Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABT1 | ABT1 | Q9ULW3 | Activator of basal transcription 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 157 | 30 | 30 | 0 |
AFDN_ENST00000447894 | AFDN | P55196 | Afadin | chr6 | Census | Yes | 1 | hippie | 248 | 1247 | 180 | 180 | 0 |
ANKRD36B | ANKRD36B | Q8N2N9 | Ankyrin repeat domain-containing protein 36B | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 803 | 39 | 39 | 0 |
ANLN | ANLN | Q9NQW6 | Anillin | chr7 | Not Cancer Driver | No | 1 | hippie | 144 | 767 | 104 | 104 | 2 |
APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | Not Cancer Driver | No | 1 | hippie | 34 | 103 | 14 | 14 | 0 |
ARF6 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 5 | 0 | 0 | 0 |
ARGLU1 | ARGLU1 | Q9NWB6 | Arginine and glutamate-rich protein 1 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 246 | 33 | 33 | 0 |
ATP2A1 | ATP2A1 | O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 80 | 11 | 11 | 1 |
B3GAT1_ENST00000312527 | B3GAT1 | Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 93 | 32 | 32 | 0 |
BCAP31_ENST00000345046 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 104 | 14 | 14 | 0 |
BET1 | BET1 | O15155 | BET1 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 14 | 7 | 2 | 2 | 0 |
BRAF | BRAF | P15056 | Serine/threonine-protein kinase B-raf | chr7 | Census, Compendium | Yes | 1 | hippie | 791 | 310 | 43 | 43 | 39 |
BRD2_ENST00000374831 | BRD2 | P25440 | Bromodomain-containing protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 108 | 632 | 85 | 85 | 0 |
BRD3 | BRD3 | Q15059 | Bromodomain-containing protein 3 | chr9 | Census | Yes | 1 | hippie | 87 | 566 | 68 | 68 | 0 |
C11orf52 | C11orf52 | Q96A22 | Uncharacterized protein C11orf52 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 108 | 12 | 12 | 0 |
CA9 | CA9 | Q16790 | Carbonic anhydrase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 72 | 274 | 50 | 50 | 0 |
CAMKV | CAMKV | Q8NCB2 | CaM kinase-like vesicle-associated protein | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 87 | 226 | 30 | 30 | 0 |
CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 2 | 0 | 0 | 0 |
CCDC8 | CCDC8 | Q9H0W5 | Coiled-coil domain-containing protein 8 | chr19 | Not Cancer Driver | No | 1 | hippie | 96 | 505 | 91 | 91 | 0 |
CD3E | CD3E | P07766 | T-cell surface glycoprotein CD3 epsilon chain | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 72 | 12 | 12 | 0 |
CD44 | CD44 | P16070 | CD44 antigen | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 75 | 542 | 60 | 60 | 0 |
CD6 | CD6 | P30203 | T-cell differentiation antigen CD6 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 91 | 268 | 41 | 41 | 0 |
CD82 | CD82 | P27701 | CD82 antigen | chr11 | Not Cancer Driver | No | 1 | hippie | 37 | 14 | 3 | 3 | 0 |
CD83 | CD83 | Q01151 | CD83 antigen | chr6 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 24 | 48 | 8 | 8 | 0 |
CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
CKAP4 | CKAP4 | Q07065 | Cytoskeleton-associated protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 409 | 55 | 55 | 0 |
COX8A | COX8A | P10176 | Cytochrome c oxidase subunit 8A, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 1 | 0 | 0 | 0 |
CREB3 | CREB3 | O43889 | Cyclic AMP-responsive element-binding protein 3 | chr9 | Not Cancer Driver | No | 1 | hippie | 33 | 168 | 11 | 11 | 0 |
CXADR | CXADR | P78310 | Coxsackievirus and adenovirus receptor | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 98 | 19 | 19 | 0 |
CYBC1_ENST00000577732 | CYBC1 | Q9BQA9 | Cytochrome b-245 chaperone 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 22 | 17 | 2 | 2 | 0 |
DERL1 | DERL1 | Q9BUN8 | Derlin-1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 11 | 1 | 1 | 0 |
DIRAS3_ENST00000646789 | DIRAS3 | O95661 | GTP-binding protein Di-Ras3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 21 | 3 | 3 | 0 |
DLG1_ENST00000419354 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 120 | 460 | 67 | 67 | 0 |
DNAJC1 | DNAJC1 | Q96KC8 | DnaJ homolog subfamily C member 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 315 | 44 | 44 | 0 |
DNAJC16 | DNAJC16 | Q9Y2G8 | DnaJ homolog subfamily C member 16 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 63 | 2 | 2 | 0 |
DNAJC25 | DNAJC25 | Q9H1X3 | DnaJ homolog subfamily C member 25 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 39 | 3 | 3 | 0 |
DNAJC5 | DNAJC5 | Q9H3Z4 | DnaJ homolog subfamily C member 5 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 46 | 6 | 6 | 1 |
DNAJC5B | DNAJC5B | Q9UF47 | DnaJ homolog subfamily C member 5B | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 31 | 7 | 7 | 0 |
DPP4 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 151 | 8 | 1 | 1 | 0 |
DVL1 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 73 | 434 | 38 | 38 | 0 |
DVL2 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 96 | 514 | 64 | 64 | 0 |
DVL3 | DVL3 | Q92997 | Segment polarity protein dishevelled homolog DVL-3 | chr3 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 97 | 437 | 58 | 58 | 0 |
DYRK2 | DYRK2 | Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 77 | 294 | 39 | 39 | 0 |
EBAG9_ENST00000620557 | EBAG9 | O00559 | Receptor-binding cancer antigen expressed on SiSo cells | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 173 | 29 | 29 | 0 |
EIF3L | EIF3L | Q9Y262 | Eukaryotic translation initiation factor 3 subunit L | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 41 | 1 | 1 | 0 |
ELOVL5_ENST00000304434 | ELOVL5 | Q9NYP7 | Elongation of very long chain fatty acids protein 5 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 25 | 4 | 4 | 2 |
EMD | EMD | P50402 | Emerin | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 42 | 160 | 28 | 28 | 4 |
EMP3_ENST00000597279 | EMP3 | P54852 | Epithelial membrane protein 3 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 0 | 0 | 0 | 0 |
EPB41L1 | EPB41L1 | Q9H4G0 | Band 4.1-like protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 151 | 577 | 109 | 109 | 1 |
EPB41L3 | EPB41L3 | Q9Y2J2 | Band 4.1-like protein 3 | chr18 | Not Cancer Driver | No | 2 | hippie, biogrid | 298 | 695 | 207 | 207 | 0 |
EPB41L4A_ENST00000621003 | EPB41L4A | Q9HCS5 | Band 4.1-like protein 4A | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 119 | 378 | 65 | 65 | 0 |
EPB41L5 | EPB41L5 | Q9HCM4 | Band 4.1-like protein 5 | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 97 | 312 | 45 | 45 | 0 |
ERBB4 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | Census, Compendium | Yes | 1 | hippie | 428 | 323 | 116 | 116 | 2 |
ERGIC1 | ERGIC1 | Q969X5 | Endoplasmic reticulum-Golgi intermediate compartment protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 26 | 2 | 2 | 0 |
ERMAP_ENST00000372514 | ERMAP | Q96PL5 | Erythroid membrane-associated protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 48 | 5 | 5 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
EVC2 | EVC2 | Q86UK5 | Limbin | chr4 | Not Cancer Driver | No | 1 | hippie | 240 | 335 | 71 | 71 | 2 |
EZR | EZR | P15311 | Ezrin | chr6 | Census | Yes | 1 | hippie, biogrid | 66 | 295 | 35 | 35 | 0 |
FBXL19 | FBXL19 | Q6PCT2 | F-box/LRR-repeat protein 19 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 350 | 38 | 38 | 0 |
FBXW11 | FBXW11 | Q9UKB1 | F-box/WD repeat-containing protein 11 | chr5 | Not Cancer Driver | No | 1 | hippie | 75 | 20 | 3 | 3 | 7 |
FGF8_ENST00000344255 | FGF8 | P55075 | Fibroblast growth factor 8 | chr10 | Not Cancer Driver | No | 2 | hippie, biogrid | 30 | 79 | 9 | 9 | 6 |
FGFBP1 | FGFBP1 | Q14512 | Fibroblast growth factor-binding protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 81 | 8 | 8 | 0 |
FKBP8_ENST00000222308 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 160 | 25 | 25 | 0 |
FLOT1 | FLOT1 | O75955 | Flotillin-1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 122 | 15 | 15 | 0 |
FMR1 | FMR1 | Q06787 | Synaptic functional regulator FMR1 | chrX | Not Cancer Driver | No | 1 | hippie | 124 | 327 | 70 | 70 | 3 |
GJA1 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 110 | 26 | 26 | 50 |
GJD3 | GJD3 | Q8N144 | Gap junction delta-3 protein | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 79 | 0 | 0 | 0 |
GMFG | GMFG | O60234 | Glia maturation factor gamma | chr19 | Not Cancer Driver | No | 1 | hippie | 22 | 10 | 0 | 0 | 0 |
GPR156_ENST00000315843 | GPR156 | Q8NFN8 | Probable G-protein coupled receptor 156 | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 131 | 417 | 74 | 74 | 0 |
HADHA | HADHA | P40939 | Trifunctional enzyme subunit alpha, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 19 | 2 | 2 | 5 |
HDGFL2 | HDGFL2 | Q7Z4V5 | Hepatoma-derived growth factor-related protein 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 59 | 622 | 57 | 57 | 0 |
HRAS | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | hippie | 107 | 16 | 4 | 4 | 18 |
HSD17B11 | HSD17B11 | Q8NBQ5 | Estradiol 17-beta-dehydrogenase 11 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 3 | 0 | 0 | 0 |
HSD3B7 | HSD3B7 | Q9H2F3 | 3 beta-hydroxysteroid dehydrogenase type 7 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 27 | 5 | 5 | 2 |
HSPA12A_ENST00000369209 | HSPA12A | O43301 | Heat shock 70 kDa protein 12A | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 130 | 86 | 16 | 16 | 0 |
HSPA12B | HSPA12B | Q96MM6 | Heat shock 70 kDa protein 12B | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 126 | 18 | 18 | 0 |
IL7R | IL7R | P16871 | Interleukin-7 receptor subunit alpha | chr5 | Census, Compendium | Yes | 1 | hippie, biogrid | 177 | 88 | 48 | 48 | 1 |
INAVA_ENST00000367342 | INAVA | Q3KP66 | Innate immunity activator protein | chr1 | Not Cancer Driver | No | 1 | hippie | 112 | 553 | 98 | 98 | 1 |
INO80E | INO80E | Q8NBZ0 | INO80 complex subunit E | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 210 | 21 | 21 | 0 |
JPH4_ENST00000356300 | JPH4 | Q96JJ6 | Junctophilin-4 | chr14 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 57 | 516 | 54 | 54 | 0 |
KBTBD7 | KBTBD7 | Q8WVZ9 | Kelch repeat and BTB domain-containing protein 7 | chr13 | Not Cancer Driver | No | 1 | hippie | 92 | 105 | 6 | 6 | 0 |
KCNE3 | KCNE3 | Q9Y6H6 | Potassium voltage-gated channel subfamily E member 3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 24 | 2 | 2 | 0 |
KIR2DL1 | KIR2DL1 | P43626 | Killer cell immunoglobulin-like receptor 2DL1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 112 | 135 | 44 | 44 | 0 |
KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 2 | hippie, biogrid | 788 | 7 | 2 | 2 | 27 |
LAMP1 | LAMP1 | P11279 | Lysosome-associated membrane glycoprotein 1 | chr13 | Not Cancer Driver | No | 2 | hippie, biogrid | 47 | 93 | 10 | 10 | 0 |
LAMP2_ENST00000200639 | LAMP2 | P13473 | Lysosome-associated membrane glycoprotein 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 55 | 7 | 7 | 1 |
LAMP3 | LAMP3 | Q9UQV4 | Lysosome-associated membrane glycoprotein 3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 222 | 38 | 38 | 0 |
LAMTOR1 | LAMTOR1 | Q6IAA8 | Ragulator complex protein LAMTOR1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 96 | 7 | 7 | 0 |
LCK | LCK | P06239 | Tyrosine-protein kinase Lck | chr1 | Census | Yes | 1 | hippie, biogrid | 86 | 94 | 13 | 13 | 1 |
LGALS1 | LGALS1 | P09382 | Galectin-1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 0 | 0 | 0 | 0 |
LGALS8_ENST00000366584 | LGALS8 | O00214 | Galectin-8 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 31 | 6 | 6 | 0 |
LMAN1 | LMAN1 | P49257 | Protein ERGIC-53 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 222 | 25 | 25 | 1 |
LNPK_ENST00000272748 | LNPK | Q9C0E8 | Endoplasmic reticulum junction formation protein lunapark | chr2 | Not Cancer Driver | No | 1 | hippie | 62 | 257 | 43 | 43 | 0 |
LRRC59 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 122 | 15 | 15 | 0 |
LUC7L | LUC7L | Q9NQ29 | Putative RNA-binding protein Luc7-like 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 254 | 41 | 41 | 0 |
LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | Census | Yes | 1 | hippie, biogrid | 95 | 84 | 12 | 12 | 0 |
MANSC1 | MANSC1 | Q9H8J5 | MANSC domain-containing protein 1 | chr12 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 53 | 206 | 21 | 21 | 0 |
MARCKS | MARCKS | P29966 | Myristoylated alanine-rich C-kinase substrate | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 328 | 14 | 14 | 0 |
MAST1 | MAST1 | Q9Y2H9 | Microtubule-associated serine/threonine-protein kinase 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 204 | 1078 | 119 | 119 | 1 |
METTL7A_ENST00000332160 | METTL7A | Q9H8H3 | Putative methyltransferase-like protein 7A | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 0 | 0 | 0 | 0 |
MYO6 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | Not Cancer Driver | No | 1 | hippie | 176 | 342 | 41 | 41 | 3 |
NAF1 | NAF1 | Q96HR8 | H/ACA ribonucleoprotein complex non-core subunit NAF1 | chr4 | Not Cancer Driver | No | 1 | hippie | 61 | 386 | 44 | 44 | 0 |
NBR1 | NBR1 | Q14596 | Next to BRCA1 gene 1 protein | chr17 | Not Cancer Driver | No | 1 | hippie | 101 | 560 | 51 | 51 | 0 |
NFKBIL1 | NFKBIL1 | Q9UBC1 | NF-kappa-B inhibitor-like protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 316 | 33 | 33 | 0 |
NRAS | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 284 | 10 | 0 | 0 | 14 |
NT5C3A | NT5C3A | Q9H0P0 | Cytosolic 5'-nucleotidase 3A | chr7 | Compendium | Yes | 1 | hippie | 44 | 0 | 0 | 0 | 8 |
NUAK2 | NUAK2 | B4E0Y5 | cDNA FLJ56013, highly similar to NUAK family SNF1-like kinase 2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 91 | 365 | 55 | 55 | 0 |
NXF2B | NXF2B | Q9GZY0 | Nuclear RNA export factor 2 | chrX | Not Cancer Driver | No | 1 | intact | 53 | 125 | 8 | 8 | 0 |
OCLN | OCLN | Q16625 | Occludin | chr5 | Not Cancer Driver | No | 1 | biogrid | 54 | 244 | 21 | 21 | 1 |
OTULINL | OTULINL | Q9NUU6 | Inactive ubiquitin thioesterase OTULINL | chr5 | Not Cancer Driver | No | 1 | hippie | 59 | 21 | 0 | 0 | 0 |
PANX1 | PANX1 | Q96RD7 | Pannexin-1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 45 | 7 | 7 | 2 |
PARD3 | PARD3 | Q8TEW0 | Partitioning defective 3 homolog | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 200 | 1144 | 170 | 170 | 2 |
PLCD3 | PLCD3 | Q8N3E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 229 | 22 | 22 | 0 |
PNN | PNN | Q9H307 | Pinin | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 94 | 700 | 90 | 90 | 0 |
PRG2 | PRG2 | P13727 | Bone marrow proteoglycan | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 65 | 15 | 15 | 0 |
PRICKLE3 | PRICKLE3 | O43900 | Prickle planar cell polarity protein 3 | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 76 | 276 | 33 | 33 | 1 |
PRKACA | PRKACA | P17612 | cAMP-dependent protein kinase catalytic subunit alpha | chr19 | Census | Yes | 1 | hippie, biogrid | 53 | 24 | 0 | 0 | 2 |
PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 140 | 25 | 25 | 0 |
PTPN3 | PTPN3 | P26045 | Tyrosine-protein phosphatase non-receptor type 3 | chr9 | Not Cancer Driver | No | 1 | hippie | 139 | 214 | 28 | 28 | 0 |
PXMP2 | PXMP2 | Q9NR77 | Peroxisomal membrane protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 0 | 0 | 0 | 0 |
RAB11A | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 43 | 4 | 4 | 0 |
RAB2A | RAB2A | P61019 | Ras-related protein Rab-2A | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 58 | 4 | 4 | 0 |
RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 25 | 2 | 2 | 0 |
RAB3B | RAB3B | P20337 | Ras-related protein Rab-3B | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 25 | 6 | 6 | 0 |
RAB4A | RAB4A | P20338 | Ras-related protein Rab-4A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 32 | 11 | 11 | 0 |
RAB5A | RAB5A | P20339 | Ras-related protein Rab-5A | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 65 | 15 | 15 | 0 |
RAB5C_ENST00000393860 | RAB5C | P51148 | Ras-related protein Rab-5C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 50 | 4 | 4 | 0 |
RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 1 | biogrid | 27 | 11 | 0 | 0 | 4 |
RAB9A | RAB9A | P51151 | Ras-related protein Rab-9A | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 21 | 1 | 1 | 0 |
RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 4 |
RAPGEF5_ENST00000401957 | RAPGEF5 | Q92565 | Rap guanine nucleotide exchange factor 5 | chr7 | Not Cancer Driver | No | 1 | hippie | 73 | 56 | 10 | 10 | 0 |
RASSF10 | RASSF10 | A6NK89 | Ras association domain-containing protein 10 | chr11 | Not Cancer Driver | No | 1 | hippie | 11 | 372 | 8 | 8 | 0 |
RASSF9 | RASSF9 | O75901 | Ras association domain-containing protein 9 | chr12 | Not Cancer Driver | No | 1 | hippie | 88 | 131 | 24 | 24 | 0 |
RHBDD1 | RHBDD1 | Q8TEB9 | Rhomboid-related protein 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 38 | 69 | 9 | 9 | 0 |
RHBDF2 | RHBDF2 | Q6PJF5 | Inactive rhomboid protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 93 | 284 | 36 | 36 | 2 |
RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 52 | 19 | 2 | 2 | 0 |
RHOC_ENST00000369642 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 53 | 7 | 7 | 0 |
RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 10 | 0 | 0 | 0 |
RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
RHOH_ENST00000617441 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 41 | 12 | 3 | 3 | 0 |
RHOJ | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
RHOQ | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | Not Cancer Driver | No | 1 | hippie | 25 | 0 | 0 | 0 | 0 |
RHOU | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 63 | 6 | 6 | 0 |
RHOV | RHOV | Q96L33 | Rho-related GTP-binding protein RhoV | chr15 | Not Cancer Driver | No | 1 | hippie | 25 | 47 | 5 | 5 | 0 |
RMDN3 | RMDN3 | Q96TC7 | Regulator of microtubule dynamics protein 3 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 196 | 17 | 17 | 0 |
RND1 | RND1 | Q92730 | Rho-related GTP-binding protein Rho6 | chr12 | Not Cancer Driver | No | 1 | hippie | 45 | 9 | 1 | 1 | 0 |
RND2 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | Not Cancer Driver | No | 1 | hippie | 19 | 54 | 4 | 4 | 0 |
RND3_ENST00000263895 | RND3 | P61587 | Rho-related GTP-binding protein RhoE | chr2 | Not Cancer Driver | No | 1 | hippie | 36 | 70 | 10 | 10 | 0 |
RNF41_ENST00000615206 | RNF41 | Q9H4P4 | E3 ubiquitin-protein ligase NRDP1 | chr12 | Not Cancer Driver | No | 1 | hippie | 44 | 33 | 2 | 2 | 0 |
RNPS1_ENST00000301730 | RNPS1 | Q15287 | RNA-binding protein with serine-rich domain 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 305 | 30 | 30 | 0 |
RP9 | RP9 | Q8TA86 | Retinitis pigmentosa 9 protein | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 206 | 23 | 23 | 2 |
RPL22 | RPL22 | P35268 | 60S ribosomal protein L22 | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 26 | 15 | 1 | 1 | 0 |
RPN1 | RPN1 | P04843 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | chr3 | Census | Yes | 1 | hippie, biogrid | 50 | 69 | 3 | 3 | 0 |
RPN2 | RPN2 | P04844 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 26 | 4 | 4 | 0 |
RPS24_ENST00000613865 | RPS24 | P62847 | 40S ribosomal protein S24 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 88 | 10 | 10 | 0 |
RPS6KA2_ENST00000265678 | RPS6KA2 | Q15349 | Ribosomal protein S6 kinase alpha-2 | chr6 | Not Cancer Driver | No | 1 | hippie | 133 | 91 | 15 | 15 | 0 |
SAP18_ENST00000607003 | SAP18 | O00422 | Histone deacetylase complex subunit SAP18 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 99 | 14 | 14 | 0 |
SDC1_ENST00000254351 | SDC1 | P18827 | Syndecan-1 | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 31 | 259 | 30 | 30 | 0 |
SDC2 | SDC2 | P34741 | Syndecan-2 | chr8 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 41 | 127 | 24 | 24 | 0 |
SDC4 | SDC4 | P31431 | Syndecan-4 | chr20 | Census, Compendium | Yes | 1 | hippie, biogrid | 34 | 110 | 25 | 25 | 0 |
SEC61B | SEC61B | P60468 | Protein transport protein Sec61 subunit beta | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 11 | 60 | 7 | 7 | 0 |
SEC62 | SEC62 | Q99442 | Translocation protein SEC62 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 211 | 23 | 23 | 0 |
SEC63 | SEC63 | Q9UGP8 | Translocation protein SEC63 homolog | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 98 | 266 | 37 | 37 | 0 |
SIDT2_ENST00000620360 | SIDT2 | Q8NBJ9 | SID1 transmembrane family member 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 113 | 23 | 6 | 6 | 0 |
SLC25A46 | SLC25A46 | Q96AG3 | Mitochondrial outer membrane protein SLC25A46 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 96 | 2 | 2 | 4 |
SMYD3 | SMYD3 | Q9H7B4 | Histone-lysine N-methyltransferase SMYD3 | chr1 | Not Cancer Driver | No | 1 | hippie | 59 | 2 | 0 | 0 | 0 |
SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 169 | 29 | 29 | 1 |
SRPK1 | SRPK1 | Q96SB4 | SRSF protein kinase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 73 | 329 | 32 | 32 | 0 |
SSR1 | SSR1 | P43307 | Translocon-associated protein subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 114 | 10 | 10 | 0 |
ST7 | ST7 | Q9NRC1 | Suppressor of tumorigenicity 7 protein | chr7 | Not Cancer Driver | No | 1 | hippie | 62 | 64 | 5 | 5 | 0 |
STIM1_ENST00000300737 | STIM1 | Q13586 | Stromal interaction molecule 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 387 | 45 | 45 | 13 |
STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 152 | 20 | 20 | 0 |
STX6 | STX6 | O43752 | Syntaxin-6 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 78 | 11 | 11 | 0 |
STX7 | STX7 | O15400 | Syntaxin-7 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 164 | 14 | 14 | 0 |
SYNJ2BP | SYNJ2BP | P57105 | Synaptojanin-2-binding protein | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 12 | 4 | 4 | 0 |
SYT12_ENST00000527043 | SYT12 | Q8IV01 | Synaptotagmin-12 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 73 | 13 | 13 | 0 |
TCTN3 | TCTN3 | Q6NUS6 | Tectonic-3 | chr10 | Not Cancer Driver | No | 1 | hippie | 45 | 71 | 8 | 8 | 1 |
TGOLN2_ENST00000377386 | TGOLN2 | O43493 | Trans-Golgi network integral membrane protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 51 | 399 | 46 | 46 | 0 |
THAP2 | THAP2 | Q9H0W7 | THAP domain-containing protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 22 | 41 | 3 | 3 | 0 |
TMEM17 | TMEM17 | Q86X19 | Transmembrane protein 17 | chr2 | Not Cancer Driver | No | 1 | hippie | 22 | 14 | 2 | 2 | 0 |
TMEM216 | TMEM216 | Q9P0N5 | Transmembrane protein 216 | chr11 | Not Cancer Driver | No | 1 | hippie | 11 | 0 | 0 | 0 | 7 |
TMPO | TMPO | P42166 | Lamina-associated polypeptide 2, isoform alpha | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 412 | 52 | 52 | 0 |
TNFRSF1A | TNFRSF1A | P19438 | Tumor necrosis factor receptor superfamily member 1A | chr12 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 58 | 111 | 15 | 15 | 12 |
TNFRSF1B | TNFRSF1B | P20333 | Tumor necrosis factor receptor superfamily member 1B | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 229 | 28 | 28 | 0 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TYROBP | TYROBP | O43914 | TYRO protein tyrosine kinase-binding protein | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 28 | 8 | 8 | 0 |
U2AF2 | U2AF2 | P26368 | Splicing factor U2AF 65 kDa subunit | chr19 | Compendium | Yes | 1 | hippie, biogrid | 78 | 191 | 28 | 28 | 0 |
VANGL2 | VANGL2 | Q9ULK5 | Vang-like protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 122 | 150 | 37 | 37 | 3 |
VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 186 | 16 | 16 | 16 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
ZC3H18_ENST00000301011 | ZC3H18 | Q86VM9 | Zinc finger CCCH domain-containing protein 18 | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 139 | 929 | 134 | 134 | 0 |
ZCCHC10 | ZCCHC10 | Q8TBK6 | Zinc finger CCHC domain-containing protein 10 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 144 | 11 | 11 | 0 |
ZFPL1 | ZFPL1 | O95159 | Zinc finger protein-like 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 127 | 16 | 16 | 0 |
ZNF385C | ZNF385C | Q66K41 | Zinc finger protein 385C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 260 | 15 | 15 | 0 |
ZRANB2 | ZRANB2 | O95218 | Zinc finger Ran-binding domain-containing protein 2 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 56 | 257 | 44 | 44 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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