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THAP1 ,THAP1 ,Q9NVV9
  • Uniprot Accession= Q9NVV9
  • Ensembl Transcript= ENST00000254250.7
  • Uniprot Name= THAP1
  • Name= THAP domain-containing protein 1
  • Chromosome= chr8
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 78
  • Number of Interaction partner in biogrid: 2
  • Number of Interaction partner in hippie: 109
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCF3 ABCF3 Q9NUQ8 ATP-binding cassette sub-family F member 3 chr3 Not Cancer Driver No 1 intact, hippie 109 136 19 19 0
ACOT7 ACOT7 O00154 Cytosolic acyl coenzyme A thioester hydrolase chr1 Not Cancer Driver No 2 intact, hippie 43 77 16 16 0
AEBP2 AEBP2 Q6ZN18 Zinc finger protein AEBP2 chr12 Not Cancer Driver No 1 hippie 41 335 25 25 0
AKAP17A AKAP17A Q02040 A-kinase anchor protein 17A chrX Not Cancer Driver No 2 intact, hippie 108 407 56 56 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 Census Yes 1 intact, hippie 474 2281 268 268 1
AP2B1_ENST00000621914 AP2B1 P63010 AP-2 complex subunit beta chr17 Not Cancer Driver No 2 intact, hippie 85 95 12 12 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARL6IP4_ENST00000543566 ARL6IP4 Q66PJ3-3 Isoform 3 of ADP-ribosylation factor-like protein 6-interacting protein 4 chr12 Not Cancer Driver No 1 hippie 16 386 15 15 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 3 intact, hippie 37 63 7 7 0
BEND7 BEND7 Q8N7W2-3 Isoform 3 of BEN domain-containing protein 7 chr10 Not Cancer Driver No 1 hippie 64 305 32 32 0
BYSL BYSL Q13895 Bystin chr6 Not Cancer Driver No 2 intact, hippie 38 176 14 14 0
C1orf216 C1orf216 Q8TAB5 UPF0500 protein C1orf216 chr1 Not Cancer Driver No 1 intact, hippie 22 199 21 21 0
C1orf35 MMTAG2 Q9BU76 Multiple myeloma tumor-associated protein 2 chr1 Not Cancer Driver No 3 intact 21 248 20 20 0
C4orf45 C4orf45 Q96LM5 Uncharacterized protein C4orf45 chr4 Not Cancer Driver No 1 intact, hippie 29 59 10 10 0
C7orf50 C7orf50 Q9BRJ6 Uncharacterized protein C7orf50 chr7 Not Cancer Driver No 1 hippie 21 126 17 17 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 intact, hippie 52 214 31 31 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 100 618 77 77 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 Census, Compendium Yes 1 hippie 19 198 19 19 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 Not Cancer Driver No 1 hippie 17 44 3 3 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact, hippie 287 145 18 18 151
CHD2 CHD2 O14647 Chromodomain-helicase-DNA-binding protein 2 chr15 Census, Compendium Yes 1 intact, hippie 222 1051 136 136 2
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 3 intact, hippie 71 75 8 8 4
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 Not Cancer Driver No 1 hippie 48 94 4 4 0
DCAF8 DCAF8 Q5TAQ9 DDB1- and CUL4-associated factor 8 chr1 Not Cancer Driver No 1 intact, hippie 85 273 55 55 1
DCTN3 DCTN3 O75935 Dynactin subunit 3 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 18 3 0 0 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 Not Cancer Driver No 1 hippie 96 514 64 64 0
EEF1AKNMT METTL13 Q8N6R0 eEF1A lysine and N-terminal methyltransferase chr1 Not Cancer Driver No 2 intact 91 76 16 16 0
FAM124A_ENST00000322475 FAM124A Q86V42 Protein FAM124A chr13 Not Cancer Driver No 1 intact, hippie 69 357 39 39 0
FAM133A_ENST00000332647 FAM133A Q8N9E0 Protein FAM133A chrX Not Cancer Driver No 2 intact, hippie 59 248 59 59 0
FAM9A_ENST00000381003 FAM9A Q8IZU1 Protein FAM9A chrX Not Cancer Driver No 1 intact, hippie 77 332 77 77 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 Not Cancer Driver No 1 intact, hippie 56 34 11 11 2
FGF11 FGF11 Q92914 Fibroblast growth factor 11 chr17 Not Cancer Driver No 1 intact, hippie 20 68 5 5 0
FGF12 FGF12 P61328 Fibroblast growth factor 12 chr3 Not Cancer Driver No 1 intact, hippie 74 102 30 30 1
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 1 intact, hippie 68 388 42 42 0
GAPDHS GAPDHS O14556 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific chr19 Not Cancer Driver No 2 intact, hippie, biogrid 71 111 19 19 0
GAS8 GAS8 O95995 Dynein regulatory complex subunit 4 chr16 Not Cancer Driver No 1 hippie 54 232 29 29 1
GCOM1_ENST00000380569 GCOM1 P0CAP1-11 Isoform 11 of Myocardial zonula adherens protein chr15 Not Cancer Driver No 1 hippie 96 462 83 83 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 1 intact, hippie 65 288 42 42 62
GPATCH2L GPATCH2L Q9NWQ4 G patch domain-containing protein 2-like chr14 Not Cancer Driver No 2 intact, hippie 63 380 48 48 0
HCFC1 HCFC1 P51610 Host cell factor 1 chrX Not Cancer Driver No 2 intact, hippie 280 1345 181 181 1
HNRNPLL HNRNPLL Q8WVV9 Heterogeneous nuclear ribonucleoprotein L-like chr2 Not Cancer Driver No 1 intact, hippie 37 149 13 13 0
INO80B INO80B Q9C086 INO80 complex subunit B chr2 Not Cancer Driver No 1 hippie 35 336 33 33 0
KANK2_ENST00000586659 KANK2 Q63ZY3 KN motif and ankyrin repeat domain-containing protein 2 chr19 Not Cancer Driver No 1 hippie 107 531 71 71 3
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KLF12 KLF12 Q9Y4X4 Krueppel-like factor 12 chr13 Not Cancer Driver No 1 hippie 60 338 50 50 0
KRTAP10-7 KRTAP10-7 P60409 Keratin-associated protein 10-7 chr21 Not Cancer Driver No 1 intact, hippie 70 0 0 0 0
L3MBTL2 L3MBTL2 Q969R5 Lethal(3)malignant brain tumor-like protein 2 chr22 Not Cancer Driver No 1 intact, hippie 95 210 38 38 0
LASP1 LASP1 Q14847 LIM and SH3 domain protein 1 chr17 Census Yes 1 hippie 29 198 24 24 0
LMNB2 LMNB2 Q03252 Lamin-B2 chr19 Not Cancer Driver No 1 intact, hippie 67 428 42 42 5
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 Not Cancer Driver No 1 intact, hippie 30 1 0 0 0
LNX1 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 1 intact, hippie 117 261 40 40 0
MFAP1 MFAP1 P55081 Microfibrillar-associated protein 1 chr15 Not Cancer Driver No 1 hippie 58 377 53 53 0
MIS18A MIS18A Q9NYP9 Protein Mis18-alpha chr21 Not Cancer Driver No 1 intact, hippie 20 15 1 1 0
MORF4L1 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 Not Cancer Driver No 1 hippie 43 163 17 17 0
MORF4L2_ENST00000433176 MORF4L2 Q15014 Mortality factor 4-like protein 2 chrX Not Cancer Driver No 1 intact, hippie 44 136 21 21 0
MRPL11 MRPL11 Q9Y3B7 39S ribosomal protein L11, mitochondrial chr11 Not Cancer Driver No 2 intact, hippie 25 12 1 1 0
MRPL53 MRPL53 Q96EL3 39S ribosomal protein L53, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 20 22 1 1 0
NDUFAB1_ENST00000007516 NDUFAB1 O14561 Acyl carrier protein, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 23 0 0 0 0
NDUFV2 NDUFV2 P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial chr18 Not Cancer Driver No 1 hippie 40 69 15 15 0
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX Not Cancer Driver No 1 intact, hippie 80 409 77 77 3
NKAPD1_ENST00000420986 NKAPD1 Q6ZUT1 Uncharacterized protein NKAPD1 chr11 Not Cancer Driver No 2 intact, hippie 35 261 31 31 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 Not Cancer Driver No 1 hippie 168 347 38 38 0
NUP62 NUP62 P37198 Nuclear pore glycoprotein p62 chr19 Not Cancer Driver No 5 intact, hippie 76 377 56 56 1
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 Not Cancer Driver No 1 hippie 35 327 33 33 0
PHF1 PHF1 O43189 PHD finger protein 1 chr6 Not Cancer Driver No 1 hippie 62 277 29 29 0
PHF19_ENST00000373896 PHF19 Q5T6S3 PHD finger protein 19 chr9 Not Cancer Driver No 1 intact, hippie 66 129 19 19 0
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 Not Cancer Driver No 1 intact, hippie 70 24 10 10 0
PMP22_ENST00000612492 PMP22 Q01453 Peripheral myelin protein 22 chr17 Not Cancer Driver No 1 intact 20 0 0 0 37
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 Not Cancer Driver No 1 hippie 53 177 23 23 4
POLR2L POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 Not Cancer Driver No 1 intact, hippie 10 0 0 0 0
POLR2M_ENST00000464277 POLR2M Q6EEV4 DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5 chr15 Not Cancer Driver No 1 hippie 4 121 4 4 0
POU6F2 POU6F2 P78424 POU domain, class 6, transcription factor 2 chr7 Not Cancer Driver No 1 intact, hippie 165 571 144 144 1
PPIG_ENST00000448752 PPIG Q13427 Peptidyl-prolyl cis-trans isomerase G chr2 Not Cancer Driver No 1 intact, hippie 116 644 96 96 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 intact, hippie 72 124 17 17 0
QKI QKI Q96PU8 Protein quaking chr6 Census, Compendium Yes 1 intact, hippie 52 174 27 27 0
RAD54L2 RAD54L2 Q9Y4B4 Helicase ARIP4 chr3 Not Cancer Driver No 1 hippie 194 753 97 97 0
RALY RALY Q9UKM9 RNA-binding protein Raly chr20 Not Cancer Driver No 1 intact, hippie 58 187 32 32 0
RALYL_ENST00000521268 RALYL Q86SE5 RNA-binding Raly-like protein chr8 Not Cancer Driver No 3 intact, hippie 111 181 75 75 0
RBM10_ENST00000377604 RBM10 P98175 RNA-binding protein 10 chrX Census, Compendium Yes 1 hippie 112 777 99 99 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RIPPLY1 RIPPLY1 Q0D2K3 Protein ripply1 chrX Not Cancer Driver No 2 intact, hippie 19 56 8 8 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RPL22 RPL22 P35268 60S ribosomal protein L22 chr1 Census, Compendium Yes 1 intact, hippie 26 15 1 1 0
RPS25 RPS25 P62851 40S ribosomal protein S25 chr11 Not Cancer Driver No 1 intact, hippie 16 60 8 8 0
RRM1 RRM1 P23921 Ribonucleoside-diphosphate reductase large subunit chr11 Not Cancer Driver No 1 intact 74 41 7 7 0
SAP30BP SAP30BP Q9UHR5 SAP30-binding protein chr17 Not Cancer Driver No 1 hippie 25 233 19 19 0
SERF2_ENST00000381359 SERF2 P84101 Small EDRK-rich factor 2 chr15 Not Cancer Driver No 1 hippie 11 59 11 11 0
SLU7 SLU7 O95391 Pre-mRNA-splicing factor SLU7 chr5 Not Cancer Driver No 1 intact, hippie 75 436 63 63 0
SNURF SNURF Q9Y675 SNRPN upstream reading frame protein chr15 Not Cancer Driver No 1 intact 19 67 19 19 0
SPANXN2 SPANXN2 Q5MJ10 Sperm protein associated with the nucleus on the X chromosome N2 chrX Not Cancer Driver No 1 intact, hippie 106 180 106 106 0
SREK1IP1 SREK1IP1 Q8N9Q2 Protein SREK1IP1 chr5 Not Cancer Driver No 1 intact, hippie 20 132 18 18 0
STAG1 STAG1 Q8WVM7 Cohesin subunit SA-1 chr3 Census Yes 1 intact, hippie 226 391 66 66 8
STRBP_ENST00000348403 STRBP Q96SI9 Spermatid perinuclear RNA-binding protein chr9 Not Cancer Driver No 4 intact, hippie 74 306 31 31 0
TCEA2 TCEA2 Q15560 Transcription elongation factor A protein 2 chr20 Not Cancer Driver No 1 hippie 45 194 40 40 0
TCEANC_ENST00000380600 TCEANC Q8N8B7 Transcription elongation factor A N-terminal and central domain-containing protein chrX Not Cancer Driver No 1 intact, hippie 38 138 12 12 0
THAP1 THAP1 Q9NVV9 THAP domain-containing protein 1 chr8 Not Cancer Driver No 6 intact, hippie 19 76 8 8 45
TOR1A TOR1A O14656 Torsin-1A chr9 Not Cancer Driver No 1 intact 33 0 0 0 3
TPM3 TPM3 P06753 Tropomyosin alpha-3 chain chr1 Census Yes 2 intact, hippie 35 230 27 27 21
TRAF5_ENST00000336184 TRAF5 O00463 TNF receptor-associated factor 5 chr1 Not Cancer Driver No 1 hippie 61 59 5 5 0
TRIM26 TRIM26 Q12899 Tripartite motif-containing protein 26 chr6 Not Cancer Driver No 2 intact, hippie 67 153 16 16 0
TRIP10 TRIP10 Q15642 Cdc42-interacting protein 4 chr19 Not Cancer Driver No 1 hippie 72 460 61 61 0
TTLL10_ENST00000379289 TTLL10 Q6ZVT0 Inactive polyglycylase TTLL10 chr1 Not Cancer Driver No 1 hippie 64 314 22 22 0
TXN2_ENST00000403313 TXN2 Q99757 Thioredoxin, mitochondrial chr22 Not Cancer Driver No 1 intact, hippie 22 34 4 4 0
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 2 intact, hippie 78 191 28 28 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 intact, hippie 16 16 3 3 0
VCX2 VCX2 Q9H322 Variable charge X-linked protein 2 chrX Not Cancer Driver No 1 intact, hippie 14 139 14 14 0
WDYHV1 NTAQ1 Q96HA8 Protein N-terminal glutamine amidohydrolase chr8 Not Cancer Driver No 4 intact 38 26 3 3 0
WT1_ENST00000379079 WT1 P19544-6 Isoform 6 of Wilms tumor protein chr11 Census, Compendium Yes 1 hippie 69 194 43 43 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie 65 62 10 10 0
ZBTB48 ZBTB48 P10074 Telomere zinc finger-associated protein chr1 Not Cancer Driver No 1 hippie 53 237 16 16 0
ZCCHC10 ZCCHC10 Q8TBK6 Zinc finger CCHC domain-containing protein 10 chr5 Not Cancer Driver No 3 intact, hippie 12 144 11 11 0
ZGPAT ZGPAT Q8N5A5 Zinc finger CCCH-type with G patch domain-containing protein chr20 Not Cancer Driver No 1 intact, hippie 75 346 49 49 0
ZNF385C ZNF385C Q66K41 Zinc finger protein 385C chr17 Not Cancer Driver No 2 intact, hippie 23 260 15 15 0
ZNF408 ZNF408 Q9H9D4 Zinc finger protein 408 chr11 Not Cancer Driver No 2 intact, hippie 79 432 40 40 2
ZNF526 ZNF526 Q8TF50 Zinc finger protein 526 chr19 Not Cancer Driver No 1 intact, hippie 86 421 56 56 0