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THBS3 ,THBS3 ,P49746
  • Uniprot Accession= P49746
  • Ensembl Transcript= ENST00000368378.7
  • Uniprot Name= THBS3
  • Name= Thrombospondin-3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 36
  • Number of Interaction partner in biogrid: 66
  • Number of Interaction partner in hippie: 73
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 105 399 58 58 0
ARHGEF1_ENST00000354532 ARHGEF1 Q92888 Rho guanine nucleotide exchange factor 1 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 127 457 67 67 0
ASCC3 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 279 87 8 8 0
BBS2 BBS2 Q9BXC9 Bardet-Biedl syndrome 2 protein chr16 Not Cancer Driver No 1 hippie, biogrid 90 76 16 16 20
BBS7 BBS7 Q8IWZ6 Bardet-Biedl syndrome 7 protein chr4 Not Cancer Driver No 1 hippie, biogrid 99 56 8 8 4
BDH1 BDH1 Q02338 D-beta-hydroxybutyrate dehydrogenase, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 44 15 1 1 0
BLVRA BLVRA P53004 Biliverdin reductase A chr7 Not Cancer Driver No 3 intact, hippie, biogrid 34 6 1 1 0
BORA_ENST00000377815 BORA Q6PGQ7-2 Isoform 2 of Protein aurora borealis chr13 Not Cancer Driver No 1 hippie, biogrid 55 323 35 35 0
C5orf34 C5orf34 Q96MH7 Uncharacterized protein C5orf34 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 67 107 15 15 0
CALR CALR P27797 Calreticulin chr19 Census Yes 1 hippie 45 245 31 31 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 1 intact, hippie, biogrid 63 46 3 3 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 hippie, biogrid 59 36 6 6 0
CCZ1 CCZ1 P86791 Vacuolar fusion protein CCZ1 homolog chr7 Not Cancer Driver No 3 hippie, biogrid 40 43 3 3 0
CCZ1B CCZ1B P86790 Vacuolar fusion protein CCZ1 homolog B chr7 Not Cancer Driver No 1 intact 41 43 4 4 0
CORO7 CORO7 P57737 Coronin-7 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 108 347 38 38 0
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 368 73 22 22 140
CWF19L1 CWF19L1 Q69YN2 CWF19-like protein 1 chr10 Not Cancer Driver No 2 hippie, biogrid 59 69 9 9 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 154 280 55 55 1
DIP2A DIP2A Q14689 Disco-interacting protein 2 homolog A chr21 Not Cancer Driver No 3 intact, hippie, biogrid 204 396 53 53 0
DLST DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 Not Cancer Driver No 1 intact, hippie 53 190 32 32 1
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 50 152 21 21 0
DNM3_ENST00000355305 DNM3 Q9UQ16 Dynamin-3 chr1 Not Cancer Driver No 1 hippie, biogrid 166 257 45 45 0
EEF1AKNMT METTL13 Q8N6R0 eEF1A lysine and N-terminal methyltransferase chr1 Not Cancer Driver No 1 biogrid 91 76 16 16 0
FANCB FANCB Q8NB91 Fanconi anemia group B protein chrX Not Cancer Driver No 3 intact, hippie, biogrid 109 24 5 5 0
FDXR_ENST00000293195 FDXR P22570 NADPH:adrenodoxin oxidoreductase, mitochondrial chr17 Not Cancer Driver No 3 intact, hippie, biogrid 68 102 14 14 4
GTPBP6 GTPBP6 O43824 Putative GTP-binding protein 6 chrX Not Cancer Driver No 2 hippie, biogrid 32 117 0 0 0
HASPIN HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 Not Cancer Driver No 1 intact, hippie 87 373 36 36 0
HPS3 HPS3 Q969F9 Hermansky-Pudlak syndrome 3 protein chr3 Not Cancer Driver No 1 hippie, biogrid 124 51 10 10 1
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie, biogrid 61 82 6 6 2
INTS11_ENST00000435064 INTS11 Q5TA45 Integrator complex subunit 11 chr1 Not Cancer Driver No 1 hippie 64 24 2 2 0
IQSEC2_ENST00000396435 IQSEC2 Q5JU85 IQ motif and SEC7 domain-containing protein 2 chrX Not Cancer Driver No 3 intact, hippie, biogrid 163 1139 97 97 5
LRWD1 LRWD1 Q9UFC0 Leucine-rich repeat and WD repeat-containing protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 75 133 17 17 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 104 333 66 66 6
MCM9_ENST00000619706 MCM9 Q9NXL9 DNA helicase MCM9 chr6 Not Cancer Driver No 3 hippie, biogrid 56 523 13 13 0
MKS1 MKS1 Q9NXB0 Meckel syndrome type 1 protein chr17 Not Cancer Driver No 3 intact, hippie, biogrid 82 152 23 23 2
MTO1_ENST00000370300 MTO1 Q9Y2Z2 Protein MTO1 homolog, mitochondrial chr6 Not Cancer Driver No 3 hippie, biogrid 70 61 2 2 1
MTPAP MTPAP Q9NVV4 Poly(A) RNA polymerase, mitochondrial chr10 Not Cancer Driver No 3 intact, hippie, biogrid 73 136 22 22 1
NDUFA3 NDUFA3 O95167 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 chr19 Not Cancer Driver No 1 hippie, biogrid 7 27 4 4 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 Not Cancer Driver No 1 intact, hippie 35 23 0 0 0
NOL11 NOL11 Q9H8H0 Nucleolar protein 11 chr17 Not Cancer Driver No 1 hippie, biogrid 76 54 9 9 0
NSUN2 NSUN2 Q08J23 RNA cytosine C(5)-methyltransferase NSUN2 chr5 Not Cancer Driver No 1 hippie, biogrid 112 221 21 21 1
PC PC P11498 Pyruvate carboxylase, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 185 172 27 27 9
PCCA PCCA P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 102 42 14 14 16
PDE7A PDE7A Q13946 High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A chr8 Not Cancer Driver No 3 intact, hippie, biogrid 49 30 7 7 0
PEX1 PEX1 O43933 Peroxisome biogenesis factor 1 chr7 Not Cancer Driver No 1 hippie, biogrid 143 304 36 36 14
PEX6 PEX6 Q13608 Peroxisome assembly factor 2 chr6 Not Cancer Driver No 3 hippie, biogrid 72 177 9 9 11
PIK3C2A PIK3C2A O00443 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha chr11 Not Cancer Driver No 1 hippie, biogrid 187 350 43 43 0
PKN2 PKN2 Q16513 Serine/threonine-protein kinase N2 chr1 Not Cancer Driver No 1 hippie, biogrid 123 415 48 48 0
PLD2 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 hippie, biogrid 107 97 8 8 0
PPOX PPOX P50336 Protoporphyrinogen oxidase chr1 Not Cancer Driver No 1 hippie, biogrid 48 34 6 6 56
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 3 intact, hippie, biogrid 115 421 74 74 3
RAD51C RAD51C O43502 DNA repair protein RAD51 homolog 3 chr17 Not Cancer Driver No 1 hippie, biogrid 47 18 2 2 6
RFC1 RFC1 P35251 Replication factor C subunit 1 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 147 674 82 82 0
RIC8B_ENST00000392839 RIC8B Q9NVN3 Synembryn-B chr12 Not Cancer Driver No 1 hippie, biogrid 58 117 20 20 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 2 intact, hippie, biogrid 119 232 34 34 3
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 14 29 4 4 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 Not Cancer Driver No 1 hippie, biogrid 144 474 64 64 14
SH3BP4_ENST00000392011 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 Not Cancer Driver No 3 hippie, biogrid 143 241 43 43 0
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX Not Cancer Driver No 1 intact, hippie, biogrid 41 0 0 0 0
SMG8_ENST00000300917 SMG8 Q8ND04 Nonsense-mediated mRNA decay factor SMG8 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 145 412 57 57 1
TBC1D2B TBC1D2B Q9UPU7 TBC1 domain family member 2B chr15 Not Cancer Driver No 1 hippie, biogrid 118 419 43 43 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 188 320 58 58 0
THBS2 THBS2 P35442 Thrombospondin-2 chr6 Not Cancer Driver No 1 hippie 246 319 68 68 0
THBS3 THBS3 P49746 Thrombospondin-3 chr1 Not Cancer Driver No 1 hippie 100 283 24 24 0
THBS4 THBS4 P35443 Thrombospondin-4 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 137 281 40 40 0
TIGD5 TIGD5 Q53EQ6 Tigger transposable element-derived protein 5 chr8 Not Cancer Driver No 3 intact, hippie, biogrid 43 347 19 19 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 Compendium Yes 3 intact, hippie, biogrid 150 508 59 59 0
TRMT44 TRMT44 Q8IYL2 Probable tRNA (uracil-O(2)-)-methyltransferase chr4 Not Cancer Driver No 2 hippie, biogrid 57 260 16 16 0
TRO TRO Q12816 Trophinin chrX Not Cancer Driver No 3 hippie, biogrid 220 593 81 81 0
TTLL5 TTLL5 Q6EMB2 Tubulin polyglutamylase TTLL5 chr14 Not Cancer Driver No 1 hippie, biogrid 165 692 82 82 1
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 2 intact, hippie, biogrid 59 52 11 11 8
TUBA4A TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 3 intact, hippie, biogrid 73 39 4 4 5
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 2 intact, hippie, biogrid 67 53 10 10 12
TUBB8 TUBB8 Q3ZCM7 Tubulin beta-8 chain chr10 Not Cancer Driver No 3 intact, hippie, biogrid 103 53 18 18 13
UTP4 UTP4 Q969X6 U3 small nucleolar RNA-associated protein 4 homolog chr16 Not Cancer Driver No 1 hippie 63 34 7 7 0