0 0.0 0
RFPL1 RFPL1 O75677 Ret finger protein-like 1 chr22 GO:0004842 Not Cancer Driver No 73 0.23 28 5 0.179 0
RFPL2 RFPL2 O75678 Ret finger protein-like 2 chr22 GO:0004842 Not Cancer Driver No 77 0.204 71 21 0.296 0
RFPL3 RFPL3 O75679 Ret finger protein-like 3 chr22 GO:0004842 Not Cancer Driver No 85 0.268 28 3 0.107 0
RFPL4A RFPL4A A6NLU0 Ret finger protein-like 4A chr19 GO:0004842 Not Cancer Driver No 31 0.108 11 2 0.182 0
RFPL4AL1 RFPL4AL1 F8VTS6 Ret finger protein-like 4A-like protein 1 chr19 GO:0004842 Not Cancer Driver No 5 0.017 12 2 0.167 0
RLIM_ENST00000349225 RLIM Q9NVW2 E3 ubiquitin-protein ligase RLIM chrX GO:0004842 Not Cancer Driver No 106 0.17 545 94 0.172 4
RMND5A RMND5A Q9H871 E3 ubiquitin-protein transferase RMND5A chr2 GO:0004842 Not Cancer Driver No 46 0.118 0 0 0.0 0
RMND5B RMND5B Q96G75 E3 ubiquitin-protein transferase RMND5B chr5 GO:0004842 Not Cancer Driver No 34 0.087 0 0 0.0 0
RNF115 RNF115 Q9Y4L5 E3 ubiquitin-protein ligase RNF115 chr1 GO:0004842 Not Cancer Driver No 30 0.099 136 14 0.103 0
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 GO:0004842 Not Cancer Driver No 167 0.127 220 28 0.127 0
RNF130 RNF130 Q86XS8 E3 ubiquitin-protein ligase RNF130 chr5 GO:0004842 Not Cancer Driver No 45 0.107 43 5 0.116 0
RNF135 RNF135 Q8IUD6 E3 ubiquitin-protein ligase RNF135 chr17 GO:0004842 Not Cancer Driver No 40 0.093 139 11 0.079 0
RNF139 RNF139 Q8WU17 E3 ubiquitin-protein ligase RNF139 chr8 GO:0004842 Not Cancer Driver No 76 0.114 68 4 0.059 0
RNF13_ENST00000392894 RNF13 O43567 E3 ubiquitin-protein ligase RNF13 chr3 GO:0004842 Not Cancer Driver No 45 0.118 107 17 0.159 2
RNF141 RNF141 Q8WVD5 RING finger protein 141 chr11 GO:0004842 Not Cancer Driver No 28 0.122 48 4 0.083 0
RNF144B RNF144B Q7Z419 E3 ubiquitin-protein ligase RNF144B chr6 GO:0004842 Not Cancer Driver No 32 0.106 4 1 0.25 0
RNF146 RNF146 Q9NTX7 E3 ubiquitin-protein ligase RNF146 chr6 GO:0004842 Not Cancer Driver No 37 0.103 206 24 0.117 0
RNF152 RNF152 Q8N8N0 E3 ubiquitin-protein ligase RNF152 chr18 GO:0004842 Not Cancer Driver No 61 0.3 34 11 0.324 0
RNF167_ENST00000571816 RNF167 Q9H6Y7 E3 ubiquitin-protein ligase RNF167 chr17 GO:0004842 Not Cancer Driver No 35 0.1 102 18 0.176 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 GO:0004842 Not Cancer Driver No 77 0.135 471 66 0.14 0
RNF169 RNF169 Q8NCN4 E3 ubiquitin-protein ligase RNF169 chr11 GO:0004842 Not Cancer Driver No 52 0.073 637 46 0.072 0
RNF181 RNF181 Q9P0P0 E3 ubiquitin-protein ligase RNF181 chr2 GO:0004842 Not Cancer Driver No 15 0.098 63 8 0.127 0
RNF182 RNF182 Q8N6D2 E3 ubiquitin-protein ligase RNF182 chr6 GO:0004842 Not Cancer Driver No 44 0.178 12 2 0.167 0
RNF186 RNF186 Q9NXI6 E3 ubiquitin-protein ligase RNF186 chr1 GO:0004842 Not Cancer Driver No 27 0.119 11 3 0.273 0
RNF187_ENST00000639044 RNF187 Q5TA31 E3 ubiquitin-protein ligase RNF187 chr1 GO:0004842 Not Cancer Driver No 2 0.009 104 1 0.01 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 GO:0004842 Not Cancer Driver No 40 0.119 203 22 0.108 0
RNF20 RNF20 Q5VTR2 E3 ubiquitin-protein ligase BRE1A chr9 GO:0004842 Not Cancer Driver No 126 0.129 561 64 0.114 0
RNF208 RNF208 Q9H0X6 RING finger protein 208 chr9 GO:0004842 Not Cancer Driver No 20 0.077 113 9 0.08 0
RNF213 RNF213 Q63HN8 E3 ubiquitin-protein ligase RNF213 chr17 GO:0004842 Census, Compendium Yes 560 0.108 623 75 0.12 3
RNF214_ENST00000531452 RNF214 Q8ND24 RING finger protein 214 chr11 GO:0004842 Not Cancer Driver No 84 0.119 528 66 0.125 0
RNF217 RNF217 Q8TC41 E3 ubiquitin-protein ligase RNF217 chr6 GO:0004842 Not Cancer Driver No 70 0.129 203 13 0.064 0
RNF219 OBI1 Q5W0B1 ORC ubiquitin ligase 1 chr13 GO:0004842 Not Cancer Driver No 96 0.132 486 67 0.138 0
RNF220_ENST00000361799 RNF220 Q5VTB9 E3 ubiquitin-protein ligase RNF220 chr1 GO:0004842 Not Cancer Driver No 104 0.184 401 75 0.187 0
RNF25 RNF25 Q96BH1 E3 ubiquitin-protein ligase RNF25 chr2 GO:0004842 Not Cancer Driver No 56 0.122 285 42 0.147 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 GO:0004842 Not Cancer Driver No 142 0.132 319 45 0.141 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 GO:0004842 Not Cancer Driver No 14 0.074 117 7 0.06 0
RNF40 RNF40 O75150 E3 ubiquitin-protein ligase BRE1B chr16 GO:0004842 Not Cancer Driver No 132 0.132 645 80 0.124 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 GO:0004842 Not Cancer Driver No 44 0.139 33 2 0.061 0
RNF43_ENST00000577716 RNF43 Q68DV7 E3 ubiquitin-protein ligase RNF43 chr17 GO:0004842 Census, Compendium Yes 121 0.155 437 54 0.124 0
RNF5 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 GO:0004842 Not Cancer Driver No 17 0.094 69 3 0.043 0
RNF6 RNF6 Q9Y252 E3 ubiquitin-protein ligase RNF6 chr13 GO:0004842 Compendium Yes 91 0.133 601 87 0.145 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 GO:0004842 Not Cancer Driver No 56 0.115 226 29 0.128 0
RSPRY1_ENST00000394420 RSPRY1 Q96DX4 RING finger and SPRY domain-containing protein 1 chr16 GO:0004842 Not Cancer Driver No 64 0.111 98 18 0.184 1
SHARPIN SHARPIN Q9H0F6 Sharpin chr8 GO:0004842 Not Cancer Driver No 34 0.088 237 16 0.068 0
SHPRH SHPRH Q149N8 E3 ubiquitin-protein ligase SHPRH chr6 GO:0004842 Not Cancer Driver No 227 0.135 359 51 0.142 0
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:0004842 Not Cancer Driver No 35 0.124 28 2 0.071 5
SIAH2 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 GO:0004842 Not Cancer Driver No 48 0.148 68 3 0.044 0
SMURF1 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 GO:0004842 Not Cancer Driver No 89 0.118 256 31 0.121 0
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 GO:0004842 Not Cancer Driver No 87 0.116 242 28 0.116 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0004842 Not Cancer Driver No 35 0.116 112 14 0.125 12
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0004842 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TNFAIP1 TNFAIP1 Q13829 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 chr17 GO:0004842 Not Cancer Driver No 35 0.111 39 5 0.128 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0004842 Census, Compendium Yes 98 0.124 231 33 0.143 1
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 GO:0004842 Not Cancer Driver No 149 0.143 795 105 0.132 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0004842 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 GO:0004842 Compendium Yes 61 0.107 101 9 0.089 1
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0004842 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAF7 TRAF7 Q6Q0C0 E3 ubiquitin-protein ligase TRAF7 chr16 GO:0004842 Census Yes 76 0.113 120 14 0.117 4
TRAIP TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 GO:0004842 Not Cancer Driver No 63 0.134 240 33 0.138 1
TRIM13_ENST00000378182 TRIM13 O60858 E3 ubiquitin-protein ligase TRIM13 chr13 GO:0004842 Not Cancer Driver No 53 0.13 1 0 0.0 0
TRIM17_ENST00000366698 TRIM17 Q9Y577 E3 ubiquitin-protein ligase TRIM17 chr1 GO:0004842 Not Cancer Driver No 64 0.134 127 19 0.15 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 GO:0004842 Not Cancer Driver No 85 0.179 49 7 0.143 0
TRIM23 TRIM23 P36406 E3 ubiquitin-protein ligase TRIM23 chr5 GO:0004842 Not Cancer Driver No 91 0.159 39 2 0.051 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0004842 Not Cancer Driver No 59 0.094 225 20 0.089 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 GO:0004842 Census Yes 59 0.115 87 11 0.126 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0004842 Not Cancer Driver No 87 0.104 430 41 0.095 0
TRIM2_ENST00000437508 TRIM2 Q9C040 Tripartite motif-containing protein 2 chr4 GO:0004842 Not Cancer Driver No 86 0.116 238 38 0.16 1
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0004842 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM33 TRIM33 Q9UPN9 E3 ubiquitin-protein ligase TRIM33 chr1 GO:0004842 Census, Compendium Yes 110 0.098 617 51 0.083 0
TRIM36 TRIM36 Q9NQ86 E3 ubiquitin-protein ligase TRIM36 chr5 GO:0004842 Not Cancer Driver No 106 0.146 89 21 0.236 1
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 GO:0004842 Not Cancer Driver No 119 0.123 492 60 0.122 3
TRIM4 TRIM4 Q9C037 E3 ubiquitin-protein ligase TRIM4 chr7 GO:0004842 Not Cancer Driver No 51 0.102 40 5 0.125 0
TRIM45 TRIM45 Q9H8W5 Tripartite motif-containing protein 45 chr1 GO:0004842 Not Cancer Driver No 71 0.122 58 9 0.155 0
TRIM47 TRIM47 Q96LD4 E3 ubiquitin-protein ligase TRIM47 chr17 GO:0004842 Not Cancer Driver No 38 0.06 202 9 0.045 0
TRIM5 TRIM5 Q9C035 Tripartite motif-containing protein 5 chr11 GO:0004842 Not Cancer Driver No 71 0.144 77 11 0.143 0
TRIM56 TRIM56 Q9BRZ2 E3 ubiquitin-protein ligase TRIM56 chr7 GO:0004842 Not Cancer Driver No 110 0.146 217 36 0.166 0
TRIM62 TRIM62 Q9BVG3 E3 ubiquitin-protein ligase TRIM62 chr1 GO:0004842 Not Cancer Driver No 58 0.122 80 14 0.175 0
TRIM68 TRIM68 Q6AZZ1 E3 ubiquitin-protein ligase TRIM68 chr11 GO:0004842 Not Cancer Driver No 74 0.153 37 7 0.189 0
TRIM69_ENST00000329464 TRIM69 Q86WT6 E3 ubiquitin-protein ligase TRIM69 chr15 GO:0004842 Not Cancer Driver No 78 0.156 62 15 0.242 0
TRIM71 TRIM71 Q2Q1W2 E3 ubiquitin-protein ligase TRIM71 chr3 GO:0004842 Not Cancer Driver No 124 0.143 163 21 0.129 2
TSPAN17_ENST00000515708 TSPAN17 Q96FV3 Tetraspanin-17 chr5 GO:0004842 Not Cancer Driver No 23 0.085 0 0 0.0 0
TTC3_ENST00000355666 TTC3 P53804 E3 ubiquitin-protein ligase TTC3 chr21 GO:0004842 Not Cancer Driver No 255 0.126 723 83 0.115 0
UBA7 UBA7 P41226 Ubiquitin-like modifier-activating enzyme 7 chr3 GO:0004842 Not Cancer Driver No 92 0.091 166 15 0.09 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX GO:0004842 Compendium Yes 35 0.23 67 13 0.194 2
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0004842 Not Cancer Driver No 13 0.086 68 6 0.088 0
UBE2C UBE2C O00762 Ubiquitin-conjugating enzyme E2 C chr20 GO:0004842 Not Cancer Driver No 13 0.073 40 0 0.0 0
UBE2D1 UBE2D1 P51668 Ubiquitin-conjugating enzyme E2 D1 chr10 GO:0004842 Not Cancer Driver No 13 0.088 14 0 0.0 0
UBE2D2 UBE2D2 P62837 Ubiquitin-conjugating enzyme E2 D2 chr5 GO:0004842 Compendium Yes 19 0.129 13 1 0.077 0
UBE2D3_ENST00000394801 UBE2D3 P61077 Ubiquitin-conjugating enzyme E2 D3 chr4 GO:0004842 Not Cancer Driver No 21 0.143 13 4 0.308 0
UBE2D4 UBE2D4 Q9Y2X8 Ubiquitin-conjugating enzyme E2 D4 chr7 GO:0004842 Not Cancer Driver No 13 0.088 21 1 0.048 0
UBE2E1 UBE2E1 P51965 Ubiquitin-conjugating enzyme E2 E1 chr3 GO:0004842 Not Cancer Driver No 21 0.109 78 10 0.128 0
UBE2E2_ENST00000425792 UBE2E2 Q96LR5 Ubiquitin-conjugating enzyme E2 E2 chr3 GO:0004842 Not Cancer Driver No 28 0.139 90 15 0.167 0
UBE2E3_ENST00000602710 UBE2E3 Q969T4 Ubiquitin-conjugating enzyme E2 E3 chr2 GO:0004842 Not Cancer Driver No 34 0.164 97 14 0.144 0
UBE2G1 UBE2G1 P62253 Ubiquitin-conjugating enzyme E2 G1 chr17 GO:0004842 Not Cancer Driver No 9 0.053 39 2 0.051 0
UBE2G2 UBE2G2 P60604 Ubiquitin-conjugating enzyme E2 G2 chr21 GO:0004842 Not Cancer Driver No 24 0.145 22 3 0.136 0
UBE2H UBE2H P62256 Ubiquitin-conjugating enzyme E2 H chr7 GO:0004842 Not Cancer Driver No 20 0.109 55 11 0.2 0
UBE2J1 UBE2J1 Q9Y385 Ubiquitin-conjugating enzyme E2 J1 chr6 GO:0004842 Not Cancer Driver No 33 0.104 158 20 0.127 0
UBE2J2_ENST00000349431 UBE2J2 Q8N2K1 Ubiquitin-conjugating enzyme E2 J2 chr1 GO:0004842 Not Cancer Driver No 42 0.162 51 7 0.137 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0004842 Not Cancer Driver No 24 0.12 33 3 0.091 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0004842 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE2L5_ENST00000436446 UBE2L5 A0A1B0GUS4 Ubiquitin-conjugating enzyme E2 L5 chr13 GO:0004842 Not Cancer Driver No 1 0.006 42 0 0.0 0
UBE2L6 UBE2L6 O14933 Ubiquitin/ISG15-conjugating enzyme E2 L6 chr11 GO:0004842 Not Cancer Driver No 19 0.124 7 1 0.143 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 GO:0004842 Not Cancer Driver No 30 0.164 32 6 0.188 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:0004842 Not Cancer Driver No 25 0.164 24 3 0.125 0
UBE2O UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 GO:0004842 Not Cancer Driver No 129 0.1 716 68 0.095 0
UBE2Q1 UBE2Q1 Q7Z7E8 Ubiquitin-conjugating enzyme E2 Q1 chr1 GO:0004842 Not Cancer Driver No 45 0.107 173 16 0.092 0
UBE2Q2 UBE2Q2 Q8WVN8 Ubiquitin-conjugating enzyme E2 Q2 chr15 GO:0004842 Not Cancer Driver No 35 0.093 122 10 0.082 0
UBE2QL1 UBE2QL1 A1L167 Ubiquitin-conjugating enzyme E2Q-like protein 1 chr5 GO:0004842 Not Cancer Driver No 16 0.099 4 0 0.0 0
UBE2R2 UBE2R2 Q712K3 Ubiquitin-conjugating enzyme E2 R2 chr9 GO:0004842 Not Cancer Driver No 28 0.118 104 15 0.144 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 GO:0004842 Not Cancer Driver No 25 0.113 102 12 0.118 0
UBE2T UBE2T Q9NPD8 Ubiquitin-conjugating enzyme E2 T chr1 GO:0004842 Not Cancer Driver No 12 0.061 97 9 0.093 1
UBE2U_ENST00000611228 UBE2U Q5VVX9 Ubiquitin-conjugating enzyme E2 U chr1 GO:0004842 Not Cancer Driver No 38 0.118 66 1 0.015 0
UBE2W_ENST00000602593 UBE2W Q96B02 Ubiquitin-conjugating enzyme E2 W chr8 GO:0004842 Not Cancer Driver No 19 0.126 26 5 0.192 0
UBE2Z UBE2Z Q9H832 Ubiquitin-conjugating enzyme E2 Z chr17 GO:0004842 Not Cancer Driver No 27 0.076 140 10 0.071 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0004842 Not Cancer Driver No 141 0.161 136 22 0.162 0
UBE4A_ENST00000252108 UBE4A Q14139 Ubiquitin conjugation factor E4 A chr11 GO:0004842 Not Cancer Driver No 120 0.113 121 17 0.14 0
UBE4B UBE4B O95155 Ubiquitin conjugation factor E4 B chr1 GO:0004842 Not Cancer Driver No 158 0.121 434 49 0.113 0
UBOX5 UBOX5 O94941 RING finger protein 37 chr20 GO:0004842 Not Cancer Driver No 62 0.115 190 24 0.126 0
UBR3 UBR3 Q6ZT12 E3 ubiquitin-protein ligase UBR3 chr2 GO:0004842 Not Cancer Driver No 154 0.082 339 28 0.083 0
UBR4 UBR4 Q5T4S7 E3 ubiquitin-protein ligase UBR4 chr1 GO:0004842 Not Cancer Driver No 565 0.109 1066 119 0.112 0
UBR5 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 GO:0004842 Census, Compendium Yes 340 0.121 1296 162 0.125 0
UHRF1_ENST00000616255 UHRF1 Q96T88 E3 ubiquitin-protein ligase UHRF1 chr19 GO:0004842 Not Cancer Driver No 97 0.122 353 49 0.139 0
UHRF2 UHRF2 Q96PU4 E3 ubiquitin-protein ligase UHRF2 chr9 GO:0004842 Not Cancer Driver No 88 0.11 253 22 0.087 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:0004842 Census, Compendium Yes 142 0.667 117 36 0.308 133
WDSUB1_ENST00000359774 WDSUB1 Q8N9V3 WD repeat, SAM and U-box domain-containing protein 1 chr2 GO:0004842 Not Cancer Driver No 50 0.105 17 2 0.118 0
WWP1 WWP1 Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 chr8 GO:0004842 Not Cancer Driver No 139 0.151 431 75 0.174 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 GO:0004842 Not Cancer Driver No 112 0.129 422 57 0.135 0
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0004842 Not Cancer Driver No 89 0.179 55 6 0.109 0
ZFP91 ZFP91 Q96JP5 E3 ubiquitin-protein ligase ZFP91 chr11 GO:0004842 Not Cancer Driver No 85 0.149 383 55 0.144 0
ZNRF1 ZNRF1 Q8ND25 E3 ubiquitin-protein ligase ZNRF1 chr16 GO:0004842 Not Cancer Driver No 22 0.097 115 3 0.026 0
ZNRF3 ZNRF3 Q9ULT6 E3 ubiquitin-protein ligase ZNRF3 chr22 GO:0004842 Census, Compendium Yes 94 0.1 510 51 0.1 0