Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACAT1 | ACAT1 | P24752 | Acetyl-CoA acetyltransferase, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 32 | 1 | 1 | 10 |
AGO1 | AGO1 | Q9UL18 | Protein argonaute-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 126 | 87 | 11 | 11 | 0 |
AGO2 | AGO2 | Q9UKV8 | Protein argonaute-2 | chr8 | Not Cancer Driver | No | 1 | hippie | 126 | 141 | 15 | 15 | 11 |
AGO3 | AGO3 | Q9H9G7 | Protein argonaute-3 | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 143 | 19 | 19 | 0 |
ALG13 | ALG13 | Q9NP73 | Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 | chrX | Not Cancer Driver | No | 1 | hippie | 163 | 520 | 83 | 83 | 2 |
ANKRD17 | ANKRD17 | O75179 | Ankyrin repeat domain-containing protein 17 | chr4 | Not Cancer Driver | No | 1 | hippie | 312 | 1790 | 221 | 221 | 9 |
ANLN | ANLN | Q9NQW6 | Anillin | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 144 | 767 | 104 | 104 | 2 |
AR | AR | P10275 | Androgen receptor | chrX | Census, Compendium | Yes | 1 | hippie | 196 | 443 | 88 | 88 | 169 |
ARHGEF10L | ARHGEF10L | Q9HCE6 | Rho guanine nucleotide exchange factor 10-like protein | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 155 | 431 | 47 | 47 | 0 |
ARHGEF15 | ARHGEF15 | O94989 | Rho guanine nucleotide exchange factor 15 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 156 | 536 | 97 | 97 | 0 |
ARIH1 | ARIH1 | Q9Y4X5 | E3 ubiquitin-protein ligase ARIH1 | chr15 | Not Cancer Driver | No | 1 | hippie | 46 | 119 | 7 | 7 | 0 |
ATXN1 | ATXN1 | P54253 | Ataxin-1 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 193 | 604 | 168 | 168 | 0 |
ATXN2L_ENST00000336783 | ATXN2L | Q8WWM7 | Ataxin-2-like protein | chr16 | Not Cancer Driver | No | 1 | hippie | 135 | 1000 | 131 | 131 | 0 |
ATXN2_ENST00000550104 | ATXN2 | Q99700 | Ataxin-2 | chr12 | Not Cancer Driver | No | 1 | hippie | 146 | 1228 | 134 | 134 | 0 |
BAG3 | BAG3 | O95817 | BAG family molecular chaperone regulator 3 | chr10 | Not Cancer Driver | No | 1 | hippie | 57 | 571 | 57 | 57 | 7 |
BCAR1_ENST00000162330 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 108 | 677 | 75 | 75 | 0 |
BCOR | BCOR | Q6W2J9 | BCL-6 corepressor | chrX | Census, Compendium | Yes | 1 | intact, hippie | 291 | 1285 | 226 | 226 | 1 |
BICC1 | BICC1 | Q9H694 | Protein bicaudal C homolog 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 171 | 645 | 115 | 115 | 1 |
BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
BMI1 | BMI1 | P35226 | Polycomb complex protein BMI-1 | chr10 | Not Cancer Driver | No | 2 | intact, hippie | 50 | 150 | 30 | 30 | 0 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
BTF3 | BTF3 | P20290 | Transcription factor BTF3 | chr5 | Not Cancer Driver | No | 1 | hippie | 27 | 192 | 24 | 24 | 0 |
C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 14 | 103 | 6 | 6 | 2 |
CAPRIN1_ENST00000532820 | CAPRIN1 | Q14444 | Caprin-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 84 | 603 | 72 | 72 | 0 |
CCNF | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 221 | 23 | 23 | 3 |
CDV3 | CDV3 | Q9UKY7 | Protein CDV3 homolog | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 258 | 16 | 16 | 0 |
CELF1_ENST00000358597 | CELF1 | Q92879 | CUGBP Elav-like family member 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 56 | 166 | 17 | 17 | 0 |
CELF2_ENST00000416382 | CELF2 | O95319 | CUGBP Elav-like family member 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 74 | 170 | 28 | 28 | 0 |
CEP85 | CEP85 | Q6P2H3 | Centrosomal protein of 85 kDa | chr1 | Not Cancer Driver | No | 1 | hippie | 77 | 607 | 60 | 60 | 0 |
CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
CNOT1 | CNOT1 | A5YKK6 | CCR4-NOT transcription complex subunit 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 346 | 464 | 56 | 56 | 12 |
CNOT10_ENST00000328834 | CNOT10 | Q9H9A5 | CCR4-NOT transcription complex subunit 10 | chr3 | Not Cancer Driver | No | 1 | hippie | 69 | 218 | 18 | 18 | 0 |
CNOT11 | CNOT11 | Q9UKZ1 | CCR4-NOT transcription complex subunit 11 | chr2 | Not Cancer Driver | No | 1 | hippie | 53 | 216 | 16 | 16 | 0 |
CNOT2 | CNOT2 | Q9NZN8 | CCR4-NOT transcription complex subunit 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 84 | 354 | 66 | 66 | 0 |
CNOT3 | CNOT3 | O75175 | CCR4-NOT transcription complex subunit 3 | chr19 | Census, Compendium | Yes | 1 | hippie | 120 | 538 | 78 | 78 | 4 |
CNOT4_ENST00000315544 | CNOT4 | O95628 | CCR4-NOT transcription complex subunit 4 | chr7 | Not Cancer Driver | No | 1 | hippie | 73 | 359 | 35 | 35 | 0 |
CNOT6L | CNOT6L | Q96LI5 | CCR4-NOT transcription complex subunit 6-like | chr4 | Not Cancer Driver | No | 1 | hippie | 58 | 37 | 3 | 3 | 0 |
CNOT9_ENST00000273064 | CNOT9 | Q92600 | CCR4-NOT transcription complex subunit 9 | chr2 | Compendium | Yes | 1 | hippie | 42 | 30 | 0 | 0 | 0 |
COPS5 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 32 | 7 | 7 | 0 |
CPEB1_ENST00000611031 | CPEB1 | Q9BZB8 | Cytoplasmic polyadenylation element-binding protein 1 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 90 | 226 | 37 | 37 | 0 |
CPEB4 | CPEB4 | Q17RY0 | Cytoplasmic polyadenylation element-binding protein 4 | chr5 | Not Cancer Driver | No | 1 | hippie | 85 | 443 | 54 | 54 | 0 |
CPSF6_ENST00000435070 | CPSF6 | Q16630 | Cleavage and polyadenylation specificity factor subunit 6 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 484 | 75 | 75 | 0 |
CPSF7_ENST00000394888 | CPSF7 | Q8N684 | Cleavage and polyadenylation specificity factor subunit 7 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 398 | 52 | 52 | 0 |
CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | Census, Compendium | Yes | 1 | intact, hippie | 123 | 167 | 23 | 23 | 3 |
DAZL_ENST00000399444 | DAZL | Q92904 | Deleted in azoospermia-like | chr3 | Not Cancer Driver | No | 1 | hippie | 28 | 128 | 12 | 12 | 0 |
DDX1 | DDX1 | Q92499 | ATP-dependent RNA helicase DDX1 | chr2 | Not Cancer Driver | No | 1 | hippie | 82 | 91 | 15 | 15 | 0 |
DDX58 | DDX58 | O95786 | Antiviral innate immune response receptor RIG-I | chr9 | Not Cancer Driver | No | 1 | hippie | 118 | 61 | 10 | 10 | 2 |
DDX6 | DDX6 | P26196 | Probable ATP-dependent RNA helicase DDX6 | chr11 | Census, Compendium | Yes | 1 | hippie | 44 | 129 | 7 | 7 | 5 |
DICER1 | DICER1 | Q9UPY3 | Endoribonuclease Dicer | chr14 | Census, Compendium | Yes | 1 | intact, hippie | 264 | 362 | 45 | 45 | 4 |
DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 132 | 514 | 82 | 82 | 0 |
DLD | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 67 | 17 | 0 | 0 | 10 |
DOCK3 | DOCK3 | Q8IZD9 | Dedicator of cytokinesis protein 3 | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 365 | 458 | 69 | 69 | 0 |
EFTUD2 | EFTUD2 | Q15029 | 116 kDa U5 small nuclear ribonucleoprotein component | chr17 | Compendium | Yes | 1 | hippie | 132 | 179 | 30 | 30 | 3 |
EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
EIF4E2 | EIF4E2 | O60573 | Eukaryotic translation initiation factor 4E type 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 27 | 80 | 5 | 5 | 0 |
EIF4ENIF1 | EIF4ENIF1 | Q9NRA8 | Eukaryotic translation initiation factor 4E transporter | chr22 | Not Cancer Driver | No | 1 | hippie | 116 | 899 | 101 | 101 | 0 |
ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 69 | 43 | 5 | 5 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 121 | 195 | 27 | 27 | 2 |
ESRP2_ENST00000565858 | ESRP2 | Q9H6T0 | Epithelial splicing regulatory protein 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 79 | 145 | 12 | 12 | 0 |
ETFBKMT_ENST00000412352 | ETFBKMT | Q8IXQ9 | Electron transfer flavoprotein beta subunit lysine methyltransferase | chr12 | Not Cancer Driver | No | 1 | hippie | 25 | 0 | 0 | 0 | 0 |
EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | Census, Compendium | Yes | 1 | hippie | 120 | 284 | 44 | 44 | 11 |
FAM120A | FAM120A | Q9NZB2 | Constitutive coactivator of PPAR-gamma-like protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 123 | 516 | 58 | 58 | 0 |
FAM120C | FAM120C | Q9NX05 | Constitutive coactivator of PPAR-gamma-like protein 2 | chrX | Not Cancer Driver | No | 1 | hippie | 162 | 508 | 77 | 77 | 0 |
FAM98A | FAM98A | Q8NCA5 | Protein FAM98A | chr2 | Not Cancer Driver | No | 1 | hippie | 63 | 314 | 36 | 36 | 0 |
FBL | FBL | P22087 | rRNA 2'-O-methyltransferase fibrillarin | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 145 | 22 | 22 | 0 |
FBP1_ENST00000375326 | FBP1 | P09467 | Fructose-1,6-bisphosphatase 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 33 | 19 | 0 | 0 | 4 |
FBRSL1 | FBRSL1 | Q9HCM7 | Fibrosin-1-like protein | chr12 | Not Cancer Driver | No | 1 | hippie | 22 | 941 | 15 | 15 | 0 |
FBXW11 | FBXW11 | Q9UKB1 | F-box/WD repeat-containing protein 11 | chr5 | Not Cancer Driver | No | 1 | hippie | 75 | 20 | 3 | 3 | 7 |
FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | Census, Compendium | Yes | 1 | hippie | 322 | 230 | 38 | 38 | 0 |
FMR1 | FMR1 | Q06787 | Synaptic functional regulator FMR1 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 124 | 327 | 70 | 70 | 3 |
FN1 | FN1 | P02751 | Fibronectin | chr2 | Compendium | Yes | 1 | hippie | 394 | 1243 | 185 | 185 | 8 |
FUBP3 | FUBP3 | Q96I24 | Far upstream element-binding protein 3 | chr9 | Not Cancer Driver | No | 1 | hippie | 68 | 353 | 51 | 51 | 0 |
FUS | FUS | P35637 | RNA-binding protein FUS | chr16 | Census | Yes | 1 | hippie | 51 | 524 | 51 | 51 | 20 |
FXR1 | FXR1 | P51114 | Fragile X mental retardation syndrome-related protein 1 | chr3 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 88 | 312 | 53 | 53 | 0 |
FXR2 | FXR2 | P51116 | Fragile X mental retardation syndrome-related protein 2 | chr17 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 68 | 388 | 42 | 42 | 0 |
FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 184 | 30 | 30 | 0 |
G3BP1 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | Not Cancer Driver | No | 2 | intact, hippie | 85 | 352 | 65 | 65 | 0 |
G3BP2_ENST00000395719 | G3BP2 | Q9UN86 | Ras GTPase-activating protein-binding protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 64 | 384 | 53 | 53 | 0 |
GIGYF1_ENST00000646601 | GIGYF1 | O75420 | GRB10-interacting GYF protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 138 | 857 | 115 | 115 | 0 |
GTPBP1 | GTPBP1 | O00178 | GTP-binding protein 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 75 | 263 | 26 | 26 | 0 |
HELZ_ENST00000358691 | HELZ | P42694 | Probable helicase with zinc finger domain | chr17 | Not Cancer Driver | No | 1 | hippie | 234 | 873 | 110 | 110 | 0 |
HEXIM1 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | Not Cancer Driver | No | 1 | hippie | 40 | 352 | 40 | 40 | 0 |
HIF1AN | HIF1AN | Q9NWT6 | Hypoxia-inducible factor 1-alpha inhibitor | chr10 | Not Cancer Driver | No | 1 | hippie | 37 | 77 | 9 | 9 | 0 |
HNRNPDL | HNRNPDL | O14979 | Heterogeneous nuclear ribonucleoprotein D-like | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 297 | 36 | 36 | 2 |
HNRNPH1 | HNRNPH1 | P31943 | Heterogeneous nuclear ribonucleoprotein H | chr5 | Not Cancer Driver | No | 1 | hippie | 51 | 169 | 29 | 29 | 0 |
HNRNPL | HNRNPL | P14866 | Heterogeneous nuclear ribonucleoprotein L | chr19 | Not Cancer Driver | No | 1 | hippie | 89 | 283 | 29 | 29 | 0 |
HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | Compendium | Yes | 1 | hippie | 44 | 127 | 9 | 9 | 2 |
IGF2BP2_ENST00000382199 | IGF2BP2 | Q9Y6M1 | Insulin-like growth factor 2 mRNA-binding protein 2 | chr3 | Census | Yes | 1 | hippie | 68 | 237 | 31 | 31 | 0 |
ILK_ENST00000299421 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | Not Cancer Driver | No | 1 | hippie | 45 | 71 | 9 | 9 | 0 |
IMMP1L | IMMP1L | Q96LU5 | Mitochondrial inner membrane protease subunit 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 3 | 0 | 0 | 0 |
IMMP2L_ENST00000452895 | IMMP2L | Q96T52 | Mitochondrial inner membrane protease subunit 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 36 | 29 | 7 | 7 | 0 |
ISG15 | ISG15 | P05161 | Ubiquitin-like protein ISG15 | chr1 | Not Cancer Driver | No | 1 | hippie | 12 | 24 | 2 | 2 | 0 |
ITCH | ITCH | Q96J02 | E3 ubiquitin-protein ligase Itchy homolog | chr20 | Not Cancer Driver | No | 1 | hippie | 95 | 335 | 42 | 42 | 0 |
ITGA4 | ITGA4 | P13612 | Integrin alpha-4 | chr2 | Not Cancer Driver | No | 1 | hippie | 254 | 97 | 27 | 27 | 0 |
JMJD6_ENST00000397625 | JMJD6 | Q6NYC1 | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 133 | 21 | 21 | 0 |
JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
KAT2A | KAT2A | Q92830 | Histone acetyltransferase KAT2A | chr17 | Not Cancer Driver | No | 1 | hippie | 88 | 251 | 17 | 17 | 0 |
KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
KIF20A | KIF20A | O95235 | Kinesin-like protein KIF20A | chr5 | Not Cancer Driver | No | 1 | hippie | 79 | 340 | 40 | 40 | 1 |
LARP4B | LARP4B | Q92615 | La-related protein 4B | chr10 | Census | Yes | 1 | hippie | 127 | 521 | 91 | 91 | 0 |
LARP4_ENST00000398473 | LARP4 | Q71RC2 | La-related protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie | 86 | 486 | 53 | 53 | 0 |
LRRC31 | LRRC31 | Q6UY01 | Leucine-rich repeat-containing protein 31 | chr3 | Not Cancer Driver | No | 1 | hippie | 109 | 80 | 10 | 10 | 0 |
LRRC59 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | Not Cancer Driver | No | 1 | hippie | 33 | 122 | 15 | 15 | 0 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
LSM12 | LSM12 | Q3MHD2 | Protein LSM12 homolog | chr17 | Not Cancer Driver | No | 1 | hippie | 13 | 66 | 7 | 7 | 0 |
LSM14A_ENST00000433627 | LSM14A | Q8ND56 | Protein LSM14 homolog A | chr19 | Census | Yes | 1 | hippie | 67 | 408 | 63 | 63 | 0 |
LSM14B | LSM14B | Q9BX40 | Protein LSM14 homolog B | chr20 | Not Cancer Driver | No | 1 | hippie | 50 | 320 | 42 | 42 | 0 |
MAB21L2 | MAB21L2 | Q9Y586 | Protein mab-21-like 2 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 81 | 6 | 3 | 3 | 5 |
MAGEL2 | MAGEL2 | Q9UJ55 | MAGE-like protein 2 | chr15 | Not Cancer Driver | No | 1 | hippie | 178 | 1010 | 118 | 118 | 0 |
MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | Not Cancer Driver | No | 1 | hippie | 128 | 750 | 126 | 126 | 18 |
MARF1 | MARF1 | Q9Y4F3 | Meiosis regulator and mRNA stability factor 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 199 | 524 | 73 | 73 | 0 |
MCRIP1_ENST00000455127 | MCRIP1 | C9JLW8 | Mapk-regulated corepressor-interacting protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 1 | 83 | 1 | 1 | 0 |
MCRIP2 | MCRIP2 | Q9BUT9 | MAPK regulated corepressor interacting protein 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 8 | 141 | 7 | 7 | 0 |
MED15 | MED15 | Q96RN5 | Mediator of RNA polymerase II transcription subunit 15 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 558 | 72 | 72 | 0 |
MED4 | MED4 | Q9NPJ6 | Mediator of RNA polymerase II transcription subunit 4 | chr13 | Not Cancer Driver | No | 1 | hippie | 29 | 161 | 17 | 17 | 0 |
MEX3A | MEX3A | A1L020 | RNA-binding protein MEX3A | chr1 | Not Cancer Driver | No | 1 | hippie | 46 | 320 | 23 | 23 | 0 |
MEX3B | MEX3B | Q6ZN04 | RNA-binding protein MEX3B | chr15 | Not Cancer Driver | No | 1 | hippie | 85 | 437 | 64 | 64 | 0 |
MKRN2 | MKRN2 | Q9H000 | E3 ubiquitin-protein ligase makorin-2 | chr3 | Not Cancer Driver | No | 1 | hippie | 45 | 145 | 16 | 16 | 0 |
MLH1 | MLH1 | P40692 | DNA mismatch repair protein Mlh1 | chr3 | Census | Yes | 1 | hippie | 92 | 208 | 22 | 22 | 85 |
MTNR1A | MTNR1A | P48039 | Melatonin receptor type 1A | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 72 | 0 | 0 | 0 | 0 |
MTNR1B | MTNR1B | P49286 | Melatonin receptor type 1B | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 104 | 8 | 1 | 1 | 0 |
MTOR | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 379 | 296 | 37 | 37 | 18 |
NAA40 | NAA40 | Q86UY6 | N-alpha-acetyltransferase 40 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 30 | 3 | 3 | 0 |
NBEAL2 | NBEAL2 | Q6ZNJ1 | Neurobeachin-like protein 2 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 295 | 515 | 59 | 59 | 8 |
NDN | NDN | Q99608 | Necdin | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 123 | 117 | 42 | 42 | 0 |
NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | Not Cancer Driver | No | 1 | hippie | 150 | 711 | 79 | 79 | 0 |
NLK | NLK | Q9UBE8 | Serine/threonine-protein kinase NLK | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 54 | 152 | 20 | 20 | 0 |
NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
NUAK1 | NUAK1 | O60285 | NUAK family SNF1-like kinase 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 142 | 357 | 77 | 77 | 0 |
NUFIP2 | NUFIP2 | Q7Z417 | Nuclear fragile X mental retardation-interacting protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 67 | 623 | 62 | 62 | 0 |
NXF1_ENST00000294172 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 100 | 163 | 32 | 32 | 0 |
OBSL1 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 233 | 553 | 60 | 60 | 0 |
OPTN_ENST00000263036 | OPTN | Q96CV9 | Optineurin | chr10 | Not Cancer Driver | No | 1 | hippie | 58 | 470 | 51 | 51 | 6 |
OTUD4_ENST00000447906 | OTUD4 | Q01804 | OTU domain-containing protein 4 | chr4 | Not Cancer Driver | No | 1 | hippie | 148 | 788 | 120 | 120 | 0 |
PABPC1 | PABPC1 | P11940 | Polyadenylate-binding protein 1 | chr8 | Census, Compendium | Yes | 1 | hippie | 100 | 317 | 55 | 55 | 0 |
PABPC4_ENST00000372857 | PABPC4 | Q13310 | Polyadenylate-binding protein 4 | chr1 | Not Cancer Driver | No | 1 | hippie | 89 | 253 | 49 | 49 | 0 |
PAN3 | PAN3 | Q58A45 | PAN2-PAN3 deadenylation complex subunit PAN3 | chr13 | Not Cancer Driver | No | 1 | hippie | 104 | 323 | 35 | 35 | 0 |
PATL1 | PATL1 | Q86TB9 | Protein PAT1 homolog 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 79 | 499 | 49 | 49 | 0 |
PCLAF | PCLAF | Q15004 | PCNA-associated factor | chr15 | Not Cancer Driver | No | 1 | hippie | 20 | 111 | 20 | 20 | 0 |
PEG10_ENST00000617526 | PEG10 | Q86TG7 | Retrotransposon-derived protein PEG10 | chr7 | Not Cancer Driver | No | 1 | hippie | 94 | 246 | 47 | 47 | 0 |
PIH1D1 | PIH1D1 | Q9NWS0 | PIH1 domain-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 157 | 13 | 13 | 0 |
PIK3C2A | PIK3C2A | O00443 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | chr11 | Not Cancer Driver | No | 1 | hippie | 187 | 350 | 43 | 43 | 0 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
PLXNA2 | PLXNA2 | O75051 | Plexin-A2 | chr1 | Not Cancer Driver | No | 1 | hippie | 312 | 142 | 25 | 25 | 0 |
PMS1 | PMS1 | P54277 | PMS1 protein homolog 1 | chr2 | Census | Yes | 1 | hippie | 114 | 283 | 38 | 38 | 0 |
PPT1 | PPT1 | P50897 | Palmitoyl-protein thioesterase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 37 | 0 | 0 | 0 | 23 |
PRKAA1_ENST00000397128 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | Not Cancer Driver | No | 1 | hippie | 72 | 124 | 17 | 17 | 0 |
PRKAB2 | PRKAB2 | O43741 | 5'-AMP-activated protein kinase subunit beta-2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 31 | 110 | 12 | 12 | 0 |
PRMT1 | PRMT1 | Q99873 | Protein arginine N-methyltransferase 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 50 | 18 | 1 | 1 | 0 |
PRRC2A_ENST00000376007 | PRRC2A | P48634 | Protein PRRC2A | chr6 | Not Cancer Driver | No | 1 | hippie | 253 | 2119 | 249 | 249 | 0 |
PRRC2B | PRRC2B | Q5JSZ5 | Protein PRRC2B | chr9 | Not Cancer Driver | No | 1 | hippie | 279 | 2199 | 278 | 278 | 0 |
PRRC2C | PRRC2C | Q9Y520-4 | Isoform 4 of Protein PRRC2C | chr1 | Not Cancer Driver | No | 1 | hippie | 296 | 2713 | 287 | 287 | 0 |
PUM1_ENST00000257075 | PUM1 | Q14671 | Pumilio homolog 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 150 | 640 | 77 | 77 | 3 |
PUM2_ENST00000403432 | PUM2 | Q8TB72 | Pumilio homolog 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 132 | 575 | 83 | 83 | 0 |
R3HDM1_ENST00000264160 | R3HDM1 | Q15032 | R3H domain-containing protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 138 | 986 | 130 | 130 | 0 |
R3HDM2_ENST00000358907 | R3HDM2 | Q9Y2K5 | R3H domain-containing protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 78 | 836 | 66 | 66 | 0 |
RBM39 | RBM39 | Q14498 | RNA-binding protein 39 | chr20 | Compendium | Yes | 1 | hippie | 81 | 228 | 39 | 39 | 0 |
RBM47_ENST00000295971 | RBM47 | A0AV96 | RNA-binding protein 47 | chr4 | Not Cancer Driver | No | 1 | hippie | 143 | 131 | 28 | 28 | 0 |
RBMS1 | RBMS1 | P29558 | RNA-binding motif, single-stranded-interacting protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 55 | 243 | 36 | 36 | 0 |
RBMS2 | RBMS2 | Q15434 | RNA-binding motif, single-stranded-interacting protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 53 | 265 | 38 | 38 | 0 |
RC3H1_ENST00000258349 | RC3H1 | Q5TC82 | Roquin-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 158 | 796 | 115 | 115 | 0 |
RC3H2_ENST00000357244 | RC3H2 | Q9HBD1 | Roquin-2 | chr9 | Not Cancer Driver | No | 1 | hippie | 128 | 703 | 81 | 81 | 0 |
RNF214_ENST00000531452 | RNF214 | Q8ND24 | RING finger protein 214 | chr11 | Not Cancer Driver | No | 1 | hippie | 84 | 528 | 66 | 66 | 0 |
RPL4 | RPL4 | P36578 | 60S ribosomal protein L4 | chr15 | Not Cancer Driver | No | 1 | hippie | 49 | 222 | 31 | 31 | 0 |
RPS20_ENST00000521262 | RPS20 | P60866 | 40S ribosomal protein S20 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 53 | 8 | 8 | 0 |
RPS6 | RPS6 | P62753 | 40S ribosomal protein S6 | chr9 | Not Cancer Driver | No | 1 | hippie | 38 | 150 | 25 | 25 | 0 |
RPTOR | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | Not Cancer Driver | No | 1 | hippie | 176 | 241 | 21 | 21 | 0 |
RTCB | RTCB | Q9Y3I0 | RNA-splicing ligase RtcB homolog | chr22 | Not Cancer Driver | No | 1 | hippie | 57 | 74 | 7 | 7 | 0 |
RTRAF | RTRAF | Q9Y224 | RNA transcription, translation and transport factor protein | chr14 | Not Cancer Driver | No | 1 | hippie | 24 | 35 | 1 | 1 | 0 |
RYBP | RYBP | Q8N488 | RING1 and YY1-binding protein | chr3 | Not Cancer Driver | No | 1 | hippie | 37 | 214 | 37 | 37 | 0 |
SECISBP2 | SECISBP2 | Q96T21 | Selenocysteine insertion sequence-binding protein 2 | chr9 | Not Cancer Driver | No | 1 | hippie | 90 | 565 | 50 | 50 | 1 |
SERBP1 | SERBP1 | Q8NC51 | Plasminogen activator inhibitor 1 RNA-binding protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 408 | 53 | 53 | 0 |
SF3B1 | SF3B1 | O75533 | Splicing factor 3B subunit 1 | chr2 | Census, Compendium | Yes | 1 | hippie, biogrid | 244 | 477 | 80 | 80 | 0 |
SIRT6 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | Not Cancer Driver | No | 1 | hippie | 33 | 164 | 12 | 12 | 0 |
SIRT7 | SIRT7 | Q9NRC8 | NAD-dependent protein deacetylase sirtuin-7 | chr17 | Not Cancer Driver | No | 1 | hippie | 48 | 163 | 15 | 15 | 0 |
SKA3 | SKA3 | Q8IX90 | Spindle and kinetochore-associated protein 3 | chr13 | Not Cancer Driver | No | 1 | hippie | 56 | 230 | 32 | 32 | 0 |
SMAP2 | SMAP2 | Q8WU79 | Stromal membrane-associated protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 50 | 214 | 30 | 30 | 0 |
SMG5 | SMG5 | Q9UPR3 | Nonsense-mediated mRNA decay factor SMG5 | chr1 | Not Cancer Driver | No | 1 | hippie | 132 | 295 | 51 | 51 | 0 |
SMG7_ENST00000347615 | SMG7 | Q92540 | Nonsense-mediated mRNA decay factor SMG7 | chr1 | Not Cancer Driver | No | 1 | hippie | 134 | 664 | 82 | 82 | 0 |
SPOP | SPOP | O43791 | Speckle-type POZ protein | chr17 | Census, Compendium | Yes | 1 | hippie | 147 | 25 | 5 | 5 | 6 |
SQSTM1 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | Not Cancer Driver | No | 1 | hippie | 54 | 267 | 32 | 32 | 30 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
TDRD3_ENST00000196169 | TDRD3 | Q9H7E2 | Tudor domain-containing protein 3 | chr13 | Not Cancer Driver | No | 1 | hippie | 97 | 518 | 77 | 77 | 0 |
TEC | TEC | P42680 | Tyrosine-protein kinase Tec | chr4 | Census, Compendium | Yes | 1 | hippie, biogrid | 91 | 57 | 15 | 15 | 0 |
TLN1 | TLN1 | Q9Y490 | Talin-1 | chr9 | Not Cancer Driver | No | 1 | hippie | 278 | 1109 | 126 | 126 | 0 |
TNRC6A | TNRC6A | Q8NDV7 | Trinucleotide repeat-containing gene 6A protein | chr16 | Not Cancer Driver | No | 1 | hippie | 284 | 1830 | 265 | 265 | 0 |
TNRC6B | TNRC6B | Q9UPQ9 | Trinucleotide repeat-containing gene 6B protein | chr22 | Not Cancer Driver | No | 1 | hippie | 205 | 1735 | 195 | 195 | 0 |
TNRC6C_ENST00000301624 | TNRC6C | Q9HCJ0 | Trinucleotide repeat-containing gene 6C protein | chr17 | Not Cancer Driver | No | 1 | hippie | 170 | 1564 | 162 | 162 | 0 |
TOP3B_ENST00000357179 | TOP3B | O95985 | DNA topoisomerase 3-beta-1 | chr22 | Not Cancer Driver | No | 2 | hippie, biogrid | 102 | 151 | 17 | 17 | 0 |
TPT1_ENST00000530705 | TPT1 | P13693 | Translationally-controlled tumor protein | chr13 | Not Cancer Driver | No | 1 | hippie | 17 | 43 | 6 | 6 | 0 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TRIM56 | TRIM56 | Q9BRZ2 | E3 ubiquitin-protein ligase TRIM56 | chr7 | Not Cancer Driver | No | 1 | hippie | 110 | 217 | 36 | 36 | 0 |
TUT4_ENST00000371544 | TUT4 | Q5TAX3 | Terminal uridylyltransferase 4 | chr1 | Not Cancer Driver | No | 1 | hippie | 187 | 771 | 102 | 102 | 0 |
UBAP2 | UBAP2 | Q5T6F2 | Ubiquitin-associated protein 2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 1036 | 98 | 98 | 0 |
UBE2E3_ENST00000602710 | UBE2E3 | Q969T4 | Ubiquitin-conjugating enzyme E2 E3 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 34 | 97 | 14 | 14 | 0 |
UBE2H | UBE2H | P62256 | Ubiquitin-conjugating enzyme E2 H | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 55 | 11 | 11 | 0 |
UBR5 | UBR5 | O95071 | E3 ubiquitin-protein ligase UBR5 | chr8 | Census, Compendium | Yes | 1 | hippie | 340 | 1296 | 162 | 162 | 0 |
UNK | UNK | Q9C0B0 | RING finger protein unkempt homolog | chr17 | Not Cancer Driver | No | 1 | hippie | 79 | 511 | 46 | 46 | 0 |
UPF1 | UPF1 | Q92900 | Regulator of nonsense transcripts 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 146 | 329 | 36 | 36 | 0 |
USP10_ENST00000219473 | USP10 | Q14694 | Ubiquitin carboxyl-terminal hydrolase 10 | chr16 | Not Cancer Driver | No | 1 | hippie | 92 | 425 | 49 | 49 | 0 |
VAMP2_ENST00000316509 | VAMP2 | P63027 | Vesicle-associated membrane protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 47 | 4 | 4 | 3 |
VAPA_ENST00000400000 | VAPA | Q9P0L0 | Vesicle-associated membrane protein-associated protein A | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 184 | 14 | 14 | 0 |
VCAM1 | VCAM1 | P19320 | Vascular cell adhesion protein 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 188 | 110 | 28 | 28 | 0 |
VCL | VCL | P18206 | Vinculin | chr10 | Not Cancer Driver | No | 1 | hippie | 114 | 673 | 80 | 80 | 2 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
WDR5 | WDR5 | P61964 | WD repeat-containing protein 5 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 35 | 3 | 3 | 0 |
WWP2 | WWP2 | O00308 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | chr16 | Not Cancer Driver | No | 1 | hippie | 112 | 422 | 57 | 57 | 0 |
XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 140 | 33 | 9 | 9 | 0 |
XRCC1 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 426 | 53 | 53 | 1 |
YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | Not Cancer Driver | No | 1 | hippie | 51 | 489 | 49 | 49 | 0 |
YBX1 | YBX1 | P67809 | Y-box-binding protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 312 | 41 | 41 | 0 |
YEATS2 | YEATS2 | Q9ULM3 | YEATS domain-containing protein 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 170 | 983 | 124 | 124 | 0 |
YTHDF1 | YTHDF1 | Q9BYJ9 | YTH domain-containing family protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 87 | 369 | 46 | 46 | 0 |
YTHDF2_ENST00000542507 | YTHDF2 | Q9Y5A9 | YTH domain-containing family protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 67 | 376 | 44 | 44 | 0 |
YTHDF3_ENST00000539294 | YTHDF3 | Q7Z739 | YTH domain-containing family protein 3 | chr8 | Not Cancer Driver | No | 1 | hippie | 74 | 409 | 51 | 51 | 0 |
ZBTB10 | ZBTB10 | Q96DT7 | Zinc finger and BTB domain-containing protein 10 | chr8 | Not Cancer Driver | No | 1 | hippie | 59 | 531 | 32 | 32 | 0 |
ZC3H7A_ENST00000355758 | ZC3H7A | Q8IWR0 | Zinc finger CCCH domain-containing protein 7A | chr16 | Not Cancer Driver | No | 1 | hippie | 91 | 224 | 23 | 23 | 0 |
ZC3HAV1 | ZC3HAV1 | Q7Z2W4 | Zinc finger CCCH-type antiviral protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 142 | 344 | 63 | 63 | 0 |
ZCCHC14 | ZCCHC14 | Q8WYQ9 | Zinc finger CCHC domain-containing protein 14 | chr16 | Not Cancer Driver | No | 1 | hippie | 121 | 725 | 84 | 84 | 0 |
ZCCHC2 | ZCCHC2 | Q9C0B9 | Zinc finger CCHC domain-containing protein 2 | chr18 | Not Cancer Driver | No | 1 | hippie | 111 | 870 | 86 | 86 | 0 |
ZFP36 | ZFP36 | P26651 | mRNA decay activator protein ZFP36 | chr19 | Not Cancer Driver | No | 1 | hippie | 43 | 262 | 34 | 34 | 0 |
ZP3 | ZP3 | P21754 | Zona pellucida sperm-binding protein 3 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 55 | 56 | 11 | 11 | 1 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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