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TOE1 ,TOE1 ,Q96GM8
  • Number of Interaction partner in intact: 31
  • Number of Interaction partner in biogrid: 52
  • Number of Interaction partner in hippie: 116
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCF3 ABCF3 Q9NUQ8 ATP-binding cassette sub-family F member 3 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 109 136 19 19 0
AGGF1 AGGF1 Q8N302 Angiogenic factor with G patch and FHA domains 1 chr5 Not Cancer Driver No 1 hippie 100 582 80 80 1
AP2A1 AP2A1 O95782 AP-2 complex subunit alpha-1 chr19 Not Cancer Driver No 1 intact, hippie 95 188 12 12 0
APLP1 APLP1 P51693 Amyloid beta precursor like protein 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 146 455 98 98 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 intact, hippie 128 418 71 71 17
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
CA12 CA12 O43570 Carbonic anhydrase 12 chr15 Not Cancer Driver No 1 hippie 41 40 7 7 2
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 161 88 7 7 0
CCDC22 CCDC22 O60826 Coiled-coil domain-containing protein 22 chrX Not Cancer Driver No 1 intact, hippie 62 243 18 18 2
CD2BP2 CD2BP2 O95400 CD2 antigen cytoplasmic tail-binding protein 2 chr16 Not Cancer Driver No 1 hippie, biogrid 49 259 40 40 0
CIAO1 CIAO1 O76071 Probable cytosolic iron-sulfur protein assembly protein CIAO1 chr2 Not Cancer Driver No 1 hippie 30 20 2 2 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CLCN2 CLCN2 P51788 Chloride channel protein 2 chr3 Not Cancer Driver No 1 intact, hippie 124 224 38 38 8
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 intact, hippie 50 174 27 27 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 Not Cancer Driver No 1 hippie, biogrid 35 59 6 6 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 hippie 94 646 93 93 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
FGF17 FGF17 O60258 Fibroblast growth factor 17 chr8 Not Cancer Driver No 1 hippie, biogrid 30 107 16 16 3
FUS FUS P35637 RNA-binding protein FUS chr16 Census Yes 1 hippie 51 524 51 51 20
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 Not Cancer Driver No 1 hippie 9 11 0 0 0
HIST1H1A H1-1 Q02539 Histone H1.1 chr6 Not Cancer Driver No 1 intact 37 210 35 35 0
HIST1H1E H1-4 P10412 Histone H1.4 chr6 Not Cancer Driver No 1 intact 66 213 63 63 0
HIST1H1T H1-6 P22492 Histone H1t chr6 Not Cancer Driver No 1 intact 49 158 38 38 0
HNRNPF_ENST00000356053 HNRNPF P52597 Heterogeneous nuclear ribonucleoprotein F chr10 Not Cancer Driver No 1 intact, hippie 65 105 18 18 0
IFIT1 IFIT1 P09914 Interferon-induced protein with tetratricopeptide repeats 1 chr10 Not Cancer Driver No 1 hippie 49 52 3 3 0
IFIT2_ENST00000371826 IFIT2 P09913 Interferon-induced protein with tetratricopeptide repeats 2 chr10 Not Cancer Driver No 1 intact, hippie 73 85 17 17 0
IK IK Q13123 Protein Red chr5 Not Cancer Driver No 1 hippie 61 482 50 50 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 Census, Compendium Yes 1 hippie 177 88 48 48 1
KRR1 KRR1 Q13601 KRR1 small subunit processome component homolog chr12 Not Cancer Driver No 1 hippie, biogrid 37 194 23 23 0
KSR2_ENST00000339824 KSR2 Q6VAB6 Kinase suppressor of Ras 2 chr12 Not Cancer Driver No 1 intact, hippie 231 434 120 120 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie, biogrid 58 350 44 44 0
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 Not Cancer Driver No 1 hippie, biogrid 37 86 12 12 0
LLPH_ENST00000446587 LLPH Q9BRT6 Protein LLP homolog chr12 Not Cancer Driver No 1 hippie, biogrid 15 113 14 14 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LSM4 LSM4 Q9Y4Z0 U6 snRNA-associated Sm-like protein LSm4 chr19 Not Cancer Driver No 1 hippie 19 64 9 9 0
MAGEB2 MAGEB2 O15479 Melanoma-associated antigen B2 chrX Not Cancer Driver No 1 hippie, biogrid 98 126 35 35 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NEIL1_ENST00000564784 NEIL1 Q96FI4 Endonuclease 8-like 1 chr15 Not Cancer Driver No 1 hippie, biogrid 41 165 14 14 0
NIFK NIFK Q9BYG3 MKI67 FHA domain-interacting nucleolar phosphoprotein chr2 Not Cancer Driver No 1 hippie, biogrid 32 148 15 15 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
PIM2 PIM2 Q9P1W9 Serine/threonine-protein kinase pim-2 chrX Not Cancer Driver No 1 hippie 43 47 10 10 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PNN PNN Q9H307 Pinin chr14 Not Cancer Driver No 1 hippie 94 700 90 90 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 intact, hippie 38 27 6 6 0
PRCC PRCC Q92733 Proline-rich protein PRCC chr1 Census Yes 1 intact, hippie 58 469 57 57 0
PRPF4 PRPF4 O43172 U4/U6 small nuclear ribonucleoprotein Prp4 chr9 Not Cancer Driver No 1 hippie 61 152 15 15 2
PRR3 PRR3 P79522 Proline-rich protein 3 chr6 Not Cancer Driver No 1 hippie, biogrid 11 165 10 10 0
PYM1 PYM1 Q9BRP8 Partner of Y14 and mago chr12 Not Cancer Driver No 1 hippie 22 204 22 22 0
RAB40C_ENST00000539661 RAB40C Q96S21 Ras-related protein Rab-40C chr16 Not Cancer Driver No 1 hippie 46 38 10 10 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 59 328 43 43 0
RASA2 RASA2 Q15283 Ras GTPase-activating protein 2 chr3 Compendium Yes 1 hippie, biogrid 104 142 19 19 0
RBM19 RBM19 Q9Y4C8 Probable RNA-binding protein 19 chr12 Not Cancer Driver No 1 hippie, biogrid 146 514 76 76 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RBM8A_ENST00000632555 RBM8A Q9Y5S9 RNA-binding protein 8A chr1 Not Cancer Driver No 1 hippie 35 135 32 32 0
RBMS2 RBMS2 Q15434 RNA-binding motif, single-stranded-interacting protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 53 265 38 38 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 Not Cancer Driver No 1 hippie 69 301 37 37 0
RPL19 RPL19 P84098 60S ribosomal protein L19 chr17 Not Cancer Driver No 1 hippie, biogrid 30 121 21 21 0
RPL23A RPL23A P62750 60S ribosomal protein L23a chr17 Not Cancer Driver No 1 hippie, biogrid 21 70 13 13 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 Not Cancer Driver No 1 hippie, biogrid 16 114 13 13 0
RPL3 RPL3 P39023 60S ribosomal protein L3 chr22 Not Cancer Driver No 1 hippie, biogrid 34 79 3 3 0
RPL31_ENST00000264258 RPL31 P62899 60S ribosomal protein L31 chr2 Not Cancer Driver No 1 hippie, biogrid 19 69 14 14 0
RPL7A RPL7A P62424 60S ribosomal protein L7a chr9 Not Cancer Driver No 1 hippie, biogrid 27 100 5 5 0
RPS10_ENST00000467531 RPS10 P46783 40S ribosomal protein S10 chr6 Not Cancer Driver No 1 hippie, biogrid 25 100 19 19 0
RPS16 RPS16 P62249 40S ribosomal protein S16 chr19 Not Cancer Driver No 1 hippie, biogrid 16 14 1 1 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 Not Cancer Driver No 1 hippie, biogrid 15 61 3 3 23
RPS2 RPS2 P15880 40S ribosomal protein S2 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 34 85 14 14 0
RPS3A RPS3A P61247 40S ribosomal protein S3a chr4 Compendium Yes 1 intact, hippie, biogrid 21 85 5 5 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 Not Cancer Driver No 1 hippie, biogrid 22 48 4 4 0
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 Not Cancer Driver No 1 hippie, biogrid 23 34 5 5 0
SART3 SART3 Q15020 Squamous cell carcinoma antigen recognized by T-cells 3 chr12 Not Cancer Driver No 2 hippie, biogrid 101 404 45 45 0
SERBP1 SERBP1 Q8NC51 Plasminogen activator inhibitor 1 RNA-binding protein chr1 Not Cancer Driver No 1 hippie 53 408 53 53 0
SF1_ENST00000377390 SF1 Q15637 Splicing factor 1 chr11 Not Cancer Driver No 1 hippie 110 627 106 106 0
SF3B2 SF3B2 Q13435 Splicing factor 3B subunit 2 chr11 Not Cancer Driver No 1 intact, hippie 110 804 105 105 0
SF3B3 SF3B3 Q15393 Splicing factor 3B subunit 3 chr16 Not Cancer Driver No 1 intact, hippie 154 145 19 19 0
SH3GL3_ENST00000427482 SH3GL3 Q99963 Endophilin-A3 chr15 Not Cancer Driver No 1 hippie, biogrid 88 83 23 23 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 Not Cancer Driver No 1 hippie 41 82 10 10 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 177 34 8 8 0
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 2 intact, hippie, biogrid 38 416 37 37 0
SNRPA1 SNRPA1 P09661 U2 small nuclear ribonucleoprotein A' chr15 Not Cancer Driver No 3 intact, hippie, biogrid 33 93 14 14 0
SNRPB SNRPB P14678 Small nuclear ribonucleoprotein-associated proteins B and B' chr20 Not Cancer Driver No 1 hippie, biogrid 39 182 34 34 4
SNRPB2_ENST00000377943 SNRPB2 P08579 U2 small nuclear ribonucleoprotein B'' chr20 Not Cancer Driver No 1 hippie, biogrid 18 100 7 7 0
SNRPC SNRPC P09234 U1 small nuclear ribonucleoprotein C chr6 Not Cancer Driver No 1 hippie, biogrid 26 143 26 26 0
SNRPD3 SNRPD3 P62318 Small nuclear ribonucleoprotein Sm D3 chr22 Not Cancer Driver No 1 hippie, biogrid 20 43 13 13 0
SNRPE SNRPE P62304 Small nuclear ribonucleoprotein E chr1 Not Cancer Driver No 2 intact, hippie, biogrid 16 0 0 0 1
SNRPF SNRPF P62306 Small nuclear ribonucleoprotein F chr12 Not Cancer Driver No 2 intact, hippie, biogrid 4 10 0 0 0
SNRPG_ENST00000272348 SNRPG P62308 Small nuclear ribonucleoprotein G chr2 Not Cancer Driver No 2 hippie, biogrid 8 9 3 3 0
SNRPN_ENST00000577565 SNRPN P63162 Small nuclear ribonucleoprotein-associated protein N chr15 Not Cancer Driver No 2 hippie, biogrid 92 184 79 79 0
SNUPN_ENST00000564675 SNUPN O95149 Snurportin-1 chr15 Not Cancer Driver No 3 hippie, biogrid 45 137 17 17 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 intact, hippie 54 267 32 32 30
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 Not Cancer Driver No 1 hippie, biogrid 78 343 46 46 0
SRSF4 SRSF4 Q08170 Serine/arginine-rich splicing factor 4 chr1 Not Cancer Driver No 1 hippie, biogrid 67 409 55 55 0
SRSF6 SRSF6 Q13247 Serine/arginine-rich splicing factor 6 chr20 Not Cancer Driver No 1 hippie 69 259 49 49 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 10 76 7 7 0
SURF6 SURF6 O75683 Surfeit locus protein 6 chr9 Not Cancer Driver No 1 hippie, biogrid 58 337 56 56 0
TOE1 TOE1 Q96GM8 Target of EGR1 protein 1 chr1 Not Cancer Driver No 1 hippie 44 210 22 22 10
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 intact, hippie 2891 282 1466 1466 83
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
U2AF1 U2AF1 Q01081 Splicing factor U2AF 35 kDa subunit chr21 Census, Compendium Yes 1 hippie 70 73 13 13 3
UNC13B_ENST00000378495 UNC13B O14795 Protein unc-13 homolog B chr9 Not Cancer Driver No 1 hippie 214 448 77 77 0
UTP23 UTP23 Q9BRU9 rRNA-processing protein UTP23 homolog chr8 Not Cancer Driver No 1 hippie, biogrid 35 97 16 16 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 Not Cancer Driver No 1 intact, hippie 30 41 2 2 0
WDR83 WDR83 Q9BRX9 WD repeat domain-containing protein 83 chr19 Not Cancer Driver No 1 intact, hippie 28 35 3 3 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 79 108 9 9 3
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
YBX2 YBX2 Q9Y2T7 Y-box-binding protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 48 342 46 46 0
ZBTB47 ZBTB47 Q9UFB7 Zinc finger and BTB domain-containing protein 47 chr3 Not Cancer Driver No 1 hippie, biogrid 52 402 18 18 0
ZNF346_ENST00000358149 ZNF346 Q9UL40 Zinc finger protein 346 chr5 Not Cancer Driver No 1 hippie, biogrid 29 175 17 17 0
ZNF467 ZNF467 Q7Z7K2 Zinc finger protein 467 chr7 Not Cancer Driver No 1 hippie, biogrid 75 345 37 37 0
ZNF668_ENST00000535577 ZNF668 Q96K58 Zinc finger protein 668 chr16 Not Cancer Driver No 1 hippie, biogrid 100 314 54 54 0