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USP33_ENST00000357428 ,USP33 ,Q8TEY7
  • Uniprot Accession= Q8TEY7
  • Ensembl Transcript= ENST00000357428.5
  • Uniprot Name= USP33
  • Name= Ubiquitin carboxyl-terminal hydrolase 33
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 10
  • Number of Interaction partner in biogrid: 75
  • Number of Interaction partner in hippie: 115
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 Not Cancer Driver No 1 hippie 52 35 4 4 0
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
APBA2_ENST00000561069 APBA2 Q99767 Amyloid-beta A4 precursor protein-binding family A member 2 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 184 429 117 117 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 Not Cancer Driver No 1 hippie 49 154 13 13 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie 46 122 22 22 0
ASIC5 ASIC5 Q9NY37 Acid-sensing ion channel 5 chr4 Not Cancer Driver No 1 hippie, biogrid 112 12 4 4 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 157 80 11 11 1
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 hippie 36 178 21 21 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie, biogrid 37 104 14 14 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 Not Cancer Driver No 1 hippie 45 190 19 19 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 80 45 4 4 0
CGRRF1 CGRRF1 Q99675 Cell growth regulator with RING finger domain protein 1 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 31 34 5 5 0
CHRM5 CHRM5 P08912 Muscarinic acetylcholine receptor M5 chr15 Not Cancer Driver No 1 hippie 74 155 20 20 0
CKAP4 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie, biogrid 73 409 55 55 0
CRAMP1 CRAMP1 Q96RY5 Protein cramped-like chr16 Not Cancer Driver No 1 hippie 120 991 94 94 0
CT55 CT55 Q8WUE5 Cancer/testis antigen 55 chrX Not Cancer Driver No 1 hippie, biogrid 42 40 3 3 0
CTAG2 CTAG2 O75638 Cancer/testis antigen 2 chrX Not Cancer Driver No 1 hippie, biogrid 54 198 52 52 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
DDX56 DDX56 Q9NY93 Probable ATP-dependent RNA helicase DDX56 chr7 Not Cancer Driver No 1 hippie, biogrid 50 107 13 13 0
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 28 11 1 1 0
DIO2_ENST00000557010 DIO2 Q92813 Type II iodothyronine deiodinase chr14 Not Cancer Driver No 1 hippie 73 44 4 4 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 hippie 132 514 82 82 0
DNAJC1 DNAJC1 Q96KC8 DnaJ homolog subfamily C member 1 chr10 Not Cancer Driver No 1 hippie, biogrid 60 315 44 44 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 Not Cancer Driver No 1 hippie 31 7 0 0 0
EBAG9_ENST00000620557 EBAG9 O00559 Receptor-binding cancer antigen expressed on SiSo cells chr8 Not Cancer Driver No 1 hippie, biogrid 35 173 29 29 0
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 Not Cancer Driver No 1 hippie 54 141 5 5 0
EIF6_ENST00000374436 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 Not Cancer Driver No 1 hippie, biogrid 30 17 3 3 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ELOB_ENST00000409906 ELOB Q15370 Elongin-B chr16 Not Cancer Driver No 1 hippie 13 69 10 10 0
ELOC ELOC Q15369 Elongin-C chr8 Not Cancer Driver No 1 hippie 22 25 5 5 0
ELOVL5_ENST00000304434 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 Not Cancer Driver No 1 hippie, biogrid 34 25 4 4 2
EMD EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 42 160 28 28 4
EXOC2 EXOC2 Q96KP1 Exocyst complex component 2 chr6 Not Cancer Driver No 1 hippie 105 134 18 18 0
GABRG2_ENST00000639213 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 Not Cancer Driver No 1 hippie, biogrid 188 19 13 13 11
GCGR GCGR P47871 Glucagon receptor chr17 Not Cancer Driver No 1 hippie 16 56 2 2 4
GJD3 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 5 79 0 0 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 Not Cancer Driver No 1 hippie, biogrid 42 11 0 0 1
GPR17 GPR17 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor chr2 Not Cancer Driver No 1 hippie, biogrid 57 16 4 4 0
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 Census, Compendium Yes 1 hippie, biogrid 528 506 207 207 31
HERC2 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 Compendium Yes 1 hippie 718 971 150 150 1
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 107 16 4 4 18
HSD17B11 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 28 3 0 0 0
HSD3B7 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 43 27 5 5 2
IFIT5 IFIT5 Q13325 Interferon-induced protein with tetratricopeptide repeats 5 chr10 Not Cancer Driver No 1 hippie, biogrid 43 19 0 0 0
IL17RA IL17RA Q96F46 Interleukin-17 receptor A chr22 Not Cancer Driver No 1 hippie, biogrid 92 301 20 20 0
IL32 IL32 P24001 Interleukin-32 chr16 Not Cancer Driver No 1 hippie, biogrid 41 70 17 17 0
ITGB3BP_ENST00000271002 ITGB3BP Q13352 Centromere protein R chr1 Not Cancer Driver No 1 hippie 19 122 14 14 0
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 Not Cancer Driver No 1 hippie, biogrid 96 82 16 16 5
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie, biogrid 788 7 2 2 27
KRR1 KRR1 Q13601 KRR1 small subunit processome component homolog chr12 Not Cancer Driver No 1 hippie, biogrid 37 194 23 23 0
KRT27 KRT27 Q7Z3Y8 Keratin, type I cytoskeletal 27 chr17 Not Cancer Driver No 1 hippie, biogrid 80 142 28 28 0
LDLRAD4 LDLRAD4 O15165 Low-density lipoprotein receptor class A domain-containing protein 4 chr18 Not Cancer Driver No 1 hippie, biogrid 66 191 39 39 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie, biogrid 68 544 49 49 131
LPCAT4 LPCAT4 Q643R3 Lysophospholipid acyltransferase LPCAT4 chr15 Not Cancer Driver No 2 hippie, biogrid 52 92 10 10 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
LRRN2_ENST00000367177 LRRN2 O75325 Leucine-rich repeat neuronal protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 132 84 18 18 0
LRRTM1 LRRTM1 Q86UE6 Leucine-rich repeat transmembrane neuronal protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 172 57 17 17 0
MCOLN2 MCOLN2 Q8IZK6 Mucolipin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 93 0 0 0 0
METTL7A_ENST00000332160 METTL7A Q9H8H3 Putative methyltransferase-like protein 7A chr12 Not Cancer Driver No 1 hippie, biogrid 31 0 0 0 0
MPPED1_ENST00000443721 MPPED1 O15442 Metallophosphoesterase domain-containing protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 79 26 15 15 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NEURL4 NEURL4 Q96JN8 Neuralized-like protein 4 chr17 Not Cancer Driver No 1 hippie 217 751 119 119 0
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
NUP155 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie, biogrid 154 221 19 19 1
OCIAD1 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 37 169 25 25 0
OTULINL OTULINL Q9NUU6 Inactive ubiquitin thioesterase OTULINL chr5 Not Cancer Driver No 1 hippie 59 21 0 0 0
PCGF6 PCGF6 Q9BYE7 Polycomb group RING finger protein 6 chr10 Not Cancer Driver No 2 hippie, biogrid 29 142 11 11 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRPF38B PRPF38B Q5VTL8 Pre-mRNA-splicing factor 38B chr1 Not Cancer Driver No 1 hippie, biogrid 70 387 52 52 0
PXMP2 PXMP2 Q9NR77 Peroxisomal membrane protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 15 0 0 0 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 32 65 15 15 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 biogrid 27 11 0 0 4
RALA RALA P11233 Ras-related protein Ral-A chr7 Not Cancer Driver No 1 hippie 34 34 3 3 5
RALB RALB P11234 Ras-related protein Ral-B chr2 Not Cancer Driver No 1 hippie 36 35 5 5 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 30 53 7 7 0
ROBO1 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 Not Cancer Driver No 1 hippie 353 1122 234 234 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie, biogrid 50 69 3 3 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 53 26 4 4 0
RXFP1_ENST00000307765 RXFP1 Q9HBX9 Relaxin receptor 1 chr4 Not Cancer Driver No 1 hippie, biogrid 152 0 0 0 0
SAMM50 SAMM50 Q9Y512 Sorting and assembly machinery component 50 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 51 34 1 1 0
SEC61B SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 2 hippie, biogrid 11 60 7 7 0
SEC62 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 41 211 23 23 0
SELENBP1_ENST00000368868 SELENBP1 Q13228 Methanethiol oxidase chr1 Not Cancer Driver No 1 intact, hippie 67 32 5 5 2
SKP2 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 52 52 6 6 0
SLC25A46 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 Not Cancer Driver No 1 hippie, biogrid 37 96 2 2 4
SPA17 SPA17 Q15506 Sperm surface protein Sp17 chr11 Not Cancer Driver No 2 hippie, biogrid 18 137 15 15 0
SPINT2 SPINT2 O43291 Kunitz-type protease inhibitor 2 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 46 25 3 3 1
SPSB4 SPSB4 Q96A44 SPRY domain-containing SOCS box protein 4 chr3 Not Cancer Driver No 1 hippie, biogrid 42 75 3 3 0
SSR1 SSR1 P43307 Translocon-associated protein subunit alpha chr6 Not Cancer Driver No 1 hippie, biogrid 26 114 10 10 0
ST7 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie 62 64 5 5 0
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 hippie, biogrid 70 387 45 45 13
STN1 STN1 Q9H668 CST complex subunit STN1 chr10 Not Cancer Driver No 2 intact, hippie 41 27 2 2 2
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 20 20 0
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
TKTL2 TKTL2 Q9H0I9 Transketolase-like protein 2 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 196 70 23 23 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 Not Cancer Driver No 2 hippie, biogrid 108 0 0 0 0
TMEM134 TMEM134 Q9H6X4 Transmembrane protein 134 chr11 Not Cancer Driver No 1 hippie, biogrid 8 72 0 0 0
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie, biogrid 78 412 52 52 0
TMX1 TMX1 Q9H3N1 Thioredoxin-related transmembrane protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 34 59 6 6 0
TPTE2 TPTE2 Q6XPS3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 chr13 Not Cancer Driver No 1 hippie, biogrid 210 33 13 13 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 67 62 7 7 0
TRIM54_ENST00000380075 TRIM54 Q9BYV2 Tripartite motif-containing protein 54 chr2 Not Cancer Driver No 1 hippie 63 98 17 17 0
TRIM63 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 Not Cancer Driver No 1 hippie 47 71 13 13 0
TRPC3_ENST00000264811 TRPC3 Q13507 Short transient receptor potential channel 3 chr4 Not Cancer Driver No 1 hippie, biogrid 200 23 2 2 1
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 Not Cancer Driver No 1 hippie 136 259 39 39 0
USP20_ENST00000358355 USP20 Q9Y2K6 Ubiquitin carboxyl-terminal hydrolase 20 chr9 Not Cancer Driver No 1 hippie 112 295 36 36 0
USP21_ENST00000289865 USP21 Q9UK80 Ubiquitin carboxyl-terminal hydrolase 21 chr1 Not Cancer Driver No 1 hippie 95 230 47 47 0
USP28 USP28 Q96RU2 Ubiquitin carboxyl-terminal hydrolase 28 chr11 Not Cancer Driver No 1 hippie 151 311 25 25 0
VAPA_ENST00000400000 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 2 intact, hippie, biogrid 24 184 14 14 0
VAPB VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 Not Cancer Driver No 3 intact, hippie, biogrid 16 138 8 8 3
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 142 117 36 36 133
VSX2 VSX2 P58304 Visual system homeobox 2 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 43 268 23 23 5
ZDHHC12 ZDHHC12 Q96GR4 Palmitoyltransferase ZDHHC12 chr9 Not Cancer Driver No 1 hippie, biogrid 23 13 1 1 0
ZFR ZFR Q96KR1 Zinc finger RNA-binding protein chr5 Not Cancer Driver No 1 hippie, biogrid 121 594 71 71 0
ZNRF4 ZNRF4 Q8WWF5 E3 ubiquitin-protein ligase ZNRF4 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 115 99 26 26 0