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TNFRSF14 ,TNFRSF14 ,Q92956
  • Uniprot Accession= Q92956
  • Ensembl Transcript= ENST00000355716.4
  • Uniprot Name= TNFRSF14
  • Name= Tumor necrosis factor receptor superfamily member 14
  • Chromosome= chr1
  • Driver status= Census, Compendium
  • Number of Interaction partner in intact: 48
  • Number of Interaction partner in biogrid: 6
  • Number of Interaction partner in hippie: 80
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
A2M A2M P01023 Alpha-2-macroglobulin chr12 Not Cancer Driver No 1 hippie 260 144 22 22 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 intact, hippie 88 166 22 22 11
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ATXN10 ATXN10 Q9UBB4 Ataxin-10 chr22 Not Cancer Driver No 1 hippie 46 37 2 2 0
BTLA BTLA Q7Z6A9 B- and T-lymphocyte attenuator chr3 Not Cancer Driver No 2 intact, hippie 31 57 5 5 0
C19orf70_ENST00000309324 MICOS13 Q5XKP0 MICOS complex subunit MIC13 chr19 Not Cancer Driver No 1 intact, hippie 12 3 0 0 0
CCDC59 CCDC59 Q9P031 Thyroid transcription factor 1-associated protein 26 chr12 Not Cancer Driver No 1 hippie 34 206 27 27 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 Not Cancer Driver No 1 intact, hippie 20 2 0 0 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 intact, hippie 52 214 31 31 0
CEP126 CEP126 Q9P2H0 Centrosomal protein of 126 kDa chr11 Not Cancer Driver No 1 intact, hippie 197 840 151 151 0
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie, biogrid 235 1015 122 122 18
CNIH4 CNIH4 Q9P003 Protein cornichon homolog 4 chr1 Not Cancer Driver No 1 intact, hippie 13 0 0 0 0
DCD_ENST00000293371 DCD P81605 Dermcidin chr12 Not Cancer Driver No 1 hippie 25 67 19 19 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DGKD DGKD Q16760 Diacylglycerol kinase delta chr2 Not Cancer Driver No 1 hippie 160 441 60 60 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 Compendium Yes 1 intact, hippie 182 331 42 42 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 intact, hippie 37 153 16 16 0
DPM1_ENST00000371588 DPM1 O60762 Dolichol-phosphate mannosyltransferase subunit 1 chr20 Not Cancer Driver No 1 intact, hippie 38 29 6 6 3
DRAP1 DRAP1 Q14919 Dr1-associated corepressor chr11 Not Cancer Driver No 1 hippie 28 170 22 22 0
DYNLL1_ENST00000242577 DYNLL1 P63167 Dynein light chain 1, cytoplasmic chr12 Not Cancer Driver No 1 intact, hippie 9 0 0 0 0
EIF3E EIF3E P60228 Eukaryotic translation initiation factor 3 subunit E chr8 Census, Compendium Yes 1 intact, hippie 73 27 1 1 0
EIF3I EIF3I Q13347 Eukaryotic translation initiation factor 3 subunit I chr1 Not Cancer Driver No 1 intact, hippie 47 46 6 6 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 Not Cancer Driver No 1 hippie 32 31 3 3 0
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 Not Cancer Driver No 1 hippie 327 117 16 16 0
GDI2 GDI2 P50395 Rab GDP dissociation inhibitor beta chr10 Not Cancer Driver No 1 hippie 49 23 2 2 0
GET4 GET4 Q7L5D6 Golgi to ER traffic protein 4 homolog chr7 Not Cancer Driver No 1 hippie 34 51 3 3 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 1 hippie 65 61 8 8 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX Not Cancer Driver No 1 intact, hippie 22 3 0 0 62
HSPBP1 HSPBP1 Q9NZL4 Hsp70-binding protein 1 chr19 Not Cancer Driver No 1 intact, hippie 29 130 7 7 0
HSPE1 HSPE1 P61604 10 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 8 3 0 0 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 Compendium Yes 1 hippie 44 127 9 9 2
IMPA2 IMPA2 O14732 Inositol monophosphatase 2 chr18 Not Cancer Driver No 1 hippie 44 21 1 1 0
ITFG1 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 intact, hippie 70 18 3 3 0
LHPP LHPP Q9H008 Phospholysine phosphohistidine inorganic pyrophosphate phosphatase chr10 Not Cancer Driver No 1 intact 32 20 1 1 0
LTA LTA P01374 Lymphotoxin-alpha chr6 Not Cancer Driver No 1 hippie 37 20 5 5 0
MAIP1 MAIP1 Q8WWC4 m-AAA protease-interacting protein 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 28 12 0 0 0
MBTPS1 MBTPS1 Q14703 Membrane-bound transcription factor site-1 protease chr16 Not Cancer Driver No 1 intact, hippie 140 206 36 36 1
MIF MIF P14174 Macrophage migration inhibitory factor chr22 Not Cancer Driver No 1 intact, hippie 4 0 0 0 0
MRM3 MRM3 Q9HC36 rRNA methyltransferase 3, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 45 83 8 8 0
NCLN NCLN Q969V3 Nicalin chr19 Not Cancer Driver No 1 intact, hippie 42 38 4 4 0
NDUFS2 NDUFS2 O75306 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 58 49 5 5 4
NRIP1_ENST00000400199 NRIP1 P48552 Nuclear receptor-interacting protein 1 chr21 Not Cancer Driver No 1 hippie 141 998 124 124 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 intact, hippie, biogrid 61 79 15 15 1
PCED1A PCED1A Q9H1Q7 PC-esterase domain-containing protein 1A chr20 Not Cancer Driver No 1 intact, hippie 55 167 22 22 0
PDIA6_ENST00000272227 PDIA6 Q15084 Protein disulfide-isomerase A6 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 55 82 11 11 0
PER2 PER2 O15055 Period circadian protein homolog 2 chr2 Not Cancer Driver No 1 hippie 166 782 101 101 1
PFDN2 PFDN2 Q9UHV9 Prefoldin subunit 2 chr1 Not Cancer Driver No 1 hippie 18 111 11 11 0
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 Not Cancer Driver No 1 intact, hippie 50 18 1 1 0
PSMA3 PSMA3 P25788 Proteasome subunit alpha type-3 chr14 Not Cancer Driver No 1 intact, hippie 27 30 5 5 0
PSMB1 PSMB1 P20618 Proteasome subunit beta type-1 chr6 Not Cancer Driver No 1 intact, hippie 25 14 2 2 0
PSPH_ENST00000275605 PSPH P78330 Phosphoserine phosphatase chr7 Not Cancer Driver No 1 intact, hippie 44 21 6 6 3
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 1 hippie 115 421 74 74 3
RPL36_ENST00000347512 RPL36 Q9Y3U8 60S ribosomal protein L36 chr19 Not Cancer Driver No 1 intact, hippie 7 66 4 4 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 1 intact, hippie 62 100 13 13 0
SEC11A_ENST00000268220 SEC11A P67812 Signal peptidase complex catalytic subunit SEC11A chr15 Not Cancer Driver No 1 intact, hippie, biogrid 20 0 0 0 0
SERPINA4_ENST00000298841 SERPINA4 P29622 Kallistatin chr14 Not Cancer Driver No 1 intact, hippie 114 19 4 4 0
SLC25A10_ENST00000350690 SLC25A10 Q9UBX3 Mitochondrial dicarboxylate carrier chr17 Not Cancer Driver No 1 hippie 33 0 0 0 0
SLC25A22_ENST00000628067 SLC25A22 Q9H936 Mitochondrial glutamate carrier 1 chr11 Not Cancer Driver No 1 hippie 34 22 2 2 1
SPCS2 SPCS2 Q15005 Signal peptidase complex subunit 2 chr11 Not Cancer Driver No 1 hippie 17 0 0 0 0
SRPRB SRPRB Q9Y5M8 Signal recognition particle receptor subunit beta chr3 Not Cancer Driver No 1 intact, hippie 30 23 3 3 0
SSB SSB P05455 Lupus La protein chr2 Not Cancer Driver No 1 intact, hippie 39 181 18 18 0
SSR4_ENST00000370086 SSR4 P51571 Translocon-associated protein subunit delta chrX Not Cancer Driver No 1 hippie 21 0 0 0 0
ST13 ST13 P50502 Hsc70-interacting protein chr22 Not Cancer Driver No 1 intact, hippie 38 297 29 29 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 2 intact, hippie 51 202 15 15 27
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 Census, Compendium Yes 1 hippie 33 54 8 8 0
TNFSF13 TNFSF13 O75888 Tumor necrosis factor ligand superfamily member 13 chr17 Not Cancer Driver No 1 hippie 14 109 6 6 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 Not Cancer Driver No 1 hippie 58 18 1 1 0
TRAF1 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 Not Cancer Driver No 1 intact, hippie 51 63 9 9 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 4 intact, hippie 63 4 1 1 0
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 Compendium Yes 1 intact, hippie 61 101 9 9 1
TRAF5_ENST00000336184 TRAF5 O00463 TNF receptor-associated factor 5 chr1 Not Cancer Driver No 1 hippie 61 59 5 5 0
UBQLN4 UBQLN4 Q9NRR5 Ubiquilin-4 chr1 Not Cancer Driver No 1 intact, hippie 70 561 67 67 1
UGGT1 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 169 161 20 20 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 intact, hippie 88 186 16 16 16
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 intact, hippie, biogrid 84 316 57 57 1
WDR73 WDR73 Q6P4I2 WD repeat-containing protein 73 chr15 Not Cancer Driver No 1 intact, hippie 29 86 7 7 0
ZBTB48 ZBTB48 P10074 Telomere zinc finger-associated protein chr1 Not Cancer Driver No 1 hippie 53 237 16 16 0