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Total number of protein in "GO:0001067" GO term:  137

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0001067 Not Cancer Driver No 129 0.152 351 75 0.214 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0001067 Not Cancer Driver No 71 0.113 332 40 0.12 0
ARNTL2 ARNTL2 Q8WYA1 Aryl hydrocarbon receptor nuclear translocator-like protein 2 chr12 GO:0001067 Not Cancer Driver No 79 0.124 264 38 0.144 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0001067 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASCL2 ASCL2 Q99929 Achaete-scute homolog 2 chr11 GO:0001067 Not Cancer Driver No 2 0.01 166 1 0.006 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0001067 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0001067 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0001067 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATF7_ENST00000456903 ATF7 P17544 Cyclic AMP-dependent transcription factor ATF-7 chr12 GO:0001067 Not Cancer Driver No 45 0.093 468 45 0.096 0
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0001067 Not Cancer Driver No 31 0.097 254 23 0.091 0
BAZ2A BAZ2A Q9UIF9 Bromodomain adjacent to zinc finger domain protein 2A chr12 GO:0001067 Not Cancer Driver No 186 0.098 1283 118 0.092 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0001067 Census, Compendium Yes 134 0.19 328 67 0.204 0
BHLHE40 BHLHE40 O14503 Class E basic helix-loop-helix protein 40 chr3 GO:0001067 Not Cancer Driver No 52 0.126 242 31 0.128 0
BHLHE41 BHLHE41 Q9C0J9 Class E basic helix-loop-helix protein 41 chr12 GO:0001067 Not Cancer Driver No 21 0.044 213 10 0.047 0
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 GO:0001067 Not Cancer Driver No 90 0.133 399 45 0.113 4
BRF2 BRF2 Q9HAW0 Transcription factor IIIB 50 kDa subunit chr8 GO:0001067 Not Cancer Driver No 40 0.095 138 13 0.094 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0001067 Not Cancer Driver No 3 0.009 276 2 0.007 0
CIART CIART Q8N365 Circadian-associated transcriptional repressor chr1 GO:0001067 Not Cancer Driver No 59 0.153 272 40 0.147 0
CLOCK CLOCK O15516 Circadian locomoter output cycles protein kaput chr4 GO:0001067 Not Cancer Driver No 83 0.098 458 38 0.083 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0001067 Census Yes 25 0.076 277 23 0.083 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0001067 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0001067 Census Yes 68 0.131 372 50 0.134 0
CREB3L2 CREB3L2 Q70SY1 Cyclic AMP-responsive element-binding protein 3-like protein 2 chr7 GO:0001067 Census Yes 61 0.117 364 46 0.126 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:0001067 Not Cancer Driver No 96 0.208 338 67 0.198 1
CREB3L4_ENST00000271889 CREB3L4 Q8TEY5 Cyclic AMP-responsive element-binding protein 3-like protein 4 chr1 GO:0001067 Not Cancer Driver No 55 0.139 241 27 0.112 0
CREB5 CREB5 Q02930 Cyclic AMP-responsive element-binding protein 5 chr7 GO:0001067 Not Cancer Driver No 92 0.181 494 89 0.18 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0001067 Not Cancer Driver No 76 0.13 91 5 0.055 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0001067 Compendium Yes 182 0.143 331 42 0.127 0
E4F1 E4F1 Q66K89 Transcription factor E4F1 chr16 GO:0001067 Not Cancer Driver No 84 0.107 462 46 0.1 0
ELK3 ELK3 P41970 ETS domain-containing protein Elk-3 chr12 GO:0001067 Not Cancer Driver No 58 0.143 163 16 0.098 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0001067 Census, Compendium Yes 121 0.203 195 27 0.138 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 GO:0001067 Not Cancer Driver No 90 0.17 92 11 0.12 1
ESRRG_ENST00000408911 ESRRG P62508 Estrogen-related receptor gamma chr1 GO:0001067 Not Cancer Driver No 135 0.295 76 29 0.382 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0001067 Census, Compendium Yes 120 0.161 284 44 0.155 11
FIGLA FIGLA Q6QHK4 Factor in the germline alpha chr2 GO:0001067 Not Cancer Driver No 22 0.1 154 17 0.11 0
FOS FOS P01100 Protein c-Fos chr14 GO:0001067 Not Cancer Driver No 45 0.118 245 33 0.135 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0001067 Census, Compendium Yes 111 0.251 364 87 0.239 2
GBX2 GBX2 P52951 Homeobox protein GBX-2 chr2 GO:0001067 Not Cancer Driver No 43 0.124 243 31 0.128 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0001067 Not Cancer Driver No 95 0.152 258 43 0.167 2
GTF2A1 GTF2A1 P52655 Transcription initiation factor IIA subunit 1 chr14 GO:0001067 Not Cancer Driver No 49 0.13 260 38 0.146 0
GTF2B GTF2B Q00403 Transcription initiation factor IIB chr1 GO:0001067 Not Cancer Driver No 33 0.104 80 6 0.075 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0001067 Not Cancer Driver No 46 0.124 125 19 0.152 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 GO:0001067 Not Cancer Driver No 23 0.18 71 16 0.225 0
H3F3A_ENST00000366816 H3-3B P84243 Histone H3.3 chr1 GO:0001067 Not Cancer Driver No 32 0.235 51 22 0.431 3
H3F3B_ENST00000589599 H3-3B P84243 Histone H3.3 chr17 GO:0001067 Not Cancer Driver No 28 0.206 51 14 0.275 3
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0001067 Not Cancer Driver No 47 0.217 124 29 0.234 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0001067 Not Cancer Driver No 47 0.098 135 10 0.074 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0001067 Not Cancer Driver No 37 0.132 226 32 0.142 0
HES3 HES3 Q5TGS1 Transcription factor HES-3 chr1 GO:0001067 Not Cancer Driver No 13 0.07 129 10 0.078 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0001067 Census Yes 118 0.143 435 51 0.117 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0001067 Census Yes 12 0.11 109 12 0.11 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0001067 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSF2 HSF2 Q03933 Heat shock factor protein 2 chr6 GO:0001067 Not Cancer Driver No 64 0.119 292 37 0.127 0
JDP2_ENST00000435893 JDP2 Q8WYK2 Jun dimerization protein 2 chr14 GO:0001067 Not Cancer Driver No 16 0.098 142 13 0.092 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0001067 Census Yes 35 0.106 281 25 0.089 0
LIN54 LIN54 Q6MZP7 Protein lin-54 homolog chr4 GO:0001067 Not Cancer Driver No 61 0.081 440 31 0.07 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 GO:0001067 Not Cancer Driver No 99 0.103 175 15 0.086 10
MAF1_ENST00000532522 MAF1 Q9H063 Repressor of RNA polymerase III transcription MAF1 homolog chr8 GO:0001067 Not Cancer Driver No 22 0.086 74 4 0.054 0
MAX MAX P61244 Protein max chr14 GO:0001067 Census, Compendium Yes 45 0.281 160 45 0.281 9
MBNL1_ENST00000463374 MBNL1 Q9NR56 Muscleblind-like protein 1 chr3 GO:0001067 Not Cancer Driver No 56 0.144 153 20 0.131 0
MITF_ENST00000448226 MITF O75030 Microphthalmia-associated transcription factor chr3 GO:0001067 Census Yes 80 0.152 408 69 0.169 7
MLXIPL MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0001067 Not Cancer Driver No 106 0.124 554 66 0.119 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0001067 Census, Compendium Yes 379 0.149 296 37 0.125 18
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0001067 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0001067 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYF5 MYF5 P13349 Myogenic factor 5 chr12 GO:0001067 Not Cancer Driver No 103 0.404 122 60 0.492 1
MYF6 MYF6 P23409 Myogenic factor 6 chr12 GO:0001067 Not Cancer Driver No 89 0.368 118 44 0.373 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0001067 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0001067 Not Cancer Driver No 36 0.161 132 20 0.152 0
NCOA2 NCOA2 Q15596 Nuclear receptor coactivator 2 chr8 GO:0001067 Census, Compendium Yes 210 0.143 1281 185 0.144 0
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0001067 Not Cancer Driver No 84 0.236 202 52 0.257 2
NEUROD2 NEUROD2 Q15784 Neurogenic differentiation factor 2 chr17 GO:0001067 Not Cancer Driver No 26 0.068 210 14 0.067 2
NEUROG1 NEUROG1 Q92886 Neurogenin-1 chr5 GO:0001067 Not Cancer Driver No 27 0.114 178 18 0.101 0
NEUROG2 NEUROG2 Q9H2A3 Neurogenin-2 chr4 GO:0001067 Not Cancer Driver No 32 0.118 209 29 0.139 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 GO:0001067 Census, Compendium Yes 41 0.111 334 39 0.117 7
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0001067 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0001067 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR2F1_ENST00000327111 NR2F1 P10589 COUP transcription factor 1 chr5 GO:0001067 Not Cancer Driver No 67 0.158 110 6 0.055 4
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0001067 Census Yes 83 0.133 298 37 0.124 0
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0001067 Not Cancer Driver No 72 0.171 337 56 0.166 38
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0001067 Census Yes 160 0.124 948 116 0.122 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0001067 Not Cancer Driver No 30 0.103 157 13 0.083 0
POLRMT POLRMT O00411 DNA-directed RNA polymerase, mitochondrial chr19 GO:0001067 Not Cancer Driver No 188 0.153 253 31 0.123 0
POU2F1_ENST00000541643 POU2F1 P14859 POU domain, class 2, transcription factor 1 chr1 GO:0001067 Not Cancer Driver No 95 0.128 433 50 0.115 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0001067 Census Yes 72 0.143 44 4 0.091 3
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:0001067 Not Cancer Driver No 22 0.103 0 0 0.0 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0001067 Not Cancer Driver No 83 0.13 72 6 0.083 0
PTF1A PTF1A Q7RTS3 Pancreas transcription factor 1 subunit alpha chr10 GO:0001067 Not Cancer Driver No 35 0.107 231 31 0.134 0
PURA PURA Q00577 Transcriptional activator protein Pur-alpha chr5 GO:0001067 Not Cancer Driver No 22 0.068 188 10 0.053 6
PURB PURB Q96QR8 Transcriptional activator protein Pur-beta chr7 GO:0001067 Not Cancer Driver No 27 0.087 161 14 0.087 0
PURG PURG Q9UJV8 Purine-rich element-binding protein gamma chr8 GO:0001067 Not Cancer Driver No 69 0.199 174 29 0.167 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0001067 Census, Compendium Yes 70 0.152 167 14 0.084 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0001067 Compendium Yes 75 0.136 400 48 0.12 0
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0001067 Not Cancer Driver No 142 0.129 868 113 0.13 4
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0001067 Not Cancer Driver No 176 0.132 241 21 0.087 0
RRN3 RRN3 Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 chr16 GO:0001067 Not Cancer Driver No 66 0.101 115 15 0.13 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0001067 Not Cancer Driver No 62 0.134 100 13 0.13 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 GO:0001067 Compendium Yes 90 0.195 184 26 0.141 0
RXRB_ENST00000374680 RXRB P28702 Retinoic acid receptor RXR-beta chr6 GO:0001067 Not Cancer Driver No 61 0.114 279 25 0.09 0
RXRG RXRG P48443 Retinoic acid receptor RXR-gamma chr1 GO:0001067 Not Cancer Driver No 103 0.222 161 41 0.255 0
SCRT2 SCRT2 Q9NQ03 Transcriptional repressor scratch 2 chr20 GO:0001067 Not Cancer Driver No 19 0.062 168 4 0.024 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0001067 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0001067 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0001067 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0001067 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0001067 Not Cancer Driver No 59 0.138 2 0 0.0 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0001067 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0001067 Not Cancer Driver No 52 0.194 52 9 0.173 0
SNAPC3_ENST00000610884 SNAPC3 Q92966 snRNA-activating protein complex subunit 3 chr9 GO:0001067 Not Cancer Driver No 30 0.073 99 2 0.02 0
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0001067 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0001067 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRF SRF P11831 Serum response factor chr6 GO:0001067 Not Cancer Driver No 44 0.087 443 42 0.095 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0001067 Not Cancer Driver No 131 0.175 144 25 0.174 26
TAF1B TAF1B Q53T94 TATA box-binding protein-associated factor RNA polymerase I subunit B chr2 GO:0001067 Not Cancer Driver No 61 0.104 54 7 0.13 0
TAF1C TAF1C Q15572 TATA box-binding protein-associated factor RNA polymerase I subunit C chr16 GO:0001067 Not Cancer Driver No 114 0.131 312 35 0.112 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0001067 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0001067 Census Yes 54 0.163 305 53 0.174 0
TBP TBP P20226 TATA-box-binding protein chr6 GO:0001067 Not Cancer Driver No 40 0.118 164 14 0.085 0
TBPL1 TBPL1 P62380 TATA box-binding protein-like 1 chr6 GO:0001067 Not Cancer Driver No 27 0.145 6 0 0.0 0
TCF12_ENST00000267811 TCF12 Q99081 Transcription factor 12 chr15 GO:0001067 Census Yes 105 0.154 680 105 0.154 3
TCF15 TCF15 Q12870 Transcription factor 15 chr20 GO:0001067 Not Cancer Driver No 19 0.095 134 4 0.03 0
TCF21 TCF21 O43680 Transcription factor 21 chr6 GO:0001067 Not Cancer Driver No 55 0.307 120 40 0.333 0
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 GO:0001067 Census Yes 52 0.08 649 52 0.08 0
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 GO:0001067 Compendium Yes 141 0.211 662 136 0.205 13
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 GO:0001067 Not Cancer Driver No 25 0.102 110 15 0.136 1
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0001067 Compendium Yes 61 0.18 285 52 0.182 0
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 GO:0001067 Census, Compendium Yes 120 0.114 537 61 0.114 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0001067 Not Cancer Driver No 23 0.114 132 11 0.083 7
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 GO:0001067 Not Cancer Driver No 100 0.131 567 77 0.136 1
VAX1 VAX1 Q5SQQ9 Ventral anterior homeobox 1 chr10 GO:0001067 Not Cancer Driver No 36 0.108 234 25 0.107 1
VAX2 VAX2 Q9UIW0 Ventral anterior homeobox 2 chr2 GO:0001067 Not Cancer Driver No 34 0.117 210 22 0.105 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0001067 Not Cancer Driver No 64 0.15 102 16 0.157 14
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 GO:0001067 Not Cancer Driver No 129 0.136 427 63 0.148 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0001067 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0001067 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZNF350 ZNF350 Q9GZX5 Zinc finger protein 350 chr19 GO:0001067 Not Cancer Driver No 86 0.162 95 18 0.189 0
ZNF536 ZNF536 O15090 Zinc finger protein 536 chr19 GO:0001067 Not Cancer Driver No 596 0.458 991 445 0.449 0