Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACTL6A | ACTL6A | O96019 | Actin-like protein 6A | chr3 | Not Cancer Driver | No | 1 | hippie | 61 | 74 | 15 | 15 | 0 |
ACY1 | ACY1 | Q03154 | Aminoacylase-1 | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 49 | 48 | 6 | 6 | 7 |
ANAPC1 | ANAPC1 | Q9H1A4 | Anaphase-promoting complex subunit 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 206 | 263 | 33 | 33 | 0 |
ANAPC4_ENST00000315368 | ANAPC4 | Q9UJX5 | Anaphase-promoting complex subunit 4 | chr4 | Not Cancer Driver | No | 1 | hippie | 70 | 54 | 1 | 1 | 0 |
ANAPC5 | ANAPC5 | Q9UJX4 | Anaphase-promoting complex subunit 5 | chr12 | Not Cancer Driver | No | 1 | hippie | 94 | 41 | 4 | 4 | 0 |
ANAPC7 | ANAPC7 | A0A024RBJ3 | Anaphase promoting complex subunit 7, isoform CRA_b | chr12 | Not Cancer Driver | No | 1 | hippie | 74 | 98 | 17 | 17 | 0 |
ANGEL1 | ANGEL1 | Q9UNK9 | Protein angel homolog 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 85 | 160 | 21 | 21 | 0 |
ANKRD28 | ANKRD28 | O15084 | Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A | chr3 | Not Cancer Driver | No | 1 | hippie | 121 | 115 | 15 | 15 | 0 |
AOX1 | AOX1 | Q06278 | Aldehyde oxidase | chr2 | Not Cancer Driver | No | 1 | hippie | 238 | 70 | 11 | 11 | 0 |
AR | AR | P10275 | Androgen receptor | chrX | Census, Compendium | Yes | 1 | hippie, biogrid | 196 | 443 | 88 | 88 | 169 |
ASF1A | ASF1A | Q9Y294 | Histone chaperone ASF1A | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 69 | 2 | 2 | 0 |
ASS1_ENST00000352480 | ASS1 | P00966 | Argininosuccinate synthase | chr9 | Not Cancer Driver | No | 1 | hippie | 65 | 63 | 8 | 8 | 86 |
BAG2 | BAG2 | O95816 | BAG family molecular chaperone regulator 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 17 | 112 | 9 | 9 | 0 |
BAZ1B_ENST00000404251 | BAZ1B | Q9UIG0 | Tyrosine-protein kinase BAZ1B | chr7 | Not Cancer Driver | No | 1 | hippie | 153 | 840 | 87 | 87 | 0 |
BAZ2A | BAZ2A | Q9UIF9 | Bromodomain adjacent to zinc finger domain protein 2A | chr12 | Not Cancer Driver | No | 1 | hippie | 186 | 1283 | 118 | 118 | 0 |
BCKDHA | BCKDHA | P12694 | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 53 | 121 | 18 | 18 | 11 |
BCKDHB | BCKDHB | P21953 | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie | 47 | 23 | 3 | 3 | 5 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
BRD1_ENST00000216267 | BRD1 | O95696 | Bromodomain-containing protein 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 171 | 425 | 68 | 68 | 0 |
BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
BTBD18 | BTBD18 | B2RXH4 | BTB/POZ domain-containing protein 18 | chr11 | Not Cancer Driver | No | 1 | hippie | 29 | 567 | 25 | 25 | 0 |
BUB1B | BUB1B | O60566 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta | chr15 | Census | Yes | 1 | hippie | 96 | 480 | 35 | 35 | 7 |
C12orf74_ENST00000544406 | C12orf74 | Q6ZR37-3 | Isoform 3 of Pleckstrin homology domain-containing family G member 7 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 159 | 26 | 26 | 0 |
CALM1 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 115 | 15 | 15 | 7 |
CALU_ENST00000249364 | CALU | O43852 | Calumenin | chr7 | Not Cancer Driver | No | 1 | hippie | 34 | 130 | 12 | 12 | 0 |
CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 30 | 2 | 0 | 0 | 0 |
CBFA2T2 | CBFA2T2 | O43439 | Protein CBFA2T2 | chr20 | Not Cancer Driver | No | 1 | hippie | 89 | 457 | 58 | 58 | 0 |
CBFA2T3 | CBFA2T3 | O75081 | Protein CBFA2T3 | chr16 | Census, Compendium | Yes | 1 | hippie | 83 | 502 | 70 | 70 | 0 |
CBX1_ENST00000225603 | CBX1 | P83916 | Chromobox protein homolog 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 31 | 154 | 25 | 25 | 0 |
CBX3_ENST00000396386 | CBX3 | Q13185 | Chromobox protein homolog 3 | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 23 | 119 | 18 | 18 | 0 |
CBX8 | CBX8 | Q9HC52 | Chromobox protein homolog 8 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 309 | 51 | 51 | 0 |
CCNA2_ENST00000618014 | CCNA2 | P20248 | Cyclin-A2 | chr4 | Not Cancer Driver | No | 1 | hippie | 45 | 186 | 19 | 19 | 0 |
CCT8L2 | CCT8L2 | Q96SF2 | T-complex protein 1 subunit theta-like 2 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 216 | 104 | 46 | 46 | 0 |
CDC16_ENST00000356221 | CDC16 | Q13042 | Cell division cycle protein 16 homolog | chr13 | Not Cancer Driver | No | 3 | hippie, biogrid | 68 | 54 | 7 | 7 | 0 |
CDC20 | CDC20 | Q12834 | Cell division cycle protein 20 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 44 | 198 | 15 | 15 | 0 |
CDC23 | CDC23 | Q9UJX2 | Cell division cycle protein 23 homolog | chr5 | Not Cancer Driver | No | 1 | hippie | 57 | 45 | 6 | 6 | 0 |
CDC27_ENST00000066544 | CDC27 | P30260 | Cell division cycle protein 27 homolog | chr17 | Not Cancer Driver | No | 1 | hippie | 179 | 289 | 75 | 75 | 0 |
CDH1 | CDH1 | P12830 | Cadherin-1 | chr16 | Census, Compendium | Yes | 1 | hippie | 150 | 400 | 82 | 82 | 5 |
CDK9 | CDK9 | P50750 | Cyclin-dependent kinase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 50 | 34 | 2 | 2 | 0 |
CEP78_ENST00000424347 | CEP78 | Q5JTW2 | Centrosomal protein of 78 kDa | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 79 | 295 | 32 | 32 | 0 |
CHAMP1 | CHAMP1 | Q96JM3 | Chromosome alignment-maintaining phosphoprotein 1 | chr13 | Not Cancer Driver | No | 1 | hippie | 85 | 624 | 65 | 65 | 0 |
CHD1L | CHD1L | Q86WJ1 | Chromodomain-helicase-DNA-binding protein 1-like | chr1 | Not Cancer Driver | No | 1 | hippie | 98 | 225 | 30 | 30 | 0 |
CHD4 | CHD4 | Q14839 | Chromodomain-helicase-DNA-binding protein 4 | chr12 | Census, Compendium | Yes | 1 | hippie | 419 | 974 | 177 | 177 | 6 |
CHEK1_ENST00000428830 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | Not Cancer Driver | No | 1 | hippie | 58 | 86 | 16 | 16 | 0 |
CNKSR1 | CNKSR1 | Q969H4 | Connector enhancer of kinase suppressor of ras 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 118 | 405 | 68 | 68 | 0 |
COQ8A | COQ8A | Q8NI60 | Atypical kinase COQ8A, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 95 | 166 | 29 | 29 | 12 |
CRYAA | CRYAA | P02489 | Alpha-crystallin A chain | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 42 | 11 | 11 | 10 |
CRYAB_ENST00000616970 | CRYAB | P02511 | Alpha-crystallin B chain | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 59 | 11 | 11 | 4 |
CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | Census, Compendium | Yes | 1 | hippie | 415 | 288 | 301 | 301 | 14 |
CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | Census, Compendium | Yes | 1 | hippie | 123 | 167 | 23 | 23 | 3 |
CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | Census, Compendium | Yes | 1 | hippie | 116 | 213 | 31 | 31 | 3 |
DBT | DBT | P11182 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 64 | 81 | 11 | 11 | 3 |
DCAF15 | DCAF15 | Q66K64 | DDB1- and CUL4-associated factor 15 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 173 | 18 | 18 | 0 |
DCAF7 | DCAF7 | P61962 | DDB1- and CUL4-associated factor 7 | chr17 | Not Cancer Driver | No | 1 | hippie | 48 | 0 | 0 | 0 | 0 |
DGKE | DGKE | P52429 | Diacylglycerol kinase epsilon | chr17 | Not Cancer Driver | No | 1 | hippie | 84 | 34 | 3 | 3 | 2 |
DHX33 | DHX33 | Q9H6R0 | ATP-dependent RNA helicase DHX33 | chr17 | Not Cancer Driver | No | 1 | hippie | 53 | 125 | 12 | 12 | 0 |
DNAJC10 | DNAJC10 | Q8IXB1 | DnaJ homolog subfamily C member 10 | chr2 | Not Cancer Driver | No | 1 | hippie | 110 | 36 | 3 | 3 | 0 |
DPP7 | DPP7 | Q9UHL4 | Dipeptidyl peptidase 2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 29 | 0 | 0 | 0 |
EDEM3 | EDEM3 | Q9BZQ6 | ER degradation-enhancing alpha-mannosidase-like protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 108 | 298 | 38 | 38 | 0 |
ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 69 | 43 | 5 | 5 | 0 |
ELF4 | ELF4 | Q99607 | ETS-related transcription factor Elf-4 | chrX | Census, Compendium | Yes | 1 | hippie | 88 | 486 | 60 | 60 | 0 |
ELF5 | ELF5 | Q9UKW6 | ETS-related transcription factor Elf-5 | chr11 | Not Cancer Driver | No | 1 | hippie | 49 | 0 | 0 | 0 | 0 |
EPAS1 | EPAS1 | Q99814 | Endothelial PAS domain-containing protein 1 | chr2 | Census, Compendium | Yes | 1 | hippie | 120 | 449 | 53 | 53 | 6 |
ERC1 | ERC1 | Q8IUD2 | ELKS/Rab6-interacting/CAST family member 1 | chr12 | Census | Yes | 1 | hippie | 127 | 1013 | 119 | 119 | 0 |
ERG_ENST00000288319 | ERG | P11308 | Transcriptional regulator ERG | chr21 | Census, Compendium | Yes | 1 | hippie | 95 | 296 | 54 | 54 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
EWSR1_ENST00000397938 | EWSR1 | Q01844 | RNA-binding protein EWS | chr22 | Census, Compendium | Yes | 1 | hippie | 94 | 646 | 93 | 93 | 0 |
EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | Census, Compendium | Yes | 1 | hippie | 120 | 284 | 44 | 44 | 11 |
FAM53C_ENST00000434981 | FAM53C | Q9NYF3 | Protein FAM53C | chr5 | Not Cancer Driver | No | 1 | hippie | 51 | 296 | 45 | 45 | 0 |
FBN2_ENST00000262464 | FBN2 | P35556 | Fibrillin-2 | chr5 | Compendium | Yes | 1 | hippie | 607 | 135 | 24 | 24 | 30 |
FGA | FGA | P02671 | Fibrinogen alpha chain | chr4 | Not Cancer Driver | No | 1 | hippie | 245 | 522 | 149 | 149 | 7 |
FHL3 | FHL3 | Q13643 | Four and a half LIM domains protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 0 | 0 | 0 | 0 |
FOS | FOS | P01100 | Protein c-Fos | chr14 | Not Cancer Driver | No | 1 | hippie | 45 | 245 | 33 | 33 | 0 |
FOXA1 | FOXA1 | P55317 | Hepatocyte nuclear factor 3-alpha | chr14 | Census, Compendium | Yes | 1 | hippie | 100 | 295 | 53 | 53 | 0 |
FOXF2 | FOXF2 | Q12947 | Forkhead box protein F2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 277 | 10 | 10 | 0 |
FOXI1 | FOXI1 | Q12951 | Forkhead box protein I1 | chr5 | Not Cancer Driver | No | 1 | hippie | 91 | 253 | 66 | 66 | 0 |
FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 184 | 30 | 30 | 0 |
GCDH_ENST00000591470 | GCDH | Q92947 | Glutaryl-CoA dehydrogenase, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 57 | 37 | 5 | 5 | 58 |
GFOD1 | GFOD1 | Q9NXC2 | Glucose-fructose oxidoreductase domain-containing protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 57 | 35 | 2 | 2 | 0 |
GGCX | GGCX | P38435 | Vitamin K-dependent gamma-carboxylase | chr2 | Not Cancer Driver | No | 1 | hippie | 77 | 131 | 15 | 15 | 8 |
GPX1_ENST00000620890 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 38 | 12 | 1 | 1 | 0 |
HAO2_ENST00000325945 | HAO2 | Q9NYQ3 | 2-Hydroxyacid oxidase 2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 102 | 12 | 5 | 5 | 0 |
HDAC6_ENST00000426196 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | Not Cancer Driver | No | 1 | hippie | 178 | 409 | 59 | 59 | 0 |
HNF4A | HNF4A | P41235 | Hepatocyte nuclear factor 4-alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 135 | 127 | 48 | 48 | 5 |
HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 149 | 251 | 52 | 52 | 0 |
HSPB2 | HSPB2 | Q16082 | Heat shock protein beta-2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 103 | 11 | 11 | 0 |
IMMP1L | IMMP1L | Q96LU5 | Mitochondrial inner membrane protease subunit 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 3 | 0 | 0 | 0 |
JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
KCTD17 | KCTD17 | Q8N5Z5 | BTB/POZ domain-containing protein KCTD17 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 187 | 14 | 14 | 1 |
KDM5C | KDM5C | P41229 | Lysine-specific demethylase 5C | chrX | Census, Compendium | Yes | 1 | hippie | 167 | 499 | 46 | 46 | 10 |
KLF8 | KLF8 | O95600 | Krueppel-like factor 8 | chrX | Not Cancer Driver | No | 1 | hippie | 71 | 270 | 53 | 53 | 0 |
KLHL20 | KLHL20 | Q9Y2M5 | Kelch-like protein 20 | chr1 | Not Cancer Driver | No | 3 | hippie, biogrid | 83 | 143 | 17 | 17 | 0 |
KPNA1 | KPNA1 | P52294 | Importin subunit alpha-5 | chr3 | Not Cancer Driver | No | 1 | hippie | 65 | 121 | 18 | 18 | 0 |
KPNA6 | KPNA6 | O60684 | Importin subunit alpha-7 | chr1 | Not Cancer Driver | No | 1 | hippie | 70 | 97 | 17 | 17 | 0 |
KRT37 | KRT37 | O76014 | Keratin, type I cuticular Ha7 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 105 | 80 | 18 | 18 | 0 |
KRT38 | KRT38 | O76015 | Keratin, type I cuticular Ha8 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 89 | 52 | 15 | 15 | 0 |
KRT39 | KRT39 | Q6A163 | Keratin, type I cytoskeletal 39 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 32 | 2 | 2 | 0 |
LCE3D | LCE3D | Q9BYE3 | Late cornified envelope protein 3D | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 5 | 0 | 0 | 0 |
LDB1 | LDB1 | Q86U70 | LIM domain-binding protein 1 | chr10 | Compendium | Yes | 1 | hippie | 56 | 177 | 29 | 29 | 0 |
LHX4 | LHX4 | Q969G2 | LIM/homeobox protein Lhx4 | chr1 | Not Cancer Driver | No | 1 | hippie | 75 | 219 | 45 | 45 | 4 |
LHX6_ENST00000373755 | LHX6 | Q9UPM6 | LIM/homeobox protein Lhx6 | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 36 | 134 | 10 | 10 | 0 |
LMO2_ENST00000395833 | LMO2 | P25791 | Rhombotin-2 | chr11 | Census | Yes | 2 | hippie, biogrid | 35 | 14 | 1 | 1 | 0 |
LOXL4 | LOXL4 | Q96JB6 | Lysyl oxidase homolog 4 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 122 | 11 | 11 | 0 |
LRP2 | LRP2 | P98164 | Low-density lipoprotein receptor-related protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 998 | 209 | 40 | 40 | 1 |
LYL1 | LYL1 | P12980 | Protein lyl-1 | chr19 | Census | Yes | 1 | hippie | 15 | 243 | 11 | 11 | 0 |
MAD2L1 | MAD2L1 | Q13257 | Mitotic spindle assembly checkpoint protein MAD2A | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 12 | 1 | 1 | 0 |
MAPK6 | MAPK6 | Q16659 | Mitogen-activated protein kinase 6 | chr15 | Not Cancer Driver | No | 1 | hippie | 79 | 165 | 20 | 20 | 0 |
MBD3 | MBD3 | O95983 | Methyl-CpG-binding domain protein 3 | chr19 | Not Cancer Driver | No | 1 | hippie | 50 | 246 | 46 | 46 | 0 |
MDC1 | MDC1 | Q14676 | Mediator of DNA damage checkpoint protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 249 | 1829 | 223 | 223 | 0 |
MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | hippie | 56 | 297 | 37 | 37 | 0 |
MLKL | MLKL | Q8NB16 | Mixed lineage kinase domain-like protein | chr16 | Not Cancer Driver | No | 1 | hippie | 56 | 89 | 15 | 15 | 0 |
MTA1 | MTA1 | Q13330 | Metastasis-associated protein MTA1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 92 | 327 | 42 | 42 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
MYOD1 | MYOD1 | P15172 | Myoblast determination protein 1 | chr11 | Census | Yes | 1 | hippie | 45 | 246 | 33 | 33 | 0 |
NANOG | NANOG | Q9H9S0 | Homeobox protein NANOG | chr12 | Not Cancer Driver | No | 1 | hippie | 46 | 169 | 35 | 35 | 0 |
NCOR1 | NCOR1 | O75376 | Nuclear receptor corepressor 1 | chr17 | Census, Compendium | Yes | 1 | hippie | 352 | 2347 | 340 | 340 | 0 |
NELL2_ENST00000452445 | NELL2 | Q99435 | Protein kinase C-binding protein NELL2 | chr12 | Not Cancer Driver | No | 1 | hippie | 194 | 15 | 4 | 4 | 0 |
NID2 | NID2 | Q14112 | Nidogen-2 | chr14 | Not Cancer Driver | No | 1 | hippie | 270 | 415 | 96 | 96 | 0 |
NIN | NIN | Q8N4C6 | Ninein | chr14 | Census, Compendium | Yes | 1 | hippie | 239 | 1392 | 164 | 164 | 2 |
NLGN3 | NLGN3 | Q9NZ94 | Neuroligin-3 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 158 | 257 | 54 | 54 | 2 |
NT5DC2_ENST00000307076 | NT5DC2 | Q9H857 | 5'-nucleotidase domain-containing protein 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 53 | 21 | 5 | 5 | 0 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
NUP50 | NUP50 | Q9UKX7 | Nuclear pore complex protein Nup50 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 333 | 40 | 40 | 0 |
NUP62 | NUP62 | P37198 | Nuclear pore glycoprotein p62 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 377 | 56 | 56 | 1 |
PBRM1_ENST00000296302 | PBRM1 | Q86U86 | Protein polybromo-1 | chr3 | Census, Compendium | Yes | 1 | hippie | 209 | 703 | 77 | 77 | 0 |
PDIA4 | PDIA4 | P13667 | Protein disulfide-isomerase A4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 147 | 22 | 22 | 0 |
PELO | PELO | Q9BRX2 | Protein pelota homolog | chr5 | Not Cancer Driver | No | 1 | hippie | 38 | 67 | 10 | 10 | 0 |
PER1 | PER1 | O15534 | Period circadian protein homolog 1 | chr17 | Census | Yes | 1 | hippie | 160 | 948 | 116 | 116 | 0 |
PEX5_ENST00000420616 | PEX5 | P50542 | Peroxisomal targeting signal 1 receptor | chr12 | Not Cancer Driver | No | 1 | hippie | 73 | 321 | 36 | 36 | 2 |
PJA2 | PJA2 | O43164 | E3 ubiquitin-protein ligase Praja-2 | chr5 | Not Cancer Driver | No | 1 | hippie | 80 | 598 | 66 | 66 | 0 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
PNMA1 | PNMA1 | Q8ND90 | Paraneoplastic antigen Ma1 | chr14 | Not Cancer Driver | No | 1 | hippie | 48 | 56 | 9 | 9 | 0 |
PNMA2 | PNMA2 | Q9UL42 | Paraneoplastic antigen Ma2 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 45 | 5 | 5 | 0 |
POGZ | POGZ | Q7Z3K3 | Pogo transposable element with ZNF domain | chr1 | Not Cancer Driver | No | 1 | hippie | 157 | 746 | 78 | 78 | 0 |
POLR2C | POLR2C | P19387 | DNA-directed RNA polymerase II subunit RPB3 | chr16 | Not Cancer Driver | No | 1 | hippie | 34 | 108 | 11 | 11 | 0 |
PSME3_ENST00000590720 | PSME3 | P61289 | Proteasome activator complex subunit 3 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 25 | 5 | 5 | 0 |
PTBP3_ENST00000374255 | PTBP3 | O95758 | Polypyrimidine tract-binding protein 3 | chr9 | Not Cancer Driver | No | 1 | hippie | 61 | 114 | 9 | 9 | 0 |
PYCR3_ENST00000495276 | PYCR3 | Q53H96 | Pyrroline-5-carboxylate reductase 3 | chr8 | Not Cancer Driver | No | 1 | hippie | 21 | 11 | 0 | 0 | 0 |
QPRT | QPRT | Q15274 | Nicotinate-nucleotide pyrophosphorylase [carboxylating] | chr16 | Not Cancer Driver | No | 3 | hippie, biogrid | 29 | 7 | 1 | 1 | 0 |
RABGGTB | RABGGTB | P53611 | Geranylgeranyl transferase type-2 subunit beta | chr1 | Not Cancer Driver | No | 3 | hippie, biogrid | 50 | 4 | 1 | 1 | 0 |
RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 34 | 13 | 0 | 0 | 0 |
RB1CC1 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 202 | 578 | 75 | 75 | 0 |
RCN1 | RCN1 | Q15293 | Reticulocalbin-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 35 | 158 | 19 | 19 | 0 |
RCN2_ENST00000394885 | RCN2 | Q14257 | Reticulocalbin-2 | chr15 | Not Cancer Driver | No | 1 | hippie | 35 | 125 | 11 | 11 | 0 |
RESF1 | RESF1 | Q9HCM1 | Retroelement silencing factor 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 217 | 1528 | 185 | 185 | 0 |
RFC4_ENST00000296273 | RFC4 | P35249 | Replication factor C subunit 4 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 50 | 8 | 8 | 0 |
RNF31 | RNF31 | Q96EP0 | E3 ubiquitin-protein ligase RNF31 | chr14 | Not Cancer Driver | No | 1 | hippie | 142 | 319 | 45 | 45 | 0 |
RPS6KA6_ENST00000262752 | RPS6KA6 | Q9UK32 | Ribosomal protein S6 kinase alpha-6 | chrX | Not Cancer Driver | No | 1 | hippie | 180 | 136 | 36 | 36 | 0 |
RRM1 | RRM1 | P23921 | Ribonucleoside-diphosphate reductase large subunit | chr11 | Not Cancer Driver | No | 1 | hippie | 74 | 41 | 7 | 7 | 0 |
RSF1 | RSF1 | Q96T23 | Remodeling and spacing factor 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 153 | 1170 | 130 | 130 | 0 |
RUNX1T1_ENST00000614812 | RUNX1T1 | Q06455 | Protein CBFA2T1 | chr8 | Census, Compendium | Yes | 1 | hippie | 292 | 469 | 229 | 229 | 0 |
RUNX1_ENST00000344691 | RUNX1 | Q01196 | Runt-related transcription factor 1 | chr21 | Census, Compendium | Yes | 1 | hippie | 81 | 360 | 58 | 58 | 2 |
RUVBL1 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 54 | 67 | 7 | 7 | 0 |
SAP30 | SAP30 | O75446 | Histone deacetylase complex subunit SAP30 | chr4 | Not Cancer Driver | No | 1 | hippie | 26 | 123 | 17 | 17 | 0 |
SAT1 | SAT1 | P21673 | Diamine acetyltransferase 1 | chrX | Not Cancer Driver | No | 1 | hippie | 29 | 0 | 0 | 0 | 0 |
SCO2_ENST00000395693 | SCO2 | O43819 | Protein SCO2 homolog, mitochondrial | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 51 | 8 | 8 | 8 |
SDF4 | SDF4 | Q9BRK5 | 45 kDa calcium-binding protein | chr1 | Not Cancer Driver | No | 1 | hippie | 48 | 187 | 30 | 30 | 0 |
SEM1_ENST00000356686 | SEM1 | Q6ZVN7 | Putative protein SEM1, isoform 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 2 | 52 | 1 | 1 | 0 |
SHARPIN | SHARPIN | Q9H0F6 | Sharpin | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 237 | 16 | 16 | 0 |
SKI | SKI | P12755 | Ski oncogene | chr1 | Census | Yes | 1 | hippie | 44 | 432 | 26 | 26 | 14 |
SKIL_ENST00000259119 | SKIL | P12757 | Ski-like protein | chr3 | Not Cancer Driver | No | 1 | hippie | 77 | 356 | 32 | 32 | 0 |
SKIV2L | SKIV2L | Q15477 | Helicase SKI2W | chr6 | Not Cancer Driver | No | 1 | hippie | 140 | 390 | 54 | 54 | 1 |
SLFN11_ENST00000308377 | SLFN11 | Q7Z7L1 | Schlafen family member 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 177 | 34 | 8 | 8 | 0 |
SMAD2_ENST00000402690 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | Census, Compendium | Yes | 1 | hippie | 79 | 137 | 12 | 12 | 0 |
SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | Census, Compendium | Yes | 1 | hippie | 97 | 111 | 19 | 19 | 5 |
SMAD4_ENST00000398417 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | Census, Compendium | Yes | 1 | hippie | 198 | 195 | 17 | 17 | 8 |
SMARCA2 | SMARCA2 | P51531 | Probable global transcription activator SNF2L2 | chr9 | Not Cancer Driver | No | 1 | hippie | 273 | 1009 | 160 | 160 | 42 |
SMARCA4 | SMARCA4 | P51532 | Transcription activator BRG1 | chr19 | Census, Compendium | Yes | 1 | hippie | 349 | 1072 | 195 | 195 | 5 |
SMARCA5 | SMARCA5 | O60264 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 | chr4 | Not Cancer Driver | No | 1 | hippie | 116 | 363 | 48 | 48 | 0 |
SMARCE1 | SMARCE1 | Q969G3 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 | chr17 | Census | Yes | 1 | hippie | 47 | 332 | 36 | 36 | 2 |
SOD1 | SOD1 | P00441 | Superoxide dismutase [Cu-Zn] | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 93 | 9 | 9 | 79 |
SOHLH1_ENST00000298466 | SOHLH1 | Q5JUK2 | Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 252 | 39 | 39 | 0 |
SOX17 | SOX17 | Q9H6I2 | Transcription factor SOX-17 | chr8 | Compendium | Yes | 1 | hippie | 81 | 378 | 59 | 59 | 2 |
SOX2 | SOX2 | P48431 | Transcription factor SOX-2 | chr3 | Census | Yes | 1 | hippie | 39 | 312 | 39 | 39 | 0 |
SOX7 | SOX7 | Q9BT81 | Transcription factor SOX-7 | chr8 | Not Cancer Driver | No | 1 | hippie | 92 | 353 | 91 | 91 | 0 |
SP100_ENST00000264052 | SP100 | P23497 | Nuclear autoantigen Sp-100 | chr2 | Not Cancer Driver | No | 1 | hippie | 136 | 680 | 101 | 101 | 0 |
SP7 | SP7 | Q8TDD2 | Transcription factor Sp7 | chr12 | Not Cancer Driver | No | 1 | hippie | 63 | 332 | 44 | 44 | 0 |
SSB | SSB | P05455 | Lupus La protein | chr2 | Not Cancer Driver | No | 1 | hippie | 39 | 181 | 18 | 18 | 0 |
SSBP2_ENST00000320672 | SSBP2 | P81877 | Single-stranded DNA-binding protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 36 | 296 | 29 | 29 | 0 |
SSBP3 | SSBP3 | Q9BWW4 | Single-stranded DNA-binding protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 321 | 42 | 42 | 0 |
SSBP4 | SSBP4 | Q9BWG4 | Single-stranded DNA-binding protein 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 32 | 316 | 21 | 21 | 0 |
SSRP1 | SSRP1 | Q08945 | FACT complex subunit SSRP1 | chr11 | Not Cancer Driver | No | 1 | hippie | 92 | 308 | 35 | 35 | 0 |
SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 10 | 76 | 7 | 7 | 0 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 9 | 69 | 6 | 6 | 0 |
SUMO3_ENST00000332859 | SUMO3 | P55854 | Small ubiquitin-related modifier 3 | chr21 | Not Cancer Driver | No | 1 | hippie | 7 | 87 | 5 | 5 | 0 |
SUPT16H | SUPT16H | Q9Y5B9 | FACT complex subunit SPT16 | chr14 | Not Cancer Driver | No | 1 | hippie | 147 | 301 | 44 | 44 | 0 |
TAL1 | TAL1 | P17542 | T-cell acute lymphocytic leukemia protein 1 | chr1 | Census | Yes | 1 | hippie | 54 | 305 | 53 | 53 | 0 |
TCF12_ENST00000267811 | TCF12 | Q99081 | Transcription factor 12 | chr15 | Census | Yes | 1 | hippie | 105 | 680 | 105 | 105 | 3 |
TCF3 | TCF3 | P15923 | Transcription factor E2-alpha | chr19 | Census | Yes | 1 | hippie | 52 | 649 | 52 | 52 | 0 |
TCF4_ENST00000564999 | TCF4 | P15884 | Transcription factor 4 | chr18 | Compendium | Yes | 1 | hippie | 141 | 662 | 136 | 136 | 13 |
TDP1_ENST00000393454 | TDP1 | Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 81 | 179 | 25 | 25 | 1 |
TERF2IP | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 310 | 16 | 16 | 0 |
TGM7 | TGM7 | Q96PF1 | Protein-glutamine gamma-glutamyltransferase Z | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 119 | 80 | 8 | 8 | 0 |
THOC1 | THOC1 | Q96FV9 | THO complex subunit 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 55 | 280 | 26 | 26 | 0 |
THRSP | THRSP | Q92748 | Thyroid hormone-inducible hepatic protein | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 47 | 7 | 7 | 0 |
TIMM50_ENST00000607714 | TIMM50 | Q3ZCQ8 | Mitochondrial import inner membrane translocase subunit TIM50 | chr19 | Not Cancer Driver | No | 1 | hippie | 39 | 75 | 7 | 7 | 0 |
TMX3 | TMX3 | Q96JJ7 | Protein disulfide-isomerase TMX3 | chr18 | Not Cancer Driver | No | 1 | hippie | 50 | 49 | 9 | 9 | 0 |
TP53BP1_ENST00000263801 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 227 | 1632 | 190 | 190 | 0 |
TPM3 | TPM3 | P06753 | Tropomyosin alpha-3 chain | chr1 | Census | Yes | 1 | hippie, biogrid | 35 | 230 | 27 | 27 | 21 |
TRAF2 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | Not Cancer Driver | No | 1 | hippie | 63 | 4 | 1 | 1 | 0 |
TRIM24 | TRIM24 | O15164 | Transcription intermediary factor 1-alpha | chr7 | Census, Compendium | Yes | 2 | hippie, biogrid | 120 | 537 | 61 | 61 | 0 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 87 | 430 | 41 | 41 | 0 |
TRIM33 | TRIM33 | Q9UPN9 | E3 ubiquitin-protein ligase TRIM33 | chr1 | Census, Compendium | Yes | 1 | hippie | 110 | 617 | 51 | 51 | 0 |
TRIM37 | TRIM37 | O94972 | E3 ubiquitin-protein ligase TRIM37 | chr17 | Not Cancer Driver | No | 1 | hippie | 119 | 492 | 60 | 60 | 3 |
TRIM4 | TRIM4 | Q9C037 | E3 ubiquitin-protein ligase TRIM4 | chr7 | Not Cancer Driver | No | 1 | hippie | 51 | 40 | 5 | 5 | 0 |
TRIM52 | TRIM52 | Q96A61 | E3 ubiquitin-protein ligase TRIM52 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 147 | 13 | 13 | 0 |
TTC37 | TTC37 | Q6PGP7 | Tetratricopeptide repeat protein 37 | chr5 | Not Cancer Driver | No | 1 | hippie | 164 | 59 | 3 | 3 | 3 |
TUBG1 | TUBG1 | P23258 | Tubulin gamma-1 chain | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 44 | 10 | 10 | 3 |
UACA | UACA | Q9BZF9 | Uveal autoantigen with coiled-coil domains and ankyrin repeats | chr15 | Not Cancer Driver | No | 1 | hippie | 177 | 863 | 101 | 101 | 0 |
UBE2D2 | UBE2D2 | P62837 | Ubiquitin-conjugating enzyme E2 D2 | chr5 | Compendium | Yes | 1 | hippie | 19 | 13 | 1 | 1 | 0 |
UBE2D3_ENST00000394801 | UBE2D3 | P61077 | Ubiquitin-conjugating enzyme E2 D3 | chr4 | Not Cancer Driver | No | 1 | hippie | 21 | 13 | 4 | 4 | 0 |
UBE2E1 | UBE2E1 | P51965 | Ubiquitin-conjugating enzyme E2 E1 | chr3 | Not Cancer Driver | No | 1 | hippie | 21 | 78 | 10 | 10 | 0 |
UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 1 | hippie | 16 | 16 | 3 | 3 | 0 |
UBE2N | UBE2N | P61088 | Ubiquitin-conjugating enzyme E2 N | chr12 | Not Cancer Driver | No | 1 | hippie | 25 | 24 | 3 | 3 | 0 |
UNC80 | UNC80 | Q8N2C7 | Protein unc-80 homolog | chr2 | Not Cancer Driver | No | 1 | hippie | 290 | 1236 | 131 | 131 | 2 |
VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 186 | 16 | 16 | 16 |
VDAC2_ENST00000543351 | VDAC2 | P45880 | Voltage-dependent anion-selective channel protein 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 35 | 9 | 1 | 1 | 0 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 140 | 33 | 9 | 9 | 0 |
YAF2_ENST00000534854 | YAF2 | Q8IY57 | YY1-associated factor 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 27 | 166 | 27 | 27 | 0 |
YEATS4 | YEATS4 | O95619 | YEATS domain-containing protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie | 23 | 17 | 1 | 1 | 0 |
ZBTB1 | ZBTB1 | Q9Y2K1 | Zinc finger and BTB domain-containing protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 70 | 271 | 27 | 27 | 0 |
ZFP82 | ZFP82 | Q8N141 | Zinc finger protein 82 homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 92 | 50 | 7 | 7 | 0 |
ZIM2_ENST00000601070 | ZIM2 | Q9NZV7 | Zinc finger imprinted 2 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 174 | 281 | 96 | 96 | 0 |
ZNF324B | ZNF324B | Q6AW86 | Zinc finger protein 324B | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 87 | 266 | 40 | 40 | 0 |
ZNF333 | ZNF333 | Q96JL9 | Zinc finger protein 333 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 79 | 271 | 32 | 32 | 0 |
ZNF418_ENST00000396147 | ZNF418 | Q8TF45 | Zinc finger protein 418 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 133 | 172 | 44 | 44 | 0 |
ZNF43_ENST00000354959 | ZNF43 | P17038 | Zinc finger protein 43 | chr19 | Not Cancer Driver | No | 1 | hippie | 172 | 63 | 8 | 8 | 0 |
ZNF44 | ZNF44 | P15621 | Zinc finger protein 44 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 90 | 12 | 12 | 0 |
ZNF460 | ZNF460 | Q14592 | Zinc finger protein 460 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 131 | 16 | 16 | 0 |
ZNF484_ENST00000375495 | ZNF484 | Q5JVG2 | Zinc finger protein 484 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 101 | 150 | 12 | 12 | 0 |
ZNF747 | ZNF747 | Q9BV97 | Zinc finger protein 747 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 192 | 15 | 15 | 0 |
ZNF764 | ZNF764 | Q96H86 | Zinc finger protein 764 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 225 | 30 | 30 | 0 |
ZNF776 | ZNF776 | Q68DI1 | Zinc finger protein 776 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 147 | 23 | 23 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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