Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACTBL2 | ACTBL2 | Q562R1 | Beta-actin-like protein 2 | chr5 | Not Cancer Driver | No | 1 | intact | 73 | 29 | 5 | 5 | 0 |
ACTG1_ENST00000575087 | ACTG1 | P63261 | Actin, cytoplasmic 2 | chr17 | Not Cancer Driver | No | 1 | intact | 73 | 42 | 10 | 10 | 16 |
ACTN1_ENST00000193403 | ACTN1 | P12814 | Alpha-actinin-1 | chr14 | Not Cancer Driver | No | 1 | intact | 108 | 195 | 30 | 30 | 6 |
ACTN4 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | Not Cancer Driver | No | 1 | intact | 131 | 244 | 42 | 42 | 8 |
ACTR2_ENST00000260641 | ACTR2 | P61160 | Actin-related protein 2 | chr2 | Not Cancer Driver | No | 1 | intact | 51 | 6 | 2 | 2 | 0 |
ACTR3 | ACTR3 | P61158 | Actin-related protein 3 | chr2 | Not Cancer Driver | No | 1 | intact | 32 | 16 | 2 | 2 | 0 |
ADAR | ADAR | P55265 | Double-stranded RNA-specific adenosine deaminase | chr1 | Not Cancer Driver | No | 1 | intact | 149 | 675 | 83 | 83 | 12 |
ADD1_ENST00000398129 | ADD1 | P35611 | Alpha-adducin | chr4 | Not Cancer Driver | No | 1 | intact | 106 | 439 | 64 | 64 | 0 |
AFDN_ENST00000447894 | AFDN | P55196 | Afadin | chr6 | Census | Yes | 1 | intact | 248 | 1247 | 180 | 180 | 0 |
ANXA1_ENST00000257497 | ANXA1 | P04083 | Annexin A1 | chr9 | Not Cancer Driver | No | 1 | intact | 59 | 61 | 12 | 12 | 0 |
AP2A1 | AP2A1 | O95782 | AP-2 complex subunit alpha-1 | chr19 | Not Cancer Driver | No | 1 | intact | 95 | 188 | 12 | 12 | 0 |
AP2A2_ENST00000448903 | AP2A2 | O94973 | AP-2 complex subunit alpha-2 | chr11 | Not Cancer Driver | No | 1 | intact | 100 | 145 | 12 | 12 | 0 |
AP2B1_ENST00000621914 | AP2B1 | P63010 | AP-2 complex subunit beta | chr17 | Not Cancer Driver | No | 1 | intact | 85 | 95 | 12 | 12 | 0 |
ARPC3 | ARPC3 | O15145 | Actin-related protein 2/3 complex subunit 3 | chr12 | Not Cancer Driver | No | 1 | intact | 17 | 26 | 6 | 6 | 0 |
ATP1A1_ENST00000295598 | ATP1A1 | P05023 | Sodium/potassium-transporting ATPase subunit alpha-1 | chr1 | Census | Yes | 1 | intact | 115 | 115 | 16 | 16 | 6 |
ATP5F1A_ENST00000282050 | ATP5F1A | P25705 | ATP synthase subunit alpha, mitochondrial | chr18 | Not Cancer Driver | No | 1 | intact | 66 | 23 | 5 | 5 | 2 |
ATP5F1B | ATP5F1B | P06576 | ATP synthase subunit beta, mitochondrial | chr12 | Not Cancer Driver | No | 1 | intact | 60 | 85 | 8 | 8 | 0 |
ATXN1L | ATXN1L | P0C7T5 | Ataxin-1-like | chr16 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 30 | 476 | 19 | 19 | 0 |
BASP1_ENST00000616743 | BASP1 | P80723 | Brain acid soluble protein 1 | chr5 | Not Cancer Driver | No | 1 | intact | 39 | 227 | 39 | 39 | 0 |
BCLAF1 | BCLAF1 | Q9NYF8 | Bcl-2-associated transcription factor 1 | chr6 | Census, Compendium | Yes | 1 | intact | 421 | 899 | 408 | 408 | 0 |
CALD1 | CALD1 | Q05682 | Caldesmon | chr7 | Not Cancer Driver | No | 1 | intact | 133 | 793 | 133 | 133 | 0 |
CALM2 | CALM2 | P0DP24 | Calmodulin-2 | chr2 | Not Cancer Driver | No | 1 | intact | 18 | 115 | 13 | 13 | 8 |
CAPZA1 | CAPZA1 | P52907 | F-actin-capping protein subunit alpha-1 | chr1 | Not Cancer Driver | No | 1 | intact | 40 | 41 | 2 | 2 | 0 |
CAPZB_ENST00000375142 | CAPZB | P47756 | F-actin-capping protein subunit beta | chr1 | Not Cancer Driver | No | 1 | intact | 33 | 66 | 3 | 3 | 0 |
CCT2 | CCT2 | P78371 | T-complex protein 1 subunit beta | chr12 | Not Cancer Driver | No | 1 | intact | 63 | 46 | 3 | 3 | 0 |
CCT3 | CCT3 | P49368 | T-complex protein 1 subunit gamma | chr1 | Not Cancer Driver | No | 1 | intact | 71 | 95 | 12 | 12 | 0 |
CCT5 | CCT5 | P48643 | T-complex protein 1 subunit epsilon | chr5 | Not Cancer Driver | No | 1 | intact | 83 | 72 | 10 | 10 | 1 |
CCT7 | CCT7 | Q99832 | T-complex protein 1 subunit eta | chr2 | Not Cancer Driver | No | 1 | intact | 59 | 36 | 6 | 6 | 0 |
CCT8 | CCT8 | P50990 | T-complex protein 1 subunit theta | chr21 | Not Cancer Driver | No | 1 | intact | 41 | 36 | 2 | 2 | 0 |
CD109 | CD109 | Q6YHK3 | CD109 antigen | chr6 | Not Cancer Driver | No | 1 | intact | 204 | 54 | 11 | 11 | 0 |
CD44 | CD44 | P16070 | CD44 antigen | chr11 | Not Cancer Driver | No | 1 | intact | 75 | 542 | 60 | 60 | 0 |
CD58 | CD58 | P19256 | Lymphocyte function-associated antigen 3 | chr1 | Compendium | Yes | 1 | intact | 29 | 12 | 2 | 2 | 0 |
CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | intact | 39 | 23 | 2 | 2 | 1 |
CDH13_ENST00000567109 | CDH13 | P55290 | Cadherin-13 | chr16 | Not Cancer Driver | No | 1 | intact | 168 | 235 | 59 | 59 | 0 |
CDH2 | CDH2 | P19022 | Cadherin-2 | chr18 | Not Cancer Driver | No | 1 | intact | 238 | 461 | 130 | 130 | 7 |
CFL1_ENST00000308162 | CFL1 | P23528 | Cofilin-1 | chr11 | Not Cancer Driver | No | 1 | intact | 21 | 4 | 0 | 0 | 0 |
CFL2_ENST00000341223 | CFL2 | Q9Y281 | Cofilin-2 | chr14 | Not Cancer Driver | No | 1 | intact | 25 | 0 | 0 | 0 | 1 |
CIC | CIC | Q96RK0 | Protein capicua homolog | chr19 | Census, Compendium | Yes | 2 | intact, hippie, biogrid | 276 | 1550 | 266 | 266 | 0 |
CKAP4 | CKAP4 | Q07065 | Cytoskeleton-associated protein 4 | chr12 | Not Cancer Driver | No | 1 | intact | 73 | 409 | 55 | 55 | 0 |
CLINT1_ENST00000411809 | CLINT1 | Q14677 | Clathrin interactor 1 | chr5 | Not Cancer Driver | No | 1 | intact | 61 | 475 | 51 | 51 | 0 |
CORO1C_ENST00000541050 | CORO1C | Q9ULV4 | Coronin-1C | chr12 | Not Cancer Driver | No | 1 | intact | 61 | 84 | 13 | 13 | 0 |
CRYBG1 | CRYBG1 | Q9Y4K1 | Beta/gamma crystallin domain-containing protein 1 | chr6 | Not Cancer Driver | No | 1 | intact | 211 | 1006 | 124 | 124 | 0 |
CTBP1 | CTBP1 | Q13363 | C-terminal-binding protein 1 | chr4 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 42 | 123 | 9 | 9 | 1 |
CTBP2_ENST00000494626 | CTBP2 | P56545 | C-terminal-binding protein 2 | chr10 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 48 | 94 | 4 | 4 | 0 |
CTNNA2 | CTNNA2 | P26232 | Catenin alpha-2 | chr2 | Census | Yes | 1 | intact | 387 | 307 | 130 | 130 | 0 |
CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | Census, Compendium | Yes | 1 | intact | 415 | 288 | 301 | 301 | 14 |
CTTN_ENST00000301843 | CTTN | Q14247 | Src substrate cortactin | chr11 | Not Cancer Driver | No | 1 | intact | 78 | 465 | 56 | 56 | 0 |
CUL4A | CUL4A | Q13619 | Cullin-4A | chr13 | Not Cancer Driver | No | 1 | intact, hippie | 64 | 102 | 2 | 2 | 0 |
CYP4F12_ENST00000324632 | CYP4F12 | Q9HCS2 | Cytochrome P450 4F12 | chr19 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 138 | 18 | 4 | 4 | 0 |
DAPK3_ENST00000301264 | DAPK3 | O43293 | Death-associated protein kinase 3 | chr19 | Not Cancer Driver | No | 1 | intact | 56 | 82 | 7 | 7 | 0 |
DBN1_ENST00000309007 | DBN1 | Q16643 | Drebrin | chr5 | Not Cancer Driver | No | 1 | intact | 84 | 510 | 73 | 73 | 0 |
DDX1 | DDX1 | Q92499 | ATP-dependent RNA helicase DDX1 | chr2 | Not Cancer Driver | No | 1 | intact | 82 | 91 | 15 | 15 | 0 |
DDX6 | DDX6 | P26196 | Probable ATP-dependent RNA helicase DDX6 | chr11 | Census, Compendium | Yes | 1 | intact | 44 | 129 | 7 | 7 | 5 |
DHX15 | DHX15 | O43143 | ATP-dependent RNA helicase DHX15 | chr4 | Not Cancer Driver | No | 1 | intact | 110 | 180 | 30 | 30 | 0 |
DHX30 | DHX30 | Q7L2E3 | ATP-dependent RNA helicase DHX30 | chr3 | Not Cancer Driver | No | 1 | intact | 165 | 260 | 40 | 40 | 6 |
DHX9 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | Compendium | Yes | 1 | intact | 182 | 331 | 42 | 42 | 0 |
DLST | DLST | P36957 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | chr14 | Not Cancer Driver | No | 1 | intact | 53 | 190 | 32 | 32 | 1 |
DNAJB4 | DNAJB4 | Q9UDY4 | DnaJ homolog subfamily B member 4 | chr1 | Not Cancer Driver | No | 1 | intact | 41 | 160 | 20 | 20 | 0 |
DNASE1L1 | DNASE1L1 | P49184 | Deoxyribonuclease-1-like 1 | chrX | Not Cancer Driver | No | 1 | intact | 30 | 0 | 0 | 0 | 0 |
DNMT3A | DNMT3A | Q9Y6K1 | DNA (cytosine-5)-methyltransferase 3A | chr2 | Census, Compendium | Yes | 1 | hippie | 194 | 371 | 59 | 59 | 16 |
DNMT3B | DNMT3B | Q9UBC3 | DNA (cytosine-5)-methyltransferase 3B | chr20 | Not Cancer Driver | No | 1 | hippie | 153 | 328 | 71 | 71 | 16 |
DSP | DSP | P15924 | Desmoplakin | chr6 | Not Cancer Driver | No | 1 | intact | 483 | 1124 | 204 | 204 | 6 |
DST_ENST00000370788 | DST | Q03001-14 | Isoform 9 of Dystonin | chr6 | Not Cancer Driver | No | 1 | intact | 729 | 1895 | 241 | 241 | 0 |
EDIL3 | EDIL3 | O43854 | EGF-like repeat and discoidin I-like domain-containing protein 3 | chr5 | Not Cancer Driver | No | 1 | intact | 135 | 44 | 16 | 16 | 0 |
EEPD1 | EEPD1 | Q7L9B9 | Endonuclease/exonuclease/phosphatase family domain-containing protein 1 | chr7 | Not Cancer Driver | No | 1 | intact | 86 | 249 | 32 | 32 | 0 |
EIF3A | EIF3A | Q14152 | Eukaryotic translation initiation factor 3 subunit A | chr10 | Not Cancer Driver | No | 1 | intact | 181 | 835 | 130 | 130 | 0 |
EIF3D | EIF3D | O15371 | Eukaryotic translation initiation factor 3 subunit D | chr22 | Not Cancer Driver | No | 1 | intact | 63 | 200 | 26 | 26 | 0 |
EIF3L | EIF3L | Q9Y262 | Eukaryotic translation initiation factor 3 subunit L | chr22 | Not Cancer Driver | No | 1 | intact | 60 | 41 | 1 | 1 | 0 |
ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 2 | intact, hippie | 69 | 43 | 5 | 5 | 0 |
ENO1 | ENO1 | P06733 | Alpha-enolase | chr1 | Not Cancer Driver | No | 1 | intact | 51 | 21 | 2 | 2 | 0 |
ERBIN_ENST00000284037 | ERBIN | Q96RT1 | Erbin | chr5 | Not Cancer Driver | No | 1 | intact | 167 | 967 | 118 | 118 | 0 |
EWSR1_ENST00000397938 | EWSR1 | Q01844 | RNA-binding protein EWS | chr22 | Census, Compendium | Yes | 1 | intact | 94 | 646 | 93 | 93 | 0 |
FAM120C | FAM120C | Q9NX05 | Constitutive coactivator of PPAR-gamma-like protein 2 | chrX | Not Cancer Driver | No | 1 | intact | 162 | 508 | 77 | 77 | 0 |
FAM98A | FAM98A | Q8NCA5 | Protein FAM98A | chr2 | Not Cancer Driver | No | 1 | intact | 63 | 314 | 36 | 36 | 0 |
FBXL17 | FBXL17 | Q9UF56 | F-box/LRR-repeat protein 17 | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 58 | 194 | 1 | 1 | 0 |
FLII | FLII | Q13045 | Protein flightless-1 homolog | chr17 | Not Cancer Driver | No | 1 | intact | 128 | 206 | 32 | 32 | 0 |
FLNB_ENST00000295956 | FLNB | O75369 | Filamin-B | chr3 | Not Cancer Driver | No | 1 | intact | 362 | 1183 | 170 | 170 | 19 |
FLOT1 | FLOT1 | O75955 | Flotillin-1 | chr6 | Not Cancer Driver | No | 1 | intact | 43 | 122 | 15 | 15 | 0 |
FLOT2 | FLOT2 | Q14254 | Flotillin-2 | chr17 | Not Cancer Driver | No | 1 | intact | 56 | 20 | 3 | 3 | 0 |
FMR1 | FMR1 | Q06787 | Synaptic functional regulator FMR1 | chrX | Not Cancer Driver | No | 1 | intact | 124 | 327 | 70 | 70 | 3 |
FUS | FUS | P35637 | RNA-binding protein FUS | chr16 | Census | Yes | 1 | intact | 51 | 524 | 51 | 51 | 20 |
FXR1 | FXR1 | P51114 | Fragile X mental retardation syndrome-related protein 1 | chr3 | Not Cancer Driver | No | 1 | intact | 88 | 312 | 53 | 53 | 0 |
FXR2 | FXR2 | P51116 | Fragile X mental retardation syndrome-related protein 2 | chr17 | Not Cancer Driver | No | 1 | intact | 68 | 388 | 42 | 42 | 0 |
G3BP1 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | Not Cancer Driver | No | 1 | intact | 85 | 352 | 65 | 65 | 0 |
G3BP2_ENST00000395719 | G3BP2 | Q9UN86 | Ras GTPase-activating protein-binding protein 2 | chr4 | Not Cancer Driver | No | 1 | intact | 64 | 384 | 53 | 53 | 0 |
GAPDH | GAPDH | P04406 | Glyceraldehyde-3-phosphate dehydrogenase | chr12 | Not Cancer Driver | No | 1 | intact | 39 | 24 | 3 | 3 | 0 |
GFAP_ENST00000588735 | GFAP | P14136 | Glial fibrillary acidic protein | chr17 | Not Cancer Driver | No | 1 | intact | 65 | 288 | 42 | 42 | 62 |
GLIPR2 | GLIPR2 | Q9H4G4 | Golgi-associated plant pathogenesis-related protein 1 | chr9 | Not Cancer Driver | No | 1 | intact | 16 | 77 | 10 | 10 | 0 |
GNA11 | GNA11 | P29992 | Guanine nucleotide-binding protein subunit alpha-11 | chr19 | Census, Compendium | Yes | 1 | intact | 48 | 10 | 0 | 0 | 5 |
GNAI1 | GNAI1 | P63096 | Guanine nucleotide-binding protein G(i) subunit alpha-1 | chr7 | Not Cancer Driver | No | 1 | intact | 52 | 11 | 3 | 3 | 0 |
GNAI2 | GNAI2 | P04899 | Guanine nucleotide-binding protein G(i) subunit alpha-2 | chr3 | Compendium | Yes | 1 | intact | 50 | 24 | 0 | 0 | 0 |
GNAI3 | GNAI3 | P08754 | Guanine nucleotide-binding protein G(i) subunit alpha-3 | chr1 | Not Cancer Driver | No | 1 | intact | 42 | 11 | 0 | 0 | 1 |
GNAO1_ENST00000638705 | GNAO1 | P09471 | Guanine nucleotide-binding protein G(o) subunit alpha | chr16 | Not Cancer Driver | No | 1 | intact | 54 | 10 | 0 | 0 | 15 |
GNB1_ENST00000378609 | GNB1 | P62873 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | chr1 | Not Cancer Driver | No | 1 | intact | 45 | 24 | 2 | 2 | 16 |
GNG12 | GNG12 | Q9UBI6 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | chr1 | Not Cancer Driver | No | 1 | intact | 10 | 26 | 5 | 5 | 0 |
GPC1 | GPC1 | P35052 | Glypican-1 | chr2 | Not Cancer Driver | No | 1 | intact | 58 | 166 | 14 | 14 | 0 |
GRN | GRN | P28799 | Progranulin | chr17 | Not Cancer Driver | No | 1 | intact | 76 | 29 | 6 | 6 | 1 |
GSN | GSN | P06396 | Gelsolin | chr9 | Not Cancer Driver | No | 1 | intact | 76 | 316 | 28 | 28 | 2 |
GSTP1_ENST00000642444 | GSTP1 | P09211 | Glutathione S-transferase P | chr11 | Not Cancer Driver | No | 1 | intact | 32 | 0 | 0 | 0 | 0 |
HADHA | HADHA | P40939 | Trifunctional enzyme subunit alpha, mitochondrial | chr2 | Not Cancer Driver | No | 1 | intact | 72 | 19 | 2 | 2 | 5 |
HADHB | HADHB | P55084 | Trifunctional enzyme subunit beta, mitochondrial | chr2 | Not Cancer Driver | No | 1 | intact | 71 | 41 | 9 | 9 | 14 |
HNRNPA3 | HNRNPA3 | P51991 | Heterogeneous nuclear ribonucleoprotein A3 | chr2 | Not Cancer Driver | No | 1 | intact | 46 | 285 | 37 | 37 | 0 |
HNRNPAB | HNRNPAB | Q99729 | Heterogeneous nuclear ribonucleoprotein A/B | chr5 | Not Cancer Driver | No | 1 | intact | 31 | 202 | 11 | 11 | 0 |
HNRNPK_ENST00000351839 | HNRNPK | P61978 | Heterogeneous nuclear ribonucleoprotein K | chr9 | Not Cancer Driver | No | 1 | intact | 75 | 302 | 59 | 59 | 0 |
HNRNPM | HNRNPM | P52272 | Heterogeneous nuclear ribonucleoprotein M | chr19 | Not Cancer Driver | No | 1 | intact | 108 | 463 | 67 | 67 | 0 |
HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | Not Cancer Driver | No | 1 | intact | 77 | 504 | 45 | 45 | 0 |
HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | Census, Compendium | Yes | 1 | intact | 106 | 257 | 37 | 37 | 0 |
HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | Census, Compendium | Yes | 1 | intact | 100 | 254 | 43 | 43 | 0 |
HSP90B1 | HSP90B1 | P14625 | Endoplasmin | chr12 | Not Cancer Driver | No | 1 | intact | 94 | 268 | 35 | 35 | 0 |
HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | Not Cancer Driver | No | 1 | intact | 24 | 200 | 13 | 13 | 0 |
HSPA4 | HSPA4 | P34932 | Heat shock 70 kDa protein 4 | chr5 | Not Cancer Driver | No | 1 | intact | 80 | 351 | 24 | 24 | 0 |
HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | Not Cancer Driver | No | 1 | intact | 73 | 282 | 35 | 35 | 0 |
HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 149 | 251 | 52 | 52 | 0 |
HSPA9 | HSPA9 | P38646 | Stress-70 protein, mitochondrial | chr5 | Not Cancer Driver | No | 1 | intact | 67 | 283 | 26 | 26 | 2 |
HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | Not Cancer Driver | No | 1 | intact | 10 | 118 | 8 | 8 | 20 |
HSPH1_ENST00000320027 | HSPH1 | Q92598 | Heat shock protein 105 kDa | chr13 | Not Cancer Driver | No | 1 | intact | 103 | 323 | 42 | 42 | 0 |
IDE | IDE | P14735 | Insulin-degrading enzyme | chr10 | Not Cancer Driver | No | 1 | intact | 90 | 96 | 8 | 8 | 0 |
IFI16_ENST00000295809 | IFI16 | Q16666 | Gamma-interferon-inducible protein 16 | chr1 | Not Cancer Driver | No | 1 | intact | 155 | 419 | 90 | 90 | 0 |
IGF2BP3 | IGF2BP3 | O00425 | Insulin-like growth factor 2 mRNA-binding protein 3 | chr7 | Not Cancer Driver | No | 1 | intact | 79 | 264 | 40 | 40 | 0 |
IMMT | IMMT | Q16891 | MICOS complex subunit MIC60 | chr2 | Not Cancer Driver | No | 1 | intact | 97 | 400 | 50 | 50 | 0 |
INF2 | INF2 | Q27J81 | Inverted formin-2 | chr14 | Not Cancer Driver | No | 1 | intact | 120 | 635 | 49 | 49 | 30 |
IQGAP1 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | Not Cancer Driver | No | 1 | intact | 183 | 351 | 35 | 35 | 0 |
JUP | JUP | P14923 | Junction plakoglobin | chr17 | Not Cancer Driver | No | 1 | intact | 112 | 241 | 37 | 37 | 0 |
KATNAL2_ENST00000356157 | KATNAL2 | Q8IYT4 | Katanin p60 ATPase-containing subunit A-like 2 | chr18 | Not Cancer Driver | No | 1 | intact | 84 | 142 | 30 | 30 | 0 |
KRT18_ENST00000388837 | KRT18 | P05783 | Keratin, type I cytoskeletal 18 | chr12 | Not Cancer Driver | No | 1 | intact | 57 | 179 | 21 | 21 | 4 |
LMO7_ENST00000357063 | LMO7 | Q8WWI1 | LIM domain only protein 7 | chr13 | Not Cancer Driver | No | 1 | intact | 267 | 1102 | 188 | 188 | 0 |
LRRFIP2 | LRRFIP2 | Q9Y608 | Leucine-rich repeat flightless-interacting protein 2 | chr3 | Not Cancer Driver | No | 1 | intact | 75 | 584 | 62 | 62 | 0 |
LUZP1_ENST00000418342 | LUZP1 | Q86V48 | Leucine zipper protein 1 | chr1 | Not Cancer Driver | No | 1 | intact | 102 | 972 | 91 | 91 | 0 |
MAP1B | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | Not Cancer Driver | No | 1 | intact | 332 | 1947 | 278 | 278 | 0 |
MOXD1 | MOXD1 | Q6UVY6 | DBH-like monooxygenase protein 1 | chr6 | Not Cancer Driver | No | 1 | intact | 99 | 29 | 7 | 7 | 0 |
MPRIP_ENST00000341712 | MPRIP | Q6WCQ1 | Myosin phosphatase Rho-interacting protein | chr17 | Not Cancer Driver | No | 1 | intact | 118 | 735 | 95 | 95 | 0 |
MTDH | MTDH | Q86UE4 | Protein LYRIC | chr8 | Not Cancer Driver | No | 1 | intact | 83 | 516 | 81 | 81 | 0 |
MVP | MVP | Q14764 | Major vault protein | chr16 | Not Cancer Driver | No | 1 | intact | 141 | 285 | 31 | 31 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
MYH10_ENST00000269243 | MYH10 | P35580 | Myosin-10 | chr17 | Not Cancer Driver | No | 1 | intact | 258 | 1134 | 136 | 136 | 0 |
MYH14_ENST00000596571 | MYH14 | Q7Z406 | Myosin-14 | chr19 | Not Cancer Driver | No | 1 | intact | 275 | 1215 | 169 | 169 | 5 |
MYH9 | MYH9 | P35579 | Myosin-9 | chr22 | Census, Compendium | Yes | 1 | intact | 310 | 1120 | 160 | 160 | 17 |
MYL6_ENST00000548293 | MYL6 | P60660 | Myosin light polypeptide 6 | chr12 | Not Cancer Driver | No | 1 | intact | 13 | 17 | 1 | 1 | 0 |
MYLIP | MYLIP | Q8WY64 | E3 ubiquitin-protein ligase MYLIP | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 56 | 11 | 2 | 2 | 0 |
MYLK | MYLK | Q15746 | Myosin light chain kinase, smooth muscle | chr3 | Not Cancer Driver | No | 1 | intact | 343 | 957 | 184 | 184 | 3 |
MYO1B | MYO1B | O43795 | Unconventional myosin-Ib | chr2 | Not Cancer Driver | No | 1 | intact | 144 | 34 | 4 | 4 | 0 |
MYO1C | MYO1C | O00159 | Unconventional myosin-Ic | chr17 | Not Cancer Driver | No | 1 | intact | 110 | 66 | 11 | 11 | 0 |
MYO6 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | Not Cancer Driver | No | 1 | intact | 176 | 342 | 41 | 41 | 3 |
MYOF | MYOF | Q9NZM1 | Myoferlin | chr10 | Not Cancer Driver | No | 1 | intact | 269 | 401 | 55 | 55 | 0 |
NCL | NCL | P19338 | Nucleolin | chr2 | Not Cancer Driver | No | 1 | intact | 85 | 569 | 68 | 68 | 0 |
NES | NES | P48681 | Nestin | chr1 | Not Cancer Driver | No | 1 | intact | 271 | 1474 | 253 | 253 | 0 |
NEXN | NEXN | Q0ZGT2 | Nexilin | chr1 | Not Cancer Driver | No | 1 | intact | 111 | 614 | 102 | 102 | 4 |
NPM1 | NPM1 | P06748 | Nucleophosmin | chr5 | Census, Compendium | Yes | 1 | intact | 29 | 249 | 22 | 22 | 0 |
NT5E | NT5E | P21589 | 5'-nucleotidase | chr6 | Not Cancer Driver | No | 1 | intact | 61 | 26 | 2 | 2 | 1 |
NUFIP2 | NUFIP2 | Q7Z417 | Nuclear fragile X mental retardation-interacting protein 2 | chr17 | Not Cancer Driver | No | 1 | intact | 67 | 623 | 62 | 62 | 0 |
OGDH | OGDH | Q02218 | 2-oxoglutarate dehydrogenase complex component E1 | chr7 | Not Cancer Driver | No | 1 | intact | 150 | 106 | 19 | 19 | 0 |
PABPC1 | PABPC1 | P11940 | Polyadenylate-binding protein 1 | chr8 | Census, Compendium | Yes | 1 | intact | 100 | 317 | 55 | 55 | 0 |
PABPC4_ENST00000372857 | PABPC4 | Q13310 | Polyadenylate-binding protein 4 | chr1 | Not Cancer Driver | No | 1 | intact | 89 | 253 | 49 | 49 | 0 |
PAK1_ENST00000356341 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 57 | 299 | 30 | 30 | 2 |
PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | Not Cancer Driver | No | 1 | intact | 119 | 320 | 34 | 34 | 0 |
PDE8A_ENST00000394553 | PDE8A | O60658 | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | chr15 | Not Cancer Driver | No | 1 | intact | 78 | 187 | 17 | 17 | 0 |
PHLDB2 | PHLDB2 | Q86SQ0 | Pleckstrin homology-like domain family B member 2 | chr3 | Not Cancer Driver | No | 1 | intact | 235 | 1030 | 190 | 190 | 0 |
PIK3R3_ENST00000372006 | PIK3R3 | Q92569 | Phosphatidylinositol 3-kinase regulatory subunit gamma | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 149 | 20 | 20 | 0 |
PKM_ENST00000335181 | PKM | P14618 | Pyruvate kinase PKM | chr15 | Not Cancer Driver | No | 1 | intact | 78 | 58 | 13 | 13 | 0 |
PLCD1_ENST00000334661 | PLCD1 | P51178 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 | chr3 | Not Cancer Driver | No | 1 | intact | 94 | 111 | 13 | 13 | 2 |
PLEC | PLEC | Q15149 | Plectin | chr8 | Not Cancer Driver | No | 1 | intact | 677 | 2130 | 272 | 272 | 2 |
POMGNT1_ENST00000371984 | POMGNT1 | Q8WZA1 | Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 75 | 90 | 13 | 13 | 20 |
PPP1CA_ENST00000376745 | PPP1CA | P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | chr11 | Not Cancer Driver | No | 1 | intact | 38 | 27 | 6 | 6 | 0 |
PPP1CB_ENST00000358506 | PPP1CB | P62140 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | chr2 | Not Cancer Driver | No | 1 | intact | 47 | 25 | 5 | 5 | 5 |
PPP1R12A_ENST00000261207 | PPP1R12A | O14974 | Protein phosphatase 1 regulatory subunit 12A | chr12 | Not Cancer Driver | No | 1 | intact | 107 | 821 | 89 | 89 | 0 |
PPP1R12B_ENST00000608999 | PPP1R12B | O60237 | Protein phosphatase 1 regulatory subunit 12B | chr1 | Not Cancer Driver | No | 1 | intact | 143 | 801 | 119 | 119 | 0 |
PPP1R12C | PPP1R12C | Q9BZL4 | Protein phosphatase 1 regulatory subunit 12C | chr19 | Not Cancer Driver | No | 1 | intact | 70 | 605 | 55 | 55 | 0 |
PPP1R18_ENST00000615527 | PPP1R18 | Q6NYC8 | Phostensin | chr6 | Not Cancer Driver | No | 1 | intact | 51 | 585 | 49 | 49 | 0 |
PRMT5 | PRMT5 | O14744 | Protein arginine N-methyltransferase 5 | chr14 | Not Cancer Driver | No | 1 | intact | 83 | 72 | 6 | 6 | 0 |
RAP2B | RAP2B | P61225 | Ras-related protein Rap-2b | chr3 | Not Cancer Driver | No | 1 | intact | 22 | 0 | 0 | 0 | 0 |
RASA3 | RASA3 | Q14644 | Ras GTPase-activating protein 3 | chr13 | Not Cancer Driver | No | 1 | intact | 118 | 101 | 19 | 19 | 0 |
RBM12B | RBM12B | Q8IXT5 | RNA-binding protein 12B | chr8 | Not Cancer Driver | No | 1 | intact | 133 | 524 | 79 | 79 | 0 |
RCBTB1 | RCBTB1 | Q8NDN9 | RCC1 and BTB domain-containing protein 1 | chr13 | Not Cancer Driver | No | 1 | intact | 54 | 11 | 4 | 4 | 4 |
RCBTB2_ENST00000344532 | RCBTB2 | O95199 | RCC1 and BTB domain-containing protein 2 | chr13 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 86 | 36 | 3 | 3 | 0 |
RP2 | RP2 | O75695 | Protein XRP2 | chrX | Not Cancer Driver | No | 1 | intact | 45 | 28 | 6 | 6 | 10 |
RPL12 | RPL12 | P30050 | 60S ribosomal protein L12 | chr9 | Not Cancer Driver | No | 1 | intact | 13 | 75 | 6 | 6 | 0 |
RPL38_ENST00000439590 | RPL38 | P63173 | 60S ribosomal protein L38 | chr17 | Not Cancer Driver | No | 1 | intact | 2 | 9 | 0 | 0 | 0 |
RPL5_ENST00000370321 | RPL5 | P46777 | 60S ribosomal protein L5 | chr1 | Census | Yes | 1 | intact | 57 | 96 | 17 | 17 | 2 |
RPLP1 | RPLP1 | P05386 | 60S acidic ribosomal protein P1 | chr15 | Not Cancer Driver | No | 1 | intact | 6 | 45 | 2 | 2 | 0 |
RPN1 | RPN1 | P04843 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | chr3 | Census | Yes | 1 | intact | 50 | 69 | 3 | 3 | 0 |
RPS13 | RPS13 | P62277 | 40S ribosomal protein S13 | chr11 | Not Cancer Driver | No | 1 | intact | 19 | 18 | 5 | 5 | 0 |
RPS3A | RPS3A | P61247 | 40S ribosomal protein S3a | chr4 | Compendium | Yes | 1 | intact | 21 | 85 | 5 | 5 | 0 |
RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | Not Cancer Driver | No | 1 | intact | 22 | 48 | 4 | 4 | 0 |
RPS7_ENST00000645674 | RPS7 | P62081 | 40S ribosomal protein S7 | chr2 | Not Cancer Driver | No | 1 | intact | 29 | 39 | 7 | 7 | 0 |
RPS8 | RPS8 | P62241 | 40S ribosomal protein S8 | chr1 | Not Cancer Driver | No | 1 | intact | 23 | 81 | 7 | 7 | 0 |
RRAS2 | RRAS2 | P62070 | Ras-related protein R-Ras2 | chr11 | Compendium | Yes | 1 | intact | 29 | 37 | 1 | 1 | 4 |
RRBP1_ENST00000246043 | RRBP1 | Q9P2E9 | Ribosome-binding protein 1 | chr20 | Not Cancer Driver | No | 1 | intact | 164 | 1301 | 151 | 151 | 0 |
RTRAF | RTRAF | Q9Y224 | RNA transcription, translation and transport factor protein | chr14 | Not Cancer Driver | No | 1 | intact | 24 | 35 | 1 | 1 | 0 |
SEMA7A | SEMA7A | O75326 | Semaphorin-7A | chr15 | Not Cancer Driver | No | 1 | intact | 81 | 150 | 21 | 21 | 0 |
SNX1_ENST00000559844 | SNX1 | Q13596 | Sorting nexin-1 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 214 | 25 | 25 | 0 |
SORBS2_ENST00000284776 | SORBS2 | O94875 | Sorbin and SH3 domain-containing protein 2 | chr4 | Not Cancer Driver | No | 1 | intact | 172 | 854 | 137 | 137 | 0 |
SPECC1L | SPECC1L | Q69YQ0 | Cytospin-A | chr22 | Not Cancer Driver | No | 1 | intact | 113 | 928 | 93 | 93 | 3 |
SPTAN1_ENST00000372731 | SPTAN1 | Q13813 | Spectrin alpha chain, non-erythrocytic 1 | chr9 | Not Cancer Driver | No | 1 | intact | 315 | 980 | 114 | 114 | 0 |
SPTBN1 | SPTBN1 | Q01082 | Spectrin beta chain, non-erythrocytic 1 | chr2 | Not Cancer Driver | No | 1 | intact | 311 | 869 | 123 | 123 | 0 |
SQSTM1 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | Not Cancer Driver | No | 1 | intact | 54 | 267 | 32 | 32 | 30 |
SRP14 | SRP14 | P37108 | Signal recognition particle 14 kDa protein | chr15 | Not Cancer Driver | No | 1 | intact | 10 | 74 | 8 | 8 | 0 |
STAU1 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | Not Cancer Driver | No | 1 | intact | 77 | 456 | 63 | 63 | 0 |
SVIL | SVIL | O95425 | Supervillin | chr10 | Not Cancer Driver | No | 1 | intact | 308 | 1423 | 192 | 192 | 0 |
SYNPO | SYNPO | Q8N3V7 | Synaptopodin | chr5 | Not Cancer Driver | No | 1 | intact | 103 | 918 | 102 | 102 | 0 |
TFCP2 | TFCP2 | Q12800 | Alpha-globin transcription factor CP2 | chr12 | Not Cancer Driver | No | 1 | intact | 68 | 169 | 23 | 23 | 0 |
THY1 | THY1 | P04216 | Thy-1 membrane glycoprotein | chr11 | Not Cancer Driver | No | 1 | intact | 24 | 5 | 0 | 0 | 0 |
TJP1_ENST00000346128 | TJP1 | Q07157 | Tight junction protein ZO-1 | chr15 | Not Cancer Driver | No | 1 | intact | 198 | 1350 | 151 | 151 | 0 |
TMOD3 | TMOD3 | Q9NYL9 | Tropomodulin-3 | chr15 | Not Cancer Driver | No | 1 | intact | 40 | 190 | 24 | 24 | 0 |
TNIP2 | TNIP2 | Q8NFZ5 | TNFAIP3-interacting protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 43 | 316 | 36 | 36 | 0 |
TNKS1BP1 | TNKS1BP1 | Q9C0C2 | 182 kDa tankyrase-1-binding protein | chr11 | Not Cancer Driver | No | 1 | intact | 221 | 1712 | 219 | 219 | 0 |
TPM1_ENST00000403994 | TPM1 | P09493 | Tropomyosin alpha-1 chain | chr15 | Not Cancer Driver | No | 1 | intact | 33 | 234 | 29 | 29 | 8 |
TPM3 | TPM3 | P06753 | Tropomyosin alpha-3 chain | chr1 | Census | Yes | 1 | intact | 35 | 230 | 27 | 27 | 21 |
TPM4_ENST00000300933 | TPM4 | P67936 | Tropomyosin alpha-4 chain | chr19 | Census | Yes | 1 | intact | 28 | 216 | 28 | 28 | 0 |
TPRN | TPRN | Q4KMQ1 | Taperin | chr9 | Not Cancer Driver | No | 1 | intact | 41 | 667 | 36 | 36 | 0 |
TRPS1_ENST00000220888 | TRPS1 | Q9UHF7 | Zinc finger transcription factor Trps1 | chr8 | Not Cancer Driver | No | 1 | intact | 348 | 800 | 216 | 216 | 7 |
TSN | TSN | Q15631 | Translin | chr2 | Not Cancer Driver | No | 1 | hippie | 30 | 0 | 0 | 0 | 0 |
TWF1_ENST00000395510 | TWF1 | Q12792 | Twinfilin-1 | chr12 | Not Cancer Driver | No | 1 | intact | 50 | 52 | 3 | 3 | 0 |
TXNIP | TXNIP | Q9H3M7 | Thioredoxin-interacting protein | chr1 | Not Cancer Driver | No | 1 | intact | 61 | 77 | 14 | 14 | 0 |
UACA | UACA | Q9BZF9 | Uveal autoantigen with coiled-coil domains and ankyrin repeats | chr15 | Not Cancer Driver | No | 1 | intact | 177 | 863 | 101 | 101 | 0 |
UBP1 | UBP1 | Q9NZI7 | Upstream-binding protein 1 | chr3 | Not Cancer Driver | No | 1 | intact | 58 | 233 | 29 | 29 | 0 |
ULBP2 | ULBP2 | Q9BZM5 | UL16-binding protein 2 | chr6 | Not Cancer Driver | No | 1 | intact | 33 | 25 | 2 | 2 | 0 |
UPF1 | UPF1 | Q92900 | Regulator of nonsense transcripts 1 | chr19 | Not Cancer Driver | No | 1 | intact | 146 | 329 | 36 | 36 | 0 |
USP10_ENST00000219473 | USP10 | Q14694 | Ubiquitin carboxyl-terminal hydrolase 10 | chr16 | Not Cancer Driver | No | 1 | intact | 92 | 425 | 49 | 49 | 0 |
VARS | VARS1 | P26640 | Valine--tRNA ligase | chr6 | Not Cancer Driver | No | 1 | intact | 145 | 251 | 26 | 26 | 0 |
VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 1 | intact | 88 | 186 | 16 | 16 | 16 |
VDAC1_ENST00000395047 | VDAC1 | P21796 | Voltage-dependent anion-selective channel protein 1 | chr5 | Not Cancer Driver | No | 1 | intact | 38 | 36 | 4 | 4 | 0 |
VIM_ENST00000224237 | VIM | P08670 | Vimentin | chr10 | Not Cancer Driver | No | 1 | intact | 84 | 316 | 57 | 57 | 1 |
WDR1 | WDR1 | O75083 | WD repeat-containing protein 1 | chr4 | Not Cancer Driver | No | 1 | intact | 66 | 30 | 7 | 7 | 2 |
XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | Not Cancer Driver | No | 1 | intact | 87 | 118 | 11 | 11 | 0 |
XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | Not Cancer Driver | No | 1 | intact | 66 | 140 | 12 | 12 | 0 |
YBX1 | YBX1 | P67809 | Y-box-binding protein 1 | chr1 | Not Cancer Driver | No | 1 | intact | 41 | 312 | 41 | 41 | 0 |
YBX3 | YBX3 | P16989 | Y-box-binding protein 3 | chr12 | Not Cancer Driver | No | 1 | intact | 49 | 359 | 47 | 47 | 0 |
ZBTB18_ENST00000622512 | ZBTB18 | Q99592 | Zinc finger and BTB domain-containing protein 18 | chr1 | Not Cancer Driver | No | 1 | intact | 78 | 236 | 25 | 25 | 0 |
ZBTB2 | ZBTB2 | Q8N680 | Zinc finger and BTB domain-containing protein 2 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 75 | 216 | 30 | 30 | 0 |
ZBTB3 | ZBTB3 | Q9H5J0 | Zinc finger and BTB domain-containing protein 3 | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 68 | 352 | 35 | 35 | 0 |
ZBTB42 | ZBTB42 | B2RXF5 | Zinc finger and BTB domain-containing protein 42 | chr14 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 15 | 174 | 6 | 6 | 1 |
ZC3HAV1 | ZC3HAV1 | Q7Z2W4 | Zinc finger CCCH-type antiviral protein 1 | chr7 | Not Cancer Driver | No | 1 | intact | 142 | 344 | 63 | 63 | 0 |
ZDHHC5 | ZDHHC5 | Q9C0B5 | Palmitoyltransferase ZDHHC5 | chr11 | Not Cancer Driver | No | 1 | intact | 89 | 462 | 63 | 63 | 0 |
ZNF131 | ZNF131 | P52739 | Zinc finger protein 131 | chr5 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 79 | 266 | 41 | 41 | 0 |
ZNF516 | ZNF516 | Q92618 | Zinc finger protein 516 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 177 | 861 | 131 | 131 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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