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WASF2 ,WASF2 ,Q9Y6W5
  • Uniprot Accession= Q9Y6W5
  • Ensembl Transcript= ENST00000618852.4
  • Uniprot Name= WASF2
  • Name= Wiskott-Aldrich syndrome protein family member 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 32
  • Number of Interaction partner in biogrid: 43
  • Number of Interaction partner in hippie: 98
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 Census, Compendium Yes 5 intact, hippie, biogrid 55 360 39 39 0
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 56 361 38 38 0
ABI3 ABI3 Q9P2A4 ABI gene family member 3 chr17 Not Cancer Driver No 1 hippie 46 248 31 31 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 2 hippie, biogrid 112 43 5 5 5
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 Not Cancer Driver No 1 hippie 51 6 2 2 0
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 Not Cancer Driver No 2 hippie, biogrid 32 16 2 2 0
AMZ1 AMZ1 Q400G9 Archaemetzincin-1 chr7 Not Cancer Driver No 2 hippie, biogrid 78 147 18 18 0
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 Not Cancer Driver No 1 hippie 105 399 58 58 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
ARHGAP12 ARHGAP12 Q8IWW6 Rho GTPase-activating protein 12 chr10 Not Cancer Driver No 1 hippie, biogrid 97 497 56 56 0
ARPC3 ARPC3 O15145 Actin-related protein 2/3 complex subunit 3 chr12 Not Cancer Driver No 1 hippie 17 26 6 6 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 Not Cancer Driver No 4 intact, hippie, biogrid 85 330 52 52 0
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 124 656 86 86 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 115 546 73 73 10
BRK1 BRK1 Q8WUW1 Protein BRICK1 chr3 Not Cancer Driver No 1 hippie, biogrid 7 14 1 1 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX Census, Compendium Yes 1 hippie 147 114 27 27 110
C11orf52 C11orf52 Q96A22 Uncharacterized protein C11orf52 chr11 Not Cancer Driver No 1 hippie, biogrid 15 108 12 12 0
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 Not Cancer Driver No 1 hippie 57 84 10 10 0
CBLC_ENST00000647358 CBLC Q9ULV8 E3 ubiquitin-protein ligase CBL-C chr19 Census Yes 2 intact, hippie, biogrid 60 128 21 21 0
CCDC27 CCDC27 Q2M243 Coiled-coil domain-containing protein 27 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 107 423 67 67 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CEP19 CEP19 Q96LK0 Centrosomal protein of 19 kDa chr3 Not Cancer Driver No 1 intact, hippie 30 71 11 11 0
CNGA4 CNGA4 Q8IV77 Cyclic nucleotide-gated cation channel alpha-4 chr11 Not Cancer Driver No 1 hippie, biogrid 132 79 13 13 0
CTTN_ENST00000301843 CTTN Q14247 Src substrate cortactin chr11 Not Cancer Driver No 1 intact 78 465 56 56 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 46 96 0 0 0
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 211 86 11 11 3
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DOCK1_ENST00000280333 DOCK1 Q14185 Dedicator of cytokinesis protein 1 chr10 Not Cancer Driver No 1 hippie 240 360 52 52 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 Not Cancer Driver No 1 intact 182 140 24 24 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 Census, Compendium Yes 1 intact 280 71 15 15 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 Not Cancer Driver No 1 intact 186 119 17 17 7
EPS8L1 EPS8L1 Q8TE68 Epidermal growth factor receptor kinase substrate 8-like protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 116 521 96 96 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EVL_ENST00000402714 EVL Q9UI08 Ena/VASP-like protein chr14 Not Cancer Driver No 1 intact, hippie, biogrid 42 335 37 37 0
EZR EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie 66 295 35 35 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 intact 152 230 43 43 74
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 intact 113 162 28 28 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GAS7 GAS7 O60861 Growth arrest-specific protein 7 chr17 Census Yes 1 hippie 78 318 57 57 0
GJB7 GJB7 Q6PEY0 Gap junction beta-7 protein chr6 Not Cancer Driver No 2 intact, hippie, biogrid 30 0 0 0 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HOMER3_ENST00000542541 HOMER3 Q9NSC5 Homer protein homolog 3 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 31 251 15 15 0
HOOK3 HOOK3 Q86VS8 Protein Hook homolog 3 chr8 Census Yes 1 hippie 79 493 55 55 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 107 16 4 4 18
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
ITSN2 ITSN2 Q9NZM3 Intersectin-2 chr2 Not Cancer Driver No 1 hippie 207 680 92 92 0
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 Not Cancer Driver No 1 hippie 183 804 100 100 0
KCTD10 KCTD10 Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 chr12 Not Cancer Driver No 1 hippie 68 73 19 19 0
KIAA1522_ENST00000373480 KIAA1522 Q9P206 Uncharacterized protein KIAA1522 chr1 Not Cancer Driver No 1 hippie, biogrid 143 1007 140 140 0
KLF16 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 hippie, biogrid 13 204 8 8 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 hippie, biogrid 788 7 2 2 27
LHX4 LHX4 Q969G2 LIM/homeobox protein Lhx4 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 75 219 45 45 4
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 95 84 12 12 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 hippie, biogrid 48 111 17 17 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 Not Cancer Driver No 3 hippie, biogrid 89 88 19 19 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 Not Cancer Driver No 1 hippie 247 51 10 10 4
NCKAP1_ENST00000361354 NCKAP1 Q9Y2A7 Nck-associated protein 1 chr2 Not Cancer Driver No 4 intact, hippie, biogrid 129 44 3 3 0
NHSL2 NHSL2 Q5HYW2 NHS-like protein 2 chrX Not Cancer Driver No 2 intact, hippie, biogrid 123 1127 119 119 0
NTNG1_ENST00000370073 NTNG1 Q9Y2I2 Netrin-G1 chr1 Not Cancer Driver No 1 hippie, biogrid 149 1 0 0 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 Census, Compendium Yes 1 intact 249 57 21 21 0
OCLN OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 54 244 21 21 1
PACSIN1_ENST00000244458 PACSIN1 Q9BY11 Protein kinase C and casein kinase substrate in neurons protein 1 chr6 Not Cancer Driver No 1 hippie 56 318 47 47 0
PFN1 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 16 7 1 1 3
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 Census, Compendium Yes 1 hippie 179 214 31 31 2
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 intact, hippie 53 24 0 0 2
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
PSTPIP1 PSTPIP1 O43586 Proline-serine-threonine phosphatase-interacting protein 1 chr15 Not Cancer Driver No 1 hippie 46 225 26 26 3
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie, biogrid 31 43 4 4 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 intact, hippie 66 2 1 1 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 24 0 0 0 4
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie, biogrid 52 19 2 2 0
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 20 10 0 0 0
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 Not Cancer Driver No 1 hippie 55 85 4 4 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SORBS3 SORBS3 O60504 Vinexin chr8 Not Cancer Driver No 1 intact, hippie 62 577 56 56 0
SPG11 SPG11 Q96JI7 Spatacsin chr15 Not Cancer Driver No 1 hippie, biogrid 252 126 12 12 1
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 intact, hippie 71 194 35 35 2
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 29 164 14 14 0
TCERG1 TCERG1 O14776 Transcription elongation regulator 1 chr5 Not Cancer Driver No 1 hippie 143 811 110 110 0
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 1 hippie 141 662 136 136 13
TIMM50_ENST00000607714 TIMM50 Q3ZCQ8 Mitochondrial import inner membrane translocase subunit TIM50 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 39 75 7 7 0
TMEM17 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 22 14 2 2 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
VASP VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 1 hippie, biogrid 39 335 34 34 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WASF2 WASF2 Q9Y6W5 Wiskott-Aldrich syndrome protein family member 2 chr1 Not Cancer Driver No 1 hippie 61 400 43 43 0
WASHC3 WASHC3 Q9Y3C0 WASH complex subunit 3 chr12 Not Cancer Driver No 1 intact, hippie 29 100 8 8 0
WASL WASL O00401 Neural Wiskott-Aldrich syndrome protein chr7 Not Cancer Driver No 2 hippie, biogrid 72 394 57 57 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 2 intact, hippie, biogrid 22 109 4 4 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 hippie 29 41 6 6 0
ZDHHC17 ZDHHC17 Q8IUH5 Palmitoyltransferase ZDHHC17 chr12 Not Cancer Driver No 1 hippie 84 49 9 9 0
ZFPL1 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie, biogrid 40 127 16 16 0
ZNF511 ZNF511 Q8NB15 Zinc finger protein 511 chr10 Not Cancer Driver No 3 intact, hippie, biogrid 21 79 8 8 0