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Total number of protein in "GO:0003690" GO term:  266

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0003690 Census, Compendium Yes 139 0.123 604 73 0.121 2
AFF3_ENST00000317233 AFF3 P51826 AF4/FMR2 family member 3 chr2 GO:0003690 Census, Compendium Yes 248 0.202 1019 206 0.202 6
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0003690 Not Cancer Driver No 129 0.152 351 75 0.214 0
AIM2 AIM2 O14862 Interferon-inducible protein AIM2 chr1 GO:0003690 Not Cancer Driver No 73 0.213 78 22 0.282 0
AKAP8 AKAP8 O43823 A-kinase anchor protein 8 chr19 GO:0003690 Not Cancer Driver No 88 0.127 566 78 0.138 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0003690 Not Cancer Driver No 34 0.107 103 14 0.136 0
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 GO:0003690 Not Cancer Driver No 36 0.101 101 6 0.059 9
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0003690 Not Cancer Driver No 71 0.113 332 40 0.12 0
ARNTL2 ARNTL2 Q8WYA1 Aryl hydrocarbon receptor nuclear translocator-like protein 2 chr12 GO:0003690 Not Cancer Driver No 79 0.124 264 38 0.144 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0003690 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASCL2 ASCL2 Q99929 Achaete-scute homolog 2 chr11 GO:0003690 Not Cancer Driver No 2 0.01 166 1 0.006 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0003690 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0003690 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0003690 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATF7_ENST00000456903 ATF7 P17544 Cyclic AMP-dependent transcription factor ATF-7 chr12 GO:0003690 Not Cancer Driver No 45 0.093 468 45 0.096 0
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0003690 Not Cancer Driver No 31 0.097 254 23 0.091 0
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 GO:0003690 Not Cancer Driver No 10 0.112 11 2 0.182 1
BAZ2A BAZ2A Q9UIF9 Bromodomain adjacent to zinc finger domain protein 2A chr12 GO:0003690 Not Cancer Driver No 186 0.098 1283 118 0.092 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0003690 Census, Compendium Yes 134 0.19 328 67 0.204 0
BEND3_ENST00000369042 BEND3 Q5T5X7 BEN domain-containing protein 3 chr6 GO:0003690 Not Cancer Driver No 104 0.126 311 44 0.141 0
BHLHE40 BHLHE40 O14503 Class E basic helix-loop-helix protein 40 chr3 GO:0003690 Not Cancer Driver No 52 0.126 242 31 0.128 0
BHLHE41 BHLHE41 Q9C0J9 Class E basic helix-loop-helix protein 41 chr12 GO:0003690 Not Cancer Driver No 21 0.044 213 10 0.047 0
BNC1 BNC1 Q01954 Zinc finger protein basonuclin-1 chr15 GO:0003690 Not Cancer Driver No 195 0.196 530 111 0.209 0
BNC2 BNC2 Q6ZN30 Zinc finger protein basonuclin-2 chr9 GO:0003690 Not Cancer Driver No 242 0.22 682 150 0.22 1
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 GO:0003690 Not Cancer Driver No 90 0.133 399 45 0.113 4
BRF2 BRF2 Q9HAW0 Transcription factor IIIB 50 kDa subunit chr8 GO:0003690 Not Cancer Driver No 40 0.095 138 13 0.094 0
CAMTA1 CAMTA1 Q9Y6Y1 Calmodulin-binding transcription activator 1 chr1 GO:0003690 Census, Compendium Yes 300 0.179 883 152 0.172 0
CAMTA2_ENST00000348066 CAMTA2 O94983 Calmodulin-binding transcription activator 2 chr17 GO:0003690 Not Cancer Driver No 148 0.123 613 84 0.137 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0003690 Not Cancer Driver No 3 0.009 276 2 0.007 0
CENPB CENPB P07199 Major centromere autoantigen B chr20 GO:0003690 Not Cancer Driver No 64 0.107 374 39 0.104 0
CENPC CENPC Q03188 Centromere protein C chr4 GO:0003690 Not Cancer Driver No 96 0.102 790 84 0.106 0
CENPS CENPS Q8N2Z9 Centromere protein S chr1 GO:0003690 Not Cancer Driver No 16 0.116 65 7 0.108 0
CENPX_ENST00000392359 CENPX A8MT69 Centromere protein X chr17 GO:0003690 Not Cancer Driver No 4 0.049 0 0 0.0 0
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0003690 Not Cancer Driver No 50 0.096 173 7 0.04 0
CGGBP1_ENST00000309534 CGGBP1 Q9UFW8 CGG triplet repeat-binding protein 1 chr3 GO:0003690 Not Cancer Driver No 18 0.108 105 11 0.105 0
CIART CIART Q8N365 Circadian-associated transcriptional repressor chr1 GO:0003690 Not Cancer Driver No 59 0.153 272 40 0.147 0
CLOCK CLOCK O15516 Circadian locomoter output cycles protein kaput chr4 GO:0003690 Not Cancer Driver No 83 0.098 458 38 0.083 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0003690 Census Yes 25 0.076 277 23 0.083 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0003690 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0003690 Census Yes 68 0.131 372 50 0.134 0
CREB3L2 CREB3L2 Q70SY1 Cyclic AMP-responsive element-binding protein 3-like protein 2 chr7 GO:0003690 Census Yes 61 0.117 364 46 0.126 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:0003690 Not Cancer Driver No 96 0.208 338 67 0.198 1
CREB3L4_ENST00000271889 CREB3L4 Q8TEY5 Cyclic AMP-responsive element-binding protein 3-like protein 4 chr1 GO:0003690 Not Cancer Driver No 55 0.139 241 27 0.112 0
CREB5 CREB5 Q02930 Cyclic AMP-responsive element-binding protein 5 chr7 GO:0003690 Not Cancer Driver No 92 0.181 494 89 0.18 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0003690 Not Cancer Driver No 76 0.13 91 5 0.055 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0003690 Not Cancer Driver No 154 0.159 280 55 0.196 1
DDX60 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 GO:0003690 Not Cancer Driver No 224 0.131 131 12 0.092 0
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0003690 Not Cancer Driver No 53 0.075 125 12 0.096 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0003690 Compendium Yes 182 0.143 331 42 0.127 0
DMC1 DMC1 Q14565 Meiotic recombination protein DMC1/LIM15 homolog chr22 GO:0003690 Not Cancer Driver No 39 0.115 49 5 0.102 0
E4F1 E4F1 Q66K89 Transcription factor E4F1 chr16 GO:0003690 Not Cancer Driver No 84 0.107 462 46 0.1 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0003690 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0003690 Not Cancer Driver No 78 0.144 501 72 0.144 0
ELK3 ELK3 P41970 ETS domain-containing protein Elk-3 chr12 GO:0003690 Not Cancer Driver No 58 0.143 163 16 0.098 0
ERCC5 ERCC5 P28715 DNA excision repair protein ERCC-5 chr13 GO:0003690 Census Yes 175 0.148 816 121 0.148 6
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0003690 Census, Compendium Yes 121 0.203 195 27 0.138 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 GO:0003690 Not Cancer Driver No 90 0.17 92 11 0.12 1
ESRRG_ENST00000408911 ESRRG P62508 Estrogen-related receptor gamma chr1 GO:0003690 Not Cancer Driver No 135 0.295 76 29 0.382 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0003690 Census, Compendium Yes 120 0.161 284 44 0.155 11
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0003690 Not Cancer Driver No 139 0.133 192 32 0.167 0
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 GO:0003690 Census Yes 35 0.092 111 11 0.099 0
FIGLA FIGLA Q6QHK4 Factor in the germline alpha chr2 GO:0003690 Not Cancer Driver No 22 0.1 154 17 0.11 0
FOS FOS P01100 Protein c-Fos chr14 GO:0003690 Not Cancer Driver No 45 0.118 245 33 0.135 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0003690 Census, Compendium Yes 111 0.251 364 87 0.239 2
GBX2 GBX2 P52951 Homeobox protein GBX-2 chr2 GO:0003690 Not Cancer Driver No 43 0.124 243 31 0.128 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0003690 Not Cancer Driver No 95 0.152 258 43 0.167 2
GTF2A1 GTF2A1 P52655 Transcription initiation factor IIA subunit 1 chr14 GO:0003690 Not Cancer Driver No 49 0.13 260 38 0.146 0
GTF2B GTF2B Q00403 Transcription initiation factor IIB chr1 GO:0003690 Not Cancer Driver No 33 0.104 80 6 0.075 0
GTF2H4 GTF2H4 Q92759 General transcription factor IIH subunit 4 chr6 GO:0003690 Not Cancer Driver No 46 0.1 30 5 0.167 0
H1F0 H1-0 P07305 Histone H1.0 chr22 GO:0003690 Not Cancer Driver No 16 0.082 194 16 0.082 0
H1FOO H1-8 Q8IZA3 Histone H1.8 chr3 GO:0003690 Not Cancer Driver No 28 0.081 322 26 0.081 0
H1FX H1-10 Q92522 Histone H1.10 chr3 GO:0003690 Not Cancer Driver No 12 0.056 198 12 0.061 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0003690 Not Cancer Driver No 46 0.124 125 19 0.152 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 GO:0003690 Not Cancer Driver No 23 0.18 71 16 0.225 0
H3F3A_ENST00000366816 H3-3B P84243 Histone H3.3 chr1 GO:0003690 Not Cancer Driver No 32 0.235 51 22 0.431 3
H3F3B_ENST00000589599 H3-3B P84243 Histone H3.3 chr17 GO:0003690 Not Cancer Driver No 28 0.206 51 14 0.275 3
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0003690 Not Cancer Driver No 47 0.217 124 29 0.234 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0003690 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDGFL1 HDGFL1 Q5TGJ6 Hepatoma-derived growth factor-like protein 1 chr6 GO:0003690 Not Cancer Driver No 48 0.191 195 24 0.123 0
HDGFL2 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 GO:0003690 Not Cancer Driver No 59 0.088 622 57 0.092 0
HDGFL3 HDGFL3 Q9Y3E1 Hepatoma-derived growth factor-related protein 3 chr15 GO:0003690 Not Cancer Driver No 25 0.123 163 18 0.11 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 GO:0003690 Not Cancer Driver No 35 0.146 203 29 0.143 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0003690 Not Cancer Driver No 37 0.132 226 32 0.142 0
HES3 HES3 Q5TGS1 Transcription factor HES-3 chr1 GO:0003690 Not Cancer Driver No 13 0.07 129 10 0.078 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0003690 Census Yes 118 0.143 435 51 0.117 0
HIST1H1A H1-1 Q02539 Histone H1.1 chr6 GO:0003690 Not Cancer Driver No 37 0.172 210 35 0.167 0
HIST1H1B H1-5 P16401 Histone H1.5 chr6 GO:0003690 Not Cancer Driver No 66 0.292 224 66 0.295 0
HIST1H1C H1-2 P16403 Histone H1.2 chr6 GO:0003690 Not Cancer Driver No 79 0.371 211 78 0.37 0
HIST1H1D H1-3 P16402 Histone H1.3 chr6 GO:0003690 Not Cancer Driver No 49 0.222 215 47 0.219 0
HIST1H1E H1-4 P10412 Histone H1.4 chr6 GO:0003690 Not Cancer Driver No 66 0.301 213 63 0.296 0
HIST1H1T H1-6 P22492 Histone H1t chr6 GO:0003690 Not Cancer Driver No 49 0.237 158 38 0.241 0
HLF HLF Q16534 Hepatic leukemia factor chr17 GO:0003690 Census Yes 56 0.19 263 51 0.194 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 GO:0003690 Not Cancer Driver No 55 0.131 319 41 0.129 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0003690 Census Yes 12 0.11 109 12 0.11 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0003690 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0003690 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMGB3 HMGB3 O15347 High mobility group protein B3 chrX GO:0003690 Not Cancer Driver No 37 0.185 182 32 0.176 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0003690 Not Cancer Driver No 77 0.093 504 45 0.089 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0003690 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSF2 HSF2 Q03933 Heat shock factor protein 2 chr6 GO:0003690 Not Cancer Driver No 64 0.119 292 37 0.127 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0003690 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFIT5 IFIT5 Q13325 Interferon-induced protein with tetratricopeptide repeats 5 chr10 GO:0003690 Not Cancer Driver No 43 0.089 19 0 0.0 0
JDP2_ENST00000435893 JDP2 Q8WYK2 Jun dimerization protein 2 chr14 GO:0003690 Not Cancer Driver No 16 0.098 142 13 0.092 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0003690 Census Yes 35 0.106 281 25 0.089 0
KIF2C KIF2C Q99661 Kinesin-like protein KIF2C chr1 GO:0003690 Not Cancer Driver No 110 0.152 337 63 0.187 0
KIN KIN O60870 DNA/RNA-binding protein KIN17 chr10 GO:0003690 Not Cancer Driver No 52 0.132 137 13 0.095 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 GO:0003690 Not Cancer Driver No 99 0.103 175 15 0.086 10
LSM14A_ENST00000433627 LSM14A Q8ND56 Protein LSM14 homolog A chr19 GO:0003690 Census Yes 67 0.145 408 63 0.154 0
MAF1_ENST00000532522 MAF1 Q9H063 Repressor of RNA polymerase III transcription MAF1 homolog chr8 GO:0003690 Not Cancer Driver No 22 0.086 74 4 0.054 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0003690 Not Cancer Driver No 128 0.169 750 126 0.168 18
MAU2 MAU2 Q9Y6X3 MAU2 chromatid cohesion factor homolog chr19 GO:0003690 Not Cancer Driver No 68 0.111 36 1 0.028 0
MAX MAX P61244 Protein max chr14 GO:0003690 Census, Compendium Yes 45 0.281 160 45 0.281 9
MBD1_ENST00000591416 MBD1 Q9UIS9 Methyl-CpG-binding domain protein 1 chr18 GO:0003690 Not Cancer Driver No 115 0.19 322 49 0.152 0
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 GO:0003690 Not Cancer Driver No 26 0.063 384 25 0.065 0
MBD4 MBD4 O95243 Methyl-CpG-binding domain protein 4 chr3 GO:0003690 Not Cancer Driver No 61 0.105 268 27 0.101 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0003690 Not Cancer Driver No 75 0.154 483 74 0.153 46
MEN1 MEN1 O00255 Menin chr11 GO:0003690 Census, Compendium Yes 73 0.119 228 15 0.066 90
MITF_ENST00000448226 MITF O75030 Microphthalmia-associated transcription factor chr3 GO:0003690 Census Yes 80 0.152 408 69 0.169 7
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0003690 Census Yes 92 0.122 208 22 0.106 85
MLH3_ENST00000556740 MLH3 Q9UHC1 DNA mismatch repair protein Mlh3 chr14 GO:0003690 Not Cancer Driver No 154 0.106 593 60 0.101 9
MLXIPL MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0003690 Not Cancer Driver No 106 0.124 554 66 0.119 0
MND1 MND1 Q9BWT6 Meiotic nuclear division protein 1 homolog chr4 GO:0003690 Not Cancer Driver No 28 0.137 85 9 0.106 0
MNDA MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 GO:0003690 Not Cancer Driver No 180 0.442 172 76 0.442 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0003690 Not Cancer Driver No 84 0.119 292 35 0.12 1
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0003690 Census Yes 92 0.099 37 4 0.108 70
MSH3 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 GO:0003690 Not Cancer Driver No 100 0.088 211 20 0.095 0
MSH4 MSH4 O15457 MutS protein homolog 4 chr1 GO:0003690 Not Cancer Driver No 199 0.213 196 42 0.214 0
MSH5_ENST00000375755 MSH5 O43196 MutS protein homolog 5 chr6 GO:0003690 Not Cancer Driver No 101 0.121 86 4 0.047 1
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0003690 Census Yes 154 0.113 386 41 0.106 6
MTERF1 MTERF1 Q99551 Transcription termination factor 1, mitochondrial chr7 GO:0003690 Not Cancer Driver No 48 0.12 0 0 0.0 0
MTERF2 MTERF2 Q49AM1 Transcription termination factor 2, mitochondrial chr12 GO:0003690 Not Cancer Driver No 49 0.127 0 0 0.0 0
MTERF4 MTERF4 Q7Z6M4 Transcription termination factor 4, mitochondrial chr2 GO:0003690 Not Cancer Driver No 47 0.123 100 11 0.11 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0003690 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUTYH MUTYH Q9UIF7 Adenine DNA glycosylase chr1 GO:0003690 Census Yes 90 0.165 198 29 0.146 23
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0003690 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0003690 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYF5 MYF5 P13349 Myogenic factor 5 chr12 GO:0003690 Not Cancer Driver No 103 0.404 122 60 0.492 1
MYF6 MYF6 P23409 Myogenic factor 6 chr12 GO:0003690 Not Cancer Driver No 89 0.368 118 44 0.373 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0003690 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0003690 Not Cancer Driver No 36 0.161 132 20 0.152 0
NCOA2 NCOA2 Q15596 Nuclear receptor coactivator 2 chr8 GO:0003690 Census, Compendium Yes 210 0.143 1281 185 0.144 0
NEIL3 NEIL3 Q8TAT5 Endonuclease 8-like 3 chr4 GO:0003690 Not Cancer Driver No 80 0.132 131 18 0.137 0
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0003690 Not Cancer Driver No 84 0.236 202 52 0.257 2
NEUROD2 NEUROD2 Q15784 Neurogenic differentiation factor 2 chr17 GO:0003690 Not Cancer Driver No 26 0.068 210 14 0.067 2
NEUROG1 NEUROG1 Q92886 Neurogenin-1 chr5 GO:0003690 Not Cancer Driver No 27 0.114 178 18 0.101 0
NEUROG2 NEUROG2 Q9H2A3 Neurogenin-2 chr4 GO:0003690 Not Cancer Driver No 32 0.118 209 29 0.139 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 GO:0003690 Census, Compendium Yes 41 0.111 334 39 0.117 7
NKX2-8 NKX2-8 O15522 Homeobox protein Nkx-2.8 chr14 GO:0003690 Not Cancer Driver No 18 0.075 162 16 0.099 0
NLRP1_ENST00000572272 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 GO:0003690 Not Cancer Driver No 222 0.151 340 65 0.191 6
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0003690 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0003690 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR2F1_ENST00000327111 NR2F1 P10589 COUP transcription factor 1 chr5 GO:0003690 Not Cancer Driver No 67 0.158 110 6 0.055 4
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0003690 Census Yes 83 0.133 298 37 0.124 0
NTHL1 NTHL1 P78549 Endonuclease III-like protein 1 chr16 GO:0003690 Census Yes 38 0.122 147 18 0.122 0
NUCKS1 NUCKS1 Q9H1E3 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 chr1 GO:0003690 Not Cancer Driver No 30 0.123 243 30 0.123 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0003690 Not Cancer Driver No 11 0.058 30 0 0.0 5
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0003690 Not Cancer Driver No 72 0.171 337 56 0.166 38
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0003690 Not Cancer Driver No 46 0.115 13 5 0.385 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0003690 Not Cancer Driver No 30 0.115 22 3 0.136 1
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0003690 Census Yes 160 0.124 948 116 0.122 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0003690 Not Cancer Driver No 30 0.103 157 13 0.083 0
PMS2 PMS2 P54278 Mismatch repair endonuclease PMS2 chr7 GO:0003690 Census, Compendium Yes 117 0.136 331 44 0.133 9
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0003690 Not Cancer Driver No 53 0.102 177 23 0.13 4
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:0003690 Not Cancer Driver No 64 0.132 46 4 0.087 3
POLR3F POLR3F Q9H1D9 DNA-directed RNA polymerase III subunit RPC6 chr20 GO:0003690 Not Cancer Driver No 20 0.063 55 5 0.091 0
POLRMT POLRMT O00411 DNA-directed RNA polymerase, mitochondrial chr19 GO:0003690 Not Cancer Driver No 188 0.153 253 31 0.123 0
POU2F1_ENST00000541643 POU2F1 P14859 POU domain, class 2, transcription factor 1 chr1 GO:0003690 Not Cancer Driver No 95 0.128 433 50 0.115 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0003690 Census Yes 72 0.143 44 4 0.091 3
PQBP1_ENST00000376563 PQBP1 O60828 Polyglutamine-binding protein 1 chrX GO:0003690 Not Cancer Driver No 42 0.158 233 38 0.163 1
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:0003690 Not Cancer Driver No 22 0.103 0 0 0.0 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0003690 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0003690 Not Cancer Driver No 83 0.13 72 6 0.083 0
PSIP1_ENST00000380738 PSIP1 O75475 PC4 and SFRS1-interacting protein chr9 GO:0003690 Census, Compendium Yes 75 0.142 481 71 0.148 0
PSMC3IP PSMC3IP Q9P2W1 Homologous-pairing protein 2 homolog chr17 GO:0003690 Not Cancer Driver No 25 0.115 73 8 0.11 0
PTF1A PTF1A Q7RTS3 Pancreas transcription factor 1 subunit alpha chr10 GO:0003690 Not Cancer Driver No 35 0.107 231 31 0.134 0
PURA PURA Q00577 Transcriptional activator protein Pur-alpha chr5 GO:0003690 Not Cancer Driver No 22 0.068 188 10 0.053 6
PURB PURB Q96QR8 Transcriptional activator protein Pur-beta chr7 GO:0003690 Not Cancer Driver No 27 0.087 161 14 0.087 0
PURG PURG Q9UJV8 Purine-rich element-binding protein gamma chr8 GO:0003690 Not Cancer Driver No 69 0.199 174 29 0.167 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 GO:0003690 Not Cancer Driver No 174 0.354 291 99 0.34 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0003690 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAD51AP1 RAD51AP1 Q96B01 RAD51-associated protein 1 chr12 GO:0003690 Not Cancer Driver No 46 0.131 335 43 0.128 0
RAD51AP2 RAD51AP2 Q09MP3 RAD51-associated protein 2 chr2 GO:0003690 Not Cancer Driver No 202 0.174 371 66 0.178 0
RAD51B_ENST00000487270 RAD51B O15315 DNA repair protein RAD51 homolog 2 chr14 GO:0003690 Census Yes 45 0.117 13 0 0.0 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0003690 Not Cancer Driver No 42 0.124 47 5 0.106 3
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0003690 Census, Compendium Yes 70 0.152 167 14 0.084 0
RBBP8_ENST00000327155 RBBP8 Q99708 DNA endonuclease RBBP8 chr18 GO:0003690 Not Cancer Driver No 99 0.11 750 76 0.101 1
RBMS1 RBMS1 P29558 RNA-binding motif, single-stranded-interacting protein 1 chr2 GO:0003690 Not Cancer Driver No 55 0.135 243 36 0.148 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0003690 Compendium Yes 75 0.136 400 48 0.12 0
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0003690 Not Cancer Driver No 142 0.129 868 113 0.13 4
REXO4 REXO4 Q9GZR2 RNA exonuclease 4 chr9 GO:0003690 Not Cancer Driver No 34 0.081 298 26 0.087 0
RFC1 RFC1 P35251 Replication factor C subunit 1 chr4 GO:0003690 Not Cancer Driver No 147 0.128 674 82 0.122 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0003690 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0003690 Not Cancer Driver No 176 0.132 241 21 0.087 0
RRN3 RRN3 Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 chr16 GO:0003690 Not Cancer Driver No 66 0.101 115 15 0.13 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0003690 Not Cancer Driver No 62 0.134 100 13 0.13 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 GO:0003690 Compendium Yes 90 0.195 184 26 0.141 0
RXRB_ENST00000374680 RXRB P28702 Retinoic acid receptor RXR-beta chr6 GO:0003690 Not Cancer Driver No 61 0.114 279 25 0.09 0
RXRG RXRG P48443 Retinoic acid receptor RXR-gamma chr1 GO:0003690 Not Cancer Driver No 103 0.222 161 41 0.255 0
SAFB_ENST00000292123 SAFB Q15424 Scaffold attachment factor B1 chr19 GO:0003690 Not Cancer Driver No 111 0.121 911 110 0.121 0
SATB1_ENST00000454909 SATB1 Q01826 DNA-binding protein SATB1 chr3 GO:0003690 Compendium Yes 130 0.17 482 84 0.174 12
SCRT2 SCRT2 Q9NQ03 Transcriptional repressor scratch 2 chr20 GO:0003690 Not Cancer Driver No 19 0.062 168 4 0.024 0
SETMAR SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0003690 Not Cancer Driver No 62 0.091 154 12 0.078 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0003690 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0003690 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0003690 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0003690 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0003690 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMC3 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 GO:0003690 Not Cancer Driver No 149 0.122 605 70 0.116 0
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0003690 Not Cancer Driver No 59 0.138 2 0 0.0 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0003690 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0003690 Not Cancer Driver No 52 0.194 52 9 0.173 0
SNAPC3_ENST00000610884 SNAPC3 Q92966 snRNA-activating protein complex subunit 3 chr9 GO:0003690 Not Cancer Driver No 30 0.073 99 2 0.02 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 GO:0003690 Not Cancer Driver No 96 0.122 599 71 0.119 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 GO:0003690 Not Cancer Driver No 73 0.149 252 38 0.151 1
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0003690 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0003690 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRF SRF P11831 Serum response factor chr6 GO:0003690 Not Cancer Driver No 44 0.087 443 42 0.095 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0003690 Not Cancer Driver No 131 0.175 144 25 0.174 26
SYCP1_ENST00000618516 SYCP1 Q15431 Synaptonemal complex protein 1 chr1 GO:0003690 Not Cancer Driver No 207 0.212 602 124 0.206 0
TAF1B TAF1B Q53T94 TATA box-binding protein-associated factor RNA polymerase I subunit B chr2 GO:0003690 Not Cancer Driver No 61 0.104 54 7 0.13 0
TAF1C TAF1C Q15572 TATA box-binding protein-associated factor RNA polymerase I subunit C chr16 GO:0003690 Not Cancer Driver No 114 0.131 312 35 0.112 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0003690 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0003690 Census Yes 54 0.163 305 53 0.174 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:0003690 Not Cancer Driver No 51 0.123 202 15 0.074 27
TBP TBP P20226 TATA-box-binding protein chr6 GO:0003690 Not Cancer Driver No 40 0.118 164 14 0.085 0
TBPL1 TBPL1 P62380 TATA box-binding protein-like 1 chr6 GO:0003690 Not Cancer Driver No 27 0.145 6 0 0.0 0
TCF12_ENST00000267811 TCF12 Q99081 Transcription factor 12 chr15 GO:0003690 Census Yes 105 0.154 680 105 0.154 3
TCF15 TCF15 Q12870 Transcription factor 15 chr20 GO:0003690 Not Cancer Driver No 19 0.095 134 4 0.03 0
TCF21 TCF21 O43680 Transcription factor 21 chr6 GO:0003690 Not Cancer Driver No 55 0.307 120 40 0.333 0
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 GO:0003690 Census Yes 52 0.08 649 52 0.08 0
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 GO:0003690 Compendium Yes 141 0.211 662 136 0.205 13
TDG TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0003690 Not Cancer Driver No 75 0.183 185 31 0.168 0
TDP1_ENST00000393454 TDP1 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 chr14 GO:0003690 Not Cancer Driver No 81 0.133 179 25 0.14 1
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:0003690 Not Cancer Driver No 63 0.144 220 34 0.155 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0003690 Not Cancer Driver No 33 0.061 361 20 0.055 0
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 GO:0003690 Not Cancer Driver No 25 0.102 110 15 0.136 1
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0003690 Compendium Yes 61 0.18 285 52 0.182 0
TOP1 TOP1 P11387 DNA topoisomerase 1 chr20 GO:0003690 Census, Compendium Yes 93 0.122 391 53 0.136 0
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0003690 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 GO:0003690 Census, Compendium Yes 120 0.114 537 61 0.114 0
TSPYL2 TSPYL2 Q9H2G4 Testis-specific Y-encoded-like protein 2 chrX GO:0003690 Not Cancer Driver No 80 0.115 509 55 0.108 0
TSTD1 TSTD1 Q8NFU3 Thiosulfate:glutathione sulfurtransferase chr1 GO:0003690 Not Cancer Driver No 4 0.035 4 0 0.0 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0003690 Not Cancer Driver No 23 0.114 132 11 0.083 7
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 GO:0003690 Not Cancer Driver No 100 0.131 567 77 0.136 1
UHRF1_ENST00000616255 UHRF1 Q96T88 E3 ubiquitin-protein ligase UHRF1 chr19 GO:0003690 Not Cancer Driver No 97 0.122 353 49 0.139 0
VAX1 VAX1 Q5SQQ9 Ventral anterior homeobox 1 chr10 GO:0003690 Not Cancer Driver No 36 0.108 234 25 0.107 1
VAX2 VAX2 Q9UIW0 Ventral anterior homeobox 2 chr2 GO:0003690 Not Cancer Driver No 34 0.117 210 22 0.105 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0003690 Not Cancer Driver No 64 0.15 102 16 0.157 14
WDR48 WDR48 Q8TAF3 WD repeat-containing protein 48 chr3 GO:0003690 Not Cancer Driver No 61 0.09 125 19 0.152 0
XPC XPC Q01831 DNA repair protein complementing XP-C cells chr3 GO:0003690 Census, Compendium Yes 88 0.094 479 48 0.1 2
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0003690 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0003690 Not Cancer Driver No 66 0.108 140 12 0.086 0
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 GO:0003690 Not Cancer Driver No 129 0.136 427 63 0.148 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0003690 Not Cancer Driver No 41 0.127 312 41 0.131 0
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 GO:0003690 Not Cancer Driver No 97 0.226 385 80 0.208 0
ZBTB48 ZBTB48 P10074 Telomere zinc finger-associated protein chr1 GO:0003690 Not Cancer Driver No 53 0.077 237 16 0.068 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0003690 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:0003690 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0003690 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0003690 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZMYND11 ZMYND11 Q15326 Zinc finger MYND domain-containing protein 11 chr10 GO:0003690 Not Cancer Driver No 71 0.118 184 26 0.141 0
ZNF350 ZNF350 Q9GZX5 Zinc finger protein 350 chr19 GO:0003690 Not Cancer Driver No 86 0.162 95 18 0.189 0
ZNF445_ENST00000425708 ZNF445 P59923 Zinc finger protein 445 chr3 GO:0003690 Not Cancer Driver No 136 0.132 398 61 0.153 0
ZNF536 ZNF536 O15090 Zinc finger protein 536 chr19 GO:0003690 Not Cancer Driver No 596 0.458 991 445 0.449 0
ZNF638 ZNF638 Q14966 Zinc finger protein 638 chr2 GO:0003690 Not Cancer Driver No 243 0.123 1667 209 0.125 0
ZW10 ZW10 O43264 Centromere/kinetochore protein zw10 homolog chr11 GO:0003690 Not Cancer Driver No 90 0.116 63 11 0.175 0