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TRAF5_ENST00000336184 ,TRAF5 ,O00463
  • Uniprot Accession= O00463
  • Ensembl Transcript= ENST00000336184.6
  • Uniprot Name= TRAF5
  • Name= TNF receptor-associated factor 5
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 7
  • Number of Interaction partner in hippie: 91
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AHCYL1 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 58 108 10 10 0
BEX3_ENST00000372635 BEX3 Q00994 Protein BEX3 chrX Not Cancer Driver No 1 hippie 19 98 17 17 0
CAMLG CAMLG P49069 Guided entry of tail-anchored proteins factor CAMLG chr5 Not Cancer Driver No 1 hippie 32 157 16 16 0
CAPNS1 CAPNS1 P04632 Calpain small subunit 1 chr19 Not Cancer Driver No 1 hippie 30 58 5 5 0
CCDC184 CCDC184 Q52MB2 Coiled-coil domain-containing protein 184 chr12 Not Cancer Driver No 1 hippie 22 183 22 22 0
CCDC40 CCDC40 Q4G0X9 Coiled-coil domain-containing protein 40 chr17 Not Cancer Driver No 2 hippie, biogrid 201 672 123 123 0
CD27 CD27 P26842 CD27 antigen chr12 Not Cancer Driver No 1 hippie 30 92 11 11 1
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 Not Cancer Driver No 1 hippie 39 56 6 6 2
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 hippie 52 214 31 31 0
CDC40 CDC40 O60508 Pre-mRNA-processing factor 17 chr6 Not Cancer Driver No 1 hippie 79 214 27 27 1
CIB3 CIB3 Q96Q77 Calcium and integrin-binding family member 3 chr19 Not Cancer Driver No 1 hippie 55 3 2 2 0
COG5_ENST00000347053 COG5 Q9UP83 Conserved oligomeric Golgi complex subunit 5 chr7 Not Cancer Driver No 1 hippie 101 118 23 23 0
COG7 COG7 P83436 Conserved oligomeric Golgi complex subunit 7 chr16 Not Cancer Driver No 2 hippie, biogrid 85 60 6 6 0
DGKH DGKH Q86XP1 Diacylglycerol kinase eta chr13 Not Cancer Driver No 1 hippie 138 326 43 43 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 Not Cancer Driver No 1 hippie 62 84 8 8 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 Not Cancer Driver No 1 hippie 59 188 22 22 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ENOX2 ENOX2 Q16206 Ecto-NOX disulfide-thiol exchanger 2 chrX Not Cancer Driver No 1 hippie 103 239 41 41 0
FAM9A_ENST00000381003 FAM9A Q8IZU1 Protein FAM9A chrX Not Cancer Driver No 1 hippie 77 332 77 77 0
FBXO28 FBXO28 Q9NVF7 F-box only protein 28 chr1 Not Cancer Driver No 2 hippie, biogrid 49 230 30 30 0
GAS8 GAS8 O95995 Dynein regulatory complex subunit 4 chr16 Not Cancer Driver No 1 hippie 54 232 29 29 1
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 hippie 115 854 96 96 0
GORASP2 GORASP2 Q9H8Y8 Golgi reassembly-stacking protein 2 chr2 Not Cancer Driver No 1 hippie 55 287 31 31 0
HOMER1 HOMER1 Q86YM7 Homer protein homolog 1 chr5 Not Cancer Driver No 3 hippie, biogrid 46 243 32 32 0
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX Not Cancer Driver No 1 hippie 27 15 3 3 11
HSF2BP HSF2BP O75031 Heat shock factor 2-binding protein chr21 Not Cancer Driver No 1 hippie 52 23 3 3 1
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie 43 55 7 7 1
LMO4 LMO4 P61968 LIM domain transcription factor LMO4 chr1 Not Cancer Driver No 1 hippie 30 11 1 1 0
LNX1 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 1 hippie 117 261 40 40 0
LTBR LTBR P36941 Tumor necrosis factor receptor superfamily member 3 chr12 Not Cancer Driver No 1 hippie 44 200 21 21 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie, biogrid 78 508 66 66 0
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 1 hippie 94 543 52 52 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 Not Cancer Driver No 1 hippie 197 242 29 29 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 hippie 104 333 66 66 6
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 Not Cancer Driver No 1 hippie 70 411 58 58 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MEOX2 MEOX2 P50222 Homeobox protein MOX-2 chr7 Not Cancer Driver No 1 hippie 70 274 63 63 0
NFATC2IP NFATC2IP Q8NCF5 NFATC2-interacting protein chr16 Not Cancer Driver No 1 hippie 41 330 29 29 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 Not Cancer Driver No 1 hippie 57 172 25 25 0
NMI NMI Q13287 N-myc-interactor chr2 Not Cancer Driver No 1 hippie 34 104 12 12 0
NUMBL NUMBL Q9Y6R0 Numb-like protein chr19 Not Cancer Driver No 1 hippie 42 467 23 23 0
ODF2 ODF2 Q5BJF6 Outer dense fiber protein 2 chr9 Not Cancer Driver No 1 hippie 123 607 90 90 0
PHYH PHYH O14832 Phytanoyl-CoA dioxygenase, peroxisomal chr10 Not Cancer Driver No 1 hippie 54 40 4 4 14
PIAS2 PIAS2 O75928 E3 SUMO-protein ligase PIAS2 chr18 Not Cancer Driver No 1 hippie 78 209 28 28 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 Not Cancer Driver No 1 hippie 83 419 45 45 2
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 Not Cancer Driver No 1 hippie 50 49 3 3 0
PSMA1_ENST00000396394 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 Not Cancer Driver No 1 hippie 48 51 9 9 0
RAD23A RAD23A P54725 UV excision repair protein RAD23 homolog A chr19 Not Cancer Driver No 1 hippie 50 283 41 41 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 Compendium Yes 1 hippie 82 277 39 39 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 Not Cancer Driver No 1 hippie 63 143 20 20 0
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 Not Cancer Driver No 1 hippie 111 855 96 96 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 Not Cancer Driver No 1 hippie 96 187 36 36 1
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 Not Cancer Driver No 1 hippie 39 17 2 2 0
SEC13_ENST00000350697 SEC13 P55735 Protein SEC13 homolog chr3 Not Cancer Driver No 1 hippie 34 36 6 6 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 Not Cancer Driver No 1 hippie 64 22 2 2 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 hippie 71 194 35 35 2
SRSF1 SRSF1 Q07955 Serine/arginine-rich splicing factor 1 chr17 Not Cancer Driver No 1 hippie 41 198 34 34 0
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie 74 270 39 39 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 2 hippie, biogrid 42 302 26 26 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 1 hippie 101 42 5 5 12
TDP2 TDP2 O95551 Tyrosyl-DNA phosphodiesterase 2 chr6 Not Cancer Driver No 1 hippie 55 80 10 10 0
THAP1 THAP1 Q9NVV9 THAP domain-containing protein 1 chr8 Not Cancer Driver No 1 hippie 19 76 8 8 45
THAP7_ENST00000399133 THAP7 Q9BT49 THAP domain-containing protein 7 chr22 Not Cancer Driver No 1 hippie 34 214 24 24 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 Not Cancer Driver No 1 hippie 92 443 66 66 1
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 Not Cancer Driver No 1 hippie 70 285 33 33 0
TNFRSF12A TNFRSF12A Q9NP84 Tumor necrosis factor receptor superfamily member 12A chr16 Not Cancer Driver No 1 hippie 8 0 0 0 0
TNFRSF13B TNFRSF13B O14836 Tumor necrosis factor receptor superfamily member 13B chr17 Not Cancer Driver No 1 hippie 60 108 25 25 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 Census, Compendium Yes 1 hippie 33 54 8 8 0
TNFRSF17 TNFRSF17 Q02223 Tumor necrosis factor receptor superfamily member 17 chr16 Census Yes 1 hippie 28 1 0 0 0
TNFRSF19 TNFRSF19 Q9NS68 Tumor necrosis factor receptor superfamily member 19 chr13 Not Cancer Driver No 1 hippie 72 103 19 19 0
TNFRSF4 TNFRSF4 P43489 Tumor necrosis factor receptor superfamily member 4 chr1 Not Cancer Driver No 1 hippie 30 94 14 14 1
TNFRSF8 TNFRSF8 P28908 Tumor necrosis factor receptor superfamily member 8 chr1 Not Cancer Driver No 1 hippie 95 286 35 35 0
TNFRSF9 TNFRSF9 Q07011 Tumor necrosis factor receptor superfamily member 9 chr1 Not Cancer Driver No 1 hippie 43 29 10 10 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 1 hippie 63 4 1 1 0
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 Not Cancer Driver No 1 hippie 59 410 39 39 2
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 Compendium Yes 1 hippie 61 101 9 9 1
TRAF5_ENST00000336184 TRAF5 O00463 TNF receptor-associated factor 5 chr1 Not Cancer Driver No 1 hippie 61 59 5 5 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 67 62 7 7 0
TRAIP TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 Not Cancer Driver No 1 hippie 63 240 33 33 1
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 hippie 59 87 11 11 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
TRIM8 TRIM8 Q9BZR9 E3 ubiquitin-protein ligase TRIM8 chr10 Not Cancer Driver No 1 hippie 60 209 29 29 0
UBE2O UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 Not Cancer Driver No 1 hippie 129 716 68 68 0
USP25_ENST00000285679 USP25 Q9UHP3 Ubiquitin carboxyl-terminal hydrolase 25 chr21 Not Cancer Driver No 1 hippie 135 354 55 55 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 1 hippie 170 215 45 45 0
YPEL5 YPEL5 P62699 Protein yippee-like 5 chr2 Not Cancer Driver No 1 hippie 19 10 3 3 0
ZFAND6 ZFAND6 Q6FIF0 AN1-type zinc finger protein 6 chr15 Not Cancer Driver No 1 hippie 26 140 17 17 0
ZMYND11 ZMYND11 Q15326 Zinc finger MYND domain-containing protein 11 chr10 Not Cancer Driver No 1 hippie 71 184 26 26 0
ZNF655_ENST00000252713 ZNF655 Q8N720 Zinc finger protein 655 chr7 Not Cancer Driver No 1 hippie 62 202 27 27 0