Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | Census, Compendium | Yes | 1 | hippie | 139 | 604 | 73 | 73 | 2 |
ADH5 | ADH5 | P11766 | Alcohol dehydrogenase class-3 | chr4 | Not Cancer Driver | No | 1 | hippie | 36 | 2 | 1 | 1 | 0 |
AGBL2 | AGBL2 | Q5U5Z8 | Cytosolic carboxypeptidase 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 117 | 246 | 29 | 29 | 0 |
AGO1 | AGO1 | Q9UL18 | Protein argonaute-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 126 | 87 | 11 | 11 | 0 |
AGO2 | AGO2 | Q9UKV8 | Protein argonaute-2 | chr8 | Not Cancer Driver | No | 1 | hippie | 126 | 141 | 15 | 15 | 11 |
AHCY | AHCY | P23526 | Adenosylhomocysteinase | chr20 | Not Cancer Driver | No | 1 | hippie | 58 | 0 | 0 | 0 | 4 |
AKAP1_ENST00000539273 | AKAP1 | Q92667 | A-kinase anchor protein 1, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie | 107 | 537 | 67 | 67 | 0 |
AMPH | AMPH | P49418 | Amphiphysin | chr7 | Not Cancer Driver | No | 1 | hippie | 202 | 473 | 131 | 131 | 0 |
APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | Not Cancer Driver | No | 1 | hippie | 34 | 103 | 14 | 14 | 0 |
ASF1A | ASF1A | Q9Y294 | Histone chaperone ASF1A | chr6 | Not Cancer Driver | No | 1 | hippie | 18 | 69 | 2 | 2 | 0 |
ASPM | ASPM | Q8IZT6 | Abnormal spindle-like microcephaly-associated protein | chr1 | Not Cancer Driver | No | 1 | hippie | 554 | 424 | 67 | 67 | 0 |
ATF3_ENST00000366987 | ATF3 | P18847 | Cyclic AMP-dependent transcription factor ATF-3 | chr1 | Not Cancer Driver | No | 1 | hippie | 23 | 118 | 14 | 14 | 0 |
AURKA_ENST00000395915 | AURKA | O14965 | Aurora kinase A | chr20 | Not Cancer Driver | No | 1 | hippie | 36 | 178 | 21 | 21 | 0 |
BIN1 | BIN1 | O00499 | Myc box-dependent-interacting protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 65 | 456 | 42 | 42 | 5 |
BORCS8 | BORCS8 | Q96FH0 | BLOC-1-related complex subunit 8 | chr19 | Not Cancer Driver | No | 1 | hippie | 2 | 56 | 0 | 0 | 0 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
BRD8 | BRD8 | Q9H0E9 | Bromodomain-containing protein 8 | chr5 | Not Cancer Driver | No | 1 | hippie | 189 | 934 | 147 | 147 | 0 |
BUB1B | BUB1B | O60566 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta | chr15 | Census | Yes | 1 | hippie | 96 | 480 | 35 | 35 | 7 |
C6orf141 | C6orf141 | Q5SZD1 | Uncharacterized protein C6orf141 | chr6 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 12 | 226 | 9 | 9 | 0 |
CABLES1 | CABLES1 | Q8TDN4 | CDK5 and ABL1 enzyme substrate 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 58 | 334 | 23 | 23 | 0 |
CASP8AP2 | CASP8AP2 | Q9UKL3 | CASP8-associated protein 2 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 219 | 1501 | 178 | 178 | 0 |
CCDC96 | CCDC96 | Q2M329 | Coiled-coil domain-containing protein 96 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 308 | 41 | 41 | 0 |
CCNA2_ENST00000618014 | CCNA2 | P20248 | Cyclin-A2 | chr4 | Not Cancer Driver | No | 1 | hippie | 45 | 186 | 19 | 19 | 0 |
CCNB1 | CCNB1 | P14635 | G2/mitotic-specific cyclin-B1 | chr5 | Not Cancer Driver | No | 1 | hippie | 49 | 145 | 14 | 14 | 0 |
CCND1 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | Census, Compendium | Yes | 1 | hippie | 55 | 31 | 25 | 25 | 0 |
CCNE1 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | Census | Yes | 1 | hippie | 63 | 142 | 26 | 26 | 0 |
CCNG1_ENST00000393929 | CCNG1 | P51959 | Cyclin-G1 | chr5 | Not Cancer Driver | No | 1 | hippie | 25 | 0 | 0 | 0 | 0 |
CCNT1 | CCNT1 | O60563 | Cyclin-T1 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 85 | 495 | 61 | 61 | 0 |
CDC20 | CDC20 | Q12834 | Cell division cycle protein 20 homolog | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 44 | 198 | 15 | 15 | 0 |
CDK1 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 40 | 1 | 0 | 0 | 0 |
CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 0 |
CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | Census, Compendium | Yes | 1 | hippie | 48 | 121 | 30 | 30 | 0 |
CDT1 | CDT1 | Q9H211 | DNA replication factor Cdt1 | chr16 | Not Cancer Driver | No | 1 | hippie | 60 | 377 | 35 | 35 | 5 |
CEBPZ | CEBPZ | Q03701 | CCAAT/enhancer-binding protein zeta | chr2 | Not Cancer Driver | No | 1 | hippie | 95 | 488 | 44 | 44 | 0 |
CEP131 | CEP131 | Q9UPN4 | Centrosomal protein of 131 kDa | chr17 | Not Cancer Driver | No | 1 | hippie | 126 | 948 | 113 | 113 | 0 |
CFAP206 | CFAP206 | Q8IYR0 | Cilia- and flagella-associated protein 206 | chr6 | Not Cancer Driver | No | 1 | hippie | 130 | 92 | 18 | 18 | 0 |
CHD3_ENST00000330494 | CHD3 | Q12873 | Chromodomain-helicase-DNA-binding protein 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 235 | 1015 | 122 | 122 | 18 |
CHUK | CHUK | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | chr10 | Not Cancer Driver | No | 1 | hippie | 74 | 116 | 9 | 9 | 0 |
CIC | CIC | Q96RK0 | Protein capicua homolog | chr19 | Census, Compendium | Yes | 1 | hippie | 276 | 1550 | 266 | 266 | 0 |
CREBBP | CREBBP | Q92793 | CREB-binding protein | chr16 | Census, Compendium | Yes | 1 | hippie | 412 | 1796 | 247 | 247 | 33 |
CSNK2A1_ENST00000400217 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 71 | 75 | 8 | 8 | 4 |
CUL1_ENST00000602748 | CUL1 | Q13616 | Cullin-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 151 | 65 | 9 | 9 | 0 |
DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | Not Cancer Driver | No | 1 | hippie | 131 | 681 | 68 | 68 | 0 |
DAPK2 | DAPK2 | Q9UIK4 | Death-associated protein kinase 2 | chr15 | Not Cancer Driver | No | 1 | hippie | 55 | 53 | 9 | 9 | 0 |
DAXX_ENST00000266000 | DAXX | Q9UER7 | Death domain-associated protein 6 | chr6 | Census, Compendium | Yes | 1 | hippie | 106 | 549 | 81 | 81 | 0 |
DDX23 | DDX23 | Q9BUQ8 | Probable ATP-dependent RNA helicase DDX23 | chr12 | Not Cancer Driver | No | 1 | hippie | 121 | 426 | 71 | 71 | 0 |
DNAJB6 | DNAJB6 | O75190 | DnaJ homolog subfamily B member 6 | chr7 | Not Cancer Driver | No | 1 | hippie | 33 | 198 | 17 | 17 | 3 |
DNM3_ENST00000355305 | DNM3 | Q9UQ16 | Dynamin-3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 166 | 257 | 45 | 45 | 0 |
DPH1 | DPH1 | Q9BZG8 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 41 | 67 | 8 | 8 | 2 |
DSN1 | DSN1 | Q9H410 | Kinetochore-associated protein DSN1 homolog | chr20 | Not Cancer Driver | No | 2 | hippie, biogrid | 45 | 191 | 28 | 28 | 0 |
EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 334 | 1790 | 196 | 196 | 1 |
ETS2 | ETS2 | P15036 | Protein C-ets-2 | chr21 | Not Cancer Driver | No | 1 | hippie | 73 | 127 | 25 | 25 | 0 |
FBXO45 | FBXO45 | P0C2W1 | F-box/SPRY domain-containing protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 28 | 10 | 0 | 0 | 0 |
FLNA | FLNA | P21333 | Filamin-A | chrX | Census | Yes | 1 | hippie | 416 | 1456 | 214 | 214 | 28 |
FUS | FUS | P35637 | RNA-binding protein FUS | chr16 | Census | Yes | 1 | hippie | 51 | 524 | 51 | 51 | 20 |
GAS8 | GAS8 | O95995 | Dynein regulatory complex subunit 4 | chr16 | Not Cancer Driver | No | 1 | hippie | 54 | 232 | 29 | 29 | 1 |
GLS2 | GLS2 | Q9UI32 | Glutaminase liver isoform, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 108 | 9 | 9 | 0 |
HASPIN | HASPIN | Q8TF76 | Serine/threonine-protein kinase haspin | chr17 | Not Cancer Driver | No | 1 | hippie | 87 | 373 | 36 | 36 | 0 |
HCK_ENST00000534862 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | Not Cancer Driver | No | 1 | hippie | 112 | 124 | 25 | 25 | 0 |
HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 47 | 135 | 10 | 10 | 0 |
HDAC2 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 46 | 145 | 14 | 14 | 0 |
HECW2_ENST00000644256 | HECW2 | Q9P2P5 | E3 ubiquitin-protein ligase HECW2 | chr2 | Not Cancer Driver | No | 1 | hippie | 348 | 845 | 195 | 195 | 4 |
HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | Census | Yes | 1 | hippie | 118 | 435 | 51 | 51 | 0 |
HIPK2 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 154 | 686 | 96 | 96 | 0 |
HIPK3 | HIPK3 | Q9H422 | Homeodomain-interacting protein kinase 3 | chr11 | Not Cancer Driver | No | 1 | hippie | 128 | 559 | 51 | 51 | 0 |
HMGB1_ENST00000405805 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | Not Cancer Driver | No | 1 | intact, hippie | 25 | 203 | 20 | 20 | 0 |
HRAS | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | hippie | 107 | 16 | 4 | 4 | 18 |
HSPA4 | HSPA4 | P34932 | Heat shock 70 kDa protein 4 | chr5 | Not Cancer Driver | No | 1 | hippie | 80 | 351 | 24 | 24 | 0 |
HSPA9 | HSPA9 | P38646 | Stress-70 protein, mitochondrial | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 67 | 283 | 26 | 26 | 2 |
HSPB8 | HSPB8 | Q9UJY1 | Heat shock protein beta-8 | chr12 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 40 | 130 | 31 | 31 | 5 |
IER2_ENST00000587885 | IER2 | Q9BTL4 | Immediate early response gene 2 protein | chr19 | Not Cancer Driver | No | 3 | hippie, biogrid | 16 | 178 | 13 | 13 | 0 |
IGF2BP1 | IGF2BP1 | Q9NZI8 | Insulin-like growth factor 2 mRNA-binding protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 141 | 298 | 80 | 80 | 0 |
IKBKB | IKBKB | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | chr8 | Census, Compendium | Yes | 1 | hippie | 106 | 211 | 31 | 31 | 1 |
ITCH | ITCH | Q96J02 | E3 ubiquitin-protein ligase Itchy homolog | chr20 | Not Cancer Driver | No | 1 | hippie | 95 | 335 | 42 | 42 | 0 |
JPH1 | JPH1 | Q9HDC5 | Junctophilin-1 | chr8 | Not Cancer Driver | No | 1 | hippie | 131 | 421 | 89 | 89 | 0 |
JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
KAT2B | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | Not Cancer Driver | No | 1 | hippie | 107 | 266 | 27 | 27 | 0 |
KAT5_ENST00000377046 | KAT5 | Q92993 | Histone acetyltransferase KAT5 | chr11 | Not Cancer Driver | No | 1 | hippie | 65 | 173 | 21 | 21 | 3 |
KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | Not Cancer Driver | No | 1 | hippie | 67 | 291 | 28 | 28 | 3 |
KLC1_ENST00000348520 | KLC1 | Q07866 | Kinesin light chain 1 | chr14 | Not Cancer Driver | No | 1 | intact | 54 | 292 | 31 | 31 | 0 |
L3MBTL1 | L3MBTL1 | Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | chr20 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 116 | 447 | 40 | 40 | 0 |
LRPPRC | LRPPRC | P42704 | Leucine-rich PPR motif-containing protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 131 | 18 | 2 | 2 | 1 |
MAD2L1 | MAD2L1 | Q13257 | Mitotic spindle assembly checkpoint protein MAD2A | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 26 | 12 | 1 | 1 | 0 |
MAPK8_ENST00000374189 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | Not Cancer Driver | No | 1 | hippie | 64 | 94 | 9 | 9 | 0 |
MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 2 | intact, hippie | 56 | 297 | 37 | 37 | 0 |
MDM4 | MDM4 | O15151 | Protein Mdm4 | chr1 | Census, Compendium | Yes | 2 | intact, hippie, biogrid | 57 | 202 | 26 | 26 | 1 |
MED15 | MED15 | Q96RN5 | Mediator of RNA polymerase II transcription subunit 15 | chr22 | Not Cancer Driver | No | 1 | hippie | 95 | 558 | 72 | 72 | 0 |
MLF1_ENST00000355893 | MLF1 | P58340 | Myeloid leukemia factor 1 | chr3 | Census | Yes | 2 | hippie, biogrid | 40 | 243 | 37 | 37 | 0 |
MTHFSD | MTHFSD | Q2M296 | Methenyltetrahydrofolate synthase domain-containing protein | chr16 | Not Cancer Driver | No | 1 | hippie | 49 | 160 | 16 | 16 | 0 |
MUL1 | MUL1 | Q969V5 | Mitochondrial ubiquitin ligase activator of NFKB 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 48 | 16 | 2 | 2 | 0 |
MYCN | MYCN | P04198 | N-myc proto-oncogene protein | chr2 | Census, Compendium | Yes | 1 | hippie | 71 | 415 | 64 | 64 | 3 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
MYL9 | MYL9 | P24844 | Myosin regulatory light polypeptide 9 | chr20 | Not Cancer Driver | No | 1 | hippie | 34 | 82 | 19 | 19 | 0 |
N4BP2 | N4BP2 | Q86UW6 | NEDD4-binding protein 2 | chr4 | Census | Yes | 1 | hippie | 185 | 965 | 104 | 104 | 0 |
NCAPH2_ENST00000420993 | NCAPH2 | Q6IBW4 | Condensin-2 complex subunit H2 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 335 | 39 | 39 | 0 |
NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | Not Cancer Driver | No | 1 | hippie | 150 | 711 | 79 | 79 | 0 |
NEDD8 | NEDD8 | Q15843 | NEDD8 | chr14 | Not Cancer Driver | No | 1 | hippie | 10 | 36 | 5 | 5 | 0 |
NFYB | NFYB | P25208 | Nuclear transcription factor Y subunit beta | chr12 | Not Cancer Driver | No | 1 | hippie | 23 | 94 | 7 | 7 | 0 |
NFYC | NFYC | Q13952 | Nuclear transcription factor Y subunit gamma | chr1 | Not Cancer Driver | No | 1 | hippie | 46 | 320 | 32 | 32 | 0 |
NPRL3_ENST00000611875 | NPRL3 | Q12980 | GATOR complex protein NPRL3 | chr16 | Not Cancer Driver | No | 1 | hippie | 45 | 158 | 22 | 22 | 0 |
NQO1 | NQO1 | P15559 | NAD(P)H dehydrogenase [quinone] 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 21 | 10 | 1 | 1 | 0 |
OAZ1 | OAZ1 | P54368 | Ornithine decarboxylase antizyme 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 109 | 12 | 12 | 0 |
PAX6_ENST00000241001 | PAX6 | P26367 | Paired box protein Pax-6 | chr11 | Not Cancer Driver | No | 1 | hippie | 72 | 337 | 56 | 56 | 38 |
PFDN5 | PFDN5 | Q99471 | Prefoldin subunit 5 | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 3 | 0 | 0 | 0 |
PIAS1_ENST00000249636 | PIAS1 | O75925 | E3 SUMO-protein ligase PIAS1 | chr15 | Not Cancer Driver | No | 1 | hippie | 80 | 241 | 43 | 43 | 0 |
PIN1 | PIN1 | Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 17 | 115 | 12 | 12 | 0 |
PIWIL1 | PIWIL1 | Q96J94 | Piwi-like protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 202 | 172 | 37 | 37 | 0 |
PLAGL1_ENST00000367571 | PLAGL1 | Q9UM63 | Zinc finger protein PLAGL1 | chr6 | Not Cancer Driver | No | 1 | hippie | 49 | 217 | 24 | 24 | 0 |
PLK1 | PLK1 | P53350 | Serine/threonine-protein kinase PLK1 | chr16 | Not Cancer Driver | No | 1 | hippie | 87 | 119 | 13 | 13 | 0 |
PML | PML | P29590 | Protein PML | chr15 | Census, Compendium | Yes | 1 | hippie | 112 | 312 | 34 | 34 | 0 |
PMS2 | PMS2 | P54278 | Mismatch repair endonuclease PMS2 | chr7 | Census, Compendium | Yes | 1 | intact, hippie | 117 | 331 | 44 | 44 | 9 |
PPP1R13B | PPP1R13B | Q96KQ4 | Apoptosis-stimulating of p53 protein 1 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 115 | 821 | 92 | 92 | 0 |
PPP1R13L_ENST00000360957 | PPP1R13L | Q8WUF5 | RelA-associated inhibitor | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 117 | 657 | 90 | 90 | 0 |
PRELID2 | PRELID2 | Q8N945 | PRELI domain-containing protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 3 | 0 | 0 | 0 |
PRKACA | PRKACA | P17612 | cAMP-dependent protein kinase catalytic subunit alpha | chr19 | Census | Yes | 1 | hippie | 53 | 24 | 0 | 0 | 2 |
PRKACB_ENST00000370689 | PRKACB | P22694 | cAMP-dependent protein kinase catalytic subunit beta | chr1 | Not Cancer Driver | No | 1 | hippie | 50 | 26 | 6 | 6 | 4 |
PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | Compendium | Yes | 1 | hippie | 79 | 43 | 9 | 9 | 0 |
PRMT6 | PRMT6 | Q96LA8 | Protein arginine N-methyltransferase 6 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 43 | 71 | 7 | 7 | 0 |
RABL2A_ENST00000393166 | RABL2A | Q9UBK7 | Rab-like protein 2A | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 44 | 5 | 5 | 0 |
RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 34 | 13 | 0 | 0 | 0 |
RANBP9 | RANBP9 | Q96S59 | Ran-binding protein 9 | chr6 | Not Cancer Driver | No | 1 | hippie | 73 | 413 | 30 | 30 | 0 |
RB1 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | Census, Compendium | Yes | 1 | hippie | 140 | 282 | 32 | 32 | 22 |
RBX1 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | Not Cancer Driver | No | 1 | hippie | 10 | 18 | 1 | 1 | 0 |
RCHY1 | RCHY1 | Q96PM5 | RING finger and CHY zinc finger domain-containing protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 33 | 23 | 0 | 0 | 0 |
RNF144B | RNF144B | Q7Z419 | E3 ubiquitin-protein ligase RNF144B | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 32 | 4 | 1 | 1 | 0 |
RNF38 | RNF38 | Q9H0F5 | E3 ubiquitin-protein ligase RNF38 | chr9 | Not Cancer Driver | No | 1 | hippie | 70 | 348 | 47 | 47 | 0 |
RPL11 | RPL11 | P62913 | 60S ribosomal protein L11 | chr1 | Not Cancer Driver | No | 1 | hippie | 27 | 12 | 1 | 1 | 1 |
RPL5_ENST00000370321 | RPL5 | P46777 | 60S ribosomal protein L5 | chr1 | Census | Yes | 1 | hippie | 57 | 96 | 17 | 17 | 2 |
RPS14_ENST00000521466 | RPS14 | P62263 | 40S ribosomal protein S14 | chr5 | Not Cancer Driver | No | 1 | hippie | 14 | 96 | 13 | 13 | 0 |
RTCB | RTCB | Q9Y3I0 | RNA-splicing ligase RtcB homolog | chr22 | Not Cancer Driver | No | 1 | hippie | 57 | 74 | 7 | 7 | 0 |
RUNX2_ENST00000647337 | RUNX2 | Q13950 | Runt-related transcription factor 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 83 | 447 | 73 | 73 | 47 |
SASS6 | SASS6 | Q6UVJ0 | Spindle assembly abnormal protein 6 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 82 | 331 | 37 | 37 | 1 |
SIAH1_ENST00000394725 | SIAH1 | Q8IUQ4 | E3 ubiquitin-protein ligase SIAH1 | chr16 | Not Cancer Driver | No | 1 | hippie | 35 | 28 | 2 | 2 | 5 |
SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 70 | 435 | 31 | 31 | 0 |
SKP2 | SKP2 | Q13309 | S-phase kinase-associated protein 2 | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 52 | 52 | 6 | 6 | 0 |
SMAD2_ENST00000402690 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | Census, Compendium | Yes | 1 | hippie | 79 | 137 | 12 | 12 | 0 |
SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | Census, Compendium | Yes | 1 | hippie | 97 | 111 | 19 | 19 | 5 |
SMARCD2 | SMARCD2 | Q92925 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 58 | 251 | 26 | 26 | 0 |
SOCS1 | SOCS1 | O15524 | Suppressor of cytokine signaling 1 | chr16 | Census, Compendium | Yes | 1 | hippie, biogrid | 22 | 66 | 3 | 3 | 2 |
SOX2 | SOX2 | P48431 | Transcription factor SOX-2 | chr3 | Census | Yes | 1 | intact, hippie | 39 | 312 | 39 | 39 | 0 |
SP1 | SP1 | P08047 | Transcription factor Sp1 | chr12 | Not Cancer Driver | No | 1 | hippie | 96 | 599 | 71 | 71 | 0 |
SP3 | SP3 | Q02447 | Transcription factor Sp3 | chr2 | Not Cancer Driver | No | 1 | hippie | 66 | 587 | 37 | 37 | 0 |
SPSB1_ENST00000377399 | SPSB1 | Q96BD6 | SPRY domain-containing SOCS box protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 35 | 26 | 3 | 3 | 0 |
STAG1 | STAG1 | Q8WVM7 | Cohesin subunit SA-1 | chr3 | Census | Yes | 1 | hippie | 226 | 391 | 66 | 66 | 8 |
STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | Not Cancer Driver | No | 1 | hippie | 35 | 112 | 14 | 14 | 12 |
SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 10 | 76 | 7 | 7 | 0 |
TALDO1 | TALDO1 | P37837 | Transaldolase | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 31 | 4 | 4 | 0 |
TDG | TDG | Q13569 | G/T mismatch-specific thymine DNA glycosylase | chr12 | Not Cancer Driver | No | 1 | hippie | 75 | 185 | 31 | 31 | 0 |
TNK2_ENST00000333602 | TNK2 | Q07912 | Activated CDC42 kinase 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 137 | 593 | 81 | 81 | 0 |
TP53BP1_ENST00000263801 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 227 | 1632 | 190 | 190 | 0 |
TP53BP2 | TP53BP2 | Q13625 | Apoptosis-stimulating of p53 protein 2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 152 | 868 | 118 | 118 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
TP63 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | Census, Compendium | Yes | 5 | intact, hippie, biogrid | 229 | 398 | 143 | 143 | 28 |
TP73 | TP73 | O15350 | Tumor protein p73 | chr1 | Not Cancer Driver | No | 4 | intact, hippie | 82 | 443 | 55 | 55 | 0 |
TPM3 | TPM3 | P06753 | Tropomyosin alpha-3 chain | chr1 | Census | Yes | 1 | hippie | 35 | 230 | 27 | 27 | 21 |
TRAPPC11 | TRAPPC11 | Q7Z392 | Trafficking protein particle complex subunit 11 | chr4 | Not Cancer Driver | No | 1 | hippie | 109 | 44 | 5 | 5 | 1 |
TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
TRIM32 | TRIM32 | Q13049 | E3 ubiquitin-protein ligase TRIM32 | chr9 | Not Cancer Driver | No | 1 | hippie | 82 | 87 | 10 | 10 | 3 |
TRIM66_ENST00000299550 | TRIM66 | O15016 | Tripartite motif-containing protein 66 | chr11 | Not Cancer Driver | No | 1 | hippie | 58 | 723 | 32 | 32 | 0 |
TRMT11 | TRMT11 | Q7Z4G4 | tRNA (guanine(10)-N2)-methyltransferase homolog | chr6 | Not Cancer Driver | No | 1 | hippie | 38 | 45 | 3 | 3 | 0 |
TTLL5 | TTLL5 | Q6EMB2 | Tubulin polyglutamylase TTLL5 | chr14 | Not Cancer Driver | No | 1 | hippie | 165 | 692 | 82 | 82 | 1 |
UBC | UBC | P0CG48 | Polyubiquitin-C | chr12 | Not Cancer Driver | No | 1 | intact | 97 | 312 | 53 | 53 | 0 |
UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 1 | hippie | 16 | 16 | 3 | 3 | 0 |
UBE4B | UBE4B | O95155 | Ubiquitin conjugation factor E4 B | chr1 | Not Cancer Driver | No | 1 | hippie | 158 | 434 | 49 | 49 | 0 |
USP7 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | Not Cancer Driver | No | 1 | intact | 170 | 215 | 45 | 45 | 0 |
WT1_ENST00000379079 | WT1 | P19544-6 | Isoform 6 of Wilms tumor protein | chr11 | Census, Compendium | Yes | 1 | hippie | 69 | 194 | 43 | 43 | 0 |
WWOX | WWOX | Q9NZC7 | WW domain-containing oxidoreductase | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 79 | 108 | 9 | 9 | 3 |
WWP1 | WWP1 | Q9H0M0 | NEDD4-like E3 ubiquitin-protein ligase WWP1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 139 | 431 | 75 | 75 | 0 |
WWP2 | WWP2 | O00308 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | chr16 | Not Cancer Driver | No | 1 | hippie | 112 | 422 | 57 | 57 | 0 |
XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 140 | 33 | 9 | 9 | 0 |
YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | Not Cancer Driver | No | 3 | intact, hippie | 51 | 489 | 49 | 49 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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