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UBR4 ,UBR4 ,Q5T4S7
  • Uniprot Accession= Q5T4S7
  • Ensembl Transcript= ENST00000375254.7
  • Uniprot Name= UBR4
  • Name= E3 ubiquitin-protein ligase UBR4
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 63
  • Number of Interaction partner in biogrid: 110
  • Number of Interaction partner in hippie: 234
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
A1BG A1BG P04217 Alpha-1B-glycoprotein chr19 Not Cancer Driver No 2 intact, hippie, biogrid 57 155 20 20 0
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie, biogrid 56 28 6 6 0
ABHD10 ABHD10 Q9NUJ1 Palmitoyl-protein thioesterase ABHD10, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 38 7 2 2 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX Not Cancer Driver No 1 hippie, biogrid 104 68 5 5 0
ACLY_ENST00000590151 ACLY P53396 ATP-citrate synthase chr17 Not Cancer Driver No 1 hippie 120 114 12 12 0
ACSM5 ACSM5 Q6NUN0 Acyl-coenzyme A synthetase ACSM5, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 152 84 27 27 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 Not Cancer Driver No 1 hippie 130 40 8 8 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 1 hippie 126 141 15 15 11
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
AGTR1_ENST00000349243 AGTR1 P30556 Type-1 angiotensin II receptor chr3 Not Cancer Driver No 1 intact, hippie 95 0 0 0 1
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
AMOT AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 1 hippie, biogrid 161 909 128 128 0
ANPEP ANPEP P15144 Aminopeptidase N chr15 Not Cancer Driver No 1 hippie, biogrid 175 109 26 26 0
APOO APOO Q9BUR5 MICOS complex subunit MIC26 chrX Not Cancer Driver No 1 hippie, biogrid 25 23 4 4 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 157 80 11 11 1
AURKAIP1_ENST00000321751 AURKAIP1 Q9NWT8 Aurora kinase A-interacting protein chr1 Not Cancer Driver No 1 hippie 18 104 8 8 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 2 hippie, biogrid 51 63 8 8 0
BCR BCR P11274 Breakpoint cluster region protein chr22 Census, Compendium Yes 1 hippie, biogrid 146 603 69 69 0
BET1 BET1 O15155 BET1 homolog chr7 Not Cancer Driver No 1 hippie 14 7 2 2 0
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 Not Cancer Driver No 1 hippie 69 83 9 9 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
C1orf115 C1orf115 Q9H7X2 Uncharacterized protein C1orf115 chr1 Not Cancer Driver No 1 hippie, biogrid 9 93 1 1 0
C1orf87 C1orf87 Q8N0U7 Uncharacterized protein C1orf87 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 99 296 45 45 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 19 115 15 15 7
CAPN10 CAPN10 Q9HC96 Calpain-10 chr2 Not Cancer Driver No 1 hippie, biogrid 87 52 6 6 0
CCNG1_ENST00000393929 CCNG1 P51959 Cyclin-G1 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 25 0 0 0 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 Census Yes 1 hippie 31 185 20 20 0
CD96 CD96 P40200 T-cell surface protein tactile chr3 Not Cancer Driver No 1 hippie, biogrid 132 165 34 34 1
CDCA5 CDCA5 Q96FF9 Sororin chr11 Not Cancer Driver No 1 hippie 32 211 26 26 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 hippie 48 121 30 30 0
CEP250 CEP250 Q9BV73 Centrosome-associated protein CEP250 chr20 Not Cancer Driver No 1 hippie 250 1859 195 195 0
CEP57 CEP57 Q86XR8 Centrosomal protein of 57 kDa chr11 Not Cancer Driver No 1 hippie 61 403 50 50 0
CFC1 CFC1 P0CG37 Cryptic protein chr2 Not Cancer Driver No 2 hippie, biogrid 25 68 23 23 1
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 3 intact, hippie 287 145 18 18 151
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 Census, Compendium Yes 1 intact, hippie 335 157 130 130 13
CHIA_ENST00000343320 CHIA Q9BZP6 Acidic mammalian chitinase chr1 Not Cancer Driver No 3 intact, hippie, biogrid 116 42 10 10 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 Not Cancer Driver No 1 hippie, biogrid 59 17 3 3 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 Not Cancer Driver No 1 hippie, biogrid 56 5 2 2 0
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 17 5 1 1 1
CPNE5 CPNE5 Q9HCH3 Copine-5 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 78 83 8 8 0
CRYL1 CRYL1 Q9Y2S2 Lambda-crystallin homolog chr13 Not Cancer Driver No 1 intact, hippie, biogrid 36 29 3 3 0
CSAG1 CSAG1 Q6PB30 Putative chondrosarcoma-associated gene 1 protein chrX Not Cancer Driver No 1 intact, hippie 32 70 28 28 0
CSHL1 CSHL1 Q14406 Chorionic somatomammotropin hormone-like 1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 63 18 5 5 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 Not Cancer Driver No 1 intact, hippie, biogrid 59 132 16 16 2
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 Not Cancer Driver No 1 hippie 62 133 18 18 0
CST9 CST9 Q5W186 Cystatin-9 chr20 Not Cancer Driver No 2 hippie, biogrid 24 12 2 2 0
CTSB CTSB P07858 Cathepsin B chr8 Not Cancer Driver No 1 hippie, biogrid 41 7 2 2 0
CTSL CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie, biogrid 47 34 4 4 0
CTSS CTSS P25774 Cathepsin S chr1 Not Cancer Driver No 1 hippie, biogrid 54 0 0 0 0
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX46_ENST00000354283 DDX46 Q7L014 Probable ATP-dependent RNA helicase DDX46 chr5 Not Cancer Driver No 1 hippie, biogrid 120 510 72 72 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DEFB125 DEFB125 Q8N687 Beta-defensin 125 chr20 Not Cancer Driver No 1 hippie, biogrid 34 53 9 9 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DPF3_ENST00000556509 DPF3 Q92784 Zinc finger protein DPF3 chr14 Not Cancer Driver No 1 hippie 68 172 45 45 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 151 8 1 1 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 Not Cancer Driver No 1 hippie 34 15 5 5 0
DUSP2 DUSP2 Q05923 Dual specificity protein phosphatase 2 chr2 Not Cancer Driver No 1 hippie 24 23 3 3 0
ECPAS_ENST00000338205 ECPAS Q5VYK3 Proteasome adapter and scaffold protein ECM29 chr9 Not Cancer Driver No 1 hippie 176 240 22 22 0
EDA EDA Q92838 Ectodysplasin-A chrX Not Cancer Driver No 2 intact, hippie, biogrid 73 243 43 43 71
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie, biogrid 132 179 30 30 3
EGFL7_ENST00000308874 EGFL7 Q9UHF1 Epidermal growth factor-like protein 7 chr9 Not Cancer Driver No 1 hippie, biogrid 24 36 2 2 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF5B EIF5B O60841 Eukaryotic translation initiation factor 5B chr2 Not Cancer Driver No 1 hippie, biogrid 122 718 71 71 0
ELFN2_ENST00000613079 ELFN2 Q5R3F8 Protein phosphatase 1 regulatory subunit 29 chr22 Not Cancer Driver No 1 hippie, biogrid 146 300 46 46 0
ELMO3 ELMO3 Q96BJ8-3 Isoform 3 of Engulfment and cell motility protein 3 chr16 Not Cancer Driver No 1 hippie, biogrid 77 175 20 20 0
ELP2_ENST00000358232 ELP2 Q6IA86 Elongator complex protein 2 chr18 Not Cancer Driver No 1 hippie, biogrid 65 16 2 2 0
EMID1 EMID1 Q96A84 EMI domain-containing protein 1 chr22 Not Cancer Driver No 2 hippie, biogrid 47 311 38 38 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 Not Cancer Driver No 1 hippie, biogrid 125 669 69 69 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 Census, Compendium Yes 1 intact 280 71 15 15 0
ERG_ENST00000288319 ERG P11308 Transcriptional regulator ERG chr21 Census, Compendium Yes 1 hippie 95 296 54 54 0
ERMAP_ENST00000372514 ERMAP Q96PL5 Erythroid membrane-associated protein chr1 Not Cancer Driver No 1 intact, hippie, biogrid 55 48 5 5 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 intact, hippie 83 241 34 34 0
FAF2 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 hippie 54 171 16 16 0
FBXW5 FBXW5 Q969U6 F-box/WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 64 74 10 10 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 Census, Compendium Yes 1 intact 238 228 44 44 72
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 intact 113 162 28 28 0
FLNB_ENST00000295956 FLNB O75369 Filamin-B chr3 Not Cancer Driver No 1 hippie 362 1183 170 170 19
FOXK1 FOXK1 P85037 Forkhead box protein K1 chr7 Not Cancer Driver No 1 intact, hippie 97 511 65 65 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 Not Cancer Driver No 1 hippie 79 548 64 64 0
FSTL4 FSTL4 Q6MZW2 Follistatin-related protein 4 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 134 96 12 12 0
FURIN_ENST00000610579 FURIN P09958 Furin chr15 Not Cancer Driver No 1 hippie, biogrid 93 283 35 35 0
FUZ FUZ Q9BT04 Protein fuzzy homolog chr19 Not Cancer Driver No 1 intact, hippie, biogrid 38 43 4 4 0
GML GML Q99445 Glycosyl-phosphatidylinositol-anchored molecule-like protein chr8 Not Cancer Driver No 1 intact, hippie, biogrid 49 12 6 6 0
GOLGA1 GOLGA1 Q92805 Golgin subfamily A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 99 582 77 77 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 115 854 96 96 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
GRWD1 GRWD1 Q9BQ67 Glutamate-rich WD repeat-containing protein 1 chr19 Not Cancer Driver No 1 hippie 44 187 14 14 0
HERC2 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 Compendium Yes 1 hippie 718 971 150 150 1
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie, biogrid 24 200 13 13 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 149 251 52 52 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 61 82 6 6 2
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 47 9 0 0 1
IFITM1_ENST00000528780 IFITM1 P13164 Interferon-induced transmembrane protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 19 0 0 0 0
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 36 29 7 7 0
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 70 6 1 1 0
INSL5 INSL5 Q9Y5Q6 Insulin-like peptide INSL5 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 27 56 7 7 0
INSYN1 INSYN1 Q2T9L4 Inhibitory synaptic factor 1 chr15 Not Cancer Driver No 1 hippie 44 253 41 41 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 254 97 27 27 0
KCMF1 KCMF1 Q9P0J7 E3 ubiquitin-protein ligase KCMF1 chr2 Not Cancer Driver No 2 hippie, biogrid 48 270 36 36 0
KRT8_ENST00000546897 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 hippie, biogrid 65 221 37 37 3
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 47 93 10 10 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LY6G5C LY6G5C Q5SRR4 Lymphocyte antigen 6 complex locus protein G5c chr6 Not Cancer Driver No 1 hippie, biogrid 12 1 0 0 0
LYPD6B_ENST00000409876 LYPD6B Q8NI32 Ly6/PLAUR domain-containing protein 6B chr2 Not Cancer Driver No 1 hippie, biogrid 35 3 4 4 0
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 hippie, biogrid 136 589 92 92 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MCRS1_ENST00000550165 MCRS1 Q96EZ8 Microspherule protein 1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 72 151 18 18 0
METTL2A METTL2A Q96IZ6 tRNA N(3)-methylcytidine methyltransferase METTL2A chr17 Not Cancer Driver No 2 intact, hippie, biogrid 38 79 12 12 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 intact 226 62 15 15 19
MFN2_ENST00000444836 MFN2 O95140 Mitofusin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 80 81 9 9 20
MIGA2 MIGA2 Q7L4E1 Mitoguardin 2 chr9 Not Cancer Driver No 1 intact, hippie 55 184 19 19 0
MIOX MIOX Q9UGB7 Inositol oxygenase chr22 Not Cancer Driver No 1 hippie, biogrid 48 21 4 4 0
MOB4 MOB4 Q9Y3A3 MOB-like protein phocein chr2 Not Cancer Driver No 1 hippie 23 34 5 5 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MRPS12_ENST00000402029 MRPS12 O15235 28S ribosomal protein S12, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 18 59 11 11 0
MTNR1A MTNR1A P48039 Melatonin receptor type 1A chr4 Not Cancer Driver No 1 intact, hippie 72 0 0 0 0
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 Not Cancer Driver No 1 intact, hippie 104 8 1 1 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NBR1 NBR1 Q14596 Next to BRCA1 gene 1 protein chr17 Not Cancer Driver No 1 hippie 101 560 51 51 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 intact, hippie 48 111 17 17 0
NHLRC2 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 74 103 12 12 0
NME3 NME3 Q13232 Nucleoside diphosphate kinase 3 chr16 Not Cancer Driver No 1 hippie, biogrid 10 4 0 0 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NRBP2 NRBP2 Q9NSY0 Nuclear receptor-binding protein 2 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 30 110 5 5 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 Compendium Yes 2 hippie, biogrid 146 211 31 31 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 50 10 5 5 0
PGRMC1 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie 30 74 16 16 0
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 Not Cancer Driver No 1 hippie 48 50 6 6 4
PI4KA PI4KA P42356 Phosphatidylinositol 4-kinase alpha chr22 Not Cancer Driver No 1 hippie, biogrid 267 142 11 11 1
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PNPLA1 PNPLA1 Q8N8W4 Omega-hydroxyceramide transacylase chr6 Not Cancer Driver No 2 intact, hippie, biogrid 89 253 48 48 2
POGLUT1 POGLUT1 Q8NBL1 Protein O-glucosyltransferase 1 chr3 Not Cancer Driver No 1 hippie, biogrid 57 0 0 0 3
POMC POMC P01189 Pro-opiomelanocortin chr2 Not Cancer Driver No 2 intact, hippie, biogrid 50 198 38 38 0
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 Census Yes 1 hippie 36 186 12 12 0
PPM1M_ENST00000323588 PPM1M Q96MI6 Protein phosphatase 1M chr3 Not Cancer Driver No 1 hippie, biogrid 23 87 2 2 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 Census Yes 1 hippie 201 189 33 33 2
PRMT6 PRMT6 Q96LA8 Protein arginine N-methyltransferase 6 chr1 Not Cancer Driver No 1 hippie, biogrid 43 71 7 7 0
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 Not Cancer Driver No 1 hippie 71 109 16 16 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
PSKH1 PSKH1 P11801 Serine/threonine-protein kinase H1 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 56 122 24 24 0
PSMB2 PSMB2 P49721 Proteasome subunit beta type-2 chr1 Not Cancer Driver No 1 hippie 24 0 0 0 0
PSMC5 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 Not Cancer Driver No 1 hippie 52 64 6 6 0
PSMC6_ENST00000606149 PSMC6 P62333 26S proteasome regulatory subunit 10B chr14 Not Cancer Driver No 1 hippie 49 69 8 8 0
PSMD13_ENST00000532097 PSMD13 Q9UNM6 26S proteasome non-ATPase regulatory subunit 13 chr11 Not Cancer Driver No 1 hippie 30 13 3 3 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 23 67 6 6 0
PTX3 PTX3 P26022 Pentraxin-related protein PTX3 chr3 Not Cancer Driver No 1 hippie, biogrid 39 74 2 2 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie 32 65 15 15 0
RAD23A RAD23A P54725 UV excision repair protein RAD23 homolog A chr19 Not Cancer Driver No 1 hippie 50 283 41 41 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 65 159 17 17 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 Not Cancer Driver No 1 hippie 26 14 3 3 0
RAPSN RAPSN Q13702 43 kDa receptor-associated protein of the synapse chr11 Not Cancer Driver No 1 hippie, biogrid 38 10 0 0 8
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 Census, Compendium Yes 1 hippie 140 282 32 32 22
RMND5A RMND5A Q9H871 E3 ubiquitin-protein transferase RMND5A chr2 Not Cancer Driver No 1 hippie 46 0 0 0 0
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
RNF181 RNF181 Q9P0P0 E3 ubiquitin-protein ligase RNF181 chr2 Not Cancer Driver No 1 hippie 15 63 8 8 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 Not Cancer Driver No 1 hippie 94 178 32 32 0
RPS6KL1_ENST00000557413 RPS6KL1 Q9Y6S9 Ribosomal protein S6 kinase-like 1 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 60 161 16 16 0
SARS2_ENST00000221431 SARS2 Q9NP81 Serine--tRNA ligase, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 64 111 14 14 1
SART3 SART3 Q15020 Squamous cell carcinoma antigen recognized by T-cells 3 chr12 Not Cancer Driver No 1 hippie, biogrid 101 404 45 45 0
SASS6 SASS6 Q6UVJ0 Spindle assembly abnormal protein 6 homolog chr1 Not Cancer Driver No 2 intact, hippie, biogrid 82 331 37 37 1
SBNO1 SBNO1 A3KN83 Protein strawberry notch homolog 1 chr12 Not Cancer Driver No 1 hippie, biogrid 189 569 68 68 0
SCO1 SCO1 O75880 Protein SCO1 homolog, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 35 79 7 7 1
SEM1_ENST00000356686 SEM1 Q6ZVN7 Putative protein SEM1, isoform 2 chr7 Not Cancer Driver No 1 hippie 2 52 1 1 0
SERPINH1_ENST00000358171 SERPINH1 P50454 Serpin H1 chr11 Not Cancer Driver No 1 intact, hippie 51 52 6 6 1
SH3RF1 SH3RF1 Q7Z6J0 E3 ubiquitin-protein ligase SH3RF1 chr4 Not Cancer Driver No 1 hippie 109 586 72 72 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 58 5 5 1
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SLC15A3 SLC15A3 Q8IY34 Solute carrier family 15 member 3 chr11 Not Cancer Driver No 1 intact, hippie 63 43 1 1 0
SLX1A_ENST00000345535 SLX1A Q9BQ83-2 Isoform 2 of Structure-specific endonuclease subunit SLX1 chr16 Not Cancer Driver No 1 hippie, biogrid 5 27 0 0 0
SNRNP200 SNRNP200 O75643 U5 small nuclear ribonucleoprotein 200 kDa helicase chr2 Not Cancer Driver No 1 hippie, biogrid 237 270 37 37 11
SOHLH1_ENST00000298466 SOHLH1 Q5JUK2 Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 48 252 39 39 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 intact, hippie 39 312 39 39 0
SPATA1 SPATA1 Q5VX52 Spermatogenesis-associated protein 1 chr1 Not Cancer Driver No 1 biogrid 32 160 11 11 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 intact, hippie 71 194 35 35 2
SRGN SRGN P10124 Serglycin chr10 Not Cancer Driver No 1 hippie 25 87 13 13 0
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 Not Cancer Driver No 1 hippie 78 343 46 46 0
STAT2 STAT2 P52630 Signal transducer and activator of transcription 2 chr12 Not Cancer Driver No 1 hippie 90 178 22 22 2
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STK32C STK32C Q86UX6 Serine/threonine-protein kinase 32C chr10 Not Cancer Driver No 2 hippie, biogrid 49 172 10 10 0
STK38 STK38 Q15208 Serine/threonine-protein kinase 38 chr6 Not Cancer Driver No 1 hippie, biogrid 57 77 6 6 0
STX11 STX11 O75558 Syntaxin-11 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 71 48 7 7 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 Census Yes 1 intact, hippie 54 305 53 53 0
TBC1D32 TBC1D32 Q96NH3 Protein broad-minded chr6 Not Cancer Driver No 1 hippie 173 110 19 19 0
TES TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 56 100 7 7 0
TFDP3 TFDP3 Q5H9I0 Transcription factor Dp family member 3 chrX Not Cancer Driver No 3 intact, hippie, biogrid 84 186 42 42 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 1 hippie, biogrid 89 80 6 6 1
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 intact, hippie 51 399 46 46 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 Not Cancer Driver No 1 hippie, biogrid 43 3 1 1 5
TMPRSS11B TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 95 5 0 0 0
TMPRSS2_ENST00000458356 TMPRSS2 O15393 Transmembrane protease serine 2 chr21 Census Yes 1 hippie, biogrid 66 25 5 5 0
TOP3B_ENST00000357179 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 Not Cancer Driver No 1 hippie, biogrid 102 151 17 17 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TPGS2_ENST00000334295 TPGS2 Q68CL5 Tubulin polyglutamylase complex subunit 2 chr18 Not Cancer Driver No 1 hippie, biogrid 28 107 9 9 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TUBGCP3 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 1 hippie 109 156 16 16 0
TXNIP TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 Not Cancer Driver No 1 hippie 61 77 14 14 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX Compendium Yes 1 intact, hippie 35 67 13 13 2
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 Not Cancer Driver No 1 hippie 13 68 6 6 0
UBE2D2 UBE2D2 P62837 Ubiquitin-conjugating enzyme E2 D2 chr5 Compendium Yes 1 hippie 19 13 1 1 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 Not Cancer Driver No 1 hippie 19 32 4 4 0
UBXN1_ENST00000301935 UBXN1 Q04323 UBX domain-containing protein 1 chr11 Not Cancer Driver No 1 intact, hippie 35 271 33 33 0
UBXN7 UBXN7 O94888 UBX domain-containing protein 7 chr3 Not Cancer Driver No 1 hippie 65 327 39 39 0
UHMK1 UHMK1 Q8TAS1 Serine/threonine-protein kinase Kist chr1 Not Cancer Driver No 1 intact, hippie, biogrid 42 14 2 2 0
UNC93B1 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 1 intact, hippie 57 127 5 5 0
UPP1_ENST00000395564 UPP1 Q16831 Uridine phosphorylase 1 chr7 Not Cancer Driver No 1 hippie, biogrid 47 13 3 3 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 Not Cancer Driver No 1 hippie 52 271 44 44 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 1 intact 170 215 45 45 0
USP9X_ENST00000378308 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX Census, Compendium Yes 1 hippie, biogrid 339 405 51 51 1
VASP VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 1 hippie, biogrid 39 335 34 34 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 2 intact, hippie 188 110 28 28 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VEGFD VEGFD O43915 Vascular endothelial growth factor D chrX Not Cancer Driver No 2 intact, hippie 59 33 6 6 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie, biogrid 84 316 57 57 1
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VWA5A VWA5A O00534 von Willebrand factor A domain-containing protein 5A chr11 Not Cancer Driver No 1 intact, hippie, biogrid 145 137 37 37 0
WDR34 DYNC2I2 Q96EX3 Cytoplasmic dynein 2 intermediate chain 2 chr9 Not Cancer Driver No 1 intact 50 123 10 10 10
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 Not Cancer Driver No 1 intact, hippie 24 35 2 2 1
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 Census, Compendium Yes 1 hippie, biogrid 246 831 200 200 8
ZHX1-C8orf76 ZHX1-C8orf76 Q96EF9 Zinc fingers and homeoboxes protein 1, isoform 2 chr8 Not Cancer Driver No 1 hippie, biogrid 28 21 0 0 0
ZNHIT2 ZNHIT2 Q9UHR6 Zinc finger HIT domain-containing protein 2 chr11 Not Cancer Driver No 1 hippie, biogrid 29 157 15 15 0
ZRANB1 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 Not Cancer Driver No 1 hippie 87 158 25 25 0
ZUP1 ZUP1 Q96AP4 Zinc finger-containing ubiquitin peptidase 1 chr6 Not Cancer Driver No 1 hippie 63 204 19 19 0