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TP53BP2 ,TP53BP2 ,Q13625
  • Uniprot Accession= Q13625
  • Ensembl Transcript= ENST00000343537.11
  • Uniprot Name= TP53BP2
  • Name= Apoptosis-stimulating of p53 protein 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 112
  • Number of Interaction partner in biogrid: 52
  • Number of Interaction partner in hippie: 223
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 112 43 5 5 5
ADAMTS12 ADAMTS12 P58397 A disintegrin and metalloproteinase with thrombospondin motifs 12 chr5 Not Cancer Driver No 1 intact, hippie 504 374 128 128 0
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 Census Yes 1 hippie 248 1247 180 180 0
AL662899.2_ENST00000375880 CSNK2B Q5SRQ3 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 21 30 1 1 0
ALB ALB P02768 Albumin chr4 Compendium Yes 1 intact 162 6 0 0 3
AMOT AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 2 intact, hippie, biogrid 161 909 128 128 0
AMOTL2_ENST00000422605 AMOTL2 Q9Y2J4 Angiomotin-like protein 2 chr3 Not Cancer Driver No 1 hippie, biogrid 94 741 93 93 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 Not Cancer Driver No 1 intact, hippie 59 61 12 12 0
APC2_ENST00000233607 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 Not Cancer Driver No 1 hippie 117 1725 78 78 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 2 intact, hippie 128 418 71 71 17
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 Not Cancer Driver No 1 hippie 67 292 31 31 1
ARHGAP45_ENST00000313093 ARHGAP45 Q92619 Rho GTPase-activating protein 45 chr19 Not Cancer Driver No 1 intact 110 679 68 68 0
ARHGEF6 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX Not Cancer Driver No 1 intact, hippie 158 223 45 45 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 40 25 6 6 1
ATPAF2 ATPAF2 Q8N5M1 ATP synthase mitochondrial F1 complex assembly factor 2 chr17 Not Cancer Driver No 1 hippie 25 66 4 4 1
ATXN7_ENST00000487717 ATXN7 O15265 Ataxin-7 chr3 Not Cancer Driver No 1 hippie 95 797 82 82 0
AXIN1 AXIN1 O15169 Axin-1 chr16 Census, Compendium Yes 1 intact, hippie 120 619 88 88 4
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 17 112 9 9 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 Not Cancer Driver No 1 hippie 85 330 52 52 0
BCAS2 BCAS2 O75934 Pre-mRNA-splicing factor SPF27 chr1 Not Cancer Driver No 1 hippie 30 55 5 5 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 Not Cancer Driver No 1 intact, hippie 29 55 3 3 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 Not Cancer Driver No 1 hippie 22 34 6 6 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 Census, Compendium Yes 2 intact, hippie 24 72 5 5 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 Not Cancer Driver No 1 hippie 45 190 19 19 0
C1orf216 C1orf216 Q8TAB5 UPF0500 protein C1orf216 chr1 Not Cancer Driver No 1 intact 22 199 21 21 0
CCDC13 CCDC13 Q8IYE1 Coiled-coil domain-containing protein 13 chr3 Not Cancer Driver No 1 intact, hippie 114 580 95 95 0
CCDC57_ENST00000392347 CCDC57 Q2TAC2 Coiled-coil domain-containing protein 57 chr17 Not Cancer Driver No 1 intact, hippie 107 595 65 65 0
CCDC85A CCDC85A Q96PX6 Coiled-coil domain-containing protein 85A chr2 Not Cancer Driver No 1 hippie, biogrid 146 399 116 116 0
CCDC85B CCDC85B Q15834 Coiled-coil domain-containing protein 85B chr11 Not Cancer Driver No 1 intact, hippie 3 79 2 2 0
CCDC85C CCDC85C A6NKD9 Coiled-coil domain-containing protein 85C chr14 Not Cancer Driver No 1 intact, hippie 5 303 5 5 0
CCDC92 CCDC92 Q53HC0 Coiled-coil domain-containing protein 92 chr12 Not Cancer Driver No 1 hippie 60 299 49 49 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 100 618 77 77 0
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CENPJ CENPJ Q9HC77 Centromere protein J chr13 Not Cancer Driver No 1 intact, hippie 176 1176 158 158 1
CEP104 CEP104 O60308 Centrosomal protein of 104 kDa chr1 Not Cancer Driver No 1 hippie 116 306 43 43 0
CEP120 CEP120 Q8N960 Centrosomal protein of 120 kDa chr5 Not Cancer Driver No 1 hippie 102 448 52 52 1
CEP128_ENST00000281129 CEP128 Q6ZU80 Centrosomal protein of 128 kDa chr14 Not Cancer Driver No 1 hippie 195 897 167 167 0
CEP135 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 Not Cancer Driver No 1 hippie 127 690 72 72 0
CEP152 CEP152 O94986 Centrosomal protein of 152 kDa chr15 Not Cancer Driver No 1 intact, hippie 204 986 110 110 2
CEP162 CEP162 Q5TB80 Centrosomal protein of 162 kDa chr6 Not Cancer Driver No 1 intact, hippie 162 1056 128 128 0
CEP44_ENST00000296519 CEP44 Q9C0F1 Centrosomal protein of 44 kDa chr4 Not Cancer Driver No 1 hippie 55 142 17 17 0
CEP55 CEP55 Q53EZ4 Centrosomal protein of 55 kDa chr10 Not Cancer Driver No 1 hippie 59 264 26 26 0
CEP89 CEP89 Q96ST8 Centrosomal protein of 89 kDa chr19 Census Yes 1 hippie 96 540 72 72 0
CEP95 CEP95 Q96GE4 Centrosomal protein of 95 kDa chr17 Not Cancer Driver No 1 intact, hippie 96 528 61 61 0
CEP97 CEP97 Q8IW35 Centrosomal protein of 97 kDa chr3 Not Cancer Driver No 1 hippie 95 405 41 41 0
CGN CGN Q9P2M7 Cingulin chr1 Not Cancer Driver No 1 intact, hippie 152 1179 149 149 0
CNTRL_ENST00000238341 CNTRL Q7Z7A1 Centriolin chr9 Census Yes 1 hippie 234 1556 159 159 0
CNTROB_ENST00000563694 CNTROB Q8N137 Centrobin chr17 Not Cancer Driver No 1 intact, hippie 97 837 93 93 0
CPVL_ENST00000265394 CPVL Q9H3G5 Probable serine carboxypeptidase CPVL chr7 Not Cancer Driver No 1 intact, hippie 81 0 0 0 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 412 1796 247 247 33
CRELD2_ENST00000328268 CRELD2 Q6UXH1 Protein disulfide isomerase CRELD2 chr22 Not Cancer Driver No 1 intact 39 33 6 6 0
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 20 19 0 0 4
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 Census Yes 1 hippie, biogrid 126 268 35 35 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 2 hippie, biogrid 415 288 301 301 14
CWF19L2 CWF19L2 Q2TBE0 CWF19-like protein 2 chr11 Not Cancer Driver No 1 hippie 119 615 83 83 0
DCUN1D1 DCUN1D1 Q96GG9 DCN1-like protein 1 chr3 Not Cancer Driver No 1 hippie 34 13 0 0 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DDX6 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 Census, Compendium Yes 1 intact, hippie 44 129 7 7 5
DIRAS1_ENST00000585334 DIRAS1 O95057 GTP-binding protein Di-Ras1 chr19 Not Cancer Driver No 1 intact, hippie 38 32 5 5 0
DYNLT1 DYNLT1 P63172 Dynein light chain Tctex-type 1 chr6 Not Cancer Driver No 1 hippie 7 1 0 0 0
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 109 100 14 14 0
EFHC1 EFHC1 Q5JVL4 EF-hand domain-containing protein 1 chr6 Not Cancer Driver No 1 intact, hippie 79 78 15 15 17
ELOA_ENST00000613537 ELOA Q14241 Elongin-A chr1 Not Cancer Driver No 1 intact, hippie 77 652 62 62 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 Not Cancer Driver No 1 hippie, biogrid 125 669 69 69 0
ENTR1 ENTR1 Q96C92 Endosome-associated-trafficking regulator 1 chr9 Not Cancer Driver No 1 hippie 64 267 38 38 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EPS15L1_ENST00000248070 EPS15L1 Q9UBC2 Epidermal growth factor receptor substrate 15-like 1 chr19 Not Cancer Driver No 1 hippie, biogrid 109 603 76 76 0
FAM168A FAM168A Q92567 Protein FAM168A chr11 Not Cancer Driver No 1 hippie, biogrid 17 139 11 11 0
FBF1_ENST00000586717 FBF1 Q8TES7 Fas-binding factor 1 chr17 Not Cancer Driver No 1 hippie 125 1066 116 116 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 intact 152 230 43 43 74
FRMD6 FRMD6 Q96NE9 FERM domain-containing protein 6 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 116 195 36 36 0
GCC1 GCC1 Q96CN9 GRIP and coiled-coil domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie 118 508 69 69 0
GEM GEM P55040 GTP-binding protein GEM chr8 Not Cancer Driver No 1 hippie 64 96 22 22 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 1 intact, hippie 65 288 42 42 62
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 Census, Compendium Yes 1 hippie 206 1015 184 184 0
GOLGA1 GOLGA1 Q92805 Golgin subfamily A member 1 chr9 Not Cancer Driver No 1 intact, hippie 99 582 77 77 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 Not Cancer Driver No 1 intact, hippie 29 319 26 26 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 97 454 60 60 0
HHEX HHEX Q03014 Hematopoietically-expressed homeobox protein HHEX chr10 Not Cancer Driver No 1 hippie 23 193 21 21 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 37 77 9 9 0
HIST1H1C H1-2 P16403 Histone H1.2 chr6 Not Cancer Driver No 1 intact 79 211 78 78 0
HIST1H2BH H2BC9 Q93079 Histone H2B type 1-H chr6 Not Cancer Driver No 1 intact 42 79 20 20 0
HNRNPUL1 HNRNPUL1 Q9BUJ2 Heterogeneous nuclear ribonucleoprotein U-like protein 1 chr19 Not Cancer Driver No 1 hippie 100 535 49 49 0
HOMER1 HOMER1 Q86YM7 Homer protein homolog 1 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 46 243 32 32 0
HSF2BP HSF2BP O75031 Heat shock factor 2-binding protein chr21 Not Cancer Driver No 1 intact, hippie 52 23 3 3 1
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 93 286 38 38 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 intact, hippie 80 351 24 24 0
HSPH1_ENST00000320027 HSPH1 Q92598 Heat shock protein 105 kDa chr13 Not Cancer Driver No 1 intact, hippie 103 323 42 42 0
INSYN2 INSYN2A Q6ZSG2 Inhibitory synaptic factor 2A chr10 Not Cancer Driver No 1 intact 90 393 76 76 0
IQUB_ENST00000324698 IQUB Q8NA54 IQ and ubiquitin-like domain-containing protein chr7 Not Cancer Driver No 1 intact, hippie 152 156 35 35 0
IRS4 IRS4 O14654 Insulin receptor substrate 4 chrX Census, Compendium Yes 1 intact, hippie 297 798 203 203 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 Not Cancer Driver No 1 hippie 95 335 42 42 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 hippie 67 291 28 28 3
KIF5A KIF5A Q12840 Kinesin heavy chain isoform 5A chr12 Not Cancer Driver No 1 hippie, biogrid 194 569 103 103 14
KRT19 KRT19 P08727 Keratin, type I cytoskeletal 19 chr17 Not Cancer Driver No 1 hippie, biogrid 57 165 19 19 0
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 Census, Compendium Yes 1 hippie, biogrid 161 788 100 100 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 hippie, biogrid 178 687 116 116 0
LHX4 LHX4 Q969G2 LIM/homeobox protein Lhx4 chr1 Not Cancer Driver No 1 intact, hippie 75 219 45 45 4
LMNB1 LMNB1 P20700 Lamin-B1 chr5 Not Cancer Driver No 1 intact, hippie 60 404 42 42 4
LMNB2 LMNB2 Q03252 Lamin-B2 chr19 Not Cancer Driver No 1 intact, hippie 67 428 42 42 5
LMO4 LMO4 P61968 LIM domain transcription factor LMO4 chr1 Not Cancer Driver No 1 hippie 30 11 1 1 0
LURAP1 LURAP1 Q96LR2 Leucine rich adaptor protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 30 169 18 18 0
MAGI1 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie 260 1212 220 220 0
MAPK8IP2 MAPK8IP2 Q13387 C-Jun-amino-terminal kinase-interacting protein 2 chr22 Not Cancer Driver No 1 hippie 49 568 27 27 0
MED4 MED4 Q9NPJ6 Mediator of RNA polymerase II transcription subunit 4 chr13 Not Cancer Driver No 1 hippie 29 161 17 17 0
MIB1 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 Not Cancer Driver No 1 hippie 122 282 34 34 1
MOS MOS P00540 Proto-oncogene serine/threonine-protein kinase mos chr8 Not Cancer Driver No 1 intact, hippie 94 16 4 4 0
MPDZ MPDZ O75970 Multiple PDZ domain protein chr9 Not Cancer Driver No 1 hippie, biogrid 287 858 122 122 0
MPP5 PALS1 Q8N3R9 Protein PALS1 chr14 Not Cancer Driver No 1 intact 70 337 33 33 0
MRPL20 MRPL20 Q9BYC9 39S ribosomal protein L20, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie, biogrid 20 0 0 0 0
MTMR14 MTMR14 Q8NCE2 Myotubularin-related protein 14 chr3 Not Cancer Driver No 1 hippie 58 150 8 8 2
MTURN MTURN Q8N3F0 Maturin chr7 Not Cancer Driver No 1 intact, hippie 15 27 6 6 0
MYBPHL MYBPHL A2RUH7 Myosin-binding protein H-like chr1 Not Cancer Driver No 1 intact 36 84 6 6 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NAE1_ENST00000290810 NAE1 Q13564 NEDD8-activating enzyme E1 regulatory subunit chr16 Not Cancer Driver No 1 hippie 39 69 3 3 0
NAP1L2 NAP1L2 Q9ULW6 Nucleosome assembly protein 1-like 2 chrX Not Cancer Driver No 1 intact 124 178 55 55 0
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 Not Cancer Driver No 2 hippie, biogrid 80 313 45 45 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 150 711 79 79 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 hippie 104 344 38 38 0
NHSL2 NHSL2 Q5HYW2 NHS-like protein 2 chrX Not Cancer Driver No 1 intact, hippie 123 1127 119 119 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 239 1392 164 164 2
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 intact, hippie 230 881 150 150 0
NUP153_ENST00000262077 NUP153 P49790 Nuclear pore complex protein Nup153 chr6 Not Cancer Driver No 1 hippie 180 1152 147 147 0
NUTF2_ENST00000569436 NUTF2 P61970 Nuclear transport factor 2 chr16 Not Cancer Driver No 1 hippie 24 6 4 4 0
NUTM1_ENST00000614490 NUTM1 Q86Y26 NUT family member 1 chr15 Census Yes 1 hippie 202 967 175 175 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OCLN OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 54 244 21 21 1
ODF2 ODF2 Q5BJF6 Outer dense fiber protein 2 chr9 Not Cancer Driver No 1 intact, hippie 123 607 90 90 0
OFD1 OFD1 O75665 Oral-facial-digital syndrome 1 protein chrX Not Cancer Driver No 1 hippie 129 476 58 58 5
OTUB2 OTUB2 Q96DC9 Ubiquitin thioesterase OTUB2 chr14 Not Cancer Driver No 1 hippie 30 0 0 0 0
P4HA3_ENST00000331597 P4HA3 Q7Z4N8 Prolyl 4-hydroxylase subunit alpha-3 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 70 17 2 2 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 3 intact, hippie, biogrid 200 1144 170 170 2
PARD6A PARD6A Q9NPB6 Partitioning defective 6 homolog alpha chr16 Not Cancer Driver No 1 intact, hippie 25 177 13 13 0
PARD6B PARD6B Q9BYG5 Partitioning defective 6 homolog beta chr20 Not Cancer Driver No 1 intact, hippie 50 166 23 23 0
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 Census Yes 2 intact, hippie, biogrid 152 1665 134 134 0
PHF1 PHF1 O43189 PHD finger protein 1 chr6 Not Cancer Driver No 1 hippie 62 277 29 29 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 Not Cancer Driver No 1 intact, hippie 83 419 45 45 2
PLEC PLEC Q15149 Plectin chr8 Not Cancer Driver No 1 intact, hippie 677 2130 272 272 2
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHF2 PLEKHF2 Q9H8W4 Pleckstrin homology domain-containing family F member 2 chr8 Not Cancer Driver No 1 hippie 32 36 4 4 0
PLEKHN1 PLEKHN1 Q494U1 Pleckstrin homology domain-containing family N member 1 chr1 Not Cancer Driver No 2 intact, hippie 59 369 37 37 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 87 119 13 13 0
POLR2L POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 Not Cancer Driver No 1 hippie 10 0 0 0 0
PPHLN1_ENST00000610488 PPHLN1 Q8NEY8 Periphilin-1 chr12 Not Cancer Driver No 1 hippie 64 447 62 62 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 10 intact, hippie, biogrid 38 27 6 6 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 4 intact, hippie 47 25 5 5 5
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 12 intact, hippie, biogrid 26 23 4 4 0
PPP1R2 PPP1R2 P41236 Protein phosphatase inhibitor 2 chr3 Not Cancer Driver No 1 intact, hippie 19 205 19 19 0
PPP1R3A PPP1R3A Q16821 Protein phosphatase 1 regulatory subunit 3A chr7 Not Cancer Driver No 1 hippie 430 807 334 334 1
PPP1R7 PPP1R7 Q15435 Protein phosphatase 1 regulatory subunit 7 chr2 Not Cancer Driver No 1 hippie 46 78 16 16 0
PRAM1 PRAM1 Q96QH2 PML-RARA-regulated adapter molecule 1 chr19 Not Cancer Driver No 1 intact, hippie 118 628 117 117 0
PRKAB2 PRKAB2 O43741 5'-AMP-activated protein kinase subunit beta-2 chr1 Not Cancer Driver No 1 intact, hippie 31 110 12 12 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 Not Cancer Driver No 1 hippie 110 120 16 16 0
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 71 109 16 16 0
PRPF31 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 Not Cancer Driver No 1 hippie 58 213 17 17 2
PRPH PRPH P41219 Peripherin chr12 Not Cancer Driver No 1 hippie, biogrid 37 239 20 20 0
PTN PTN P21246 Pleiotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 43 51 11 11 0
PYGO1 PYGO1 Q9Y3Y4 Pygopus homolog 1 chr15 Not Cancer Driver No 1 intact 71 362 60 60 0
RAB3C RAB3C Q96E17 Ras-related protein Rab-3C chr5 Not Cancer Driver No 1 intact 52 54 10 10 0
RALBP1 RALBP1 Q15311 RalA-binding protein 1 chr18 Not Cancer Driver No 1 hippie 65 381 46 46 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 1 hippie 20 14 1 1 0
RASAL3 RASAL3 Q86YV0 RAS protein activator like-3 chr19 Not Cancer Driver No 1 intact, hippie 114 536 68 68 0
RASSF10 RASSF10 A6NK89 Ras association domain-containing protein 10 chr11 Not Cancer Driver No 2 intact, hippie 11 372 8 8 0
RASSF7 RASSF7 Q02833 Ras association domain-containing protein 7 chr11 Not Cancer Driver No 4 intact, hippie, biogrid 28 278 19 19 0
RASSF8_ENST00000541490 RASSF8 Q8NHQ8 Ras association domain-containing protein 8 chr12 Not Cancer Driver No 6 intact, hippie, biogrid 47 206 19 19 0
RASSF9 RASSF9 O75901 Ras association domain-containing protein 9 chr12 Not Cancer Driver No 1 hippie 88 131 24 24 0
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RGMA_ENST00000329082 RGMA Q96B86 Repulsive guidance molecule A chr15 Not Cancer Driver No 1 intact, hippie 63 105 13 13 0
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact 137 417 61 61 0
RPGRIP1 RPGRIP1 Q96KN7 X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 chr14 Not Cancer Driver No 1 intact, hippie 219 680 110 110 6
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 Not Cancer Driver No 1 intact, hippie 177 586 94 94 8
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 Not Cancer Driver No 1 hippie, biogrid 38 150 25 25 0
RXRB_ENST00000374680 RXRB P28702 Retinoic acid receptor RXR-beta chr6 Not Cancer Driver No 1 hippie 61 279 25 25 0
SCLT1 SCLT1 Q96NL6 Sodium channel and clathrin linker 1 chr4 Not Cancer Driver No 1 intact, hippie 98 398 61 61 0
SCNM1 SCNM1 Q9BWG6 Sodium channel modifier 1 chr1 Not Cancer Driver No 1 intact, hippie 31 172 23 23 0
SETD5 SETD5 Q9C0A6 Histone-lysine N-methyltransferase SETD5 chr3 Not Cancer Driver No 1 hippie 208 1130 165 165 1
SGF29 SGF29 Q96ES7 SAGA-associated factor 29 chr16 Not Cancer Driver No 2 intact, hippie 31 131 17 17 0
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 1 intact, hippie 102 530 82 82 0
SH3RF1 SH3RF1 Q7Z6J0 E3 ubiquitin-protein ligase SH3RF1 chr4 Not Cancer Driver No 1 hippie 109 586 72 72 0
SHTN1 SHTN1 A0MZ66 Shootin-1 chr10 Census Yes 1 intact, hippie 68 470 52 52 0
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 Not Cancer Driver No 1 hippie 35 28 2 2 5
SIAH2 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 Not Cancer Driver No 1 hippie 48 68 3 3 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie, biogrid 54 267 32 32 30
SRGAP3 SRGAP3 O43295 SLIT-ROBO Rho GTPase-activating protein 3 chr3 Census, Compendium Yes 3 intact, hippie, biogrid 195 549 97 97 0
SSX2IP SSX2IP Q9Y2D8 Afadin- and alpha-actinin-binding protein chr1 Not Cancer Driver No 2 intact, hippie 82 265 31 31 0
STAM2 STAM2 O75886 Signal transducing adapter molecule 2 chr2 Not Cancer Driver No 1 hippie, biogrid 69 291 30 30 0
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 20 20 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
SYNE3 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 143 236 42 42 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 1 hippie 42 302 26 26 0
TARSL2 TARS3 A2RTX5 Threonine--tRNA ligase 2, cytoplasmic chr15 Not Cancer Driver No 1 intact 90 77 14 14 0
TBC1D22B TBC1D22B Q9NU19 TBC1 domain family member 22B chr6 Not Cancer Driver No 3 intact, hippie 55 205 27 27 0
TCL1A TCL1A P56279 T-cell leukemia/lymphoma protein 1A chr14 Census Yes 1 hippie 30 5 1 1 0
TCTE1 TCTE1 Q5JU00 Dynein regulatory complex subunit 5 chr6 Not Cancer Driver No 1 hippie 101 125 20 20 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 Not Cancer Driver No 1 hippie, biogrid 198 1350 151 151 0
TJP2_ENST00000377245 TJP2 Q9UDY2 Tight junction protein ZO-2 chr9 Not Cancer Driver No 1 hippie, biogrid 149 919 113 113 1
TP53BP2 TP53BP2 Q13625 Apoptosis-stimulating of p53 protein 2 chr1 Not Cancer Driver No 1 intact, hippie 152 868 118 118 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 7 intact, hippie 2891 282 1466 1466 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 Census, Compendium Yes 1 intact, hippie 229 398 143 143 28
TP73 TP73 O15350 Tumor protein p73 chr1 Not Cancer Driver No 1 intact, hippie 82 443 55 55 0
TRAF4 TRAF4 Q9BUZ4 TNF receptor-associated factor 4 chr17 Not Cancer Driver No 1 hippie 42 27 1 1 0
TROAP TROAP Q12815 Tastin chr12 Not Cancer Driver No 1 intact, hippie 105 642 93 93 0
TSGA10_ENST00000355053 TSGA10 Q9BZW7 Testis-specific gene 10 protein chr2 Not Cancer Driver No 1 hippie 112 477 76 76 0
TXLNA_ENST00000373610 TXLNA P40222 Alpha-taxilin chr1 Not Cancer Driver No 2 intact, hippie 68 481 59 59 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 Not Cancer Driver No 1 intact, hippie 148 213 29 29 0
UBASH3A UBASH3A P57075 Ubiquitin-associated and SH3 domain-containing protein A chr21 Not Cancer Driver No 2 intact, hippie 101 27 8 8 0
UBASH3B UBASH3B Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B chr11 Not Cancer Driver No 1 intact, hippie 86 73 6 6 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 Not Cancer Driver No 1 intact, hippie 141 136 22 22 0
UBTD1 UBTD1 Q9HAC8 Ubiquitin domain-containing protein 1 chr10 Not Cancer Driver No 1 intact, hippie 36 125 10 10 0
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 Not Cancer Driver No 1 intact, hippie, biogrid 20 89 4 4 1
USP4 USP4 Q13107 Ubiquitin carboxyl-terminal hydrolase 4 chr3 Not Cancer Driver No 1 hippie, biogrid 102 286 22 22 0
UTP14A UTP14A Q9BVJ6 U3 small nucleolar RNA-associated protein 14 homolog A chrX Not Cancer Driver No 1 hippie, biogrid 105 629 89 89 0
VASP VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 1 hippie, biogrid 39 335 34 34 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WWP1 WWP1 Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 chr8 Not Cancer Driver No 1 hippie 139 431 75 75 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 2 hippie, biogrid 112 422 57 57 0
WWTR1_ENST00000360632 WWTR1 Q9GZV5 WW domain-containing transcription regulator protein 1 chr3 Census Yes 1 hippie 41 387 41 41 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 5 intact, hippie, biogrid 51 489 49 49 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie 65 62 10 10 0
YOD1 YOD1 Q5VVQ6 Ubiquitin thioesterase OTU1 chr1 Not Cancer Driver No 1 intact, hippie 30 120 6 6 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 intact, hippie, biogrid 22 109 4 4 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 3 intact, hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 4 intact, hippie, biogrid 15 55 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 hippie 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 3 intact, hippie 30 81 10 10 0
ZBTB4_ENST00000380599 ZBTB4 Q9P1Z0 Zinc finger and BTB domain-containing protein 4 chr17 Not Cancer Driver No 1 intact, hippie 140 788 109 109 0
ZFP91 ZFP91 Q96JP5 E3 ubiquitin-protein ligase ZFP91 chr11 Not Cancer Driver No 1 hippie 85 383 55 55 0
ZGPAT ZGPAT Q8N5A5 Zinc finger CCCH-type with G patch domain-containing protein chr20 Not Cancer Driver No 3 intact, hippie 75 346 49 49 0
ZNF26 ZNF26 P17031 Zinc finger protein 26 chr12 Not Cancer Driver No 1 hippie 4 60 0 0 0
ZNF438 ZNF438 Q7Z4V0 Zinc finger protein 438 chr10 Not Cancer Driver No 1 intact, hippie 123 612 90 90 0
ZNF552 ZNF552 Q9H707 Zinc finger protein 552 chr19 Not Cancer Driver No 1 intact, hippie 43 99 7 7 0
ZNF575 ZNF575 Q86XF7 Zinc finger protein 575 chr19 Not Cancer Driver No 1 intact, hippie 12 156 9 9 0
ZYX ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie, biogrid 83 385 52 52 0