Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AAAS | AAAS | Q9NRG9 | Aladin | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 116 | 12 | 12 | 3 |
| ABCD1 | ABCD1 | P33897 | ATP-binding cassette sub-family D member 1 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 75 | 5 | 5 | 138 |
| ACAD9 | ACAD9 | Q9H845 | Complex I assembly factor ACAD9, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 28 | 5 | 5 | 12 |
| ADGRL3 | ADGRL3 | Q9HAR2 | Adhesion G protein-coupled receptor L3 | chr4 | Not Cancer Driver | No | 1 | hippie | 440 | 517 | 130 | 130 | 0 |
| AGPAT5 | AGPAT5 | Q9NUQ2 | 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 39 | 5 | 5 | 0 |
| ALG5 | ALG5 | Q9Y673 | Dolichyl-phosphate beta-glucosyltransferase | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 0 | 0 | 0 | 0 |
| ANKLE2 | ANKLE2 | Q86XL3 | Ankyrin repeat and LEM domain-containing protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 127 | 521 | 71 | 71 | 2 |
| APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | Not Cancer Driver | No | 1 | hippie | 34 | 103 | 14 | 14 | 0 |
| ARFGEF1 | ARFGEF1 | Q9Y6D6 | Brefeldin A-inhibited guanine nucleotide-exchange protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 243 | 456 | 54 | 54 | 0 |
| ARFGEF2 | ARFGEF2 | Q9Y6D5 | Brefeldin A-inhibited guanine nucleotide-exchange protein 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 254 | 358 | 63 | 63 | 0 |
| ATP13A2 | ATP13A2 | Q9NQ11 | Polyamine-transporting ATPase 13A2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 152 | 121 | 10 | 10 | 9 |
| ATP13A3_ENST00000256031 | ATP13A3 | Q9H7F0 | Polyamine-transporting ATPase 13A3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 149 | 49 | 11 | 11 | 0 |
| ATP1A3_ENST00000302102 | ATP1A3 | P13637 | Sodium/potassium-transporting ATPase subunit alpha-3 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 200 | 115 | 29 | 29 | 31 |
| ATP6V0C | ATP6V0C | P27449 | V-type proton ATPase 16 kDa proteolipid subunit c | chr16 | Not Cancer Driver | No | 1 | hippie | 19 | 1 | 0 | 0 | 0 |
| ATR | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | Census, Compendium | Yes | 1 | hippie, biogrid | 338 | 106 | 14 | 14 | 1 |
| AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 63 | 8 | 8 | 0 |
| B3GAT1_ENST00000312527 | B3GAT1 | Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 93 | 32 | 32 | 0 |
| BCAP31_ENST00000345046 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 104 | 14 | 14 | 0 |
| BNIP1_ENST00000351486 | BNIP1 | Q12981 | Vesicle transport protein SEC20 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 57 | 10 | 10 | 0 |
| C2CD2 | C2CD2 | Q9Y426 | C2 domain-containing protein 2 | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 385 | 56 | 56 | 0 |
| C2CD2L | C2CD2L | O14523 | Phospholipid transfer protein C2CD2L | chr11 | Not Cancer Driver | No | 1 | hippie | 77 | 491 | 65 | 65 | 0 |
| CA9 | CA9 | Q16790 | Carbonic anhydrase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 72 | 274 | 50 | 50 | 0 |
| CCDC107 | CCDC107 | Q8WV48 | Coiled-coil domain-containing protein 107 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 215 | 12 | 12 | 0 |
| CD1A | CD1A | P06126 | T-cell surface glycoprotein CD1a | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 105 | 18 | 6 | 6 | 0 |
| CD3E | CD3E | P07766 | T-cell surface glycoprotein CD3 epsilon chain | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 72 | 12 | 12 | 0 |
| CDC6 | CDC6 | Q99741 | Cell division control protein 6 homolog | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 170 | 15 | 15 | 1 |
| CKAP4 | CKAP4 | Q07065 | Cytoskeleton-associated protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 409 | 55 | 55 | 0 |
| CLCN3_ENST00000513761 | CLCN3 | P51790 | H(+)/Cl(-) exchange transporter 3 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 105 | 88 | 7 | 7 | 0 |
| CLCN4 | CLCN4 | P51793 | H(+)/Cl(-) exchange transporter 4 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 118 | 62 | 13 | 13 | 11 |
| CLCN5 | CLCN5 | P51795 | H(+)/Cl(-) exchange transporter 5 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 138 | 81 | 6 | 6 | 32 |
| CLDN1 | CLDN1 | O95832 | Claudin-1 | chr3 | Not Cancer Driver | No | 1 | hippie | 31 | 16 | 3 | 3 | 0 |
| CLDN10 | CLDN10 | P78369 | Claudin-10 | chr13 | Not Cancer Driver | No | 1 | hippie | 51 | 4 | 1 | 1 | 2 |
| CLEC2B | CLEC2B | Q92478 | C-type lectin domain family 2 member B | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 0 | 0 | 0 | 0 |
| CLEC2D_ENST00000290855 | CLEC2D | Q9UHP7 | C-type lectin domain family 2 member D | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 14 | 1 | 1 | 0 |
| CLEC4E | CLEC4E | Q9ULY5 | C-type lectin domain family 4 member E | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 5 | 2 | 2 | 0 |
| CXCR4_ENST00000241393 | CXCR4 | P61073 | C-X-C chemokine receptor type 4 | chr2 | Census, Compendium | Yes | 1 | hippie, biogrid | 62 | 5 | 1 | 1 | 0 |
| CYP2C18 | CYP2C18 | P33260 | Cytochrome P450 2C18 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 114 | 11 | 1 | 1 | 0 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 131 | 681 | 68 | 68 | 0 |
| DERL1 | DERL1 | Q9BUN8 | Derlin-1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 11 | 1 | 1 | 0 |
| DNM1 | DNM1 | Q05193 | Dynamin-1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 98 | 280 | 23 | 23 | 4 |
| DNM1L_ENST00000549701 | DNM1L | O00429 | Dynamin-1-like protein | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 212 | 23 | 23 | 7 |
| DNM2_ENST00000355667 | DNM2 | P50570 | Dynamin-2 | chr19 | Census | Yes | 1 | hippie, biogrid | 138 | 270 | 43 | 43 | 22 |
| DNM3_ENST00000355305 | DNM3 | Q9UQ16 | Dynamin-3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 166 | 257 | 45 | 45 | 0 |
| DSTYK | DSTYK | Q6XUX3 | Dual serine/threonine and tyrosine protein kinase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 112 | 112 | 4 | 4 | 2 |
| DUOXA2 | DUOXA2 | Q1HG44 | Dual oxidase maturation factor 2 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 0 | 0 | 0 | 0 |
| ECSIT | ECSIT | Q9BQ95 | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 146 | 29 | 29 | 0 |
| ELOVL5_ENST00000304434 | ELOVL5 | Q9NYP7 | Elongation of very long chain fatty acids protein 5 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 25 | 4 | 4 | 2 |
| EMD | EMD | P50402 | Emerin | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 160 | 28 | 28 | 4 |
| EMP1 | EMP1 | P54849 | Epithelial membrane protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 0 | 0 | 0 | 0 |
| EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 182 | 140 | 24 | 24 | 0 |
| ESYT2_ENST00000613624 | ESYT2 | A0FGR8 | Extended synaptotagmin-2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 94 | 376 | 25 | 25 | 0 |
| EYA2 | EYA2 | O00167 | Eyes absent homolog 2 | chr20 | Not Cancer Driver | No | 1 | hippie | 107 | 204 | 50 | 50 | 0 |
| FAM118B | FAM118B | Q9BPY3 | Protein FAM118B | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 37 | 4 | 4 | 0 |
| FAM8A1 | FAM8A1 | Q9UBU6 | Protein FAM8A1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 196 | 14 | 14 | 0 |
| FANCD2_ENST00000383807 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | Census, Compendium | Yes | 1 | hippie, biogrid | 176 | 181 | 14 | 14 | 3 |
| FASTKD1 | FASTKD1 | Q53R41 | FAST kinase domain-containing protein 1, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 125 | 0 | 0 | 0 | 0 |
| FASTKD3 | FASTKD3 | Q14CZ7 | FAST kinase domain-containing protein 3, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 6 | 1 | 1 | 0 |
| FEM1A | FEM1A | Q9BSK4 | Protein fem-1 homolog A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 162 | 22 | 22 | 0 |
| FLVCR1 | FLVCR1 | Q9Y5Y0 | Feline leukemia virus subgroup C receptor-related protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 117 | 14 | 14 | 4 |
| FZD7 | FZD7 | O75084 | Frizzled-7 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 22 | 2 | 2 | 0 |
| GALNT6_ENST00000356317 | GALNT6 | Q8NCL4 | Polypeptide N-acetylgalactosaminyltransferase 6 | chr12 | Not Cancer Driver | No | 1 | hippie | 105 | 117 | 26 | 26 | 0 |
| GATB | GATB | O75879 | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 79 | 138 | 26 | 26 | 0 |
| GBF1 | GBF1 | Q92538 | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 216 | 669 | 76 | 76 | 0 |
| GGA1 | GGA1 | Q9UJY5 | ADP-ribosylation factor-binding protein GGA1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 385 | 33 | 33 | 0 |
| GGCX | GGCX | P38435 | Vitamin K-dependent gamma-carboxylase | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 131 | 15 | 15 | 8 |
| GJA3 | GJA3 | Q9Y6H8 | Gap junction alpha-3 protein | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 211 | 13 | 13 | 20 |
| GJD3 | GJD3 | Q8N144 | Gap junction delta-3 protein | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 79 | 0 | 0 | 0 |
| GLS | GLS | O94925 | Glutaminase kidney isoform, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 187 | 9 | 9 | 3 |
| GOLGA5 | GOLGA5 | Q8TBA6 | Golgin subfamily A member 5 | chr14 | Census | Yes | 1 | hippie, biogrid | 89 | 591 | 62 | 62 | 0 |
| GOPC | GOPC | Q9HD26 | Golgi-associated PDZ and coiled-coil motif-containing protein | chr6 | Census | Yes | 1 | hippie, biogrid | 56 | 263 | 34 | 34 | 0 |
| GPD1L | GPD1L | Q8N335 | Glycerol-3-phosphate dehydrogenase 1-like protein | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 13 | 1 | 1 | 0 |
| GPR50 | GPR50 | Q13585 | Melatonin-related receptor | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 170 | 285 | 100 | 100 | 0 |
| GUF1 | GUF1 | Q8N442 | Translation factor GUF1, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 38 | 5 | 5 | 1 |
| HDHD5 | HDHD5 | Q9BXW7 | Haloacid dehalogenase-like hydrolase domain-containing 5 | chr22 | Not Cancer Driver | No | 1 | hippie | 47 | 49 | 6 | 6 | 0 |
| HEATR1 | HEATR1 | Q9H583 | HEAT repeat-containing protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 291 | 43 | 5 | 5 | 0 |
| HEATR6 | HEATR6 | Q6AI08 | HEAT repeat-containing protein 6 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 124 | 250 | 28 | 28 | 0 |
| HNRNPH1 | HNRNPH1 | P31943 | Heterogeneous nuclear ribonucleoprotein H | chr5 | Not Cancer Driver | No | 1 | hippie | 51 | 169 | 29 | 29 | 0 |
| HSD17B11 | HSD17B11 | Q8NBQ5 | Estradiol 17-beta-dehydrogenase 11 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 3 | 0 | 0 | 0 |
| HSD3B7 | HSD3B7 | Q9H2F3 | 3 beta-hydroxysteroid dehydrogenase type 7 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 27 | 5 | 5 | 2 |
| HSPA12A_ENST00000369209 | HSPA12A | O43301 | Heat shock 70 kDa protein 12A | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 130 | 86 | 16 | 16 | 0 |
| HUS1 | HUS1 | O60921 | Checkpoint protein HUS1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 17 | 2 | 2 | 0 |
| INTS2 | INTS2 | Q9H0H0 | Integrator complex subunit 2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 149 | 97 | 8 | 8 | 0 |
| INTS4 | INTS4 | Q96HW7 | Integrator complex subunit 4 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 117 | 82 | 7 | 7 | 0 |
| INTS7 | INTS7 | Q9NVH2 | Integrator complex subunit 7 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 88 | 17 | 17 | 0 |
| JAK1 | JAK1 | P23458 | Tyrosine-protein kinase JAK1 | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 147 | 120 | 7 | 7 | 2 |
| JPH1 | JPH1 | Q9HDC5 | Junctophilin-1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 131 | 421 | 89 | 89 | 0 |
| KCNN4 | KCNN4 | O15554 | Intermediate conductance calcium-activated potassium channel protein 4 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 31 | 6 | 6 | 3 |
| KIDINS220 | KIDINS220 | Q9ULH0 | Kinase D-interacting substrate of 220 kDa | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 245 | 683 | 113 | 113 | 0 |
| KLRD1 | KLRD1 | Q13241 | Natural killer cells antigen CD94 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 0 | 0 | 0 | 0 |
| KNTC1 | KNTC1 | P50748 | Kinetochore-associated protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 250 | 70 | 9 | 9 | 0 |
| KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 1 | hippie, biogrid | 788 | 7 | 2 | 2 | 27 |
| LDLRAD1 | LDLRAD1 | Q5T700 | Low-density lipoprotein receptor class A domain-containing protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 14 | 2 | 2 | 0 |
| LGALS3 | LGALS3 | P17931 | Galectin-3 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 133 | 6 | 6 | 0 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
| LNPK_ENST00000272748 | LNPK | Q9C0E8 | Endoplasmic reticulum junction formation protein lunapark | chr2 | Not Cancer Driver | No | 1 | hippie | 62 | 257 | 43 | 43 | 0 |
| LPAR1_ENST00000358883 | LPAR1 | Q92633 | Lysophosphatidic acid receptor 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 79 | 21 | 6 | 6 | 0 |
| LPCAT2 | LPCAT2 | Q7L5N7 | Lysophosphatidylcholine acyltransferase 2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 35 | 5 | 5 | 0 |
| LRRC59 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 122 | 15 | 15 | 0 |
| LTN1_ENST00000361371 | LTN1 | O94822 | E3 ubiquitin-protein ligase listerin | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 192 | 124 | 23 | 23 | 0 |
| MAD2L2 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 22 | 0 | 0 | 0 | 1 |
| MDN1 | MDN1 | Q9NU22 | Midasin | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 678 | 983 | 107 | 107 | 0 |
| METTL7A_ENST00000332160 | METTL7A | Q9H8H3 | Putative methyltransferase-like protein 7A | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 0 | 0 | 0 | 0 |
| MON2 | MON2 | Q7Z3U7 | Protein MON2 homolog | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 201 | 151 | 16 | 16 | 0 |
| MRPL12 | MRPL12 | P52815 | 39S ribosomal protein L12, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 22 | 6 | 6 | 1 |
| NDC1 | NDC1 | Q9BTX1 | Nucleoporin NDC1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 92 | 12 | 12 | 0 |
| NDUFAF1 | NDUFAF1 | Q9Y375 | Complex I intermediate-associated protein 30, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 63 | 8 | 8 | 4 |
| NEK6_ENST00000545174 | NEK6 | Q9HC98 | Serine/threonine-protein kinase Nek6 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 36 | 0 | 0 | 0 |
| NEK7 | NEK7 | Q8TDX7 | Serine/threonine-protein kinase Nek7 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 23 | 0 | 0 | 0 |
| NINJ2 | NINJ2 | A0A590UJR9 | Ninjurin 2, isoform CRA_a | chr12 | Not Cancer Driver | No | 1 | hippie | 17 | 67 | 5 | 5 | 0 |
| NOCT | NOCT | Q9UK39 | Nocturnin | chr4 | Not Cancer Driver | No | 1 | hippie | 33 | 89 | 3 | 3 | 0 |
| NOP9 | NOP9 | Q86U38 | Nucleolar protein 9 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 166 | 14 | 14 | 0 |
| NRAS | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 284 | 10 | 0 | 0 | 14 |
| NUBPL | NUBPL | Q8TB37 | Iron-sulfur protein NUBPL | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 49 | 1 | 1 | 2 |
| NUP205 | NUP205 | Q92621 | Nuclear pore complex protein Nup205 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 251 | 101 | 16 | 16 | 1 |
| OGFOD3_ENST00000313056 | OGFOD3 | Q6PK18 | 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 51 | 5 | 5 | 0 |
| OMA1 | OMA1 | Q96E52 | Metalloendopeptidase OMA1, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 34 | 4 | 4 | 0 |
| OPA3_ENST00000263275 | OPA3 | Q9H6K4 | Optic atrophy 3 protein | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 44 | 7 | 7 | 2 |
| OSBPL8 | OSBPL8 | Q9BZF1 | Oxysterol-binding protein-related protein 8 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 105 | 401 | 37 | 37 | 0 |
| OXCT1 | OXCT1 | P55809 | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 39 | 5 | 5 | 11 |
| OXSR1 | OXSR1 | O95747 | Serine/threonine-protein kinase OSR1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 208 | 29 | 29 | 0 |
| PCDHB3 | PCDHB3 | Q9Y5E6 | Protocadherin beta-3 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 258 | 119 | 30 | 30 | 0 |
| PDS5A | PDS5A | Q29RF7 | Sister chromatid cohesion protein PDS5 homolog A | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 150 | 295 | 34 | 34 | 0 |
| PDS5B | PDS5B | Q9NTI5 | Sister chromatid cohesion protein PDS5 homolog B | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 174 | 455 | 61 | 61 | 0 |
| PDXDC1 | PDXDC1 | Q6P996 | Pyridoxal-dependent decarboxylase domain-containing protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 272 | 29 | 29 | 0 |
| PGAP2_ENST00000463452 | PGAP2 | Q9UHJ9 | Post-GPI attachment to proteins factor 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 38 | 0 | 0 | 0 | 5 |
| PIGN_ENST00000638936 | PIGN | O95427 | GPI ethanolamine phosphate transferase 1 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 23 | 2 | 2 | 1 |
| PKMYT1 | PKMYT1 | Q99640 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 228 | 19 | 19 | 0 |
| PPT1 | PPT1 | P50897 | Palmitoyl-protein thioesterase 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 0 | 0 | 0 | 23 |
| PPTC7 | PPTC7 | Q8NI37 | Protein phosphatase PTC7 homolog | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 36 | 2 | 2 | 0 |
| PRDX2 | PRDX2 | P32119 | Peroxiredoxin-2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 30 | 4 | 4 | 0 |
| PRKAG1_ENST00000548065 | PRKAG1 | P54619 | 5'-AMP-activated protein kinase subunit gamma-1 | chr12 | Not Cancer Driver | No | 1 | hippie | 35 | 25 | 2 | 2 | 0 |
| PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 140 | 25 | 25 | 0 |
| RAB29 | RAB29 | O14966 | Ras-related protein Rab-7L1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 18 | 3 | 3 | 0 |
| RAB3B | RAB3B | P20337 | Ras-related protein Rab-3B | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 36 | 25 | 6 | 6 | 0 |
| RAB5C_ENST00000393860 | RAB5C | P51148 | Ras-related protein Rab-5C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 50 | 4 | 4 | 0 |
| RAB9A | RAB9A | P51151 | Ras-related protein Rab-9A | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 21 | 1 | 1 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
| RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
| RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 4 |
| RAD51C | RAD51C | O43502 | DNA repair protein RAD51 homolog 3 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 18 | 2 | 2 | 6 |
| RANBP6 | RANBP6 | O60518 | Ran-binding protein 6 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 152 | 46 | 4 | 4 | 0 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
| RHOBTB3 | RHOBTB3 | O94955 | Rho-related BTB domain-containing protein 3 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 34 | 2 | 2 | 0 |
| RHOC_ENST00000369642 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 53 | 7 | 7 | 0 |
| RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
| RHOU | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 63 | 6 | 6 | 0 |
| RIF1 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 287 | 1355 | 164 | 164 | 0 |
| RINT1 | RINT1 | Q6NUQ1 | RAD50-interacting protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 55 | 3 | 3 | 2 |
| RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
| RPN1 | RPN1 | P04843 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | chr3 | Census | Yes | 1 | hippie, biogrid | 50 | 69 | 3 | 3 | 0 |
| RPN2 | RPN2 | P04844 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 26 | 4 | 4 | 0 |
| RSPH14 | RSPH14 | Q9UHP6 | Radial spoke head 14 homolog | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 15 | 1 | 1 | 0 |
| S100A16_ENST00000368703 | S100A16 | Q96FQ6 | Protein S100-A16 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 21 | 1 | 1 | 0 |
| SACM1L | SACM1L | Q9NTJ5 | Phosphatidylinositol-3-phosphatase SAC1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 0 | 0 | 0 | 0 |
| SEC61B | SEC61B | P60468 | Protein transport protein Sec61 subunit beta | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 11 | 60 | 7 | 7 | 0 |
| SEC62 | SEC62 | Q99442 | Translocation protein SEC62 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 211 | 23 | 23 | 0 |
| SLC12A6_ENST00000558667 | SLC12A6 | Q9UHW9 | Solute carrier family 12 member 6 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 168 | 280 | 46 | 46 | 0 |
| SLC1A1 | SLC1A1 | P43005 | Excitatory amino acid transporter 3 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 17 | 4 | 4 | 1 |
| SLC20A1 | SLC20A1 | Q8WUM9 | Sodium-dependent phosphate transporter 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 157 | 9 | 9 | 0 |
| SLC25A19_ENST00000416858 | SLC25A19 | Q9HC21 | Mitochondrial thiamine pyrophosphate carrier | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 16 | 0 | 0 | 2 |
| SLC25A29 | SLC25A29 | Q8N8R3 | Mitochondrial basic amino acids transporter | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 9 | 22 | 0 | 0 | 0 |
| SLC25A4 | SLC25A4 | P12235 | ADP/ATP translocase 1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 0 | 0 | 0 | 9 |
| SLC27A3_ENST00000271857 | SLC27A3 | X6R3N0 | Solute carrier family 27 (Fatty acid transporter), member 3, isoform CRA_d | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 171 | 16 | 16 | 0 |
| SLC30A8 | SLC30A8 | Q8IWU4 | Zinc transporter 8 | chr8 | Not Cancer Driver | No | 1 | hippie | 115 | 25 | 9 | 9 | 0 |
| SORT1 | SORT1 | Q99523 | Sortilin | chr1 | Not Cancer Driver | No | 1 | hippie | 69 | 110 | 2 | 2 | 0 |
| SPRTN | SPRTN | Q9H040 | DNA-dependent metalloprotease SPRTN | chr1 | Not Cancer Driver | No | 1 | hippie | 73 | 252 | 38 | 38 | 1 |
| SSR1 | SSR1 | P43307 | Translocon-associated protein subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 114 | 10 | 10 | 0 |
| ST7 | ST7 | Q9NRC1 | Suppressor of tumorigenicity 7 protein | chr7 | Not Cancer Driver | No | 1 | hippie | 62 | 64 | 5 | 5 | 0 |
| STEAP3_ENST00000393107 | STEAP3 | Q658P3 | Metalloreductase STEAP3 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 30 | 2 | 2 | 0 |
| STX10 | STX10 | O60499 | Syntaxin-10 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 77 | 7 | 7 | 0 |
| STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 152 | 20 | 20 | 0 |
| STX5 | STX5 | Q13190 | Syntaxin-5 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 147 | 14 | 14 | 0 |
| STX6 | STX6 | O43752 | Syntaxin-6 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 33 | 78 | 11 | 11 | 0 |
| STX7 | STX7 | O15400 | Syntaxin-7 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 164 | 14 | 14 | 0 |
| SYVN1 | SYVN1 | Q86TM6 | E3 ubiquitin-protein ligase synoviolin | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 284 | 32 | 32 | 0 |
| TAMM41_ENST00000444133 | TAMM41 | Q96BW9 | Phosphatidate cytidylyltransferase, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 21 | 0 | 0 | 0 |
| TAP1 | TAP1 | Q03518-2 | Isoform 2 of Antigen peptide transporter 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 83 | 6 | 6 | 0 |
| TBRG4_ENST00000494076 | TBRG4 | Q969Z0 | FAST kinase domain-containing protein 4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 60 | 2 | 2 | 0 |
| TFB2M | TFB2M | Q9H5Q4 | Dimethyladenosine transferase 2, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 36 | 6 | 6 | 0 |
| TM2D3 | TM2D3 | Q9BRN9 | TM2 domain-containing protein 3 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 13 | 3 | 3 | 0 |
| TM9SF2 | TM9SF2 | Q99805 | Transmembrane 9 superfamily member 2 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 16 | 2 | 2 | 0 |
| TMEM140 | TMEM140 | Q9NV12 | Transmembrane protein 140 | chr7 | Not Cancer Driver | No | 1 | hippie | 24 | 1 | 0 | 0 | 0 |
| TMEM17 | TMEM17 | Q86X19 | Transmembrane protein 17 | chr2 | Not Cancer Driver | No | 1 | hippie | 22 | 14 | 2 | 2 | 0 |
| TMEM216 | TMEM216 | Q9P0N5 | Transmembrane protein 216 | chr11 | Not Cancer Driver | No | 1 | hippie | 11 | 0 | 0 | 0 | 7 |
| TMEM230_ENST00000379286 | TMEM230 | Q96A57 | Transmembrane protein 230 | chr20 | Not Cancer Driver | No | 1 | hippie | 23 | 0 | 0 | 0 | 0 |
| TMEM60 | TMEM60 | Q9H2L4 | Transmembrane protein 60 | chr7 | Not Cancer Driver | No | 1 | hippie | 13 | 0 | 0 | 0 | 0 |
| TMEM97 | TMEM97 | Q5BJF2 | Sigma intracellular receptor 2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 0 | 0 | 0 | 0 |
| TMEM9B | TMEM9B | Q9NQ34 | Transmembrane protein 9B | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 0 | 0 | 0 | 0 |
| TNFAIP2_ENST00000333007 | TNFAIP2 | Q03169 | Tumor necrosis factor alpha-induced protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 152 | 4 | 4 | 0 |
| TNFSF8 | TNFSF8 | P32971 | Tumor necrosis factor ligand superfamily member 8 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 30 | 2 | 2 | 0 |
| TPCN1_ENST00000335509 | TPCN1 | Q9ULQ1 | Two pore channel protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 114 | 99 | 18 | 18 | 0 |
| TRARG1 | TRARG1 | Q8IXB3 | Trafficking regulator of GLUT4 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 33 | 83 | 11 | 11 | 0 |
| TRDN | TRDN | Q13061 | Triadin | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 129 | 639 | 102 | 102 | 1 |
| TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
| TSC2 | TSC2 | P49815 | Tuberin | chr16 | Census, Compendium | Yes | 1 | hippie, biogrid | 192 | 563 | 50 | 50 | 53 |
| TSPO_ENST00000329563 | TSPO | P30536 | Translocator protein | chr22 | Not Cancer Driver | No | 1 | hippie | 5 | 1 | 0 | 0 | 0 |
| TTC27 | TTC27 | Q6P3X3 | Tetratricopeptide repeat protein 27 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 109 | 40 | 5 | 5 | 0 |
| TUBB3 | TUBB3 | Q13509 | Tubulin beta-3 chain | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 53 | 10 | 10 | 12 |
| TUBGCP4 | TUBGCP4 | Q9UGJ1 | Gamma-tubulin complex component 4 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 79 | 62 | 5 | 5 | 0 |
| TVP23C_ENST00000518321 | TVP23C | Q96ET8-3 | Isoform 3 of Golgi apparatus membrane protein TVP23 homolog C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 16 | 1 | 1 | 0 |
| UBE3C | UBE3C | Q15386 | Ubiquitin-protein ligase E3C | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 143 | 65 | 12 | 12 | 0 |
| UCKL1 | UCKL1 | Q9NWZ5 | Uridine-cytidine kinase-like 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 134 | 15 | 15 | 0 |
| UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 109 | 141 | 24 | 24 | 0 |
| UGDH_ENST00000506179 | UGDH | O60701 | UDP-glucose 6-dehydrogenase | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 39 | 4 | 4 | 5 |
| UQCC1 | UQCC1 | Q9NVA1 | Ubiquinol-cytochrome-c reductase complex assembly factor 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 59 | 10 | 10 | 0 |
| VMA21 | VMA21 | Q3ZAQ7 | Vacuolar ATPase assembly integral membrane protein VMA21 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 7 | 1 | 1 | 0 |
| VMP1 | VMP1 | Q96GC9 | Vacuole membrane protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 68 | 11 | 11 | 0 |
| VPS29_ENST00000549578 | VPS29 | Q9UBQ0 | Vacuolar protein sorting-associated protein 29 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 0 | 0 | 0 | 0 |
| VPS50 | VPS50 | Q96JG6 | Syndetin | chr7 | Not Cancer Driver | No | 1 | hippie | 175 | 171 | 32 | 32 | 0 |
| VPS52 | VPS52 | Q8N1B4 | Vacuolar protein sorting-associated protein 52 homolog | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 89 | 36 | 5 | 5 | 0 |
| VPS53 | VPS53 | Q5VIR6 | Vacuolar protein sorting-associated protein 53 homolog | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 172 | 27 | 27 | 1 |
| VTI1A | VTI1A | Q96AJ9 | Vesicle transport through interaction with t-SNAREs homolog 1A | chr10 | Census | Yes | 1 | hippie, biogrid | 21 | 138 | 13 | 13 | 0 |
| WFS1_ENST00000503569 | WFS1 | O76024 | Wolframin | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 105 | 203 | 10 | 10 | 39 |
| XPO5 | XPO5 | Q9HAV4 | Exportin-5 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 112 | 64 | 7 | 7 | 0 |
| XPR1 | XPR1 | Q9UBH6 | Xenotropic and polytropic retrovirus receptor 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 103 | 70 | 15 | 15 | 4 |
| ZDHHC13 | ZDHHC13 | Q8IUH4 | Palmitoyltransferase ZDHHC13 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 27 | 1 | 1 | 0 |
| ZDHHC17 | ZDHHC17 | Q8IUH5 | Palmitoyltransferase ZDHHC17 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 49 | 9 | 9 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|