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URB2 ,URB2 ,Q14146
  • Uniprot Accession= Q14146
  • Ensembl Transcript= ENST00000258243.6
  • Uniprot Name= URB2
  • Name= Unhealthy ribosome biogenesis protein 2 homolog
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 18
  • Number of Interaction partner in biogrid: 56
  • Number of Interaction partner in hippie: 85
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABT1 ABT1 Q9ULW3 Activator of basal transcription 1 chr6 Not Cancer Driver No 1 hippie, biogrid 56 157 30 30 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
ANOS1 ANOS1 P23352 Anosmin-1 chrX Not Cancer Driver No 1 hippie 124 195 44 44 14
APLNR APLNR P35414 Apelin receptor chr11 Not Cancer Driver No 1 hippie, biogrid 96 29 8 8 0
APOBEC3C APOBEC3C Q9NRW3 DNA dC->dU-editing enzyme APOBEC-3C chr22 Not Cancer Driver No 1 hippie, biogrid 28 2 0 0 0
AQP3 AQP3 Q92482 Aquaporin-3 chr9 Not Cancer Driver No 1 hippie, biogrid 34 12 0 0 0
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX Not Cancer Driver No 1 intact, hippie 56 0 0 0 2
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
CCDC59 CCDC59 Q9P031 Thyroid transcription factor 1-associated protein 26 chr12 Not Cancer Driver No 2 hippie, biogrid 34 206 27 27 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 48 53 6 6 1
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 Not Cancer Driver No 1 hippie, biogrid 72 342 30 30 0
DGCR2 DGCR2 P98153 Integral membrane protein DGCR2/IDD chr22 Not Cancer Driver No 1 hippie, biogrid 90 178 24 24 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 Not Cancer Driver No 1 hippie, biogrid 59 188 22 22 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 45 2 0 0 0
FGF3 FGF3 P11487 Fibroblast growth factor 3 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 40 104 24 24 2
FGFBP1 FGFBP1 Q14512 Fibroblast growth factor-binding protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 28 81 8 8 0
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 Census, Compendium Yes 1 hippie 100 295 53 53 0
GPR182 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 49 33 4 4 0
GYPA_ENST00000360771 GYPA P02724 Glycophorin-A chr4 Not Cancer Driver No 1 hippie, biogrid 46 94 31 31 0
H2AFY2 MACROH2A2 Q9P0M6 Core histone macro-H2A.2 chr10 Not Cancer Driver No 1 intact 59 171 32 32 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie 155 419 90 90 0
ILF3_ENST00000590261 ILF3 Q12906 Interleukin enhancer-binding factor 3 chr19 Not Cancer Driver No 1 hippie, biogrid 103 674 82 82 0
ILVBL ILVBL A1L0T0 2-hydroxyacyl-CoA lyase 2 chr19 Not Cancer Driver No 1 hippie, biogrid 86 30 1 1 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LMNB1 LMNB1 P20700 Lamin-B1 chr5 Not Cancer Driver No 1 hippie 60 404 42 42 4
MAGEB2 MAGEB2 O15479 Melanoma-associated antigen B2 chrX Not Cancer Driver No 1 hippie, biogrid 98 126 35 35 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX Not Cancer Driver No 2 intact, hippie, biogrid 75 483 74 74 46
MGARP MGARP Q8TDB4 Protein MGARP chr4 Not Cancer Driver No 1 hippie, biogrid 25 207 22 22 0
MNDA MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 Not Cancer Driver No 1 intact, hippie, biogrid 180 172 76 76 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NIFK NIFK Q9BYG3 MKI67 FHA domain-interacting nucleolar phosphoprotein chr2 Not Cancer Driver No 1 hippie, biogrid 32 148 15 15 0
NOL8_ENST00000442668 NOL8 Q76FK4 Nucleolar protein 8 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 127 978 109 109 0
NOP2_ENST00000322166 NOP2 P46087 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase chr12 Not Cancer Driver No 1 hippie, biogrid 116 510 72 72 0
NOP56 NOP56 O00567 Nucleolar protein 56 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 83 191 34 34 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OPALIN OPALIN Q96PE5 Opalin chr10 Not Cancer Driver No 1 hippie, biogrid 29 86 18 18 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 Not Cancer Driver No 2 intact, hippie, biogrid 107 58 27 27 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 119 320 34 34 0
PLEC PLEC Q15149 Plectin chr8 Not Cancer Driver No 1 intact, hippie 677 2130 272 272 2
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 Not Cancer Driver No 1 hippie, biogrid 41 104 12 12 1
RBM34 RBM34 P42696 RNA-binding protein 34 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 50 267 34 34 0
RBM4_ENST00000310092 RBM4 Q9BWF3 RNA-binding protein 4 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 40 129 12 12 0
REXO4 REXO4 Q9GZR2 RNA exonuclease 4 chr9 Not Cancer Driver No 1 hippie, biogrid 34 298 26 26 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RPL13A RPL13A P40429 60S ribosomal protein L13a chr19 Not Cancer Driver No 1 hippie, biogrid 27 33 2 2 0
RPL13_ENST00000393099 RPL13 P26373 60S ribosomal protein L13 chr16 Not Cancer Driver No 1 hippie, biogrid 14 160 11 11 1
RPL14_ENST00000396203 RPL14 P50914 60S ribosomal protein L14 chr3 Not Cancer Driver No 1 hippie, biogrid 21 129 13 13 0
RPL15_ENST00000413699 RPL15 P61313 60S ribosomal protein L15 chr3 Not Cancer Driver No 1 hippie, biogrid 18 84 9 9 0
RPL18A RPL18A Q02543 60S ribosomal protein L18a chr19 Not Cancer Driver No 2 intact, hippie, biogrid 28 25 4 4 0
RPL23A RPL23A P62750 60S ribosomal protein L23a chr17 Not Cancer Driver No 1 hippie, biogrid 21 70 13 13 0
RPL28_ENST00000559463 RPL28 P46779 60S ribosomal protein L28 chr19 Not Cancer Driver No 1 hippie, biogrid 29 115 24 24 0
RPL3 RPL3 P39023 60S ribosomal protein L3 chr22 Not Cancer Driver No 1 hippie, biogrid 34 79 3 3 0
RPL31_ENST00000264258 RPL31 P62899 60S ribosomal protein L31 chr2 Not Cancer Driver No 1 hippie, biogrid 19 69 14 14 0
RPL36_ENST00000347512 RPL36 Q9Y3U8 60S ribosomal protein L36 chr19 Not Cancer Driver No 1 hippie, biogrid 7 66 4 4 0
RPL4 RPL4 P36578 60S ribosomal protein L4 chr15 Not Cancer Driver No 1 hippie, biogrid 49 222 31 31 0
RPLP0_ENST00000228306 RPLP0 P05388 60S acidic ribosomal protein P0 chr12 Not Cancer Driver No 1 hippie, biogrid 44 36 4 4 0
RPS24_ENST00000613865 RPS24 P62847 40S ribosomal protein S24 chr10 Not Cancer Driver No 1 hippie, biogrid 13 88 10 10 0
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 Not Cancer Driver No 1 hippie, biogrid 38 150 25 25 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 intact, hippie 74 513 48 48 0
RRP8 RRP8 O43159 Ribosomal RNA-processing protein 8 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 66 270 44 44 0
SCN3B_ENST00000299333 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 63 16 5 5 3
SCP2 SCP2 P22307 Sterol carrier protein 2 chr1 Not Cancer Driver No 1 hippie 59 45 2 2 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 Not Cancer Driver No 2 hippie, biogrid 82 64 10 10 0
SORT1 SORT1 Q99523 Sortilin chr1 Not Cancer Driver No 1 intact, hippie 69 110 2 2 0
SPSB4 SPSB4 Q96A44 SPRY domain-containing SOCS box protein 4 chr3 Not Cancer Driver No 1 hippie, biogrid 42 75 3 3 0
SRPK1 SRPK1 Q96SB4 SRSF protein kinase 1 chr6 Not Cancer Driver No 1 hippie, biogrid 73 329 32 32 0
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 Not Cancer Driver No 2 hippie, biogrid 78 343 46 46 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
TAX1BP1 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 Not Cancer Driver No 1 hippie 78 429 50 50 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VSIG1_ENST00000217957 VSIG1 Q86XK7 V-set and immunoglobulin domain-containing protein 1 chrX Not Cancer Driver No 2 hippie, biogrid 55 137 20 20 0
WDR89 WDR89 Q96FK6 WD repeat-containing protein 89 chr14 Not Cancer Driver No 1 hippie, biogrid 33 56 4 4 0
ZNF330 ZNF330 Q9Y3S2 Zinc finger protein 330 chr4 Not Cancer Driver No 1 hippie, biogrid 44 127 19 19 0
ZNF467 ZNF467 Q7Z7K2 Zinc finger protein 467 chr7 Not Cancer Driver No 1 hippie, biogrid 75 345 37 37 0
ZNF48 ZNF48 Q96MX3 Zinc finger protein 48 chr16 Not Cancer Driver No 1 hippie, biogrid 87 516 78 78 0
ZNF512 ZNF512 Q96ME7 Zinc finger protein 512 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 76 280 42 42 0