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USP1_ENST00000371146 ,USP1 ,O94782
  • Uniprot Accession= O94782
  • Ensembl Transcript= ENST00000371146.5
  • Uniprot Name= USP1
  • Name= Ubiquitin carboxyl-terminal hydrolase 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 23
  • Number of Interaction partner in biogrid: 42
  • Number of Interaction partner in hippie: 95
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
ALDH16A1 ALDH16A1 Q8IZ83 Aldehyde dehydrogenase family 16 member A1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 90 175 26 26 0
ANAPC1 ANAPC1 Q9H1A4 Anaphase-promoting complex subunit 1 chr2 Not Cancer Driver No 1 hippie 206 263 33 33 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 Not Cancer Driver No 1 hippie 200 1075 112 112 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 Not Cancer Driver No 1 hippie 98 861 79 79 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BCR BCR P11274 Breakpoint cluster region protein chr22 Census, Compendium Yes 1 hippie 146 603 69 69 0
CALML3 CALML3 P27482 Calmodulin-like protein 3 chr10 Not Cancer Driver No 1 hippie, biogrid 34 105 28 28 0
CALML5 CALML5 Q9NZT1 Calmodulin-like protein 5 chr10 Not Cancer Driver No 1 hippie, biogrid 34 98 21 21 0
CAPNS1 CAPNS1 P04632 Calpain small subunit 1 chr19 Not Cancer Driver No 1 hippie 30 58 5 5 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CERK CERK Q8TCT0 Ceramide kinase chr22 Not Cancer Driver No 1 intact, hippie 56 48 5 5 0
CHIC1 CHIC1 Q5VXU3 Cysteine-rich hydrophobic domain-containing protein 1 chrX Not Cancer Driver No 1 hippie, biogrid 15 93 9 9 0
CIRBP_ENST00000586472 CIRBP Q14011 Cold-inducible RNA-binding protein chr19 Not Cancer Driver No 1 hippie, biogrid 19 129 13 13 0
CSE1L CSE1L P55060 Exportin-2 chr20 Not Cancer Driver No 1 hippie, biogrid 109 32 5 5 0
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 Not Cancer Driver No 1 hippie 48 94 4 4 0
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 hippie 151 65 9 9 0
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DSC1 DSC1 Q08554 Desmocollin-1 chr18 Not Cancer Driver No 1 intact, hippie, biogrid 219 265 65 65 0
DSG1 DSG1 Q02413 Desmoglein-1 chr18 Not Cancer Driver No 1 hippie, biogrid 250 496 130 130 0
DTX3_ENST00000337737 DTX3 Q8N9I9 Probable E3 ubiquitin-protein ligase DTX3 chr12 Not Cancer Driver No 1 hippie 58 182 31 31 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
EZR EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie 66 295 35 35 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FANCI FANCI Q9NVI1 Fanconi anemia group I protein chr15 Not Cancer Driver No 1 hippie 161 129 20 20 2
FLG FLG P20930 Filaggrin chr1 Not Cancer Driver No 1 intact, hippie, biogrid 1612 3956 1593 1593 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 67 283 26 26 2
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 10 118 8 8 20
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 Not Cancer Driver No 1 hippie 14 52 7 7 0
JUP JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 1 intact, hippie, biogrid 112 241 37 37 0
KATNA1 KATNA1 O75449 Katanin p60 ATPase-containing subunit A1 chr6 Not Cancer Driver No 1 hippie 66 199 30 30 0
KLHDC2 KLHDC2 Q9Y2U9 Kelch domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie 39 42 2 2 0
KPNA1 KPNA1 P52294 Importin subunit alpha-5 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 65 121 18 18 0
KPNA2_ENST00000330459 KPNA2 P52292 Importin subunit alpha-1 chr17 Not Cancer Driver No 1 hippie, biogrid 74 129 18 18 0
KPNA3 KPNA3 O00505 Importin subunit alpha-4 chr13 Not Cancer Driver No 1 hippie 65 108 11 11 0
KPNA5 KPNA5 O15131 Importin subunit alpha-6 chr6 Not Cancer Driver No 1 hippie 65 133 13 13 0
KPNA7 KPNA7 A9QM74 Importin subunit alpha-8 chr7 Not Cancer Driver No 1 hippie 36 66 2 2 0
KPNB1 KPNB1 Q14974 Importin subunit beta-1 chr17 Not Cancer Driver No 1 hippie 92 94 11 11 0
KRT17 KRT17 Q04695 Keratin, type I cytoskeletal 17 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 86 160 31 31 18
KRT4 KRT4 P19013 Keratin, type II cytoskeletal 4 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 116 130 23 23 1
LRRC15_ENST00000347624 LRRC15 Q8TF66 Leucine-rich repeat-containing protein 15 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 124 37 11 11 0
LYZ LYZ P61626 Lysozyme C chr12 Not Cancer Driver No 1 intact, hippie, biogrid 26 0 0 0 2
MGARP MGARP Q8TDB4 Protein MGARP chr4 Not Cancer Driver No 1 hippie, biogrid 25 207 22 22 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie, biogrid 310 1120 160 160 17
NFAT5_ENST00000354436 NFAT5 O94916 Nuclear factor of activated T-cells 5 chr16 Not Cancer Driver No 1 hippie 142 1307 119 119 0
NMRAL1 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 39 14 3 3 0
OPALIN OPALIN Q96PE5 Opalin chr10 Not Cancer Driver No 1 hippie, biogrid 29 86 18 18 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 hippie 30 22 3 3 1
PHF7 PHF7 Q9BWX1 PHD finger protein 7 chr3 Not Cancer Driver No 1 hippie 44 62 5 5 0
PHLPP1 PHLPP1 O60346 PH domain leucine-rich repeat-containing protein phosphatase 1 chr18 Not Cancer Driver No 4 intact, hippie, biogrid 134 744 29 29 0
PHLPP2 PHLPP2 Q6ZVD8 PH domain leucine-rich repeat-containing protein phosphatase 2 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 157 309 37 37 0
PKP1 PKP1 Q13835 Plakophilin-1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 106 190 26 26 0
PTGES2 PTGES2 Q9H7Z7 Prostaglandin E synthase 2 chr9 Not Cancer Driver No 1 hippie, biogrid 30 30 1 1 0
RAD51AP1 RAD51AP1 Q96B01 RAD51-associated protein 1 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 46 335 43 43 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 Compendium Yes 1 hippie 82 277 39 39 4
RPS16 RPS16 P62249 40S ribosomal protein S16 chr19 Not Cancer Driver No 1 hippie 16 14 1 1 0
RPS18 RPS18 P62269 40S ribosomal protein S18 chr6 Not Cancer Driver No 1 hippie 28 27 8 8 0
RPS4X RPS4X P62701 40S ribosomal protein S4, X isoform chrX Not Cancer Driver No 1 hippie 32 35 6 6 0
RSRP1 RSRP1 Q9BUV0 Arginine/serine-rich protein 1 chr1 Not Cancer Driver No 1 intact, hippie 23 284 23 23 0
SGO1 SGO1 Q5FBB7 Shugoshin 1 chr3 Not Cancer Driver No 1 hippie 57 360 39 39 1
SGTB SGTB Q96EQ0 Small glutamine-rich tetratricopeptide repeat-containing protein beta chr5 Not Cancer Driver No 1 hippie 28 114 10 10 0
SHPRH SHPRH Q149N8 E3 ubiquitin-protein ligase SHPRH chr6 Not Cancer Driver No 1 hippie 227 359 51 51 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 Census, Compendium Yes 1 hippie 49 144 25 25 8
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 52 97 11 11 0
SOCS6_ENST00000582322 SOCS6 O14544 Suppressor of cytokine signaling 6 chr18 Not Cancer Driver No 2 hippie, biogrid 81 299 48 48 0
SORT1 SORT1 Q99523 Sortilin chr1 Not Cancer Driver No 1 intact, hippie 69 110 2 2 0
SPANXN2 SPANXN2 Q5MJ10 Sperm protein associated with the nucleus on the X chromosome N2 chrX Not Cancer Driver No 1 hippie, biogrid 106 180 106 106 0
SPANXN5 SPANXN5 Q5MJ07 Sperm protein associated with the nucleus on the X chromosome N5 chrX Not Cancer Driver No 1 hippie, biogrid 27 72 27 27 0
STAT2 STAT2 P52630 Signal transducer and activator of transcription 2 chr12 Not Cancer Driver No 2 hippie, biogrid 90 178 22 22 2
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 Not Cancer Driver No 1 hippie 93 285 39 39 0
TAGLN2_ENST00000368097 TAGLN2 P37802 Transgelin-2 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 28 83 12 12 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 1 hippie 101 42 5 5 12
TOR1AIP1_ENST00000606911 TOR1AIP1 Q5JTV8 Torsin-1A-interacting protein 1 chr1 Not Cancer Driver No 1 intact, hippie 71 401 44 44 0
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 Compendium Yes 1 hippie 61 101 9 9 1
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 67 62 7 7 0
TRIM46 TRIM46 Q7Z4K8 Tripartite motif-containing protein 46 chr1 Not Cancer Driver No 1 hippie 115 173 30 30 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX Compendium Yes 1 hippie, biogrid 35 67 13 13 2
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 Not Cancer Driver No 1 hippie 24 33 3 3 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 Not Cancer Driver No 1 hippie 142 588 77 77 0
UNC45A UNC45A Q9H3U1 Protein unc-45 homolog A chr15 Not Cancer Driver No 1 hippie, biogrid 78 128 4 4 0
USP12 USP12 O75317 Ubiquitin carboxyl-terminal hydrolase 12 chr13 Not Cancer Driver No 1 hippie, biogrid 55 33 5 5 0
USP1_ENST00000371146 USP1 O94782 Ubiquitin carboxyl-terminal hydrolase 1 chr1 Not Cancer Driver No 1 hippie 63 403 30 30 0
USP4 USP4 Q13107 Ubiquitin carboxyl-terminal hydrolase 4 chr3 Not Cancer Driver No 1 hippie, biogrid 102 286 22 22 0
USP43 USP43 Q70EL4 Ubiquitin carboxyl-terminal hydrolase 43 chr17 Not Cancer Driver No 1 intact, hippie 134 562 56 56 0
USP46 USP46 P62068 Ubiquitin carboxyl-terminal hydrolase 46 chr4 Not Cancer Driver No 1 hippie, biogrid 48 28 4 4 0
VPS26A_ENST00000263559 VPS26A O75436 Vacuolar protein sorting-associated protein 26A chr10 Not Cancer Driver No 1 hippie, biogrid 27 44 2 2 0
VPS36 VPS36 Q86VN1 Vacuolar protein-sorting-associated protein 36 chr13 Not Cancer Driver No 1 hippie, biogrid 35 94 14 14 0
WDR20_ENST00000342702 WDR20 Q8TBZ3 WD repeat-containing protein 20 chr14 Not Cancer Driver No 1 hippie, biogrid 56 209 26 26 0
WDR48 WDR48 Q8TAF3 WD repeat-containing protein 48 chr3 Not Cancer Driver No 5 intact, hippie, biogrid 61 125 19 19 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
ZCCHC10 ZCCHC10 Q8TBK6 Zinc finger CCHC domain-containing protein 10 chr5 Not Cancer Driver No 1 hippie, biogrid 12 144 11 11 0