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Total number of protein in "GO:0002831" GO term:  276

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A2M A2M P01023 Alpha-2-macroglobulin chr12 GO:0002831 Not Cancer Driver No 260 0.176 144 22 0.153 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0002831 Not Cancer Driver No 5 0.01 36 0 0.0 0
ADAR ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0002831 Not Cancer Driver No 149 0.122 675 83 0.123 12
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0002831 Not Cancer Driver No 129 0.152 351 75 0.214 0
AIM2 AIM2 O14862 Interferon-inducible protein AIM2 chr1 GO:0002831 Not Cancer Driver No 73 0.213 78 22 0.282 0
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 GO:0002831 Not Cancer Driver No 312 0.12 1790 221 0.123 9
AP1G1_ENST00000569748 AP1G1 O43747 AP-1 complex subunit gamma-1 chr16 GO:0002831 Not Cancer Driver No 111 0.135 144 22 0.153 0
APOBEC3F APOBEC3F Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F chr22 GO:0002831 Not Cancer Driver No 49 0.131 0 0 0.0 0
APOBEC3G APOBEC3G Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G chr22 GO:0002831 Not Cancer Driver No 61 0.159 0 0 0.0 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0002831 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0002831 Not Cancer Driver No 25 0.071 58 3 0.052 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0002831 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATG12 ATG12 O94817 Ubiquitin-like protein ATG12 chr5 GO:0002831 Not Cancer Driver No 15 0.107 60 8 0.133 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 GO:0002831 Not Cancer Driver No 40 0.145 25 6 0.24 1
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 GO:0002831 Not Cancer Driver No 10 0.112 11 2 0.182 1
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0002831 Not Cancer Driver No 69 0.112 83 9 0.108 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 GO:0002831 Census, Compendium Yes 77 0.127 98 16 0.163 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0002831 Not Cancer Driver No 95 0.185 226 51 0.226 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0002831 Not Cancer Driver No 14 0.05 103 6 0.058 2
C6orf106 ILRUN Q9H6K1 Protein ILRUN chr6 GO:0002831 Not Cancer Driver No 23 0.077 113 6 0.053 0
CACTIN CACTIN Q8WUQ7 Cactin chr19 GO:0002831 Not Cancer Driver No 94 0.124 503 54 0.107 0
CADM1_ENST00000452722 CADM1 Q9BY67 Cell adhesion molecule 1 chr11 GO:0002831 Not Cancer Driver No 106 0.24 103 28 0.272 0
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0002831 Not Cancer Driver No 18 0.121 115 13 0.113 8
CARD16 CARD16 Q5EG05 Caspase recruitment domain-containing protein 16 chr11 GO:0002831 Not Cancer Driver No 36 0.183 23 7 0.304 0
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0002831 Not Cancer Driver No 53 0.099 126 7 0.056 1
CCDC92 CCDC92 Q53HC0 Coiled-coil domain-containing protein 92 chr12 GO:0002831 Not Cancer Driver No 60 0.181 299 49 0.164 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0002831 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD180 CD180 Q99467 CD180 antigen chr5 GO:0002831 Not Cancer Driver No 105 0.159 0 0 0.0 0
CD226_ENST00000582621 CD226 Q15762 CD226 antigen chr18 GO:0002831 Not Cancer Driver No 79 0.235 47 11 0.234 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0002831 Census Yes 29 0.1 54 9 0.167 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0002831 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0002831 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD96 CD96 P40200 T-cell surface protein tactile chr3 GO:0002831 Not Cancer Driver No 132 0.226 165 34 0.206 1
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 GO:0002831 Not Cancer Driver No 52 0.138 214 31 0.145 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0002831 Not Cancer Driver No 64 0.122 241 25 0.104 0
CFH CFH P08603 Complement factor H chr1 GO:0002831 Not Cancer Driver No 355 0.288 89 28 0.315 42
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0002831 Not Cancer Driver No 50 0.096 173 7 0.04 0
CLEC12B CLEC12B Q2HXU8 C-type lectin domain family 12 member B chr12 GO:0002831 Not Cancer Driver No 34 0.123 57 8 0.14 0
CLEC6A CLEC6A Q6EIG7 C-type lectin domain family 6 member A chr12 GO:0002831 Not Cancer Driver No 41 0.196 7 0 0.0 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0002831 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLNK CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0002831 Not Cancer Driver No 85 0.199 320 73 0.228 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0002831 Not Cancer Driver No 31 0.109 21 1 0.048 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0002831 Compendium Yes 383 0.188 151 42 0.278 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 GO:0002831 Census, Compendium Yes 412 0.169 1796 247 0.138 33
CRK CRK P46108 Adapter molecule crk chr17 GO:0002831 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0002831 Not Cancer Driver No 64 0.163 135 14 0.104 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0002831 Not Cancer Driver No 66 0.166 259 44 0.17 0
CXCL6 CXCL6 P80162 C-X-C motif chemokine 6 chr4 GO:0002831 Not Cancer Driver No 17 0.149 9 1 0.111 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0002831 Not Cancer Driver No 26 0.133 66 2 0.03 12
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:0002831 Not Cancer Driver No 193 0.135 114 11 0.096 0
DCST1 DCST1 Q5T197 E3 ubiquitin-protein ligase DCST1 chr1 GO:0002831 Not Cancer Driver No 108 0.153 51 9 0.176 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0002831 Not Cancer Driver No 118 0.128 61 10 0.164 2
DDX60 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 GO:0002831 Not Cancer Driver No 224 0.131 131 12 0.092 0
DEFB114 DEFB114 Q30KQ6 Beta-defensin 114 chr6 GO:0002831 Not Cancer Driver No 31 0.449 0 0 0.0 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:0002831 Not Cancer Driver No 62 0.091 84 8 0.095 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0002831 Compendium Yes 182 0.143 331 42 0.127 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0002831 Not Cancer Driver No 127 0.287 124 45 0.363 0
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0002831 Not Cancer Driver No 86 0.116 260 24 0.092 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0002831 Not Cancer Driver No 81 0.168 135 24 0.178 0
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0002831 Not Cancer Driver No 156 0.095 494 44 0.089 2
ELMOD2 ELMOD2 Q8IZ81 ELMO domain-containing protein 2 chr4 GO:0002831 Not Cancer Driver No 29 0.099 0 0 0.0 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 GO:0002831 Not Cancer Driver No 125 0.123 669 69 0.103 0
EMILIN2 EMILIN2 Q9BXX0 EMILIN-2 chr18 GO:0002831 Not Cancer Driver No 158 0.15 617 94 0.152 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0002831 Census, Compendium Yes 334 0.138 1790 196 0.109 1
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0002831 Not Cancer Driver No 55 0.139 7 2 0.286 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0002831 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM3A_ENST00000447601 FAM3A P98173 Protein FAM3A chrX GO:0002831 Not Cancer Driver No 27 0.117 48 9 0.188 0
FBXO38_ENST00000340253 FBXO38 Q6PIJ6 F-box only protein 38 chr5 GO:0002831 Not Cancer Driver No 133 0.112 440 48 0.109 1
FCN1 FCN1 O00602 Ficolin-1 chr9 GO:0002831 Not Cancer Driver No 107 0.328 88 15 0.17 0
FFAR2 FFAR2 O15552 Free fatty acid receptor 2 chr19 GO:0002831 Not Cancer Driver No 49 0.148 32 7 0.219 0
FGL2 FGL2 Q14314 Fibroleukin chr7 GO:0002831 Not Cancer Driver No 71 0.162 70 12 0.171 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0002831 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0002831 Not Cancer Driver No 38 0.088 186 16 0.086 10
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0002831 Not Cancer Driver No 92 0.171 70 13 0.186 0
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0002831 Not Cancer Driver No 57 0.096 476 51 0.107 10
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0002831 Not Cancer Driver No 10 0.049 97 4 0.041 1
GPATCH3 GPATCH3 Q96I76 G patch domain-containing protein 3 chr1 GO:0002831 Not Cancer Driver No 64 0.122 354 48 0.136 0
GRN GRN P28799 Progranulin chr17 GO:0002831 Not Cancer Driver No 76 0.128 29 6 0.207 1
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0002831 Not Cancer Driver No 69 0.229 17 2 0.118 3
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0002831 Not Cancer Driver No 112 0.213 124 25 0.202 0
HERC5 HERC5 Q9UII4 E3 ISG15--protein ligase HERC5 chr4 GO:0002831 Not Cancer Driver No 124 0.121 118 12 0.102 0
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0002831 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:0002831 Compendium Yes 78 0.215 169 34 0.201 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0002831 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0002831 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:0002831 Not Cancer Driver No 43 0.124 115 22 0.191 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0002831 Not Cancer Driver No 94 0.278 85 22 0.259 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0002831 Not Cancer Driver No 25 0.116 203 20 0.099 0
HPX HPX P02790 Hemopexin chr11 GO:0002831 Not Cancer Driver No 60 0.13 53 8 0.151 0
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0002831 Not Cancer Driver No 121 0.23 277 75 0.271 2
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0002831 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0002831 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0002831 Not Cancer Driver No 61 0.106 82 6 0.073 2
HTRA1 HTRA1 Q92743 Serine protease HTRA1 chr10 GO:0002831 Not Cancer Driver No 77 0.16 40 9 0.225 11
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0002831 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFIT1 IFIT1 P09914 Interferon-induced protein with tetratricopeptide repeats 1 chr10 GO:0002831 Not Cancer Driver No 49 0.103 52 3 0.058 0
IFIT1B IFIT1B Q5T764 Interferon-induced protein with tetratricopeptide repeats 1B chr10 GO:0002831 Not Cancer Driver No 59 0.124 21 1 0.048 0
IFNLR1 IFNLR1 Q8IU57 Interferon lambda receptor 1 chr1 GO:0002831 Not Cancer Driver No 57 0.11 256 33 0.129 0
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0002831 Census, Compendium Yes 106 0.14 211 31 0.147 1
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 GO:0002831 Not Cancer Driver No 108 0.151 76 13 0.171 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0002831 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0002831 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0002831 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:0002831 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL17F IL17F Q96PD4 Interleukin-17F chr6 GO:0002831 Not Cancer Driver No 42 0.258 34 11 0.324 1
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0002831 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0002831 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0002831 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL27 IL27 Q8NEV9 Interleukin-27 subunit alpha chr16 GO:0002831 Not Cancer Driver No 37 0.152 27 1 0.037 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0002831 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0002831 Not Cancer Driver No 65 0.115 136 14 0.103 0
INS INS P01308 Insulin chr11 GO:0002831 Not Cancer Driver No 15 0.136 5 1 0.2 22
IRAK3 IRAK3 Q9Y616 Interleukin-1 receptor-associated kinase 3 chr12 GO:0002831 Not Cancer Driver No 103 0.173 79 14 0.177 0
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0002831 Not Cancer Driver No 36 0.084 204 21 0.103 1
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0002831 Not Cancer Driver No 43 0.085 253 19 0.075 1
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0002831 Not Cancer Driver No 9 0.05 45 1 0.022 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 GO:0002831 Not Cancer Driver No 12 0.073 24 2 0.083 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0002831 Not Cancer Driver No 95 0.105 335 42 0.125 0
KLK3 KLK3 P07288 Prostate-specific antigen chr19 GO:0002831 Not Cancer Driver No 68 0.261 6 1 0.167 0
KLK5_ENST00000593428 KLK5 Q9Y337 Kallikrein-5 chr19 GO:0002831 Not Cancer Driver No 69 0.235 75 16 0.213 0
KLK7 KLK7 P49862 Kallikrein-7 chr19 GO:0002831 Not Cancer Driver No 43 0.17 38 8 0.211 0
KLRC1 KLRC1 P26715 NKG2-A/NKG2-B type II integral membrane protein chr12 GO:0002831 Not Cancer Driver No 49 0.21 49 10 0.204 0
KLRC2 KLRC2 P26717 NKG2-C type II integral membrane protein chr12 GO:0002831 Not Cancer Driver No 55 0.238 45 17 0.378 0
KLRC3_ENST00000396439 KLRC3 Q07444 NKG2-E type II integral membrane protein chr12 GO:0002831 Not Cancer Driver No 37 0.154 43 4 0.093 0
KLRC4 KLRC4 O43908 NKG2-F type II integral membrane protein chr12 GO:0002831 Not Cancer Driver No 36 0.228 45 7 0.156 0
KLRD1 KLRD1 Q13241 Natural killer cells antigen CD94 chr12 GO:0002831 Not Cancer Driver No 37 0.207 0 0 0.0 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0002831 Not Cancer Driver No 38 0.176 0 0 0.0 0
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:0002831 Not Cancer Driver No 38 0.275 90 27 0.3 0
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 GO:0002831 Not Cancer Driver No 47 0.113 93 10 0.108 0
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0002831 Not Cancer Driver No 84 0.175 6 0 0.0 0
LEP LEP P41159 Leptin chr7 GO:0002831 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0002831 Not Cancer Driver No 54 0.152 65 16 0.246 0
LILRA2 LILRA2 Q8N149 Leukocyte immunoglobulin-like receptor subfamily A member 2 chr19 GO:0002831 Not Cancer Driver No 163 0.337 137 44 0.321 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0002831 Not Cancer Driver No 203 0.312 291 97 0.333 0
LRSAM1_ENST00000373322 LRSAM1 Q6UWE0 E3 ubiquitin-protein ligase LRSAM1 chr9 GO:0002831 Not Cancer Driver No 86 0.119 240 30 0.125 1
LSM14A_ENST00000433627 LSM14A Q8ND56 Protein LSM14 homolog A chr19 GO:0002831 Census Yes 67 0.145 408 63 0.154 0
LTF LTF P02788 Lactotransferrin chr3 GO:0002831 Not Cancer Driver No 131 0.185 21 4 0.19 0
LY86 LY86 O95711 Lymphocyte antigen 86 chr6 GO:0002831 Not Cancer Driver No 29 0.179 0 0 0.0 0
LY96 LY96 Q9Y6Y9 Lymphocyte antigen 96 chr8 GO:0002831 Not Cancer Driver No 37 0.231 0 0 0.0 0
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 GO:0002831 Not Cancer Driver No 50 0.132 249 31 0.124 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0002831 Census Yes 95 0.186 84 12 0.143 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0002831 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0002831 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPKBP1 MAPKBP1 O60336 Mitogen-activated protein kinase-binding protein 1 chr15 GO:0002831 Not Cancer Driver No 166 0.11 786 67 0.085 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0002831 Not Cancer Driver No 70 0.13 411 58 0.141 0
MBL2 MBL2 P11226 Mannose-binding protein C chr10 GO:0002831 Not Cancer Driver No 63 0.254 122 32 0.262 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0002831 Not Cancer Driver No 162 0.102 1104 117 0.106 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0002831 Not Cancer Driver No 74 0.128 274 29 0.106 0
MICB MICB Q29980 MHC class I polypeptide-related sequence B chr6 GO:0002831 Not Cancer Driver No 56 0.146 175 22 0.126 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0002831 Not Cancer Driver No 4 0.035 0 0 0.0 0
MMP12 MMP12 P39900 Macrophage metalloelastase chr11 GO:0002831 Not Cancer Driver No 100 0.213 29 5 0.172 0
MR1 MR1 Q95460 Major histocompatibility complex class I-related gene protein chr1 GO:0002831 Not Cancer Driver No 60 0.176 33 7 0.212 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0002831 Not Cancer Driver No 48 0.136 16 2 0.125 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0002831 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCR1 NCR1 O76036 Natural cytotoxicity triggering receptor 1 chr19 GO:0002831 Not Cancer Driver No 81 0.266 27 8 0.296 0
NECTIN2 NECTIN2 Q92692 Nectin-2 chr19 GO:0002831 Not Cancer Driver No 63 0.117 296 29 0.098 0
NFKBIL1 NFKBIL1 Q9UBC1 NF-kappa-B inhibitor-like protein 1 chr6 GO:0002831 Not Cancer Driver No 37 0.097 316 33 0.104 0
NLRC3 NLRC3 Q7RTR2 NLR family CARD domain-containing protein 3 chr16 GO:0002831 Not Cancer Driver No 176 0.165 147 33 0.224 0
NLRC5_ENST00000436936 NLRC5 Q86WI3 Protein NLRC5 chr16 GO:0002831 Not Cancer Driver No 262 0.14 114 19 0.167 0
NLRP10 NLRP10 Q86W26 NACHT, LRR and PYD domains-containing protein 10 chr11 GO:0002831 Not Cancer Driver No 201 0.307 96 34 0.354 0
NLRX1_ENST00000409265 NLRX1 Q86UT6 NLR family member X1 chr11 GO:0002831 Not Cancer Driver No 158 0.162 94 13 0.138 0
NMI NMI Q13287 N-myc-interactor chr2 GO:0002831 Not Cancer Driver No 34 0.111 104 12 0.115 0
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0002831 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0002831 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:0002831 Not Cancer Driver No 59 0.123 391 41 0.105 0
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 GO:0002831 Not Cancer Driver No 78 0.128 47 8 0.17 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0002831 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0002831 Not Cancer Driver No 56 0.125 146 13 0.089 0
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0002831 Not Cancer Driver No 67 0.168 71 12 0.169 0
OAS3 OAS3 Q9Y6K5 2'-5'-oligoadenylate synthase 3 chr12 GO:0002831 Not Cancer Driver No 139 0.128 147 17 0.116 0
OASL OASL Q15646 2'-5'-oligoadenylate synthase-like protein chr12 GO:0002831 Not Cancer Driver No 76 0.148 8 4 0.5 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 GO:0002831 Not Cancer Driver No 58 0.101 470 51 0.109 6
OTOP1 OTOP1 Q7RTM1 Proton channel OTOP1 chr4 GO:0002831 Not Cancer Driver No 104 0.17 89 11 0.124 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0002831 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0002831 Compendium Yes 89 0.17 242 49 0.202 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0002831 Not Cancer Driver No 127 0.227 286 64 0.224 2
PARP14 PARP14 Q460N5 Protein mono-ADP-ribosyltransferase PARP14 chr3 GO:0002831 Not Cancer Driver No 221 0.123 301 57 0.189 0
PARP9 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 GO:0002831 Not Cancer Driver No 110 0.129 45 3 0.067 0
PCBP2_ENST00000439930 PCBP2 Q15366 Poly(rC)-binding protein 2 chr12 GO:0002831 Not Cancer Driver No 40 0.11 200 24 0.12 0
PGC PGC P20142 Gastricsin chr6 GO:0002831 Not Cancer Driver No 60 0.155 20 1 0.05 0
PIK3R6_ENST00000614407 PIK3R6 Q5UE93 Phosphoinositide 3-kinase regulatory subunit 6 chr17 GO:0002831 Not Cancer Driver No 100 0.133 156 26 0.167 0
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0002831 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0002831 Not Cancer Driver No 248 0.196 142 30 0.211 1
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0002831 Census Yes 72 0.143 44 4 0.091 3
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 GO:0002831 Not Cancer Driver No 65 0.136 243 31 0.128 0
PPP2R3C PPP2R3C Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma chr14 GO:0002831 Not Cancer Driver No 44 0.097 30 3 0.1 0
PQBP1_ENST00000376563 PQBP1 O60828 Polyglutamine-binding protein 1 chrX GO:0002831 Not Cancer Driver No 42 0.158 233 38 0.163 1
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0002831 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0002831 Not Cancer Driver No 94 0.14 154 22 0.143 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0002831 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0002831 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0002831 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0002831 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0002831 Census, Compendium Yes 73 0.123 192 25 0.13 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 GO:0002831 Not Cancer Driver No 150 0.126 640 77 0.12 3
PUM2_ENST00000403432 PUM2 Q8TB72 Pumilio homolog 2 chr2 GO:0002831 Not Cancer Driver No 132 0.124 575 83 0.144 0
PVR PVR P15151 Poliovirus receptor chr19 GO:0002831 Not Cancer Driver No 39 0.094 120 19 0.158 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0002831 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAET1G RAET1G Q6H3X3 UL-16 binding protein 5 chr6 GO:0002831 Not Cancer Driver No 41 0.123 62 10 0.161 0
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0002831 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0002831 Not Cancer Driver No 63 0.117 143 20 0.14 0
RNF125 RNF125 Q96EQ8 E3 ubiquitin-protein ligase RNF125 chr18 GO:0002831 Not Cancer Driver No 35 0.151 26 1 0.038 3
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0002831 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF216_ENST00000425013 RNF216 Q9NWF9 E3 ubiquitin-protein ligase RNF216 chr7 GO:0002831 Not Cancer Driver No 108 0.125 415 57 0.137 2
RNF26 RNF26 Q9BY78 E3 ubiquitin-protein ligase RNF26 chr11 GO:0002831 Not Cancer Driver No 44 0.102 71 7 0.099 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 GO:0002831 Not Cancer Driver No 142 0.132 319 45 0.141 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 GO:0002831 Not Cancer Driver No 15 0.103 61 3 0.049 23
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 GO:0002831 Not Cancer Driver No 104 0.166 91 14 0.154 13
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0002831 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SCIMP SCIMP Q6UWF3 SLP adapter and CSK-interacting membrane protein chr17 GO:0002831 Not Cancer Driver No 10 0.069 73 9 0.123 0
SEC14L1_ENST00000436233 SEC14L1 Q92503 SEC14-like protein 1 chr17 GO:0002831 Not Cancer Driver No 104 0.145 82 16 0.195 0
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0002831 Not Cancer Driver No 10 0.106 47 6 0.128 0
SERPINB4 SERPINB4 P48594 Serpin B4 chr18 GO:0002831 Not Cancer Driver No 120 0.308 48 18 0.375 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 GO:0002831 Not Cancer Driver No 64 0.17 22 2 0.091 0
SERPING1 SERPING1 P05155 Plasma protease C1 inhibitor chr11 GO:0002831 Not Cancer Driver No 74 0.148 113 13 0.115 40
SH2D1B SH2D1B O14796 SH2 domain-containing protein 1B chr1 GO:0002831 Not Cancer Driver No 34 0.258 0 0 0.0 0
SIGIRR_ENST00000397632 SIGIRR Q6IA17 Single Ig IL-1-related receptor chr11 GO:0002831 Not Cancer Driver No 27 0.066 85 4 0.047 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0002831 Compendium Yes 172 0.135 617 73 0.118 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0002831 Not Cancer Driver No 56 0.144 85 17 0.2 0
SLAMF8 SLAMF8 Q9P0V8 SLAM family member 8 chr1 GO:0002831 Not Cancer Driver No 63 0.221 20 2 0.1 0
SLC22A13 SLC22A13 Q9Y226 Solute carrier family 22 member 13 chr3 GO:0002831 Not Cancer Driver No 55 0.1 32 3 0.094 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0002831 Census, Compendium Yes 22 0.104 66 3 0.045 2
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0002831 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPINK5_ENST00000256084 SPINK5 Q9NQ38 Serine protease inhibitor Kazal-type 5 chr5 GO:0002831 Not Cancer Driver No 168 0.158 590 102 0.173 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0002831 Census Yes 53 0.099 130 11 0.085 1
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0002831 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT2 STAT2 P52630 Signal transducer and activator of transcription 2 chr12 GO:0002831 Not Cancer Driver No 90 0.106 178 22 0.124 2
SUSD4 SUSD4 Q5VX71 Sushi domain-containing protein 4 chr1 GO:0002831 Not Cancer Driver No 85 0.173 134 27 0.201 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0002831 Census Yes 96 0.151 131 27 0.206 5
SYT11 SYT11 Q9BT88 Synaptotagmin-11 chr1 GO:0002831 Not Cancer Driver No 64 0.148 105 23 0.219 0
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 GO:0002831 Not Cancer Driver No 45 0.123 203 22 0.108 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0002831 Not Cancer Driver No 101 0.139 42 5 0.119 12
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0002831 Not Cancer Driver No 44 0.163 39 9 0.231 0
TKFC TKFC Q3LXA3 Triokinase/FMN cyclase chr11 GO:0002831 Not Cancer Driver No 66 0.115 91 14 0.154 2
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0002831 Not Cancer Driver No 46 0.121 66 13 0.197 3
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0002831 Census, Compendium Yes 98 0.124 231 33 0.143 1
TOMM70 TOMM70 O94826 Mitochondrial import receptor subunit TOM70 chr3 GO:0002831 Not Cancer Driver No 59 0.097 140 8 0.057 0
TRAF3IP1 TRAF3IP1 Q8TDR0 TRAF3-interacting protein 1 chr2 GO:0002831 Not Cancer Driver No 75 0.109 507 60 0.118 4
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 GO:0002831 Not Cancer Driver No 59 0.103 410 39 0.095 2
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 GO:0002831 Compendium Yes 61 0.107 101 9 0.089 1
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0002831 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAFD1_ENST00000412615 TRAFD1 O14545 TRAF-type zinc finger domain-containing protein 1 chr12 GO:0002831 Not Cancer Driver No 55 0.095 374 32 0.086 0
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0002831 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0002831 Not Cancer Driver No 47 0.126 91 5 0.055 0
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 GO:0002831 Not Cancer Driver No 69 0.148 79 11 0.139 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 GO:0002831 Not Cancer Driver No 85 0.179 49 7 0.143 0
TRIM38 TRIM38 O00635 E3 ubiquitin-protein ligase TRIM38 chr6 GO:0002831 Not Cancer Driver No 62 0.133 47 8 0.17 0
TRIM41 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 GO:0002831 Not Cancer Driver No 69 0.11 385 38 0.099 0
TRIM44 TRIM44 Q96DX7 Tripartite motif-containing protein 44 chr11 GO:0002831 Not Cancer Driver No 40 0.116 272 33 0.121 1
TRIM5 TRIM5 Q9C035 Tripartite motif-containing protein 5 chr11 GO:0002831 Not Cancer Driver No 71 0.144 77 11 0.143 0
TRIM56 TRIM56 Q9BRZ2 E3 ubiquitin-protein ligase TRIM56 chr7 GO:0002831 Not Cancer Driver No 110 0.146 217 36 0.166 0
TRIM62 TRIM62 Q9BVG3 E3 ubiquitin-protein ligase TRIM62 chr1 GO:0002831 Not Cancer Driver No 58 0.122 80 14 0.175 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0002831 Not Cancer Driver No 86 0.176 47 15 0.319 0
TSPAN32 TSPAN32 Q96QS1 Tetraspanin-32 chr11 GO:0002831 Not Cancer Driver No 33 0.103 8 3 0.375 0
TSPAN6 TSPAN6 O43657 Tetraspanin-6 chrX GO:0002831 Not Cancer Driver No 34 0.139 0 0 0.0 0
TTLL12 TTLL12 Q14166 Tubulin--tyrosine ligase-like protein 12 chr22 GO:0002831 Not Cancer Driver No 69 0.107 100 6 0.06 0
TXK TXK P42681 Tyrosine-protein kinase TXK chr4 GO:0002831 Not Cancer Driver No 87 0.165 61 9 0.148 0
TYRO3 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0002831 Not Cancer Driver No 119 0.134 197 17 0.086 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0002831 Not Cancer Driver No 24 0.212 28 8 0.286 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0002831 Not Cancer Driver No 24 0.12 33 3 0.091 0
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 GO:0002831 Not Cancer Driver No 26 0.085 100 7 0.07 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:0002831 Not Cancer Driver No 136 0.139 259 39 0.151 0
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:0002831 Not Cancer Driver No 105 0.198 201 54 0.269 0
USP18 USP18 Q9UMW8 Ubl carboxyl-terminal hydrolase 18 chr22 GO:0002831 Not Cancer Driver No 34 0.091 29 8 0.276 0
USP27X USP27X A6NNY8 Ubiquitin carboxyl-terminal hydrolase 27 chrX GO:0002831 Not Cancer Driver No 31 0.071 69 3 0.043 1
USP29_ENST00000598197 USP29 Q9HBJ7 Ubiquitin carboxyl-terminal hydrolase 29 chr19 GO:0002831 Not Cancer Driver No 291 0.316 432 132 0.306 0
VSIG4 VSIG4 Q9Y279 V-set and immunoglobulin domain-containing protein 4 chrX GO:0002831 Not Cancer Driver No 73 0.183 70 13 0.186 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0002831 Not Cancer Driver No 66 0.174 0 0 0.0 2
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0002831 Not Cancer Driver No 67 0.116 376 44 0.117 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 GO:0002831 Not Cancer Driver No 74 0.126 409 51 0.125 0
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 GO:0002831 Not Cancer Driver No 97 0.226 385 80 0.208 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0002831 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:0002831 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZDHHC1 ZDHHC1 Q8WTX9 Palmitoyltransferase ZDHHC1 chr16 GO:0002831 Not Cancer Driver No 46 0.095 167 11 0.066 0
ZDHHC11 ZDHHC11 Q9H8X9 Palmitoyltransferase ZDHHC11 chr5 GO:0002831 Not Cancer Driver No 68 0.165 76 24 0.316 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0002831 Not Cancer Driver No 67 0.141 23 0 0.0 3