GO term |
GO name |
GO namespace |
GO def |
GO:0050796 | regulation of insulin secretion | biological_process | Any process that modulates the frequency, rate or extent of the regulated release of insulin. [GOC:ai] |
GO:0019888 | protein phosphatase regulator activity | molecular_function | Binds to and modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule. [GOC:ai] |
GO:0051301 | cell division | biological_process | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. [GOC:di, GOC:go_curators, GOC:pr] |
GO:0005488 | binding | molecular_function | The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. [GOC:ceb, GOC:mah, ISBN:0198506732] |
GO:0019899 | enzyme binding | molecular_function | Binding to an enzyme, a protein with catalytic activity. [GOC:jl] |
GO:0000086 | G2/M transition of mitotic cell cycle | biological_process | The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex. [GOC:mtg_cell_cycle] |
GO:0005737 | cytoplasm | cellular_component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
GO:0098772 | molecular function regulator | molecular_function | A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition. [GOC:dos, GOC:pt] |
GO:0000278 | mitotic cell cycle | biological_process | Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. [GOC:mah, ISBN:0815316194, Reactome:69278] |
GO:0016247 | channel regulator activity | molecular_function | Bonds to and modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. [GOC:mah] |
GO:0019903 | protein phosphatase binding | molecular_function | Binding to a protein phosphatase. [GOC:jl] |
GO:0035308 | negative regulation of protein dephosphorylation | biological_process | Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein. [GOC:bf] |
GO:0005654 | nucleoplasm | cellular_component | That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653] |
GO:0007584 | response to nutrient | biological_process | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus. [GOC:go_curators] |
GO:0099106 | ion channel regulator activity | molecular_function | Modulates the activity of a channel via direct interaction with it. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. [GOC:dos] |
GO:0005102 | signaling receptor binding | molecular_function | Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [GOC:bf, GOC:ceb, ISBN:0198506732] |
GO:0043086 | negative regulation of catalytic activity | biological_process | Any process that stops or reduces the activity of an enzyme. [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] |
GO:0015459 | potassium channel regulator activity | molecular_function | Binds to and modulates the activity of a potassium channel. [GOC:dos, GOC:mah] |
GO:0004864 | protein phosphatase inhibitor activity | molecular_function | Binds to and stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins. [GOC:ai] |
GO:0019902 | phosphatase binding | molecular_function | Binding to a phosphatase. [GOC:jl] |
GO:0005515 | protein binding | molecular_function | Binding to a protein. [GOC:go_curators] |
GO:0019212 | phosphatase inhibitor activity | molecular_function | Binds to and stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule. [GOC:ai] |
GO term |
GO name |
GO namespace |
GO def |