Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADPGK | ADPGK | Q9BRR6 | ADP-dependent glucokinase | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 24 | 0 | 0 | 0 |
| AGGF1 | AGGF1 | Q8N302 | Angiogenic factor with G patch and FHA domains 1 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 100 | 582 | 80 | 80 | 1 |
| AIFM1 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 88 | 166 | 22 | 22 | 11 |
| AK2 | AK2 | P54819 | Adenylate kinase 2, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 76 | 12 | 12 | 2 |
| AKAP1_ENST00000539273 | AKAP1 | Q92667 | A-kinase anchor protein 1, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 107 | 537 | 67 | 67 | 0 |
| ARF6 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 5 | 0 | 0 | 0 |
| ARHGEF4 | ARHGEF4 | Q9NR80 | Rho guanine nucleotide exchange factor 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 114 | 287 | 61 | 61 | 0 |
| ATG4C_ENST00000371120 | ATG4C | Q96DT6 | Cysteine protease ATG4C | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 17 | 3 | 3 | 0 |
| ATP2A1 | ATP2A1 | O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 80 | 11 | 11 | 1 |
| AXL | AXL | P30530 | Tyrosine-protein kinase receptor UFO | chr19 | Not Cancer Driver | No | 1 | hippie | 168 | 341 | 64 | 64 | 0 |
| B3GAT1_ENST00000312527 | B3GAT1 | Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 93 | 32 | 32 | 0 |
| BCAP31_ENST00000345046 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 104 | 14 | 14 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
| BRWD1 | BRWD1 | Q9NSI6 | Bromodomain and WD repeat-containing protein 1 | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 273 | 1304 | 157 | 157 | 0 |
| CA10_ENST00000285273 | CA10 | Q9NS85 | Carbonic anhydrase-related protein 10 | chr17 | Not Cancer Driver | No | 3 | hippie, biogrid | 103 | 9 | 1 | 1 | 0 |
| CA9 | CA9 | Q16790 | Carbonic anhydrase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 72 | 274 | 50 | 50 | 0 |
| CALR3 | CALR3 | Q96L12 | Calreticulin-3 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 101 | 16 | 16 | 0 |
| CALU_ENST00000249364 | CALU | O43852 | Calumenin | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 130 | 12 | 12 | 0 |
| CANX_ENST00000504734 | CANX | P27824 | Calnexin | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 65 | 334 | 38 | 38 | 0 |
| CBX3_ENST00000396386 | CBX3 | Q13185 | Chromobox protein homolog 3 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 119 | 18 | 18 | 0 |
| CCDC8 | CCDC8 | Q9H0W5 | Coiled-coil domain-containing protein 8 | chr19 | Not Cancer Driver | No | 1 | hippie | 96 | 505 | 91 | 91 | 0 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
| CENPA | CENPA | P49450 | Histone H3-like centromeric protein A | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 50 | 4 | 4 | 0 |
| CEP135 | CEP135 | Q66GS9 | Centrosomal protein of 135 kDa | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 127 | 690 | 72 | 72 | 0 |
| CHCHD3 | CHCHD3 | Q9NX63 | MICOS complex subunit MIC19 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 26 | 143 | 16 | 16 | 0 |
| CHCHD4_ENST00000396914 | CHCHD4 | Q8N4Q1 | Mitochondrial intermembrane space import and assembly protein 40 | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 18 | 82 | 8 | 8 | 0 |
| CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
| CKAP4 | CKAP4 | Q07065 | Cytoskeleton-associated protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 409 | 55 | 55 | 0 |
| CLGN_ENST00000414773 | CLGN | O14967 | Calmegin | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 255 | 36 | 36 | 0 |
| COPS7A_ENST00000534947 | COPS7A | Q9UBW8 | COP9 signalosome complex subunit 7a | chr12 | Not Cancer Driver | No | 1 | hippie | 32 | 74 | 10 | 10 | 0 |
| CTSB | CTSB | P07858 | Cathepsin B | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 7 | 2 | 2 | 0 |
| CTSS | CTSS | P25774 | Cathepsin S | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 0 | 0 | 0 | 0 |
| CUL4B | CUL4B | Q13620 | Cullin-4B | chrX | Not Cancer Driver | No | 1 | hippie | 138 | 207 | 38 | 38 | 2 |
| CXADR | CXADR | P78310 | Coxsackievirus and adenovirus receptor | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 98 | 19 | 19 | 0 |
| CYP2C9 | CYP2C9 | P11712 | Cytochrome P450 2C9 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 122 | 36 | 14 | 14 | 0 |
| DERL1 | DERL1 | Q9BUN8 | Derlin-1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 11 | 1 | 1 | 0 |
| DHFR2_ENST00000314636 | DHFR2 | Q86XF0 | Dihydrofolate reductase 2, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 25 | 20 | 0 | 0 | 0 |
| DIRAS3_ENST00000646789 | DIRAS3 | O95661 | GTP-binding protein Di-Ras3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 21 | 3 | 3 | 0 |
| DNAJB11_ENST00000265028 | DNAJB11 | Q9UBS4 | DnaJ homolog subfamily B member 11 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 141 | 21 | 21 | 2 |
| DNAJB6 | DNAJB6 | O75190 | DnaJ homolog subfamily B member 6 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 198 | 17 | 17 | 3 |
| DNAJC1 | DNAJC1 | Q96KC8 | DnaJ homolog subfamily C member 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 315 | 44 | 44 | 0 |
| DNAJC16 | DNAJC16 | Q9Y2G8 | DnaJ homolog subfamily C member 16 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 63 | 2 | 2 | 0 |
| DNAJC22_ENST00000395069 | DNAJC22 | Q8N4W6 | DnaJ homolog subfamily C member 22 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 11 | 1 | 1 | 0 |
| DNAJC25 | DNAJC25 | Q9H1X3 | DnaJ homolog subfamily C member 25 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 39 | 3 | 3 | 0 |
| DNAJC3 | DNAJC3 | Q13217 | DnaJ homolog subfamily C member 3 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 131 | 17 | 17 | 0 |
| DPP4 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 151 | 8 | 1 | 1 | 0 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
| EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
| EIF4G1_ENST00000346169 | EIF4G1 | Q04637 | Eukaryotic translation initiation factor 4 gamma 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 229 | 1079 | 153 | 153 | 2 |
| ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 69 | 43 | 5 | 5 | 0 |
| ELOVL5_ENST00000304434 | ELOVL5 | Q9NYP7 | Elongation of very long chain fatty acids protein 5 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 25 | 4 | 4 | 2 |
| EMC1 | EMC1 | Q8N766 | ER membrane protein complex subunit 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 107 | 59 | 6 | 6 | 2 |
| EMD | EMD | P50402 | Emerin | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 160 | 28 | 28 | 4 |
| EPHA10 | EPHA10 | Q5JZY3 | Ephrin type-A receptor 10 | chr1 | Not Cancer Driver | No | 1 | intact | 171 | 225 | 41 | 41 | 0 |
| EPHA8 | EPHA8 | P29322 | Ephrin type-A receptor 8 | chr1 | Not Cancer Driver | No | 1 | intact | 197 | 121 | 17 | 17 | 0 |
| ERGIC1 | ERGIC1 | Q969X5 | Endoplasmic reticulum-Golgi intermediate compartment protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 26 | 2 | 2 | 0 |
| ERGIC2 | ERGIC2 | Q96RQ1 | Endoplasmic reticulum-Golgi intermediate compartment protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 25 | 2 | 2 | 0 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
| ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
| EVC2 | EVC2 | Q86UK5 | Limbin | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 240 | 335 | 71 | 71 | 2 |
| FAM160B1 | FHIP2A | Q5W0V3 | FHF complex subunit HOOK interacting protein 2A | chr10 | Not Cancer Driver | No | 1 | intact | 92 | 130 | 13 | 13 | 0 |
| FBXO2 | FBXO2 | Q9UK22 | F-box only protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 75 | 1 | 1 | 0 |
| FKBP8_ENST00000222308 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 160 | 25 | 25 | 0 |
| GJA1 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 110 | 26 | 26 | 50 |
| GJD3 | GJD3 | Q8N144 | Gap junction delta-3 protein | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 79 | 0 | 0 | 0 |
| GLT8D1_ENST00000478968 | GLT8D1 | Q68CQ7 | Glycosyltransferase 8 domain-containing protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 10 | 1 | 1 | 0 |
| GPX8 | GPX8 | Q8TED1 | Probable glutathione peroxidase 8 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 4 | 1 | 1 | 0 |
| GTF2IRD1_ENST00000265755 | GTF2IRD1 | Q9UHL9 | General transcription factor II-I repeat domain-containing protein 1 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 136 | 378 | 56 | 56 | 0 |
| GXYLT1 | GXYLT1 | Q4G148 | Glucoside xylosyltransferase 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 7 | 0 | 0 | 0 |
| HNRNPM | HNRNPM | P52272 | Heterogeneous nuclear ribonucleoprotein M | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 463 | 67 | 67 | 0 |
| HPDL | HPDL | Q96IR7 | 4-hydroxyphenylpyruvate dioxygenase-like protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 58 | 11 | 11 | 2 |
| HRAS | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | intact, hippie | 107 | 16 | 4 | 4 | 18 |
| HSCB | HSCB | Q8IWL3 | Iron-sulfur cluster co-chaperone protein HscB | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 25 | 6 | 6 | 0 |
| HSD17B11 | HSD17B11 | Q8NBQ5 | Estradiol 17-beta-dehydrogenase 11 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 3 | 0 | 0 | 0 |
| HSD3B7 | HSD3B7 | Q9H2F3 | 3 beta-hydroxysteroid dehydrogenase type 7 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 27 | 5 | 5 | 2 |
| HSPA13 | HSPA13 | P48723 | Heat shock 70 kDa protein 13 | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 48 | 7 | 7 | 0 |
| HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 282 | 35 | 35 | 0 |
| IFI16_ENST00000295809 | IFI16 | Q16666 | Gamma-interferon-inducible protein 16 | chr1 | Not Cancer Driver | No | 1 | hippie | 155 | 419 | 90 | 90 | 0 |
| INS | INS | P01308 | Insulin | chr11 | Not Cancer Driver | No | 1 | hippie | 15 | 5 | 1 | 1 | 22 |
| INSR | INSR | P06213 | Insulin receptor | chr19 | Not Cancer Driver | No | 1 | intact | 190 | 280 | 57 | 57 | 64 |
| IPO4 | IPO4 | Q8TEX9 | Importin-4 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 106 | 87 | 5 | 5 | 0 |
| KLHL15 | KLHL15 | Q96M94 | Kelch-like protein 15 | chrX | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 74 | 25 | 4 | 4 | 0 |
| KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 2 | intact, hippie, biogrid | 788 | 7 | 2 | 2 | 27 |
| LAMP1 | LAMP1 | P11279 | Lysosome-associated membrane glycoprotein 1 | chr13 | Not Cancer Driver | No | 2 | hippie, biogrid | 47 | 93 | 10 | 10 | 0 |
| LAMP2_ENST00000200639 | LAMP2 | P13473 | Lysosome-associated membrane glycoprotein 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 55 | 7 | 7 | 1 |
| LAMP3 | LAMP3 | Q9UQV4 | Lysosome-associated membrane glycoprotein 3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 222 | 38 | 38 | 0 |
| LMAN1 | LMAN1 | P49257 | Protein ERGIC-53 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 222 | 25 | 25 | 1 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
| LMNA | LMNA | P02545 | Prelamin-A/C | chr1 | Census | Yes | 3 | intact, hippie, biogrid | 68 | 544 | 49 | 49 | 131 |
| LMNB1 | LMNB1 | P20700 | Lamin-B1 | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 60 | 404 | 42 | 42 | 4 |
| LNPK_ENST00000272748 | LNPK | Q9C0E8 | Endoplasmic reticulum junction formation protein lunapark | chr2 | Not Cancer Driver | No | 1 | hippie | 62 | 257 | 43 | 43 | 0 |
| LRRC59 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 122 | 15 | 15 | 0 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 2 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
| MAD2L1 | MAD2L1 | Q13257 | Mitotic spindle assembly checkpoint protein MAD2A | chr4 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 26 | 12 | 1 | 1 | 0 |
| MAD2L1BP_ENST00000372171 | MAD2L1BP | Q15013 | MAD2L1-binding protein | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 26 | 55 | 7 | 7 | 0 |
| MAGT1_ENST00000618282 | MAGT1 | Q9H0U3 | Magnesium transporter protein 1 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 0 | 0 | 0 | 1 |
| MAP2K1 | MAP2K1 | Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | chr15 | Census, Compendium | Yes | 1 | hippie | 94 | 96 | 24 | 24 | 6 |
| MAPK6 | MAPK6 | Q16659 | Mitogen-activated protein kinase 6 | chr15 | Not Cancer Driver | No | 1 | hippie | 79 | 165 | 20 | 20 | 0 |
| MARCKS | MARCKS | P29966 | Myristoylated alanine-rich C-kinase substrate | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 328 | 14 | 14 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | hippie | 56 | 297 | 37 | 37 | 0 |
| METTL7A_ENST00000332160 | METTL7A | Q9H8H3 | Putative methyltransferase-like protein 7A | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 0 | 0 | 0 | 0 |
| MREG | MREG | Q8N565 | Melanoregulin | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 21 | 24 | 2 | 2 | 0 |
| NAA40 | NAA40 | Q86UY6 | N-alpha-acetyltransferase 40 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 30 | 3 | 3 | 0 |
| NARF | NARF | Q9UHQ1 | Nuclear prelamin A recognition factor | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 62 | 75 | 11 | 11 | 0 |
| NCAPD3 | NCAPD3 | P42695 | Condensin-2 complex subunit D3 | chr11 | Not Cancer Driver | No | 1 | hippie | 193 | 304 | 42 | 42 | 1 |
| NDUFV1 | NDUFV1 | P49821 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 57 | 9 | 9 | 3 |
| NIT2 | NIT2 | Q9NQR4 | Omega-amidase NIT2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 0 | 0 | 0 | 0 |
| NRAS | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 284 | 10 | 0 | 0 | 14 |
| NSD2_ENST00000382892 | NSD2 | O96028 | Histone-lysine N-methyltransferase NSD2 | chr4 | Census, Compendium | Yes | 1 | hippie | 191 | 552 | 76 | 76 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
| NTRK3_ENST00000629765 | NTRK3 | Q16288 | NT-3 growth factor receptor | chr15 | Census, Compendium | Yes | 1 | intact | 249 | 57 | 21 | 21 | 0 |
| NUP155 | NUP155 | O75694 | Nuclear pore complex protein Nup155 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 154 | 221 | 19 | 19 | 1 |
| NUP50 | NUP50 | Q9UKX7 | Nuclear pore complex protein Nup50 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 333 | 40 | 40 | 0 |
| OGT | OGT | O15294 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | chrX | Not Cancer Driver | No | 1 | hippie | 156 | 89 | 16 | 16 | 2 |
| OTULINL | OTULINL | Q9NUU6 | Inactive ubiquitin thioesterase OTULINL | chr5 | Not Cancer Driver | No | 1 | hippie | 59 | 21 | 0 | 0 | 0 |
| OXCT1 | OXCT1 | P55809 | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 39 | 5 | 5 | 11 |
| PANX1 | PANX1 | Q96RD7 | Pannexin-1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 45 | 7 | 7 | 2 |
| PDE3A | PDE3A | Q14432 | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 274 | 527 | 114 | 114 | 6 |
| PDIA4 | PDIA4 | P13667 | Protein disulfide-isomerase A4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 147 | 22 | 22 | 0 |
| PDIA5 | PDIA5 | Q14554 | Protein disulfide-isomerase A5 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 79 | 9 | 9 | 0 |
| PEAK1_ENST00000312493 | PEAK1 | Q9H792 | Inactive tyrosine-protein kinase PEAK1 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 222 | 1232 | 150 | 150 | 0 |
| PIGT | PIGT | Q969N2 | GPI transamidase component PIG-T | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 51 | 36 | 6 | 6 | 1 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PPM1A_ENST00000395076 | PPM1A | P35813 | Protein phosphatase 1A | chr14 | Not Cancer Driver | No | 1 | hippie | 60 | 134 | 24 | 24 | 0 |
| PPP1CA_ENST00000376745 | PPP1CA | P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | chr11 | Not Cancer Driver | No | 3 | intact, hippie | 38 | 27 | 6 | 6 | 0 |
| PPP1CC_ENST00000335007 | PPP1CC | P36873 | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | chr12 | Not Cancer Driver | No | 2 | intact, hippie | 26 | 23 | 4 | 4 | 0 |
| PRKACA | PRKACA | P17612 | cAMP-dependent protein kinase catalytic subunit alpha | chr19 | Census | Yes | 1 | hippie, biogrid | 53 | 24 | 0 | 0 | 2 |
| PSME1_ENST00000206451 | PSME1 | Q06323 | Proteasome activator complex subunit 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 20 | 80 | 8 | 8 | 0 |
| PTCH1 | PTCH1 | Q13635 | Protein patched homolog 1 | chr9 | Census, Compendium | Yes | 1 | hippie, biogrid | 243 | 382 | 67 | 67 | 18 |
| PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 140 | 25 | 25 | 0 |
| PXMP2 | PXMP2 | Q9NR77 | Peroxisomal membrane protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 0 | 0 | 0 | 0 |
| RAB11A | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 43 | 4 | 4 | 0 |
| RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 25 | 2 | 2 | 0 |
| RAB3B | RAB3B | P20337 | Ras-related protein Rab-3B | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 25 | 6 | 6 | 0 |
| RAB4A | RAB4A | P20338 | Ras-related protein Rab-4A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 32 | 11 | 11 | 0 |
| RAB5A | RAB5A | P20339 | Ras-related protein Rab-5A | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 65 | 15 | 15 | 0 |
| RAB5C_ENST00000393860 | RAB5C | P51148 | Ras-related protein Rab-5C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 50 | 4 | 4 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 1 | biogrid | 27 | 11 | 0 | 0 | 4 |
| RAB9A | RAB9A | P51151 | Ras-related protein Rab-9A | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 21 | 1 | 1 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
| RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
| RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 4 |
| REEP5 | REEP5 | Q00765 | Receptor expression-enhancing protein 5 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 0 | 0 | 0 | 0 |
| RET | RET | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | chr10 | Census, Compendium | Yes | 1 | intact | 208 | 105 | 12 | 12 | 139 |
| RHBDD1 | RHBDD1 | Q8TEB9 | Rhomboid-related protein 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 38 | 69 | 9 | 9 | 0 |
| RHBDF2 | RHBDF2 | Q6PJF5 | Inactive rhomboid protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 93 | 284 | 36 | 36 | 2 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
| RHOC_ENST00000369642 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 53 | 7 | 7 | 0 |
| RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 10 | 0 | 0 | 0 |
| RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
| RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
| RHOJ | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
| RHOT2 | RHOT2 | Q8IXI1 | Mitochondrial Rho GTPase 2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 79 | 5 | 5 | 0 |
| RIF1 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 287 | 1355 | 164 | 164 | 0 |
| RMDN3 | RMDN3 | Q96TC7 | Regulator of microtubule dynamics protein 3 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 196 | 17 | 17 | 0 |
| RND2 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | Not Cancer Driver | No | 1 | hippie | 19 | 54 | 4 | 4 | 0 |
| RPN1 | RPN1 | P04843 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | chr3 | Census | Yes | 1 | hippie, biogrid | 50 | 69 | 3 | 3 | 0 |
| RPN2 | RPN2 | P04844 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 26 | 4 | 4 | 0 |
| S100A16_ENST00000368703 | S100A16 | Q96FQ6 | Protein S100-A16 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 21 | 1 | 1 | 0 |
| SEC61B | SEC61B | P60468 | Protein transport protein Sec61 subunit beta | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 11 | 60 | 7 | 7 | 0 |
| SEC62 | SEC62 | Q99442 | Translocation protein SEC62 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 211 | 23 | 23 | 0 |
| SEC63 | SEC63 | Q9UGP8 | Translocation protein SEC63 homolog | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 98 | 266 | 37 | 37 | 0 |
| SLC25A46 | SLC25A46 | Q96AG3 | Mitochondrial outer membrane protein SLC25A46 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 96 | 2 | 2 | 4 |
| SLFN11_ENST00000308377 | SLFN11 | Q7Z7L1 | Schlafen family member 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 177 | 34 | 8 | 8 | 0 |
| SNW1_ENST00000261531 | SNW1 | Q13573 | SNW domain-containing protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 62 | 488 | 56 | 56 | 0 |
| SPATS1 | SPATS1 | Q496A3 | Spermatogenesis-associated serine-rich protein 1 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 39 | 154 | 18 | 18 | 0 |
| SSR1 | SSR1 | P43307 | Translocon-associated protein subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 114 | 10 | 10 | 0 |
| ST7 | ST7 | Q9NRC1 | Suppressor of tumorigenicity 7 protein | chr7 | Not Cancer Driver | No | 1 | hippie | 62 | 64 | 5 | 5 | 0 |
| STIM1_ENST00000300737 | STIM1 | Q13586 | Stromal interaction molecule 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 387 | 45 | 45 | 13 |
| STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 152 | 20 | 20 | 0 |
| STX6 | STX6 | O43752 | Syntaxin-6 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 78 | 11 | 11 | 0 |
| STX7 | STX7 | O15400 | Syntaxin-7 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 164 | 14 | 14 | 0 |
| SYNCRIP | SYNCRIP | O60506 | Heterogeneous nuclear ribonucleoprotein Q | chr6 | Not Cancer Driver | No | 1 | hippie | 93 | 285 | 39 | 39 | 0 |
| SYNE3 | SYNE3 | Q6ZMZ3 | Nesprin-3 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 143 | 236 | 42 | 42 | 0 |
| SYVN1 | SYVN1 | Q86TM6 | E3 ubiquitin-protein ligase synoviolin | chr11 | Not Cancer Driver | No | 1 | hippie | 63 | 284 | 32 | 32 | 0 |
| TCTN1_ENST00000551590 | TCTN1 | Q2MV58 | Tectonic-1 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 63 | 47 | 6 | 6 | 0 |
| TCTN2 | TCTN2 | Q96GX1 | Tectonic-2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 75 | 23 | 2 | 2 | 0 |
| TCTN3 | TCTN3 | Q6NUS6 | Tectonic-3 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 45 | 71 | 8 | 8 | 1 |
| TERF2 | TERF2 | Q15554 | Telomeric repeat-binding factor 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 33 | 361 | 20 | 20 | 0 |
| TERF2IP | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 28 | 310 | 16 | 16 | 0 |
| TGOLN2_ENST00000377386 | TGOLN2 | O43493 | Trans-Golgi network integral membrane protein 2 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 51 | 399 | 46 | 46 | 0 |
| TMEM106B | TMEM106B | Q9NUM4 | Transmembrane protein 106B | chr7 | Not Cancer Driver | No | 1 | hippie | 31 | 56 | 4 | 4 | 1 |
| TMEM17 | TMEM17 | Q86X19 | Transmembrane protein 17 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 22 | 14 | 2 | 2 | 0 |
| TMEM216 | TMEM216 | Q9P0N5 | Transmembrane protein 216 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 11 | 0 | 0 | 0 | 7 |
| TMEM237 | TMEM237 | Q96Q45 | Transmembrane protein 237 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 47 | 177 | 19 | 19 | 0 |
| TMEM67 | TMEM67 | Q5HYA8 | Meckelin | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 120 | 11 | 0 | 0 | 37 |
| TMPO | TMPO | P42166 | Lamina-associated polypeptide 2, isoform alpha | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 412 | 52 | 52 | 0 |
| TOR1A | TOR1A | O14656 | Torsin-1A | chr9 | Not Cancer Driver | No | 2 | intact, hippie | 33 | 0 | 0 | 0 | 3 |
| TOR1B | TOR1B | O14657 | Torsin-1B | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 0 | 0 | 0 | 0 |
| TOR2A_ENST00000336067 | TOR2A | Q8N2E6 | Prosalusin | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 14 | 34 | 5 | 5 | 0 |
| TOR3A | TOR3A | Q9H497 | Torsin-3A | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 15 | 0 | 0 | 0 |
| TUBB2A | TUBB2A | Q13885 | Tubulin beta-2A chain | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 70 | 13 | 13 | 2 |
| TXN | TXN | P10599 | Thioredoxin | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 6 | 0 | 0 | 0 | 0 |
| UBQLN2 | UBQLN2 | Q9UHD9 | Ubiquilin-2 | chrX | Not Cancer Driver | No | 1 | hippie | 82 | 581 | 79 | 79 | 8 |
| USP1_ENST00000371146 | USP1 | O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 63 | 403 | 30 | 30 | 0 |
| VAPA_ENST00000400000 | VAPA | Q9P0L0 | Vesicle-associated membrane protein-associated protein A | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 184 | 14 | 14 | 0 |
| VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
| ZNF296 | ZNF296 | Q8WUU4 | Zinc finger protein 296 | chr19 | Not Cancer Driver | No | 1 | hippie | 47 | 342 | 36 | 36 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|