Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALK | ALK | Q9UM73 | ALK tyrosine kinase receptor | chr2 | Census, Compendium | Yes | 1 | intact | 303 | 575 | 114 | 114 | 16 |
| APBA3 | APBA3 | O96018 | Amyloid-beta A4 precursor protein-binding family A member 3 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 306 | 43 | 43 | 0 |
| APLNR | APLNR | P35414 | Apelin receptor | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 96 | 29 | 8 | 8 | 0 |
| ATP2A1 | ATP2A1 | O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 80 | 11 | 11 | 1 |
| ATP2A3_ENST00000397041 | ATP2A3 | Q93084 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 130 | 147 | 16 | 16 | 0 |
| B3GNT3_ENST00000595387 | B3GNT3 | Q9Y2A9 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 44 | 6 | 6 | 0 |
| B4GAT1 | B4GAT1 | O43505 | Beta-1,4-glucuronyltransferase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 4 | 0 | 0 | 2 |
| BICD2_ENST00000375512 | BICD2 | Q8TD16 | Protein bicaudal D homolog 2 | chr9 | Not Cancer Driver | No | 1 | hippie | 115 | 546 | 73 | 73 | 10 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
| CA9 | CA9 | Q16790 | Carbonic anhydrase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 72 | 274 | 50 | 50 | 0 |
| CGRRF1 | CGRRF1 | Q99675 | Cell growth regulator with RING finger domain protein 1 | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 31 | 34 | 5 | 5 | 0 |
| CHRNA1_ENST00000348749 | CHRNA1 | P02708 | Acetylcholine receptor subunit alpha | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 9 | 1 | 1 | 12 |
| CIC | CIC | Q96RK0 | Protein capicua homolog | chr19 | Census, Compendium | Yes | 1 | hippie | 276 | 1550 | 266 | 266 | 0 |
| CLEC17A | CLEC17A | Q6ZS10 | C-type lectin domain family 17, member A | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 77 | 162 | 45 | 45 | 0 |
| CPLX4 | CPLX4 | Q7Z7G2 | Complexin-4 | chr18 | Not Cancer Driver | No | 1 | hippie | 36 | 142 | 33 | 33 | 0 |
| CRELD1_ENST00000383811 | CRELD1 | Q96HD1 | Protein disulfide isomerase CRELD1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 44 | 7 | 7 | 4 |
| CXCR4_ENST00000241393 | CXCR4 | P61073 | C-X-C chemokine receptor type 4 | chr2 | Census, Compendium | Yes | 1 | hippie, biogrid | 62 | 5 | 1 | 1 | 0 |
| CYB5R3_ENST00000352397 | CYB5R3 | P00387 | NADH-cytochrome b5 reductase 3 | chr22 | Not Cancer Driver | No | 1 | hippie | 42 | 24 | 3 | 3 | 9 |
| CYP19A1_ENST00000396404 | CYP19A1 | P11511 | Aromatase | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 91 | 2 | 1 | 1 | 5 |
| DERL1 | DERL1 | Q9BUN8 | Derlin-1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 11 | 1 | 1 | 0 |
| DNAJC1 | DNAJC1 | Q96KC8 | DnaJ homolog subfamily C member 1 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 60 | 315 | 44 | 44 | 0 |
| DNAJC25 | DNAJC25 | Q9H1X3 | DnaJ homolog subfamily C member 25 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 39 | 3 | 3 | 0 |
| EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
| EMD | EMD | P50402 | Emerin | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 42 | 160 | 28 | 28 | 4 |
| ENTPD2 | ENTPD2 | Q9Y5L3 | Ectonucleoside triphosphate diphosphohydrolase 2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 32 | 0 | 0 | 0 |
| EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 334 | 1790 | 196 | 196 | 1 |
| ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
| EVA1B | EVA1B | Q9NVM1 | Protein eva-1 homolog B | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 118 | 9 | 9 | 0 |
| FANCD2_ENST00000383807 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | Census, Compendium | Yes | 1 | hippie | 176 | 181 | 14 | 14 | 3 |
| FATE1 | FATE1 | Q969F0 | Fetal and adult testis-expressed transcript protein | chrX | Not Cancer Driver | No | 1 | hippie | 45 | 117 | 30 | 30 | 0 |
| FBXO6 | FBXO6 | Q9NRD1 | F-box only protein 6 | chr1 | Not Cancer Driver | No | 1 | hippie | 31 | 27 | 3 | 3 | 0 |
| FRMD3 | FRMD3 | A2A2Y4 | FERM domain-containing protein 3 | chr9 | Not Cancer Driver | No | 1 | hippie | 110 | 131 | 27 | 27 | 0 |
| FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 184 | 30 | 30 | 0 |
| GABRD | GABRD | O14764 | Gamma-aminobutyric acid receptor subunit delta | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 19 | 5 | 5 | 1 |
| GFAP_ENST00000588735 | GFAP | P14136 | Glial fibrillary acidic protein | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 288 | 42 | 42 | 62 |
| GP9 | GP9 | P14770 | Platelet glycoprotein IX | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 0 | 0 | 0 | 7 |
| GPR152 | GPR152 | Q8TDT2 | Probable G-protein coupled receptor 152 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 55 | 172 | 27 | 27 | 0 |
| GPR182 | GPR182 | O15218 | G-protein coupled receptor 182 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 33 | 4 | 4 | 0 |
| GPR55 | GPR55 | Q9Y2T6 | G-protein coupled receptor 55 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 0 | 0 | 0 | 0 |
| GPRC5B_ENST00000569479 | GPRC5B | Q9NZH0 | G-protein coupled receptor family C group 5 member B | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 75 | 19 | 19 | 0 |
| HHIPL1 | HHIPL1 | Q96JK4 | HHIP-like protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 161 | 9 | 9 | 0 |
| HLA-DPA1 | HLA-DPA1 | P20036 | HLA class II histocompatibility antigen, DP alpha 1 chain | chr6 | Not Cancer Driver | No | 3 | hippie, biogrid | 37 | 30 | 4 | 4 | 0 |
| HLA-DQA1 | HLA-DQA1 | A0A173ADG5 | HLA class II histocompatibility antigen DQ alpha chain | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 5 | 0 | 0 | 0 |
| HLA-DRB1 | HLA-DRB1 | P01911 | HLA class II histocompatibility antigen, DRB1 beta chain | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 12 | 1 | 1 | 0 |
| HSD3B7 | HSD3B7 | Q9H2F3 | 3 beta-hydroxysteroid dehydrogenase type 7 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 27 | 5 | 5 | 2 |
| KCNE3 | KCNE3 | Q9Y6H6 | Potassium voltage-gated channel subfamily E member 3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 24 | 2 | 2 | 0 |
| KCNG4 | KCNG4 | Q8TDN1 | Potassium voltage-gated channel subfamily G member 4 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 117 | 47 | 10 | 10 | 0 |
| KCNJ9 | KCNJ9 | Q92806 | G protein-activated inward rectifier potassium channel 3 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 47 | 67 | 1 | 1 | 0 |
| LGR4 | LGR4 | Q9BXB1 | Leucine-rich repeat-containing G-protein coupled receptor 4 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 16 | 3 | 3 | 0 |
| LHFPL5_ENST00000645222 | LHFPL5 | Q8TAF8 | LHFPL tetraspan subfamily member 5 protein | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 51 | 1 | 0 | 0 | 4 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
| LMNA | LMNA | P02545 | Prelamin-A/C | chr1 | Census | Yes | 2 | hippie, biogrid | 68 | 544 | 49 | 49 | 131 |
| LRRC25_ENST00000595840 | LRRC25 | Q8N386 | Leucine-rich repeat-containing protein 25 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 40 | 89 | 14 | 14 | 0 |
| LRRC59 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 122 | 15 | 15 | 0 |
| METTL7A_ENST00000332160 | METTL7A | Q9H8H3 | Putative methyltransferase-like protein 7A | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 0 | 0 | 0 | 0 |
| MFF | MFF | Q9GZY8 | Mitochondrial fission factor | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 59 | 264 | 47 | 47 | 0 |
| MINAR1 | MINAR1 | Q9UPX6 | Major intrinsically disordered Notch2-binding receptor 1 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 171 | 584 | 104 | 104 | 0 |
| MUSK | MUSK | O15146 | Muscle, skeletal receptor tyrosine-protein kinase | chr9 | Not Cancer Driver | No | 1 | intact | 188 | 35 | 7 | 7 | 7 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
| NDUFAF2 | NDUFAF2 | Q8N183 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 21 | 116 | 13 | 13 | 0 |
| NUAK1 | NUAK1 | O60285 | NUAK family SNF1-like kinase 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 142 | 357 | 77 | 77 | 0 |
| NUP155 | NUP155 | O75694 | Nuclear pore complex protein Nup155 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 154 | 221 | 19 | 19 | 1 |
| NUP35 | NUP35 | Q8NFH5 | Nucleoporin NUP35 | chr2 | Not Cancer Driver | No | 1 | hippie | 39 | 209 | 27 | 27 | 0 |
| OS9 | OS9 | Q13438 | Protein OS-9 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 451 | 49 | 49 | 0 |
| OTULINL | OTULINL | Q9NUU6 | Inactive ubiquitin thioesterase OTULINL | chr5 | Not Cancer Driver | No | 1 | hippie | 59 | 21 | 0 | 0 | 0 |
| P2RY8 | P2RY8 | Q86VZ1 | P2Y purinoceptor 8 | chrX | Census, Compendium | Yes | 1 | hippie, biogrid | 126 | 23 | 5 | 5 | 0 |
| PCDHB3 | PCDHB3 | Q9Y5E6 | Protocadherin beta-3 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 258 | 119 | 30 | 30 | 0 |
| PCDHB7 | PCDHB7 | Q9Y5E2 | Protocadherin beta-7 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 354 | 128 | 58 | 58 | 0 |
| PIGH | PIGH | Q14442 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit H | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 1 | 0 | 0 | 1 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PROKR1 | PROKR1 | Q8TCW9 | Prokineticin receptor 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 0 | 0 | 0 | 0 |
| PTPN5 | PTPN5 | P54829 | Tyrosine-protein phosphatase non-receptor type 5 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 101 | 163 | 32 | 32 | 0 |
| PXMP2 | PXMP2 | Q9NR77 | Peroxisomal membrane protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 0 | 0 | 0 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 1 | biogrid | 27 | 11 | 0 | 0 | 4 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
| RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 10 | 0 | 0 | 0 |
| RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
| RIPK4_ENST00000352483 | RIPK4 | P57078 | Receptor-interacting serine/threonine-protein kinase 4 | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 119 | 232 | 34 | 34 | 3 |
| RNF183_ENST00000297894 | RNF183 | Q96D59 | E3 ubiquitin-protein ligase RNF183 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 29 | 1 | 1 | 0 |
| RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
| RPN1 | RPN1 | P04843 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | chr3 | Census | Yes | 1 | hippie, biogrid | 50 | 69 | 3 | 3 | 0 |
| RPN2 | RPN2 | P04844 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 26 | 4 | 4 | 0 |
| SCAP | SCAP | Q12770 | Sterol regulatory element-binding protein cleavage-activating protein | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 145 | 329 | 36 | 36 | 0 |
| SEC61B | SEC61B | P60468 | Protein transport protein Sec61 subunit beta | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 60 | 7 | 7 | 0 |
| SEC62 | SEC62 | Q99442 | Translocation protein SEC62 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 211 | 23 | 23 | 0 |
| SLC16A11 | SLC16A11 | Q8NCK7 | Monocarboxylate transporter 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 33 | 72 | 5 | 5 | 0 |
| SLC26A6 | SLC26A6 | Q9BXS9 | Solute carrier family 26 member 6 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 68 | 87 | 13 | 13 | 0 |
| SLC39A4 | SLC39A4 | Q6P5W5 | Zinc transporter ZIP4 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 116 | 11 | 11 | 9 |
| SSR1 | SSR1 | P43307 | Translocon-associated protein subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 114 | 10 | 10 | 0 |
| ST7 | ST7 | Q9NRC1 | Suppressor of tumorigenicity 7 protein | chr7 | Not Cancer Driver | No | 1 | hippie | 62 | 64 | 5 | 5 | 0 |
| STAU1 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 77 | 456 | 63 | 63 | 0 |
| STIM1_ENST00000300737 | STIM1 | Q13586 | Stromal interaction molecule 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 387 | 45 | 45 | 13 |
| STX18 | STX18 | Q9P2W9 | Syntaxin-18 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 174 | 15 | 15 | 0 |
| STYK1 | STYK1 | Q6J9G0 | Tyrosine-protein kinase STYK1 | chr12 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 83 | 35 | 10 | 10 | 0 |
| SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 10 | 76 | 7 | 7 | 0 |
| SYNE3 | SYNE3 | Q6ZMZ3 | Nesprin-3 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 143 | 236 | 42 | 42 | 0 |
| SYNPO | SYNPO | Q8N3V7 | Synaptopodin | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 103 | 918 | 102 | 102 | 0 |
| TMEM237 | TMEM237 | Q96Q45 | Transmembrane protein 237 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 47 | 177 | 19 | 19 | 0 |
| TMEM268_ENST00000288502 | TMEM268 | Q5VZI3 | Transmembrane protein 268 | chr9 | Not Cancer Driver | No | 1 | hippie | 34 | 84 | 10 | 10 | 0 |
| TMEM35A | TMEM35A | Q53FP2 | Novel acetylcholine receptor chaperone | chrX | Not Cancer Driver | No | 1 | intact, hippie | 38 | 23 | 8 | 8 | 0 |
| TMPO | TMPO | P42166 | Lamina-associated polypeptide 2, isoform alpha | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 412 | 52 | 52 | 0 |
| TMX2 | TMX2 | Q9Y320 | Thioredoxin-related transmembrane protein 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 47 | 40 | 5 | 5 | 3 |
| TSPAN15 | TSPAN15 | O95858 | Tetraspanin-15 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 0 | 0 | 0 | 0 |
| UBAC2 | UBAC2 | Q8NBM4 | Ubiquitin-associated domain-containing protein 2 | chr13 | Not Cancer Driver | No | 1 | hippie | 33 | 57 | 9 | 9 | 0 |
| VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 186 | 16 | 16 | 16 |
| VEZT | VEZT | Q9HBM0 | Vezatin | chr12 | Not Cancer Driver | No | 1 | hippie | 83 | 278 | 22 | 22 | 0 |
| VIPR1 | VIPR1 | P32241 | Vasoactive intestinal polypeptide receptor 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 10 | 2 | 2 | 0 |
| ZDHHC12 | ZDHHC12 | Q96GR4 | Palmitoyltransferase ZDHHC12 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 13 | 1 | 1 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|