Total number of protein in "GO:0001046" GO term: 43
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AGO1 | AGO1 | Q9UL18 | Protein argonaute-1 | chr1 | GO:0001046 | Not Cancer Driver | No | 126 | 0.147 | 87 | 11 | 0.126 | 0 |
AGO2 | AGO2 | Q9UKV8 | Protein argonaute-2 | chr8 | GO:0001046 | Not Cancer Driver | No | 126 | 0.147 | 141 | 15 | 0.106 | 11 |
BAZ2A | BAZ2A | Q9UIF9 | Bromodomain adjacent to zinc finger domain protein 2A | chr12 | GO:0001046 | Not Cancer Driver | No | 186 | 0.098 | 1283 | 118 | 0.092 | 0 |
CEBPB | CEBPB | P17676 | CCAAT/enhancer-binding protein beta | chr20 | GO:0001046 | Not Cancer Driver | No | 3 | 0.009 | 276 | 2 | 0.007 | 0 |
DR1_ENST00000370267 | DR1 | Q01658 | Protein Dr1 | chr1 | GO:0001046 | Not Cancer Driver | No | 21 | 0.119 | 84 | 12 | 0.143 | 0 |
DRAP1 | DRAP1 | Q14919 | Dr1-associated corepressor | chr11 | GO:0001046 | Not Cancer Driver | No | 28 | 0.137 | 170 | 22 | 0.129 | 0 |
EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:0001046 | Census, Compendium | Yes | 120 | 0.161 | 284 | 44 | 0.155 | 11 |
FOS | FOS | P01100 | Protein c-Fos | chr14 | GO:0001046 | Not Cancer Driver | No | 45 | 0.118 | 245 | 33 | 0.135 | 0 |
FOXP1_ENST00000318789 | FOXP1 | Q9H334 | Forkhead box protein P1 | chr3 | GO:0001046 | Census, Compendium | Yes | 109 | 0.161 | 448 | 71 | 0.158 | 3 |
GBX2 | GBX2 | P52951 | Homeobox protein GBX-2 | chr2 | GO:0001046 | Not Cancer Driver | No | 43 | 0.124 | 243 | 31 | 0.128 | 0 |
GTF2A1 | GTF2A1 | P52655 | Transcription initiation factor IIA subunit 1 | chr14 | GO:0001046 | Not Cancer Driver | No | 49 | 0.13 | 260 | 38 | 0.146 | 0 |
GTF2B | GTF2B | Q00403 | Transcription initiation factor IIB | chr1 | GO:0001046 | Not Cancer Driver | No | 33 | 0.104 | 80 | 6 | 0.075 | 0 |
H2AFY | MACROH2A1 | O75367 | Core histone macro-H2A.1 | chr5 | GO:0001046 | Not Cancer Driver | No | 46 | 0.124 | 125 | 19 | 0.152 | 0 |
H2AFZ | H2AZ1 | P0C0S5 | Histone H2A.Z | chr4 | GO:0001046 | Not Cancer Driver | No | 23 | 0.18 | 71 | 16 | 0.225 | 0 |
H3F3A_ENST00000366816 | H3-3B | P84243 | Histone H3.3 | chr1 | GO:0001046 | Not Cancer Driver | No | 32 | 0.235 | 51 | 22 | 0.431 | 3 |
H3F3B_ENST00000589599 | H3-3B | P84243 | Histone H3.3 | chr17 | GO:0001046 | Not Cancer Driver | No | 28 | 0.206 | 51 | 14 | 0.275 | 3 |
HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | GO:0001046 | Not Cancer Driver | No | 47 | 0.098 | 135 | 10 | 0.074 | 0 |
KLF10 | KLF10 | Q13118 | Krueppel-like factor 10 | chr8 | GO:0001046 | Not Cancer Driver | No | 59 | 0.123 | 349 | 46 | 0.132 | 0 |
MMP12 | MMP12 | P39900 | Macrophage metalloelastase | chr11 | GO:0001046 | Not Cancer Driver | No | 100 | 0.213 | 29 | 5 | 0.172 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0001046 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
NPM1 | NPM1 | P06748 | Nucleophosmin | chr5 | GO:0001046 | Census, Compendium | Yes | 29 | 0.099 | 249 | 22 | 0.088 | 0 |
NR3C1_ENST00000343796 | NR3C1 | P04150 | Glucocorticoid receptor | chr5 | GO:0001046 | Not Cancer Driver | No | 92 | 0.118 | 362 | 37 | 0.102 | 12 |
PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0001046 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
PAX6_ENST00000241001 | PAX6 | P26367 | Paired box protein Pax-6 | chr11 | GO:0001046 | Not Cancer Driver | No | 72 | 0.171 | 337 | 56 | 0.166 | 38 |
PIH1D1 | PIH1D1 | Q9NWS0 | PIH1 domain-containing protein 1 | chr19 | GO:0001046 | Not Cancer Driver | No | 30 | 0.103 | 157 | 13 | 0.083 | 0 |
POU2F1_ENST00000541643 | POU2F1 | P14859 | POU domain, class 2, transcription factor 1 | chr1 | GO:0001046 | Not Cancer Driver | No | 95 | 0.128 | 433 | 50 | 0.115 | 0 |
RELA | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0001046 | Compendium | Yes | 75 | 0.136 | 400 | 48 | 0.12 | 0 |
REST | REST | Q13127 | RE1-silencing transcription factor | chr4 | GO:0001046 | Not Cancer Driver | No | 142 | 0.129 | 868 | 113 | 0.13 | 4 |
RRN3 | RRN3 | Q9NYV6 | RNA polymerase I-specific transcription initiation factor RRN3 | chr16 | GO:0001046 | Not Cancer Driver | No | 66 | 0.101 | 115 | 15 | 0.13 | 0 |
RUVBL2 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | GO:0001046 | Not Cancer Driver | No | 62 | 0.134 | 100 | 13 | 0.13 | 0 |
SMARCA4 | SMARCA4 | P51532 | Transcription activator BRG1 | chr19 | GO:0001046 | Census, Compendium | Yes | 349 | 0.212 | 1072 | 195 | 0.182 | 5 |
SMARCB1_ENST00000644036 | SMARCB1 | Q12824 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | chr22 | GO:0001046 | Census, Compendium | Yes | 64 | 0.166 | 141 | 35 | 0.248 | 3 |
SNAPC3_ENST00000610884 | SNAPC3 | Q92966 | snRNA-activating protein complex subunit 3 | chr9 | GO:0001046 | Not Cancer Driver | No | 30 | 0.073 | 99 | 2 | 0.02 | 0 |
STAT1 | STAT1 | P42224 | Signal transducer and activator of transcription 1-alpha/beta | chr2 | GO:0001046 | Not Cancer Driver | No | 131 | 0.175 | 144 | 25 | 0.174 | 26 |
TAF1B | TAF1B | Q53T94 | TATA box-binding protein-associated factor RNA polymerase I subunit B | chr2 | GO:0001046 | Not Cancer Driver | No | 61 | 0.104 | 54 | 7 | 0.13 | 0 |
TAF1C | TAF1C | Q15572 | TATA box-binding protein-associated factor RNA polymerase I subunit C | chr16 | GO:0001046 | Not Cancer Driver | No | 114 | 0.131 | 312 | 35 | 0.112 | 0 |
TAF1_ENST00000373790 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:0001046 | Not Cancer Driver | No | 379 | 0.202 | 1152 | 219 | 0.19 | 5 |
TAF4 | TAF4 | O00268 | Transcription initiation factor TFIID subunit 4 | chr20 | GO:0001046 | Not Cancer Driver | No | 112 | 0.103 | 975 | 96 | 0.098 | 0 |
TBP | TBP | P20226 | TATA-box-binding protein | chr6 | GO:0001046 | Not Cancer Driver | No | 40 | 0.118 | 164 | 14 | 0.085 | 0 |
TBPL1 | TBPL1 | P62380 | TATA box-binding protein-like 1 | chr6 | GO:0001046 | Not Cancer Driver | No | 27 | 0.145 | 6 | 0 | 0.0 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0001046 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
UBTF | UBTF | P17480 | Nucleolar transcription factor 1 | chr17 | GO:0001046 | Not Cancer Driver | No | 100 | 0.131 | 567 | 77 | 0.136 | 1 |
ZBTB17_ENST00000375743 | ZBTB17 | Q13105 | Zinc finger and BTB domain-containing protein 17 | chr1 | GO:0001046 | Not Cancer Driver | No | 77 | 0.096 | 310 | 30 | 0.097 | 0 |