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ZFYVE9 ,ZFYVE9 ,O95405
  • Uniprot Accession= O95405
  • Ensembl Transcript= ENST00000287727.7
  • Uniprot Name= ZFYVE9
  • Name= Zinc finger FYVE domain-containing protein 9
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 32
  • Number of Interaction partner in biogrid: 38
  • Number of Interaction partner in hippie: 90
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX Not Cancer Driver No 1 hippie, biogrid 104 68 5 5 0
ANKFY1_ENST00000341657 ANKFY1 Q9P2R3 Rabankyrin-5 chr17 Not Cancer Driver No 1 hippie, biogrid 109 185 29 29 0
ANKLE2 ANKLE2 Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 chr12 Not Cancer Driver No 1 intact, hippie 127 521 71 71 2
ANPEP ANPEP P15144 Aminopeptidase N chr15 Not Cancer Driver No 1 hippie, biogrid 175 109 26 26 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
B3GAT1_ENST00000312527 B3GAT1 Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 85 93 32 32 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 Not Cancer Driver No 1 hippie 98 861 79 79 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 Not Cancer Driver No 2 intact, hippie 86 142 26 26 5
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
CHD6 CHD6 Q8TD26 Chromodomain-helicase-DNA-binding protein 6 chr20 Not Cancer Driver No 1 intact, hippie 393 1469 213 213 0
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie 190 71 6 6 1
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 Compendium Yes 1 hippie 383 151 42 42 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 Census Yes 1 intact 133 124 17 17 20
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 51 98 19 19 0
DAZAP2_ENST00000412716 DAZAP2 Q15038 DAZ-associated protein 2 chr12 Not Cancer Driver No 1 hippie 17 68 7 7 0
DEFA6 DEFA6 Q01524 Defensin-6 chr8 Not Cancer Driver No 2 hippie, biogrid 19 15 2 2 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 151 8 1 1 0
EEA1 EEA1 Q15075 Early endosome antigen 1 chr12 Not Cancer Driver No 2 intact, hippie 151 1168 126 126 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 Not Cancer Driver No 1 hippie 229 1079 153 153 2
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 Not Cancer Driver No 1 intact 182 140 24 24 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 Census, Compendium Yes 1 intact 280 71 15 15 0
ERBIN_ENST00000284037 ERBIN Q96RT1 Erbin chr5 Not Cancer Driver No 1 intact, hippie 167 967 118 118 0
ETS2 ETS2 P15036 Protein C-ets-2 chr21 Not Cancer Driver No 2 intact, hippie 73 127 25 25 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 intact 152 230 43 43 74
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 Census, Compendium Yes 1 intact 238 228 44 44 72
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 intact 113 162 28 28 0
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie 30 0 0 0 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 43 122 15 15 0
FOS FOS P01100 Protein c-Fos chr14 Not Cancer Driver No 1 hippie 45 245 33 33 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 86 110 26 26 50
GJD3 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 5 79 0 0 0
HERC2 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 Compendium Yes 1 hippie 718 971 150 150 1
HGS HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 Not Cancer Driver No 1 hippie 109 528 74 74 0
IFITM1_ENST00000528780 IFITM1 P13164 Interferon-induced transmembrane protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 19 0 0 0 0
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
JUP JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 2 intact, hippie 112 241 37 37 0
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 Not Cancer Driver No 1 hippie 103 49 11 11 12
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie, biogrid 788 7 2 2 27
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 47 93 10 10 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie, biogrid 43 55 7 7 1
LAMP3 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 67 222 38 38 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LRP12 LRP12 Q9Y561 Low-density lipoprotein receptor-related protein 12 chr8 Not Cancer Driver No 1 hippie 199 240 54 54 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 Not Cancer Driver No 1 hippie 176 342 41 41 3
NCKIPSD NCKIPSD Q9NZQ3 NCK-interacting protein with SH3 domain chr3 Census Yes 2 hippie, biogrid 63 260 28 28 0
NIT1 NIT1 Q86X76 Deaminated glutathione amidase chr1 Not Cancer Driver No 1 hippie 41 18 3 3 0
NUP155 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie 154 221 19 19 1
OCLN OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 54 244 21 21 1
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 Census, Compendium Yes 1 intact 290 173 45 45 2
PML PML P29590 Protein PML chr15 Census, Compendium Yes 2 intact, hippie 112 312 34 34 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 72 44 4 4 3
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 7 intact, hippie, biogrid 38 27 6 6 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 2 intact, hippie 47 25 5 5 5
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 8 intact, hippie, biogrid 26 23 4 4 0
PPP1R3A PPP1R3A Q16821 Protein phosphatase 1 regulatory subunit 3A chr7 Not Cancer Driver No 1 hippie 430 807 334 334 1
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 2 intact, hippie 179 0 0 0 4
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie, biogrid 31 43 4 4 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RAB4A RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 26 32 11 11 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 32 65 15 15 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 24 50 4 4 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 biogrid 27 11 0 0 4
RAB9A RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 2 intact, hippie, biogrid 18 21 1 1 0
RBBP6 RBBP6 Q7Z6E9 E3 ubiquitin-protein ligase RBBP6 chr16 Not Cancer Driver No 1 hippie 229 1626 212 212 0
RHO RHO P08100 Rhodopsin chr3 Not Cancer Driver No 1 intact, hippie 68 18 3 3 69
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie, biogrid 52 19 2 2 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RHOQ RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 Not Cancer Driver No 1 hippie 25 0 0 0 0
RHOT2 RHOT2 Q8IXI1 Mitochondrial Rho GTPase 2 chr16 Not Cancer Driver No 2 intact, hippie 52 79 5 5 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 19 54 4 4 0
RNF11 RNF11 Q9Y3C5 RING finger protein 11 chr1 Not Cancer Driver No 1 hippie 17 76 7 7 0
RNPEP RNPEP Q9H4A4 Aminopeptidase B chr1 Not Cancer Driver No 1 intact, hippie 60 86 4 4 0
SCYL2_ENST00000360820 SCYL2 Q6P3W7 SCY1-like protein 2 chr12 Not Cancer Driver No 1 hippie 103 328 29 29 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 Census, Compendium Yes 6 intact, hippie, biogrid 79 137 12 12 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 9 intact, hippie, biogrid 97 111 19 19 5
SPART_ENST00000355182 SPART Q8N0X7 Spartin chr13 Not Cancer Driver No 1 intact, hippie 112 396 68 68 1
ST7 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 intact, hippie 62 64 5 5 0
STAM2 STAM2 O75886 Signal transducing adapter molecule 2 chr2 Not Cancer Driver No 1 hippie 69 291 30 30 0
STX3 STX3 Q13277 Syntaxin-3 chr11 Not Cancer Driver No 1 intact, hippie 51 129 30 30 0
STX6 STX6 O43752 Syntaxin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 33 78 11 11 0
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 29 164 14 14 0
STYK1 STYK1 Q6J9G0 Tyrosine-protein kinase STYK1 chr12 Not Cancer Driver No 1 intact 83 35 10 10 0
SUMF2_ENST00000275607 SUMF2 Q8NBJ7-2 Isoform 2 of Inactive C-alpha-formylglycine-generating enzyme 2 chr7 Not Cancer Driver No 2 intact, hippie 27 75 12 12 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie 165 572 87 87 0
SVEP1 SVEP1 Q4LDE5 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 chr9 Not Cancer Driver No 1 hippie 626 229 33 33 0
TENT5A TENT5A Q96IP4 Terminal nucleotidyltransferase 5A chr6 Not Cancer Driver No 2 intact, hippie 43 0 0 0 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 1 hippie, biogrid 89 80 6 6 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 Not Cancer Driver No 1 hippie 86 23 3 3 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 Census, Compendium Yes 1 hippie 106 60 16 16 25
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 intact, hippie 51 399 46 46 0
TMPRSS11B TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 95 5 0 0 0
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 Not Cancer Driver No 1 hippie 46 159 23 23 0
UBXN11_ENST00000374221 UBXN11 Q5T124 UBX domain-containing protein 11 chr1 Not Cancer Driver No 1 hippie 74 335 54 54 0
VASP VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 1 hippie, biogrid 39 335 34 34 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
ZKSCAN1 ZKSCAN1 P17029 Zinc finger protein with KRAB and SCAN domains 1 chr7 Not Cancer Driver No 1 hippie 68 346 41 41 0
ZMYND8_ENST00000311275 ZMYND8 Q9ULU4 Protein kinase C-binding protein 1 chr20 Not Cancer Driver No 1 hippie 176 830 124 124 0