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VAMP4 ,VAMP4 ,O75379
  • Uniprot Accession= O75379
  • Ensembl Transcript= ENST00000236192.11
  • Uniprot Name= VAMP4
  • Name= Vesicle-associated membrane protein 4
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 67
  • Number of Interaction partner in biogrid: 74
  • Number of Interaction partner in hippie: 132
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AC004754.1 FAM234A B4DGG1 Protein FAM234A chr16 Not Cancer Driver No 1 hippie 56 69 9 9 0
ANKFY1_ENST00000341657 ANKFY1 Q9P2R3 Rabankyrin-5 chr17 Not Cancer Driver No 1 hippie, biogrid 109 185 29 29 0
ANKS6 ANKS6 Q68DC2 Ankyrin repeat and SAM domain-containing protein 6 chr9 Not Cancer Driver No 1 intact, hippie 94 568 60 60 2
AP1B1 AP1B1 Q10567 AP-1 complex subunit beta-1 chr22 Not Cancer Driver No 1 hippie 114 119 10 10 1
AP1M1_ENST00000291439 AP1M1 Q9BXS5 AP-1 complex subunit mu-1 chr19 Not Cancer Driver No 1 hippie 64 38 12 12 0
AP1S3_ENST00000446015 AP1S3 Q96PC3 AP-1 complex subunit sigma-3 chr2 Not Cancer Driver No 1 intact, hippie 27 0 0 0 2
AP2B1_ENST00000621914 AP2B1 P63010 AP-2 complex subunit beta chr17 Not Cancer Driver No 1 hippie, biogrid 85 95 12 12 0
AQP6_ENST00000315520 AQP6 Q13520 Aquaporin-6 chr12 Not Cancer Driver No 1 intact, hippie 48 22 4 4 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
ARL13B ARL13B Q3SXY8 ADP-ribosylation factor-like protein 13B chr3 Not Cancer Driver No 1 intact, hippie 62 251 40 40 3
B3GAT1_ENST00000312527 B3GAT1 Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 85 93 32 32 0
BCL2L13_ENST00000317582 BCL2L13 Q9BXK5 Bcl-2-like protein 13 chr22 Not Cancer Driver No 1 hippie 49 291 30 30 0
BNIP1_ENST00000351486 BNIP1 Q12981 Vesicle transport protein SEC20 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 43 57 10 10 0
C19orf25 C19orf25 Q9UFG5 UPF0449 protein C19orf25 chr19 Not Cancer Driver No 1 hippie, biogrid 6 117 6 6 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
CCDC155 KASH5 Q8N6L0 Protein KASH5 chr19 Not Cancer Driver No 1 intact 88 401 70 70 0
CISD2 CISD2 Q8N5K1 CDGSH iron-sulfur domain-containing protein 2 chr4 Not Cancer Driver No 1 hippie 11 7 0 0 0
CLEC12A_ENST00000304361 CLEC12A Q5QGZ9 C-type lectin domain family 12 member A chr12 Not Cancer Driver No 2 intact, hippie, biogrid 41 9 3 3 0
CLINT1_ENST00000411809 CLINT1 Q14677 Clathrin interactor 1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 61 475 51 51 0
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 15 23 6 6 2
CPLX4 CPLX4 Q7Z7G2 Complexin-4 chr18 Not Cancer Driver No 1 hippie 36 142 33 33 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 hippie 71 75 8 8 4
CYB5R3_ENST00000352397 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie 42 24 3 3 9
CZIB CZIB Q9NWV4 CXXC motif containing zinc binding protein chr1 Not Cancer Driver No 1 intact, hippie 19 2 1 1 0
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie, biogrid 44 37 2 2 0
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 Not Cancer Driver No 1 intact, hippie 23 46 6 6 1
EBAG9_ENST00000620557 EBAG9 O00559 Receptor-binding cancer antigen expressed on SiSo cells chr8 Not Cancer Driver No 1 hippie, biogrid 35 173 29 29 0
EBP EBP Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase chrX Not Cancer Driver No 1 intact, hippie 30 9 0 0 9
ELOVL4 ELOVL4 Q9GZR5 Elongation of very long chain fatty acids protein 4 chr6 Not Cancer Driver No 1 hippie 68 23 6 6 1
ELOVL5_ENST00000304434 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 Not Cancer Driver No 1 hippie, biogrid 34 25 4 4 2
ERGIC2 ERGIC2 Q96RQ1 Endoplasmic reticulum-Golgi intermediate compartment protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 37 25 2 2 0
ERGIC3_ENST00000348547 ERGIC3 Q9Y282 Endoplasmic reticulum-Golgi intermediate compartment protein 3 chr20 Not Cancer Driver No 1 hippie 53 23 3 3 0
EVI2B_ENST00000577894 EVI2B P34910 Protein EVI2B chr17 Not Cancer Driver No 1 intact, hippie 63 373 55 55 0
FAM209A FAM209A Q5JX71 Protein FAM209A chr20 Not Cancer Driver No 1 intact, hippie 30 53 7 7 0
FAM210B FAM210B Q96KR6 Protein FAM210B, mitochondrial chr20 Not Cancer Driver No 1 intact, hippie 10 32 0 0 0
FAM234A_ENST00000301678 FAM234A Q9H0X4 Protein FAM234A chr16 Not Cancer Driver No 1 hippie 60 99 11 11 0
FAM234B FAM234B A2RU67 Protein FAM234B chr12 Not Cancer Driver No 1 hippie 91 136 26 26 0
GALM GALM Q96C23 Galactose mutarotase chr2 Not Cancer Driver No 1 intact, hippie, biogrid 31 35 2 2 1
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 86 110 26 26 50
GJD3 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 5 79 0 0 0
GLE1 GLE1 Q53GS7 mRNA export factor GLE1 chr9 Not Cancer Driver No 1 intact, hippie 64 299 29 29 3
GOLGA1 GOLGA1 Q92805 Golgin subfamily A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 99 582 77 77 0
GOSR1 GOSR1 O95249 Golgi SNAP receptor complex member 1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 26 108 11 11 0
GOSR2_ENST00000640051 GOSR2 O14653 Golgi SNAP receptor complex member 2 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 25 103 17 17 1
GPR152 GPR152 Q8TDT2 Probable G-protein coupled receptor 152 chr11 Not Cancer Driver No 1 intact, hippie 55 172 27 27 0
GPX8 GPX8 Q8TED1 Probable glutathione peroxidase 8 chr5 Not Cancer Driver No 1 intact, hippie 21 4 1 1 0
HECTD4 HECTD4 J3KPF0 Probable E3 ubiquitin-protein ligase HECTD4 chr12 Not Cancer Driver No 2 intact, biogrid 469 1062 134 134 0
HS6ST2_ENST00000406696 HS6ST2 Q96MM7 Heparan-sulfate 6-O-sulfotransferase 2 chrX Not Cancer Driver No 1 hippie, biogrid 77 184 20 20 0
ITFG1 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie, biogrid 70 18 3 3 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 intact, hippie, biogrid 788 7 2 2 27
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 47 93 10 10 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie, biogrid 43 55 7 7 1
LAMP3 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 67 222 38 38 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LDLRAD1 LDLRAD1 Q5T700 Low-density lipoprotein receptor class A domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 28 14 2 2 0
LEUTX_ENST00000638280 LEUTX A8MZ59 Paired-like homeodomain transcription factor LEUTX chr19 Not Cancer Driver No 1 intact, hippie 7 120 3 3 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 2 intact, hippie 68 544 49 49 131
LSMEM2 LSMEM2 Q8N112 Leucine-rich single-pass membrane protein 2 chr3 Not Cancer Driver No 1 hippie, biogrid 22 34 3 3 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 hippie 10 17 1 1 0
MBLAC2 MBLAC2 Q68D91 Acyl-coenzyme A thioesterase MBLAC2 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 16 1 0 0 0
METTL7A_ENST00000332160 METTL7A Q9H8H3 Putative methyltransferase-like protein 7A chr12 Not Cancer Driver No 1 hippie, biogrid 31 0 0 0 0
MFF MFF Q9GZY8 Mitochondrial fission factor chr2 Not Cancer Driver No 1 intact, hippie 59 264 47 47 0
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
MTIF3_ENST00000381120 MTIF3 Q9H2K0 Translation initiation factor IF-3, mitochondrial chr13 Not Cancer Driver No 1 intact, hippie 26 180 19 19 0
NAPA NAPA P54920 Alpha-soluble NSF attachment protein chr19 Not Cancer Driver No 2 hippie, biogrid 33 11 0 0 0
NAPB_ENST00000377026 NAPB Q9H115 Beta-soluble NSF attachment protein chr20 Not Cancer Driver No 2 intact, hippie, biogrid 30 29 2 2 0
NAPG NAPG Q99747 Gamma-soluble NSF attachment protein chr18 Not Cancer Driver No 3 intact, hippie, biogrid 35 56 3 3 0
NBAS NBAS A2RRP1 NBAS subunit of NRZ tethering complex chr2 Not Cancer Driver No 2 intact, hippie, biogrid 365 246 41 41 5
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
NSF NSF P46459 Vesicle-fusing ATPase chr17 Not Cancer Driver No 1 hippie, biogrid 47 84 3 3 2
NTMT1_ENST00000613644 NTMT1 Q9BV86 N-terminal Xaa-Pro-Lys N-methyltransferase 1 chr9 Not Cancer Driver No 2 hippie, biogrid 27 1 0 0 0
OXSM OXSM Q9NWU1 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie, biogrid 62 44 6 6 0
PACS1 PACS1 Q6VY07 Phosphofurin acidic cluster sorting protein 1 chr11 Not Cancer Driver No 1 hippie 121 511 65 65 1
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 87 119 13 13 0
PSCA PSCA O43653 Prostate stem cell antigen chr8 Not Cancer Driver No 1 hippie 9 0 0 0 0
PTGES PTGES O14684 Prostaglandin E synthase chr9 Not Cancer Driver No 1 intact, hippie 10 0 0 0 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie, biogrid 31 43 4 4 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 22 58 4 4 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RAB4A RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 26 32 11 11 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 32 65 15 15 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 24 50 4 4 0
RAB9A RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 1 hippie, biogrid 18 21 1 1 0
REEP4 REEP4 Q9H6H4 Receptor expression-enhancing protein 4 chr8 Not Cancer Driver No 1 intact, hippie 27 90 15 15 0
RETREG3 RETREG3 Q86VR2 Reticulophagy regulator 3 chr17 Not Cancer Driver No 1 intact, hippie 42 248 29 29 0
RINT1 RINT1 Q6NUQ1 RAD50-interacting protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 84 55 3 3 2
SAR1A_ENST00000373238 SAR1A Q9NR31 GTP-binding protein SAR1a chr10 Not Cancer Driver No 1 intact, hippie 23 4 0 0 0
SCAMP5_ENST00000425597 SCAMP5 Q8TAC9 Secretory carrier-associated membrane protein 5 chr15 Not Cancer Driver No 1 intact, hippie 41 2 1 1 0
SCFD1 SCFD1 Q8WVM8 Sec1 family domain-containing protein 1 chr14 Not Cancer Driver No 2 hippie, biogrid 66 117 12 12 0
SCFD2 SCFD2 Q8WU76 Sec1 family domain-containing protein 2 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 96 24 4 4 0
SEC11C SEC11C Q9BY50 Signal peptidase complex catalytic subunit SEC11C chr18 Not Cancer Driver No 1 intact, hippie 24 3 0 0 0
SERPINB8 SERPINB8 P50452 Serpin B8 chr18 Not Cancer Driver No 1 hippie, biogrid 74 4 0 0 0
SLC10A6 SLC10A6 Q3KNW5 Solute carrier family 10 member 6 chr4 Not Cancer Driver No 1 hippie 61 38 7 7 0
SLITRK3 SLITRK3 O94933 SLIT and NTRK-like protein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 335 321 127 127 0
SNAP23 SNAP23 O00161 Synaptosomal-associated protein 23 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 18 179 16 16 0
SNAP29 SNAP29 O95721 Synaptosomal-associated protein 29 chr22 Not Cancer Driver No 2 hippie, biogrid 21 246 20 20 0
SNAP47_ENST00000366759 SNAP47 Q5SQN1 Synaptosomal-associated protein 47 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 51 192 20 20 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 intact, hippie 71 194 35 35 2
SSMEM1 SSMEM1 Q8WWF3 Serine-rich single-pass membrane protein 1 chr7 Not Cancer Driver No 1 intact, hippie 45 181 32 32 0
STOM STOM P27105 Stomatin chr9 Not Cancer Driver No 1 intact, hippie 23 44 3 3 0
STX10 STX10 O60499 Syntaxin-10 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 29 77 7 7 0
STX11 STX11 O75558 Syntaxin-11 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 71 48 7 7 0
STX12 STX12 Q86Y82 Syntaxin-12 chr1 Not Cancer Driver No 4 intact, hippie, biogrid 21 156 9 9 0
STX16 STX16 O14662 Syntaxin-16 chr20 Not Cancer Driver No 3 intact, hippie, biogrid 45 120 12 12 0
STX18 STX18 Q9P2W9 Syntaxin-18 chr4 Not Cancer Driver No 3 hippie, biogrid 28 174 15 15 0
STX1A STX1A Q16623 Syntaxin-1A chr7 Not Cancer Driver No 1 hippie 35 136 11 11 0
STX3 STX3 Q13277 Syntaxin-3 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 51 129 30 30 0
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 3 hippie, biogrid 50 152 20 20 0
STX5 STX5 Q13190 Syntaxin-5 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 36 147 14 14 0
STX6 STX6 O43752 Syntaxin-6 chr1 Not Cancer Driver No 6 intact, hippie, biogrid 33 78 11 11 0
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 5 intact, hippie, biogrid 29 164 14 14 0
STX8 STX8 Q9UNK0 Syntaxin-8 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 32 98 10 10 0
SYT2_ENST00000367268 SYT2 Q8N9I0 Synaptotagmin-2 chr1 Not Cancer Driver No 1 intact, hippie 73 141 24 24 3
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 intact, hippie 51 399 46 46 0
TM4SF19 TM4SF19 Q96DZ7 Transmembrane 4 L6 family member 19 chr3 Not Cancer Driver No 1 hippie 27 0 0 0 0
TMEM17 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 22 14 2 2 0
TMEM205 TMEM205 Q6UW68 Transmembrane protein 205 chr19 Not Cancer Driver No 1 intact, hippie 20 19 4 4 0
TMEM51_ENST00000376014 TMEM51 Q9NW97 Transmembrane protein 51 chr1 Not Cancer Driver No 1 intact, hippie 47 181 37 37 0
TMEM59 TMEM59 Q9BXS4 Transmembrane protein 59 chr1 Not Cancer Driver No 1 hippie, biogrid 39 26 3 3 0
TMX2 TMX2 Q9Y320 Thioredoxin-related transmembrane protein 2 chr11 Not Cancer Driver No 1 hippie 47 40 5 5 3
TNFRSF10C TNFRSF10C O14798 Tumor necrosis factor receptor superfamily member 10C chr8 Not Cancer Driver No 1 hippie, biogrid 47 120 30 30 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 Not Cancer Driver No 1 intact, hippie 154 543 46 46 0
TRIM54_ENST00000380075 TRIM54 Q9BYV2 Tripartite motif-containing protein 54 chr2 Not Cancer Driver No 1 hippie, biogrid 63 98 17 17 0
USE1 USE1 Q9NZ43 Vesicle transport protein USE1 chr19 Not Cancer Driver No 2 hippie, biogrid 31 101 19 19 0
VPS45_ENST00000644510 VPS45 Q9NRW7 Vacuolar protein sorting-associated protein 45 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 66 57 5 5 2
VPS50 VPS50 Q96JG6 Syndetin chr7 Not Cancer Driver No 1 intact, hippie 175 171 32 32 0
VPS51 VPS51 Q9UID3 Vacuolar protein sorting-associated protein 51 homolog chr11 Not Cancer Driver No 1 intact, hippie 75 150 11 11 1
VPS52 VPS52 Q8N1B4 Vacuolar protein sorting-associated protein 52 homolog chr6 Not Cancer Driver No 1 hippie 89 36 5 5 0
VPS53 VPS53 Q5VIR6 Vacuolar protein sorting-associated protein 53 homolog chr17 Not Cancer Driver No 1 hippie 83 172 27 27 1
VTI1A VTI1A Q96AJ9 Vesicle transport through interaction with t-SNAREs homolog 1A chr10 Census Yes 3 intact, hippie, biogrid 21 138 13 13 0
VTI1B VTI1B Q9UEU0 Vesicle transport through interaction with t-SNAREs homolog 1B chr14 Not Cancer Driver No 3 hippie, biogrid 25 192 20 20 0
ZFPL1 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie, biogrid 40 127 16 16 0
ZNF526 ZNF526 Q8TF50 Zinc finger protein 526 chr19 Not Cancer Driver No 1 intact, hippie 86 421 56 56 0
ZW10 ZW10 O43264 Centromere/kinetochore protein zw10 homolog chr11 Not Cancer Driver No 1 intact, hippie, biogrid 90 63 11 11 0