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UQCRH ,UQCRH ,P07919
  • Uniprot Accession= P07919
  • Ensembl Transcript= ENST00000311672.9
  • Uniprot Name= UQCRH
  • Name= Cytochrome b-c1 complex subunit 6, mitochondrial
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 39
  • Number of Interaction partner in biogrid: 85
  • Number of Interaction partner in hippie: 124
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTR10 ACTR10 Q9NZ32 Actin-related protein 10 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 45 29 3 3 0
ACTR1B ACTR1B P42025 Beta-centractin chr2 Not Cancer Driver No 2 intact, hippie, biogrid 59 17 4 4 0
ADCK5 ADCK5 Q3MIX3 Uncharacterized aarF domain-containing protein kinase 5 chr8 Not Cancer Driver No 1 hippie 51 5 2 2 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 intact, hippie 88 166 22 22 11
ALDOA_ENST00000643777 ALDOA P04075 Fructose-bisphosphate aldolase A chr16 Not Cancer Driver No 1 intact 47 65 9 9 3
APOE APOE P02649 Apolipoprotein E chr19 Not Cancer Driver No 1 hippie, biogrid 25 124 6 6 12
ARL8A ARL8A Q96BM9 ADP-ribosylation factor-like protein 8A chr1 Not Cancer Driver No 2 intact, hippie 23 0 0 0 0
ARMCX3_ENST00000537169 ARMCX3 Q9UH62 Armadillo repeat-containing X-linked protein 3 chrX Not Cancer Driver No 1 hippie, biogrid 39 77 7 7 0
ASPH ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 Not Cancer Driver No 1 hippie, biogrid 109 373 53 53 1
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATP13A3_ENST00000256031 ATP13A3 Q9H7F0 Polyamine-transporting ATPase 13A3 chr3 Not Cancer Driver No 1 hippie, biogrid 149 49 11 11 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 157 80 11 11 1
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 Not Cancer Driver No 1 hippie, biogrid 136 78 14 14 41
ATP2A3_ENST00000397041 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 Not Cancer Driver No 1 hippie, biogrid 130 147 16 16 0
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 60 85 8 8 0
ATP6V0D1 ATP6V0D1 P61421 V-type proton ATPase subunit d 1 chr16 Not Cancer Driver No 1 hippie, biogrid 40 0 0 0 0
ATP6V1B2 ATP6V1B2 P21281 V-type proton ATPase subunit B, brain isoform chr8 Not Cancer Driver No 1 hippie, biogrid 63 49 4 4 1
ATP6V1E1 ATP6V1E1 P36543 V-type proton ATPase subunit E 1 chr22 Not Cancer Driver No 1 hippie, biogrid 27 27 3 3 2
BCKDHA BCKDHA P12694 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 53 121 18 18 11
BORCS6 BORCS6 Q96GS4 BLOC-1-related complex subunit 6 chr17 Not Cancer Driver No 1 hippie 17 269 11 11 0
C6orf203_ENST00000405204 MTRES1 Q9P0P8 Mitochondrial transcription rescue factor 1 chr6 Not Cancer Driver No 1 intact 28 45 4 4 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 hippie, biogrid 65 334 38 38 0
CHCHD4_ENST00000396914 CHCHD4 Q8N4Q1 Mitochondrial intermembrane space import and assembly protein 40 chr3 Not Cancer Driver No 1 hippie, biogrid 18 82 8 8 0
COQ10B COQ10B Q9H8M1 Coenzyme Q-binding protein COQ10 homolog B, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 21 10 1 1 0
COQ2_ENST00000647002 COQ2 Q96H96 4-hydroxybenzoate polyprenyltransferase, mitochondrial chr4 Not Cancer Driver No 1 hippie 23 25 0 0 17
COQ5 COQ5 Q5HYK3 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie 45 15 2 2 0
COQ8B COQ8B Q96D53 Atypical kinase COQ8B, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 53 117 15 15 8
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 hippie, biogrid 61 84 13 13 0
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 17 5 1 1 1
COX7A2L COX7A2L O14548 Cytochrome c oxidase subunit 7A-related protein, mitochondrial chr2 Not Cancer Driver No 2 hippie, biogrid 13 0 0 0 0
CRELD1_ENST00000383811 CRELD1 Q96HD1 Protein disulfide isomerase CRELD1 chr3 Not Cancer Driver No 1 hippie, biogrid 45 44 7 7 4
CYB5B CYB5B O43169 Cytochrome b5 type B chr16 Not Cancer Driver No 1 hippie, biogrid 17 58 2 2 0
CYC1 CYC1 P08574 Cytochrome c1, heme protein, mitochondrial chr8 Not Cancer Driver No 5 intact, hippie, biogrid 65 35 8 8 2
DCTN2_ENST00000548249 DCTN2 Q13561 Dynactin subunit 2 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 46 253 32 32 0
DCTN3 DCTN3 O75935 Dynactin subunit 3 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 18 3 0 0 0
DCTN4_ENST00000447998 DCTN4 Q9UJW0 Dynactin subunit 4 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 47 138 18 18 0
DCTN5 DCTN5 Q9BTE1 Dynactin subunit 5 chr16 Not Cancer Driver No 2 hippie, biogrid 23 0 0 0 0
DCTN6 DCTN6 O00399 Dynactin subunit 6 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 25 45 0 0 0
DOCK11 DOCK11 Q5JSL3 Dedicator of cytokinesis protein 11 chrX Not Cancer Driver No 2 hippie, biogrid 312 240 29 29 0
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 hippie, biogrid 109 100 14 14 0
EEF1B2_ENST00000236957 EEF1B2 P24534 Elongation factor 1-beta chr2 Not Cancer Driver No 1 hippie, biogrid 63 71 11 11 0
EEF2 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 111 78 14 14 1
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EMC2 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 hippie, biogrid 48 29 3 3 0
EMC4 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 1 hippie, biogrid 15 17 2 2 0
EMC8 EMC8 O43402 ER membrane protein complex subunit 8 chr16 Not Cancer Driver No 1 hippie, biogrid 15 20 0 0 0
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 1 hippie, biogrid 298 396 70 70 3
FAM131B_ENST00000409222 FAM131B Q86XD5 Protein FAM131B chr7 Census Yes 1 intact, hippie, biogrid 78 276 61 61 0
FAM189B FAM189B P81408 Protein FAM189B chr1 Not Cancer Driver No 1 intact, hippie 56 302 21 21 0
FMC1 FMC1 Q96HJ9 Protein FMC1 homolog chr7 Not Cancer Driver No 1 intact, hippie 9 30 1 1 0
FUCA2 FUCA2 Q9BTY2 Plasma alpha-L-fucosidase chr6 Not Cancer Driver No 1 intact, hippie, biogrid 50 2 0 0 0
GSDME_ENST00000409775 GSDME O60443 Gasdermin-E chr7 Not Cancer Driver No 1 hippie 81 14 3 3 0
HCST HCST Q9UBK5 Hematopoietic cell signal transducer chr19 Not Cancer Driver No 1 hippie, biogrid 6 12 0 0 0
HDAC10 HDAC10 Q969S8 Polyamine deacetylase HDAC10 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 67 121 11 11 0
HMOX2_ENST00000406590 HMOX2 P30519 Heme oxygenase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 27 74 10 10 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 336 666 69 69 2
ILF3_ENST00000590261 ILF3 Q12906 Interleukin enhancer-binding factor 3 chr19 Not Cancer Driver No 1 hippie, biogrid 103 674 82 82 0
INS INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 15 5 1 1 22
ITFG1 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 70 18 3 3 0
KLRC2 KLRC2 P26717 NKG2-C type II integral membrane protein chr12 Not Cancer Driver No 1 hippie, biogrid 55 45 17 17 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 99 175 15 15 10
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 131 18 2 2 1
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 287 749 159 159 3
MPV17 MPV17 P39210 Protein Mpv17 chr2 Not Cancer Driver No 1 hippie, biogrid 21 0 0 0 16
MYLK2 MYLK2 Q9H1R3 Myosin light chain kinase 2, skeletal/cardiac muscle chr20 Not Cancer Driver No 1 intact, hippie 118 277 64 64 2
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 Not Cancer Driver No 1 intact, hippie 22 44 4 4 0
NDFIP2_ENST00000218652 NDFIP2 Q9NV92 NEDD4 family-interacting protein 2 chr13 Not Cancer Driver No 1 intact, hippie 27 198 13 13 0
NDUFA12 NDUFA12 Q9UI09 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 chr12 Not Cancer Driver No 1 intact, hippie 18 31 6 6 0
NDUFA8 NDUFA8 P51970 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 chr9 Not Cancer Driver No 1 hippie, biogrid 25 33 1 1 2
NDUFS1_ENST00000449699 NDUFS1 P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 81 40 3 3 2
NDUFS3 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 34 26 3 3 2
NDUFS4 NDUFS4 O43181 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 26 92 17 17 1
NDUFS5_ENST00000372967 NDUFS5 O43920 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 15 31 3 3 0
NDUFS7 NDUFS7 O75251 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 36 30 3 3 1
NDUFS8 NDUFS8 O00217 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 27 37 2 2 3
NDUFV1 NDUFV1 P49821 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 66 57 9 9 3
NDUFV2 NDUFV2 P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 40 69 15 15 0
NENF NENF Q9UMX5 Neudesin chr1 Not Cancer Driver No 1 hippie, biogrid 15 98 7 7 0
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 230 881 150 150 0
NNT_ENST00000344920 NNT Q13423 NAD(P) transhydrogenase, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 129 47 6 6 11
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 intact, hippie 29 249 22 22 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 31 33 2 2 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 50 10 5 5 0
P4HA1_ENST00000394890 P4HA1 P13674 Prolyl 4-hydroxylase subunit alpha-1 chr10 Not Cancer Driver No 1 hippie, biogrid 65 54 8 8 0
PBXIP1 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 100 605 86 86 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PDHB PDHB P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 32 4 0 0 2
PEX19 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 41 266 38 38 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 31 26 4 4 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 Not Cancer Driver No 1 hippie, biogrid 62 93 4 4 9
PROC PROC P04070 Vitamin K-dependent protein C chr2 Not Cancer Driver No 1 intact, hippie, biogrid 73 41 9 9 36
PRRG1_ENST00000378628 PRRG1 O14668 Transmembrane gamma-carboxyglutamic acid protein 1 chrX Not Cancer Driver No 1 intact, hippie 43 88 21 21 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 intact, hippie 32 65 15 15 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 intact, hippie 66 2 1 1 6
RCN2_ENST00000394885 RCN2 Q14257 Reticulocalbin-2 chr15 Not Cancer Driver No 1 hippie, biogrid 35 125 11 11 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RNF24_ENST00000358395 RNF24 Q9Y225 RING finger protein 24 chr20 Not Cancer Driver No 1 intact, hippie 18 13 3 3 0
RPL4 RPL4 P36578 60S ribosomal protein L4 chr15 Not Cancer Driver No 1 hippie, biogrid 49 222 31 31 0
SCYL3_ENST00000367770 SCYL3 Q8IZE3 Protein-associating with the carboxyl-terminal domain of ezrin chr1 Not Cancer Driver No 1 hippie, biogrid 81 249 28 28 0
SDHAF4 SDHAF4 Q5VUM1 Succinate dehydrogenase assembly factor 4, mitochondrial chr6 Not Cancer Driver No 1 hippie 14 76 10 10 0
SERPINB1 SERPINB1 P30740 Leukocyte elastase inhibitor chr6 Not Cancer Driver No 1 intact, hippie, biogrid 39 14 0 0 0
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 intact, hippie 31 29 1 1 0
SHLD3 SHLD3 Q6ZNX1 Shieldin complex subunit 3 chr5 Not Cancer Driver No 1 intact 3 81 1 1 0
SIRT3 SIRT3 Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 33 60 2 2 0
SLC11A2_ENST00000262051 SLC11A2 P49281 Natural resistance-associated macrophage protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 60 38 5 5 3
SLC15A2 SLC15A2 Q16348 Solute carrier family 15 member 2 chr3 Not Cancer Driver No 1 hippie, biogrid 153 37 7 7 0
SLC2A9 SLC2A9 Q9NRM0 Solute carrier family 2, facilitated glucose transporter member 9 chr4 Not Cancer Driver No 1 hippie, biogrid 93 49 5 5 5
SLC39A4 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 77 116 11 11 9
SPPL2B SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 Not Cancer Driver No 1 hippie, biogrid 68 99 17 17 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
SSC5D SSC5D A1L4H1 Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D chr19 Not Cancer Driver No 1 hippie, biogrid 81 1194 70 70 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 24 25 4 4 0
TSPAN10_ENST00000611590 TSPAN10 Q9H1Z9 Tetraspanin-10 chr17 Not Cancer Driver No 1 hippie, biogrid 29 81 6 6 0
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 2 intact, hippie, biogrid 40 63 11 11 5
TUBGCP3 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 1 hippie, biogrid 109 156 16 16 0
UQCR10 UQCR10 Q9UDW1 Cytochrome b-c1 complex subunit 9 chr22 Not Cancer Driver No 1 hippie, biogrid 12 0 0 0 0
UQCRB_ENST00000287022 UQCRB P14927 Cytochrome b-c1 complex subunit 7 chr8 Not Cancer Driver No 3 hippie, biogrid 28 2 1 1 0
UQCRC1 UQCRC1 P31930 Cytochrome b-c1 complex subunit 1, mitochondrial chr3 Not Cancer Driver No 3 hippie, biogrid 57 55 6 6 2
UQCRC2 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 3 hippie, biogrid 53 48 13 13 1
UQCRFS1 UQCRFS1 P47985 Cytochrome b-c1 complex subunit Rieske, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 43 47 4 4 1
UQCRQ_ENST00000378665 UQCRQ O14949 Cytochrome b-c1 complex subunit 8 chr5 Not Cancer Driver No 2 hippie, biogrid 9 12 1 1 1
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie, biogrid 88 186 16 16 16