Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AAR2_ENST00000320849 | AAR2 | Q9Y312 | Protein AAR2 homolog | chr20 | Not Cancer Driver | No | 2 | hippie, biogrid | 56 | 28 | 6 | 6 | 0 |
ACTA1 | ACTA1 | P68133 | Actin, alpha skeletal muscle | chr1 | Not Cancer Driver | No | 1 | hippie | 70 | 48 | 14 | 14 | 84 |
ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 112 | 43 | 5 | 5 | 5 |
ACTN1_ENST00000193403 | ACTN1 | P12814 | Alpha-actinin-1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 195 | 30 | 30 | 6 |
ACTN2_ENST00000366578 | ACTN2 | P35609 | Alpha-actinin-2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 227 | 131 | 29 | 29 | 9 |
ACTN4 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 131 | 244 | 42 | 42 | 8 |
ADD1_ENST00000398129 | ADD1 | P35611 | Alpha-adducin | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 106 | 439 | 64 | 64 | 0 |
AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 20 | 2 | 2 | 0 |
AGRN | AGRN | O00468 | Agrin | chr1 | Not Cancer Driver | No | 1 | hippie | 188 | 490 | 40 | 40 | 5 |
AHCYL1 | AHCYL1 | O43865 | S-adenosylhomocysteine hydrolase-like protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 108 | 10 | 10 | 0 |
ANLN | ANLN | Q9NQW6 | Anillin | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 144 | 767 | 104 | 104 | 2 |
ANTXR1 | ANTXR1 | Q9H6X2 | Anthrax toxin receptor 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 105 | 183 | 44 | 44 | 0 |
APBB1 | APBB1 | O00213 | Amyloid beta precursor protein binding family B member 1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 105 | 399 | 58 | 58 | 0 |
APOE | APOE | P02649 | Apolipoprotein E | chr19 | Not Cancer Driver | No | 1 | hippie | 25 | 124 | 6 | 6 | 12 |
AR | AR | P10275 | Androgen receptor | chrX | Census, Compendium | Yes | 1 | hippie | 196 | 443 | 88 | 88 | 169 |
ARHGAP11A | ARHGAP11A | Q6P4F7 | Rho GTPase-activating protein 11A | chr15 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 127 | 696 | 93 | 93 | 0 |
ARHGAP39_ENST00000276826 | ARHGAP39 | Q9C0H5 | Rho GTPase-activating protein 39 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 120 | 613 | 61 | 61 | 0 |
ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 65 | 451 | 58 | 58 | 0 |
ATN1_ENST00000396684 | ATN1 | P54259 | Atrophin-1 | chr12 | Not Cancer Driver | No | 1 | intact | 141 | 1176 | 139 | 139 | 6 |
ATP1A1_ENST00000295598 | ATP1A1 | P05023 | Sodium/potassium-transporting ATPase subunit alpha-1 | chr1 | Census | Yes | 1 | hippie, biogrid | 115 | 115 | 16 | 16 | 6 |
ATP5PB | ATP5PB | P24539 | ATP synthase F(0) complex subunit B1, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 37 | 2 | 0 | 0 | 0 |
ATXN1 | ATXN1 | P54253 | Ataxin-1 | chr6 | Not Cancer Driver | No | 2 | intact, hippie | 193 | 604 | 168 | 168 | 0 |
AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 63 | 8 | 8 | 0 |
BACE2 | BACE2 | Q9Y5Z0 | Beta-secretase 2 | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 61 | 23 | 2 | 2 | 0 |
BCAR1_ENST00000162330 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 108 | 677 | 75 | 75 | 0 |
BCAR3_ENST00000260502 | BCAR3 | O75815 | Breast cancer anti-estrogen resistance protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 102 | 395 | 42 | 42 | 0 |
BCKDK | BCKDK | O14874 | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 39 | 3 | 3 | 3 |
BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
BLOC1S6_ENST00000220531 | BLOC1S6 | Q9UL45 | Biogenesis of lysosome-related organelles complex 1 subunit 6 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 12 | 111 | 11 | 11 | 0 |
BMI1 | BMI1 | P35226 | Polycomb complex protein BMI-1 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 150 | 30 | 30 | 0 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
BTF3 | BTF3 | P20290 | Transcription factor BTF3 | chr5 | Not Cancer Driver | No | 1 | hippie | 27 | 192 | 24 | 24 | 0 |
C1orf216 | C1orf216 | Q8TAB5 | UPF0500 protein C1orf216 | chr1 | Not Cancer Driver | No | 3 | intact, hippie | 22 | 199 | 21 | 21 | 0 |
CALCOCO1 | CALCOCO1 | Q9P1Z2 | Calcium-binding and coiled-coil domain-containing protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 88 | 486 | 59 | 59 | 0 |
CALM1 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 115 | 15 | 15 | 7 |
CALR | CALR | P27797 | Calreticulin | chr19 | Census | Yes | 1 | hippie, biogrid | 45 | 245 | 31 | 31 | 0 |
CAP1_ENST00000372805 | CAP1 | Q01518 | Adenylyl cyclase-associated protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 70 | 156 | 31 | 31 | 0 |
CAPZA2 | CAPZA2 | P47755 | F-actin-capping protein subunit alpha-2 | chr7 | Not Cancer Driver | No | 1 | hippie | 37 | 19 | 0 | 0 | 0 |
CAVIN1 | CAVIN1 | Q6NZI2 | Caveolae-associated protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 66 | 280 | 50 | 50 | 0 |
CAVIN3 | CAVIN3 | Q969G5 | Caveolae-associated protein 3 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 22 | 234 | 19 | 19 | 0 |
CCDC102A | CCDC102A | Q96A19 | Coiled-coil domain-containing protein 102A | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 526 | 43 | 43 | 0 |
CCDC102B | CCDC102B | Q68D86 | Coiled-coil domain-containing protein 102B | chr18 | Not Cancer Driver | No | 1 | hippie | 133 | 334 | 89 | 89 | 0 |
CCDC114 | ODAD1 | Q96M63 | Outer dynein arm-docking complex subunit 1 | chr19 | Not Cancer Driver | No | 1 | intact | 90 | 332 | 52 | 52 | 0 |
CCDC146 | CCDC146 | Q8IYE0 | Coiled-coil domain-containing protein 146 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 124 | 288 | 38 | 38 | 0 |
CCDC6 | CCDC6 | Q16204 | Coiled-coil domain-containing protein 6 | chr10 | Census, Compendium | Yes | 1 | hippie, biogrid | 59 | 373 | 52 | 52 | 0 |
CCDC96 | CCDC96 | Q2M329 | Coiled-coil domain-containing protein 96 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 308 | 41 | 41 | 0 |
CCHCR1_ENST00000376266 | CCHCR1 | Q8TD31 | Coiled-coil alpha-helical rod protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 116 | 565 | 88 | 88 | 0 |
CCNF | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 221 | 23 | 23 | 3 |
CD274 | CD274 | Q9NZQ7 | Programmed cell death 1 ligand 1 | chr9 | Census | Yes | 1 | hippie | 29 | 54 | 9 | 9 | 0 |
CDC123 | CDC123 | O75794 | Cell division cycle protein 123 homolog | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 57 | 4 | 4 | 0 |
CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 2 | intact, hippie | 24 | 0 | 0 | 0 | 0 |
CDK9 | CDK9 | P50750 | Cyclin-dependent kinase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 50 | 34 | 2 | 2 | 0 |
CEP78_ENST00000424347 | CEP78 | Q5JTW2 | Centrosomal protein of 78 kDa | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 79 | 295 | 32 | 32 | 0 |
CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 2 | intact, hippie | 287 | 145 | 18 | 18 | 151 |
CHRM3_ENST00000615928 | CHRM3 | P20309 | Muscarinic acetylcholine receptor M3 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 182 | 136 | 42 | 42 | 0 |
CHUK | CHUK | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 74 | 116 | 9 | 9 | 0 |
CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
CKB | CKB | P12277 | Creatine kinase B-type | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 102 | 4 | 4 | 0 |
CKMT1A_ENST00000626814 | CKMT1A | F8WCN3 | Creatine kinase | chr15 | Not Cancer Driver | No | 1 | biogrid | 5 | 70 | 1 | 1 | 0 |
CKMT1B_ENST00000441322 | CKMT1B | P12532 | Creatine kinase U-type, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 77 | 1 | 1 | 0 |
CNN1 | CNN1 | P51911 | Calponin-1 | chr19 | Not Cancer Driver | No | 1 | hippie | 56 | 200 | 39 | 39 | 0 |
COQ2_ENST00000647002 | COQ2 | Q96H96 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial | chr4 | Not Cancer Driver | No | 1 | intact | 23 | 25 | 0 | 0 | 17 |
COX15 | COX15 | Q7KZN9 | Cytochrome c oxidase assembly protein COX15 homolog | chr10 | Not Cancer Driver | No | 1 | intact | 48 | 0 | 0 | 0 | 2 |
COX4I1 | COX4I1 | P13073 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 5 | 1 | 1 | 1 |
COX5A | COX5A | P20674 | Cytochrome c oxidase subunit 5A, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 14 | 5 | 5 | 1 |
CROCC | CROCC | Q5TZA2 | Rootletin | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 254 | 1583 | 184 | 184 | 0 |
CTBP1 | CTBP1 | Q13363 | C-terminal-binding protein 1 | chr4 | Not Cancer Driver | No | 1 | intact | 42 | 123 | 9 | 9 | 1 |
CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | Census, Compendium | Yes | 1 | hippie | 415 | 288 | 301 | 301 | 14 |
CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | Census, Compendium | Yes | 1 | intact, hippie | 123 | 167 | 23 | 23 | 3 |
CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | Not Cancer Driver | No | 1 | hippie | 188 | 372 | 41 | 41 | 3 |
CYC1 | CYC1 | P08574 | Cytochrome c1, heme protein, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 35 | 8 | 8 | 2 |
DAPK1_ENST00000622514 | DAPK1 | P53355 | Death-associated protein kinase 1 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 193 | 114 | 11 | 11 | 0 |
DDX58 | DDX58 | O95786 | Antiviral innate immune response receptor RIG-I | chr9 | Not Cancer Driver | No | 1 | hippie | 118 | 61 | 10 | 10 | 2 |
DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 132 | 514 | 82 | 82 | 0 |
DLD | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | intact | 67 | 17 | 0 | 0 | 10 |
DPP4 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 151 | 8 | 1 | 1 | 0 |
DTNA_ENST00000444659 | DTNA | Q9Y4J8 | Dystrobrevin alpha | chr18 | Not Cancer Driver | No | 1 | hippie | 162 | 412 | 86 | 86 | 0 |
DVL2 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | Not Cancer Driver | No | 1 | hippie | 96 | 514 | 64 | 64 | 0 |
DYRK3 | DYRK3 | O43781 | Dual specificity tyrosine-phosphorylation-regulated kinase 3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 87 | 193 | 20 | 20 | 0 |
EAPP | EAPP | Q56P03 | E2F-associated phosphoprotein | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 210 | 27 | 27 | 0 |
ECD_ENST00000372979 | ECD | O95905 | Protein ecdysoneless homolog | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 254 | 26 | 26 | 0 |
ECT2 | ECT2 | Q9H8V3 | Protein ECT2 | chr3 | Not Cancer Driver | No | 1 | hippie | 104 | 284 | 33 | 33 | 0 |
EFTUD2 | EFTUD2 | Q15029 | 116 kDa U5 small nuclear ribonucleoprotein component | chr17 | Compendium | Yes | 1 | hippie | 132 | 179 | 30 | 30 | 3 |
EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
EIF1B | EIF1B | O60739 | Eukaryotic translation initiation factor 1b | chr3 | Not Cancer Driver | No | 1 | hippie | 12 | 6 | 0 | 0 | 0 |
EIF4A2 | EIF4A2 | Q14240 | Eukaryotic initiation factor 4A-II | chr3 | Census | Yes | 1 | hippie, biogrid | 77 | 27 | 14 | 14 | 0 |
EIF6_ENST00000374436 | EIF6 | P56537 | Eukaryotic translation initiation factor 6 | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 17 | 3 | 3 | 0 |
ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 69 | 43 | 5 | 5 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 121 | 195 | 27 | 27 | 2 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 90 | 92 | 11 | 11 | 1 |
EXOC4 | EXOC4 | Q96A65 | Exocyst complex component 4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 164 | 133 | 33 | 33 | 0 |
FAM160A2_ENST00000449352 | FHIP1B | Q8N612 | FHF complex subunit HOOK interacting protein 1B | chr11 | Not Cancer Driver | No | 1 | intact | 129 | 415 | 54 | 54 | 0 |
FAM9C_ENST00000380625 | FAM9C | Q8IZT9 | Protein FAM9C | chrX | Not Cancer Driver | No | 2 | intact, hippie | 26 | 157 | 23 | 23 | 0 |
FASN | FASN | P49327 | Fatty acid synthase | chr17 | Not Cancer Driver | No | 1 | hippie | 291 | 309 | 42 | 42 | 0 |
FBP1_ENST00000375326 | FBP1 | P09467 | Fructose-1,6-bisphosphatase 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 33 | 19 | 0 | 0 | 4 |
FBXO5 | FBXO5 | Q9UKT4 | F-box only protein 5 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 48 | 113 | 13 | 13 | 0 |
FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | Census, Compendium | Yes | 1 | hippie | 322 | 230 | 38 | 38 | 0 |
FGA | FGA | P02671 | Fibrinogen alpha chain | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 245 | 522 | 149 | 149 | 7 |
FGF11 | FGF11 | Q92914 | Fibroblast growth factor 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 20 | 68 | 5 | 5 | 0 |
FKBP3_ENST00000396062 | FKBP3 | Q00688 | Peptidyl-prolyl cis-trans isomerase FKBP3 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 131 | 17 | 17 | 0 |
FKBP4 | FKBP4 | Q02790 | Peptidyl-prolyl cis-trans isomerase FKBP4 | chr12 | Not Cancer Driver | No | 1 | hippie | 46 | 134 | 12 | 12 | 0 |
FKBP5 | FKBP5 | Q13451 | Peptidyl-prolyl cis-trans isomerase FKBP5 | chr6 | Not Cancer Driver | No | 1 | hippie | 70 | 150 | 20 | 20 | 0 |
FN1 | FN1 | P02751 | Fibronectin | chr2 | Compendium | Yes | 1 | intact, hippie | 394 | 1243 | 185 | 185 | 8 |
FOS | FOS | P01100 | Protein c-Fos | chr14 | Not Cancer Driver | No | 1 | hippie | 45 | 245 | 33 | 33 | 0 |
FTSJ1 | FTSJ1 | Q9UET6 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase | chrX | Not Cancer Driver | No | 1 | intact, hippie | 44 | 89 | 14 | 14 | 0 |
FURIN_ENST00000610579 | FURIN | P09958 | Furin | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 93 | 283 | 35 | 35 | 0 |
GATA4_ENST00000335135 | GATA4 | P43694 | Transcription factor GATA-4 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 48 | 301 | 34 | 34 | 18 |
GFM1_ENST00000486715 | GFM1 | Q96RP9 | Elongation factor G, mitochondrial | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 74 | 79 | 7 | 7 | 4 |
GPC1 | GPC1 | P35052 | Glypican-1 | chr2 | Not Cancer Driver | No | 1 | hippie | 58 | 166 | 14 | 14 | 0 |
HDAC4 | HDAC4 | P56524 | Histone deacetylase 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 182 | 749 | 132 | 132 | 0 |
HDAC8 | HDAC8 | Q9BY41 | Histone deacetylase 8 | chrX | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 54 | 32 | 4 | 4 | 4 |
HDDC3_ENST00000646620 | HDDC3 | Q8N4P3 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 13 | 76 | 9 | 9 | 0 |
HIST2H2BE | H2BC21 | Q16778 | Histone H2B type 2-E | chr1 | Not Cancer Driver | No | 1 | intact | 47 | 77 | 30 | 30 | 0 |
HLA-B | HLA-B | P01889 | HLA class I histocompatibility antigen, B alpha chain | chr6 | Compendium | Yes | 1 | hippie | 78 | 169 | 34 | 34 | 0 |
HOMER1 | HOMER1 | Q86YM7 | Homer protein homolog 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 243 | 32 | 32 | 0 |
HOMER2 | HOMER2 | Q9NSB8 | Homer protein homolog 2 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 233 | 32 | 32 | 1 |
HOOK2 | HOOK2 | Q96ED9 | Protein Hook homolog 2 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 94 | 487 | 62 | 62 | 0 |
HOOK3 | HOOK3 | Q86VS8 | Protein Hook homolog 3 | chr8 | Census | Yes | 1 | hippie | 79 | 493 | 55 | 55 | 0 |
HSF1 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 335 | 37 | 37 | 0 |
HSF2 | HSF2 | Q03933 | Heat shock factor protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 64 | 292 | 37 | 37 | 0 |
HSF4 | HSF4 | Q9ULV5 | Heat shock factor protein 4 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 37 | 327 | 25 | 25 | 4 |
HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | Census, Compendium | Yes | 1 | hippie | 106 | 257 | 37 | 37 | 0 |
HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 100 | 254 | 43 | 43 | 0 |
HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 118 | 8 | 8 | 20 |
HSPB8 | HSPB8 | Q9UJY1 | Heat shock protein beta-8 | chr12 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 40 | 130 | 31 | 31 | 5 |
HTRA4 | HTRA4 | P83105 | Serine protease HTRA4 | chr8 | Not Cancer Driver | No | 1 | hippie | 57 | 15 | 0 | 0 | 0 |
IFIT3_ENST00000371811 | IFIT3 | O14879 | Interferon-induced protein with tetratricopeptide repeats 3 | chr10 | Not Cancer Driver | No | 1 | hippie | 47 | 143 | 11 | 11 | 0 |
IKBIP_ENST00000342502 | IKBIP | Q70UQ0 | Inhibitor of nuclear factor kappa-B kinase-interacting protein | chr12 | Not Cancer Driver | No | 1 | hippie | 53 | 69 | 8 | 8 | 0 |
IKBKE | IKBKE | Q14164 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 108 | 76 | 13 | 13 | 0 |
IMP3_ENST00000403490 | IMP3 | Q9NV31 | U3 small nucleolar ribonucleoprotein protein IMP3 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 1 | 0 | 0 | 0 |
INSIG1 | INSIG1 | O15503 | Insulin-induced gene 1 protein | chr7 | Not Cancer Driver | No | 1 | hippie | 37 | 43 | 1 | 1 | 0 |
INSIG2 | INSIG2 | Q9Y5U4 | Insulin-induced gene 2 protein | chr2 | Not Cancer Driver | No | 1 | hippie | 47 | 11 | 3 | 3 | 0 |
IQGAP1 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 183 | 351 | 35 | 35 | 0 |
ISG15 | ISG15 | P05161 | Ubiquitin-like protein ISG15 | chr1 | Not Cancer Driver | No | 1 | hippie | 12 | 24 | 2 | 2 | 0 |
JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 2 | hippie, biogrid | 35 | 281 | 25 | 25 | 0 |
JUNB | JUNB | P17275 | Transcription factor JunB | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 305 | 16 | 16 | 0 |
JUND | JUND | P17535 | Transcription factor JunD | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 313 | 19 | 19 | 0 |
KCNE1_ENST00000399284 | KCNE1 | P15382 | Potassium voltage-gated channel subfamily E member 1 | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 35 | 24 | 10 | 10 | 9 |
KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 291 | 28 | 28 | 3 |
KDM6B_ENST00000448097 | KDM6B | O15054 | Lysine-specific demethylase 6B | chr17 | Not Cancer Driver | No | 1 | hippie | 189 | 1278 | 142 | 142 | 2 |
KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
KIF20A | KIF20A | O95235 | Kinesin-like protein KIF20A | chr5 | Not Cancer Driver | No | 1 | hippie | 79 | 340 | 40 | 40 | 1 |
KIF5B | KIF5B | P33176 | Kinesin-1 heavy chain | chr10 | Census, Compendium | Yes | 1 | hippie, biogrid | 122 | 586 | 67 | 67 | 0 |
KIFC3_ENST00000379655 | KIFC3 | Q9BVG8 | Kinesin-like protein KIFC3 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 84 | 487 | 42 | 42 | 0 |
KLF10 | KLF10 | Q13118 | Krueppel-like factor 10 | chr8 | Not Cancer Driver | No | 1 | hippie | 59 | 349 | 46 | 46 | 0 |
KLF3 | KLF3 | P57682 | Krueppel-like factor 3 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 53 | 243 | 38 | 38 | 0 |
KLF9 | KLF9 | Q13886 | Krueppel-like factor 9 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 34 | 154 | 24 | 24 | 0 |
KLK6 | KLK6 | Q92876 | Kallikrein-6 | chr19 | Not Cancer Driver | No | 1 | hippie | 62 | 28 | 12 | 12 | 0 |
KXD1_ENST00000222307 | KXD1 | Q9BQD3 | KxDL motif-containing protein 1 | chr19 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 24 | 104 | 17 | 17 | 0 |
KYNU_ENST00000409512 | KYNU | Q16719 | Kynureninase | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 103 | 20 | 5 | 5 | 1 |
LCA5L_ENST00000288350 | LCA5L | O95447 | Lebercilin-like protein | chr21 | Not Cancer Driver | No | 2 | intact, hippie | 58 | 529 | 45 | 45 | 0 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 2 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
LURAP1 | LURAP1 | Q96LR2 | Leucine rich adaptor protein 1 | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 30 | 169 | 18 | 18 | 0 |
MAD1L1_ENST00000399654 | MAD1L1 | Q9Y6D9 | Mitotic spindle assembly checkpoint protein MAD1 | chr7 | Not Cancer Driver | No | 1 | hippie | 117 | 526 | 77 | 77 | 0 |
MAGEA11 | MAGEA11 | P43364 | Melanoma-associated antigen 11 | chrX | Not Cancer Driver | No | 1 | hippie | 115 | 217 | 49 | 49 | 0 |
MAGED2 | MAGED2 | Q9UNF1 | Melanoma-associated antigen D2 | chrX | Not Cancer Driver | No | 1 | hippie | 99 | 326 | 53 | 53 | 1 |
MAP3K7 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 104 | 333 | 66 | 66 | 6 |
MARCKS | MARCKS | P29966 | Myristoylated alanine-rich C-kinase substrate | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 328 | 14 | 14 | 0 |
MAST2 | MAST2 | Q6P0Q8 | Microtubule-associated serine/threonine-protein kinase 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 187 | 1326 | 133 | 133 | 0 |
MCC_ENST00000302475 | MCC | P23508 | Colorectal mutant cancer protein | chr5 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 136 | 589 | 92 | 92 | 0 |
MCM2 | MCM2 | P49736 | DNA replication licensing factor MCM2 | chr3 | Not Cancer Driver | No | 1 | hippie | 104 | 275 | 38 | 38 | 1 |
MCM3_ENST00000229854 | MCM3 | P25205 | DNA replication licensing factor MCM3 | chr6 | Not Cancer Driver | No | 1 | hippie | 92 | 310 | 47 | 47 | 0 |
MDC1 | MDC1 | Q14676 | Mediator of DNA damage checkpoint protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 249 | 1829 | 223 | 223 | 0 |
MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | hippie | 56 | 297 | 37 | 37 | 0 |
METTL14 | METTL14 | Q9HCE5 | N6-adenosine-methyltransferase non-catalytic subunit | chr4 | Not Cancer Driver | No | 1 | hippie | 60 | 224 | 26 | 26 | 0 |
METTL2B | METTL2B | Q6P1Q9 | tRNA N(3)-methylcytidine methyltransferase METTL2B | chr7 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 53 | 65 | 9 | 9 | 0 |
MFN2_ENST00000444836 | MFN2 | O95140 | Mitofusin-2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 81 | 9 | 9 | 20 |
MN1 | MN1 | Q10571 | Transcriptional activator MN1 | chr22 | Census | Yes | 1 | hippie | 148 | 1283 | 140 | 140 | 0 |
MOV10_ENST00000357443 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 101 | 8 | 8 | 0 |
MST1R | MST1R | Q04912 | Macrophage-stimulating protein receptor | chr3 | Not Cancer Driver | No | 1 | intact | 178 | 182 | 27 | 27 | 1 |
MTCH1 | MTCH1 | Q9NZJ7 | Mitochondrial carrier homolog 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 102 | 2 | 2 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
MYH7B | MYH7B | A7E2Y1 | Myosin-7B | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 294 | 1103 | 138 | 138 | 0 |
MYH9 | MYH9 | P35579 | Myosin-9 | chr22 | Census, Compendium | Yes | 1 | intact, hippie | 310 | 1120 | 160 | 160 | 17 |
MYO18A | MYO18A | Q92614 | Unconventional myosin-XVIIIa | chr17 | Not Cancer Driver | No | 1 | hippie | 268 | 1237 | 176 | 176 | 0 |
MYO5C | MYO5C | Q9NQX4 | Unconventional myosin-Vc | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 204 | 394 | 43 | 43 | 0 |
NAA40 | NAA40 | Q86UY6 | N-alpha-acetyltransferase 40 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 30 | 3 | 3 | 0 |
NDE1_ENST00000396354 | NDE1 | Q9NXR1 | Nuclear distribution protein nudE homolog 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 316 | 42 | 42 | 0 |
NDEL1 | NDEL1 | Q9GZM8 | Nuclear distribution protein nudE-like 1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 202 | 16 | 16 | 0 |
NDUFB10 | NDUFB10 | O96000 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 33 | 1 | 1 | 1 |
NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 150 | 711 | 79 | 79 | 0 |
NEK2 | NEK2 | P51955 | Serine/threonine-protein kinase Nek2 | chr1 | Not Cancer Driver | No | 1 | hippie | 61 | 92 | 19 | 19 | 0 |
NES | NES | P48681 | Nestin | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 271 | 1474 | 253 | 253 | 0 |
NKX2-5 | NKX2-5 | P52952 | Homeobox protein Nkx-2.5 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 48 | 181 | 22 | 22 | 55 |
NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 169 | 40 | 4 | 4 | 15 |
NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
NUF2_ENST00000367900 | NUF2 | Q9BZD4 | Kinetochore protein Nuf2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 97 | 74 | 20 | 20 | 0 |
NUP54 | NUP54 | Q7Z3B4 | Nucleoporin p54 | chr4 | Not Cancer Driver | No | 1 | hippie | 42 | 233 | 25 | 25 | 0 |
NXF1_ENST00000294172 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 100 | 163 | 32 | 32 | 0 |
OBSL1 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 233 | 553 | 60 | 60 | 0 |
OGA | OGA | O60502 | Protein O-GlcNAcase | chr10 | Not Cancer Driver | No | 1 | hippie | 89 | 241 | 15 | 15 | 0 |
OIP5 | OIP5 | O43482 | Protein Mis18-beta | chr15 | Not Cancer Driver | No | 1 | hippie | 31 | 65 | 7 | 7 | 0 |
OPA1_ENST00000392438 | OPA1 | O60313 | Dynamin-like 120 kDa protein, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 114 | 131 | 17 | 17 | 60 |
OSTF1 | OSTF1 | Q92882 | Osteoclast-stimulating factor 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 51 | 2 | 2 | 0 |
PAN2_ENST00000548043 | PAN2 | Q504Q3 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2 | chr12 | Not Cancer Driver | No | 1 | hippie | 139 | 78 | 10 | 10 | 0 |
PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 11 | 30 | 0 | 0 | 5 |
PAXIP1 | PAXIP1 | Q6ZW49 | PAX-interacting protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 120 | 461 | 39 | 39 | 0 |
PBX3 | PBX3 | P40426 | Pre-B-cell leukemia transcription factor 3 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 59 | 290 | 40 | 40 | 0 |
PCLAF | PCLAF | Q15004 | PCNA-associated factor | chr15 | Not Cancer Driver | No | 1 | hippie | 20 | 111 | 20 | 20 | 0 |
PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 43 | 6 | 6 | 20 |
PDIA4 | PDIA4 | P13667 | Protein disulfide-isomerase A4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 147 | 22 | 22 | 0 |
PDLIM7 | PDLIM7 | Q9NR12 | PDZ and LIM domain protein 7 | chr5 | Not Cancer Driver | No | 1 | hippie | 48 | 244 | 20 | 20 | 0 |
PEBP1 | PEBP1 | P30086 | Phosphatidylethanolamine-binding protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 76 | 13 | 13 | 0 |
PGAM1 | PGAM1 | P18669 | Phosphoglycerate mutase 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 70 | 5 | 5 | 0 |
PHF21A | PHF21A | Q96BD5 | PHD finger protein 21A | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 546 | 68 | 68 | 0 |
PHLDB3 | PHLDB3 | Q6NSJ2 | Pleckstrin homology-like domain family B member 3 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 74 | 462 | 50 | 50 | 0 |
PIH1D1 | PIH1D1 | Q9NWS0 | PIH1 domain-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 157 | 13 | 13 | 0 |
PIM3 | PIM3 | Q86V86 | Serine/threonine-protein kinase pim-3 | chr22 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 24 | 9 | 0 | 0 | 0 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
PPP1CB_ENST00000358506 | PPP1CB | P62140 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 47 | 25 | 5 | 5 | 5 |
PPP1CC_ENST00000335007 | PPP1CC | P36873 | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 26 | 23 | 4 | 4 | 0 |
PRDX1_ENST00000319248 | PRDX1 | Q06830 | Peroxiredoxin-1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 40 | 5 | 5 | 0 |
PRKAG2 | PRKAG2 | Q9UGJ0 | 5'-AMP-activated protein kinase subunit gamma-2 | chr7 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 76 | 240 | 45 | 45 | 7 |
PRKD1_ENST00000616995 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | Census | Yes | 1 | hippie | 201 | 189 | 33 | 33 | 2 |
PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 78 | 15 | 15 | 31 |
PRPF8 | PRPF8 | Q6P2Q9 | Pre-mRNA-processing-splicing factor 8 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 255 | 225 | 26 | 26 | 8 |
PSMA2 | PSMA2 | P25787 | Proteasome subunit alpha type-2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 0 | 0 | 0 | 0 |
PSMA6 | PSMA6 | P60900 | Proteasome subunit alpha type-6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 2 | 1 | 1 | 0 |
PSMC5 | PSMC5 | P62195 | 26S proteasome regulatory subunit 8 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 52 | 64 | 6 | 6 | 0 |
PTMS_ENST00000309083 | PTMS | P20962 | Parathymosin | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 102 | 10 | 10 | 0 |
RAD18 | RAD18 | Q9NS91 | E3 ubiquitin-protein ligase RAD18 | chr3 | Not Cancer Driver | No | 1 | hippie | 59 | 328 | 43 | 43 | 0 |
RAD21 | RAD21 | O60216 | Double-strand-break repair protein rad21 homolog | chr8 | Census, Compendium | Yes | 1 | hippie | 115 | 421 | 74 | 74 | 3 |
RBM8A_ENST00000632555 | RBM8A | Q9Y5S9 | RNA-binding protein 8A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 135 | 32 | 32 | 0 |
RBMXL1 | RBMXL1 | Q96E39 | RNA binding motif protein, X-linked-like-1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 371 | 75 | 75 | 0 |
RCOR1 | RCOR1 | Q9UKL0 | REST corepressor 1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 324 | 28 | 28 | 0 |
RCOR3_ENST00000367005 | RCOR3 | Q9P2K3 | REST corepressor 3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 332 | 45 | 45 | 0 |
RHOBTB1 | RHOBTB1 | O94844 | Rho-related BTB domain-containing protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 95 | 121 | 19 | 19 | 0 |
RHOBTB2_ENST00000251822 | RHOBTB2 | Q9BYZ6 | Rho-related BTB domain-containing protein 2 | chr8 | Not Cancer Driver | No | 1 | hippie | 99 | 131 | 18 | 18 | 6 |
RHOH_ENST00000617441 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 41 | 12 | 3 | 3 | 0 |
RHOU | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 63 | 6 | 6 | 0 |
RHOV | RHOV | Q96L33 | Rho-related GTP-binding protein RhoV | chr15 | Not Cancer Driver | No | 1 | hippie | 25 | 47 | 5 | 5 | 0 |
RIN3 | RIN3 | Q8TB24 | Ras and Rab interactor 3 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 137 | 417 | 61 | 61 | 0 |
RIPK3 | RIPK3 | Q9Y572 | Receptor-interacting serine/threonine-protein kinase 3 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 66 | 295 | 39 | 39 | 0 |
RND3_ENST00000263895 | RND3 | P61587 | Rho-related GTP-binding protein RhoE | chr2 | Not Cancer Driver | No | 1 | hippie | 36 | 70 | 10 | 10 | 0 |
RNF181 | RNF181 | Q9P0P0 | E3 ubiquitin-protein ligase RNF181 | chr2 | Not Cancer Driver | No | 1 | hippie | 15 | 63 | 8 | 8 | 0 |
RNF2 | RNF2 | Q99496 | E3 ubiquitin-protein ligase RING2 | chr1 | Not Cancer Driver | No | 1 | hippie | 40 | 203 | 22 | 22 | 0 |
RNF20 | RNF20 | Q5VTR2 | E3 ubiquitin-protein ligase BRE1A | chr9 | Not Cancer Driver | No | 1 | hippie | 126 | 561 | 64 | 64 | 0 |
RPTOR | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | Not Cancer Driver | No | 1 | hippie | 176 | 241 | 21 | 21 | 0 |
RRAGD | RRAGD | Q9NQL2 | Ras-related GTP-binding protein D | chr6 | Not Cancer Driver | No | 1 | hippie | 42 | 83 | 5 | 5 | 0 |
RXRA | RXRA | P19793 | Retinoic acid receptor RXR-alpha | chr9 | Compendium | Yes | 1 | hippie | 90 | 184 | 26 | 26 | 0 |
S100A2_ENST00000368709 | S100A2 | P29034 | Protein S100-A2 | chr1 | Not Cancer Driver | No | 1 | hippie | 16 | 6 | 2 | 2 | 0 |
S100A4_ENST00000354332 | S100A4 | P26447 | Protein S100-A4 | chr1 | Not Cancer Driver | No | 1 | hippie | 9 | 6 | 2 | 2 | 0 |
SEC23IP | SEC23IP | Q9Y6Y8 | SEC23-interacting protein | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 112 | 371 | 40 | 40 | 0 |
SF3A2 | SF3A2 | Q15428 | Splicing factor 3A subunit 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 382 | 21 | 21 | 0 |
SGF29 | SGF29 | Q96ES7 | SAGA-associated factor 29 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 31 | 131 | 17 | 17 | 0 |
SHMT2 | SHMT2 | P34897 | Serine hydroxymethyltransferase, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 58 | 5 | 5 | 1 |
SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | Census, Compendium | Yes | 1 | hippie | 97 | 111 | 19 | 19 | 5 |
SMARCA2 | SMARCA2 | P51531 | Probable global transcription activator SNF2L2 | chr9 | Not Cancer Driver | No | 1 | hippie | 273 | 1009 | 160 | 160 | 42 |
SNAPIN | SNAPIN | O95295 | SNARE-associated protein Snapin | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 9 | 62 | 5 | 5 | 0 |
SNRNP70 | SNRNP70 | P08621 | U1 small nuclear ribonucleoprotein 70 kDa | chr19 | Not Cancer Driver | No | 1 | hippie | 38 | 416 | 37 | 37 | 0 |
SOAT1 | SOAT1 | P35610 | Sterol O-acyltransferase 1 | chr1 | Not Cancer Driver | No | 1 | intact | 73 | 49 | 4 | 4 | 0 |
SOD1 | SOD1 | P00441 | Superoxide dismutase [Cu-Zn] | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 93 | 9 | 9 | 79 |
SP1 | SP1 | P08047 | Transcription factor Sp1 | chr12 | Not Cancer Driver | No | 1 | hippie | 96 | 599 | 71 | 71 | 0 |
SPAG9 | SPAG9 | O60271 | C-Jun-amino-terminal kinase-interacting protein 4 | chr17 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 128 | 841 | 81 | 81 | 0 |
SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | Census | Yes | 1 | hippie | 53 | 130 | 11 | 11 | 1 |
STAT5B | STAT5B | P51692 | Signal transducer and activator of transcription 5B | chr17 | Census, Compendium | Yes | 1 | intact, hippie | 93 | 144 | 19 | 19 | 5 |
STMN1_ENST00000357865 | STMN1 | P16949 | Stathmin | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 15 | 149 | 15 | 15 | 0 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 9 | 69 | 6 | 6 | 0 |
SUMO4 | SUMO4 | Q6EEV6 | Small ubiquitin-related modifier 4 | chr6 | Not Cancer Driver | No | 1 | hippie | 7 | 69 | 4 | 4 | 0 |
SYCE1_ENST00000343131 | SYCE1 | Q8N0S2 | Synaptonemal complex central element protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 70 | 251 | 50 | 50 | 0 |
SYDE2 | SYDE2 | Q5VT97 | Rho GTPase-activating protein SYDE2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 136 | 693 | 69 | 69 | 0 |
TAB2_ENST00000637181 | TAB2 | Q9NYJ8 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 87 | 573 | 73 | 73 | 2 |
TBCD | TBCD | Q9BTW9 | Tubulin-specific chaperone D | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 156 | 60 | 9 | 9 | 11 |
TET2 | TET2 | Q6N021 | Methylcytosine dioxygenase TET2 | chr4 | Census, Compendium | Yes | 1 | hippie | 191 | 1663 | 176 | 176 | 1 |
TFPT | TFPT | P0C1Z6 | TCF3 fusion partner | chr19 | Census | Yes | 5 | intact, hippie, biogrid | 41 | 237 | 41 | 41 | 0 |
THAP1 | THAP1 | Q9NVV9 | THAP domain-containing protein 1 | chr8 | Not Cancer Driver | No | 2 | intact, hippie | 19 | 76 | 8 | 8 | 45 |
THAP7_ENST00000399133 | THAP7 | Q9BT49 | THAP domain-containing protein 7 | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 34 | 214 | 24 | 24 | 0 |
THOC1 | THOC1 | Q96FV9 | THO complex subunit 1 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 280 | 26 | 26 | 0 |
TIAF1 | MYO18A | O95411 | Putative TGFB1-induced anti-apoptotic factor 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 16 | 30 | 5 | 5 | 0 |
TKT_ENST00000462138 | TKT | P29401 | Transketolase | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 86 | 7 | 7 | 1 |
TLK1 | TLK1 | Q9UKI8 | Serine/threonine-protein kinase tousled-like 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 103 | 388 | 53 | 53 | 0 |
TMOD1_ENST00000395211 | TMOD1 | P28289 | Tropomodulin-1 | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 41 | 195 | 29 | 29 | 0 |
TMOD2 | TMOD2 | Q9NZR1 | Tropomodulin-2 | chr15 | Not Cancer Driver | No | 1 | hippie | 33 | 216 | 22 | 22 | 0 |
TMPO | TMPO | P42166 | Lamina-associated polypeptide 2, isoform alpha | chr12 | Not Cancer Driver | No | 1 | hippie | 78 | 412 | 52 | 52 | 0 |
TNF | TNF | P01375 | Tumor necrosis factor | chr6 | Not Cancer Driver | No | 1 | hippie | 24 | 45 | 3 | 3 | 0 |
TNNI1_ENST00000336092 | TNNI1 | P19237 | Troponin I, slow skeletal muscle | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 72 | 8 | 8 | 0 |
TNNT1 | TNNT1 | P13805 | Troponin T, slow skeletal muscle | chr19 | Not Cancer Driver | No | 2 | intact, hippie | 61 | 240 | 55 | 55 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
TP73 | TP73 | O15350 | Tumor protein p73 | chr1 | Not Cancer Driver | No | 1 | hippie | 82 | 443 | 55 | 55 | 0 |
TPM1_ENST00000403994 | TPM1 | P09493 | Tropomyosin alpha-1 chain | chr15 | Not Cancer Driver | No | 4 | hippie, biogrid | 33 | 234 | 29 | 29 | 8 |
TPM2 | TPM2 | P07951 | Tropomyosin beta chain | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 39 | 232 | 35 | 35 | 15 |
TPM3 | TPM3 | P06753 | Tropomyosin alpha-3 chain | chr1 | Census | Yes | 2 | intact, hippie | 35 | 230 | 27 | 27 | 21 |
TPM4_ENST00000300933 | TPM4 | P67936 | Tropomyosin alpha-4 chain | chr19 | Census | Yes | 3 | intact, hippie, biogrid | 28 | 216 | 28 | 28 | 0 |
TRAP1 | TRAP1 | Q12931 | Heat shock protein 75 kDa, mitochondrial | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 74 | 110 | 11 | 11 | 0 |
TRIM24 | TRIM24 | O15164 | Transcription intermediary factor 1-alpha | chr7 | Census, Compendium | Yes | 1 | intact, hippie, biogrid | 120 | 537 | 61 | 61 | 0 |
TRIM26 | TRIM26 | Q12899 | Tripartite motif-containing protein 26 | chr6 | Not Cancer Driver | No | 1 | hippie | 67 | 153 | 16 | 16 | 0 |
TRIM27 | TRIM27 | P14373 | Zinc finger protein RFP | chr6 | Census | Yes | 1 | intact, hippie | 59 | 87 | 11 | 11 | 0 |
TRIM33 | TRIM33 | Q9UPN9 | E3 ubiquitin-protein ligase TRIM33 | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 110 | 617 | 51 | 51 | 0 |
TRIM37 | TRIM37 | O94972 | E3 ubiquitin-protein ligase TRIM37 | chr17 | Not Cancer Driver | No | 1 | hippie | 119 | 492 | 60 | 60 | 3 |
TRIP6 | TRIP6 | Q15654 | Thyroid receptor-interacting protein 6 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 62 | 268 | 19 | 19 | 0 |
TSKS | TSKS | Q9UJT2 | Testis-specific serine kinase substrate | chr19 | Not Cancer Driver | No | 1 | hippie | 123 | 479 | 100 | 100 | 0 |
TSSC4 | TSSC4 | Q9Y5U2 | Protein TSSC4 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 326 | 35 | 35 | 0 |
TUBA1A | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 59 | 52 | 11 | 11 | 8 |
UCHL1 | UCHL1 | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | chr4 | Not Cancer Driver | No | 1 | hippie | 33 | 34 | 7 | 7 | 4 |
UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 141 | 24 | 24 | 0 |
UNK | UNK | Q9C0B0 | RING finger protein unkempt homolog | chr17 | Not Cancer Driver | No | 1 | hippie | 79 | 511 | 46 | 46 | 0 |
UQCRC2 | UQCRC2 | P22695 | Cytochrome b-c1 complex subunit 2, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 48 | 13 | 13 | 1 |
VDAC1_ENST00000395047 | VDAC1 | P21796 | Voltage-dependent anion-selective channel protein 1 | chr5 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 38 | 36 | 4 | 4 | 0 |
VMP1 | VMP1 | Q96GC9 | Vacuole membrane protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 57 | 68 | 11 | 11 | 0 |
VPS52 | VPS52 | Q8N1B4 | Vacuolar protein sorting-associated protein 52 homolog | chr6 | Not Cancer Driver | No | 1 | hippie | 89 | 36 | 5 | 5 | 0 |
WASHC1 | WASHC1 | A8K0Z3 | WASH complex subunit 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 6 | 336 | 6 | 6 | 0 |
WFDC2 | WFDC2 | Q14508 | WAP four-disulfide core domain protein 2 | chr20 | Not Cancer Driver | No | 1 | hippie | 16 | 0 | 0 | 0 | 0 |
WTAP_ENST00000621533 | WTAP | Q15007 | Pre-mRNA-splicing regulator WTAP | chr6 | Not Cancer Driver | No | 1 | hippie | 60 | 305 | 50 | 50 | 0 |
ZBTB18_ENST00000622512 | ZBTB18 | Q99592 | Zinc finger and BTB domain-containing protein 18 | chr1 | Not Cancer Driver | No | 1 | intact | 78 | 236 | 25 | 25 | 0 |
ZFC3H1 | ZFC3H1 | O60293 | Zinc finger C3H1 domain-containing protein | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 210 | 1025 | 115 | 115 | 0 |
ZIC3 | ZIC3 | O60481 | Zinc finger protein ZIC 3 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 100 | 327 | 66 | 66 | 10 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|