Total number of protein in "GO:0000281" GO term: 50
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ANK3 | ANK3 | Q12955 | Ankyrin-3 | chr10 | GO:0000281 | Not Cancer Driver | No | 860 | 0.196 | 3054 | 579 | 0.19 | 0 |
ANLN | ANLN | Q9NQW6 | Anillin | chr7 | GO:0000281 | Not Cancer Driver | No | 144 | 0.128 | 767 | 104 | 0.136 | 2 |
APC | APC | P25054 | Adenomatous polyposis coli protein | chr5 | GO:0000281 | Census, Compendium | Yes | 412 | 0.145 | 2406 | 345 | 0.143 | 22 |
ARL3 | ARL3 | P36405 | ADP-ribosylation factor-like protein 3 | chr10 | GO:0000281 | Not Cancer Driver | No | 16 | 0.088 | 0 | 0 | 0.0 | 2 |
BBS4 | BBS4 | Q96RK4 | Bardet-Biedl syndrome 4 protein | chr15 | GO:0000281 | Not Cancer Driver | No | 58 | 0.112 | 110 | 16 | 0.145 | 9 |
CENPA | CENPA | P49450 | Histone H3-like centromeric protein A | chr2 | GO:0000281 | Not Cancer Driver | No | 15 | 0.107 | 50 | 4 | 0.08 | 0 |
CEP55 | CEP55 | Q53EZ4 | Centrosomal protein of 55 kDa | chr10 | GO:0000281 | Not Cancer Driver | No | 59 | 0.127 | 264 | 26 | 0.098 | 0 |
CHMP4B | CHMP4B | Q9H444 | Charged multivesicular body protein 4b | chr20 | GO:0000281 | Not Cancer Driver | No | 25 | 0.112 | 201 | 22 | 0.109 | 2 |
CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | GO:0000281 | Not Cancer Driver | No | 284 | 0.14 | 1017 | 160 | 0.157 | 3 |
CKAP2 | CKAP2 | Q8WWK9 | Cytoskeleton-associated protein 2 | chr13 | GO:0000281 | Not Cancer Driver | No | 72 | 0.105 | 522 | 57 | 0.109 | 0 |
CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | GO:0000281 | Not Cancer Driver | No | 188 | 0.111 | 372 | 41 | 0.11 | 3 |
ECT2 | ECT2 | Q9H8V3 | Protein ECT2 | chr3 | GO:0000281 | Not Cancer Driver | No | 104 | 0.114 | 284 | 33 | 0.116 | 0 |
EFHC1 | EFHC1 | Q5JVL4 | EF-hand domain-containing protein 1 | chr6 | GO:0000281 | Not Cancer Driver | No | 79 | 0.123 | 78 | 15 | 0.192 | 17 |
EFHC2 | EFHC2 | Q5JST6 | EF-hand domain-containing family member C2 | chrX | GO:0000281 | Not Cancer Driver | No | 113 | 0.151 | 50 | 10 | 0.2 | 0 |
ESPL1 | ESPL1 | Q14674 | Separin | chr12 | GO:0000281 | Not Cancer Driver | No | 211 | 0.1 | 380 | 39 | 0.103 | 0 |
INCENP | INCENP | Q9NQS7 | Inner centromere protein | chr11 | GO:0000281 | Not Cancer Driver | No | 107 | 0.117 | 856 | 103 | 0.12 | 0 |
JTB | JTB | O76095 | Protein JTB | chr1 | GO:0000281 | Not Cancer Driver | No | 14 | 0.096 | 4 | 1 | 0.25 | 0 |
KIF20A | KIF20A | O95235 | Kinesin-like protein KIF20A | chr5 | GO:0000281 | Not Cancer Driver | No | 79 | 0.089 | 340 | 40 | 0.118 | 1 |
KIF23 | KIF23 | Q02241 | Kinesin-like protein KIF23 | chr15 | GO:0000281 | Not Cancer Driver | No | 102 | 0.106 | 559 | 62 | 0.111 | 0 |
KIF4A | KIF4A | O95239 | Chromosome-associated kinesin KIF4A | chrX | GO:0000281 | Not Cancer Driver | No | 188 | 0.153 | 674 | 116 | 0.172 | 0 |
KIF4B | KIF4B | Q2VIQ3 | Chromosome-associated kinesin KIF4B | chr5 | GO:0000281 | Not Cancer Driver | No | 303 | 0.246 | 571 | 150 | 0.263 | 0 |
LZTS2 | LZTS2 | Q9BRK4 | Leucine zipper putative tumor suppressor 2 | chr10 | GO:0000281 | Not Cancer Driver | No | 78 | 0.117 | 508 | 66 | 0.13 | 0 |
MAP9 | MAP9 | Q49MG5 | Microtubule-associated protein 9 | chr4 | GO:0000281 | Not Cancer Driver | No | 118 | 0.182 | 622 | 116 | 0.186 | 0 |
MITD1 | MITD1 | Q8WV92 | MIT domain-containing protein 1 | chr2 | GO:0000281 | Not Cancer Driver | No | 31 | 0.124 | 45 | 8 | 0.178 | 0 |
MYH10_ENST00000269243 | MYH10 | P35580 | Myosin-10 | chr17 | GO:0000281 | Not Cancer Driver | No | 258 | 0.131 | 1134 | 136 | 0.12 | 0 |
NUSAP1 | NUSAP1 | Q9BXS6 | Nucleolar and spindle-associated protein 1 | chr15 | GO:0000281 | Not Cancer Driver | No | 49 | 0.111 | 415 | 42 | 0.101 | 0 |
PDCD6IP_ENST00000307296 | PDCD6IP | Q8WUM4 | Programmed cell death 6-interacting protein | chr3 | GO:0000281 | Not Cancer Driver | No | 85 | 0.098 | 272 | 22 | 0.081 | 0 |
PLK1 | PLK1 | P53350 | Serine/threonine-protein kinase PLK1 | chr16 | GO:0000281 | Not Cancer Driver | No | 87 | 0.144 | 119 | 13 | 0.109 | 0 |
RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | GO:0000281 | Not Cancer Driver | No | 25 | 0.124 | 25 | 2 | 0.08 | 0 |
RACGAP1_ENST00000454520 | RACGAP1 | Q9H0H5 | Rac GTPase-activating protein 1 | chr12 | GO:0000281 | Not Cancer Driver | No | 74 | 0.117 | 255 | 27 | 0.106 | 0 |
RASA1 | RASA1 | P20936 | Ras GTPase-activating protein 1 | chr5 | GO:0000281 | Compendium | Yes | 154 | 0.147 | 181 | 25 | 0.138 | 3 |
RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | GO:0000281 | Not Cancer Driver | No | 52 | 0.265 | 19 | 2 | 0.105 | 0 |
RHOC_ENST00000369642 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | GO:0000281 | Not Cancer Driver | No | 30 | 0.155 | 53 | 7 | 0.132 | 0 |
ROCK1 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0000281 | Not Cancer Driver | No | 184 | 0.136 | 780 | 103 | 0.132 | 0 |
ROCK2 | ROCK2 | O75116 | Rho-associated protein kinase 2 | chr2 | GO:0000281 | Not Cancer Driver | No | 145 | 0.104 | 732 | 81 | 0.111 | 0 |
RTKN | RTKN | Q9BST9 | Rhotekin | chr2 | GO:0000281 | Not Cancer Driver | No | 67 | 0.119 | 265 | 35 | 0.132 | 0 |
SEPT6 | SEPTIN6 | Q14141 | Septin-6 | chrX | GO:0000281 | Not Cancer Driver | No | 69 | 0.159 | 161 | 25 | 0.155 | 0 |
SNX18 | SNX18 | Q96RF0 | Sorting nexin-18 | chr5 | GO:0000281 | Not Cancer Driver | No | 54 | 0.086 | 236 | 7 | 0.03 | 0 |
SNX33 | SNX33 | Q8WV41 | Sorting nexin-33 | chr15 | GO:0000281 | Not Cancer Driver | No | 63 | 0.11 | 204 | 18 | 0.088 | 0 |
SNX9 | SNX9 | Q9Y5X1 | Sorting nexin-9 | chr6 | GO:0000281 | Not Cancer Driver | No | 71 | 0.119 | 231 | 23 | 0.1 | 0 |
SON | SON | P18583 | Protein SON | chr21 | GO:0000281 | Not Cancer Driver | No | 234 | 0.096 | 2109 | 212 | 0.101 | 0 |
SPAST | SPAST | Q9UBP0 | Spastin | chr2 | GO:0000281 | Not Cancer Driver | No | 73 | 0.119 | 270 | 25 | 0.093 | 77 |
SPTBN1 | SPTBN1 | Q01082 | Spectrin beta chain, non-erythrocytic 1 | chr2 | GO:0000281 | Not Cancer Driver | No | 311 | 0.132 | 869 | 123 | 0.142 | 0 |
STAMBP_ENST00000339566 | STAMBP | O95630 | STAM-binding protein | chr2 | GO:0000281 | Not Cancer Driver | No | 51 | 0.12 | 139 | 16 | 0.115 | 6 |
STMN1_ENST00000357865 | STMN1 | P16949 | Stathmin | chr1 | GO:0000281 | Not Cancer Driver | No | 15 | 0.101 | 149 | 15 | 0.101 | 0 |
TRIM36 | TRIM36 | Q9NQ86 | E3 ubiquitin-protein ligase TRIM36 | chr5 | GO:0000281 | Not Cancer Driver | No | 106 | 0.146 | 89 | 21 | 0.236 | 1 |
TTC19 | TTC19 | Q6DKK2 | Tetratricopeptide repeat protein 19, mitochondrial | chr17 | GO:0000281 | Not Cancer Driver | No | 34 | 0.089 | 76 | 3 | 0.039 | 0 |
UNC119 | UNC119 | Q13432 | Protein unc-119 homolog A | chr17 | GO:0000281 | Not Cancer Driver | No | 20 | 0.083 | 89 | 4 | 0.045 | 1 |
USP8 | USP8 | P40818 | Ubiquitin carboxyl-terminal hydrolase 8 | chr15 | GO:0000281 | Census, Compendium | Yes | 122 | 0.109 | 602 | 69 | 0.115 | 0 |
ZFYVE26 | ZFYVE26 | Q68DK2 | Zinc finger FYVE domain-containing protein 26 | chr14 | GO:0000281 | Not Cancer Driver | No | 307 | 0.121 | 561 | 71 | 0.127 | 0 |