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ZMPSTE24 ,ZMPSTE24 ,O75844
  • Number of Interaction partner in intact: 20
  • Number of Interaction partner in biogrid: 97
  • Number of Interaction partner in hippie: 126
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABHD14A_ENST00000491470 ABHD14A C9IYJ8 Protein ABHD14A chr3 Not Cancer Driver No 1 hippie, biogrid 8 0 0 0 0
ADCK5 ADCK5 Q3MIX3 Uncharacterized aarF domain-containing protein kinase 5 chr8 Not Cancer Driver No 1 hippie, biogrid 51 5 2 2 0
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
AMPD2_ENST00000528667 AMPD2 Q01433 AMP deaminase 2 chr1 Not Cancer Driver No 1 hippie, biogrid 93 275 27 27 3
APOC3 APOC3 P02656 Apolipoprotein C-III chr11 Not Cancer Driver No 1 hippie, biogrid 14 12 2 2 1
ARMCX3_ENST00000537169 ARMCX3 Q9UH62 Armadillo repeat-containing X-linked protein 3 chrX Not Cancer Driver No 1 hippie, biogrid 39 77 7 7 0
ATG2A ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 Not Cancer Driver No 1 intact, hippie 228 887 124 124 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 157 80 11 11 1
ATP6V1H_ENST00000396774 ATP6V1H Q9UI12 V-type proton ATPase subunit H chr8 Not Cancer Driver No 1 hippie, biogrid 76 35 2 2 0
B3GAT1_ENST00000312527 B3GAT1 Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 85 93 32 32 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie, biogrid 37 104 14 14 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie, biogrid 37 19 0 0 0
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 Not Cancer Driver No 1 hippie, biogrid 45 128 13 13 1
CDX1 CDX1 P47902 Homeobox protein CDX-1 chr5 Not Cancer Driver No 1 intact, hippie 21 241 13 13 0
CENPH CENPH Q9H3R5 Centromere protein H chr5 Not Cancer Driver No 1 hippie, biogrid 28 85 7 7 0
CENPM CENPM Q9NSP4 Centromere protein M chr22 Not Cancer Driver No 1 hippie, biogrid 12 1 0 0 0
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie, biogrid 190 71 6 6 1
COPZ2 COPZ2 Q9P299 Coatomer subunit zeta-2 chr17 Not Cancer Driver No 1 hippie, biogrid 15 39 0 0 0
COX8A COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CYB5R3_ENST00000352397 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie, biogrid 42 24 3 3 9
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 81 17 2 2 0
CYP2C9 CYP2C9 P11712 Cytochrome P450 2C9 chr10 Not Cancer Driver No 1 hippie, biogrid 122 36 14 14 0
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 hippie, biogrid 34 13 3 3 1
DNAL4 DNAL4 O96015 Dynein axonemal light chain 4 chr22 Not Cancer Driver No 1 hippie, biogrid 9 15 4 4 0
DUSP23_ENST00000368109 DUSP23 Q9BVJ7 Dual specificity protein phosphatase 23 chr1 Not Cancer Driver No 1 hippie, biogrid 6 13 1 1 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 107 59 6 6 2
EMC2 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 hippie 48 29 3 3 0
EMC4 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 1 hippie 15 17 2 2 0
EMD EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 42 160 28 28 4
FAM118B FAM118B Q9BPY3 Protein FAM118B chr11 Not Cancer Driver No 1 hippie, biogrid 50 37 4 4 0
FAM20C FAM20C Q8IXL6 Extracellular serine/threonine protein kinase FAM20C chr7 Not Cancer Driver No 1 hippie 33 188 3 3 9
FDPS_ENST00000368356 FDPS P14324 Farnesyl pyrophosphate synthase chr1 Not Cancer Driver No 2 hippie, biogrid 66 0 0 0 1
FGF12 FGF12 P61328 Fibroblast growth factor 12 chr3 Not Cancer Driver No 1 hippie, biogrid 74 102 30 30 1
FTSJ1 FTSJ1 Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase chrX Not Cancer Driver No 1 intact, hippie 44 89 14 14 0
GALNT2 GALNT2 Q10471 Polypeptide N-acetylgalactosaminyltransferase 2 chr1 Not Cancer Driver No 1 hippie, biogrid 94 122 22 22 2
GDPD5_ENST00000529721 GDPD5 Q8WTR4 Glycerophosphodiester phosphodiesterase domain-containing protein 5 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 74 65 11 11 0
GJB7 GJB7 Q6PEY0 Gap junction beta-7 protein chr6 Not Cancer Driver No 1 intact, hippie, biogrid 30 0 0 0 0
GJD3 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 5 79 0 0 0
GPR21 GPR21 Q99679 Probable G-protein coupled receptor 21 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 39 2 0 0 0
GSX1 GSX1 Q9H4S2 GS homeobox 1 chr13 Not Cancer Driver No 1 hippie, biogrid 26 137 14 14 0
GTF2E2 GTF2E2 P29084 Transcription initiation factor IIE subunit beta chr8 Not Cancer Driver No 1 intact, hippie, biogrid 34 130 16 16 2
HADHB HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 71 41 9 9 14
HIST1H1B H1-5 P16401 Histone H1.5 chr6 Not Cancer Driver No 1 intact 66 224 66 66 0
HK1_ENST00000359426 HK1 P19367 Hexokinase-1 chr10 Not Cancer Driver No 1 hippie, biogrid 127 75 16 16 6
HNRNPF_ENST00000356053 HNRNPF P52597 Heterogeneous nuclear ribonucleoprotein F chr10 Not Cancer Driver No 1 hippie, biogrid 65 105 18 18 0
HNRNPUL1 HNRNPUL1 Q9BUJ2 Heterogeneous nuclear ribonucleoprotein U-like protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 100 535 49 49 0
HSD17B11 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 28 3 0 0 0
HSD3B7 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 43 27 5 5 2
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie, biogrid 155 419 90 90 0
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
IL19_ENST00000270218 IL19 Q9UHD0 Interleukin-19 chr1 Not Cancer Driver No 1 hippie, biogrid 16 0 0 0 0
IL7 IL7 P13232 Interleukin-7 chr8 Not Cancer Driver No 1 hippie, biogrid 29 19 4 4 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 Not Cancer Driver No 1 hippie, biogrid 96 82 16 16 5
KCNMB3 KCNMB3 Q9NPA1 Calcium-activated potassium channel subunit beta-3 chr3 Not Cancer Driver No 1 hippie, biogrid 27 22 2 2 0
KIAA2013_ENST00000616327 KIAA2013 Q8IYS2 Uncharacterized protein KIAA2013 chr1 Not Cancer Driver No 1 hippie, biogrid 35 78 5 5 0
KLF16 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 intact, hippie 13 204 8 8 0
KRTAP19-4 KRTAP19-4 Q3LI73 Keratin-associated protein 19-4 chr21 Not Cancer Driver No 1 hippie, biogrid 25 0 0 0 0
KRTAP19-7 KRTAP19-7 Q3SYF9 Keratin-associated protein 19-7 chr21 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
KRTAP6-1 KRTAP6-1 Q3LI64 Keratin-associated protein 6-1 chr21 Not Cancer Driver No 1 hippie, biogrid 27 0 0 0 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LNPK_ENST00000272748 LNPK Q9C0E8 Endoplasmic reticulum junction formation protein lunapark chr2 Not Cancer Driver No 1 hippie 62 257 43 43 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MED21 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 2 hippie, biogrid 12 46 3 3 0
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 hippie, biogrid 17 0 0 0 0
MME_ENST00000492661 MME P08473 Neprilysin chr3 Not Cancer Driver No 1 intact, hippie 189 40 17 17 4
MORF4L1 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 43 163 17 17 0
MRPL40 MRPL40 Q9NQ50 39S ribosomal protein L40, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 20 104 9 9 0
MRPS5 MRPS5 P82675 28S ribosomal protein S5, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 52 157 20 20 0
MS4A15 MS4A15 Q8N5U1 Membrane-spanning 4-domains subfamily A member 15 chr11 Not Cancer Driver No 1 hippie, biogrid 41 27 6 6 0
MYLK4 MYLK4 Q86YV6 Myosin light chain kinase family member 4 chr6 Not Cancer Driver No 1 hippie, biogrid 67 77 14 14 0
MYO1B MYO1B O43795 Unconventional myosin-Ib chr2 Not Cancer Driver No 1 hippie, biogrid 144 34 4 4 0
NDUFB7 NDUFB7 P17568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 chr19 Not Cancer Driver No 1 hippie, biogrid 17 65 6 6 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NRM NRM Q8IXM6 Nurim chr6 Not Cancer Driver No 1 hippie, biogrid 19 1 0 0 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie, biogrid 58 470 51 51 6
OR51V1 OR51V1 Q9H2C8 Olfactory receptor 51V1 chr11 Not Cancer Driver No 1 hippie, biogrid 116 0 0 0 0
OTULINL OTULINL Q9NUU6 Inactive ubiquitin thioesterase OTULINL chr5 Not Cancer Driver No 1 hippie 59 21 0 0 0
PDIA4 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie, biogrid 81 147 22 22 0
PDLIM5_ENST00000317968 PDLIM5 Q96HC4 PDZ and LIM domain protein 5 chr4 Not Cancer Driver No 1 hippie, biogrid 89 372 57 57 0
PKMYT1 PKMYT1 Q99640 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase chr16 Not Cancer Driver No 1 hippie, biogrid 39 228 19 19 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 Not Cancer Driver No 1 hippie 2 23 1 1 0
PMF1-BGLAP_ENST00000320139 PMF1-BGLAP Q6P1K2-3 Isoform 3 of Polyamine-modulated factor 1 chr1 Not Cancer Driver No 1 biogrid 12 70 0 0 0
PMF1_ENST00000368277 PMF1 Q6P1K2 Polyamine-modulated factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 20 76 6 6 0
PRELID1 PRELID1 Q9Y255 PRELI domain-containing protein 1, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 21 44 2 2 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie, biogrid 49 140 25 25 0
RAB10 RAB10 P61026 Ras-related protein Rab-10 chr2 Not Cancer Driver No 1 hippie, biogrid 19 28 2 2 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 24 50 4 4 0
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 Not Cancer Driver No 1 hippie 202 578 75 75 0
RNF26 RNF26 Q9BY78 E3 ubiquitin-protein ligase RNF26 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 44 71 7 7 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RPL35A RPL35A P18077 60S ribosomal protein L35a chr3 Not Cancer Driver No 1 hippie, biogrid 9 25 0 0 1
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 50 69 3 3 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 53 26 4 4 0
S100A10 S100A10 P60903 Protein S100-A10 chr1 Not Cancer Driver No 1 hippie, biogrid 11 3 1 1 0
SEC61B SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 2 hippie, biogrid 11 60 7 7 0
SEC62 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 41 211 23 23 0
SLC17A2_ENST00000265425 SLC17A2 O00624 Sodium-dependent phosphate transport protein 3 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 81 12 5 5 0
SLC18A1_ENST00000276373 SLC18A1 P54219 Chromaffin granule amine transporter chr8 Not Cancer Driver No 2 intact, hippie, biogrid 98 28 4 4 0
SLC2A5 SLC2A5 P22732 Solute carrier family 2, facilitated glucose transporter member 5 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 73 12 4 4 0
SLC39A3 SLC39A3 Q9BRY0 Zinc transporter ZIP3 chr19 Not Cancer Driver No 1 hippie, biogrid 41 0 0 0 0
SPATA48 SPATA48 A4D263 Spermatogenesis-associated protein 48 chr7 Not Cancer Driver No 1 intact, hippie 36 282 20 20 0
SRGAP3 SRGAP3 O43295 SLIT-ROBO Rho GTPase-activating protein 3 chr3 Census, Compendium Yes 1 hippie, biogrid 195 549 97 97 0
ST7 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie 62 64 5 5 0
STX8 STX8 Q9UNK0 Syntaxin-8 chr17 Not Cancer Driver No 1 hippie, biogrid 32 98 10 10 0
SYNE3 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 143 236 42 42 0
SYNJ2BP SYNJ2BP P57105 Synaptojanin-2-binding protein chr14 Not Cancer Driver No 1 hippie, biogrid 27 12 4 4 0
SYT6_ENST00000610222 SYT6 Q5T7P8 Synaptotagmin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 98 137 18 18 0
TCTN2 TCTN2 Q96GX1 Tectonic-2 chr12 Not Cancer Driver No 1 intact, hippie 75 23 2 2 0
TCTN3 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 intact, hippie 45 71 8 8 1
TECTB TECTB Q96PL2 Beta-tectorin chr10 Not Cancer Driver No 1 hippie, biogrid 53 2 1 1 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 31 56 4 4 1
TMEM196 TMEM196 Q5HYL7 Transmembrane protein 196 chr7 Not Cancer Driver No 1 hippie, biogrid 36 12 1 1 0
TMEM43 TMEM43 Q9BTV4 Transmembrane protein 43 chr3 Not Cancer Driver No 1 hippie, biogrid 47 57 9 9 3
TMPRSS12 TMPRSS12 Q86WS5 Transmembrane protease serine 12 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 50 44 7 7 0
TNFRSF17 TNFRSF17 Q02223 Tumor necrosis factor receptor superfamily member 17 chr16 Census Yes 2 hippie, biogrid 28 1 0 0 0
TOMM6_ENST00000398881 TOMM6 Q96B49 Mitochondrial import receptor subunit TOM6 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 6 18 2 2 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
VAC14 VAC14 Q08AM6 Protein VAC14 homolog chr16 Not Cancer Driver No 2 hippie, biogrid 97 116 19 19 3
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 38 36 4 4 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WASHC3 WASHC3 Q9Y3C0 WASH complex subunit 3 chr12 Not Cancer Driver No 1 hippie 29 100 8 8 0
WIF1 WIF1 Q9Y5W5 Wnt inhibitory factor 1 chr12 Census Yes 1 hippie, biogrid 74 30 3 3 0