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TTF2 ,TTF2 ,Q9UNY4
  • Uniprot Accession= Q9UNY4
  • Ensembl Transcript= ENST00000369466.8
  • Uniprot Name= TTF2
  • Name= Transcription termination factor 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 46
  • Number of Interaction partner in biogrid: 61
  • Number of Interaction partner in hippie: 123
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 45 32 1 1 10
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 112 43 5 5 5
AKAP10 AKAP10 O43572 A-kinase anchor protein 10, mitochondrial chr17 Not Cancer Driver No 1 hippie 51 304 16 16 0
AMZ1 AMZ1 Q400G9 Archaemetzincin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 78 147 18 18 0
ASB13 ASB13 Q8WXK3 Ankyrin repeat and SOCS box protein 13 chr10 Not Cancer Driver No 1 hippie, biogrid 35 8 1 1 0
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 Compendium Yes 1 hippie, biogrid 77 53 8 8 6
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 17 112 9 9 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 115 546 73 73 10
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 Census, Compendium Yes 1 hippie 457 1542 225 225 46
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
C12orf74_ENST00000544406 C12orf74 Q6ZR37-3 Isoform 3 of Pleckstrin homology domain-containing family G member 7 chr12 Not Cancer Driver No 1 hippie, biogrid 29 159 26 26 0
CBWD1_ENST00000356521 CBWD1 Q9BRT8 COBW domain-containing protein 1 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 27 62 8 8 0
CCT8L2 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 Not Cancer Driver No 1 hippie, biogrid 216 104 46 46 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 100 618 77 77 0
CDKL3 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 Not Cancer Driver No 1 intact, hippie 68 278 40 40 0
CEP120 CEP120 Q8N960 Centrosomal protein of 120 kDa chr5 Not Cancer Driver No 1 hippie 102 448 52 52 1
CEP128_ENST00000281129 CEP128 Q6ZU80 Centrosomal protein of 128 kDa chr14 Not Cancer Driver No 1 hippie 195 897 167 167 0
CEP152 CEP152 O94986 Centrosomal protein of 152 kDa chr15 Not Cancer Driver No 1 intact, hippie 204 986 110 110 2
CEP162 CEP162 Q5TB80 Centrosomal protein of 162 kDa chr6 Not Cancer Driver No 1 intact, hippie 162 1056 128 128 0
CETN1 CETN1 Q12798 Centrin-1 chr18 Not Cancer Driver No 2 intact, hippie, biogrid 65 105 43 43 0
CETN2 CETN2 P41208 Centrin-2 chrX Not Cancer Driver No 1 intact, hippie 33 97 11 11 0
CIB2 CIB2 O75838 Calcium and integrin-binding family member 2 chr15 Not Cancer Driver No 1 hippie, biogrid 25 7 0 0 5
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CLPB CLPB Q9H078 Caseinolytic peptidase B protein homolog chr11 Not Cancer Driver No 3 intact, hippie, biogrid 69 224 25 25 11
CNTRL_ENST00000238341 CNTRL Q7Z7A1 Centriolin chr9 Census Yes 1 hippie 234 1556 159 159 0
CNTROB_ENST00000563694 CNTROB Q8N137 Centrobin chr17 Not Cancer Driver No 1 intact, hippie 97 837 93 93 0
COMMD1 COMMD1 Q8N668 COMM domain-containing protein 1 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 21 17 0 0 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 Census Yes 1 intact, hippie 25 277 23 23 0
CRYBB3 CRYBB3 P26998 Beta-crystallin B3 chr22 Not Cancer Driver No 1 hippie, biogrid 31 35 6 6 2
D2HGDH D2HGDH Q8N465 D-2-hydroxyglutarate dehydrogenase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 61 46 1 1 0
DCP1A DCP1A Q9NPI6 mRNA-decapping enzyme 1A chr3 Not Cancer Driver No 1 intact, hippie 46 382 31 31 0
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 2 intact, hippie, biogrid 172 817 111 111 11
DKK3_ENST00000326932 DKK3 Q9UBP4 Dickkopf-related protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 44 161 22 22 0
DNAI2 DNAI2 Q9GZS0 Dynein axonemal intermediate chain 2 chr17 Not Cancer Driver No 1 hippie, biogrid 136 209 47 47 0
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 hippie, biogrid 50 174 27 27 0
DR1_ENST00000370267 DR1 Q01658 Protein Dr1 chr1 Not Cancer Driver No 1 hippie 21 84 12 12 0
DRAP1 DRAP1 Q14919 Dr1-associated corepressor chr11 Not Cancer Driver No 1 hippie 28 170 22 22 0
EEF1AKMT3 EEF1AKMT3 Q96AZ1 EEF1A lysine methyltransferase 3 chr12 Not Cancer Driver No 1 hippie 23 33 1 1 0
EMD EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 42 160 28 28 4
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 Not Cancer Driver No 1 hippie, biogrid 125 669 69 69 0
ENTR1 ENTR1 Q96C92 Endosome-associated-trafficking regulator 1 chr9 Not Cancer Driver No 1 hippie 64 267 38 38 0
FAM131B_ENST00000409222 FAM131B Q86XD5 Protein FAM131B chr7 Census Yes 1 intact, hippie, biogrid 78 276 61 61 0
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 71 160 25 25 0
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 Census, Compendium Yes 1 intact, hippie 39 257 20 20 26
FOXN1 FOXN1 O15353 Forkhead box protein N1 chr17 Not Cancer Driver No 1 intact, hippie 90 483 65 65 2
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 Census, Compendium Yes 1 intact, hippie 109 448 71 71 3
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GMEB2_ENST00000370077 GMEB2 Q9UKD1 Glucocorticoid modulatory element-binding protein 2 chr20 Not Cancer Driver No 1 hippie 84 274 39 39 0
GOLGA1 GOLGA1 Q92805 Golgin subfamily A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 99 582 77 77 0
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 69 17 2 2 3
HDAC11 HDAC11 Q96DB2 Histone deacetylase 11 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 57 18 8 8 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 91 570 50 50 0
HINFP HINFP Q9BQA5 Histone H4 transcription factor chr11 Not Cancer Driver No 1 hippie 65 154 24 24 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 intact, hippie 70 290 58 58 4
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 Census, Compendium Yes 1 intact, hippie 68 255 41 41 0
IL17RA IL17RA Q96F46 Interleukin-17 receptor A chr22 Not Cancer Driver No 1 intact, hippie, biogrid 92 301 20 20 0
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 70 6 1 1 0
IQCF1 IQCF1 Q8N6M8 IQ domain-containing protein F1 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 43 70 16 16 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 Not Cancer Driver No 1 hippie 61 277 50 50 0
KIF4A KIF4A O95239 Chromosome-associated kinesin KIF4A chrX Not Cancer Driver No 1 intact, hippie 188 674 116 116 0
KLHL34 KLHL34 Q8N239 Kelch-like protein 34 chrX Not Cancer Driver No 1 hippie, biogrid 103 77 12 12 0
KLK1 KLK1 P06870 Kallikrein-1 chr19 Not Cancer Driver No 1 hippie, biogrid 49 22 3 3 0
LAMTOR5_ENST00000602318 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 Not Cancer Driver No 1 hippie, biogrid 10 17 0 0 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
MAP2K2 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 Census Yes 1 hippie, biogrid 58 105 14 14 4
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 Not Cancer Driver No 1 hippie, biogrid 37 120 16 16 0
MATR3_ENST00000509990 MATR3 P43243 Matrin-3 chr5 Not Cancer Driver No 1 hippie 98 611 68 68 3
MRFAP1L1 MRFAP1L1 Q96HT8 MORF4 family-associated protein 1-like 1 chr4 Not Cancer Driver No 1 hippie, biogrid 12 59 5 5 0
MYBL2 MYBL2 P10244 Myb-related protein B chr20 Not Cancer Driver No 1 hippie 111 506 85 85 0
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 Census Yes 1 hippie 82 528 69 69 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 intact, hippie 104 344 38 38 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 239 1392 164 164 2
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 intact, hippie 230 881 150 150 0
NRBP1_ENST00000379852 NRBP1 Q9UHY1 Nuclear receptor-binding protein chr2 Not Cancer Driver No 1 hippie, biogrid 64 189 29 29 0
NUBP2 NUBP2 Q9Y5Y2 Cytosolic Fe-S cluster assembly factor NUBP2 chr16 Not Cancer Driver No 1 hippie, biogrid 38 14 0 0 0
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 Not Cancer Driver No 1 intact, hippie 90 267 31 31 0
OC90 OC90 Q02509 Otoconin-90 chr8 Not Cancer Driver No 1 hippie, biogrid 131 121 41 41 0
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 Census Yes 1 intact, hippie 152 1665 134 134 0
PDCD6IP_ENST00000307296 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 Not Cancer Driver No 1 intact, hippie 85 272 22 22 0
PEX19 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 41 266 38 38 0
PFN1 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 16 7 1 1 3
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 Not Cancer Driver No 1 hippie, biogrid 72 69 7 7 0
PPM1M_ENST00000323588 PPM1M Q96MI6 Protein phosphatase 1M chr3 Not Cancer Driver No 1 hippie, biogrid 23 87 2 2 0
PPP6R1_ENST00000587283 PPP6R1 Q9UPN7 Serine/threonine-protein phosphatase 6 regulatory subunit 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 82 471 47 47 0
PRDX4 PRDX4 Q13162 Peroxiredoxin-4 chrX Not Cancer Driver No 1 intact, hippie 36 29 2 2 0
PSMC4 PSMC4 P43686 26S proteasome regulatory subunit 6B chr19 Not Cancer Driver No 2 intact, hippie, biogrid 51 21 3 3 0
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 11 52 3 3 0
PUDP_ENST00000381077 PUDP Q08623 Pseudouridine-5'-phosphatase chrX Not Cancer Driver No 1 hippie 45 9 1 1 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 174 291 99 99 0
RAB2B RAB2B Q8WUD1 Ras-related protein Rab-2B chr14 Not Cancer Driver No 1 intact, hippie, biogrid 18 48 4 4 0
RABL2A_ENST00000393166 RABL2A Q9UBK7 Rab-like protein 2A chr2 Not Cancer Driver No 1 hippie, biogrid 23 44 5 5 0
RFXANK_ENST00000407360 RFXANK O14593 DNA-binding protein RFXANK chr19 Not Cancer Driver No 1 hippie, biogrid 22 120 6 6 1
RPGR_ENST00000339363 RPGR Q92834 X-linked retinitis pigmentosa GTPase regulator chrX Not Cancer Driver No 1 intact, hippie 115 639 64 64 25
S100B S100B P04271 Protein S100-B chr21 Not Cancer Driver No 1 hippie, biogrid 17 13 1 1 0
SIRT3 SIRT3 Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 33 60 2 2 0
SKAP1_ENST00000584924 SKAP1 Q86WV1 Src kinase-associated phosphoprotein 1 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 67 130 27 27 0
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 Not Cancer Driver No 1 intact, hippie 77 356 32 32 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 Not Cancer Driver No 1 hippie 54 161 22 22 0
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 Not Cancer Driver No 1 intact, hippie 40 139 0 0 0
SOHLH1_ENST00000298466 SOHLH1 Q5JUK2 Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 48 252 39 39 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie, biogrid 54 267 32 32 30
SRF SRF P11831 Serum response factor chr6 Not Cancer Driver No 1 intact, hippie 44 443 42 42 0
SULT1C4 SULT1C4 O75897 Sulfotransferase 1C4 chr2 Not Cancer Driver No 1 hippie, biogrid 57 19 5 5 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 intact 10 76 7 7 0
TACC3 TACC3 Q9Y6A5 Transforming acidic coiled-coil-containing protein 3 chr4 Not Cancer Driver No 1 hippie 98 707 81 81 0
TCF12_ENST00000267811 TCF12 Q99081 Transcription factor 12 chr15 Census Yes 1 intact, hippie 105 680 105 105 3
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 1 hippie 141 662 136 136 13
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 Compendium Yes 1 hippie 61 285 52 52 0
THTPA THTPA Q9BU02 Thiamine-triphosphatase chr14 Not Cancer Driver No 1 hippie, biogrid 19 56 4 4 0
TJP2_ENST00000377245 TJP2 Q9UDY2 Tight junction protein ZO-2 chr9 Not Cancer Driver No 1 hippie, biogrid 149 919 113 113 1
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 Not Cancer Driver No 2 intact, hippie 85 625 83 83 0
TOP3A TOP3A Q13472 DNA topoisomerase 3-alpha chr17 Not Cancer Driver No 1 hippie, biogrid 103 293 31 31 2
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie, biogrid 40 63 11 11 5
UBD UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 31 8 1 1 0
UBXN6 UBXN6 Q9BZV1 UBX domain-containing protein 6 chr19 Not Cancer Driver No 1 hippie, biogrid 64 132 26 26 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie, biogrid 84 316 57 57 1
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
ZSCAN1 ZSCAN1 Q8NBB4 Zinc finger and SCAN domain-containing protein 1 chr19 Not Cancer Driver No 1 intact, hippie 132 298 98 98 0