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UBE2U_ENST00000611228 ,UBE2U ,Q5VVX9
  • Uniprot Accession= Q5VVX9
  • Ensembl Transcript= ENST00000611228.4
  • Uniprot Name= UBE2U
  • Name= Ubiquitin-conjugating enzyme E2 U
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 50
  • Number of Interaction partner in biogrid: 76
  • Number of Interaction partner in hippie: 131
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
A1BG A1BG P04217 Alpha-1B-glycoprotein chr19 Not Cancer Driver No 1 hippie, biogrid 57 155 20 20 0
A2M A2M P01023 Alpha-2-macroglobulin chr12 Not Cancer Driver No 1 hippie, biogrid 260 144 22 22 0
AGT AGT P01019 Angiotensinogen chr1 Not Cancer Driver No 1 hippie, biogrid 85 33 10 10 1
AHSG AHSG P02765 Alpha-2-HS-glycoprotein chr3 Not Cancer Driver No 1 hippie, biogrid 74 131 41 41 0
ALB ALB P02768 Albumin chr4 Compendium Yes 1 hippie, biogrid 162 6 0 0 3
ANAPC11_ENST00000579978 ANAPC11 Q9NYG5 Anaphase-promoting complex subunit 11 chr17 Not Cancer Driver No 1 intact, hippie 7 0 0 0 0
APCS APCS P02743 Serum amyloid P-component chr1 Not Cancer Driver No 1 hippie, biogrid 73 0 0 0 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 Not Cancer Driver No 1 hippie, biogrid 28 131 8 8 3
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 Not Cancer Driver No 1 hippie, biogrid 13 0 0 0 0
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 Not Cancer Driver No 1 hippie, biogrid 77 298 65 65 0
APOB APOB P04114 Apolipoprotein B-100 chr2 Not Cancer Driver No 1 hippie, biogrid 1022 315 72 72 3
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 Census Yes 1 intact, hippie 96 384 49 49 0
BFAR BFAR Q9NZS9 Bifunctional apoptosis regulator chr16 Not Cancer Driver No 1 intact, hippie 56 30 1 1 0
C1QB C1QB P02746 Complement C1q subcomponent subunit B chr1 Not Cancer Driver No 1 hippie, biogrid 46 133 31 31 1
C3 C3 P01024 Complement C3 chr19 Not Cancer Driver No 1 hippie, biogrid 337 287 50 50 12
C4BPA C4BPA P04003 C4b-binding protein alpha chain chr1 Not Cancer Driver No 1 hippie, biogrid 109 40 10 10 0
C5 C5 P01031 Complement C5 chr9 Not Cancer Driver No 1 hippie, biogrid 192 84 9 9 0
C9 C9 P02748 Complement component C9 chr5 Not Cancer Driver No 1 hippie, biogrid 156 40 8 8 2
CADPS2 CADPS2 Q86UW7 Calcium-dependent secretion activator 2 chr7 Not Cancer Driver No 1 hippie 194 202 22 22 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 hippie 115 512 56 56 4
CFB CFB P00751 Complement factor B chr6 Not Cancer Driver No 1 hippie, biogrid 75 112 20 20 7
CFH CFH P08603 Complement factor H chr1 Not Cancer Driver No 1 hippie, biogrid 355 89 28 28 42
CGRRF1 CGRRF1 Q99675 Cell growth regulator with RING finger domain protein 1 chr14 Not Cancer Driver No 1 intact, hippie 31 34 5 5 0
CP CP P00450 Ceruloplasmin chr3 Not Cancer Driver No 1 hippie, biogrid 145 197 30 30 0
DTX1 DTX1 Q86Y01 E3 ubiquitin-protein ligase DTX1 chr12 Compendium Yes 1 intact, hippie 107 304 43 43 0
DZIP3_ENST00000463306 DZIP3 Q86Y13 E3 ubiquitin-protein ligase DZIP3 chr3 Not Cancer Driver No 1 hippie, biogrid 177 370 68 68 0
F2 F2 P00734 Prothrombin chr11 Not Cancer Driver No 1 hippie, biogrid 115 97 25 25 10
FGA FGA P02671 Fibrinogen alpha chain chr4 Not Cancer Driver No 1 hippie, biogrid 245 522 149 149 7
FGB FGB P02675 Fibrinogen beta chain chr4 Not Cancer Driver No 1 hippie, biogrid 89 143 29 29 7
FGG FGG P02679 Fibrinogen gamma chain chr4 Not Cancer Driver No 1 hippie, biogrid 81 53 8 8 8
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie, biogrid 394 1243 185 185 8
GC_ENST00000273951 GC P02774 Vitamin D-binding protein chr4 Not Cancer Driver No 1 hippie, biogrid 93 13 3 3 0
GNB2 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 Not Cancer Driver No 1 intact, hippie 50 21 0 0 7
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 intact, hippie 115 854 96 96 0
HBB HBB P68871 Hemoglobin subunit beta chr11 Not Cancer Driver No 1 hippie, biogrid 45 7 2 2 5
HP HP P00738 Haptoglobin chr16 Not Cancer Driver No 1 hippie, biogrid 39 57 2 2 1
HPX HPX P02790 Hemopexin chr11 Not Cancer Driver No 1 hippie, biogrid 60 53 8 8 0
HRG HRG P04196 Histidine-rich glycoprotein chr3 Not Cancer Driver No 1 hippie, biogrid 121 277 75 75 2
IGLL5 IGLL5 B9A064 Immunoglobulin lambda-like polypeptide 5 chr22 Not Cancer Driver No 1 hippie, biogrid 59 127 35 35 0
ITIH1 ITIH1 P19827 Inter-alpha-trypsin inhibitor heavy chain H1 chr3 Not Cancer Driver No 1 hippie, biogrid 166 180 48 48 0
ITIH2 ITIH2 P19823 Inter-alpha-trypsin inhibitor heavy chain H2 chr10 Not Cancer Driver No 1 hippie, biogrid 204 110 24 24 0
ITIH4 ITIH4 Q14624 Inter-alpha-trypsin inhibitor heavy chain H4 chr3 Not Cancer Driver No 1 hippie, biogrid 103 264 39 39 0
KAT6A_ENST00000406337 KAT6A Q92794 Histone acetyltransferase KAT6A chr8 Census, Compendium Yes 1 intact, hippie 273 1420 193 193 0
KLK6 KLK6 Q92876 Kallikrein-6 chr19 Not Cancer Driver No 1 hippie, biogrid 62 28 12 12 0
KNG1 KNG1 P01042 Kininogen-1 chr3 Not Cancer Driver No 1 hippie, biogrid 130 294 66 66 1
LCN2_ENST00000277480 LCN2 P80188 Neutrophil gelatinase-associated lipocalin chr9 Not Cancer Driver No 1 hippie, biogrid 29 4 3 3 0
LRG1 LRG1 P02750 Leucine-rich alpha-2-glycoprotein chr19 Not Cancer Driver No 1 hippie, biogrid 63 29 8 8 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 intact, hippie 56 297 37 37 0
MIB1 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 Not Cancer Driver No 1 intact, hippie 122 282 34 34 1
MIB2_ENST00000504599 MIB2 Q96AX9 E3 ubiquitin-protein ligase MIB2 chr1 Not Cancer Driver No 1 intact, hippie 88 307 31 31 0
MID2 MID2 Q9UJV3 Probable E3 ubiquitin-protein ligase MID2 chrX Not Cancer Driver No 1 hippie 112 95 24 24 1
MKRN3 MKRN3 Q13064 Probable E3 ubiquitin-protein ligase makorin-3 chr15 Not Cancer Driver No 1 hippie, biogrid 197 201 99 99 4
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 Not Cancer Driver No 1 hippie 48 16 2 2 0
MVB12A MVB12A Q96EY5 Multivesicular body subunit 12A chr19 Not Cancer Driver No 2 intact, hippie, biogrid 27 67 4 4 0
ORM1 ORM1 P02763 Alpha-1-acid glycoprotein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 38 23 2 2 0
ORM2 ORM2 P19652 Alpha-1-acid glycoprotein 2 chr9 Not Cancer Driver No 1 hippie, biogrid 38 22 2 2 0
PCGF1 PCGF1 Q9BSM1 Polycomb group RING finger protein 1 chr2 Not Cancer Driver No 1 hippie 28 8 0 0 0
PCGF6 PCGF6 Q9BYE7 Polycomb group RING finger protein 6 chr10 Not Cancer Driver No 1 hippie, biogrid 29 142 11 11 0
PJA1 PJA1 Q8NG27 E3 ubiquitin-protein ligase Praja-1 chrX Not Cancer Driver No 1 hippie 112 525 94 94 0
PLG PLG P00747 Plasminogen chr6 Not Cancer Driver No 1 hippie, biogrid 242 230 64 64 9
PML PML P29590 Protein PML chr15 Census, Compendium Yes 1 intact, hippie 112 312 34 34 0
PON1 PON1 P27169 Serum paraoxonase/arylesterase 1 chr7 Not Cancer Driver No 1 hippie, biogrid 80 10 9 9 0
RBCK1 RBCK1 Q9BYM8 RanBP-type and C3HC4-type zinc finger-containing protein 1 chr20 Not Cancer Driver No 1 intact, hippie, biogrid 52 140 14 14 2
RBP4 RBP4 P02753 Retinol-binding protein 4 chr10 Not Cancer Driver No 1 hippie, biogrid 30 8 1 1 4
RNF10_ENST00000325954 RNF10 Q8N5U6 RING finger protein 10 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 108 455 63 63 0
RNF11 RNF11 Q9Y3C5 RING finger protein 11 chr1 Not Cancer Driver No 1 hippie 17 76 7 7 0
RNF113A RNF113A O15541 E3 ubiquitin-protein ligase RNF113A chrX Not Cancer Driver No 1 intact, hippie 61 226 51 51 0
RNF113B RNF113B Q8IZP6 RING finger protein 113B chr13 Not Cancer Driver No 1 hippie 56 170 34 34 0
RNF114 RNF114 Q9Y508 E3 ubiquitin-protein ligase RNF114 chr20 Not Cancer Driver No 1 hippie 19 14 2 2 0
RNF125 RNF125 Q96EQ8 E3 ubiquitin-protein ligase RNF125 chr18 Not Cancer Driver No 1 intact, hippie, biogrid 35 26 1 1 3
RNF139 RNF139 Q8WU17 E3 ubiquitin-protein ligase RNF139 chr8 Not Cancer Driver No 1 hippie 76 68 4 4 0
RNF14 RNF14 Q9UBS8 E3 ubiquitin-protein ligase RNF14 chr5 Not Cancer Driver No 1 intact, hippie 52 40 8 8 0
RNF144B RNF144B Q7Z419 E3 ubiquitin-protein ligase RNF144B chr6 Not Cancer Driver No 2 intact, hippie, biogrid 32 4 1 1 0
RNF150 RNF150 Q9ULK6 RING finger protein 150 chr4 Not Cancer Driver No 1 intact, hippie 72 144 15 15 0
RNF166 RNF166 Q96A37 E3 ubiquitin-protein ligase RNF166 chr16 Not Cancer Driver No 1 intact, hippie 18 24 2 2 0
RNF17 RNF17 Q9BXT8 RING finger protein 17 chr13 Not Cancer Driver No 1 intact, hippie 292 290 39 39 0
RNF170_ENST00000527424 RNF170 Q96K19 E3 ubiquitin-protein ligase RNF170 chr8 Not Cancer Driver No 1 intact, hippie 14 0 0 0 1
RNF181 RNF181 Q9P0P0 E3 ubiquitin-protein ligase RNF181 chr2 Not Cancer Driver No 1 intact, hippie 15 63 8 8 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RNF213 RNF213 Q63HN8 E3 ubiquitin-protein ligase RNF213 chr17 Census, Compendium Yes 1 hippie 560 623 75 75 3
RNF25 RNF25 Q96BH1 E3 ubiquitin-protein ligase RNF25 chr2 Not Cancer Driver No 1 intact, hippie 56 285 42 42 0
RNF26 RNF26 Q9BY78 E3 ubiquitin-protein ligase RNF26 chr11 Not Cancer Driver No 1 intact, hippie 44 71 7 7 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 Not Cancer Driver No 1 intact, hippie 44 33 2 2 0
RNF5 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 Not Cancer Driver No 1 intact, hippie 17 69 3 3 0
RNFT1 RNFT1 Q5M7Z0 E3 ubiquitin-protein ligase RNFT1 chr17 Not Cancer Driver No 1 intact, hippie 37 117 18 18 0
RPSA_ENST00000301821 RPSA P08865 40S ribosomal protein SA chr3 Not Cancer Driver No 1 intact, hippie 22 95 6 6 5
SAA2_ENST00000529528 SAA2 P0DJI9 Serum amyloid A-2 protein chr11 Not Cancer Driver No 1 biogrid 31 39 12 12 0
SAA4 SAA4 P35542 Serum amyloid A-4 protein chr11 Not Cancer Driver No 1 hippie, biogrid 19 28 5 5 0
SERPINA1 SERPINA1 P01009 Alpha-1-antitrypsin chr14 Not Cancer Driver No 1 hippie, biogrid 66 38 7 7 0
SERPINA3_ENST00000393080 SERPINA3 P01011 Alpha-1-antichymotrypsin chr14 Not Cancer Driver No 1 hippie, biogrid 117 18 10 10 0
SERPINA6 SERPINA6 P08185 Corticosteroid-binding globulin chr14 Not Cancer Driver No 1 hippie, biogrid 85 0 0 0 2
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 Not Cancer Driver No 1 hippie, biogrid 142 47 28 28 0
SERPINB4 SERPINB4 P48594 Serpin B4 chr18 Not Cancer Driver No 1 hippie, biogrid 120 48 18 18 0
SERPINC1 SERPINC1 P01008 Antithrombin-III chr1 Not Cancer Driver No 1 hippie, biogrid 84 29 8 8 84
SERPIND1_ENST00000406799 SERPIND1 P05546 Heparin cofactor 2 chr22 Not Cancer Driver No 1 hippie, biogrid 69 50 7 7 3
SERPINF1 SERPINF1 P36955 Pigment epithelium-derived factor chr17 Not Cancer Driver No 1 hippie, biogrid 51 57 5 5 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 Not Cancer Driver No 1 hippie, biogrid 62 112 21 21 1
SERPING1 SERPING1 P05155 Plasma protease C1 inhibitor chr11 Not Cancer Driver No 1 hippie, biogrid 74 113 13 13 40
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 Not Cancer Driver No 1 hippie 63 284 32 32 0
TF TF P02787 Serotransferrin chr3 Not Cancer Driver No 1 hippie, biogrid 135 21 5 5 2
TRAIP TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 Not Cancer Driver No 1 intact, hippie 63 240 33 33 1
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 69 79 11 11 0
TRIM23 TRIM23 P36406 E3 ubiquitin-protein ligase TRIM23 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 91 39 2 2 0
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 Census, Compendium Yes 1 intact, hippie 120 537 61 61 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 intact, hippie, biogrid 59 87 11 11 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 intact, hippie 87 430 41 41 0
TRIM2_ENST00000437508 TRIM2 Q9C040 Tripartite motif-containing protein 2 chr4 Not Cancer Driver No 1 hippie 86 238 38 38 1
TRIM3 TRIM3 O75382 Tripartite motif-containing protein 3 chr11 Not Cancer Driver No 1 intact, hippie 108 253 37 37 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 82 87 10 10 3
TRIM34_ENST00000429814 TRIM34 Q9BYJ4 Tripartite motif-containing protein 34 chr11 Not Cancer Driver No 1 intact, hippie 74 32 2 2 0
TRIM35 TRIM35 Q9UPQ4 E3 ubiquitin-protein ligase TRIM35 chr8 Not Cancer Driver No 1 intact, hippie 66 69 9 9 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
TRIM38 TRIM38 O00635 E3 ubiquitin-protein ligase TRIM38 chr6 Not Cancer Driver No 1 intact, hippie 62 47 8 8 0
TRIM46 TRIM46 Q7Z4K8 Tripartite motif-containing protein 46 chr1 Not Cancer Driver No 1 hippie, biogrid 115 173 30 30 0
TRIM47 TRIM47 Q96LD4 E3 ubiquitin-protein ligase TRIM47 chr17 Not Cancer Driver No 1 intact, hippie 38 202 9 9 0
TRIM5 TRIM5 Q9C035 Tripartite motif-containing protein 5 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 71 77 11 11 0
TRIM54_ENST00000380075 TRIM54 Q9BYV2 Tripartite motif-containing protein 54 chr2 Not Cancer Driver No 1 intact, hippie 63 98 17 17 0
TRIM63 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 Not Cancer Driver No 1 hippie 47 71 13 13 0
TRIM65 TRIM65 Q6PJ69 Tripartite motif-containing protein 65 chr17 Not Cancer Driver No 1 intact, hippie 53 127 13 13 0
TRIM68 TRIM68 Q6AZZ1 E3 ubiquitin-protein ligase TRIM68 chr11 Not Cancer Driver No 1 intact, hippie 74 37 7 7 0
TRIM74 TRIM74 Q86UV6 Tripartite motif-containing protein 74 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 25 12 1 1 0
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 Not Cancer Driver No 1 hippie, biogrid 46 159 23 23 0
TTR TTR P02766 Transthyretin chr18 Not Cancer Driver No 1 hippie, biogrid 28 25 8 8 75
UBA1 UBA1 P22314 Ubiquitin-like modifier-activating enzyme 1 chrX Not Cancer Driver No 1 hippie 117 165 22 22 6
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 142 117 36 36 133
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie, biogrid 84 316 57 57 1
VPS11 VPS11 Q9H270 Vacuolar protein sorting-associated protein 11 homolog chr11 Not Cancer Driver No 1 intact, hippie, biogrid 96 118 6 6 1
VPS28_ENST00000292510 VPS28 Q9UK41 Vacuolar protein sorting-associated protein 28 homolog chr8 Not Cancer Driver No 3 intact, hippie, biogrid 28 31 5 5 0
VPS37C VPS37C A5D8V6 Vacuolar protein sorting-associated protein 37C chr11 Not Cancer Driver No 1 hippie, biogrid 34 309 31 31 0
VPS41 VPS41 P49754 Vacuolar protein sorting-associated protein 41 homolog chr7 Not Cancer Driver No 1 intact, hippie 116 45 12 12 2
VTN VTN P04004 Vitronectin chr17 Not Cancer Driver No 1 hippie, biogrid 76 168 29 29 0
ZSWIM2 ZSWIM2 Q8NEG5 E3 ubiquitin-protein ligase ZSWIM2 chr2 Not Cancer Driver No 1 hippie 189 85 30 30 0