Filter in search result
Please select a valid state.

Total number of protein in "GO:0001934" GO term:  512

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 GO:0001934 Census, Compendium Yes 55 0.108 360 39 0.108 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0001934 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0001934 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0001934 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0001934 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0001934 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0001934 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0001934 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0001934 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0001934 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0001934 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0001934 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRA2B ADRA2B P18089 Alpha-2B adrenergic receptor chr2 GO:0001934 Not Cancer Driver No 73 0.162 136 20 0.147 0
ADRA2C ADRA2C P18825 Alpha-2C adrenergic receptor chr4 GO:0001934 Not Cancer Driver No 47 0.102 107 0 0.0 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0001934 Not Cancer Driver No 52 0.126 35 4 0.114 0
ADTRP_ENST00000414691 ADTRP Q96IZ2 Androgen-dependent TFPI-regulating protein chr6 GO:0001934 Not Cancer Driver No 41 0.178 2 0 0.0 0
AFAP1L2 AFAP1L2 Q8N4X5 Actin filament-associated protein 1-like 2 chr10 GO:0001934 Not Cancer Driver No 86 0.105 558 59 0.106 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0001934 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGT AGT P01019 Angiotensinogen chr1 GO:0001934 Not Cancer Driver No 85 0.179 33 10 0.303 1
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0001934 Not Cancer Driver No 14 0.095 61 6 0.098 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0001934 Census Yes 474 0.121 2281 268 0.117 1
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0001934 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0001934 Census Yes 77 0.16 84 9 0.107 2
AKTIP_ENST00000570004 AKTIP Q9H8T0 AKT-interacting protein chr16 GO:0001934 Not Cancer Driver No 33 0.113 95 10 0.105 0
ALKAL1 ALKAL1 Q6UXT8 ALK and LTK ligand 1 chr8 GO:0001934 Not Cancer Driver No 18 0.14 49 3 0.061 0
ALKAL2 ALKAL2 Q6UX46 ALK and LTK ligand 2 chr2 GO:0001934 Not Cancer Driver No 7 0.046 31 0 0.0 0
ANG ANG P03950 Angiogenin chr14 GO:0001934 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0001934 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANGPT4 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0001934 Not Cancer Driver No 104 0.207 150 32 0.213 0
APLNR APLNR P35414 Apelin receptor chr11 GO:0001934 Not Cancer Driver No 96 0.253 29 8 0.276 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0001934 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX GO:0001934 Census, Compendium Yes 84 0.139 181 32 0.177 0
AREG AREG P15514 Amphiregulin chr4 GO:0001934 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0001934 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 GO:0001934 Not Cancer Driver No 49 0.117 154 13 0.084 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0001934 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0001934 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATG14 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 GO:0001934 Not Cancer Driver No 48 0.098 209 24 0.115 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0001934 Census, Compendium Yes 469 0.153 225 39 0.173 41
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0001934 Not Cancer Driver No 14 0.085 26 0 0.0 39
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0001934 Census, Compendium Yes 120 0.139 619 88 0.142 4
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0001934 Census, Compendium Yes 114 0.135 547 77 0.141 0
AZU1 AZU1 P20160 Azurocidin chr19 GO:0001934 Not Cancer Driver No 42 0.167 53 13 0.245 0
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0001934 Not Cancer Driver No 55 0.12 402 49 0.122 0
BCAR3_ENST00000260502 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 GO:0001934 Not Cancer Driver No 102 0.124 395 42 0.106 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0001934 Census, Compendium Yes 24 0.1 72 5 0.069 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0001934 Not Cancer Driver No 47 0.19 79 19 0.241 1
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0001934 Not Cancer Driver No 88 0.208 87 13 0.149 0
BMP15 BMP15 O95972 Bone morphogenetic protein 15 chrX GO:0001934 Not Cancer Driver No 91 0.232 81 15 0.185 13
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0001934 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP3 BMP3 P12645 Bone morphogenetic protein 3 chr4 GO:0001934 Not Cancer Driver No 120 0.254 147 48 0.327 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0001934 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0001934 Census Yes 163 0.359 112 62 0.554 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0001934 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0001934 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMP8A BMP8A Q7Z5Y6 Bone morphogenetic protein 8A chr1 GO:0001934 Not Cancer Driver No 26 0.065 93 2 0.022 0
BMP8B BMP8B P34820 Bone morphogenetic protein 8B chr1 GO:0001934 Not Cancer Driver No 21 0.052 90 3 0.033 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0001934 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0001934 Compendium Yes 141 0.136 601 70 0.116 19
BRAF BRAF P15056 Serine/threonine-protein kinase B-raf chr7 GO:0001934 Census, Compendium Yes 791 1.033 310 43 0.139 39
BRAT1 BRAT1 Q6PJG6 BRCA1-associated ATM activator 1 chr7 GO:0001934 Not Cancer Driver No 112 0.136 101 13 0.129 0
BTC BTC P35070 Probetacellulin chr4 GO:0001934 Not Cancer Driver No 29 0.163 12 5 0.417 0
C3 C3 P01024 Complement C3 chr19 GO:0001934 Not Cancer Driver No 337 0.203 287 50 0.174 12
CAB39 CAB39 Q9Y376 Calcium-binding protein 39 chr2 GO:0001934 Not Cancer Driver No 31 0.091 43 5 0.116 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:0001934 Not Cancer Driver No 162 0.342 29 9 0.31 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0001934 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0001934 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0001934 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAMK1 CAMK1 Q14012 Calcium/calmodulin-dependent protein kinase type 1 chr3 GO:0001934 Not Cancer Driver No 40 0.108 31 1 0.032 0
CAMKK2 CAMKK2 Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 chr12 GO:0001934 Not Cancer Driver No 65 0.111 281 35 0.125 0
CAMP CAMP P49913 Cathelicidin antimicrobial peptide chr3 GO:0001934 Not Cancer Driver No 25 0.147 48 4 0.083 0
CARD10_ENST00000251973 CARD10 Q9BWT7 Caspase recruitment domain-containing protein 10 chr22 GO:0001934 Not Cancer Driver No 94 0.091 474 40 0.084 0
CARD14 CARD14 Q9BXL6 Caspase recruitment domain-containing protein 14 chr17 GO:0001934 Not Cancer Driver No 99 0.099 296 36 0.122 11
CASS4 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 GO:0001934 Not Cancer Driver No 204 0.26 496 137 0.276 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0001934 Not Cancer Driver No 30 0.169 2 0 0.0 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0001934 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0001934 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0001934 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0001934 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 GO:0001934 Not Cancer Driver No 49 0.113 145 14 0.097 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0001934 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCND2 CCND2 P30279 G1/S-specific cyclin-D2 chr12 GO:0001934 Census, Compendium Yes 39 0.135 29 7 0.241 5
CCND3 CCND3 P30281 G1/S-specific cyclin-D3 chr6 GO:0001934 Census, Compendium Yes 29 0.099 46 8 0.174 0
CCNK CCNK O75909 Cyclin-K chr14 GO:0001934 Not Cancer Driver No 39 0.067 347 15 0.043 1
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:0001934 Not Cancer Driver No 85 0.117 495 61 0.123 0
CCNT2 CCNT2 O60583 Cyclin-T2 chr2 GO:0001934 Not Cancer Driver No 76 0.104 471 52 0.11 0
CCNY CCNY Q8ND76 Cyclin-Y chr10 GO:0001934 Not Cancer Driver No 38 0.111 94 6 0.064 0
CCNYL1 CCNYL1 Q8N7R7 Cyclin-Y-like protein 1 chr2 GO:0001934 Not Cancer Driver No 31 0.086 100 8 0.08 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0001934 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0001934 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD44 CD44 P16070 CD44 antigen chr11 GO:0001934 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD6 CD6 P30203 T-cell differentiation antigen CD6 chr11 GO:0001934 Not Cancer Driver No 91 0.136 268 41 0.153 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0001934 Census Yes 31 0.105 185 20 0.108 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0001934 Not Cancer Driver No 90 0.274 56 18 0.321 0
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0001934 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDK2AP1 CDK2AP1 O14519 Cyclin-dependent kinase 2-associated protein 1 chr12 GO:0001934 Not Cancer Driver No 10 0.087 76 8 0.105 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0001934 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5R2 CDK5R2 Q13319 Cyclin-dependent kinase 5 activator 2 chr2 GO:0001934 Not Cancer Driver No 14 0.038 204 5 0.025 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:0001934 Not Cancer Driver No 50 0.134 34 2 0.059 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0001934 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0001934 Census, Compendium Yes 19 0.096 198 19 0.096 0
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0001934 Not Cancer Driver No 207 0.152 105 10 0.095 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0001934 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHI3L1 CHI3L1 P36222 Chitinase-3-like protein 1 chr1 GO:0001934 Not Cancer Driver No 66 0.172 24 5 0.208 0
CHRNA3 CHRNA3 P32297 Neuronal acetylcholine receptor subunit alpha-3 chr15 GO:0001934 Not Cancer Driver No 86 0.17 11 1 0.091 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0001934 Not Cancer Driver No 71 0.141 18 4 0.222 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0001934 Not Cancer Driver No 24 0.126 6 1 0.167 0
CKS1B CKS1B P61024 Cyclin-dependent kinases regulatory subunit 1 chr1 GO:0001934 Not Cancer Driver No 10 0.127 10 0 0.0 0
CKS2 CKS2 P33552 Cyclin-dependent kinases regulatory subunit 2 chr9 GO:0001934 Not Cancer Driver No 9 0.114 10 2 0.2 0
CLDN19 CLDN19 Q8N6F1 Claudin-19 chr1 GO:0001934 Not Cancer Driver No 27 0.121 20 2 0.1 3
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0001934 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLIP3_ENST00000593074 CLIP3 Q96DZ5 CAP-Gly domain-containing linker protein 3 chr19 GO:0001934 Not Cancer Driver No 78 0.143 218 22 0.101 0
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:0001934 Not Cancer Driver No 58 0.132 69 10 0.145 9
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0001934 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 GO:0001934 Compendium Yes 42 0.14 30 0 0.0 0
COPS8 COPS8 Q99627 COP9 signalosome complex subunit 8 chr2 GO:0001934 Not Cancer Driver No 25 0.12 14 2 0.143 0
CREBL2 CREBL2 O60519 cAMP-responsive element-binding protein-like 2 chr12 GO:0001934 Not Cancer Driver No 15 0.125 78 5 0.064 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0001934 Not Cancer Driver No 38 0.125 160 25 0.156 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0001934 Census Yes 133 0.137 124 17 0.137 20
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0001934 Not Cancer Driver No 20 0.097 7 0 0.0 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 GO:0001934 Not Cancer Driver No 59 0.142 132 16 0.121 2
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 GO:0001934 Not Cancer Driver No 20 0.093 19 0 0.0 4
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0001934 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0001934 Not Cancer Driver No 80 0.225 0 0 0.0 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0001934 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0001934 Not Cancer Driver No 131 0.11 681 68 0.1 0
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 GO:0001934 Census, Compendium Yes 106 0.143 549 81 0.148 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0001934 Not Cancer Driver No 34 0.108 181 23 0.127 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0001934 Census, Compendium Yes 133 0.201 301 47 0.156 18
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0001934 Not Cancer Driver No 56 0.059 264 11 0.042 0
DIPK2A DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 GO:0001934 Not Cancer Driver No 56 0.13 9 0 0.0 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0001934 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLG3 DLG3 Q92796 Disks large homolog 3 chrX GO:0001934 Not Cancer Driver No 94 0.115 322 30 0.093 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0001934 Not Cancer Driver No 116 0.16 232 55 0.237 0
DOCK3 DOCK3 Q8IZD9 Dedicator of cytokinesis protein 3 chr3 GO:0001934 Not Cancer Driver No 365 0.18 458 69 0.151 0
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 GO:0001934 Not Cancer Driver No 262 0.122 454 53 0.117 0
DOK7 DOK7 Q18PE1 Protein Dok-7 chr4 GO:0001934 Not Cancer Driver No 52 0.103 286 27 0.094 19
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0001934 Not Cancer Driver No 49 0.14 210 25 0.119 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0001934 Not Cancer Driver No 34 0.157 15 5 0.333 0
DVL1 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 GO:0001934 Not Cancer Driver No 73 0.105 434 38 0.088 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0001934 Not Cancer Driver No 96 0.13 514 64 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:0001934 Not Cancer Driver No 97 0.135 437 58 0.133 0
DYNAP DYNAP Q8N1N2 Dynactin-associated protein chr18 GO:0001934 Not Cancer Driver No 54 0.257 78 21 0.269 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0001934 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0001934 Not Cancer Driver No 112 0.253 56 19 0.339 6
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0001934 Not Cancer Driver No 29 0.141 46 5 0.109 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0001934 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0001934 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0001934 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0001934 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0001934 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0001934 Not Cancer Driver No 229 0.143 1079 153 0.142 2
ENG ENG P17813 Endoglin chr9 GO:0001934 Not Cancer Driver No 60 0.091 114 15 0.132 32
EPGN EPGN Q6UW88 Epigen chr4 GO:0001934 Not Cancer Driver No 16 0.104 0 0 0.0 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0001934 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0001934 Census, Compendium Yes 280 0.281 71 15 0.211 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0001934 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0001934 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0001934 Census, Compendium Yes 428 0.327 323 116 0.359 2
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0001934 Not Cancer Driver No 211 0.141 829 117 0.141 9
EREG EREG O14944 Proepiregulin chr4 GO:0001934 Not Cancer Driver No 26 0.154 10 3 0.3 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0001934 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0001934 Not Cancer Driver No 192 0.207 213 45 0.211 0
ERP29 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 GO:0001934 Not Cancer Driver No 29 0.111 34 5 0.147 0
F2 F2 P00734 Prothrombin chr11 GO:0001934 Not Cancer Driver No 115 0.185 97 25 0.258 10
FAM129A NIBAN1 Q9BZQ8 Protein Niban 1 chr1 GO:0001934 Not Cancer Driver No 162 0.175 394 79 0.201 0
FAM20A FAM20A Q96MK3 Pseudokinase FAM20A chr17 GO:0001934 Not Cancer Driver No 62 0.115 94 9 0.096 3
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 GO:0001934 Census, Compendium Yes 55 0.164 62 18 0.29 22
FAXDC2 FAXDC2 Q96IV6 Fatty acid hydroxylase domain-containing protein 2 chr5 GO:0001934 Not Cancer Driver No 39 0.117 9 0 0.0 0
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0001934 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0001934 Census, Compendium Yes 322 0.455 230 38 0.165 0
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 GO:0001934 Not Cancer Driver No 62 0.166 37 5 0.135 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0001934 Not Cancer Driver No 71 0.104 101 10 0.099 0
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0001934 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0001934 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF16 FGF16 O43320 Fibroblast growth factor 16 chrX GO:0001934 Not Cancer Driver No 29 0.14 28 6 0.214 1
FGF17 FGF17 O60258 Fibroblast growth factor 17 chr8 GO:0001934 Not Cancer Driver No 30 0.139 107 16 0.15 3
FGF18 FGF18 O76093 Fibroblast growth factor 18 chr5 GO:0001934 Not Cancer Driver No 40 0.193 57 14 0.246 0
FGF19 FGF19 O95750 Fibroblast growth factor 19 chr11 GO:0001934 Not Cancer Driver No 20 0.093 36 7 0.194 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0001934 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGF20 FGF20 Q9NP95 Fibroblast growth factor 20 chr8 GO:0001934 Not Cancer Driver No 25 0.118 57 3 0.053 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0001934 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF22 FGF22 Q9HCT0 Fibroblast growth factor 22 chr19 GO:0001934 Not Cancer Driver No 15 0.088 42 3 0.071 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0001934 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0001934 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGF3 FGF3 P11487 Fibroblast growth factor 3 chr11 GO:0001934 Not Cancer Driver No 40 0.167 104 24 0.231 2
FGF4 FGF4 P08620 Fibroblast growth factor 4 chr11 GO:0001934 Not Cancer Driver No 16 0.078 21 3 0.143 0
FGF5 FGF5 P12034 Fibroblast growth factor 5 chr4 GO:0001934 Not Cancer Driver No 64 0.239 129 30 0.233 1
FGF6 FGF6 P10767 Fibroblast growth factor 6 chr12 GO:0001934 Not Cancer Driver No 65 0.312 0 0 0.0 0
FGF7 FGF7 P21781 Fibroblast growth factor 7 chr15 GO:0001934 Not Cancer Driver No 38 0.196 22 4 0.182 0
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0001934 Not Cancer Driver No 30 0.129 79 9 0.114 6
FGF9 FGF9 P31371 Fibroblast growth factor 9 chr13 GO:0001934 Not Cancer Driver No 41 0.197 43 10 0.233 1
FIZ1 FIZ1 Q96SL8 Flt3-interacting zinc finger protein 1 chr19 GO:0001934 Not Cancer Driver No 55 0.111 197 22 0.112 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0001934 Census, Compendium Yes 59 0.102 157 19 0.121 5
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0001934 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0001934 Census, Compendium Yes 253 0.186 259 41 0.158 13
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0001934 Not Cancer Driver No 124 0.196 327 70 0.214 3
FNIP1 FNIP1 Q8TF40 Folliculin-interacting protein 1 chr5 GO:0001934 Not Cancer Driver No 143 0.123 384 44 0.115 0
FNIP2 FNIP2 Q9P278 Folliculin-interacting protein 2 chr4 GO:0001934 Not Cancer Driver No 119 0.107 555 71 0.128 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0001934 Not Cancer Driver No 96 0.274 26 5 0.192 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 GO:0001934 Not Cancer Driver No 88 0.142 312 53 0.17 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 GO:0001934 Not Cancer Driver No 68 0.101 388 42 0.108 0
FZD1 FZD1 Q9UP38 Frizzled-1 chr7 GO:0001934 Not Cancer Driver No 78 0.121 133 2 0.015 0
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0001934 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0001934 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0001934 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0001934 Not Cancer Driver No 72 0.104 146 3 0.021 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0001934 Not Cancer Driver No 82 0.121 42 6 0.143 0
GCG GCG P01275 Pro-glucagon chr2 GO:0001934 Not Cancer Driver No 49 0.272 82 22 0.268 0
GDF1 GDF1 P27539 Embryonic growth/differentiation factor 1 chr19 GO:0001934 Not Cancer Driver No 8 0.022 144 5 0.035 6
GDF11 GDF11 O95390 Growth/differentiation factor 11 chr12 GO:0001934 Not Cancer Driver No 40 0.098 109 7 0.064 1
GDF15 GDF15 Q99988 Growth/differentiation factor 15 chr19 GO:0001934 Not Cancer Driver No 39 0.127 143 20 0.14 0
GDF3 GDF3 Q9NR23 Growth/differentiation factor 3 chr12 GO:0001934 Not Cancer Driver No 79 0.217 3 3 1.0 5
GDF5_ENST00000374369 GDF5 P43026 Growth/differentiation factor 5 chr20 GO:0001934 Not Cancer Driver No 104 0.208 255 50 0.196 24
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:0001934 Not Cancer Driver No 91 0.2 225 46 0.204 14
GDF7 GDF7 Q7Z4P5 Growth/differentiation factor 7 chr2 GO:0001934 Not Cancer Driver No 33 0.073 213 8 0.038 0
GDF9 GDF9 O60383 Growth/differentiation factor 9 chr5 GO:0001934 Not Cancer Driver No 72 0.159 53 15 0.283 0
GH1 GH1 P01241 Somatotropin chr17 GO:0001934 Not Cancer Driver No 54 0.249 24 9 0.375 15
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0001934 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0001934 Not Cancer Driver No 173 0.271 229 66 0.288 19
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0001934 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPNMB GPNMB Q14956 Transmembrane glycoprotein NMB chr7 GO:0001934 Not Cancer Driver No 89 0.156 94 18 0.191 0
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 GO:0001934 Not Cancer Driver No 82 0.203 75 19 0.253 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0001934 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0001934 Not Cancer Driver No 312 0.257 323 51 0.158 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0001934 Not Cancer Driver No 44 0.158 219 32 0.146 2
HBEGF HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:0001934 Not Cancer Driver No 16 0.077 63 3 0.048 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0001934 Not Cancer Driver No 103 0.212 446 94 0.211 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0001934 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0001934 Not Cancer Driver No 178 0.147 409 59 0.144 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0001934 Not Cancer Driver No 55 0.158 27 2 0.074 11
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0001934 Compendium Yes 233 0.32 43 16 0.372 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0001934 Not Cancer Driver No 154 0.129 686 96 0.14 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0001934 Not Cancer Driver No 48 0.18 12 1 0.083 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0001934 Census, Compendium Yes 107 0.566 16 4 0.25 18
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0001934 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0001934 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 GO:0001934 Not Cancer Driver No 93 0.146 286 38 0.133 0
IFNA10 IFNA10 P01566 Interferon alpha-10 chr9 GO:0001934 Not Cancer Driver No 40 0.212 1 0 0.0 0
IFNA13_ENST00000449498 IFNA13 P01562 Interferon alpha-1/13 chr9 GO:0001934 Not Cancer Driver No 39 0.206 2 0 0.0 0
IFNA14 IFNA14 P01570 Interferon alpha-14 chr9 GO:0001934 Not Cancer Driver No 39 0.206 1 1 1.0 0
IFNA16 IFNA16 P05015 Interferon alpha-16 chr9 GO:0001934 Not Cancer Driver No 61 0.323 1 0 0.0 0
IFNA17 IFNA17 P01571 Interferon alpha-17 chr9 GO:0001934 Not Cancer Driver No 37 0.196 0 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0001934 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNA21 IFNA21 P01568 Interferon alpha-21 chr9 GO:0001934 Not Cancer Driver No 34 0.18 0 0 0.0 0
IFNA4 IFNA4 P05014 Interferon alpha-4 chr9 GO:0001934 Not Cancer Driver No 39 0.206 1 0 0.0 0
IFNA5 IFNA5 P01569 Interferon alpha-5 chr9 GO:0001934 Not Cancer Driver No 36 0.19 1 0 0.0 0
IFNA6 IFNA6 P05013 Interferon alpha-6 chr9 GO:0001934 Not Cancer Driver No 28 0.148 4 0 0.0 0
IFNA7 IFNA7 P01567 Interferon alpha-7 chr9 GO:0001934 Not Cancer Driver No 43 0.228 1 1 1.0 0
IFNA8 IFNA8 P32881 Interferon alpha-8 chr9 GO:0001934 Not Cancer Driver No 43 0.228 0 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0001934 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNE IFNE Q86WN2 Interferon epsilon chr9 GO:0001934 Not Cancer Driver No 30 0.144 17 4 0.235 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0001934 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNK IFNK Q9P0W0 Interferon kappa chr9 GO:0001934 Not Cancer Driver No 17 0.082 23 0 0.0 0
IFNW1 IFNW1 P05000 Interferon omega-1 chr9 GO:0001934 Not Cancer Driver No 32 0.164 10 3 0.3 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0001934 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0001934 Not Cancer Driver No 39 0.217 44 12 0.273 0
IL11 IL11 P20809 Interleukin-11 chr19 GO:0001934 Not Cancer Driver No 19 0.095 69 8 0.116 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0001934 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0001934 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0001934 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0001934 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0001934 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0001934 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0001934 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0001934 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0001934 Not Cancer Driver No 55 0.118 165 23 0.139 1
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 GO:0001934 Not Cancer Driver No 45 0.1 71 9 0.127 0
INHA INHA P05111 Inhibin alpha chain chr2 GO:0001934 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0001934 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0001934 Not Cancer Driver No 61 0.15 98 5 0.051 0
INHBC INHBC P55103 Inhibin beta C chain chr12 GO:0001934 Not Cancer Driver No 52 0.148 35 3 0.086 0
INHBE INHBE P58166 Inhibin beta E chain chr12 GO:0001934 Not Cancer Driver No 52 0.149 85 12 0.141 0
INS INS P01308 Insulin chr11 GO:0001934 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:0001934 Not Cancer Driver No 190 0.137 280 57 0.204 64
IQGAP3 IQGAP3 Q86VI3 Ras GTPase-activating-like protein IQGAP3 chr1 GO:0001934 Not Cancer Driver No 233 0.143 257 36 0.14 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0001934 Compendium Yes 71 0.1 337 39 0.116 0
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0001934 Not Cancer Driver No 9 0.05 45 1 0.022 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0001934 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0001934 Not Cancer Driver No 124 0.157 66 5 0.076 30
ITLN1 ITLN1 Q8WWA0 Intelectin-1 chr1 GO:0001934 Not Cancer Driver No 72 0.23 13 4 0.308 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0001934 Census, Compendium Yes 136 0.12 59 5 0.085 5
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0001934 Census, Compendium Yes 357 0.263 275 55 0.2 2
KNDC1 KNDC1 Q76NI1 Kinase non-catalytic C-lobe domain-containing protein 1 chr10 GO:0001934 Not Cancer Driver No 276 0.158 805 124 0.154 0
KRAS KRAS P01116 GTPase KRas chr12 GO:0001934 Census, Compendium Yes 788 4.169 7 2 0.286 27
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:0001934 Census, Compendium Yes 161 0.142 788 100 0.127 0
LEFTY1 LEFTY1 O75610 Left-right determination factor 1 chr1 GO:0001934 Not Cancer Driver No 55 0.15 65 8 0.123 0
LEFTY2 LEFTY2 O00292 Left-right determination factor 2 chr1 GO:0001934 Not Cancer Driver No 38 0.104 54 4 0.074 1
LEP LEP P41159 Leptin chr7 GO:0001934 Not Cancer Driver No 29 0.174 0 0 0.0 2
LEPR LEPR P48357 Leptin receptor chr1 GO:0001934 Not Cancer Driver No 243 0.209 57 11 0.193 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0001934 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRA5 LILRA5 A6NI73 Leukocyte immunoglobulin-like receptor subfamily A member 5 chr19 GO:0001934 Not Cancer Driver No 79 0.264 98 19 0.194 0
LIMCH1_ENST00000313860 LIMCH1 Q9UPQ0 LIM and calponin homology domains-containing protein 1 chr4 GO:0001934 Not Cancer Driver No 177 0.163 880 140 0.159 0
LIMK2_ENST00000331728 LIMK2 P53671 LIM domain kinase 2 chr22 GO:0001934 Not Cancer Driver No 93 0.146 146 29 0.199 0
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0001934 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0001934 Not Cancer Driver No 519 0.205 90 17 0.189 23
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0001934 Census Yes 95 0.186 84 12 0.143 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0001934 Not Cancer Driver No 22 0.104 0 0 0.0 1
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0001934 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0001934 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0001934 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0001934 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0001934 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0001934 Census Yes 157 0.163 593 91 0.153 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0001934 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0001934 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0001934 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0001934 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0001934 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0001934 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPKAP1 MAPKAP1 Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 chr9 GO:0001934 Not Cancer Driver No 70 0.134 173 25 0.145 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 GO:0001934 Not Cancer Driver No 37 0.132 120 16 0.133 0
MARCO MARCO Q9UEW3 Macrophage receptor MARCO chr2 GO:0001934 Not Cancer Driver No 180 0.346 323 125 0.387 0
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 GO:0001934 Not Cancer Driver No 47 0.145 5 2 0.4 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0001934 Not Cancer Driver No 70 0.13 411 58 0.141 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0001934 Not Cancer Driver No 4 0.035 0 0 0.0 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0001934 Not Cancer Driver No 129 0.182 124 26 0.21 0
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:0001934 Not Cancer Driver No 23 0.074 64 2 0.031 0
MOB1A MOB1A Q9H8S9 MOB kinase activator 1A chr2 GO:0001934 Not Cancer Driver No 16 0.074 10 2 0.2 0
MOB1B_ENST00000309395 MOB1B Q7L9L4 MOB kinase activator 1B chr4 GO:0001934 Not Cancer Driver No 17 0.079 7 0 0.0 0
MOB2_ENST00000614710 MOB2 Q70IA6 MOB kinase activator 2 chr11 GO:0001934 Not Cancer Driver No 22 0.093 46 0 0.0 0
MOB3A MOB3A Q96BX8 MOB kinase activator 3A chr19 GO:0001934 Not Cancer Driver No 26 0.12 16 1 0.062 0
MOB3B MOB3B Q86TA1 MOB kinase activator 3B chr9 GO:0001934 Not Cancer Driver No 29 0.134 16 2 0.125 0
MOB3C_ENST00000371940 MOB3C Q70IA8 MOB kinase activator 3C chr1 GO:0001934 Not Cancer Driver No 38 0.176 1 0 0.0 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0001934 Not Cancer Driver No 84 0.119 292 35 0.12 1
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0001934 Not Cancer Driver No 68 0.181 64 11 0.172 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0001934 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTCP1_ENST00000362018 MTCP1 P56278 Protein p13 MTCP-1 chrX GO:0001934 Census, Compendium Yes 14 0.131 6 0 0.0 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0001934 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUSK MUSK O15146 Muscle, skeletal receptor tyrosine-protein kinase chr9 GO:0001934 Not Cancer Driver No 188 0.216 35 7 0.2 7
MYDGF MYDGF Q969H8 Myeloid-derived growth factor chr19 GO:0001934 Not Cancer Driver No 23 0.133 26 4 0.154 0
NAB2 NAB2 Q15742 NGFI-A-binding protein 2 chr12 GO:0001934 Census Yes 67 0.128 395 51 0.129 0
NBN NBN O60934 Nibrin chr8 GO:0001934 Census Yes 90 0.119 417 54 0.129 1
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0001934 Not Cancer Driver No 37 0.095 181 12 0.066 1
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0001934 Not Cancer Driver No 106 0.127 516 72 0.14 0
NEK10_ENST00000429845 NEK10 Q6ZWH5 Serine/threonine-protein kinase Nek10 chr3 GO:0001934 Not Cancer Driver No 213 0.182 281 60 0.214 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0001934 Not Cancer Driver No 62 0.108 153 11 0.072 0
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0001934 Not Cancer Driver No 66 0.274 93 25 0.269 1
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0001934 Not Cancer Driver No 35 0.15 171 16 0.094 0
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0001934 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0001934 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0001934 Not Cancer Driver No 123 0.213 0 0 0.0 0
NPTN NPTN Q9Y639 Neuroplastin chr15 GO:0001934 Not Cancer Driver No 47 0.118 118 9 0.076 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0001934 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRG3_ENST00000404547 NRG3 P56975 Pro-neuregulin-3, membrane-bound isoform chr10 GO:0001934 Not Cancer Driver No 227 0.315 425 134 0.315 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0001934 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTF4 NTF4 P34130 Neurotrophin-4 chr19 GO:0001934 Not Cancer Driver No 21 0.1 56 4 0.071 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0001934 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0001934 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0001934 Census, Compendium Yes 249 0.297 57 21 0.368 0
ODAM ODAM A1E959 Odontogenic ameloblast-associated protein chr4 GO:0001934 Not Cancer Driver No 51 0.183 140 18 0.129 0
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0001934 Not Cancer Driver No 91 0.245 30 3 0.1 0
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 GO:0001934 Not Cancer Driver No 105 0.118 401 37 0.092 0
OSM OSM P13725 Oncostatin-M chr22 GO:0001934 Not Cancer Driver No 43 0.171 114 24 0.211 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0001934 Not Cancer Driver No 60 0.161 16 1 0.062 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0001934 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0001934 Compendium Yes 89 0.17 242 49 0.202 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0001934 Not Cancer Driver No 11 0.058 30 0 0.0 5
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0001934 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDE8A_ENST00000394553 PDE8A O60658 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A chr15 GO:0001934 Not Cancer Driver No 78 0.094 187 17 0.091 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0001934 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0001934 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0001934 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0001934 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0001934 Not Cancer Driver No 33 0.059 121 12 0.099 0
PECAM1 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 GO:0001934 Not Cancer Driver No 2 0.003 153 2 0.013 0
PELI2 PELI2 Q9HAT8 E3 ubiquitin-protein ligase pellino homolog 2 chr14 GO:0001934 Not Cancer Driver No 80 0.19 162 38 0.235 0
PFN2 PFN2 P35080 Profilin-2 chr3 GO:0001934 Not Cancer Driver No 20 0.143 0 0 0.0 0
PGF_ENST00000405431 PGF P49763 Placenta growth factor chr14 GO:0001934 Not Cancer Driver No 30 0.136 72 10 0.139 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0001934 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0001934 Not Cancer Driver No 37 0.136 4 1 0.25 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0001934 Not Cancer Driver No 83 0.11 419 45 0.107 2
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0001934 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 GO:0001934 Not Cancer Driver No 51 0.111 149 20 0.134 0
PILRB PILRB Q9UKJ0 Paired immunoglobulin-like type 2 receptor beta chr7 GO:0001934 Not Cancer Driver No 29 0.128 26 3 0.115 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0001934 Not Cancer Driver No 17 0.104 115 12 0.104 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0001934 Not Cancer Driver No 57 0.098 99 13 0.131 23
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:0001934 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0001934 Not Cancer Driver No 113 0.117 375 35 0.093 10
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0001934 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 GO:0001934 Not Cancer Driver No 49 0.146 18 5 0.278 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0001934 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0001934 Not Cancer Driver No 87 0.144 119 13 0.109 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0001934 Census Yes 72 0.143 44 4 0.091 3
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0001934 Not Cancer Driver No 11 0.067 24 3 0.125 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:0001934 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0001934 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0001934 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0001934 Compendium Yes 118 0.134 246 34 0.138 0
PRLR PRLR P16471 Prolactin receptor chr5 GO:0001934 Not Cancer Driver No 154 0.248 282 70 0.248 2
PRNP PRNP P04156 Major prion protein chr20 GO:0001934 Not Cancer Driver No 36 0.142 115 7 0.061 18
PROM2_ENST00000403131 PROM2 Q8N271 Prominin-2 chr2 GO:0001934 Not Cancer Driver No 111 0.133 34 4 0.118 0
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0001934 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRR5L PRR5L Q6MZQ0 Proline-rich protein 5-like chr11 GO:0001934 Not Cancer Driver No 57 0.155 108 12 0.111 0
PRR5_ENST00000336985 PRR5 P85299 Proline-rich protein 5 chr22 GO:0001934 Not Cancer Driver No 50 0.129 173 22 0.127 0
PRRC1_ENST00000296666 PRRC1 Q96M27 Protein PRRC1 chr5 GO:0001934 Not Cancer Driver No 42 0.094 235 24 0.102 0
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0001934 Not Cancer Driver No 20 0.088 53 5 0.094 0
PSRC1_ENST00000409138 PSRC1 Q6PGN9 Proline/serine-rich coiled-coil protein 1 chr1 GO:0001934 Not Cancer Driver No 30 0.083 361 30 0.083 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0001934 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0001934 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0001934 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0001934 Not Cancer Driver No 49 0.113 140 25 0.179 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0001934 Census, Compendium Yes 66 0.344 2 1 0.5 6
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0001934 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0001934 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0001934 Census, Compendium Yes 89 0.137 169 38 0.225 22
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0001934 Not Cancer Driver No 36 0.175 35 5 0.143 0
RALBP1 RALBP1 Q15311 RalA-binding protein 1 chr18 GO:0001934 Not Cancer Driver No 65 0.099 381 46 0.121 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0001934 Not Cancer Driver No 30 0.203 0 0 0.0 0
RAP2A RAP2A P10114 Ras-related protein Rap-2a chr13 GO:0001934 Not Cancer Driver No 15 0.082 9 0 0.0 0
RAP2B RAP2B P61225 Ras-related protein Rap-2b chr3 GO:0001934 Not Cancer Driver No 22 0.12 0 0 0.0 0
RAP2C_ENST00000370874 RAP2C Q9Y3L5 Ras-related protein Rap-2c chrX GO:0001934 Not Cancer Driver No 32 0.175 8 2 0.25 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0001934 Not Cancer Driver No 216 0.144 803 116 0.144 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0001934 Not Cancer Driver No 97 0.105 197 19 0.096 0
RARRES2 RARRES2 Q99969 Retinoic acid receptor responder protein 2 chr7 GO:0001934 Not Cancer Driver No 16 0.098 14 2 0.143 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0001934 Not Cancer Driver No 96 0.12 191 12 0.063 1
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 GO:0001934 Not Cancer Driver No 90 0.276 126 44 0.349 0
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 GO:0001934 Not Cancer Driver No 202 0.127 578 75 0.13 0
RBPMS_ENST00000320203 RBPMS Q93062 RNA-binding protein with multiple splicing chr8 GO:0001934 Not Cancer Driver No 23 0.117 87 11 0.126 0
RELN RELN P78509 Reelin chr7 GO:0001934 Not Cancer Driver No 761 0.22 107 19 0.178 7
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0001934 Census, Compendium Yes 208 0.187 105 12 0.114 139
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0001934 Not Cancer Driver No 9 0.066 81 7 0.086 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0001934 Compendium Yes 82 0.122 277 39 0.141 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0001934 Not Cancer Driver No 63 0.117 143 20 0.14 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0001934 Not Cancer Driver No 145 0.104 732 81 0.111 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0001934 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0001934 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS6KA4 RPS6KA4 O75676 Ribosomal protein S6 kinase alpha-4 chr11 GO:0001934 Not Cancer Driver No 72 0.093 220 11 0.05 0
RPS6KA5 RPS6KA5 O75582 Ribosomal protein S6 kinase alpha-5 chr14 GO:0001934 Not Cancer Driver No 97 0.121 187 18 0.096 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0001934 Not Cancer Driver No 176 0.132 241 21 0.087 0
RSPO1_ENST00000401068 RSPO1 Q2MKA7 R-spondin-1 chr1 GO:0001934 Not Cancer Driver No 59 0.224 82 16 0.195 0
S1PR2 S1PR2 O95136 Sphingosine 1-phosphate receptor 2 chr19 GO:0001934 Not Cancer Driver No 38 0.108 16 3 0.188 2
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0001934 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0001934 Not Cancer Driver No 39 0.131 17 2 0.118 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0001934 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMA7A SEMA7A O75326 Semaphorin-7A chr15 GO:0001934 Not Cancer Driver No 81 0.122 150 21 0.14 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0001934 Not Cancer Driver No 47 0.159 1 0 0.0 0
SH2D3A SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 GO:0001934 Not Cancer Driver No 68 0.118 305 40 0.131 0
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 GO:0001934 Not Cancer Driver No 110 0.128 440 72 0.164 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0001934 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0001934 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLCO3A1 SLCO3A1 Q9UIG8 Solute carrier organic anion transporter family member 3A1 chr15 GO:0001934 Not Cancer Driver No 140 0.197 64 9 0.141 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0001934 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0001934 Not Cancer Driver No 59 0.138 2 0 0.0 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0001934 Not Cancer Driver No 21 0.15 107 13 0.121 5
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0001934 Compendium Yes 86 0.169 495 82 0.166 18
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 GO:0001934 Not Cancer Driver No 30 0.088 179 11 0.061 0
SPDYA_ENST00000379579 SPDYA Q5MJ70 Speedy protein A chr2 GO:0001934 Not Cancer Driver No 39 0.125 119 11 0.092 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0001934 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0001934 Not Cancer Driver No 46 0.146 169 29 0.172 1
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 GO:0001934 Not Cancer Driver No 54 0.123 267 32 0.12 30
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0001934 Census Yes 53 0.099 130 11 0.085 1
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0001934 Not Cancer Driver No 66 0.224 103 18 0.175 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0001934 Not Cancer Driver No 70 0.144 231 30 0.13 0
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:0001934 Not Cancer Driver No 121 0.122 659 83 0.126 2
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0001934 Census Yes 96 0.151 131 27 0.206 5
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0001934 Census Yes 54 0.163 305 53 0.174 0
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0001934 Not Cancer Driver No 191 0.155 666 102 0.153 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0001934 Not Cancer Driver No 123 0.137 494 64 0.13 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0001934 Not Cancer Driver No 101 0.139 42 5 0.119 12
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0001934 Not Cancer Driver No 35 0.088 197 12 0.061 4
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0001934 Not Cancer Driver No 21 0.198 33 7 0.212 0
TCL1A TCL1A P56279 T-cell leukemia/lymphoma protein 1A chr14 GO:0001934 Census Yes 30 0.263 5 1 0.2 0
TCL1B TCL1B O95988 T-cell leukemia/lymphoma protein 1B chr14 GO:0001934 Not Cancer Driver No 38 0.297 11 1 0.091 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0001934 Not Cancer Driver No 219 0.195 126 22 0.175 10
TENM1_ENST00000371130 TENM1 Q9UKZ4 Teneurin-1 chrX GO:0001934 Not Cancer Driver No 728 0.267 482 164 0.34 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0001934 Not Cancer Driver No 28 0.07 310 16 0.052 0
TESK1_ENST00000336395 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 GO:0001934 Not Cancer Driver No 63 0.101 339 35 0.103 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0001934 Census Yes 89 0.117 80 6 0.075 1
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 GO:0001934 Not Cancer Driver No 20 0.125 0 0 0.0 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0001934 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0001934 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0001934 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0001934 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0001934 Census, Compendium Yes 106 0.187 60 16 0.267 25
THPO THPO P40225 Thrombopoietin chr3 GO:0001934 Not Cancer Driver No 63 0.178 163 25 0.153 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0001934 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0001934 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0001934 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0001934 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMEM119 TMEM119 Q4V9L6 Transmembrane protein 119 chr12 GO:0001934 Not Cancer Driver No 59 0.208 195 47 0.241 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0001934 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 GO:0001934 Not Cancer Driver No 55 0.118 174 17 0.098 0
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 GO:0001934 Not Cancer Driver No 44 0.1 190 19 0.1 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0001934 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFSF15 TNFSF15 O95150 Tumor necrosis factor ligand superfamily member 15 chr9 GO:0001934 Not Cancer Driver No 41 0.163 49 12 0.245 0
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 GO:0001934 Not Cancer Driver No 254 0.187 781 156 0.2 0
TNKS1BP1 TNKS1BP1 Q9C0C2 182 kDa tankyrase-1-binding protein chr11 GO:0001934 Not Cancer Driver No 221 0.128 1712 219 0.128 0
TOM1L1 TOM1L1 O75674 TOM1-like protein 1 chr17 GO:0001934 Not Cancer Driver No 51 0.107 268 29 0.108 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0001934 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF4 TRAF4 Q9BUZ4 TNF receptor-associated factor 4 chr17 GO:0001934 Not Cancer Driver No 42 0.089 27 1 0.037 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0001934 Not Cancer Driver No 67 0.128 62 7 0.113 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0001934 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0001934 Not Cancer Driver No 86 0.176 47 15 0.319 0
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0001934 Not Cancer Driver No 255 0.262 148 32 0.216 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0001934 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TTK TTK P33981 Dual specificity protein kinase TTK chr6 GO:0001934 Not Cancer Driver No 136 0.159 352 46 0.131 0
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0001934 Not Cancer Driver No 27 0.121 19 3 0.158 0
TXN TXN P10599 Thioredoxin chr9 GO:0001934 Not Cancer Driver No 6 0.057 0 0 0.0 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0001934 Not Cancer Driver No 24 0.12 33 3 0.091 0
UCN UCN P55089 Urocortin chr2 GO:0001934 Not Cancer Driver No 7 0.056 61 4 0.066 0
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 GO:0001934 Not Cancer Driver No 20 0.083 89 4 0.045 1
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0001934 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFB VEGFB P49765 Vascular endothelial growth factor B chr11 GO:0001934 Not Cancer Driver No 25 0.121 125 22 0.176 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0001934 Not Cancer Driver No 128 0.305 37 12 0.324 0
VEGFD VEGFD O43915 Vascular endothelial growth factor D chrX GO:0001934 Not Cancer Driver No 59 0.167 33 6 0.182 0
WDFY2 WDFY2 Q96P53 WD repeat and FYVE domain-containing protein 2 chr13 GO:0001934 Not Cancer Driver No 49 0.122 20 2 0.1 0
WNK3_ENST00000375159 WNK3 Q9BYP7 Serine/threonine-protein kinase WNK3 chrX GO:0001934 Not Cancer Driver No 281 0.156 1281 200 0.156 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0001934 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0001934 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0001934 Not Cancer Driver No 66 0.174 0 0 0.0 2
ZFP91 ZFP91 Q96JP5 E3 ubiquitin-protein ligase ZFP91 chr11 GO:0001934 Not Cancer Driver No 85 0.149 383 55 0.144 0