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TXNDC12 ,TXNDC12 ,O95881
  • Uniprot Accession= O95881
  • Ensembl Transcript= ENST00000371626.8
  • Uniprot Name= TXNDC12
  • Name= Thioredoxin domain-containing protein 12
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 20
  • Number of Interaction partner in biogrid: 70
  • Number of Interaction partner in hippie: 105
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ABHD10 ABHD10 Q9NUJ1 Palmitoyl-protein thioesterase ABHD10, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 38 7 2 2 0
ABHD11 ABHD11 Q8NFV4 Protein ABHD11 chr7 Not Cancer Driver No 1 hippie, biogrid 38 73 6 6 0
ACADSB ACADSB P45954 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 59 16 3 3 1
ACADVL_ENST00000356839 ACADVL P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 50 100 5 5 37
AK2 AK2 P54819 Adenylate kinase 2, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 23 76 12 12 2
AK3 AK3 Q9UIJ7 GTP:AMP phosphotransferase AK3, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 23 33 3 3 0
AK4 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 26 24 3 3 0
ARHGEF1_ENST00000354532 ARHGEF1 Q92888 Rho guanine nucleotide exchange factor 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 127 457 67 67 0
BRAF BRAF P15056 Serine/threonine-protein kinase B-raf chr7 Census, Compendium Yes 1 intact, hippie 791 310 43 43 39
C1orf198 C1orf198 Q9H425 Uncharacterized protein C1orf198 chr1 Not Cancer Driver No 1 hippie, biogrid 40 303 36 36 0
CAMLG CAMLG P49069 Guided entry of tail-anchored proteins factor CAMLG chr5 Not Cancer Driver No 1 intact, hippie 32 157 16 16 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 intact, hippie 30 2 0 0 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 39 23 2 2 1
COA4_ENST00000537289 COA4 Q9NYJ1 Cytochrome c oxidase assembly factor 4 homolog, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 11 85 11 11 0
COMT COMT P21964 Catechol O-methyltransferase chr22 Not Cancer Driver No 1 hippie, biogrid 21 5 0 0 0
COX17_ENST00000497116 COX17 Q14061 Cytochrome c oxidase copper chaperone chr3 Not Cancer Driver No 1 hippie, biogrid 7 15 2 2 0
CTSB CTSB P07858 Cathepsin B chr8 Not Cancer Driver No 2 hippie, biogrid 41 7 2 2 0
CTSL CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie, biogrid 47 34 4 4 0
CTSS CTSS P25774 Cathepsin S chr1 Not Cancer Driver No 1 hippie, biogrid 54 0 0 0 0
CYB5R3_ENST00000352397 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie, biogrid 42 24 3 3 9
CYP51A1 CYP51A1 Q16850 Lanosterol 14-alpha demethylase chr7 Not Cancer Driver No 1 hippie, biogrid 49 7 2 2 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DIAPH2 DIAPH2 O60879 Protein diaphanous homolog 2 chrX Not Cancer Driver No 1 hippie, biogrid 195 460 95 95 0
DPF2_ENST00000528416 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 Not Cancer Driver No 1 intact, hippie 67 179 30 30 5
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie, biogrid 51 21 2 2 0
EPHA10 EPHA10 Q5JZY3 Ephrin type-A receptor 10 chr1 Not Cancer Driver No 1 intact 171 225 41 41 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 Not Cancer Driver No 1 hippie 33 19 0 0 4
FKBP4 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 Not Cancer Driver No 1 hippie, biogrid 46 134 12 12 0
FKBP7 FKBP7 Q9Y680 Peptidyl-prolyl cis-trans isomerase FKBP7 chr2 Not Cancer Driver No 1 intact, hippie 28 52 9 9 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 16 73 0 0 8
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie, biogrid 11 2 1 1 0
GABRQ GABRQ Q9UN88 Gamma-aminobutyric acid receptor subunit theta chrX Not Cancer Driver No 1 intact, hippie 158 175 58 58 0
GIMAP8 GIMAP8 Q8ND71 GTPase IMAP family member 8 chr7 Not Cancer Driver No 1 hippie, biogrid 196 137 34 34 0
GLRX5 GLRX5 Q86SX6 Glutaredoxin-related protein 5, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 7 23 0 0 2
GOT2 GOT2 P00505 Aspartate aminotransferase, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 61 25 3 3 1
GUK1_ENST00000366718 GUK1 Q16774 Guanylate kinase chr1 Not Cancer Driver No 1 hippie, biogrid 28 71 9 9 0
H2AFX H2AX P16104 Histone H2AX chr11 Not Cancer Driver No 1 intact 20 68 10 10 0
HADH_ENST00000309522 HADH Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 33 22 5 5 3
HCCS HCCS P53701 Holocytochrome c-type synthase chrX Not Cancer Driver No 1 hippie, biogrid 48 117 25 25 1
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 Not Cancer Driver No 1 intact, hippie 112 124 25 25 0
HINT1 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 Not Cancer Driver No 1 hippie, biogrid 11 6 0 0 6
HMGCL HMGCL P35914 Hydroxymethylglutaryl-CoA lyase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 17 8 2 2 19
IQGAP2 IQGAP2 Q13576 Ras GTPase-activating-like protein IQGAP2 chr5 Not Cancer Driver No 1 hippie, biogrid 237 255 50 50 0
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KLHL2_ENST00000226725 KLHL2 O95198 Kelch-like protein 2 chr4 Not Cancer Driver No 1 hippie 80 42 5 5 0
LAMTOR2 LAMTOR2 Q9Y2Q5 Ragulator complex protein LAMTOR2 chr1 Not Cancer Driver No 1 hippie, biogrid 12 0 0 0 0
LYPLA1 LYPLA1 O75608 Acyl-protein thioesterase 1 chr8 Not Cancer Driver No 1 hippie, biogrid 19 12 2 2 0
MCF2L2 MCF2L2 Q86YR7 Probable guanine nucleotide exchange factor MCF2L2 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 222 306 61 61 0
MPST_ENST00000341116 MPST P25325 3-mercaptopyruvate sulfurtransferase chr22 Not Cancer Driver No 1 hippie, biogrid 20 72 8 8 0
MSRB2 MSRB2 Q9Y3D2 Methionine-R-sulfoxide reductase B2, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 17 65 6 6 0
MSRB3 MSRB3 Q8IXL7 Methionine-R-sulfoxide reductase B3 chr12 Not Cancer Driver No 1 hippie, biogrid 49 42 14 14 1
MTHFD2 MTHFD2 P13995 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 39 39 3 3 0
MTPN MTPN P58546 Myotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 11 11 3 3 0
MX2 MX2 P20592 Interferon-induced GTP-binding protein Mx2 chr21 Not Cancer Driver No 1 hippie, biogrid 96 159 25 25 0
MZT2A MZT2A Q6P582 Mitotic-spindle organizing protein 2A chr2 Not Cancer Driver No 2 hippie, biogrid 16 114 14 14 0
MZT2B_ENST00000281871 MZT2B Q6NZ67 Mitotic-spindle organizing protein 2B chr2 Not Cancer Driver No 2 intact, hippie, biogrid 14 113 14 14 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NENF NENF Q9UMX5 Neudesin chr1 Not Cancer Driver No 1 hippie, biogrid 15 98 7 7 0
NME7 NME7 Q9Y5B8 Nucleoside diphosphate kinase 7 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 53 0 0 0 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 Not Cancer Driver No 1 hippie, biogrid 207 201 33 33 0
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 29 249 22 22 0
PEBP1 PEBP1 P30086 Phosphatidylethanolamine-binding protein 1 chr12 Not Cancer Driver No 2 hippie, biogrid 23 76 13 13 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie, biogrid 78 58 13 13 0
PMPCA PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 1 hippie, biogrid 67 23 3 3 4
PPA2 PPA2 Q9H2U2 Inorganic pyrophosphatase 2, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 49 71 9 9 9
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 Census Yes 1 hippie 201 189 33 33 2
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
PSAP PSAP P07602 Prosaposin chr10 Not Cancer Driver No 1 hippie, biogrid 59 28 2 2 8
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 Not Cancer Driver No 1 hippie 204 137 34 34 0
RAB11FIP5 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 83 533 70 70 0
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 Not Cancer Driver No 1 hippie, biogrid 16 38 2 2 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 hippie, biogrid 27 11 0 0 4
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
SBF2 SBF2 Q86WG5 Myotubularin-related protein 13 chr11 Not Cancer Driver No 1 hippie 221 367 55 55 0
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 Not Cancer Driver No 1 intact, hippie 38 159 23 23 0
SGTB SGTB Q96EQ0 Small glutamine-rich tetratricopeptide repeat-containing protein beta chr5 Not Cancer Driver No 1 hippie 28 114 10 10 0
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 Not Cancer Driver No 1 intact, hippie 110 440 72 72 0
SRI SRI P30626 Sorcin chr7 Not Cancer Driver No 1 hippie, biogrid 15 32 2 2 0
SUMF2_ENST00000275607 SUMF2 Q8NBJ7-2 Isoform 2 of Inactive C-alpha-formylglycine-generating enzyme 2 chr7 Not Cancer Driver No 1 hippie, biogrid 27 75 12 12 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
TBCA_ENST00000380377 TBCA O75347 Tubulin-specific chaperone A chr5 Not Cancer Driver No 1 hippie, biogrid 8 30 1 1 0
TLN1 TLN1 Q9Y490 Talin-1 chr9 Not Cancer Driver No 1 hippie, biogrid 278 1109 126 126 0
TM2D3 TM2D3 Q9BRN9 TM2 domain-containing protein 3 chr15 Not Cancer Driver No 2 hippie, biogrid 31 13 3 3 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 31 56 4 4 1
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 Not Cancer Driver No 1 hippie, biogrid 9 20 1 1 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TUBG1 TUBG1 P23258 Tubulin gamma-1 chain chr17 Not Cancer Driver No 2 intact, hippie, biogrid 51 44 10 10 3
TUBGCP2_ENST00000368563 TUBGCP2 Q9BSJ2 Gamma-tubulin complex component 2 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 124 93 16 16 0
TUBGCP3 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 2 hippie, biogrid 109 156 16 16 0
TUBGCP4 TUBGCP4 Q9UGJ1 Gamma-tubulin complex component 4 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 79 62 5 5 0
TUBGCP6 TUBGCP6 Q96RT7 Gamma-tubulin complex component 6 chr22 Not Cancer Driver No 2 hippie, biogrid 221 815 105 105 0
TXLNA_ENST00000373610 TXLNA P40222 Alpha-taxilin chr1 Not Cancer Driver No 1 hippie, biogrid 68 481 59 59 0
TXN TXN P10599 Thioredoxin chr9 Not Cancer Driver No 1 hippie, biogrid 6 0 0 0 0
TXNRD2 TXNRD2 Q9NNW7 Thioredoxin reductase 2, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 70 46 6 6 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 64 543 58 58 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 intact, hippie 82 581 79 79 8
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
VBP1 VBP1 P61758 Prefoldin subunit 3 chrX Not Cancer Driver No 1 hippie, biogrid 27 47 7 7 0
YTHDC1_ENST00000344157 YTHDC1 Q96MU7 YTH domain-containing protein 1 chr4 Not Cancer Driver No 1 intact, hippie 137 597 117 117 0
ZDHHC17 ZDHHC17 Q8IUH5 Palmitoyltransferase ZDHHC17 chr12 Not Cancer Driver No 1 hippie 84 49 9 9 0