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TSPAN2 ,TSPAN2 ,O60636
  • Uniprot Accession= O60636
  • Ensembl Transcript= ENST00000369516.6
  • Uniprot Name= TSPAN2
  • Name= Tetraspanin-2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 40
  • Number of Interaction partner in biogrid: 33
  • Number of Interaction partner in hippie: 77
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 103 47 0 0 0
ABHD16A ABHD16A O95870 Phosphatidylserine lipase ABHD16A chr6 Not Cancer Driver No 1 hippie 69 53 15 15 0
ALG11 ALG11 Q2TAA5 GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase chr13 Not Cancer Driver No 1 hippie, biogrid 46 0 0 0 5
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 18 5 0 0 0
ARL6IP5 ARL6IP5 O75915 PRA1 family protein 3 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 26 0 0 0 0
ATN1_ENST00000396684 ATN1 P54259 Atrophin-1 chr12 Not Cancer Driver No 1 intact 141 1176 139 139 6
ATP1B4 ATP1B4 Q9UN42 Protein ATP1B4 chrX Not Cancer Driver No 1 intact, hippie 85 79 18 18 0
BSCL2_ENST00000421906 BSCL2 Q96G97 Seipin chr11 Not Cancer Driver No 1 hippie, biogrid 55 125 15 15 5
CD151_ENST00000322008 CD151 P48509 CD151 antigen chr11 Not Cancer Driver No 1 hippie, biogrid 26 4 0 0 0
CD63_ENST00000552692 CD63 P08962 CD63 antigen chr12 Not Cancer Driver No 2 hippie, biogrid 27 0 0 0 0
CD79A CD79A P11912 B-cell antigen receptor complex-associated protein alpha chain chr19 Census Yes 1 intact, hippie 32 28 3 3 0
CD9 CD9 P21926 CD9 antigen chr12 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 0
CLDN5_ENST00000618236 CLDN5 O00501 Claudin-5 chr22 Not Cancer Driver No 1 hippie 15 0 0 0 0
CLEC14A CLEC14A Q86T13 C-type lectin domain family 14 member A chr14 Not Cancer Driver No 1 hippie 147 182 60 60 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 Not Cancer Driver No 2 intact, hippie 33 168 11 11 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 Census Yes 1 intact, hippie 68 372 50 50 0
CRYAA CRYAA P02489 Alpha-crystallin A chain chr21 Not Cancer Driver No 1 intact, hippie 34 42 11 11 10
DAGLB DAGLB Q8NCG7 Diacylglycerol lipase-beta chr7 Not Cancer Driver No 2 intact, hippie, biogrid 69 37 3 3 0
DCBLD2 DCBLD2 Q96PD2 Discoidin, CUB and LCCL domain-containing protein 2 chr3 Not Cancer Driver No 1 intact, hippie 108 298 43 43 0
F13A1 F13A1 P00488 Coagulation factor XIII A chain chr6 Not Cancer Driver No 1 intact, hippie 190 84 21 21 17
FAM167A FAM167A Q96KS9 Protein FAM167A chr8 Not Cancer Driver No 1 hippie, biogrid 33 116 17 17 0
FAM209A FAM209A Q5JX71 Protein FAM209A chr20 Not Cancer Driver No 1 intact, hippie 30 53 7 7 0
FAM241A FAM241A Q8N8J7 Uncharacterized protein FAM241A chr4 Not Cancer Driver No 1 intact, hippie 10 67 3 3 0
FAM241B FAM241B Q96D05 Protein FAM241B chr10 Not Cancer Driver No 1 hippie 25 53 9 9 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact, hippie 173 241 26 26 37
FKBP1A FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 Not Cancer Driver No 1 intact 15 39 7 7 0
FKBP7 FKBP7 Q9Y680 Peptidyl-prolyl cis-trans isomerase FKBP7 chr2 Not Cancer Driver No 1 intact, hippie 28 52 9 9 0
FOS FOS P01100 Protein c-Fos chr14 Not Cancer Driver No 1 hippie 45 245 33 33 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
GSN GSN P06396 Gelsolin chr9 Not Cancer Driver No 1 intact, hippie 76 316 28 28 2
HSDL1 HSDL1 Q3SXM5 Inactive hydroxysteroid dehydrogenase-like protein 1 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 24 0 0 0 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 intact, hippie 93 286 38 38 0
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
IFNGR2_ENST00000290219 IFNGR2 P38484 Interferon gamma receptor 2 chr21 Not Cancer Driver No 1 hippie 36 18 2 2 5
KDELR3_ENST00000216014 KDELR3 O43731 ER lumen protein-retaining receptor 3 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 22 0 0 0 0
KDSR KDSR Q06136 3-ketodihydrosphingosine reductase chr18 Census Yes 1 hippie, biogrid 31 35 4 4 1
KLF11 KLF11 O14901 Krueppel-like factor 11 chr2 Not Cancer Driver No 1 hippie 57 308 38 38 2
KLK6 KLK6 Q92876 Kallikrein-6 chr19 Not Cancer Driver No 1 hippie 62 28 12 12 0
LCLAT1 LCLAT1 Q6UWP7 Lysocardiolipin acyltransferase 1 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 59 9 3 3 0
LEPROTL1_ENST00000321250 LEPROTL1 O95214 Leptin receptor overlapping transcript-like 1 chr8 Census Yes 1 hippie 8 0 0 0 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 15 133 6 6 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LPCAT3 LPCAT3 Q6P1A2 Lysophospholipid acyltransferase 5 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 54 1 0 0 0
MFF MFF Q9GZY8 Mitochondrial fission factor chr2 Not Cancer Driver No 1 intact, hippie 59 264 47 47 0
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
MTCH1 MTCH1 Q9NZJ7 Mitochondrial carrier homolog 1 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 31 102 2 2 0
NUP58 NUP58 Q9BVL2 Nucleoporin p58/p45 chr13 Not Cancer Driver No 1 intact, hippie 76 377 49 49 0
PGRMC2_ENST00000296425 PGRMC2 O15173 Membrane-associated progesterone receptor component 2 chr4 Not Cancer Driver No 1 hippie 16 83 4 4 0
PIEZO1 PIEZO1 Q92508 Piezo-type mechanosensitive ion channel component 1 chr16 Not Cancer Driver No 1 hippie, biogrid 122 471 26 26 12
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 Not Cancer Driver No 1 hippie 51 149 20 20 0
PTGFRN PTGFRN Q9P2B2 Prostaglandin F2 receptor negative regulator chr1 Not Cancer Driver No 2 intact, hippie, biogrid 122 121 16 16 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RABGAP1L RABGAP1L Q5R372 Rab GTPase-activating protein 1-like chr1 Not Cancer Driver No 1 hippie 116 235 33 33 0
REEP4 REEP4 Q9H6H4 Receptor expression-enhancing protein 4 chr8 Not Cancer Driver No 1 intact, hippie 27 90 15 15 0
REEP5 REEP5 Q00765 Receptor expression-enhancing protein 5 chr5 Not Cancer Driver No 1 hippie, biogrid 34 0 0 0 0
REEP6 REEP6 Q96HR9-2 Isoform 2 of Receptor expression-enhancing protein 6 chr19 Not Cancer Driver No 2 hippie, biogrid 13 14 1 1 0
RNF19B RNF19B Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B chr1 Not Cancer Driver No 1 hippie 58 344 24 24 0
SCN3B_ENST00000299333 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 Not Cancer Driver No 1 intact, hippie 63 16 5 5 3
SIGMAR1 SIGMAR1 Q99720 Sigma non-opioid intracellular receptor 1 chr9 Not Cancer Driver No 1 hippie, biogrid 22 2 0 0 1
SLC10A6 SLC10A6 Q3KNW5 Solute carrier family 10 member 6 chr4 Not Cancer Driver No 1 hippie 61 38 7 7 0
SLC30A8 SLC30A8 Q8IWU4 Zinc transporter 8 chr8 Not Cancer Driver No 1 intact, hippie 115 25 9 9 0
SLC35C2_ENST00000372227 SLC35C2 Q9NQQ7 Solute carrier family 35 member C2 chr20 Not Cancer Driver No 1 intact, hippie 56 15 2 2 0
SNX13 SNX13 Q9Y5W8 Sorting nexin-13 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 121 132 20 20 0
SNX14 SNX14 Q9Y5W7 Sorting nexin-14 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 94 99 12 12 0
TMED1 TMED1 Q13445 Transmembrane emp24 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 26 26 3 3 0
TMEM130 TMEM130 Q8N3G9 Transmembrane protein 130 chr7 Not Cancer Driver No 1 intact, hippie 78 12 7 7 0
TMEM14B_ENST00000379542 TMEM14B Q9NUH8 Transmembrane protein 14B chr6 Not Cancer Driver No 1 intact, hippie 13 0 0 0 0
TMEM31 TMEM31 Q5JXX7 Transmembrane protein 31 chrX Not Cancer Driver No 1 hippie 26 61 10 10 0
TMX2 TMX2 Q9Y320 Thioredoxin-related transmembrane protein 2 chr11 Not Cancer Driver No 1 hippie 47 40 5 5 3
TPP1 TPP1 O14773 Tripeptidyl-peptidase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 67 92 7 7 37
TSPAN15 TSPAN15 O95858 Tetraspanin-15 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 29 0 0 0 0
TSPAN3 TSPAN3 O60637 Tetraspanin-3 chr15 Not Cancer Driver No 2 hippie, biogrid 23 0 0 0 0
TSPAN31 TSPAN31 Q12999 Tetraspanin-31 chr12 Not Cancer Driver No 1 hippie 22 0 0 0 0
TTYH3 TTYH3 Q9C0H2 Protein tweety homolog 3 chr7 Not Cancer Driver No 1 hippie, biogrid 48 91 14 14 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 64 543 58 58 0
VKORC1L1_ENST00000360768 VKORC1L1 Q8N0U8 Vitamin K epoxide reductase complex subunit 1-like protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 Not Cancer Driver No 1 intact, hippie 52 135 19 19 0
ZDHHC6 ZDHHC6 Q9H6R6 Palmitoyltransferase ZDHHC6 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 43 11 3 3 0
ZFYVE27_ENST00000393677 ZFYVE27 Q5T4F4 Protrudin chr10 Not Cancer Driver No 1 hippie 45 140 22 22 1