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VPS72 ,VPS72 ,Q15906
  • Uniprot Accession= Q15906
  • Ensembl Transcript= ENST00000354473.4
  • Uniprot Name= VPS72
  • Name= Vacuolar protein sorting-associated protein 72 homolog
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 46
  • Number of Interaction partner in biogrid: 65
  • Number of Interaction partner in hippie: 93
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTL6A ACTL6A O96019 Actin-like protein 6A chr3 Not Cancer Driver No 1 hippie 61 74 15 15 0
ACTR6 ACTR6 Q9GZN1 Actin-related protein 6 chr12 Not Cancer Driver No 1 intact, hippie 48 17 4 4 0
ANP32A ANP32A P39687 Acidic leucine-rich nuclear phosphoprotein 32 family member A chr15 Not Cancer Driver No 1 hippie, biogrid 31 165 21 21 0
ANP32B ANP32B Q92688 Acidic leucine-rich nuclear phosphoprotein 32 family member B chr9 Not Cancer Driver No 1 hippie, biogrid 22 117 12 12 0
ANP32E ANP32E Q9BTT0 Acidic leucine-rich nuclear phosphoprotein 32 family member E chr1 Not Cancer Driver No 1 hippie, biogrid 40 135 18 18 0
ATP6AP1 ATP6AP1 Q15904 V-type proton ATPase subunit S1 chrX Not Cancer Driver No 1 biogrid 67 0 0 0 4
ATP6V1G1 ATP6V1G1 O75348 V-type proton ATPase subunit G 1 chr9 Not Cancer Driver No 1 biogrid 12 91 8 8 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 17 112 9 9 0
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 Not Cancer Driver No 2 hippie, biogrid 189 934 147 147 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 intact, hippie 42 212 19 19 0
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 53 126 7 7 1
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 Not Cancer Driver No 1 hippie, biogrid 23 119 18 18 0
CCDC85B CCDC85B Q15834 Coiled-coil domain-containing protein 85B chr11 Not Cancer Driver No 1 intact, hippie 3 79 2 2 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 Census, Compendium Yes 1 hippie 12 342 12 12 1
CENPK_ENST00000514814 CENPK Q9BS16 Centromere protein K chr5 Not Cancer Driver No 1 biogrid 28 91 8 8 0
CHCHD4_ENST00000396914 CHCHD4 Q8N4Q1 Mitochondrial intermembrane space import and assembly protein 40 chr3 Not Cancer Driver No 1 hippie, biogrid 18 82 8 8 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 biogrid 284 1017 160 160 3
CMAS CMAS Q8NFW8 N-acylneuraminate cytidylyltransferase chr12 Not Cancer Driver No 1 biogrid 49 89 8 8 0
CSGALNACT1_ENST00000332246 CSGALNACT1 Q8TDX6 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 chr8 Not Cancer Driver No 1 hippie, biogrid 91 131 28 28 0
DMAP1_ENST00000315913 DMAP1 Q9NPF5 DNA methyltransferase 1-associated protein 1 chr1 Not Cancer Driver No 4 intact, hippie, biogrid 49 269 28 28 0
DONSON DONSON Q9NYP3 Protein downstream neighbor of Son chr21 Not Cancer Driver No 1 biogrid 50 217 13 13 6
E2F3 E2F3 O00716 Transcription factor E2F3 chr6 Not Cancer Driver No 1 intact, hippie 46 253 20 20 0
EAF1 EAF1 Q96JC9 ELL-associated factor 1 chr3 Not Cancer Driver No 1 hippie 17 257 17 17 0
EFR3A EFR3A Q14156 Protein EFR3 homolog A chr8 Not Cancer Driver No 1 biogrid 114 77 10 10 0
EIF3M EIF3M Q7L2H7 Eukaryotic translation initiation factor 3 subunit M chr11 Not Cancer Driver No 1 biogrid 44 0 0 0 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ELF1 ELF1 P32519 ETS-related transcription factor Elf-1 chr13 Not Cancer Driver No 1 hippie 78 469 62 62 0
ELF2 ELF2 Q15723 ETS-related transcription factor Elf-2 chr4 Not Cancer Driver No 1 intact, hippie 59 423 43 43 0
ELF3_ENST00000367283 ELF3 P78545 ETS-related transcription factor Elf-3 chr1 Census, Compendium Yes 1 intact, hippie 94 145 34 34 0
ELF4 ELF4 Q99607 ETS-related transcription factor Elf-4 chrX Census, Compendium Yes 1 intact, hippie 88 486 60 60 0
ELK3 ELK3 P41970 ETS domain-containing protein Elk-3 chr12 Not Cancer Driver No 1 intact, hippie 58 163 16 16 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EP400 EP400 Q96L91 E1A-binding protein p400 chr12 Not Cancer Driver No 1 hippie 397 2064 234 234 0
EPC1 EPC1 Q9H2F5 Enhancer of polycomb homolog 1 chr10 Not Cancer Driver No 2 intact, hippie 104 515 68 68 0
EPC2 EPC2 Q52LR7 Enhancer of polycomb homolog 2 chr2 Not Cancer Driver No 2 hippie, biogrid 95 583 67 67 0
ERH ERH P84090 Enhancer of rudimentary homolog chr14 Not Cancer Driver No 1 biogrid 7 11 0 0 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
ETV3 ETV3 P41162 ETS translocation variant 3 chr1 Not Cancer Driver No 1 intact, hippie 48 330 24 24 0
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 intact, hippie 94 646 93 93 0
FEV FEV Q99581 Protein FEV chr2 Census Yes 1 hippie 15 55 0 0 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX Not Cancer Driver No 1 intact, hippie 124 327 70 70 3
FOXR1 FOXR1 Q6PIV2 Forkhead box protein R1 chr11 Census Yes 3 intact, hippie, biogrid 43 153 26 26 0
FOXR2 FOXR2 Q6PJQ5 Forkhead box protein R2 chrX Not Cancer Driver No 3 intact, hippie, biogrid 79 128 41 41 0
GNL3L_ENST00000360845 GNL3L Q9NVN8 Guanine nucleotide-binding protein-like 3-like protein chrX Not Cancer Driver No 1 biogrid 120 242 43 43 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 Not Cancer Driver No 1 intact 23 71 16 16 0
HIST1H2BH H2BC9 Q93079 Histone H2B type 1-H chr6 Not Cancer Driver No 1 intact 42 79 20 20 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 55 319 41 41 0
HNF4A HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 Not Cancer Driver No 1 hippie 135 127 48 48 5
HSF2BP HSF2BP O75031 Heat shock factor 2-binding protein chr21 Not Cancer Driver No 1 intact, hippie 52 23 3 3 1
ING3 ING3 Q9NXR8 Inhibitor of growth protein 3 chr7 Not Cancer Driver No 1 hippie 44 292 32 32 1
ING5_ENST00000313552 ING5 Q8WYH8 Inhibitor of growth protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 25 119 9 9 0
INO80E INO80E Q8NBZ0 INO80 complex subunit E chr16 Not Cancer Driver No 1 hippie, biogrid 21 210 21 21 0
IRF8 IRF8 Q02556 Interferon regulatory factor 8 chr16 Not Cancer Driver No 1 intact, hippie 80 77 20 20 2
JAZF1 JAZF1 Q86VZ6 Juxtaposed with another zinc finger protein 1 chr7 Census Yes 1 hippie, biogrid 29 172 21 21 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 Not Cancer Driver No 5 intact, hippie, biogrid 65 173 21 21 3
KLF12 KLF12 Q9Y4X4 Krueppel-like factor 12 chr13 Not Cancer Driver No 1 hippie 60 338 50 50 0
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 Not Cancer Driver No 1 hippie 66 273 48 48 0
KLF16 KLF16 Q9BXK1 Krueppel-like factor 16 chr19 Not Cancer Driver No 1 intact, hippie 13 204 8 8 0
KLF3 KLF3 P57682 Krueppel-like factor 3 chr4 Not Cancer Driver No 1 intact, hippie 53 243 38 38 0
KLF6 KLF6 Q99612 Krueppel-like factor 6 chr10 Census Yes 1 hippie 47 139 26 26 0
KLF8 KLF8 O95600 Krueppel-like factor 8 chrX Not Cancer Driver No 1 intact, hippie 71 270 53 53 0
KPNA1 KPNA1 P52294 Importin subunit alpha-5 chr3 Not Cancer Driver No 1 intact, hippie 65 121 18 18 0
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 biogrid 74 611 69 69 0
LHX2 LHX2 P50458 LIM/homeobox protein Lhx2 chr9 Not Cancer Driver No 1 intact, hippie 60 203 28 28 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 Not Cancer Driver No 1 hippie, biogrid 26 12 1 1 0
MAGEA10 MAGEA10 P43363 Melanoma-associated antigen 10 chrX Not Cancer Driver No 2 hippie, biogrid 114 169 57 57 0
MAX MAX P61244 Protein max chr14 Census, Compendium Yes 2 hippie, biogrid 45 160 45 45 9
MBTD1_ENST00000415868 MBTD1 Q05BQ5 MBT domain-containing protein 1 chr17 Not Cancer Driver No 1 intact, hippie 66 119 8 8 0
MDFI MDFI Q99750 MyoD family inhibitor chr6 Not Cancer Driver No 1 hippie 25 152 15 15 0
MEAF6_ENST00000296214 MEAF6 Q9HAF1 Chromatin modification-related protein MEAF6 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 22 171 21 21 0
METAP2 METAP2 P50579 Methionine aminopeptidase 2 chr12 Not Cancer Driver No 1 biogrid 54 176 19 19 0
MORF4L1 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 Not Cancer Driver No 4 intact, hippie, biogrid 43 163 17 17 0
MORF4L2_ENST00000433176 MORF4L2 Q15014 Mortality factor 4-like protein 2 chrX Not Cancer Driver No 3 intact, hippie, biogrid 44 136 21 21 0
MRGBP MRGBP Q9NV56 MRG/MORF4L-binding protein chr20 Not Cancer Driver No 5 intact, hippie, biogrid 27 147 23 23 0
MYCL_ENST00000372816 MYCL P12524 Protein L-Myc chr1 Census Yes 2 intact, hippie, biogrid 47 275 43 43 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MZT1 MZT1 Q08AG7 Mitotic-spindle organizing protein 1 chr13 Not Cancer Driver No 1 biogrid 13 9 3 3 0
NFATC2IP NFATC2IP Q8NCF5 NFATC2-interacting protein chr16 Not Cancer Driver No 2 hippie, biogrid 41 330 29 29 0
NFIC NFIC P08651 Nuclear factor 1 C-type chr19 Not Cancer Driver No 1 hippie 61 327 44 44 0
NFIX_ENST00000592199 NFIX Q14938 Nuclear factor 1 X-type chr19 Not Cancer Driver No 1 intact, hippie 60 305 40 40 6
NFYC NFYC Q13952 Nuclear transcription factor Y subunit gamma chr1 Not Cancer Driver No 1 intact, hippie 46 320 32 32 0
NOL8_ENST00000442668 NOL8 Q76FK4 Nucleolar protein 8 chr9 Not Cancer Driver No 1 biogrid 127 978 109 109 0
P4HA3_ENST00000331597 P4HA3 Q7Z4N8 Prolyl 4-hydroxylase subunit alpha-3 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 70 17 2 2 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 Not Cancer Driver No 1 biogrid 42 82 11 11 7
PLAC1 PLAC1 Q9HBJ0 Placenta-specific protein 1 chrX Not Cancer Driver No 3 intact, hippie, biogrid 23 37 4 4 0
PLSCR4_ENST00000446574 PLSCR4 Q9NRQ2 Phospholipid scramblase 4 chr3 Not Cancer Driver No 1 hippie 68 108 11 11 0
POLR1E POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 Not Cancer Driver No 1 hippie, biogrid 39 85 6 6 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 1 hippie 41 12 1 1 8
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 Not Cancer Driver No 1 intact, hippie 50 18 1 1 0
PSMD1 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 biogrid 110 201 19 19 0
PSPH_ENST00000275605 PSPH P78330 Phosphoserine phosphatase chr7 Not Cancer Driver No 1 biogrid 44 21 6 6 3
QPRT QPRT Q15274 Nicotinate-nucleotide pyrophosphorylase [carboxylating] chr16 Not Cancer Driver No 3 intact, hippie, biogrid 29 7 1 1 0
RBM25 RBM25 P49756 RNA-binding protein 25 chr14 Not Cancer Driver No 1 biogrid 124 549 88 88 0
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 Not Cancer Driver No 5 intact, hippie, biogrid 54 67 7 7 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 5 intact, hippie, biogrid 62 100 13 13 0
S100P S100P P25815 Protein S100-P chr4 Not Cancer Driver No 1 hippie, biogrid 7 3 1 1 0
SET SET Q01105 Protein SET chr9 Census, Compendium Yes 1 hippie, biogrid 35 221 26 26 2
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 33 164 12 12 0
SLC35A1 SLC35A1 P78382 CMP-sialic acid transporter chr6 Not Cancer Driver No 1 biogrid 23 0 0 0 0
SLC39A9 SLC39A9 Q9NUM3 Zinc transporter ZIP9 chr14 Not Cancer Driver No 1 biogrid 34 44 4 4 0
SOX5 SOX5 P35711 Transcription factor SOX-5 chr12 Not Cancer Driver No 1 intact, hippie 182 665 162 162 0
SRCAP SRCAP Q6ZRS2 Helicase SRCAP chr16 Not Cancer Driver No 2 hippie, biogrid 438 2534 340 340 0
SRP19 SRP19 P09132 Signal recognition particle 19 kDa protein chr5 Not Cancer Driver No 1 biogrid 17 49 7 7 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 Census, Compendium Yes 1 intact, hippie 75 135 14 14 9
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 28 310 16 16 0
TET2 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 Census, Compendium Yes 1 hippie 191 1663 176 176 1
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 Census, Compendium Yes 1 hippie 120 537 61 61 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 Census, Compendium Yes 3 intact, hippie, biogrid 554 402 59 59 8
USE1 USE1 Q9NZ43 Vesicle transport protein USE1 chr19 Not Cancer Driver No 1 biogrid 31 101 19 19 0
WDR7 WDR7 Q9Y4E6 WD repeat-containing protein 7 chr18 Not Cancer Driver No 1 biogrid 199 292 37 37 0
YEATS4 YEATS4 O95619 YEATS domain-containing protein 4 chr12 Not Cancer Driver No 5 intact, hippie, biogrid 23 17 1 1 0
YTHDC1_ENST00000344157 YTHDC1 Q96MU7 YTH domain-containing protein 1 chr4 Not Cancer Driver No 1 biogrid 137 597 117 117 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 Not Cancer Driver No 1 hippie 37 336 26 26 2
ZFC3H1 ZFC3H1 O60293 Zinc finger C3H1 domain-containing protein chr12 Not Cancer Driver No 1 hippie, biogrid 210 1025 115 115 0
ZNHIT1 ZNHIT1 O43257 Zinc finger HIT domain-containing protein 1 chr7 Not Cancer Driver No 3 hippie, biogrid 34 85 16 16 0
ZXDB ZXDB P98169 Zinc finger X-linked protein ZXDB chrX Compendium Yes 1 hippie, biogrid 97 456 51 51 0