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ATP8B2 ,ATP8B2 ,P98198
  • Uniprot Accession= P98198
  • Ensembl Transcript= ENST00000368489.3
  • Uniprot Name= ATP8B2
  • Name= Phospholipid-transporting ATPase ID
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 18
GO term
GO name
GO namespace
GO def
GO:0140326 ATPase-coupled intramembrane lipid transporter activity molecular_function Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases. [PMID:16828084]
GO:0008525 phosphatidylcholine transporter activity molecular_function Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. [GOC:ai, ISBN:0198506732]
GO:0005548 phospholipid transporter activity molecular_function Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester. [GOC:ai, ISBN:0198506732]
GO:0005319 lipid transporter activity molecular_function Enables the directed movement of lipids into, out of or within a cell, or between cells. [GOC:ai]
GO:0034220 ion transmembrane transport biological_process A process in which an ion is transported across a membrane. [GOC:mah]
GO:0005215 transporter activity molecular_function Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells. [GOC:ai, GOC:dgf]
GO:0007030 Golgi organization biological_process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. [GOC:dph, GOC:jl, GOC:mah]
GO:0005789 endoplasmic reticulum membrane cellular_component The lipid bilayer surrounding the endoplasmic reticulum. [GOC:mah]
GO:1990351 transporter complex cellular_component A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells. [GOC:bhm, PMID:15449578]
GO:0032991 protein-containing complex cellular_component A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. [GOC:dos, GOC:mah]
GO:0045332 phospholipid translocation biological_process The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. [ISBN:0815316194, PMID:16452632, PMID:20043909, PMID:20302864]
GO:0005886 plasma membrane cellular_component The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
GO:0005794 Golgi apparatus cellular_component A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. [ISBN:0198506732]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0005802 trans-Golgi network cellular_component The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. [GOC:vw, ISBN:0815316194]
GO:0005524 ATP binding molecular_function Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732]
GO:0005887 integral component of plasma membrane cellular_component The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. [GOC:dos, GOC:go_curators]
GO:0000287 magnesium ion binding molecular_function Binding to a magnesium (Mg) ion. [GOC:ai]