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TESK2 ,TESK2 ,Q96S53
  • Uniprot Accession= Q96S53
  • Ensembl Transcript= ENST00000372086.3
  • Uniprot Name= TESK2
  • Name= Dual specificity testis-specific protein kinase 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 54
  • Number of Interaction partner in biogrid: 24
  • Number of Interaction partner in hippie: 92
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 Census Yes 2 intact, hippie 248 1247 180 180 0
AGAP1 AGAP1 Q9UPQ3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie 163 403 81 81 0
AHSA1 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 46 146 17 17 0
ANKRD34A ANKRD34A Q69YU3 Ankyrin repeat domain-containing protein 34A chr1 Not Cancer Driver No 2 intact, hippie 90 410 78 78 0
CACYBP CACYBP Q9HB71 Calcyclin-binding protein chr1 Not Cancer Driver No 1 hippie, biogrid 27 92 10 10 0
CAD CAD P27708 CAD protein chr2 Not Cancer Driver No 1 intact, hippie, biogrid 287 368 52 52 1
CAMSAP2 CAMSAP2 Q08AD1 Calmodulin-regulated spectrin-associated protein 2 chr1 Not Cancer Driver No 1 hippie 176 1025 127 127 0
CBY1_ENST00000216029 CBY1 Q9Y3M2 Protein chibby homolog 1 chr22 Not Cancer Driver No 2 intact, hippie 13 98 11 11 0
CDC25B CDC25B P30305 M-phase inducer phosphatase 2 chr20 Not Cancer Driver No 1 hippie 80 328 43 43 0
CDC25C CDC25C P30307 M-phase inducer phosphatase 3 chr5 Not Cancer Driver No 2 intact, hippie 61 224 26 26 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 52 214 31 31 0
CDK16_ENST00000357227 CDK16 Q00536 Cyclin-dependent kinase 16 chrX Not Cancer Driver No 1 hippie 55 139 30 30 0
CFL1_ENST00000308162 CFL1 P23528 Cofilin-1 chr11 Not Cancer Driver No 1 hippie 21 4 0 0 0
CGN CGN Q9P2M7 Cingulin chr1 Not Cancer Driver No 2 intact, hippie 152 1179 149 149 0
CHPF CHPF Q8IZ52 Chondroitin sulfate synthase 2 chr2 Not Cancer Driver No 1 hippie, biogrid 88 194 18 18 0
CPLANE1 CPLANE1 Q9H799 Ciliogenesis and planar polarity effector 1 chr5 Not Cancer Driver No 1 hippie 330 1364 177 177 7
CPVL_ENST00000265394 CPVL Q9H3G5 Probable serine carboxypeptidase CPVL chr7 Not Cancer Driver No 1 intact, hippie, biogrid 81 0 0 0 0
DCLK1 DCLK1 O15075 Serine/threonine-protein kinase DCLK1 chr13 Not Cancer Driver No 1 hippie 209 252 77 77 0
DENND1A DENND1A Q8TEH3 DENN domain-containing protein 1A chr9 Not Cancer Driver No 1 hippie 117 589 76 76 0
DENND4A_ENST00000431932 DENND4A Q7Z401 C-myc promoter-binding protein chr15 Not Cancer Driver No 1 hippie 199 570 64 64 0
DENND4C_ENST00000602925 DENND4C Q5VZ89 DENN domain-containing protein 4C chr9 Not Cancer Driver No 2 intact, hippie 190 710 69 69 0
DEPDC1B DEPDC1B Q8WUY9 DEP domain-containing protein 1B chr5 Not Cancer Driver No 2 intact, hippie 76 52 6 6 0
DSTN DSTN P60981 Destrin chr20 Not Cancer Driver No 1 hippie 18 0 0 0 0
EDC3 EDC3 Q96F86 Enhancer of mRNA-decapping protein 3 chr15 Not Cancer Driver No 1 hippie 43 185 22 22 1
EID1 EID1 Q9Y6B2 EP300-interacting inhibitor of differentiation 1 chr15 Not Cancer Driver No 1 hippie 22 159 17 17 0
EIF4E2 EIF4E2 O60573 Eukaryotic translation initiation factor 4E type 2 chr2 Not Cancer Driver No 2 intact, hippie 27 80 5 5 0
FAM110A_ENST00000246100 FAM110A Q9BQ89 Protein FAM110A chr20 Not Cancer Driver No 2 intact, hippie 20 244 12 12 0
FAM110B FAM110B Q8TC76 Protein FAM110B chr8 Not Cancer Driver No 2 intact, hippie 75 299 65 65 0
FAM53C_ENST00000434981 FAM53C Q9NYF3 Protein FAM53C chr5 Not Cancer Driver No 2 intact, hippie 51 296 45 45 0
FKBP5 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 70 150 20 20 0
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 Not Cancer Driver No 1 hippie 85 537 73 73 0
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 Not Cancer Driver No 1 intact, hippie 327 117 16 16 0
GIGYF1_ENST00000646601 GIGYF1 O75420 GRB10-interacting GYF protein 1 chr7 Not Cancer Driver No 1 hippie 138 857 115 115 0
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 Not Cancer Driver No 1 hippie 176 1096 158 158 6
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 2 intact, hippie 182 749 132 132 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 Not Cancer Driver No 1 hippie 91 570 50 50 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 3 intact, hippie, biogrid 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 3 intact, hippie, biogrid 100 254 43 43 0
ILVBL ILVBL A1L0T0 2-hydroxyacyl-CoA lyase 2 chr19 Not Cancer Driver No 1 hippie, biogrid 86 30 1 1 0
INPP5E INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 Not Cancer Driver No 2 intact, hippie 43 272 16 16 15
IRS4 IRS4 O14654 Insulin receptor substrate 4 chrX Census, Compendium Yes 1 intact, hippie, biogrid 297 798 203 203 0
KCTD3 KCTD3 Q9Y597 BTB/POZ domain-containing protein KCTD3 chr1 Not Cancer Driver No 2 intact, hippie 113 324 45 45 0
KIF13B KIF13B Q9NQT8 Kinesin-like protein KIF13B chr8 Not Cancer Driver No 1 hippie 187 968 82 82 0
KIF1C KIF1C O43896 Kinesin-like protein KIF1C chr17 Not Cancer Driver No 2 intact, hippie 131 695 94 94 1
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 2 intact, hippie 114 404 58 58 0
LARP1 LARP1 Q6PKG0-3 Isoform 2 of La-related protein 1 chr5 Not Cancer Driver No 1 hippie 136 726 100 100 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 88 687 81 81 0
LPIN3_ENST00000373257 LPIN3 Q9BQK8 Phosphatidate phosphatase LPIN3 chr20 Not Cancer Driver No 2 intact, hippie 91 472 50 50 0
LRFN1 LRFN1 Q9P244 Leucine-rich repeat and fibronectin type III domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 96 278 37 37 0
MAGI1 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 Not Cancer Driver No 2 intact, hippie 260 1212 220 220 0
MAP3K21 MAP3K21 Q5TCX8 Mitogen-activated protein kinase kinase kinase 21 chr1 Not Cancer Driver No 2 intact, hippie 191 658 112 112 0
MAPKAP1 MAPKAP1 Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 chr9 Not Cancer Driver No 1 hippie 70 173 25 25 0
MAST3 MAST3 O60307 Microtubule-associated serine/threonine-protein kinase 3 chr19 Not Cancer Driver No 2 intact, hippie 169 783 100 100 0
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 Not Cancer Driver No 1 intact 26 384 25 25 0
MELK MELK Q14680 Maternal embryonic leucine zipper kinase chr9 Not Cancer Driver No 1 hippie 76 162 24 24 0
NADK_ENST00000341991 NADK O95544 NAD kinase chr1 Not Cancer Driver No 1 hippie 59 91 18 18 0
NAV1 NAV1 Q8NEY1 Neuron navigator 1 chr1 Not Cancer Driver No 1 intact 225 1455 167 167 0
NF1 NF1 P21359 Neurofibromin chr17 Census, Compendium Yes 2 intact, hippie 375 406 47 47 85
PHLDB2 PHLDB2 Q86SQ0 Pleckstrin homology-like domain family B member 2 chr3 Not Cancer Driver No 1 hippie 235 1030 190 190 0
PI4KA PI4KA P42356 Phosphatidylinositol 4-kinase alpha chr22 Not Cancer Driver No 1 hippie, biogrid 267 142 11 11 1
PLEKHA5_ENST00000299275 PLEKHA5 Q9HAU0 Pleckstrin homology domain-containing family A member 5 chr12 Not Cancer Driver No 2 intact, hippie 144 869 114 114 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 2 intact, hippie 152 919 121 121 0
POLR2B_ENST00000314595 POLR2B P30876 DNA-directed RNA polymerase II subunit RPB2 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 166 173 25 25 0
POLR3A POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 155 113 17 17 15
PPM1H PPM1H Q9ULR3 Protein phosphatase 1H chr12 Not Cancer Driver No 1 hippie 71 140 23 23 0
PTPN14 PTPN14 Q15678 Tyrosine-protein phosphatase non-receptor type 14 chr1 Compendium Yes 1 hippie 173 582 99 99 0
RAB3IP RAB3IP Q96QF0 Rab-3A-interacting protein chr12 Not Cancer Driver No 1 hippie 85 227 33 33 0
RASAL2_ENST00000462775 RASAL2 Q9UJF2 Ras GTPase-activating protein nGAP chr1 Not Cancer Driver No 2 intact, hippie 164 606 86 86 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 Not Cancer Driver No 1 hippie 176 241 21 21 0
RTKN RTKN Q9BST9 Rhotekin chr2 Not Cancer Driver No 1 hippie 67 265 35 35 0
SH3BP4_ENST00000392011 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 Not Cancer Driver No 1 hippie 143 241 43 43 0
SH3PXD2A_ENST00000369774 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 Not Cancer Driver No 1 hippie 141 797 101 101 0
SH3RF3 SH3RF3 Q8TEJ3 E3 ubiquitin-protein ligase SH3RF3 chr2 Not Cancer Driver No 1 hippie 98 564 53 53 0
SIPA1L1 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 Not Cancer Driver No 2 intact, hippie 321 1175 226 226 0
SRGAP2 SRGAP2 O75044 SLIT-ROBO Rho GTPase-activating protein 2 chr1 Not Cancer Driver No 1 hippie 122 541 71 71 0
SRSF12 SRSF12 Q8WXF0 Serine/arginine-rich splicing factor 12 chr6 Not Cancer Driver No 2 intact, hippie 36 205 31 31 0
STARD13 STARD13 Q9Y3M8 StAR-related lipid transfer protein 13 chr13 Not Cancer Driver No 1 hippie 177 494 78 78 0
SUGT1 SUGT1 Q9Y2Z0 Protein SGT1 homolog chr13 Not Cancer Driver No 1 intact, hippie, biogrid 31 119 5 5 0
SYDE1 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 Not Cancer Driver No 2 intact, hippie 62 412 27 27 0
TBC1D25 TBC1D25 Q3MII6 TBC1 domain family member 25 chrX Not Cancer Driver No 2 intact, hippie 114 256 37 37 0
TESK1_ENST00000336395 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 63 339 35 35 0
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 Not Cancer Driver No 2 intact, hippie 370 810 194 194 0
UBR5 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 Census, Compendium Yes 1 intact, hippie, biogrid 340 1296 162 162 0
USP21_ENST00000289865 USP21 Q9UK80 Ubiquitin carboxyl-terminal hydrolase 21 chr1 Not Cancer Driver No 2 intact, hippie 95 230 47 47 0
USP9Y USP9Y O00507 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y chrY Not Cancer Driver No 1 intact, hippie, biogrid 83 349 6 6 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 4 intact, hippie, biogrid 22 109 4 4 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 intact, hippie, biogrid 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 3 intact, hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 3 intact, hippie, biogrid 15 55 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 3 intact, hippie, biogrid 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 intact, hippie, biogrid 30 81 10 10 0
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 70 271 27 27 0
ZBTB21 ZBTB21 Q9ULJ3 Zinc finger and BTB domain-containing protein 21 chr21 Not Cancer Driver No 2 intact, hippie 136 645 75 75 0
ZNF638 ZNF638 Q14966 Zinc finger protein 638 chr2 Not Cancer Driver No 2 intact, hippie 243 1667 209 209 0