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VAV3 ,VAV3 ,Q9UKW4
  • Uniprot Accession= Q9UKW4
  • Ensembl Transcript= ENST00000370056.8
  • Uniprot Name= VAV3
  • Name= Guanine nucleotide exchange factor VAV3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 13
  • Number of Interaction partner in biogrid: 26
  • Number of Interaction partner in hippie: 53
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAMDC_ENST00000526415 AAMDC Q9H7C9 Mth938 domain-containing protein chr11 Not Cancer Driver No 1 hippie, biogrid 13 47 5 5 0
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 Census, Compendium Yes 1 intact, hippie 303 575 114 114 16
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 196 443 88 88 169
ATP5F1C ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 Not Cancer Driver No 1 hippie 39 11 0 0 0
BLNK BLNK Q8WV28 B-cell linker protein chr10 Not Cancer Driver No 2 intact, hippie 74 376 61 61 0
CA2 CA2 P00918 Carbonic anhydrase 2 chr8 Not Cancer Driver No 1 hippie, biogrid 41 55 8 8 4
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 Census Yes 1 hippie 160 562 104 104 0
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 Not Cancer Driver No 1 hippie, biogrid 85 495 61 61 0
CKAP4 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie, biogrid 73 409 55 55 0
CLCC1 CLCC1 Q96S66 Chloride channel CLIC-like protein 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 37 196 19 19 1
DDR1_ENST00000324771 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 Not Cancer Driver No 1 hippie 123 253 49 49 0
DDX42 DDX42 Q86XP3 ATP-dependent RNA helicase DDX42 chr17 Not Cancer Driver No 1 hippie, biogrid 126 607 79 79 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 2 hippie, biogrid 444 223 35 35 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 2 hippie, biogrid 275 314 41 41 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 2 hippie, biogrid 298 396 70 70 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 Census, Compendium Yes 1 hippie, biogrid 428 323 116 116 2
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
FAM76B FAM76B Q5HYJ3 Protein FAM76B chr11 Not Cancer Driver No 1 hippie, biogrid 38 194 23 23 0
FIP1L1 FIP1L1 Q6UN15 Pre-mRNA 3'-end-processing factor FIP1 chr4 Census Yes 1 hippie, biogrid 88 572 85 85 0
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 79 570 68 68 1
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 2 intact, hippie 28 10 1 1 0
GTF2F2 GTF2F2 P13984 General transcription factor IIF subunit 2 chr13 Not Cancer Driver No 1 intact, hippie 20 112 9 9 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie 183 265 37 37 6
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 hippie 190 280 57 57 64
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 Census, Compendium Yes 1 hippie, biogrid 226 83 33 33 21
LCP2 LCP2 Q13094 Lymphocyte cytosolic protein 2 chr5 Not Cancer Driver No 1 hippie 107 390 80 80 0
LUC7L2 LUC7L2 Q9Y383 Putative RNA-binding protein Luc7-like 2 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 59 262 45 45 0
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 101 128 22 22 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 intact, hippie, biogrid 226 62 15 15 19
NOP58 NOP58 Q9Y2X3 Nucleolar protein 58 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 47 156 14 14 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 Census, Compendium Yes 1 hippie 164 231 44 44 7
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 2 intact, hippie 154 268 61 61 2
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie 158 186 21 21 0
PSPC1_ENST00000619300 PSPC1 Q8WXF1 Paraspeckle component 1 chr13 Not Cancer Driver No 1 hippie, biogrid 97 367 81 81 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RBFOX2_ENST00000449924 RBFOX2 O43251 RNA binding protein fox-1 homolog 2 chr22 Compendium Yes 1 hippie, biogrid 44 173 22 22 0
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 Census, Compendium Yes 1 hippie, biogrid 118 686 91 91 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RINT1 RINT1 Q6NUQ1 RAD50-interacting protein 1 chr7 Not Cancer Driver No 1 hippie 84 55 3 3 2
ROS1 ROS1 P08922 Proto-oncogene tyrosine-protein kinase ROS chr6 Census Yes 1 hippie 498 191 55 55 0
SERPINH1_ENST00000358171 SERPINH1 P50454 Serpin H1 chr11 Not Cancer Driver No 1 hippie, biogrid 51 52 6 6 1
SH3BP2_ENST00000435136 SH3BP2 P78314 SH3 domain-binding protein 2 chr4 Not Cancer Driver No 2 intact, hippie 71 356 43 43 7
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie 84 397 58 58 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 hippie, biogrid 51 202 15 15 27
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 Not Cancer Driver No 1 hippie 70 285 33 33 0
TRAF1 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 Not Cancer Driver No 1 hippie 51 63 9 9 0
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 Compendium Yes 1 hippie 61 101 9 9 1
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 67 62 7 7 0
UBA52_ENST00000595683 UBA52 P62987 Ubiquitin-60S ribosomal protein L40 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 19 45 8 8 0
ZNF326 ZNF326 Q5BKZ1 DBIRD complex subunit ZNF326 chr1 Not Cancer Driver No 1 hippie, biogrid 64 490 53 53 0
ZRANB1 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 Not Cancer Driver No 1 hippie 87 158 25 25 0
ZYX ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie 83 385 52 52 0