Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCC2 | ABCC2 | Q92887 | ATP-binding cassette sub-family C member 2 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 202 | 102 | 23 | 23 | 4 |
| ABCD3 | ABCD3 | P28288 | ATP-binding cassette sub-family D member 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 75 | 21 | 2 | 2 | 0 |
| ABCE1 | ABCE1 | P61221 | ATP-binding cassette sub-family E member 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 74 | 36 | 6 | 6 | 0 |
| ABR | ABR | Q12979 | Active breakpoint cluster region-related protein | chr17 | Not Cancer Driver | No | 1 | hippie | 122 | 184 | 36 | 36 | 0 |
| ACBD3 | ACBD3 | Q9H3P7 | Golgi resident protein GCP60 | chr1 | Not Cancer Driver | No | 1 | hippie | 59 | 350 | 40 | 40 | 0 |
| ACBD5_ENST00000375888 | ACBD5 | Q5T8D3 | Acyl-CoA-binding domain-containing protein 5 | chr10 | Not Cancer Driver | No | 1 | hippie | 65 | 330 | 45 | 45 | 0 |
| ACTR5 | ACTR5 | Q9H9F9 | Actin-related protein 5 | chr20 | Not Cancer Driver | No | 1 | hippie | 63 | 163 | 23 | 23 | 0 |
| AFG3L2 | AFG3L2 | Q9Y4W6 | AFG3-like protein 2 | chr18 | Not Cancer Driver | No | 1 | hippie | 72 | 162 | 10 | 10 | 22 |
| AGO2 | AGO2 | Q9UKV8 | Protein argonaute-2 | chr8 | Not Cancer Driver | No | 1 | hippie | 126 | 141 | 15 | 15 | 11 |
| AGO3 | AGO3 | Q9H9G7 | Protein argonaute-3 | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 143 | 19 | 19 | 0 |
| AIP | AIP | O00170 | AH receptor-interacting protein | chr11 | Not Cancer Driver | No | 1 | hippie | 32 | 64 | 9 | 9 | 1 |
| AKAP1_ENST00000539273 | AKAP1 | Q92667 | A-kinase anchor protein 1, mitochondrial | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 107 | 537 | 67 | 67 | 0 |
| ALDH3A2_ENST00000579855 | ALDH3A2 | P51648 | Aldehyde dehydrogenase family 3 member A2 | chr17 | Not Cancer Driver | No | 1 | hippie | 47 | 5 | 2 | 2 | 26 |
| APC | APC | P25054 | Adenomatous polyposis coli protein | chr5 | Census, Compendium | Yes | 1 | hippie | 412 | 2406 | 345 | 345 | 22 |
| APOA1_ENST00000375320 | APOA1 | P02647 | Apolipoprotein A-I | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 131 | 8 | 8 | 3 |
| ARMCX3_ENST00000537169 | ARMCX3 | Q9UH62 | Armadillo repeat-containing X-linked protein 3 | chrX | Not Cancer Driver | No | 1 | hippie | 39 | 77 | 7 | 7 | 0 |
| ATG16L1 | ATG16L1 | Q676U5 | Autophagy-related protein 16-1 | chr2 | Not Cancer Driver | No | 1 | hippie | 79 | 239 | 25 | 25 | 1 |
| ATP5F1C | ATP5F1C | P36542 | ATP synthase subunit gamma, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie | 39 | 11 | 0 | 0 | 0 |
| ATP5PB | ATP5PB | P24539 | ATP synthase F(0) complex subunit B1, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 37 | 2 | 0 | 0 | 0 |
| ATP5PD | ATP5PD | O75947 | ATP synthase subunit d, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie | 12 | 15 | 0 | 0 | 0 |
| ATP5PF_ENST00000400090 | ATP5PF | P18859 | ATP synthase-coupling factor 6, mitochondrial | chr21 | Not Cancer Driver | No | 1 | hippie | 14 | 15 | 1 | 1 | 0 |
| ATP5PO | ATP5PO | P48047 | ATP synthase subunit O, mitochondrial | chr21 | Not Cancer Driver | No | 1 | hippie | 19 | 9 | 2 | 2 | 0 |
| ATPAF1_ENST00000574428 | ATPAF1 | Q5TC12 | ATP synthase mitochondrial F1 complex assembly factor 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 33 | 47 | 8 | 8 | 0 |
| ATXN1 | ATXN1 | P54253 | Ataxin-1 | chr6 | Not Cancer Driver | No | 1 | hippie | 193 | 604 | 168 | 168 | 0 |
| BAG6 | BAG6 | P46379 | Large proline-rich protein BAG6 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 98 | 861 | 79 | 79 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | Census | Yes | 1 | hippie | 30 | 39 | 2 | 2 | 0 |
| BCL2L11 | BCL2L11 | O43521 | Bcl-2-like protein 11 | chr2 | Not Cancer Driver | No | 1 | hippie | 42 | 130 | 17 | 17 | 0 |
| BCL2L13_ENST00000317582 | BCL2L13 | Q9BXK5 | Bcl-2-like protein 13 | chr22 | Not Cancer Driver | No | 1 | hippie | 49 | 291 | 30 | 30 | 0 |
| BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | Census, Compendium | Yes | 1 | hippie | 24 | 72 | 5 | 5 | 0 |
| BIRC2 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 69 | 83 | 9 | 9 | 0 |
| BPHL | BPHL | Q86WA6 | Valacyclovir hydrolase | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 12 | 1 | 1 | 0 |
| BTF3 | BTF3 | P20290 | Transcription factor BTF3 | chr5 | Not Cancer Driver | No | 1 | hippie | 27 | 192 | 24 | 24 | 0 |
| C1orf198 | C1orf198 | Q9H425 | Uncharacterized protein C1orf198 | chr1 | Not Cancer Driver | No | 1 | hippie | 40 | 303 | 36 | 36 | 0 |
| C9orf72 | C9orf72 | Q96LT7 | Guanine nucleotide exchange factor C9orf72 | chr9 | Not Cancer Driver | No | 1 | hippie | 64 | 11 | 0 | 0 | 0 |
| CANX_ENST00000504734 | CANX | P27824 | Calnexin | chr5 | Not Cancer Driver | No | 1 | hippie | 65 | 334 | 38 | 38 | 0 |
| CCNF | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 221 | 23 | 23 | 3 |
| CDC23 | CDC23 | Q9UJX2 | Cell division cycle protein 23 homolog | chr5 | Not Cancer Driver | No | 1 | hippie | 57 | 45 | 6 | 6 | 0 |
| CDC73 | CDC73 | Q6P1J9 | Parafibromin | chr1 | Census, Compendium | Yes | 1 | hippie | 110 | 210 | 39 | 39 | 2 |
| CDCA3 | CDCA3 | Q99618 | Cell division cycle-associated protein 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 26 | 268 | 26 | 26 | 0 |
| CEP126 | CEP126 | Q9P2H0 | Centrosomal protein of 126 kDa | chr11 | Not Cancer Driver | No | 1 | hippie | 197 | 840 | 151 | 151 | 0 |
| CHCHD3 | CHCHD3 | Q9NX63 | MICOS complex subunit MIC19 | chr7 | Not Cancer Driver | No | 1 | hippie | 26 | 143 | 16 | 16 | 0 |
| CISD1 | CISD1 | Q9NZ45 | CDGSH iron-sulfur domain-containing protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 6 | 18 | 0 | 0 | 0 |
| CRYBG3 | CRYBG3 | Q68DQ2 | Very large A-kinase anchor protein | chr3 | Not Cancer Driver | No | 1 | hippie | 179 | 1770 | 71 | 71 | 0 |
| CUL2_ENST00000374748 | CUL2 | Q13617 | Cullin-2 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 87 | 66 | 3 | 3 | 0 |
| CUL4B | CUL4B | Q13620 | Cullin-4B | chrX | Not Cancer Driver | No | 1 | hippie | 138 | 207 | 38 | 38 | 2 |
| CYB5B | CYB5B | O43169 | Cytochrome b5 type B | chr16 | Not Cancer Driver | No | 1 | hippie | 17 | 58 | 2 | 2 | 0 |
| CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | Census, Compendium | Yes | 1 | hippie | 116 | 213 | 31 | 31 | 3 |
| DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 34 | 181 | 23 | 23 | 0 |
| DDX58 | DDX58 | O95786 | Antiviral innate immune response receptor RIG-I | chr9 | Not Cancer Driver | No | 1 | hippie | 118 | 61 | 10 | 10 | 2 |
| DHFR | DHFR | P00374 | Dihydrofolate reductase | chr5 | Not Cancer Driver | No | 1 | hippie | 16 | 12 | 2 | 2 | 2 |
| DNM1L_ENST00000549701 | DNM1L | O00429 | Dynamin-1-like protein | chr12 | Not Cancer Driver | No | 1 | hippie | 67 | 212 | 23 | 23 | 7 |
| DST_ENST00000370788 | DST | Q03001-14 | Isoform 9 of Dystonin | chr6 | Not Cancer Driver | No | 1 | hippie | 729 | 1895 | 241 | 241 | 0 |
| DTX1 | DTX1 | Q86Y01 | E3 ubiquitin-protein ligase DTX1 | chr12 | Compendium | Yes | 1 | hippie | 107 | 304 | 43 | 43 | 0 |
| DVL1 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 73 | 434 | 38 | 38 | 0 |
| DYNLL1_ENST00000242577 | DYNLL1 | P63167 | Dynein light chain 1, cytoplasmic | chr12 | Not Cancer Driver | No | 1 | hippie | 9 | 0 | 0 | 0 | 0 |
| ECH1 | ECH1 | Q13011 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 35 | 23 | 2 | 2 | 0 |
| EHBP1 | EHBP1 | Q8NDI1 | EH domain-binding protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 148 | 914 | 115 | 115 | 0 |
| EIF2S2 | EIF2S2 | P20042 | Eukaryotic translation initiation factor 2 subunit 2 | chr20 | Not Cancer Driver | No | 1 | hippie | 37 | 185 | 12 | 12 | 0 |
| EIF4ENIF1 | EIF4ENIF1 | Q9NRA8 | Eukaryotic translation initiation factor 4E transporter | chr22 | Not Cancer Driver | No | 1 | hippie | 116 | 899 | 101 | 101 | 0 |
| ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 69 | 43 | 5 | 5 | 0 |
| ETFA | ETFA | P13804 | Electron transfer flavoprotein subunit alpha, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie | 30 | 34 | 2 | 2 | 3 |
| EXD2 | EXD2 | Q9NVH0 | Exonuclease 3'-5' domain-containing protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie | 58 | 176 | 15 | 15 | 0 |
| FAF2 | FAF2 | Q96CS3 | FAS-associated factor 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 54 | 171 | 16 | 16 | 0 |
| FAM107A_ENST00000394481 | FAM107A | O95990 | Actin-associated protein FAM107A | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 141 | 24 | 24 | 0 |
| FAM83B | FAM83B | Q5T0W9 | Protein FAM83B | chr6 | Not Cancer Driver | No | 1 | hippie | 314 | 684 | 219 | 219 | 0 |
| FBXO7 | FBXO7 | Q9Y3I1 | F-box only protein 7 | chr22 | Not Cancer Driver | No | 1 | hippie | 75 | 243 | 38 | 38 | 1 |
| FEM1B | FEM1B | Q9UK73 | Protein fem-1 homolog B | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 33 | 3 | 3 | 0 |
| FEZ1 | FEZ1 | Q99689 | Fasciculation and elongation protein zeta-1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 277 | 49 | 49 | 0 |
| FKBP8_ENST00000222308 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | Not Cancer Driver | No | 1 | hippie | 71 | 160 | 25 | 25 | 0 |
| FOXRED1 | FOXRED1 | Q96CU9 | FAD-dependent oxidoreductase domain-containing protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 66 | 62 | 11 | 11 | 2 |
| GK | GK | P32189 | Glycerol kinase | chrX | Not Cancer Driver | No | 1 | hippie | 85 | 15 | 3 | 3 | 3 |
| GLI3 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | Not Cancer Driver | No | 1 | hippie | 385 | 1352 | 327 | 327 | 7 |
| GOLGA3_ENST00000450791 | GOLGA3 | Q08378 | Golgin subfamily A member 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 221 | 1272 | 189 | 189 | 0 |
| GPATCH1 | GPATCH1 | Q9BRR8 | G patch domain-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 114 | 808 | 92 | 92 | 0 |
| HADHA | HADHA | P40939 | Trifunctional enzyme subunit alpha, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 72 | 19 | 2 | 2 | 5 |
| HAP1_ENST00000310778 | HAP1 | P54257 | Huntingtin-associated protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 97 | 454 | 60 | 60 | 0 |
| HK1_ENST00000359426 | HK1 | P19367 | Hexokinase-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 127 | 75 | 16 | 16 | 6 |
| HK2 | HK2 | P52789 | Hexokinase-2 | chr2 | Not Cancer Driver | No | 1 | hippie | 138 | 77 | 7 | 7 | 0 |
| HNRNPH1 | HNRNPH1 | P31943 | Heterogeneous nuclear ribonucleoprotein H | chr5 | Not Cancer Driver | No | 1 | hippie | 51 | 169 | 29 | 29 | 0 |
| HSD17B10 | HSD17B10 | Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | chrX | Not Cancer Driver | No | 1 | hippie | 27 | 15 | 3 | 3 | 11 |
| IARS2 | IARS2 | Q9NSE4 | Isoleucine--tRNA ligase, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 149 | 145 | 22 | 22 | 0 |
| IMMP2L_ENST00000452895 | IMMP2L | Q96T52 | Mitochondrial inner membrane protease subunit 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 36 | 29 | 7 | 7 | 0 |
| IMMT | IMMT | Q16891 | MICOS complex subunit MIC60 | chr2 | Not Cancer Driver | No | 1 | hippie | 97 | 400 | 50 | 50 | 0 |
| INF2 | INF2 | Q27J81 | Inverted formin-2 | chr14 | Not Cancer Driver | No | 1 | hippie | 120 | 635 | 49 | 49 | 30 |
| JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
| KIAA1671_ENST00000406486 | KIAA1671 | Q9BY89 | Uncharacterized protein KIAA1671 | chr22 | Not Cancer Driver | No | 1 | hippie | 14 | 1759 | 14 | 14 | 0 |
| LARP4_ENST00000398473 | LARP4 | Q71RC2 | La-related protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie | 86 | 486 | 53 | 53 | 0 |
| LIMA1_ENST00000341247 | LIMA1 | Q9UHB6 | LIM domain and actin-binding protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 88 | 687 | 81 | 81 | 0 |
| LSG1 | LSG1 | Q9H089 | Large subunit GTPase 1 homolog | chr3 | Not Cancer Driver | No | 1 | hippie | 73 | 369 | 42 | 42 | 0 |
| MAP1LC3B | MAP1LC3B | Q9GZQ8 | Microtubule-associated proteins 1A/1B light chain 3B | chr16 | Not Cancer Driver | No | 1 | hippie | 10 | 17 | 1 | 1 | 0 |
| MAP3K7 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | Not Cancer Driver | No | 1 | hippie | 104 | 333 | 66 | 66 | 6 |
| MAPK6 | MAPK6 | Q16659 | Mitogen-activated protein kinase 6 | chr15 | Not Cancer Driver | No | 1 | hippie | 79 | 165 | 20 | 20 | 0 |
| MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | Not Cancer Driver | No | 1 | hippie | 128 | 750 | 126 | 126 | 18 |
| MAVS | MAVS | Q7Z434 | Mitochondrial antiviral-signaling protein | chr20 | Not Cancer Driver | No | 1 | hippie | 70 | 411 | 58 | 58 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | hippie | 56 | 297 | 37 | 37 | 0 |
| MFF | MFF | Q9GZY8 | Mitochondrial fission factor | chr2 | Not Cancer Driver | No | 1 | hippie | 59 | 264 | 47 | 47 | 0 |
| MIA3 | MIA3 | Q5JRA6 | Transport and Golgi organization protein 1 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 1490 | 178 | 178 | 0 |
| MIEF1_ENST00000404569 | MIEF1 | Q9NQG6 | Mitochondrial dynamics protein MID51 | chr22 | Not Cancer Driver | No | 1 | hippie | 65 | 94 | 9 | 9 | 0 |
| MIEF2_ENST00000323019 | MIEF2 | Q96C03 | Mitochondrial dynamics protein MID49 | chr17 | Not Cancer Driver | No | 1 | hippie | 43 | 89 | 9 | 9 | 0 |
| MIGA1_ENST00000370791 | MIGA1 | Q8NAN2 | Mitoguardin 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 83 | 34 | 6 | 6 | 0 |
| MOV10_ENST00000357443 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 101 | 8 | 8 | 0 |
| MTFR1 | MTFR1 | Q15390 | Mitochondrial fission regulator 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 41 | 230 | 27 | 27 | 0 |
| MTFR2 | MTFR2 | Q6P444 | Mitochondrial fission regulator 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 32 | 240 | 20 | 20 | 0 |
| MTHFD1L_ENST00000367321 | MTHFD1L | Q6UB35 | Monofunctional C1-tetrahydrofolate synthase, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie | 117 | 139 | 11 | 11 | 0 |
| NCSTN | NCSTN | Q92542 | Nicastrin | chr1 | Not Cancer Driver | No | 1 | hippie | 94 | 72 | 11 | 11 | 1 |
| NDUFB4 | NDUFB4 | O95168 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 20 | 1 | 1 | 0 |
| NDUFS4 | NDUFS4 | O43181 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 92 | 17 | 17 | 1 |
| NEDD1_ENST00000266742 | NEDD1 | Q8NHV4 | Protein NEDD1 | chr12 | Not Cancer Driver | No | 1 | hippie | 87 | 282 | 36 | 36 | 0 |
| NFXL1 | NFXL1 | Q6ZNB6 | NF-X1-type zinc finger protein NFXL1 | chr4 | Not Cancer Driver | No | 1 | hippie | 102 | 183 | 15 | 15 | 0 |
| NME3 | NME3 | Q13232 | Nucleoside diphosphate kinase 3 | chr16 | Not Cancer Driver | No | 1 | hippie | 10 | 4 | 0 | 0 | 0 |
| NSF | NSF | P46459 | Vesicle-fusing ATPase | chr17 | Not Cancer Driver | No | 1 | hippie | 47 | 84 | 3 | 3 | 2 |
| NUDT19 | NUDT19 | A8MXV4 | Acyl-coenzyme A diphosphatase NUDT19 | chr19 | Not Cancer Driver | No | 1 | hippie | 27 | 131 | 5 | 5 | 0 |
| NUP107 | NUP107 | P57740 | Nuclear pore complex protein Nup107 | chr12 | Not Cancer Driver | No | 1 | hippie | 127 | 183 | 26 | 26 | 5 |
| NUP133 | NUP133 | Q8WUM0 | Nuclear pore complex protein Nup133 | chr1 | Not Cancer Driver | No | 1 | hippie | 143 | 116 | 16 | 16 | 3 |
| NUP155 | NUP155 | O75694 | Nuclear pore complex protein Nup155 | chr5 | Not Cancer Driver | No | 1 | hippie | 154 | 221 | 19 | 19 | 1 |
| NUP160 | NUP160 | Q12769 | Nuclear pore complex protein Nup160 | chr11 | Not Cancer Driver | No | 1 | hippie | 138 | 48 | 1 | 1 | 0 |
| NUP205 | NUP205 | Q92621 | Nuclear pore complex protein Nup205 | chr7 | Not Cancer Driver | No | 1 | hippie | 251 | 101 | 16 | 16 | 1 |
| NUP93 | NUP93 | Q8N1F7 | Nuclear pore complex protein Nup93 | chr16 | Not Cancer Driver | No | 1 | hippie | 97 | 158 | 23 | 23 | 3 |
| NUP98_ENST00000359171 | NUP98 | P52948 | Nuclear pore complex protein Nup98-Nup96 | chr11 | Census | Yes | 1 | hippie | 227 | 1008 | 107 | 107 | 0 |
| NXF1_ENST00000294172 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 100 | 163 | 32 | 32 | 0 |
| OCIAD1 | OCIAD1 | Q9NX40 | OCIA domain-containing protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 169 | 25 | 25 | 0 |
| OPA3_ENST00000263275 | OPA3 | Q9H6K4 | Optic atrophy 3 protein | chr19 | Not Cancer Driver | No | 1 | hippie | 18 | 44 | 7 | 7 | 2 |
| OPTN_ENST00000263036 | OPTN | Q96CV9 | Optineurin | chr10 | Not Cancer Driver | No | 1 | hippie | 58 | 470 | 51 | 51 | 6 |
| OTC | OTC | P00480 | Ornithine transcarbamylase, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie | 89 | 24 | 4 | 4 | 111 |
| OTUD1 | OTUD1 | Q5VV17 | OTU domain-containing protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 9 | 279 | 2 | 2 | 0 |
| PABPC4_ENST00000372857 | PABPC4 | Q13310 | Polyadenylate-binding protein 4 | chr1 | Not Cancer Driver | No | 1 | hippie | 89 | 253 | 49 | 49 | 0 |
| PCK2 | PCK2 | Q16822 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie | 91 | 139 | 13 | 13 | 0 |
| PEAK1_ENST00000312493 | PEAK1 | Q9H792 | Inactive tyrosine-protein kinase PEAK1 | chr15 | Not Cancer Driver | No | 1 | hippie | 222 | 1232 | 150 | 150 | 0 |
| PEX14 | PEX14 | O75381 | Peroxisomal membrane protein PEX14 | chr1 | Not Cancer Driver | No | 1 | hippie | 38 | 266 | 28 | 28 | 0 |
| PEX19 | PEX19 | P40855 | Peroxisomal biogenesis factor 19 | chr1 | Not Cancer Driver | No | 1 | hippie | 41 | 266 | 38 | 38 | 0 |
| PEX5_ENST00000420616 | PEX5 | P50542 | Peroxisomal targeting signal 1 receptor | chr12 | Not Cancer Driver | No | 1 | hippie | 73 | 321 | 36 | 36 | 2 |
| PIK3C2A | PIK3C2A | O00443 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | chr11 | Not Cancer Driver | No | 1 | hippie | 187 | 350 | 43 | 43 | 0 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 57 | 99 | 13 | 13 | 23 |
| PLD6 | PLD6 | Q8N2A8 | Mitochondrial cardiolipin hydrolase | chr17 | Not Cancer Driver | No | 1 | hippie | 27 | 24 | 6 | 6 | 0 |
| PML | PML | P29590 | Protein PML | chr15 | Census, Compendium | Yes | 1 | hippie | 112 | 312 | 34 | 34 | 0 |
| POLG_ENST00000442287 | POLG | P54098 | DNA polymerase subunit gamma-1 | chr15 | Census | Yes | 1 | hippie | 139 | 421 | 42 | 42 | 73 |
| PPHLN1_ENST00000610488 | PPHLN1 | Q8NEY8 | Periphilin-1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 447 | 62 | 62 | 0 |
| PRC1 | PRC1 | O43663 | Protein regulator of cytokinesis 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 63 | 235 | 26 | 26 | 0 |
| PRKAR2A | PRKAR2A | P13861 | cAMP-dependent protein kinase type II-alpha regulatory subunit | chr3 | Not Cancer Driver | No | 1 | hippie | 37 | 149 | 13 | 13 | 0 |
| PRKAR2B | PRKAR2B | P31323 | cAMP-dependent protein kinase type II-beta regulatory subunit | chr7 | Not Cancer Driver | No | 1 | hippie | 60 | 125 | 4 | 4 | 0 |
| PRKCE | PRKCE | Q02156 | Protein kinase C epsilon type | chr2 | Not Cancer Driver | No | 1 | hippie | 107 | 170 | 26 | 26 | 0 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 78 | 15 | 15 | 31 |
| PROSER1 | PROSER1 | Q86XN7 | Proline and serine-rich protein 1 | chr13 | Not Cancer Driver | No | 1 | hippie | 126 | 645 | 86 | 86 | 0 |
| PTN | PTN | P21246 | Pleiotrophin | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 51 | 11 | 11 | 0 |
| PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 49 | 140 | 25 | 25 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 1 | biogrid | 27 | 11 | 0 | 0 | 4 |
| RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
| RHOT2 | RHOT2 | Q8IXI1 | Mitochondrial Rho GTPase 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 52 | 79 | 5 | 5 | 0 |
| RMDN2_ENST00000406384 | RMDN2 | Q96LZ7 | Regulator of microtubule dynamics protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 28 | 81 | 5 | 5 | 0 |
| RMDN3 | RMDN3 | Q96TC7 | Regulator of microtubule dynamics protein 3 | chr15 | Not Cancer Driver | No | 1 | hippie | 45 | 196 | 17 | 17 | 0 |
| RNF144B | RNF144B | Q7Z419 | E3 ubiquitin-protein ligase RNF144B | chr6 | Not Cancer Driver | No | 1 | hippie | 32 | 4 | 1 | 1 | 0 |
| SARM1 | SARM1 | Q6SZW1 | NAD(+) hydrolase SARM1 | chr17 | Not Cancer Driver | No | 1 | hippie | 36 | 80 | 4 | 4 | 0 |
| SASS6 | SASS6 | Q6UVJ0 | Spindle assembly abnormal protein 6 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 82 | 331 | 37 | 37 | 1 |
| SCO1 | SCO1 | O75880 | Protein SCO1 homolog, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie | 35 | 79 | 7 | 7 | 1 |
| SCYL2_ENST00000360820 | SCYL2 | Q6P3W7 | SCY1-like protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 103 | 328 | 29 | 29 | 0 |
| SEC63 | SEC63 | Q9UGP8 | Translocation protein SEC63 homolog | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 98 | 266 | 37 | 37 | 0 |
| SEL1L2_ENST00000284951 | SEL1L2 | Q5TEA6 | Protein sel-1 homolog 2 | chr20 | Not Cancer Driver | No | 1 | hippie | 177 | 71 | 18 | 18 | 0 |
| SFXN1 | SFXN1 | Q9H9B4 | Sideroflexin-1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 29 | 1 | 1 | 0 |
| SFXN3_ENST00000393459 | SFXN3 | Q9BWM7 | Sideroflexin-3 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 0 | 0 | 0 | 0 |
| SLC25A3 | SLC25A3 | Q00325 | Phosphate carrier protein, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 32 | 4 | 4 | 1 |
| SLC25A5 | SLC25A5 | P05141 | ADP/ATP translocase 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 0 | 0 | 0 | 0 |
| SLC25A6 | SLC25A6 | P12236 | ADP/ATP translocase 3 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 0 | 0 | 0 | 0 |
| SMCR8 | SMCR8 | Q8TEV9 | Guanine nucleotide exchange protein SMCR8 | chr17 | Not Cancer Driver | No | 1 | hippie | 107 | 357 | 38 | 38 | 0 |
| SMG7_ENST00000347615 | SMG7 | Q92540 | Nonsense-mediated mRNA decay factor SMG7 | chr1 | Not Cancer Driver | No | 1 | hippie | 134 | 664 | 82 | 82 | 0 |
| SNAP29 | SNAP29 | O95721 | Synaptosomal-associated protein 29 | chr22 | Not Cancer Driver | No | 1 | hippie | 21 | 246 | 20 | 20 | 0 |
| SNAP47_ENST00000366759 | SNAP47 | Q5SQN1 | Synaptosomal-associated protein 47 | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 192 | 20 | 20 | 0 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | Not Cancer Driver | No | 1 | hippie | 21 | 107 | 13 | 13 | 5 |
| SRSF1 | SRSF1 | Q07955 | Serine/arginine-rich splicing factor 1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 198 | 34 | 34 | 0 |
| SUFU | SUFU | Q9UMX1 | Suppressor of fused homolog | chr10 | Census | Yes | 1 | hippie | 55 | 199 | 19 | 19 | 2 |
| SUPT16H | SUPT16H | Q9Y5B9 | FACT complex subunit SPT16 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 147 | 301 | 44 | 44 | 0 |
| SYAP1 | SYAP1 | Q96A49 | Synapse-associated protein 1 | chrX | Not Cancer Driver | No | 1 | hippie | 31 | 221 | 22 | 22 | 0 |
| SYNPO2L | SYNPO2L | Q9H987 | Synaptopodin 2-like protein | chr10 | Not Cancer Driver | No | 1 | hippie | 103 | 950 | 99 | 99 | 0 |
| TAB1 | TAB1 | Q15750 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 81 | 232 | 34 | 34 | 0 |
| TACC1 | TACC1 | O75410 | Transforming acidic coiled-coil-containing protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 82 | 654 | 69 | 69 | 0 |
| TACC2_ENST00000334433 | TACC2 | O95359 | Transforming acidic coiled-coil-containing protein 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 475 | 2730 | 444 | 444 | 0 |
| TDRKH_ENST00000368827 | TDRKH | Q9Y2W6 | Tudor and KH domain-containing protein | chr1 | Not Cancer Driver | No | 1 | hippie | 76 | 185 | 27 | 27 | 0 |
| TEX2_ENST00000583097 | TEX2 | Q8IWB9 | Testis-expressed protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 136 | 636 | 71 | 71 | 0 |
| TIMM17B_ENST00000376582 | TIMM17B | O60830 | Mitochondrial import inner membrane translocase subunit Tim17-B | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 27 | 4 | 4 | 0 |
| TMEM131 | TMEM131 | Q92545 | Transmembrane protein 131 | chr2 | Not Cancer Driver | No | 1 | hippie | 258 | 765 | 118 | 118 | 0 |
| TMEM192 | TMEM192 | Q8IY95 | Transmembrane protein 192 | chr4 | Not Cancer Driver | No | 1 | hippie | 31 | 5 | 1 | 1 | 0 |
| TNRC6A | TNRC6A | Q8NDV7 | Trinucleotide repeat-containing gene 6A protein | chr16 | Not Cancer Driver | No | 1 | hippie | 284 | 1830 | 265 | 265 | 0 |
| TNRC6B | TNRC6B | Q9UPQ9 | Trinucleotide repeat-containing gene 6B protein | chr22 | Not Cancer Driver | No | 1 | hippie | 205 | 1735 | 195 | 195 | 0 |
| TNRC6C_ENST00000301624 | TNRC6C | Q9HCJ0 | Trinucleotide repeat-containing gene 6C protein | chr17 | Not Cancer Driver | No | 1 | hippie | 170 | 1564 | 162 | 162 | 0 |
| TOMM20 | TOMM20 | Q15388 | Mitochondrial import receptor subunit TOM20 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 8 | 25 | 1 | 1 | 0 |
| TOMM22 | TOMM22 | Q9NS69 | Mitochondrial import receptor subunit TOM22 homolog | chr22 | Not Cancer Driver | No | 3 | hippie, biogrid | 18 | 83 | 9 | 9 | 0 |
| TOMM40_ENST00000405636 | TOMM40 | O96008 | Mitochondrial import receptor subunit TOM40 homolog | chr19 | Not Cancer Driver | No | 3 | hippie, biogrid | 17 | 98 | 1 | 1 | 0 |
| TOMM7 | TOMM7 | Q9P0U1 | Mitochondrial import receptor subunit TOM7 homolog | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 0 | 0 | 0 | 0 |
| TOMM70 | TOMM70 | O94826 | Mitochondrial import receptor subunit TOM70 | chr3 | Not Cancer Driver | No | 1 | hippie | 59 | 140 | 8 | 8 | 0 |
| TPP1 | TPP1 | O14773 | Tripeptidyl-peptidase 1 | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 67 | 92 | 7 | 7 | 37 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | Not Cancer Driver | No | 1 | hippie | 67 | 62 | 7 | 7 | 0 |
| TRAK1 | TRAK1 | Q9UPV9 | Trafficking kinesin-binding protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 118 | 619 | 74 | 74 | 0 |
| TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
| TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
| TTC1 | TTC1 | Q99614 | Tetratricopeptide repeat protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 28 | 211 | 21 | 21 | 0 |
| TTK | TTK | P33981 | Dual specificity protein kinase TTK | chr6 | Not Cancer Driver | No | 1 | hippie | 136 | 352 | 46 | 46 | 0 |
| UBXN4 | UBXN4 | Q92575 | UBX domain-containing protein 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 69 | 302 | 41 | 41 | 0 |
| UCP1 | UCP1 | P25874 | Mitochondrial brown fat uncoupling protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 43 | 1 | 0 | 0 | 0 |
| UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 141 | 24 | 24 | 0 |
| USP30 | USP30 | Q70CQ3 | Ubiquitin carboxyl-terminal hydrolase 30 | chr12 | Not Cancer Driver | No | 1 | hippie | 76 | 136 | 26 | 26 | 0 |
| UTP18 | UTP18 | Q9Y5J1 | U3 small nucleolar RNA-associated protein 18 homolog | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 250 | 21 | 21 | 0 |
| VAPB | VAPB | O95292 | Vesicle-associated membrane protein-associated protein B/C | chr20 | Not Cancer Driver | No | 1 | hippie | 16 | 138 | 8 | 8 | 3 |
| VDAC1_ENST00000395047 | VDAC1 | P21796 | Voltage-dependent anion-selective channel protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 38 | 36 | 4 | 4 | 0 |
| VDAC2_ENST00000543351 | VDAC2 | P45880 | Voltage-dependent anion-selective channel protein 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 35 | 9 | 1 | 1 | 0 |
| VPS13A | VPS13A | Q96RL7 | Intermembrane lipid transfer protein VPS13A | chr9 | Not Cancer Driver | No | 1 | hippie | 375 | 208 | 18 | 18 | 6 |
| VPS13D | VPS13D | Q5THJ4 | Intermembrane lipid transfer protein VPS13D | chr1 | Not Cancer Driver | No | 1 | hippie | 501 | 973 | 118 | 118 | 8 |
| WDR41 | WDR41 | Q9HAD4 | WD repeat-containing protein 41 | chr5 | Not Cancer Driver | No | 1 | hippie | 48 | 23 | 2 | 2 | 0 |
| YKT6 | YKT6 | O15498 | Synaptobrevin homolog YKT6 | chr7 | Not Cancer Driver | No | 1 | hippie | 19 | 21 | 2 | 2 | 0 |
| ZC3H18_ENST00000301011 | ZC3H18 | Q86VM9 | Zinc finger CCCH domain-containing protein 18 | chr16 | Not Cancer Driver | No | 1 | hippie | 139 | 929 | 134 | 134 | 0 |
| ZC3HAV1 | ZC3HAV1 | Q7Z2W4 | Zinc finger CCCH-type antiviral protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 142 | 344 | 63 | 63 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|