Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 112 | 43 | 5 | 5 | 5 |
| ACTC1 | ACTC1 | P68032 | Actin, alpha cardiac muscle 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 114 | 48 | 19 | 19 | 11 |
| ACTG1_ENST00000575087 | ACTG1 | P63261 | Actin, cytoplasmic 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 73 | 42 | 10 | 10 | 16 |
| ACTL6A | ACTL6A | O96019 | Actin-like protein 6A | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 61 | 74 | 15 | 15 | 0 |
| ACTN4 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | Not Cancer Driver | No | 1 | hippie | 131 | 244 | 42 | 42 | 8 |
| ACTR5 | ACTR5 | Q9H9F9 | Actin-related protein 5 | chr20 | Not Cancer Driver | No | 4 | hippie, biogrid | 63 | 163 | 23 | 23 | 0 |
| ACTR8 | ACTR8 | Q9H981 | Actin-related protein 8 | chr3 | Not Cancer Driver | No | 5 | hippie, biogrid | 61 | 239 | 21 | 21 | 0 |
| ADRM1 | ADRM1 | Q16186 | Proteasomal ubiquitin receptor ADRM1 | chr20 | Not Cancer Driver | No | 6 | hippie, biogrid | 49 | 296 | 40 | 40 | 0 |
| ANP32B | ANP32B | Q92688 | Acidic leucine-rich nuclear phosphoprotein 32 family member B | chr9 | Not Cancer Driver | No | 1 | hippie | 22 | 117 | 12 | 12 | 0 |
| ANP32E | ANP32E | Q9BTT0 | Acidic leucine-rich nuclear phosphoprotein 32 family member E | chr1 | Not Cancer Driver | No | 1 | hippie | 40 | 135 | 18 | 18 | 0 |
| ANXA1_ENST00000257497 | ANXA1 | P04083 | Annexin A1 | chr9 | Not Cancer Driver | No | 1 | hippie | 59 | 61 | 12 | 12 | 0 |
| ANXA4 | ANXA4 | P09525 | Annexin A4 | chr2 | Not Cancer Driver | No | 1 | hippie | 47 | 41 | 6 | 6 | 0 |
| ANXA7 | ANXA7 | P20073 | Annexin A7 | chr10 | Not Cancer Driver | No | 1 | hippie | 68 | 215 | 37 | 37 | 0 |
| ANXA8L1 | ANXA8L1 | Q5VT79 | Annexin A8-like protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 5 | 37 | 0 | 0 | 0 |
| APOA1_ENST00000375320 | APOA1 | P02647 | Apolipoprotein A-I | chr11 | Not Cancer Driver | No | 1 | hippie | 28 | 131 | 8 | 8 | 3 |
| APOB | APOB | P04114 | Apolipoprotein B-100 | chr2 | Not Cancer Driver | No | 1 | hippie | 1022 | 315 | 72 | 72 | 3 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 128 | 418 | 71 | 71 | 17 |
| AR | AR | P10275 | Androgen receptor | chrX | Census, Compendium | Yes | 1 | hippie, biogrid | 196 | 443 | 88 | 88 | 169 |
| ARG1_ENST00000368087 | ARG1 | P05089 | Arginase-1 | chr6 | Not Cancer Driver | No | 1 | hippie | 41 | 83 | 12 | 12 | 9 |
| ARMT1 | ARMT1 | Q9H993 | Damage-control phosphatase ARMT1 | chr6 | Not Cancer Driver | No | 1 | hippie | 53 | 1 | 0 | 0 | 0 |
| ARNTL | ARNTL | O00327 | Aryl hydrocarbon receptor nuclear translocator-like protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 71 | 332 | 40 | 40 | 0 |
| ASPRV1 | ASPRV1 | Q53RT3 | Retroviral-like aspartic protease 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 66 | 85 | 18 | 18 | 3 |
| BAG1 | BAG1 | Q99933 | BAG family molecular chaperone regulator 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 195 | 9 | 9 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
| BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
| BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
| CALM1 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | Not Cancer Driver | No | 1 | hippie | 19 | 115 | 15 | 15 | 7 |
| CAP1_ENST00000372805 | CAP1 | Q01518 | Adenylyl cyclase-associated protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 70 | 156 | 31 | 31 | 0 |
| CAPZA1 | CAPZA1 | P52907 | F-actin-capping protein subunit alpha-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 40 | 41 | 2 | 2 | 0 |
| CASP14 | CASP14 | P31944 | Caspase-14 | chr19 | Not Cancer Driver | No | 1 | hippie | 50 | 84 | 13 | 13 | 0 |
| CBX7 | CBX7 | O95931 | Chromobox protein homolog 7 | chr22 | Not Cancer Driver | No | 1 | hippie | 40 | 175 | 34 | 34 | 0 |
| CCDC144A | CCDC144A | A2RUR9 | Coiled-coil domain-containing protein 144A | chr17 | Not Cancer Driver | No | 1 | hippie | 182 | 973 | 135 | 135 | 0 |
| CCDC74A | CCDC74A | Q96AQ1 | Coiled-coil domain-containing protein 74A | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 351 | 84 | 84 | 0 |
| CCDC74B | CCDC74B | Q96LY2 | Coiled-coil domain-containing protein 74B | chr2 | Not Cancer Driver | No | 3 | hippie, biogrid | 74 | 339 | 63 | 63 | 0 |
| CCDC92 | CCDC92 | Q53HC0 | Coiled-coil domain-containing protein 92 | chr12 | Not Cancer Driver | No | 3 | hippie, biogrid | 60 | 299 | 49 | 49 | 0 |
| CCNDBP1 | CCNDBP1 | O95273 | Cyclin-D1-binding protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 63 | 5 | 5 | 0 |
| CDC5L | CDC5L | Q99459 | Cell division cycle 5-like protein | chr6 | Not Cancer Driver | No | 1 | hippie | 100 | 618 | 77 | 77 | 0 |
| CDSN | CDSN | Q15517 | Corneodesmosin | chr6 | Not Cancer Driver | No | 1 | hippie | 56 | 469 | 52 | 52 | 0 |
| CFL1_ENST00000308162 | CFL1 | P23528 | Cofilin-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 21 | 4 | 0 | 0 | 0 |
| CHMP4C | CHMP4C | Q96CF2 | Charged multivesicular body protein 4c | chr8 | Not Cancer Driver | No | 1 | hippie | 33 | 224 | 31 | 31 | 0 |
| CIAPIN1 | CIAPIN1 | Q6FI81 | Anamorsin | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 119 | 8 | 8 | 0 |
| CNOT3 | CNOT3 | O75175 | CCR4-NOT transcription complex subunit 3 | chr19 | Census, Compendium | Yes | 1 | hippie | 120 | 538 | 78 | 78 | 4 |
| COMMD4 | COMMD4 | Q9H0A8 | COMM domain-containing protein 4 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 9 | 1 | 1 | 0 |
| CSTA | CSTA | P01040 | Cystatin-A | chr3 | Not Cancer Driver | No | 1 | hippie | 16 | 54 | 9 | 9 | 0 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | Census, Compendium | Yes | 1 | hippie | 415 | 288 | 301 | 301 | 14 |
| CTSD | CTSD | P07339 | Cathepsin D | chr11 | Not Cancer Driver | No | 1 | hippie | 57 | 6 | 1 | 1 | 2 |
| CYB5A | CYB5A | P00167 | Cytochrome b5 | chr18 | Not Cancer Driver | No | 1 | hippie | 20 | 70 | 12 | 12 | 1 |
| CYB5B | CYB5B | O43169 | Cytochrome b5 type B | chr16 | Not Cancer Driver | No | 1 | hippie | 17 | 58 | 2 | 2 | 0 |
| DSC1 | DSC1 | Q08554 | Desmocollin-1 | chr18 | Not Cancer Driver | No | 1 | hippie | 219 | 265 | 65 | 65 | 0 |
| DSC3 | DSC3 | Q14574 | Desmocollin-3 | chr18 | Not Cancer Driver | No | 1 | hippie | 204 | 213 | 57 | 57 | 0 |
| DSP | DSP | P15924 | Desmoplakin | chr6 | Not Cancer Driver | No | 1 | hippie | 483 | 1124 | 204 | 204 | 6 |
| E2F1 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | Not Cancer Driver | No | 1 | hippie | 49 | 272 | 23 | 23 | 0 |
| E2F2 | E2F2 | Q14209 | Transcription factor E2F2 | chr1 | Not Cancer Driver | No | 1 | hippie | 42 | 282 | 28 | 28 | 0 |
| E2F3 | E2F3 | O00716 | Transcription factor E2F3 | chr6 | Not Cancer Driver | No | 1 | hippie | 46 | 253 | 20 | 20 | 0 |
| ECHS1 | ECHS1 | P30084 | Enoyl-CoA hydratase, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie | 51 | 7 | 1 | 1 | 14 |
| ECPAS_ENST00000338205 | ECPAS | Q5VYK3 | Proteasome adapter and scaffold protein ECM29 | chr9 | Not Cancer Driver | No | 1 | hippie | 176 | 240 | 22 | 22 | 0 |
| EEF1G | EEF1G | P26641 | Elongation factor 1-gamma | chr11 | Not Cancer Driver | No | 1 | hippie | 44 | 66 | 5 | 5 | 0 |
| EEF2 | EEF2 | P13639 | Elongation factor 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 111 | 78 | 14 | 14 | 1 |
| EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
| EIF1B | EIF1B | O60739 | Eukaryotic translation initiation factor 1b | chr3 | Not Cancer Driver | No | 1 | hippie | 12 | 6 | 0 | 0 | 0 |
| EIF4A1 | EIF4A1 | P60842 | Eukaryotic initiation factor 4A-I | chr17 | Not Cancer Driver | No | 1 | hippie | 48 | 35 | 7 | 7 | 0 |
| ELF4 | ELF4 | Q99607 | ETS-related transcription factor Elf-4 | chrX | Census, Compendium | Yes | 1 | hippie | 88 | 486 | 60 | 60 | 0 |
| ELK3 | ELK3 | P41970 | ETS domain-containing protein Elk-3 | chr12 | Not Cancer Driver | No | 1 | hippie | 58 | 163 | 16 | 16 | 0 |
| EPPK1 | EPPK1 | P58107 | Epiplakin | chr8 | Not Cancer Driver | No | 1 | hippie | 417 | 1336 | 67 | 67 | 0 |
| FBXO32 | FBXO32 | Q969P5 | F-box only protein 32 | chr8 | Not Cancer Driver | No | 1 | hippie | 54 | 0 | 0 | 0 | 0 |
| FDFT1_ENST00000615631 | FDFT1 | P37268 | Squalene synthase | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 19 | 0 | 0 | 0 |
| FHOD1 | FHOD1 | Q9Y613 | FH1/FH2 domain-containing protein 1 | chr16 | Not Cancer Driver | No | 3 | hippie, biogrid | 151 | 575 | 82 | 82 | 0 |
| FLG | FLG | P20930 | Filaggrin | chr1 | Not Cancer Driver | No | 1 | hippie | 1612 | 3956 | 1593 | 1593 | 0 |
| FTH1_ENST00000620041 | FTH1 | P02794 | Ferritin heavy chain | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 57 | 7 | 7 | 0 |
| FTL | FTL | P02792 | Ferritin light chain | chr19 | Not Cancer Driver | No | 1 | hippie | 19 | 36 | 7 | 7 | 2 |
| GSTM3_ENST00000361066 | GSTM3 | P21266 | Glutathione S-transferase Mu 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 32 | 0 | 0 | 0 | 0 |
| GTF2I | GTF2I | P78347 | General transcription factor II-I | chr7 | Compendium | Yes | 1 | hippie, biogrid | 74 | 365 | 27 | 27 | 0 |
| HAUS3 | HAUS3 | Q68CZ6 | HAUS augmin-like complex subunit 3 | chr4 | Not Cancer Driver | No | 1 | hippie | 61 | 55 | 7 | 7 | 0 |
| HAUS7 | HAUS7 | Q99871 | HAUS augmin-like complex subunit 7 | chrX | Not Cancer Driver | No | 1 | hippie | 51 | 78 | 7 | 7 | 0 |
| HBB | HBB | P68871 | Hemoglobin subunit beta | chr11 | Not Cancer Driver | No | 1 | hippie | 45 | 7 | 2 | 2 | 5 |
| HERC2 | HERC2 | O95714 | E3 ubiquitin-protein ligase HERC2 | chr15 | Compendium | Yes | 1 | hippie, biogrid | 718 | 971 | 150 | 150 | 1 |
| HGS | HGS | O14964 | Hepatocyte growth factor-regulated tyrosine kinase substrate | chr17 | Not Cancer Driver | No | 1 | hippie | 109 | 528 | 74 | 74 | 0 |
| HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | Not Cancer Driver | No | 1 | hippie | 73 | 282 | 35 | 35 | 0 |
| HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 10 | 118 | 8 | 8 | 20 |
| HUWE1_ENST00000262854 | HUWE1 | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | chrX | Not Cancer Driver | No | 1 | hippie | 669 | 2091 | 329 | 329 | 21 |
| IDE | IDE | P14735 | Insulin-degrading enzyme | chr10 | Not Cancer Driver | No | 1 | hippie | 90 | 96 | 8 | 8 | 0 |
| INO80B | INO80B | Q9C086 | INO80 complex subunit B | chr2 | Not Cancer Driver | No | 4 | hippie, biogrid | 35 | 336 | 33 | 33 | 0 |
| INO80C_ENST00000334598 | INO80C | Q6PI98 | INO80 complex subunit C | chr18 | Not Cancer Driver | No | 4 | hippie, biogrid | 18 | 109 | 11 | 11 | 0 |
| INO80D | INO80D | Q53TQ3 | INO80 complex subunit D | chr2 | Not Cancer Driver | No | 3 | hippie, biogrid | 110 | 738 | 93 | 93 | 0 |
| INO80E | INO80E | Q8NBZ0 | INO80 complex subunit E | chr16 | Not Cancer Driver | No | 5 | hippie, biogrid | 21 | 210 | 21 | 21 | 0 |
| INO80_ENST00000401393 | INO80 | Q9ULG1 | Chromatin-remodeling ATPase INO80 | chr15 | Compendium | Yes | 5 | hippie, biogrid | 173 | 682 | 76 | 76 | 0 |
| IVL | IVL | P07476 | Involucrin | chr1 | Not Cancer Driver | No | 1 | hippie | 115 | 585 | 115 | 115 | 0 |
| KCMF1 | KCMF1 | Q9P0J7 | E3 ubiquitin-protein ligase KCMF1 | chr2 | Not Cancer Driver | No | 1 | hippie | 48 | 270 | 36 | 36 | 0 |
| KDELR1 | KDELR1 | P24390 | ER lumen protein-retaining receptor 1 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 32 | 0 | 0 | 0 | 0 |
| KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | Not Cancer Driver | No | 1 | hippie | 67 | 291 | 28 | 28 | 3 |
| KRT1 | KRT1 | P04264 | Keratin, type II cytoskeletal 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 133 | 426 | 98 | 98 | 20 |
| KRT10 | KRT10 | P13645 | Keratin, type I cytoskeletal 10 | chr17 | Not Cancer Driver | No | 1 | hippie | 79 | 297 | 38 | 38 | 16 |
| KRT12 | KRT12 | Q99456 | Keratin, type I cytoskeletal 12 | chr17 | Not Cancer Driver | No | 1 | hippie | 76 | 218 | 34 | 34 | 18 |
| KRT19 | KRT19 | P08727 | Keratin, type I cytoskeletal 19 | chr17 | Not Cancer Driver | No | 1 | hippie | 57 | 165 | 19 | 19 | 0 |
| KRT26 | KRT26 | Q7Z3Y9 | Keratin, type I cytoskeletal 26 | chr17 | Not Cancer Driver | No | 1 | hippie | 75 | 146 | 20 | 20 | 0 |
| KRT28 | KRT28 | Q7Z3Y7 | Keratin, type I cytoskeletal 28 | chr17 | Not Cancer Driver | No | 1 | hippie | 107 | 157 | 30 | 30 | 0 |
| KRT6B | KRT6B | P04259 | Keratin, type II cytoskeletal 6B | chr12 | Not Cancer Driver | No | 1 | hippie | 121 | 162 | 39 | 39 | 1 |
| KRT73 | KRT73 | Q86Y46 | Keratin, type II cytoskeletal 73 | chr12 | Not Cancer Driver | No | 1 | hippie | 121 | 60 | 14 | 14 | 0 |
| KRT78 | KRT78 | Q8N1N4 | Keratin, type II cytoskeletal 78 | chr12 | Not Cancer Driver | No | 1 | hippie | 96 | 122 | 27 | 27 | 0 |
| KRT80 | KRT80 | Q6KB66 | Keratin, type II cytoskeletal 80 | chr12 | Not Cancer Driver | No | 1 | hippie | 54 | 147 | 20 | 20 | 0 |
| KRT9 | KRT9 | P35527 | Keratin, type I cytoskeletal 9 | chr17 | Not Cancer Driver | No | 1 | hippie | 104 | 427 | 68 | 68 | 21 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
| LMNA | LMNA | P02545 | Prelamin-A/C | chr1 | Census | Yes | 1 | hippie | 68 | 544 | 49 | 49 | 131 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact | 519 | 90 | 17 | 17 | 23 |
| MAP3K1 | MAP3K1 | Q13233 | Mitogen-activated protein kinase kinase kinase 1 | chr5 | Census, Compendium | Yes | 1 | hippie | 184 | 820 | 62 | 62 | 3 |
| MAPK6 | MAPK6 | Q16659 | Mitogen-activated protein kinase 6 | chr15 | Not Cancer Driver | No | 1 | hippie | 79 | 165 | 20 | 20 | 0 |
| MCRS1_ENST00000550165 | MCRS1 | Q96EZ8 | Microspherule protein 1 | chr12 | Not Cancer Driver | No | 5 | hippie, biogrid | 72 | 151 | 18 | 18 | 0 |
| NACA_ENST00000356769 | NACA | Q13765 | Nascent polypeptide-associated complex subunit alpha | chr12 | Census | Yes | 1 | hippie | 37 | 143 | 26 | 26 | 0 |
| NCAPD3 | NCAPD3 | P42695 | Condensin-2 complex subunit D3 | chr11 | Not Cancer Driver | No | 1 | hippie | 193 | 304 | 42 | 42 | 1 |
| NFRKB_ENST00000446488 | NFRKB | Q6P4R8 | Nuclear factor related to kappa-B-binding protein | chr11 | Not Cancer Driver | No | 5 | hippie, biogrid | 128 | 838 | 74 | 74 | 0 |
| NOS2 | NOS2 | P35228 | Nitric oxide synthase, inducible | chr17 | Not Cancer Driver | No | 1 | hippie | 207 | 201 | 33 | 33 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
| OGT | OGT | O15294 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | chrX | Not Cancer Driver | No | 1 | hippie | 156 | 89 | 16 | 16 | 2 |
| PAAF1 | PAAF1 | Q9BRP4 | Proteasomal ATPase-associated factor 1 | chr11 | Not Cancer Driver | No | 4 | hippie, biogrid | 47 | 23 | 3 | 3 | 0 |
| PFN1 | PFN1 | P07737 | Profilin-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 16 | 7 | 1 | 1 | 3 |
| PJA1 | PJA1 | Q8NG27 | E3 ubiquitin-protein ligase Praja-1 | chrX | Not Cancer Driver | No | 1 | hippie | 112 | 525 | 94 | 94 | 0 |
| PKM_ENST00000335181 | PKM | P14618 | Pyruvate kinase PKM | chr15 | Not Cancer Driver | No | 1 | hippie | 78 | 58 | 13 | 13 | 0 |
| PKP1 | PKP1 | Q13835 | Plakophilin-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 106 | 190 | 26 | 26 | 0 |
| PLA2G2A_ENST00000375111 | PLA2G2A | P14555 | Phospholipase A2, membrane associated | chr1 | Not Cancer Driver | No | 1 | hippie | 25 | 0 | 0 | 0 | 0 |
| PLCG1_ENST00000373271 | PLCG1 | P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | chr20 | Census, Compendium | Yes | 1 | hippie, biogrid | 158 | 186 | 21 | 21 | 0 |
| PLRG1 | PLRG1 | O43660 | Pleiotropic regulator 1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 204 | 25 | 25 | 0 |
| PNP | PNP | P00491 | Purine nucleoside phosphorylase | chr14 | Not Cancer Driver | No | 1 | hippie | 38 | 29 | 2 | 2 | 5 |
| POF1B_ENST00000262753 | POF1B | Q8WVV4 | Protein POF1B | chrX | Not Cancer Driver | No | 1 | hippie | 154 | 391 | 104 | 104 | 1 |
| POTEE | POTEE | Q6S8J3 | POTE ankyrin domain family member E | chr2 | Not Cancer Driver | No | 1 | hippie | 305 | 462 | 92 | 92 | 0 |
| POTEF | POTEF | A5A3E0 | POTE ankyrin domain family member F | chr2 | Not Cancer Driver | No | 1 | hippie | 269 | 453 | 93 | 93 | 0 |
| PRDX1_ENST00000319248 | PRDX1 | Q06830 | Peroxiredoxin-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 22 | 40 | 5 | 5 | 0 |
| PRDX2 | PRDX2 | P32119 | Peroxiredoxin-2 | chr19 | Not Cancer Driver | No | 1 | hippie | 24 | 30 | 4 | 4 | 0 |
| PRDX3 | PRDX3 | P30048 | Thioredoxin-dependent peroxide reductase, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie | 23 | 23 | 3 | 3 | 0 |
| PRDX6 | PRDX6 | P30041 | Peroxiredoxin-6 | chr1 | Not Cancer Driver | No | 1 | hippie | 46 | 13 | 4 | 4 | 0 |
| PRPF19 | PRPF19 | Q9UMS4 | Pre-mRNA-processing factor 19 | chr11 | Not Cancer Driver | No | 1 | hippie | 71 | 109 | 16 | 16 | 0 |
| PSMA1_ENST00000396394 | PSMA1 | P25786 | Proteasome subunit alpha type-1 | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 48 | 51 | 9 | 9 | 0 |
| PSMA2 | PSMA2 | P25787 | Proteasome subunit alpha type-2 | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 20 | 0 | 0 | 0 | 0 |
| PSMA3 | PSMA3 | P25788 | Proteasome subunit alpha type-3 | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 27 | 30 | 5 | 5 | 0 |
| PSMA4_ENST00000559082 | PSMA4 | P25789 | Proteasome subunit alpha type-4 | chr15 | Not Cancer Driver | No | 2 | hippie, biogrid | 29 | 28 | 9 | 9 | 0 |
| PSMA5 | PSMA5 | P28066 | Proteasome subunit alpha type-5 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 24 | 23 | 1 | 1 | 0 |
| PSMA6 | PSMA6 | P60900 | Proteasome subunit alpha type-6 | chr14 | Not Cancer Driver | No | 1 | hippie | 37 | 2 | 1 | 1 | 0 |
| PSMA7 | PSMA7 | O14818 | Proteasome subunit alpha type-7 | chr20 | Not Cancer Driver | No | 2 | hippie, biogrid | 24 | 23 | 1 | 1 | 0 |
| PSMB1 | PSMB1 | P20618 | Proteasome subunit beta type-1 | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 25 | 14 | 2 | 2 | 0 |
| PSMB2 | PSMB2 | P49721 | Proteasome subunit beta type-2 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 24 | 0 | 0 | 0 | 0 |
| PSMB4 | PSMB4 | P28070 | Proteasome subunit beta type-4 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 23 | 18 | 2 | 2 | 0 |
| PSMB5 | PSMB5 | P28074 | Proteasome subunit beta type-5 | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 39 | 9 | 0 | 0 | 0 |
| PSMB6 | PSMB6 | P28072 | Proteasome subunit beta type-6 | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 19 | 22 | 1 | 1 | 0 |
| PSMB7 | PSMB7 | Q99436 | Proteasome subunit beta type-7 | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 25 | 26 | 3 | 3 | 0 |
| PSMB8 | PSMB8 | P28062 | Proteasome subunit beta type-8 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 62 | 7 | 7 | 3 |
| PSMB9 | PSMB9 | P28065 | Proteasome subunit beta type-9 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 17 | 1 | 1 | 1 |
| PSMC1 | PSMC1 | P62191 | 26S proteasome regulatory subunit 4 | chr14 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 36 | 165 | 10 | 10 | 0 |
| PSMC2_ENST00000292644 | PSMC2 | P35998 | 26S proteasome regulatory subunit 7 | chr7 | Not Cancer Driver | No | 5 | hippie, biogrid | 63 | 120 | 13 | 13 | 0 |
| PSMC3_ENST00000298852 | PSMC3 | P17980 | 26S proteasome regulatory subunit 6A | chr11 | Not Cancer Driver | No | 4 | hippie, biogrid | 55 | 131 | 10 | 10 | 0 |
| PSMC4 | PSMC4 | P43686 | 26S proteasome regulatory subunit 6B | chr19 | Not Cancer Driver | No | 4 | hippie, biogrid | 51 | 21 | 3 | 3 | 0 |
| PSMC5 | PSMC5 | P62195 | 26S proteasome regulatory subunit 8 | chr17 | Not Cancer Driver | No | 4 | hippie, biogrid | 52 | 64 | 6 | 6 | 0 |
| PSMC6_ENST00000606149 | PSMC6 | P62333 | 26S proteasome regulatory subunit 10B | chr14 | Not Cancer Driver | No | 4 | hippie, biogrid | 49 | 69 | 8 | 8 | 0 |
| PSMD1 | PSMD1 | Q99460 | 26S proteasome non-ATPase regulatory subunit 1 | chr2 | Not Cancer Driver | No | 5 | hippie, biogrid | 110 | 201 | 19 | 19 | 0 |
| PSMD10 | PSMD10 | O75832 | 26S proteasome non-ATPase regulatory subunit 10 | chrX | Not Cancer Driver | No | 4 | hippie, biogrid | 20 | 53 | 5 | 5 | 0 |
| PSMD11_ENST00000457654 | PSMD11 | O00231 | 26S proteasome non-ATPase regulatory subunit 11 | chr17 | Not Cancer Driver | No | 4 | hippie, biogrid | 51 | 0 | 0 | 0 | 0 |
| PSMD12 | PSMD12 | O00232 | 26S proteasome non-ATPase regulatory subunit 12 | chr17 | Not Cancer Driver | No | 4 | hippie, biogrid | 48 | 24 | 3 | 3 | 0 |
| PSMD13_ENST00000532097 | PSMD13 | Q9UNM6 | 26S proteasome non-ATPase regulatory subunit 13 | chr11 | Not Cancer Driver | No | 4 | hippie, biogrid | 30 | 13 | 3 | 3 | 0 |
| PSMD14 | PSMD14 | O00487 | 26S proteasome non-ATPase regulatory subunit 14 | chr2 | Not Cancer Driver | No | 4 | hippie, biogrid | 23 | 67 | 6 | 6 | 0 |
| PSMD2 | PSMD2 | Q13200 | 26S proteasome non-ATPase regulatory subunit 2 | chr3 | Not Cancer Driver | No | 5 | hippie, biogrid | 100 | 135 | 14 | 14 | 0 |
| PSMD3 | PSMD3 | O43242 | 26S proteasome non-ATPase regulatory subunit 3 | chr17 | Not Cancer Driver | No | 4 | hippie, biogrid | 69 | 152 | 19 | 19 | 0 |
| PSMD4_ENST00000368884 | PSMD4 | P55036 | 26S proteasome non-ATPase regulatory subunit 4 | chr1 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 43 | 243 | 25 | 25 | 0 |
| PSMD5 | PSMD5 | Q16401 | 26S proteasome non-ATPase regulatory subunit 5 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 2 | 1 | 1 | 0 |
| PSMD6_ENST00000295901 | PSMD6 | Q15008 | 26S proteasome non-ATPase regulatory subunit 6 | chr3 | Not Cancer Driver | No | 4 | hippie, biogrid | 33 | 40 | 3 | 3 | 0 |
| PSMD7 | PSMD7 | P51665 | 26S proteasome non-ATPase regulatory subunit 7 | chr16 | Not Cancer Driver | No | 4 | hippie, biogrid | 39 | 70 | 4 | 4 | 0 |
| PSMD8 | PSMD8 | P48556 | 26S proteasome non-ATPase regulatory subunit 8 | chr19 | Not Cancer Driver | No | 4 | hippie, biogrid | 20 | 78 | 2 | 2 | 0 |
| PTPN2 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 120 | 14 | 14 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 1 | hippie | 27 | 11 | 0 | 0 | 4 |
| RAD23A | RAD23A | P54725 | UV excision repair protein RAD23 homolog A | chr19 | Not Cancer Driver | No | 1 | hippie | 50 | 283 | 41 | 41 | 0 |
| RAD23B | RAD23B | P54727 | UV excision repair protein RAD23 homolog B | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 324 | 41 | 41 | 0 |
| RBCK1 | RBCK1 | Q9BYM8 | RanBP-type and C3HC4-type zinc finger-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 52 | 140 | 14 | 14 | 2 |
| RBP1_ENST00000619087 | RBP1 | P09455 | Retinol-binding protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 0 | 0 | 0 | 0 |
| RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
| RFFL_ENST00000394597 | RFFL | Q8WZ73 | E3 ubiquitin-protein ligase rififylin | chr17 | Not Cancer Driver | No | 1 | hippie | 50 | 150 | 21 | 21 | 0 |
| RGPD5_ENST00000393283 | RGPD5 | Q99666-2 | Isoform 2 of RANBP2-like and GRIP domain-containing protein 5/6 | chr2 | Not Cancer Driver | No | 3 | biogrid | 1 | 141 | 1 | 1 | 0 |
| RGPD8 | RGPD8 | O14715 | RANBP2-like and GRIP domain-containing protein 8 | chr2 | Not Cancer Driver | No | 3 | hippie, biogrid | 129 | 621 | 71 | 71 | 0 |
| RIPK4_ENST00000352483 | RIPK4 | P57078 | Receptor-interacting serine/threonine-protein kinase 4 | chr21 | Not Cancer Driver | No | 1 | hippie | 119 | 232 | 34 | 34 | 3 |
| RNF20 | RNF20 | Q5VTR2 | E3 ubiquitin-protein ligase BRE1A | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 126 | 561 | 64 | 64 | 0 |
| RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
| RPS21 | RPS21 | P63220 | 40S ribosomal protein S21 | chr20 | Not Cancer Driver | No | 1 | hippie | 8 | 0 | 0 | 0 | 0 |
| RUVBL1 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | Not Cancer Driver | No | 3 | hippie, biogrid | 54 | 67 | 7 | 7 | 0 |
| RUVBL2 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | Not Cancer Driver | No | 3 | hippie, biogrid | 62 | 100 | 13 | 13 | 0 |
| S100A14_ENST00000368701 | S100A14 | Q9HCY8 | Protein S100-A14 | chr1 | Not Cancer Driver | No | 1 | hippie | 15 | 55 | 9 | 9 | 0 |
| S100A16_ENST00000368703 | S100A16 | Q96FQ6 | Protein S100-A16 | chr1 | Not Cancer Driver | No | 1 | hippie | 17 | 21 | 1 | 1 | 0 |
| S100A7_ENST00000368722 | S100A7 | P31151 | Protein S100-A7 | chr1 | Census | Yes | 1 | hippie | 39 | 28 | 14 | 14 | 0 |
| SEM1_ENST00000356686 | SEM1 | Q6ZVN7 | Putative protein SEM1, isoform 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 2 | 52 | 1 | 1 | 0 |
| SERPINB12_ENST00000269491 | SERPINB12 | Q96P63 | Serpin B12 | chr18 | Not Cancer Driver | No | 1 | hippie | 82 | 21 | 6 | 6 | 0 |
| SERPINB3 | SERPINB3 | P29508 | Serpin B3 | chr18 | Not Cancer Driver | No | 1 | hippie | 142 | 47 | 28 | 28 | 0 |
| SERPINB5 | SERPINB5 | P36952 | Serpin B5 | chr18 | Not Cancer Driver | No | 1 | hippie | 57 | 50 | 7 | 7 | 0 |
| SET | SET | Q01105 | Protein SET | chr9 | Census, Compendium | Yes | 1 | hippie | 35 | 221 | 26 | 26 | 2 |
| SLC17A2_ENST00000265425 | SLC17A2 | O00624 | Sodium-dependent phosphate transport protein 3 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 12 | 5 | 5 | 0 |
| SMAD2_ENST00000402690 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | Census, Compendium | Yes | 1 | hippie | 79 | 137 | 12 | 12 | 0 |
| SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | Census, Compendium | Yes | 1 | hippie | 97 | 111 | 19 | 19 | 5 |
| SMAD7 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | Not Cancer Driver | No | 1 | hippie | 40 | 139 | 0 | 0 | 0 |
| SNRPA1 | SNRPA1 | P09661 | U2 small nuclear ribonucleoprotein A' | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 93 | 14 | 14 | 0 |
| SNW1_ENST00000261531 | SNW1 | Q13573 | SNW domain-containing protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 62 | 488 | 56 | 56 | 0 |
| SQSTM1 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | Not Cancer Driver | No | 1 | hippie | 54 | 267 | 32 | 32 | 30 |
| SRXN1 | SRXN1 | Q9BYN0 | Sulfiredoxin-1 | chr20 | Not Cancer Driver | No | 1 | hippie | 15 | 48 | 2 | 2 | 0 |
| SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
| TCF7_ENST00000518915 | TCF7 | P36402-2 | Isoform 4S of Transcription factor 7 | chr5 | Not Cancer Driver | No | 1 | hippie | 37 | 206 | 30 | 30 | 0 |
| TFPT | TFPT | P0C1Z6 | TCF3 fusion partner | chr19 | Census | Yes | 5 | hippie, biogrid | 41 | 237 | 41 | 41 | 0 |
| TGM3 | TGM3 | Q08188 | Protein-glutamine gamma-glutamyltransferase E | chr20 | Not Cancer Driver | No | 1 | hippie | 141 | 85 | 19 | 19 | 0 |
| TIPRL | TIPRL | O75663 | TIP41-like protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 25 | 3 | 3 | 0 |
| TMEM31 | TMEM31 | Q5JXX7 | Transmembrane protein 31 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 61 | 10 | 10 | 0 |
| TPI1_ENST00000396705 | TPI1 | P60174 | Triosephosphate isomerase | chr12 | Not Cancer Driver | No | 1 | hippie | 40 | 15 | 2 | 2 | 7 |
| TPT1_ENST00000530705 | TPT1 | P13693 | Translationally-controlled tumor protein | chr13 | Not Cancer Driver | No | 1 | hippie | 17 | 43 | 6 | 6 | 0 |
| TRIM27 | TRIM27 | P14373 | Zinc finger protein RFP | chr6 | Census | Yes | 1 | hippie | 59 | 87 | 11 | 11 | 0 |
| TRIM46 | TRIM46 | Q7Z4K8 | Tripartite motif-containing protein 46 | chr1 | Not Cancer Driver | No | 1 | hippie | 115 | 173 | 30 | 30 | 0 |
| TRIM54_ENST00000380075 | TRIM54 | Q9BYV2 | Tripartite motif-containing protein 54 | chr2 | Not Cancer Driver | No | 1 | hippie | 63 | 98 | 17 | 17 | 0 |
| TRIM55 | TRIM55 | Q9BYV6 | Tripartite motif-containing protein 55 | chr8 | Not Cancer Driver | No | 1 | hippie | 134 | 276 | 78 | 78 | 0 |
| TRIM63 | TRIM63 | Q969Q1 | E3 ubiquitin-protein ligase TRIM63 | chr1 | Not Cancer Driver | No | 1 | hippie | 47 | 71 | 13 | 13 | 0 |
| TUBA4A | TUBA4A | P68366 | Tubulin alpha-4A chain | chr2 | Not Cancer Driver | No | 1 | hippie | 73 | 39 | 4 | 4 | 5 |
| TXN | TXN | P10599 | Thioredoxin | chr9 | Not Cancer Driver | No | 1 | hippie | 6 | 0 | 0 | 0 | 0 |
| TXN2_ENST00000403313 | TXN2 | Q99757 | Thioredoxin, mitochondrial | chr22 | Not Cancer Driver | No | 1 | hippie | 22 | 34 | 4 | 4 | 0 |
| TXNL1_ENST00000590954 | TXNL1 | O43396 | Thioredoxin-like protein 1 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 89 | 4 | 4 | 0 |
| UBE2M | UBE2M | P61081 | NEDD8-conjugating enzyme Ubc12 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 32 | 6 | 6 | 0 |
| UBE3A | UBE3A | Q05086 | Ubiquitin-protein ligase E3A | chr15 | Not Cancer Driver | No | 3 | hippie, biogrid | 141 | 136 | 22 | 22 | 0 |
| UBLCP1 | UBLCP1 | Q8WVY7 | Ubiquitin-like domain-containing CTD phosphatase 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 39 | 42 | 4 | 4 | 0 |
| UCHL5 | UCHL5 | Q9Y5K5 | Ubiquitin carboxyl-terminal hydrolase isozyme L5 | chr1 | Not Cancer Driver | No | 1 | hippie | 33 | 41 | 7 | 7 | 0 |
| UNC45A | UNC45A | Q9H3U1 | Protein unc-45 homolog A | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 128 | 4 | 4 | 0 |
| USP12 | USP12 | O75317 | Ubiquitin carboxyl-terminal hydrolase 12 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 33 | 5 | 5 | 0 |
| USP14 | USP14 | P54578 | Ubiquitin carboxyl-terminal hydrolase 14 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 86 | 6 | 6 | 0 |
| USP28 | USP28 | Q96RU2 | Ubiquitin carboxyl-terminal hydrolase 28 | chr11 | Not Cancer Driver | No | 1 | hippie | 151 | 311 | 25 | 25 | 0 |
| WDR61 | WDR61 | Q9GZS3 | WD repeat-containing protein 61 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 7 | 1 | 1 | 0 |
| XPNPEP1 | XPNPEP1 | Q9NQW7-3 | Isoform 3 of Xaa-Pro aminopeptidase 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 98 | 6 | 6 | 0 |
| XPO5 | XPO5 | Q9HAV4 | Exportin-5 | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 112 | 64 | 7 | 7 | 0 |
| YWHAE | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | Census | Yes | 1 | hippie | 32 | 41 | 3 | 3 | 0 |
| YWHAZ_ENST00000395956 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 1 | hippie | 30 | 81 | 10 | 10 | 0 |
| YY1 | YY1 | P25490 | Transcriptional repressor protein YY1 | chr14 | Not Cancer Driver | No | 5 | hippie, biogrid | 37 | 336 | 26 | 26 | 2 |
| ZBED1 | ZBED1 | O96006 | E3 SUMO-protein ligase ZBED1 | chrX | Not Cancer Driver | No | 1 | hippie | 137 | 97 | 12 | 12 | 0 |
| ZFAND2B_ENST00000409336 | ZFAND2B | Q8WV99 | AN1-type zinc finger protein 2B | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 147 | 15 | 15 | 0 |
| ZRANB1 | ZRANB1 | Q9UGI0 | Ubiquitin thioesterase ZRANB1 | chr10 | Not Cancer Driver | No | 1 | hippie | 87 | 158 | 25 | 25 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|