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TDRKH_ENST00000368827 ,TDRKH ,Q9Y2W6
  • Number of Interaction partner in intact: 19
  • Number of Interaction partner in biogrid: 49
  • Number of Interaction partner in hippie: 67
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 2 intact, hippie, biogrid 88 166 22 22 11
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
ARHGAP19 ARHGAP19 Q14CB8 Rho GTPase-activating protein 19 chr10 Not Cancer Driver No 2 hippie, biogrid 70 179 21 21 0
ATG2A ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 Not Cancer Driver No 1 intact, hippie 228 887 124 124 0
AZGP1 AZGP1 P25311 Zinc-alpha-2-glycoprotein chr7 Not Cancer Driver No 1 intact, hippie, biogrid 59 41 10 10 0
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 171 425 68 68 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie, biogrid 96 505 91 91 0
CNN3 CNN3 Q15417 Calponin-3 chr1 Not Cancer Driver No 1 hippie 30 173 17 17 0
COX14_ENST00000550654 COX14 Q96I36 Cytochrome c oxidase assembly protein COX14 chr12 Not Cancer Driver No 1 intact, hippie 4 7 0 0 1
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 37 21 5 5 5
ESPL1 ESPL1 Q14674 Separin chr12 Not Cancer Driver No 1 hippie, biogrid 211 380 39 39 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 58 176 15 15 0
FAM160B2 FHIP2B Q86V87 FHF complex subunit HOOK interacting protein 2B chr8 Not Cancer Driver No 1 intact 75 139 14 14 0
FAM193B FAM193B Q96PV7-3 Isoform 3 of Protein FAM193B chr5 Not Cancer Driver No 1 biogrid 39 743 36 36 0
FAM25A FAM25A B3EWG3 Protein FAM25A chr10 Not Cancer Driver No 1 hippie 4 83 4 4 0
FAM25C FAM25C B3EWG5 Protein FAM25C chr10 Not Cancer Driver No 1 intact 2 83 2 2 0
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 Not Cancer Driver No 1 hippie, biogrid 25 6 0 0 0
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 71 160 25 25 0
GGCT GGCT O75223 Gamma-glutamylcyclotransferase chr7 Not Cancer Driver No 1 hippie, biogrid 25 51 2 2 0
GPRASP2 GPRASP2 Q96D09 G-protein coupled receptor-associated sorting protein 2 chrX Not Cancer Driver No 1 hippie, biogrid 133 506 81 81 1
HASPIN HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 Not Cancer Driver No 1 hippie 87 373 36 36 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 intact, hippie 36 25 6 6 0
HSD3B7 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 43 27 5 5 2
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 Not Cancer Driver No 1 hippie 141 298 80 80 0
LANCL2 LANCL2 Q9NS86 LanC-like protein 2 chr7 Not Cancer Driver No 1 intact, hippie 71 44 5 5 0
LCN1 LCN1 P31025 Lipocalin-1 chr9 Not Cancer Driver No 1 hippie, biogrid 31 69 17 17 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 Not Cancer Driver No 2 hippie, biogrid 70 411 58 58 0
MFN2_ENST00000444836 MFN2 O95140 Mitofusin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 80 81 9 9 20
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
MTCH1 MTCH1 Q9NZJ7 Mitochondrial carrier homolog 1 chr6 Not Cancer Driver No 1 hippie, biogrid 31 102 2 2 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 45 11 0 0 0
MTX2 MTX2 O75431 Metaxin-2 chr2 Not Cancer Driver No 1 hippie, biogrid 33 0 0 0 0
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX Census, Compendium Yes 1 intact, hippie, biogrid 101 349 64 64 0
OCIAD1 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 37 169 25 25 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 114 131 17 17 60
PEX14 PEX14 O75381 Peroxisomal membrane protein PEX14 chr1 Not Cancer Driver No 1 hippie, biogrid 38 266 28 28 0
PEX3 PEX3 P56589 Peroxisomal biogenesis factor 3 chr6 Not Cancer Driver No 1 hippie, biogrid 31 24 0 0 2
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 31 26 4 4 0
PIWIL1 PIWIL1 Q96J94 Piwi-like protein 1 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 202 172 37 37 0
PIWIL4 PIWIL4 Q7Z3Z4 Piwi-like protein 4 chr11 Not Cancer Driver No 1 hippie, biogrid 115 89 11 11 0
PLD6 PLD6 Q8N2A8 Mitochondrial cardiolipin hydrolase chr17 Not Cancer Driver No 2 hippie, biogrid 27 24 6 6 0
PLEC PLEC Q15149 Plectin chr8 Not Cancer Driver No 1 intact, hippie, biogrid 677 2130 272 272 2
PLGRKT PLGRKT Q9HBL7 Plasminogen receptor (KT) chr9 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie, biogrid 49 140 25 25 0
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 Not Cancer Driver No 1 hippie 14 19 2 2 1
PXMP2 PXMP2 Q9NR77 Peroxisomal membrane protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 15 0 0 0 0
RAB3B RAB3B P20337 Ras-related protein Rab-3B chr1 Not Cancer Driver No 1 hippie, biogrid 36 25 6 6 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 32 65 15 15 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 biogrid 27 11 0 0 4
RHOT2 RHOT2 Q8IXI1 Mitochondrial Rho GTPase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 52 79 5 5 0
RMDN3 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 45 196 17 17 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
S100A14_ENST00000368701 S100A14 Q9HCY8 Protein S100-A14 chr1 Not Cancer Driver No 1 hippie, biogrid 15 55 9 9 0
SELENON SELENON Q9NZV5 Selenoprotein N chr1 Not Cancer Driver No 1 hippie 53 93 5 5 11
SENP1 SENP1 Q9P0U3 Sentrin-specific protease 1 chr12 Not Cancer Driver No 1 hippie, biogrid 64 355 44 44 0
SLC25A46 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 Not Cancer Driver No 1 hippie, biogrid 37 96 2 2 4
SNRNP25 SNRNP25 Q9BV90 U11/U12 small nuclear ribonucleoprotein 25 kDa protein chr16 Not Cancer Driver No 1 intact, hippie 14 5 1 1 0
SRSF1 SRSF1 Q07955 Serine/arginine-rich splicing factor 1 chr17 Not Cancer Driver No 1 hippie, biogrid 41 198 34 34 0
SUN2_ENST00000405510 SUN2 Q9UH99 SUN domain-containing protein 2 chr22 Not Cancer Driver No 1 hippie, biogrid 74 214 18 18 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 Not Cancer Driver No 1 hippie, biogrid 33 361 20 20 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 28 310 16 16 0
TOMM20 TOMM20 Q15388 Mitochondrial import receptor subunit TOM20 homolog chr1 Not Cancer Driver No 1 hippie 8 25 1 1 0
TOMM22 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 intact, hippie 18 83 9 9 0
TOP3B_ENST00000357179 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 Not Cancer Driver No 1 hippie, biogrid 102 151 17 17 0
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 Not Cancer Driver No 1 intact 97 385 80 80 0
ZBTB34 ZBTB34 Q8NCN2 Zinc finger and BTB domain-containing protein 34 chr9 Not Cancer Driver No 2 hippie, biogrid 57 268 26 26 0
ZFP90_ENST00000563169 ZFP90 Q8TF47 Zinc finger protein 90 homolog chr16 Not Cancer Driver No 1 intact, hippie 90 310 46 46 0
ZNF148_ENST00000485866 ZNF148 Q9UQR1 Zinc finger protein 148 chr3 Compendium Yes 1 hippie, biogrid 125 600 88 88 0
ZNF281_ENST00000367353 ZNF281 Q9Y2X9 Zinc finger protein 281 chr1 Not Cancer Driver No 1 hippie, biogrid 92 709 67 67 0
ZNF644_ENST00000370440 ZNF644 Q9H582 Zinc finger protein 644 chr1 Not Cancer Driver No 1 hippie, biogrid 176 870 108 108 4