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WLS_ENST00000262348 ,WLS ,Q5T9L3
  • Uniprot Accession= Q5T9L3
  • Ensembl Transcript= ENST00000262348.8
  • Uniprot Name= WLS
  • Name= Protein wntless homolog
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 43
  • Number of Interaction partner in biogrid: 47
  • Number of Interaction partner in hippie: 115
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 Not Cancer Driver No 2 intact, hippie 61 93 11 11 0
AGMO AGMO Q6ZNB7 Alkylglycerol monooxygenase chr7 Not Cancer Driver No 1 hippie 134 7 2 2 0
AQP4 AQP4 P55087 Aquaporin-4 chr18 Not Cancer Driver No 2 intact, hippie 50 30 9 9 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 157 80 11 11 1
BORCS7_ENST00000369883 BORCS7 Q96B45 BLOC-1-related complex subunit 7 chr10 Not Cancer Driver No 1 intact, hippie 10 45 3 3 0
C7orf25_ENST00000438029 C7orf25 Q9BPX7 UPF0415 protein C7orf25 chr7 Not Cancer Driver No 1 intact, hippie 46 66 7 7 0
CAP1_ENST00000372805 CAP1 Q01518 Adenylyl cyclase-associated protein 1 chr1 Not Cancer Driver No 1 intact, hippie 70 156 31 31 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 Not Cancer Driver No 1 intact, hippie 81 23 1 1 0
CD63_ENST00000552692 CD63 P08962 CD63 antigen chr12 Not Cancer Driver No 2 hippie, biogrid 27 0 0 0 0
CGRRF1 CGRRF1 Q99675 Cell growth regulator with RING finger domain protein 1 chr14 Not Cancer Driver No 1 hippie 31 34 5 5 0
CHORDC1 CHORDC1 Q9UHD1 Cysteine and histidine-rich domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie 47 119 17 17 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 Not Cancer Driver No 1 intact 27 70 12 12 0
CHRNA4 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 Not Cancer Driver No 1 hippie, biogrid 144 186 33 33 2
CHRNB1 CHRNB1 P11230 Acetylcholine receptor subunit beta chr17 Not Cancer Driver No 1 hippie, biogrid 62 45 9 9 3
CHRND CHRND Q07001 Acetylcholine receptor subunit delta chr2 Not Cancer Driver No 2 hippie, biogrid 110 71 19 19 7
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 Not Cancer Driver No 2 hippie, biogrid 56 5 2 2 0
CNIH4 CNIH4 Q9P003 Protein cornichon homolog 4 chr1 Not Cancer Driver No 2 intact, hippie 13 0 0 0 0
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 Not Cancer Driver No 1 hippie 25 20 0 0 0
DPM2 DPM2 O94777 Dolichol phosphate-mannose biosynthesis regulatory protein chr9 Not Cancer Driver No 1 intact, hippie 9 0 0 0 1
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 Not Cancer Driver No 1 intact, hippie 127 124 45 45 0
DUOXA2 DUOXA2 Q1HG44 Dual oxidase maturation factor 2 chr15 Not Cancer Driver No 1 hippie, biogrid 40 0 0 0 0
EBP EBP Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase chrX Not Cancer Driver No 1 intact, hippie 30 9 0 0 9
EMC7 EMC7 Q9NPA0 ER membrane protein complex subunit 7 chr15 Not Cancer Driver No 2 intact, hippie 35 54 10 10 0
ERLIN2_ENST00000519638 ERLIN2 O94905 Erlin-2 chr8 Not Cancer Driver No 1 hippie 38 22 3 3 0
FAF2 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 hippie 54 171 16 16 0
FAM241B FAM241B Q96D05 Protein FAM241B chr10 Not Cancer Driver No 1 intact, hippie 25 53 9 9 0
FCER1A FCER1A P12319 High affinity immunoglobulin epsilon receptor subunit alpha chr1 Not Cancer Driver No 1 hippie, biogrid 83 13 4 4 0
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 45 2 0 0 0
GABRA3_ENST00000535043 GABRA3 P34903 Gamma-aminobutyric acid receptor subunit alpha-3 chrX Not Cancer Driver No 1 hippie, biogrid 136 47 10 10 0
GJD3 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 5 79 0 0 0
GPM6A_ENST00000393658 GPM6A P51674 Neuronal membrane glycoprotein M6-a chr4 Not Cancer Driver No 1 intact, hippie 83 15 5 5 0
GPR182 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 49 33 4 4 0
GPR37 GPR37 O15354 Prosaposin receptor GPR37 chr7 Not Cancer Driver No 1 intact, hippie 124 200 42 42 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 107 16 4 4 18
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 Not Cancer Driver No 1 intact, hippie 96 122 26 26 0
HTR3A_ENST00000504030 HTR3A P46098 5-hydroxytryptamine receptor 3A chr11 Not Cancer Driver No 2 hippie, biogrid 127 45 13 13 0
HTR3C HTR3C Q8WXA8 5-hydroxytryptamine receptor 3C chr3 Not Cancer Driver No 3 hippie, biogrid 82 35 7 7 0
IRF2 IRF2 P14316 Interferon regulatory factor 2 chr4 Not Cancer Driver No 1 hippie 85 288 73 73 0
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 Not Cancer Driver No 1 hippie 103 49 11 11 12
KMT2C_ENST00000355193 KMT2C Q8NEZ4 Histone-lysine N-methyltransferase 2C chr7 Census, Compendium Yes 1 intact, hippie 835 3599 517 517 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 intact, hippie, biogrid 788 7 2 2 27
LAMP3 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 67 222 38 38 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LNPK_ENST00000272748 LNPK Q9C0E8 Endoplasmic reticulum junction formation protein lunapark chr2 Not Cancer Driver No 1 hippie 62 257 43 43 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
NCSTN NCSTN Q92542 Nicastrin chr1 Not Cancer Driver No 1 intact, hippie 94 72 11 11 1
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 155 24 0 0 150
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 Not Cancer Driver No 1 hippie 91 30 3 3 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 Not Cancer Driver No 1 intact, hippie 117 18 5 5 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 Not Cancer Driver No 4 intact, hippie 107 58 27 27 0
ORAI1 ORAI1 Q96D31 Calcium release-activated calcium channel protein 1 chr12 Not Cancer Driver No 1 intact, hippie 26 101 9 9 5
PCDHB10 PCDHB10 Q9UN67 Protocadherin beta-10 chr5 Not Cancer Driver No 2 intact, hippie 240 124 31 31 0
PEX11B PEX11B O96011 Peroxisomal membrane protein 11B chr1 Not Cancer Driver No 1 hippie 30 22 3 3 0
POMK POMK Q9H5K3 Protein O-mannose kinase chr8 Not Cancer Driver No 1 intact, hippie, biogrid 53 30 9 9 3
PORCN PORCN Q9H237 Protein-serine O-palmitoleoyltransferase porcupine chrX Not Cancer Driver No 1 hippie 77 0 0 0 15
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 22 58 4 4 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RAB4A RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 26 32 11 11 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 32 65 15 15 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 24 50 4 4 0
RAB9A RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 1 hippie, biogrid 18 21 1 1 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 2 hippie, biogrid 52 19 2 2 0
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 30 53 7 7 0
RNF128 RNF128 Q8TEB7 E3 ubiquitin-protein ligase RNF128 chrX Not Cancer Driver No 1 hippie 61 123 15 15 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 Not Cancer Driver No 1 hippie 44 33 2 2 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 50 69 3 3 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 53 26 4 4 0
RPRM RPRM Q9NS64 Protein reprimo chr2 Not Cancer Driver No 1 hippie, biogrid 29 1 0 0 0
SEC61B SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 11 60 7 7 0
SEC62 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 41 211 23 23 0
SGIP1 SGIP1 Q9BQI5 SH3-containing GRB2-like protein 3-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 210 559 152 152 0
SIDT2_ENST00000620360 SIDT2 Q8NBJ9 SID1 transmembrane family member 2 chr11 Not Cancer Driver No 1 hippie, biogrid 113 23 6 6 0
SLC22A9 SLC22A9 Q8IVM8 Solute carrier family 22 member 9 chr11 Not Cancer Driver No 1 hippie, biogrid 152 34 10 10 0
SLC6A3 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 Not Cancer Driver No 1 intact, hippie 150 31 8 8 2
SMO SMO Q99835 Smoothened homolog chr7 Census, Compendium Yes 1 hippie 112 241 27 27 1
SNX8 SNX8 Q9Y5X2 Sorting nexin-8 chr7 Not Cancer Driver No 1 hippie, biogrid 64 114 15 15 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 Compendium Yes 2 intact, hippie 86 495 82 82 18
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 20 20 0
STYK1 STYK1 Q6J9G0 Tyrosine-protein kinase STYK1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 83 35 10 10 0
TCTN2 TCTN2 Q96GX1 Tectonic-2 chr12 Not Cancer Driver No 1 intact, hippie 75 23 2 2 0
TCTN3 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 intact, hippie 45 71 8 8 1
TMED6 TMED6 Q8WW62 Transmembrane emp24 domain-containing protein 6 chr16 Not Cancer Driver No 1 hippie, biogrid 24 42 4 4 0
TMEM134 TMEM134 Q9H6X4 Transmembrane protein 134 chr11 Not Cancer Driver No 1 intact, hippie 8 72 0 0 0
TMEM14A TMEM14A Q9Y6G1 Transmembrane protein 14A chr6 Not Cancer Driver No 1 hippie 10 0 0 0 0
TMEM160 TMEM160 Q9NX00 Transmembrane protein 160 chr19 Not Cancer Driver No 2 intact, hippie 8 46 1 1 0
TMEM230_ENST00000379286 TMEM230 Q96A57 Transmembrane protein 230 chr20 Not Cancer Driver No 1 intact, hippie 23 0 0 0 0
TMPRSS4_ENST00000437212 TMPRSS4 Q9NRS4 Transmembrane protease serine 4 chr11 Not Cancer Driver No 1 hippie, biogrid 47 35 4 4 0
TOMM6_ENST00000398881 TOMM6 Q96B49 Mitochondrial import receptor subunit TOM6 homolog chr6 Not Cancer Driver No 1 intact, hippie 6 18 2 2 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TVP23B TVP23B Q9NYZ1 Golgi apparatus membrane protein TVP23 homolog B chr17 Not Cancer Driver No 2 intact, hippie 16 21 4 4 0
UBXN4 UBXN4 Q92575 UBX domain-containing protein 4 chr2 Not Cancer Driver No 1 hippie 69 302 41 41 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 intact, hippie 38 36 4 4 0
VIPR1 VIPR1 P32241 Vasoactive intestinal polypeptide receptor 1 chr3 Not Cancer Driver No 1 hippie, biogrid 41 10 2 2 0
WLS_ENST00000262348 WLS Q5T9L3 Protein wntless homolog chr1 Not Cancer Driver No 1 intact, hippie 71 14 3 3 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 Not Cancer Driver No 1 hippie 29 25 0 0 8
WNT16 WNT16 Q9UBV4 Protein Wnt-16 chr7 Not Cancer Driver No 1 hippie, biogrid 59 28 9 9 0
WNT2 WNT2 P09544 Protein Wnt-2 chr7 Not Cancer Driver No 1 hippie, biogrid 85 11 3 3 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 Not Cancer Driver No 3 intact, hippie, biogrid 77 37 5 5 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 Not Cancer Driver No 3 hippie, biogrid 30 39 4 4 4
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 Not Cancer Driver No 3 intact, hippie, biogrid 66 0 0 0 2
WNT5B_ENST00000310594 WNT5B Q9H1J7 Protein Wnt-5b chr12 Not Cancer Driver No 1 intact, hippie 60 23 4 4 0
WNT7A WNT7A O00755 Protein Wnt-7a chr3 Not Cancer Driver No 2 intact, hippie, biogrid 93 18 9 9 4
WNT7B WNT7B P56706 Protein Wnt-7b chr22 Not Cancer Driver No 1 intact, hippie 55 11 1 1 0
WNT8A_ENST00000398754 WNT8A Q9H1J5 Protein Wnt-8a chr5 Not Cancer Driver No 1 hippie 50 3 0 0 0
WNT8B WNT8B Q93098 Protein Wnt-8b chr10 Not Cancer Driver No 1 intact, hippie 50 27 5 5 0
WNT9A WNT9A O14904 Protein Wnt-9a chr1 Not Cancer Driver No 1 intact, hippie 74 44 11 11 0
WNT9B WNT9B O14905 Protein Wnt-9b chr17 Not Cancer Driver No 1 hippie 47 11 4 4 0
YIPF6 YIPF6 Q96EC8 Protein YIPF6 chrX Not Cancer Driver No 1 hippie 42 20 5 5 0